Home Indole and Oxindoles 14930-96-2
14930-96-2,MFCD00077704
Catalog No.:AA00HXMM

14930-96-2 | 2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione,6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-,(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-

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Purity
Availability
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Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
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5mg
≥98%
in stock  
$169.00   $118.00
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10mg
≥98%
in stock  
$306.00   $214.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00HXMM
Chemical Name:
2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione,6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-,(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-
CAS Number:
14930-96-2
Molecular Formula:
C29H37NO5
Molecular Weight:
479.6078
MDL Number:
MFCD00077704
SMILES:
C[C@@H]1CCC[C@@H](O)/C=C/C(=O)O[C@@]23[C@@H](/C=C/C1)[C@H](O)C(=C)[C@H]([C@H]3[C@@H](NC2=O)Cc1ccccc1)C
NSC Number:
107658
Properties
Properties
 
BP:
740.6°C at 760 mmHg  
Form:
Solid  
MP:
218-223 °C  
Refractive Index:
1.6290 (estimate)  
Solubility:
ethanol: 20 mg/mL  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
859  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
3.4  

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Journal: Molecular and cellular endocrinology 20080611

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Title: Demecolcine-assisted enucleation of goat oocytes: protocol optimization, mechanism investigation, and application to improve the developmental potential of cloned embryos.

Journal: Cloning and stem cells 20080601

Title: Hypoxic preconditioning up-regulates glucose transport activity and glucose transporter (GLUT1 and GLUT3) gene expression after acute anoxic exposure in the cultured rat hippocampal neurons and astrocytes.

Journal: Brain research 20080523

Title: Effects of different activation protocols on preimplantation development, apoptosis and ploidy of bovine parthenogenetic embryos.

Journal: Animal reproduction science 20080501

Title: Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor.

Journal: Pflugers Archiv : European journal of physiology 20080501

Title: Transferrin uptake in Trypanosoma cruzi is impaired by interference on cytostome-associated cytoskeleton elements and stability of membrane cholesterol, but not by obstruction of clathrin-dependent endocytosis.

Journal: Experimental parasitology 20080501

Title: External calcium facilitates signalling, contractile and secretory mechanisms induced after activation of platelets by collagen.

Journal: Platelets 20080501

Title: Oxidative stress and the genomic regulation of aldosterone-stimulated NHE1 activity in SHR renal proximal tubular cells.

Journal: Molecular and cellular biochemistry 20080301

Title: Mitochondrial behavior during oogenesis in zebrafish: a confocal microscopy analysis.

Journal: Development, growth & differentiation 20080301

Title: Hydrogen peroxide activates calcium influx in human neutrophils.

Journal: Molecular and cellular biochemistry 20080201

Title: Involvement of the cytoskeleton in the effect of PGE2 on ion transport in the rat distal colon.

Journal: Prostaglandins & other lipid mediators 20080201

Title: Action potential generation requires a high sodium channel density in the axon initial segment.

Journal: Nature neuroscience 20080201

Title: Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae.

Journal: Journal of natural products 20080201

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Journal: Journal of endodontics 20080201

Title: Subcellular characterization of glucose uptake in coronary endothelial cells.

Journal: Microvascular research 20080101

Title: Vascular smooth muscle contraction evoked by cell volume modulation: role of the cytoskeleton network.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Adjuvant induced glucose uptake by activated T cells is not correlated with increased survival.

Journal: Advances in experimental medicine and biology 20080101

Title: The micronucleus assay determination of chromosomal level DNA damage.

Journal: Methods in molecular biology (Clifton, N.J.) 20080101

Title: Stretch-activated potassium channels in hypotonically induced blebs of atrial myocytes.

Journal: The Journal of membrane biology 20080101

Title: Chronic ethanol exposure inhibits dopamine release via effects on the presynaptic actin cytoskeleton in PC12 cells.

Journal: Brain research 20071214

Title: p53 response to arsenic exposure in epithelial cells: protein kinase B/Akt involvement.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070901

Title: In vitro evidences for glucosensing capacity and mechanisms in hypothalamus, hindbrain, and Brockmann bodies of rainbow trout.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070901

Title: Can electrons travel through actin microfilaments and generate oxidative stress in retinol treated Sertoli cell?

Journal: Molecular and cellular biochemistry 20070701

Title: Peptide degradation is a critical determinant for cell-penetrating peptide uptake.

Journal: Biochimica et biophysica acta 20070701

Title: Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity.

Journal: The Journal of endocrinology 20070701

Title: Cytoskeleton/stretch-activated ion channel interaction regulates myogenic differentiation of skeletal myoblasts.

Journal: Journal of cellular physiology 20070501

Title: RhoB plays an essential role in CXCR2 sorting decisions.

