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20350-15-6,MFCD12913297
Catalog No.:AA00I3R7

20350-15-6 | Brefeldin a

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1mg
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5mg
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I3R7
Chemical Name:
Brefeldin a
CAS Number:
20350-15-6
Molecular Formula:
C16H24O4
Molecular Weight:
280.3594
MDL Number:
MFCD12913297
SMILES:
O[C@@H]1C[C@@H]2C(C1)/C=C/CCC[C@@H](OC(=O)/C=C/[C@H]2O)C C16H24O4
Properties
Computed Properties
 
Complexity:
388  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
XLogP3:
2  

Downstream Synthesis Route

[1]EuropeanJournalofOrganicChemistry,2011,p.878-891

[2]JournaloftheAmericanChemicalSociety,1991,vol.113,p.6639-6645

[1]NatureChemistry,2017,vol.9,p.1213-1221

[2]Pharmazie,1992,vol.47,p.582-584

[3]BioorganicandMedicinalChemistryLetters,1997,vol.7,p.139-144

[1]JournaloftheChemicalSociety.PerkintransactionsI,1994,p.3431-3440

[2]JournaloftheAmericanChemicalSociety,1991,vol.113,p.6639-6645

(-)-(2E,4S,5R,7S,9S,10E,15S)-4-<(p-Methoxybenzyl)oxy>-7-<(2-methoxyethoxy)methoxy>brefeldin 
  20350-15-6 

[1]JournalofOrganicChemistry,1993,vol.58,p.4555-4563

(5E,13E)-(2S,3aR,4R,9S,14aS)-2,4-Bis-methoxymethoxy-9-methyl-1,2,3,3a,4,9,10,11,12,14a-decahydro-8-oxa-cyclopentacyclotridecen-7-one 
  20350-15-6 

[1]JournaloftheChemicalSociety.Chemicalcommunications,1994,p.1085-1086

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Title: Inhibition of heparan sulfate and chondroitin sulfate proteoglycan biosynthesis.

Journal: The Journal of biological chemistry 20081024

Title: Brefeldin A inhibits cholesterol efflux without affecting the rate of cellular uptake and re-secretion of apolipoprotein A-I in adipocytes.

Journal: Archives of biochemistry and biophysics 20081015

Title: The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network.

Journal: The Biochemical journal 20080915

Title: Palmitoylation and membrane interactions of the neuroprotective chaperone cysteine-string protein.

Journal: The Journal of biological chemistry 20080905

Title: Similarities between UDP-glucose and adenine nucleotide release in yeast: involvement of the secretory pathway.

Journal: Biochemistry 20080902

Title: Sucrose synthase is associated with the cell wall of tobacco pollen tubes.

Journal: Plant physiology 20080801

Title: Interstitial adenosine triphosphate modulates muscle afferent nerve-mediated pressor reflex.

Journal: Muscle & nerve 20080801

Title: Molecular mechanism underlying the association of Coronin-7 with Golgi membranes.

Journal: Cellular and molecular life sciences : CMLS 20080801

Title: Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells.

Journal: Molecular cancer therapeutics 20080801

Title: Glutamatergic cerebellar granule neurons synthesize and secrete reelin in vitro.

Journal: Neuron glia biology 20080801

Title: Polychromatic flow cytometric high-throughput assay to analyze the innate immune response to Toll-like receptor stimulation.

Journal: Journal of immunological methods 20080731

Title: Proteolytic processing of cGMP-dependent protein kinase I mediates nuclear cGMP signaling in vascular smooth muscle cells.

Journal: Circulation research 20080703

Title: Rho-family GTPases modulate Ca(2+) -dependent ATP release from astrocytes.

Journal: American journal of physiology. Cell physiology 20080701

Title: Insulin regulates leptin secretion from 3T3-L1 adipocytes by a PI 3 kinase independent mechanism.

Journal: Experimental cell research 20080701

Title: Kaempferol and quercetin stimulate granulocyte-macrophage colony-stimulating factor secretion in human prostate cancer cells.

Journal: Molecular and cellular endocrinology 20080611

Title: Rescue of mutant alpha-galactosidase A in the endoplasmic reticulum by 1-deoxygalactonojirimycin leads to trafficking to lysosomes.

