Name: Name:Bis(4-cyanophenyl)methanol
Brand: AABLOCKS
SKU: AA00HT9F
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00HT9F

Chemical Name: Bis(4-cyanophenyl)methanol

CAS Number: 134521-16-7

Molecular Formula: C15H10N2O

Molecular Weight: 234.2527

MDL Number: MFCD07367966

SMILES: OC(c1ccc(cc1)C#N)c1ccc(cc1)C#N

Properties

Complexity: 322

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 18

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.2

Literature fold

Title: Simultaneous quantitative analysis of letrozole, its carbinol metabolite, and carbinol glucuronide in human plasma by LC-MS/MS.

Journal: Analytical and bioanalytical chemistry20120401

Title: Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes.

Journal: Xenobiotica; the fate of foreign compounds in biological systems20091101

Title: Inhibition of drug metabolizing cytochrome P450s by the aromatase inhibitor drug letrozole and its major oxidative metabolite 4,4'-methanol-bisbenzonitrile in vitro.

Journal: Cancer chemotherapy and pharmacology20091001

Title: Micellar electrokinetic chromatographic screening of letrozole and its metabolite in human urine: validation and robustness/ruggedness evaluation.

Journal: Electrophoresis20080201

Title: Micellar electrokinetic chromatographic study of the separation of an aromatase inhibitor and a tryciclic antidepressant in the breast cancer treatment.

Journal: Analytical chemistry insights20080101

Title: Identification of the aromatase inhibitor letrozole in urine by gas chromatography/mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM20050101

134521-16-7 | Bis(4-cyanophenyl)methanol