Journal: Journal of cell science 20070501

Title: Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070415

Title: Leptin secretion is related to glucose-derived lipogenesis in isolated adipocytes.

Journal: International journal of obesity (2005) 20070401

Title: Association of alphaB-crystallin, a small heat shock protein, with actin: role in modulating actin filament dynamics in vivo.

Journal: Journal of molecular biology 20070223

Title: Areca nut extracts reduce the intracellular reactive oxygen species and release of myeloperoxidase by human polymorphonuclear leukocytes.

Journal: Journal of periodontal research 20070201

Title: Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20070122

Title: Cryopreservation of immature and in vitro matured porcine oocytes by solid surface vitrification.

Journal: Theriogenology 20070115

Title: In vitro phagocytosis of collagens by immortalised human retinal Müller cells.

Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20070101

Title: HUVECs from newborns with a strong family history of diabetes show diminished ROS synthesis in the presence of high glucose concentrations.

Journal: Diabetes/metabolism research and reviews 20070101

Title: Inhibitory and enhancing effects of piroxicam on whole blood chemiluminescence.

Journal: Luminescence : the journal of biological and chemical luminescence 20070101

Title: Targeting of TMV movement protein to plasmodesmata requires the actin/ER network: evidence from FRAP.

Journal: Traffic (Copenhagen, Denmark) 20070101

Title: Ascorbate uptake in normal and diabetic rat retina and retinal pigment epithelium.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070101

Title: Effect of different parthenogenetic activation methods on the developmental competence of in vitro matured porcine oocytes.

Journal: Animal biotechnology 20070101

Title: Overcoming MIII arrest from spontaneous activation in cultured rat oocytes.

Journal: Cloning and stem cells 20070101

Title: Pyrus pyrifolia stylar S-RNase induces alterations in the actin cytoskeleton in self-pollen and tubes in vitro.

Journal: Protoplasma 20070101

Title: Phagocytosis of the Lyme disease spirochete, Borrelia burgdorferi, by cells from the ticks, Ixodes scapularis and Dermacentor andersoni, infected with an endosymbiont, Rickettsia peacockii.

Journal: Journal of insect science (Online) 20070101

Title: Spreading of neutrophils: from activation to migration.

Journal: Biophysical journal 20061215

Title: Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid.

Journal: Biochemical and biophysical research communications 20061215

Title: Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation.

Journal: Cancer research 20061215

Title: The effects of apoptotic, deported human placental trophoblast on macrophages: possible consequences for pregnancy.

Journal: Journal of reproductive immunology 20061201

Title: Cytoskeletal asymmetry in Zea mays subsidiary cell mother cells: a monopolar prophase microtubule half-spindle anchors the nucleus to its polar position.

Journal: Cell motility and the cytoskeleton 20061101

Title: Involvement of p38 MAP kinase in not only activation of the phagocyte NADPH oxidase induced by formyl-methionyl-leucyl-phenylalanine but also determination of the extent of the activity.

Journal: Journal of biochemistry 20061101

Title: Evaluation of apigenin using in vitro cytochalasin blocked micronucleus assay.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20061001

Title: Cholesterol loading increases the translocation of ATP synthase beta chain into membrane caveolae in vascular endothelial cells.

Journal: Biochimica et biophysica acta 20061001

Title: Altered K+ fluxes and insulin release in pancreatic islets from omega3 fatty acid-depleted rats.

Journal: Endocrine 20061001

Title: Micronucleus frequency in women with genital Chlamydia Trachomatis infection before and after therapy.

Journal: Mutation research 20060919

Title: Early development of reconstructed embryos after somatic cell nuclear transfer in a non-human primate.

Journal: Theriogenology 20060915

Title: PEI-alginate nanocomposites as efficient in vitro gene transfection agents.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060912

Title: Regulation of the rat brain Na+ -driven Cl-/HCO3 - exchanger involves protein kinase A and a multiprotein signaling complex.

Journal: FEBS letters 20060904

Title: Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060901

Title: SFTG international collaborative study on in vitro micronucleus test IV. Using CHL cells.

Journal: Mutation research 20060804

Title: SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells.

Journal: Mutation research 20060804

Title: SFTG international collaborative study on in vitro micronucleus test I. General conditions and overall conclusions of the study.

Journal: Mutation research 20060804

Title: Development to the blastocyst stage of parthenogenetically activated in vitro matured porcine oocytes after solid surface vitrification (SSV).

Journal: Theriogenology 20060715

Title: Enhanced expression of glucose transporter 1 on erythrocyte membrane in hemodialysis patients: the possible role in erythrocyte ascorbate recycling.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20060601

Title: Characterization of calcium oscillation patterns in caprine oocytes induced by IVF or an activation technique used in nuclear transfer.