Journal: Biochimica et biophysica acta 20080601

Title: Biosynthesis, processing, trafficking, and enzymatic activity of mouse neprilysin 2.

Journal: Molecular and cellular biochemistry 20080601

Title: Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation.

Journal: PLoS pathogens 20080601

Title: Wheat germ agglutinin stains dispersed post-golgi vesicles after treatment with the cytokinesis inhibitor psychosine.

Journal: Journal of cellular physiology 20080501

Title: Adaptor protein Ruk/CIN85 is associated with a subset of COPI-coated membranes of the Golgi complex.

Journal: Traffic (Copenhagen, Denmark) 20080501

Title: Slower rescue of ER homeostasis by the unfolded protein response pathway associated with common variable immunodeficiency.

Journal: Molecular immunology 20080501

Title: Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells.

Journal: European journal of immunology 20080501

Title: Rapid tip-directed movement of Golgi equivalents in growing Aspergillus nidulans hyphae suggests a mechanism for delivery of growth-related materials.

Journal: Microbiology (Reading, England) 20080501

Title: Dual fatty acyl modification determines the localization and plasma membrane targeting of CBL/CIPK Ca2+ signaling complexes in Arabidopsis.

Journal: The Plant cell 20080501

Title: Proteasome-dependent pharmacological rescue of cystic fibrosis transmembrane conductance regulator revealed by mutation of glycine 622.

Journal: The Journal of pharmacology and experimental therapeutics 20080401

Title: Tripeptidyl peptidase II is dispensable for the generation of both proteasome-dependent and proteasome-independent ligands of HLA-B27 and other class I molecules.

Journal: European journal of immunology 20080301

Title: Antineoplastic agents. 536. New sources of naturally occurring cancer cell growth inhibitors from marine organisms, terrestrial plants, and microorganisms(1a,).

Journal: Journal of natural products 20080301

Title: Identification of a novel p53-dependent activation pathway of STAT1 by antitumour genotoxic agents.

Journal: Cell death and differentiation 20080201

Title: dGRASP-mediated noncanonical integrin secretion is required for Drosophila epithelial remodeling.

Journal: Developmental cell 20080201

Title: Unstimulated amylase secretion is proteoglycan-dependent in rat parotid acinar cells.

Journal: Archives of biochemistry and biophysics 20080115

Title: The GRV2/RME-8 protein of Arabidopsis functions in the late endocytic pathway and is required for vacuolar membrane flow.

Journal: The Plant journal : for cell and molecular biology 20080101

Title: Acute effectors of GLUT1 glucose transporter subcellular targeting in CIT3 mouse mammary epithelial cells.

Journal: Pediatric research 20080101

Title: Endocytosis inhibitors prevent poly(amidoamine) dendrimer internalization and permeability across Caco-2 cells.

Journal: Molecular pharmaceutics 20080101

Title: Different subcellular localizations and functions of Arabidopsis myosin VIII.

Journal: BMC plant biology 20080101

Title: Calcium-dependent proapoptotic effect of Taenia solium metacestodes annexin B1 on human eosinophils: a novel strategy to prevent host immune response.

Journal: The international journal of biochemistry & cell biology 20080101

Title: Effect of brefeldin A on membrane localization of MUC1 mucin and adhesive properties of cancer cells.

Journal: Neoplasma 20080101

Title: Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

Journal: Reproductive biology and endocrinology : RB&E 20080101

Title: RET(MEN 2B) is active in the endoplasmic reticulum before reaching the cell surface.

Journal: Oncogene 20071213

Title: Brefeldin A triggers apoptosis associated with mitochondrial breach and enhances HA14-1- and anti-Fas-mediated cell killing in follicular lymphoma cells.

Journal: Leukemia research 20071201

Title: A trafficking pathway for anthocyanins overlaps with the endoplasmic reticulum-to-vacuole protein-sorting route in Arabidopsis and contributes to the formation of vacuolar inclusions.

Journal: Plant physiology 20071201

Title: P-glycoprotein4 displays auxin efflux transporter-like action in Arabidopsis root hair cells and tobacco cells.

Journal: The Plant cell 20071201

Title: Modulation of epithelial sodium channel trafficking and function by sodium 4-phenylbutyrate in human nasal epithelial cells.

