Title: Novel pleuromutilin derivatives as antibacterial agents: synthesis, biological evaluation and molecular docking studies.
Journal: Bioorganic & medicinal chemistry letters20121001
Title: Design, synthesis, and antibacterial activity of novel pleuromutilin derivatives bearing an amino thiazolyl ring.
Journal: Archiv der Pharmazie20120801
Title: Antimicrobial activity of the novel pleuromutilin antibiotic BC-3781 against organisms responsible for community-acquired respiratory tract infections (CARTIs).
Journal: The Journal of antimicrobial chemotherapy20120501
Title: A click chemistry approach to pleuromutilin derivatives, part 2: conjugates with acyclic nucleosides and their ribosomal binding and antibacterial activity.
Journal: Journal of medicinal chemistry20120308
Title: Pleuromutilin and its derivatives-the lead compounds for novel antibiotics.
Journal: Mini reviews in medicinal chemistry20120101
Title: Are pleuromutilin antibiotics finally fit for human use?
Journal: Annals of the New York Academy of Sciences20111201
Title: A stereoselective, Sm(II)-mediated approach to decorated cis-hydrindanes: synthetic studies on faurinone and pleuromutilin.
Journal: Organic & biomolecular chemistry20110407
Title: A concise synthesis of the molecular framework of pleuromutilin.
Journal: Chemical communications (Cambridge, England)20110207
Title: Small plasmids carrying vga(A) or vga(C) genes mediate resistance to lincosamides, pleuromutilins and streptogramin A antibiotics in methicillin-resistant Staphylococcus aureus ST398 from swine.
Journal: The Journal of antimicrobial chemotherapy20101201
Title: The pleuromutilin antibiotics: a new class for human use.
Journal: Current opinion in investigational drugs (London, England : 2000)20100201
Title: Characterization of pACK4, a mobilizable plasmid from Staphylococcus simulans biovar staphylolyticus.
Journal: Plasmid20091101
Title: Mutilins derivatives: from veterinary to human-used antibiotics.
Journal: Mini reviews in medicinal chemistry20091001
Title: Water-soluble phosphate prodrugs of pleuromutilin analogues with potent in vivo antibacterial activity against Gram-positive pathogens.
Journal: Bioorganic & medicinal chemistry letters20090915
Title: Investigating pleuromutilin-producing Clitopilus species and related basidiomycetes.
Journal: FEMS microbiology letters20090801
Title: Novel pleuromutilin derivatives with excellent antibacterial activity against Staphylococcus aureus.
Journal: Chemical biology & drug design20090601
Title: Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket.
Journal: Molecular microbiology20090301
Title: A scalable synthesis of 2S-hydroxymutilin via a modified Rubottom oxidation.
Journal: The Journal of organic chemistry20090102
Title: Pleuromutilin derivatives having a purine ring. Part 3: synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer.
Journal: Bioorganic & medicinal chemistry letters20090101
Title: Pleuromutilin derivatives having a purine ring. Part 2: influence of the central spacer on the antibacterial activity against Gram-positive pathogens.
Journal: Bioorganic & medicinal chemistry letters20090101
Title: A dialdehyde cyclization cascade: an approach to pleuromutilin.
Journal: Angewandte Chemie (International ed. in English)20090101
Title: A click chemistry approach to pleuromutilin conjugates with nucleosides or acyclic nucleoside derivatives and their binding to the bacterial ribosome.
Journal: Journal of medicinal chemistry20080828
Title: Pleuromutilin derivatives having a purine ring. Part 1: new compounds with promising antibacterial activity against resistant Gram-positive pathogens.
Journal: Bioorganic & medicinal chemistry letters20080615
Title: Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens.
Journal: Journal of medicinal chemistry20080410
Title: Retapamulin: a semisynthetic pleuromutilin compound for topical treatment of skin infections in adults and children.
Journal: Future microbiology20071201
Title: Studies on the later stage of the biosynthesis of pleuromutilin.
Journal: Bioscience, biotechnology, and biochemistry20071201
Title: Cyclopentanone ring-cleaved pleuromutilin derivatives.
Journal: European journal of medicinal chemistry20070101
Title: Activity of retapamulin (SB-275833), a novel pleuromutilin, against selected resistant gram-positive cocci.
Journal: Antimicrobial agents and chemotherapy20060701
Title: Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin.
Journal: Molecular microbiology20041201
Title: Synthesis and activity of a C-8 keto pleuromutilin derivative.
Journal: Bioorganic & medicinal chemistry letters20030519
Title: A concise synthesis of the tricyclic skeleton of pleuromutilin and a new approach to cycloheptenes.
Journal: Organic letters20030206
Title: A flexible strategy for the divergent modification of pleuromutilin.
Journal: Chemical communications (Cambridge, England)20021021
Title: Treatment of resistant mycoplasma infection in immunocompromised patients with a new pleuromutilin antibiotic.
Journal: The Journal of infection20011101
Title: Susceptibility to pleuromutilins in Brachyspira (Serpulina) hyodysenteriae.
Journal: Animal health research reviews20010601
Title: Pleuromutilins. Part 1. The identification of novel mutilin 14-carbamates.
Journal: Bioorganic & medicinal chemistry20010501
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