Journal: Theriogenology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Protozoan grazing increases mineralization of naphthalene in marine sediment.

Journal: Microbial ecology 20060501

Title: Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN.

Journal: Clinical and vaccine immunology : CVI 20060501

Title: Hypoxia reduces the output of matrix metalloproteinase-9 (MMP-9) in monocytes by inhibiting its secretion and elevating membranal association.

Journal: Journal of leukocyte biology 20060401

Title: Streptococcus pyogenes bacteria modulate membrane traffic in human neutrophils and selectively inhibit azurophilic granule fusion with phagosomes.

Journal: Cellular microbiology 20060401

Title: Improved anti-oxidant activity of superoxide dismutase by direct chemical modification.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20060310

Title: Clustering transmembrane-agrin induces filopodia-like processes on axons and dendrites.

Journal: Molecular and cellular neurosciences 20060301

Title: Protection of TRPC7 cation channels from calcium inhibition by closely associated SERCA pumps.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

Title: Methylene blue stimulates 2-deoxyglucose uptake in L929 fibroblast cells.

Journal: Life sciences 20060102

Title: Multiparametric sensor-chip based technology for monitoring metabolic activity: A proof-of-principle study with live tissue.

Journal: Clinical laboratory 20060101

Title: [Chemical signaling in plant microspore cells].

Journal: Izvestiia Akademii nauk. Seriia biologicheskaia 20060101

Title: Comparison of the relative sensitivity of human lymphocytes and mouse splenocytes to two spindle poisons.

Journal: Mutation research 20051230

Title: Efficient in vitro production of porcine blastocysts by handmade cloning with a combined electrical and chemical activation.

Journal: Theriogenology 20051015

Title: Molecular motors implicated in the axonal transport of tau and alpha-synuclein.

Journal: Journal of cell science 20051015

Title: Dynamic analysis of metabolic effects of chloroacetaldehyde and cytochalasin B on tumor cells using bioelectronic sensor chips.

Journal: Journal of cancer research and clinical oncology 20051001

Title: Aluminium causes variable responses in actin filament cytoskeleton of the root tip cells of Triticum turgidum.

Journal: Protoplasma 20051001

Title: Microtubular integrity differentially modifies the saturated and unsaturated fatty acid metabolism in cultured Hep G2 human hepatoma cells.

Journal: Lipids 20051001

Title: Parthenogenetic activation of mouse oocytes by strontium chloride: a search for the best conditions.

Journal: Theriogenology 20050915

Title: A rapid, direct assay to measure degranulation of primary granules in neutrophils from kidney of fathead minnow (Pimephales promelas Rafinesque, 1820).

Journal: Fish & shellfish immunology 20050901

Title: Importance of cytoskeletal elements in volume regulatory responses of trout hepatocytes.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050901

Title: Modulating the strength of cadherin adhesion: evidence for a novel adhesion complex.

Journal: Journal of cell science 20050901

Title: Extra- and intracellular ice formation in mouse oocytes.

Journal: Cryobiology 20050801

Title: Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.

Journal: Biochemical pharmacology 20050615

Title: Effect of cryopreservation on the cellular integrity of equine embryos.

Journal: Reproduction (Cambridge, England) 20050601

Title: Role of iron in inactivation of epidermal growth factor receptor after asbestos treatment of human lung and pleural target cells.

Journal: American journal of respiratory cell and molecular biology 20050501

Title: Cytoplasmic fragmentation in activated eggs occurs in the cytokinetic phase of the cell cycle, in lieu of normal cytokinesis, and in response to cytoskeletal disorder.

Journal: Molecular human reproduction 20050501

Title: Role of microtubules and centrosomes in the eccentric relocation of the germinal vesicle upon meiosis reinitiation in sea-cucumber oocytes.

Journal: Developmental biology 20050401

Title: Parthenogenetic development of porcine oocytes treated by ethanol, cycloheximide, cytochalasin B and 6-dimethylaminopurine.

Journal: Animal reproduction science 20050401

Title: p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: role in NAD(P)H oxidase regulation by angiotensin II.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050301

Title: Quench-flow analysis reveals multiple phases of GluT1-mediated sugar transport.

Journal: Biochemistry 20050222

Title: RNA interference as a tool to study gene function in bovine oocytes.

Journal: Molecular reproduction and development 20050201

Title: Participation of the ubiquitin-proteasome pathway in rat oocyte activation.

Journal: Zygote (Cambridge, England) 20050201

Title: Micromechanical architecture of the endothelial cell cortex.

Journal: Biophysical journal 20050101

Title: Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways.