Journal: The Journal of biological chemistry 20071123

Title: IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis.

Journal: Cell 20071116

Title: A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells.

Journal: The Journal of pharmacology and experimental therapeutics 20071101

Title: CEL-I, an invertebrate N-acetylgalactosamine-specific C-type lectin, induces TNF-alpha and G-CSF production by mouse macrophage cell line RAW264.7 cells.

Journal: Journal of biochemistry 20071101

Title: Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.

Journal: Traffic (Copenhagen, Denmark) 20071101

Title: Glycosylation modulates TRAIL-R1/death receptor 4 protein: different regulations of two pro-apoptotic receptors for TRAIL by tunicamycin.

Journal: Oncology reports 20071101

Title: Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via an alternate class I MHC processing pathway.

Journal: Archives of pharmacal research 20071101

Title: Transcriptional profiling of genes that are regulated by the endoplasmic reticulum-bound transcription factor AIbZIP/CREB3L4 in prostate cells.

Journal: Physiological genomics 20071022

Title: Simultaneous arming and structure/activity studies of natural products employing O-H insertions: an expedient and versatile strategy for natural products-based chemical genetics.

Journal: Journal of the American Chemical Society 20071010

Title: Aldosterone-induced modification of osmoregulated ENaC trafficking.

Journal: Biochemical and biophysical research communications 20070914

Title: Rab11B small GTPase regulates secretion of cysteine proteases in the enteric protozoan parasite Entamoeba histolytica.

Journal: Cellular microbiology 20070901

Title: H-Ras does not need COP I- or COP II-dependent vesicular transport to reach the plasma membrane.

Journal: The Journal of biological chemistry 20070831

Title: Lateral diffusion of the GABAB receptor is regulated by the GABAB2 C terminus.

Journal: The Journal of biological chemistry 20070831

Title: Flow cytometric detection of degranulation reveals phenotypic heterogeneity of degranulating CMV-specific CD8+ T lymphocytes in rhesus macaques.

Journal: Journal of immunological methods 20070831

Title: Opioid receptor pharmacological chaperones act by binding and stabilizing newly synthesized receptors in the endoplasmic reticulum.

Journal: The Journal of biological chemistry 20070810

Title: Stimulation of lipolysis enhances the rate of cholesterol efflux to HDL in adipocytes.

Journal: Molecular and cellular biochemistry 20070801

Title: Membrane cytosolic translocation of verotoxin A1 subunit in target cells.

Journal: Microbiology (Reading, England) 20070801

Title: Visfatin is released from 3T3-L1 adipocytes via a non-classical pathway.

Journal: Biochemical and biophysical research communications 20070727

Title: Ca2+ dependence of flow-stimulated K secretion in the mammalian cortical collecting duct.

Journal: American journal of physiology. Renal physiology 20070701

Title: Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20070619

Title: Nuclear membrane disassembly and rupture.

Journal: Journal of molecular biology 20070608

Title: HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway.

Journal: American journal of physiology. Heart and circulatory physiology 20070601

Title: Plasma membrane delivery, endocytosis and turnover of transcobalamin receptor in polarized human intestinal epithelial cells.

Journal: The Journal of physiology 20070601

Title: Molecular and clinical characterization of a Moroccan Cog7 deficient patient.

Journal: Molecular genetics and metabolism 20070601

Title: Endoplasmic reticulum stress-induced cell death mediated by the proteasome.

Journal: Cell death and differentiation 20070601

Title: Membrane trafficking of CD98 and its ligand galectin 3 in BeWo cells--implication for placental cell fusion.

Journal: The FEBS journal 20070601

Title: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor.

Journal: The FEBS journal 20070601

Title: Non-neuronal acetylcholine and urinary bladder urothelium.

Journal: Life sciences 20070530

Title: Regulation of heparan sulfate 6-O-sulfation by beta-secretase activity.

Journal: The Journal of biological chemistry 20070518

Title: Copper-transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer.

Journal: Cancer research 20070515

Title: Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol.

Journal: Traffic (Copenhagen, Denmark) 20070501

Title: The role of cargo proteins in GGA recruitment.

