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900185-02-6,MFCD17019338
Catalog No.:AA00GU6M

900185-02-6 | PIK-294

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$15.00   $11.00
- +
5mg
98+%
in stock  
$36.00   $25.00
- +
10mg
98+%
in stock  
$54.00   $38.00
- +
25mg
98+%
in stock  
$90.00   $63.00
- +
50mg
98+%
in stock  
$151.00   $106.00
- +
100mg
98+%
in stock  
$255.00   $178.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00GU6M
Chemical Name:
PIK-294
CAS Number:
900185-02-6
Molecular Formula:
C28H23N7O2
Molecular Weight:
489.5279
MDL Number:
MFCD17019338
SMILES:
Oc1cccc(c1)c1nn(c2c1c(N)ncn2)Cc1nc2cccc(c2c(=O)n1c1ccccc1C)C
Properties
Computed Properties
 
Complexity:
870  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
4.2  

Literature

Title: PI3Kδ and PI3Kγ as targets for autoimmune and inflammatory diseases.

Journal: Journal of medicinal chemistry 20121025

Title: Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.

Journal: Nature chemical biology 20081101

Title: Knight ZA, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125(4):733-47.

Title: Martin KJ, et al. The role of phosphoinositide 3-kinases in neutrophil migration in 3D collagen gels. PLoS One. 2015 Feb 6;10(2):e0116250.

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SDS
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Tags:900185-02-6 Molecular Formula|900185-02-6 MDL|900185-02-6 SMILES|900185-02-6 PIK-294