Journal: Journal of leukocyte biology 20050101

Title: Peroxynitrite activates glucose uptake in 3T3-L1 adipocytes through a PI3-K-dependent mechanism.

Journal: Frontiers in bioscience : a journal and virtual library 20050101

Title: Role of the actin cytoskeleton in angiotensin II signaling in human vascular smooth muscle cells.

Journal: Canadian journal of physiology and pharmacology 20050101

Title: Substrate preferences and glucose uptake in glibenclamide-resistant Leishmania parasites.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050101

Title: In vitro micronucleus technique to predict chemosensitivity.

Journal: Methods in molecular medicine 20050101

Title: Role of calcium in the secretion of leptin from white adipocytes.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041201

Title: Developmental capacity of vitrified immature porcine oocytes following ICSI: effects of cytochalasin B and cryoprotectants.

Journal: Cryobiology 20041201

Title: The effect of activation protocols on the development of cloned goat embryos.

Journal: The Journal of veterinary medical science 20041201

Title: Effect of actin microfilament on potassium current in guinea pig gastric myocytes.

Journal: World journal of gastroenterology 20041115

Title: Neurofilament transport is dependent on actin and myosin.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041027

Title: Smooth muscle F-actin disassembly and RhoA/Rho-kinase signaling during endotoxin-induced alterations in pulmonary arterial compliance.

Journal: American journal of physiology. Lung cellular and molecular physiology 20041001

Title: Organization and function of microfilaments during late epiboly in zebrafish embryos.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20041001

Title: Fate of the first polar bodies in mouse oocytes.

Journal: Molecular reproduction and development 20040901

Title: Actin is closely associated with RNA polymerase II and involved in activation of gene transcription.

Journal: Biochemical and biophysical research communications 20040827

Title: Altered calcium-induced exocytosis in neutrophils from allergic patients.

Journal: International archives of allergy and immunology 20040801

Title: Facilitated glucose and dehydroascorbate transport in plant mitochondria.

Journal: Archives of biochemistry and biophysics 20040801

Title: Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20040701

Title: The action mechanism of zinc(II) complexes with insulinomimetic activity in rat adipocytes.

Journal: Life sciences 20040625

Title: D-mannose transport and metabolism in isolated enterocytes.

Journal: Glycobiology 20040601

Title: Effect of thrombopoietin alone and a combination of cytochalasin B and ethylene glycol bis(beta-aminoethyl ether) N,N'-tetraacetic acid-AM on the survival and function of autologous baboon platelets stored at 4 degrees C for as long as 5 days.

Journal: Transfusion 20040601

Title: Optimization of parthenogenetic activation protocol in porcine.

Journal: Molecular reproduction and development 20040501

Title: The regulation and importance of glucose uptake in the isolated Atlantic cod heart: rate-limiting steps and effects of hypoxia.

Journal: The Journal of experimental biology 20040501

Title: Human leukocyte elastase and cathepsin G are specific inhibitors of C5a-dependent neutrophil enzyme release and chemotaxis.

Journal: Experimental dermatology 20040501

Title: A new antimalarial quassinoid from Simaba orinocensis.

Journal: Journal of natural products 20040501

Title: Cytoskeletal interactions of synapsin I in non-neuronal cells.

Journal: Biochemical and biophysical research communications 20040423

Title: Ethanol weakens cytochalasin B binding to the GLUT1 glucose transporter and drug partitioning into lipid bilayers.

Journal: Journal of chromatography. A 20040326

Title: Continuous translocation of Rac2 and the NADPH oxidase component p67(phox) during phagocytosis.

Journal: The Journal of biological chemistry 20040305

Title: Effect of a Korean traditional formulation, Hwaotang, on superoxide generation in human neutrophils, platelet aggregation in human blood, and nitric oxide, prostaglandin E2 production and paw oedema induced by carrageenan in mice.

Journal: Immunopharmacology and immunotoxicology 20040201

Title: Activation of equine nuclear transfer oocytes: methods and timing of treatment in relation to nuclear remodeling.

Journal: Biology of reproduction 20040101

Title: Ultrasound contrast agents can influence the respiratory burst activity of human neutrophil granulocytes.

Journal: Ultrasound in medicine & biology 20040101

Title: Actin filaments regulate voltage-gated ion channels in salamander retinal ganglion cells.

Journal: Neuroscience 20040101

Title: Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils.

Journal: BMC cell biology 20040101

Title: Investigations into the biological relevance of in vitro clastogenic and aneugenic activity.

Journal: Cytogenetic and genome research 20040101

Title: Micronuclei in lymphocytes of uranium miners of the former Wismut SDAG.

