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18507-89-6,MFCD00673686
Catalog No.:AA00I1GG

18507-89-6 | ethyl 6-(decyloxy)-7-ethoxy-4-hydroxyquinoline-3-carboxylate

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1g
97%
in stock  
$29.00   $20.00
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5g
97%
in stock  
$37.00   $26.00
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25g
98%
in stock  
$44.00   $31.00
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500g
98%
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$501.00   $351.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I1GG
Chemical Name:
ethyl 6-(decyloxy)-7-ethoxy-4-hydroxyquinoline-3-carboxylate
CAS Number:
18507-89-6
Molecular Formula:
C24H35NO5
Molecular Weight:
417.5384
MDL Number:
MFCD00673686
SMILES:
CCCCCCCCCCOc1cc2c(cc1OCC)ncc(c2O)C(=O)OCC
Properties
Computed Properties
 
Complexity:
562  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
15  
XLogP3:
6.8  

Literature

Title: Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice.

Journal: Nanomedicine : nanotechnology, biology, and medicine 20140101

Title: The history of decoquinate in the control of coccidial infections in ruminants.

Journal: Journal of veterinary pharmacology and therapeutics 20121001

Title: Detection and quantitative analysis of 21 veterinary drugs in river water using high-pressure liquid chromatography coupled to tandem mass spectrometry.

Journal: Environmental science and pollution research international 20120901

Title: In vitro determination of anticryptosporidial activity of phytogenic extracts and compounds.

Journal: Parasitology research 20120701

Title: Effects of kefir on coccidial oocysts excretion and performance of dairy goat kids following weaning.

Journal: Tropical animal health and production 20120601

Title: Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug.

Journal: The Journal of infectious diseases 20120415

Title: Medicating feeds for early lambing ewes.

Journal: The Veterinary record 20120211

Title: Use of coccidiostat in mineral salt and study on ovine eimeriosis.

Journal: Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20120101

Title: A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor.

Journal: ACS chemical biology 20111118

Title: Lower prevalence of antibiotic-resistant Enterococci on U.S. conventional poultry farms that transitioned to organic practices.

Journal: Environmental health perspectives 20111101

Title: Perspectives on canine and feline hepatozoonosis.

Journal: Veterinary parasitology 20110908

Title: Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.

Journal: Analytica chimica acta 20110826

Title: Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.

Journal: Analytica chimica acta 20110826

Title: The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites.

Journal: Avian diseases 20110301

Title: Severe myositis associated with Sarcocystis spp. infection in 2 dogs.

Journal: Journal of veterinary internal medicine 20110101

Title: Efficacy of amprolium and toltrazuril in chicken with subclinical infection of cecal coccidiosis.

Journal: Indian journal of pharmacology 20110101

Title: Multi-residue method for detecting coccidiostats at carry-over level in feed by HPLC-MS/MS.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20100601

Title: Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: Oral pharmacokinetics and milk residues of decoquinate in milking cows.

Journal: Journal of veterinary pharmacology and therapeutics 20090801

Title: Supply of Deccox 25 Individual Treatment Packs.

Journal: The Veterinary record 20090321

Title: Use of GenMAPP and MAPPFinder to analyse pathways involved in chickens infected with the protozoan parasite Eimeria.

Journal: BMC proceedings 20090101

Title: Giardia duodenalis in feedlot cattle from the central and western United States.

Journal: BMC veterinary research 20090101

Title: Determination of decoquinate in animal feeds by liquid chromatography: collaborative study.

Journal: Journal of AOAC International 20080101

Title: Ovine toxoplasmosis: transmission, clinical outcome and control.

Journal: Parassitologia 20071201

Title: Efficacy of decoquinate against drug sensitive laboratory strains of Eimeria tenella and field isolates of Eimeria spp. in broiler chickens in China.

Journal: Veterinary parasitology 20070720

Title: Effect of the quinolone coccidiostat decoquinate on the rearrangement of chromosomes of Eimeria tenella.

Journal: International journal for parasitology 20061201

Title: Field study of the efficacy of halofuginone and decoquinate in the treatment of cryptosporidiosis in veal calves.

Journal: The Veterinary record 20061111

Title: Tracing the emergence of drug-resistance in coccidia (Eimeria spp.) of commercial broiler flocks medicated with decoquinate for the first time in the United Kingdom.

Journal: Veterinary parasitology 20060115

Title: Relative virulences of a drug-resistant and a drug-sensitive strain of Eimeria acervulina, a coccidium of chickens.

Journal: Veterinary parasitology 20060115

Title: An Irish perspective on Cryptosporidium. Part 2.

Journal: Irish veterinary journal 20060101

Title: Effect of different decoquinate treatments on cryptosporidiosis in naturally infected cashmere goat kids.

Journal: The Veterinary record 20050827

Title: Questions limitation in treatment of hepatozoonosis.

Journal: Journal of the American Veterinary Medical Association 20050615

Title: Prophylactic use of decoquinate for infections with Cryptosporidium parvum in experimentally challenged neonatal calves.

Journal: Journal of the American Veterinary Medical Association 20030915

Title: Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss.

Journal: Diseases of aquatic organisms 20030620

Title: Treatment of dogs infected with Hepatozoon americanum: 53 cases (1989-1998).

Journal: Journal of the American Veterinary Medical Association 20010101

Title: Activity of decoquinate against Cryptosporidium parvum in cell cultures and neonatal mice.

Journal: Veterinary parasitology 20000517

Title: Decoquinate induces tissue cyst formation by the RH strain of Toxoplasma gondii.

Journal: Veterinary parasitology 19980615

Title: Mutants of Toxoplasma gondii resistant to atovaquone (566C80) or decoquinate.

Journal: The Journal of parasitology 19930801

Title: In vivo expression of in vitro anticoccidial activity.

Journal: Antimicrobial agents and chemotherapy 19921001

Title: Wang H, et al. Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice. Nanomedicine. 2014 Jan;10(1):57-65.

Title: Beteck RM, et al. Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities. Bioorg Med Chem Lett. 2016 Jul 1;26(13):3006-3009.

Title: Taylor MA, et, al. The history of decoquinate in the control of coccidial infections in ruminants. J Vet Pharmacol Ther. 2012 Oct;35(5):417-27.

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