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91987-74-5,MFCD01863112
Catalog No.:AA00H0GY

91987-74-5 | ((1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl)tetrakis(methylene))tetraphosphonic acid

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250mg
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$26.00   $18.00
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1g
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$102.00   $71.00
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5g
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$402.00   $281.00
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00H0GY
Chemical Name:
((1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl)tetrakis(methylene))tetraphosphonic acid
CAS Number:
91987-74-5
Molecular Formula:
C12H32N4O12P4
Molecular Weight:
548.2971
MDL Number:
MFCD01863112
SMILES:
OP(=O)(CN1CCN(CCN(CCN(CC1)CP(=O)(O)O)CP(=O)(O)O)CP(=O)(O)O)O
NSC Number:
681106
Properties
Computed Properties
 
Complexity:
634  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
8  
Rotatable Bond Count:
8  
XLogP3:
-15.9  

Literature

Title: A preclinical investigation of the saturation and dosimetry of 153Sm-DOTMP as a bone-seeking radiopharmaceutical.

Journal: Nuclear medicine and biology 20120801

Title: Pilot study of targeted skeletal radiation therapy for bone-only metastatic breast cancer.

Journal: Clinical breast cancer 20090801

Title: Kinetics and thermodynamics of adsorption on hydroxyapatite of the [160Tb]terbium complexes of the bone-targeting ligands DOTP and BPPED.

Journal: Langmuir : the ACS journal of surfaces and colloids 20090217

Title: Synthesis of 99mTc-DOTMP and its preclinical evaluation as a multidentate imaging agent for skeletal metastases.

Journal: Cancer biotherapy & radiopharmaceuticals 20090201

Title: Synthesis, potentiometric, kinetic, and NMR Studies of 1,4,7,10-tetraazacyclododecane-1,7-bis(acetic acid)-4,10-bis(methylenephosphonic acid) (DO2A2P) and its complexes with Ca(II), Cu(II), Zn(II) and lanthanide(III) ions.

Journal: Inorganic chemistry 20080505

Title: Results of a retrospective single institution analysis of targeted skeletal radiotherapy with (166)Holmium-DOTMP as conditioning regimen for autologous stem cell transplant for patients with multiple myeloma. Impact on transplant outcomes.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20070501

Title: 166Ho-DOTMP radiation-absorbed dose estimation for skeletal targeted radiotherapy.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060301

Title: Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents.

Journal: Anticancer research 20040101

Title: 166Ho-DOTMP plus melphalan followed by peripheral blood stem cell transplantation in patients with multiple myeloma: results of two phase 1/2 trials.

Journal: Blood 20031001

Title: Dosimetry of high dose skeletal targeted radiotherapy (STR) with 166Ho-DOTMP.

Journal: Cancer biotherapy & radiopharmaceuticals 20030401

Title: High-dose 166Ho-DOTMP in myeloablative treatment of multiple myeloma: pharmacokinetics, biodistribution, and absorbed dose estimation.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021001

Title: 177Lu-labeled cyclic polyaminophosphonates as potential agents for bone pain palliation.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20020801

Title: Synthesis and NMR studies of new DOTP-like lanthanide(III) complexes containing a hydrophobic substituent on one phosphonate side arm.

Journal: Inorganic chemistry 20011217

Title: The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities.

Journal: Inorganic chemistry 20011217

Title: Synthesis, purification and biodistribution of (205)Bi-DOTMP, visualizing bone deposition patterns with autoradiography.

Journal: Nuclear medicine and biology 20010501

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Tags:91987-74-5 Molecular Formula|91987-74-5 MDL|91987-74-5 SMILES|91987-74-5 ((1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl)tetrakis(methylene))tetraphosphonic acid