Journal: Cytogenetic and genome research 20040101

Title: Sodium-dependent transport of [3H](1D)chiro-inositol by Tetrahymena.

Journal: The Journal of eukaryotic microbiology 20040101

Title: Functional consequences of an in vivo mutation in exon 10 of the human GLUT1 gene.

Journal: FEBS letters 20031204

Title: The mechanism of cell death during West Nile virus infection is dependent on initial infectious dose.

Journal: The Journal of general virology 20031201

Title: High-affinity myo-inositol transport in Candida albicans: substrate specificity and pharmacology.

Journal: Microbiology (Reading, England) 20031201

Title: The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV.

Journal: Cell 20031114

Title: Functional cellular assays with multiparametric silicon sensor chips.

Journal: Lab on a chip 20031101

Title: Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils.

Journal: The Journal of biological chemistry 20031003

Title: A simple technique for reducing edge effect in cell-based assays.

Journal: Journal of biomolecular screening 20031001

Title: Hypoxia inactivates inducible nitric oxide synthase in mouse macrophages by disrupting its interaction with alpha-actinin 4.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030915

Title: Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium.

Journal: The Journal of biological chemistry 20030815

Title: Effects of extracellular Ca2+ on phagocytosis and intracellular Ca2+ concentrations in polymorphonuclear leukocytes of postpartum dairy cows.

Journal: Research in veterinary science 20030801

Title: New aspects in pathogenesis of konzo: neural cell damage directly caused by linamarin contained in cassava (Manihot esculenta Crantz).

Journal: The British journal of nutrition 20030801

Title: Glucose transporter proteins (GLUT) in human endometrium: expression, regulation, and function throughout the menstrual cycle and in early pregnancy.

Journal: The Journal of clinical endocrinology and metabolism 20030801

Title: Bimodal acute effects of A1 adenosine receptor activation on Na+/H+ exchanger 3 in opossum kidney cells.

Journal: Journal of the American Society of Nephrology : JASN 20030701

Title: Actin assembly is a crucial factor for superoxide anion generation from adherent human eosinophils.

Journal: The Journal of allergy and clinical immunology 20030701

Title: Outer membrane protein A deficient Escherichia coli activates neutrophils to produce superoxide and shows increased susceptibility to antibacterial peptides.

Journal: Microbes and infection 20030701

Title: Antiparasitic alkaloids from Psychotria klugii.

Journal: Journal of natural products 20030701

Title: Regulation of the mesangial cell myofibroblast phenotype by actin polymerization.

Journal: Journal of cellular physiology 20030601

Title: In vivo imaging of the dynamics of glucose uptake in the cytosol of COS-7 cells by fluorescent nanosensors.

Journal: The Journal of biological chemistry 20030523

Title: Filament formation of MSF-A, a mammalian septin, in human mammary epithelial cells depends on interactions with microtubules.

Journal: The Journal of biological chemistry 20030516

Title: Novel and anti-inflammatory constituents of Garcinia subelliptica.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20030509

Title: Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy.

Journal: Investigative ophthalmology & visual science 20030501

Title: Mechanical stretch-induced apoptosis in smooth muscle cells is mediated by beta1-integrin signaling pathways.

Journal: Hypertension (Dallas, Tex. : 1979) 20030401

Title: The role of actin filaments in the gravitropic response of snapdragon flowering shoots.

Journal: Planta 20030401

Title: Recycling of vitamin C by a bystander effect.

Journal: The Journal of biological chemistry 20030321

Title: Growth cones contain a dynamic population of neurofilament subunits.

Journal: Cell motility and the cytoskeleton 20030301

Title: Effect of nefiracetam, a neurotransmission enhancer, on primary uroepithelial cells of the canine urinary bladder.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030301

Title: Microfilament disruption is required for enucleation and nuclear transfer in germinal vesicle but not metaphase II human oocytes.

Journal: Fertility and sterility 20030301

Title: Accumulation response of chloroplasts induced by mechanical stimulation in bryophyte cells.

Journal: Planta 20030301

Title: Anti-inflammatory constituents and new pterocarpanoid of Crotalaria pallida.

Journal: Journal of natural products 20030301

Title: Randomization of cortical microtubules in root epidermal cells induces root hair initiation in lettuce (Lactuca sativa L.) seedlings.

Journal: Plant & cell physiology 20030301

Title: Centrifugal and chromatographic analyses of tryptophan and tyrosine uptake by red blood cells and GLUT1 proteoliposomes with permeability estimates and observations on dihydrocytochalasin B.

Journal: Journal of biochemical and biophysical methods 20030227

Title: Stage-specific effects of the osmolarity of a culture medium on the development of parthenogenetic diploids in the pig.

Journal: Theriogenology 20030201

Title: Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation.