Journal: Traffic (Copenhagen, Denmark) 20070501

Title: Diverse subcellular locations of cryptogein-induced reactive oxygen species production in tobacco Bright Yellow-2 cells.

Journal: Plant physiology 20070401

Title: FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation.

Journal: Biochimica et biophysica acta 20070401

Title: Comprehensive phenotypic analysis of the gut intra-epithelial lymphocyte compartment: perturbations induced by acute reovirus 1/L infection of the gastrointestinal tract.

Journal: International immunology 20070401

Title: An altered peptide ligand for naïve cytotoxic T lymphocyte epitope of TRP-2(180-188) enhanced immunogenicity.

Journal: Cancer immunology, immunotherapy : CII 20070301

Title: Brain-type creatine kinase BB-CK interacts with the Golgi Matrix Protein GM130 in early prophase.

Journal: Molecular and cellular biochemistry 20070301

Title: Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.

Journal: Journal of biochemistry 20070301

Title: TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.

Journal: Hepatology (Baltimore, Md.) 20070301

Title: Endoplasmic reticulum stress and the unfolded protein response regulate genomic cystic fibrosis transmembrane conductance regulator expression.

Journal: American journal of physiology. Cell physiology 20070201

Title: Brefeldin A or monensin inhibits the 3D organizer in gastropod, polyplacophoran, and scaphopod molluscs.

Journal: Development genes and evolution 20070201

Title: Role of p53 in neurotoxicity induced by the endoplasmic reticulum stress agent tunicamycin in organotypic slice cultures of rat spinal cord.

Journal: Journal of neuroscience research 20070201

Title: [Internalizing to control , or how endocytosis regulates auxin flux in plants].

Journal: Medecine sciences : M/S 20070201

Title: Up-regulation of skeletal muscle LIM protein 1 gene by 25-hydroxycholesterol may mediate morphological changes of rat aortic smooth muscle cells.

Journal: Life sciences 20070109

Title: Developmental acquisition of T3-sensitive Na-K-ATPase stimulation by rat alveolar epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20070101

Title: Extensive proteolytic processing of the malaria parasite merozoite surface protein 7 during biosynthesis and parasite release from erythrocytes.

Journal: Molecular and biochemical parasitology 20070101

Title: Targeting of TMV movement protein to plasmodesmata requires the actin/ER network: evidence from FRAP.

Journal: Traffic (Copenhagen, Denmark) 20070101

Title: Rice SCAMP1 defines clathrin-coated, trans-golgi-located tubular-vesicular structures as an early endosome in tobacco BY-2 cells.

Journal: The Plant cell 20070101

Title: Arabidopsis PLDzeta2 regulates vesicle trafficking and is required for auxin response.

Journal: The Plant cell 20070101

Title: Quaternary structure and apical membrane sorting of the mammalian NaSi-1 sulfate transporter in renal cell lines.

Journal: The international journal of biochemistry & cell biology 20070101

Title: Brefeldin A and monensin inhibit the D quadrant organizer in the polychaete annelids Arctonoe vittata and Serpula columbiana.

Journal: Evolution & development 20070101

Title: Differential association between HERG and KCNE1 or KCNE2.

Journal: PloS one 20070101

Title: 1-Butanol targets the Golgi apparatus in tobacco BY-2 cells, but in a different way to Brefeldin A.

Journal: Journal of experimental botany 20070101

Title: Amino acid transporter ATA2 is stored at the trans-Golgi network and released by insulin stimulus in adipocytes.

Journal: The Journal of biological chemistry 20061222

Title: Different endoplasmic reticulum trafficking and processing pathways for calsequestrin (CSQ) and epitope-tagged CSQ.

Journal: Experimental cell research 20061210

Title: RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1.

Journal: American journal of physiology. Renal physiology 20061201

Title: Transporter regulator RS1 (RSC1A1) coats the trans-Golgi network and migrates into the nucleus.

Journal: American journal of physiology. Renal physiology 20061201

Title: Sorting nexin 10 induces giant vacuoles in mammalian cells.

Journal: The Journal of biological chemistry 20061201

Title: A conserved subtilisin protease identified in Babesia divergens merozoites.

Journal: The Journal of biological chemistry 20061124

Title: Amyloid beta peptide as a physiological modulator of neuronal 'A'-type K+ current.

