Title: Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats.
Journal: Journal of medicinal chemistry 20110113
Title: The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100901
Title: Selective potentiation of the metabotropic glutamate receptor subtype 2 blocks phencyclidine-induced hyperlocomotion and brain activation.
Journal: Neuroscience 20100616
Title: Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor.
Journal: Bioorganic & medicinal chemistry letters 20100101
Title: Modulation of group II metabotropic glutamate receptor (mGlu2) elicits common changes in rat and mice sleep-wake architecture.
Journal: European journal of pharmacology 20090128
Title: Promise of mGluR2/3 activators in psychiatry.
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101
Title: A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis.
Journal: Molecular pharmacology 20070801
Title: Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20060701
Title: Biphenyl-indanones: allosteric potentiators of the metabotropic glutamate subtype 2 receptor.
Journal: Bioorganic & medicinal chemistry letters 20051001
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