Journal: Osteoarthritis and cartilage 20030201

Title: Myosin remodelling in the contracting A7r5 smooth muscle cell.

Journal: Acta physiologica Scandinavica 20030201

Title: NADPH-oxidase activation in murine neutrophils via formyl peptide receptors.

Journal: Experimental cell research 20030115

Title: Structure-activity relationship studies on chalcone derivatives. the potent inhibition of chemical mediators release.

Journal: Bioorganic & medicinal chemistry 20030102

Title: Thimerosal induces micronuclei in the cytochalasin B block micronucleus test with human lymphocytes.

Journal: Archives of toxicology 20030101

Title: Görög Thrombosis Test: a global in-vitro test of platelet function and thrombolysis.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20030101

Title: Analysis of insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes.

Journal: Methods in molecular medicine 20030101

Title: [Effects of cycloheximide, aminoglutethimide, indomethacin, cytochalasin B and colchicine on ovulation and the ultrastructure of the ovarian follicle wall in the stellate sturgeon Acipenser stellatus Pall].

Journal: Ontogenez 20030101

Title: Osteopontin traffic in hypoxic renal epithelial cells.

Journal: Nephron. Experimental nephrology 20030101

Title: Matrix metalloproteinase-9 release from human leukocytes.

Journal: Journal of investigational allergology & clinical immunology 20030101

Title: Characterisation of mammalian GLUT glucose transporters in a heterologous yeast expression system.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

Title: Involvement of phosphatidic acid in both degranulation and oxidative activity in fMet-Leu-Phe stimulated polymorphonuclear leukocytes.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101

Title: Effects of glutamate on dehydroascorbate uptake and its enhanced vulnerability to the peroxidation in cerebral cortical slices.

Journal: Experimental & molecular medicine 20021231

Title: Microtubulin configuration and mitochondrial distribution after ultra-rapid cooling of bovine oocytes.

Journal: Molecular reproduction and development 20021201

Title: Characteristics of preimplantational development of porcine parthenogenetic diploids relative to the existence of amino acids in vitro.

Journal: Biology of reproduction 20021201

Title: Hypertonicity-induced projections reflect cell polarity in mouse metaphase II oocytes: involvement of microtubules, microfilaments, and chromosomes.

Journal: Biology of reproduction 20021201

Title: Suppression of apoptosis and clonogenic survival in irradiated human lymphoblasts with different TP53 status.

Journal: Radiation research 20021201

Title: Specific localization of the catalytic subunits of protein kinase CK2 at the centrosomes.

Journal: Cellular and molecular life sciences : CMLS 20021201

Title: Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress.

Journal: Molecular pharmacology 20021101

Title: Theonezolide A, a novel marine macrolide, induces drastic shape change in rabbit platelets by reorganization of microtubules.

Journal: Thrombosis research 20021101

Title: [Contribution of cytoskeleton and integrin to hypergravity response in cultured animal cells].

Journal: Uchu Seibutsu Kagaku 20021101

Title: Pharmacological analysis for mechanisms of GPI-80 release from tumour necrosis factor-alpha-stimulated human neutrophils.

Journal: British journal of pharmacology 20021001

Title: Involvement of calcium signaling and the actin cytoskeleton in the membrane block to polyspermy in mouse eggs.

Journal: Biology of reproduction 20021001

Title: Differences in the regulatory mechanism of amylase release by rat parotid and submandibular glands.

Journal: Archives of oral biology 20021001

Title: Latrunculin and cytochalasin decrease chondrocyte matrix retention.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20021001

Title: Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

Title: Increased neutrophil priming and sensitization before commencing cardiopulmonary bypass in cardiac surgical patients.

Journal: The Annals of thoracic surgery 20021001

Title: Plasmalemmal voltage-activated K(+) currents in protoplasts from tobacco BY-2 cells: possible regulation by actin microfilaments?

Journal: Protoplasma 20021001

Title: Inhibition of in vitro attachment of Giardia trophozoites by mucin.

Journal: The Journal of parasitology 20021001

Title: Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020915

Title: Ascidian otx gene Hroth activates transcription of the brain-specific gene HrTRP.

Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20020901

Title: Relative importance of enhanced glucose uptake versus attenuation of long-chain acyl carnitines in protecting ischemic myocardium.

Journal: Coronary artery disease 20020901

Title: [Effects of different activation methods on in vitro development of bovine somatic cloned embryos].

Journal: Shi yan sheng wu xue bao 20020901

Title: Two parallel pathways mediate cytoplasmic localization of the dioxin (aryl hydrocarbon) receptor.

Journal: The Journal of biological chemistry 20020830

Title: Defensin-rich granules of human neutrophils: characterization of secretory properties.

