Title: MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.
Journal: The Journal of pharmacology and experimental therapeutics 20080501
Title: Clark P, et al. MF498 [N-{-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo,4-gquinolin-7-yl)-3-methylbenzylsulfonyl}-2-(2-methoxyphenyl)acetamide, a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. J Pharmacol Exp Ther. 2008 May;325(2):425-434.