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915191-42-3,MFCD17166964
Catalog No.:AA00GU6B

915191-42-3 | MF498

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$98.00   $68.00
- +
5mg
≥98%
in stock  
$432.00   $302.00
- +
10mg
≥98%
in stock  
$765.00   $535.00
- +
25mg
≥98%
in stock  
$1,670.00   $1,169.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00GU6B
Chemical Name:
MF498
CAS Number:
915191-42-3
Molecular Formula:
C32H33N3O7S
Molecular Weight:
603.6853
MDL Number:
MFCD17166964
SMILES:
CCOc1c2CN(C(=O)c2c(c2c1nccc2)OCC)c1ccc(cc1C)CS(=O)(=O)NC(=O)Cc1ccccc1OC
Properties
Computed Properties
 
Complexity:
1070  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
11  
XLogP3:
4.1  

Literature

Title: MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.

Journal: The Journal of pharmacology and experimental therapeutics 20080501

Title: Clark P, et al. MF498 [N-{-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo,4-gquinolin-7-yl)-3-methylbenzylsulfonyl}-2-(2-methoxyphenyl)acetamide, a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. J Pharmacol Exp Ther. 2008 May;325(2):425-434.

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