Journal: Biochimica et biophysica acta 20020819

Title: Interactions of ATP, oestradiol, genistein and the anti-oestrogens, faslodex (ICI 182780) and tamoxifen, with the human erythrocyte glucose transporter, GLUT1.

Journal: The Biochemical journal 20020801

Title: Hyperosmotic stress-induced actin filament reorganization in leaf cells of Chlorophyton comosum.

Journal: Journal of experimental botany 20020801

Title: A modified micropipette aspiration technique and its application to tether formation from human neutrophils.

Journal: Journal of biomechanical engineering 20020801

Title: Hyperosmotic stress induces formation of tubulin macrotubules in root-tip cells of Triticum turgidum: their probable involvement in protoplast volume control.

Journal: Plant & cell physiology 20020801

Title: Cytoskeleton, passive tension and the contraction of the rat aorta to phorbol 12,13-dibutyrate.

Journal: Pharmacological research 20020801

Title: Chronic hyperosmolality enhances ANP-dependent cGMP production via stimulation of transcription and protein synthesis in cultured rat IMCD cells.

Journal: The Tohoku journal of experimental medicine 20020801

Title: Role of formins in actin assembly: nucleation and barbed-end association.

Journal: Science (New York, N.Y.) 20020726

Title: Phosphoinositide 3-kinase mediates protein kinase C beta II mRNA destabilization in rat A10 smooth muscle cell cultures exposed to high glucose.

Journal: Archives of biochemistry and biophysics 20020701

Title: In the polymorphic ciliate Tetrahymena vorax, the non-selective phagocytosis seen in microstomes changes to a highly selective process in macrostomes.

Journal: The Journal of experimental biology 20020701

Title: Phorbol myristate acetate induces ruffling of the acrosome of human sperm.

Journal: Fertility and sterility 20020701

Title: Nicotinamide is not a substrate of the facilitative hexose transporter GLUT1.

Journal: Biochemistry 20020625

Title: Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615

Title: Recycling processes of cellular ascorbate generate oxidative stress in pancreatic tissues in in vitro system.

Journal: Endocrine 20020601

Title: Insulinotropic action of amino acids at their physiological concentrations: I. Experiments in incubated islets.

Journal: International journal of molecular medicine 20020501

Title: The effect of 835.62 MHz FDMA or 847.74 MHz CDMA modulated radiofrequency radiation on the induction of micronuclei in C3H 10T(1/2) cells.

Journal: Radiation research 20020501

Title: Clostridium difficile toxin A alters in vitro-adherent neutrophil morphology and function.

Journal: The Journal of infectious diseases 20020501

Title: Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues.

Journal: Molecular genetics and metabolism 20020501

Title: Induction of micronuclei by alkaloids extracted from Senecio brasiliensis and stored for 23 years.

Journal: Mutation research 20020426

Title: Gap junctions assemble in the presence of cytoskeletal inhibitors, but enhanced assembly requires microtubules.

Journal: Experimental cell research 20020415

Title: Calyculin A-induced endothelial cell shape changes are independent of [Ca(2+)](i) elevation and may involve actin polymerization.

Journal: Biochimica et biophysica acta 20020403

Title: Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway.

Journal: American journal of physiology. Endocrinology and metabolism 20020401

Title: Signaling to localized degranulation in neutrophils adherent to immune complexes.

Journal: Journal of leukocyte biology 20020401

Title: Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells.

Journal: FEBS letters 20020313

Title: Somatic cell nuclear transfer in the pig: control of pronuclear formation and integration with improved methods for activation and maintenance of pregnancy.

Journal: Biology of reproduction 20020301

Title: Activity modes and modulation of the peptide-gated Na(+) channel of Helix neurones.

Journal: Pflugers Archiv : European journal of physiology 20020301

Title: Transient expression of fluorescent tau proteins promotes process formation in PC12 cells: contributions of the tau C-terminus to this process.

Journal: Journal of neuroscience research 20020301

Title: Kinetics of erythrocyte swelling and membrane hole formation in hypotonic media.

Journal: Biochimica et biophysica acta 20020201

Title: Effects of cytochalasin B and D upon insulin release and pancreatic islet cell metabolism.

Journal: International journal of molecular medicine 20020201

Title: P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.

Journal: American journal of physiology. Renal physiology 20020101

Title: An anti-actin monoclonal antibody inhibits the zona pellucida-induced acrosome reaction and hyperactivated motility of human sperm.

Journal: Molecular human reproduction 20020101

Title: Pressure-induced actin polymerization in vascular smooth muscle as a mechanism underlying myogenic behavior.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101

Title: Inhibition of cytoskeletal assembly by cytochalasin B prevents signaling through tyrosine phosphorylation and secretion triggered by collagen but not by thrombin.

Journal: The American journal of pathology 20020101

Title: A neutrophil multitarget functional bioassay to detect anti-inflammatory natural products.

Journal: Journal of natural products 20020101

Title: Chemiluminescent detection of induced reactive oxygen metabolite production of human polymorphonuclear leucocytes by anthophyllite asbestos.

Journal: Environmental research 20020101

Title: The N-formylpeptide receptor (FPR) and a second G(i)-coupled receptor mediate fMet-Leu-Phe-stimulated activation of NADPH oxidase in murine neutrophils.

Journal: Cellular immunology 20020101

Title: Involvement of protein tyrosine kinases and phosphatases in uptake and intracellular replication of virulent and avirulent Leishmania donovani promastigotes in mouse macrophage cells.

Journal: Bioscience reports 20020101

Title: The red blood cell glucose transporter presents multiple, nucleotide-sensitive sugar exit sites.

Journal: Biochemistry 20011225

Title: Hepatic and extrahepatic factors critical for liver injury during lipopolysaccharide exposure.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20011201

Title: Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011201

Title: Diverse effects of cytochalasin B on priming and triggering the respiratory burst activity in human neutrophils and monocytes.

Journal: International journal of hematology 20011201

Title: The redistribution of Ca2+ stores with inositol 1,4,5-trisphosphate receptor to the cleavage furrow in a microtubule-dependent manner.

Journal: The International journal of developmental biology 20011201

Title: The photoprotein pholasin as a luminescence substrate for detection of superoxide anion radicals and myeloperoxidase activity in stimulated neutrophils.

Journal: Free radical research 20011201

Title: Mechanism of vitamin C inhibition of cell death induced by oxidative stress in glutathione-depleted HL-60 cells.

Journal: The Journal of biological chemistry 20011102

Title: Evaluation of apoptosis and micronucleation induced by reactor neutron beams with two different cadmium ratios in total and quiescent cell populations within solid tumors.

Journal: International journal of radiation oncology, biology, physics 20011101

Title: Glucose transport and apoptosis after gene therapy with HSV thymidine kinase.

Journal: European journal of nuclear medicine 20011101

Title: Characterization of D-fructose transport by rat kidney brush-border membrane vesicles: changes in hypertensive rats.

Journal: Cellular and molecular life sciences : CMLS 20011101

Title: Reorganization of actin during repair of hair bundle mechanoreceptors.

Journal: Journal of neurocytology 20011101

Title: Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle.

Journal: The Biochemical journal 20011015

Title: Cytoskeleton elements mediate the inhibition of the (Na++K+)atpase activity by PKC in Rhodnius prolixus malpighian tubules during hyperosmotic shock.

Journal: Archives of insect biochemistry and physiology 20011001

Title: Phosphatidylinositol 3-kinase and ERK are required for NF-kappaB activation but not for phagocytosis.

Journal: Journal of leukocyte biology 20011001

Title: Release of cysteinyl leukotrienes with aspirin stimulation and the effect of prostaglandin E(2) on this release from peripheral blood leucocytes in aspirin-induced asthmatic patients.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20011001

Title: An actin barrier to resealing.

Journal: Journal of cell science 20011001

Title: Concentration-dependent phorbol stimulation of PKCalpha localization at the nucleus or subplasmalemma in A7r5 cells.

Journal: Pflugers Archiv : European journal of physiology 20011001

Title: Cytoskeleton-interacting activity of geiparvarin, diethylstilbestrol and conjugates.

Journal: Chemico-biological interactions 20010928

Title: Pancreatic fate of D-[3H] mannoheptulose.

Journal: Cell biochemistry and function 20010901

Title: Evaluation of the potential of p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, referring to the effect on intratumor quiescent cells.

Journal: Japanese journal of cancer research : Gann 20010901

Title: Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation.

Journal: Biochimica et biophysica acta 20010815

Title: Aldosterone mediates the changes in hexose transport induced by low sodium intake in chicken distal intestine.

Journal: The Journal of physiology 20010815

Title: Assessment of islet beta-cell mass in isolated rat pancreases perfused with D-[(3)H]mannoheptulose.

Journal: American journal of physiology. Endocrinology and metabolism 20010801

Title: Vitamin C transport in human lens epithelial cells: evidence for the presence of SVCT2.

Journal: Experimental eye research 20010801

Title: Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20010801

Title: Changes in the mechanical and adhesive behaviour of human neutrophils on cooling in vitro.

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Tags:14930-96-2 Molecular Formula|14930-96-2 MDL|14930-96-2 SMILES|14930-96-2 2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione,6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-,(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-