Journal: Neurobiology of aging 20061101

Title: Ligands regulate cell surface level of the human kappa opioid receptor by activation-induced down-regulation and pharmacological chaperone-mediated enhancement: differential effects of nonpeptide and peptide agonists.

Journal: The Journal of pharmacology and experimental therapeutics 20061101

Title: Plant N-glycan processing enzymes employ different targeting mechanisms for their spatial arrangement along the secretory pathway.

Journal: The Plant cell 20061101

Title: Modulation of GalT1 and SialT1 sub-Golgi localization by SialT2 expression reveals an organellar level of glycolipid synthesis control.

Journal: The Journal of biological chemistry 20061027

Title: Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein.

Journal: Experimental cell research 20061001

Title: GBF1, a cis-Golgi and VTCs-localized ARF-GEF, is implicated in ER-to-Golgi protein traffic.

Journal: Journal of cell science 20060915

Title: Mechanism underlying flow stimulation of sodium absorption in the mammalian collecting duct.

Journal: American journal of physiology. Renal physiology 20060901

Title: Architecture of the vimentin cytoskeleton is modified by perturbation of the GTPase ARF1.

Journal: Journal of cell science 20060901

Title: Evidence for serum-deprivation-induced co-release of FGF-1 and S100A13 from astrocytes.

Journal: Neurochemistry international 20060801

Title: Localization of Golgi 58K protein (formiminotransferase cyclodeaminase) to the centrosome.

Journal: Histochemistry and cell biology 20060801

Title: Open probability of the epithelial sodium channel is regulated by intracellular sodium.

Journal: The Journal of physiology 20060715

Title: Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs.

Journal: Experimental cell research 20060715

Title: CaMKII-independent effects of KN93 and its inactive analog KN92: reversible inhibition of L-type calcium channels.

Journal: Biochemical and biophysical research communications 20060714

Title: Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling.

Journal: Neuron 20060706

Title: Neuregulin isoforms in dorsal root ganglion neurons: effects of the cytoplasmic domain on localization and membrane shedding of Nrg-1 type I.

Journal: Journal of neuroscience research 20060701

Title: Activation of kinin B1 receptors induces chemotaxis of human neutrophils.

Journal: Journal of leukocyte biology 20060701

Title: PINOID positively regulates auxin efflux in Arabidopsis root hair cells and tobacco cells.

Journal: The Plant cell 20060701

Title: Intracellular pathways of folded and misfolded amyloid precursor protein degradation.

Journal: Archives of biochemistry and biophysics 20060701

Title: Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20060701

Title: Intracellular trafficking of recycling apolipoprotein E in Chinese hamster ovary cells.

Journal: Journal of lipid research 20060601

Title: Airway inflammation in asymptomatic children with episodic wheeze.

Journal: Pediatric pulmonology 20060601

Title: A phosphatidylinositol-3-kinase-dependent signal transition regulates ARF1 and ARF6 during Fcgamma receptor-mediated phagocytosis.

Journal: PLoS biology 20060601

Title: Cloning and recombinant expression of active full-length xylosyltransferase I (XT-I) and characterization of subcellular localization of XT-I and XT-II.

Journal: The Journal of biological chemistry 20060519

Title: STI571 (Glivec) induces cell death in the gastrointestinal stromal tumor cell line, GIST-T1, via endoplasmic reticulum stress response.

Journal: International journal of molecular medicine 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Attachment and fusion of endoplasmic reticulum with vacuoles containing Legionella pneumophila.

Journal: Cellular microbiology 20060501

Title: Multiple vacuolar sorting determinants exist in soybean 11S globulin.

Journal: The Plant cell 20060501

Title: Involvement of yeast YOL151W/GRE2 in ergosterol metabolism.

Journal: Yeast (Chichester, England) 20060415

Title: Ricin induces IL-8 secretion from human monocyte/macrophages by activating the p38 MAP kinase pathway.

Journal: Molecular immunology 20060401

Title: The plasma membrane recycling pathway and cell polarity in plants: studies on PIN proteins.

Journal: Journal of cell science 20060401

Title: Role of phospholipase D2 in the agonist-induced and constitutive endocytosis of G-protein coupled receptors.

Journal: Journal of neurochemistry 20060401

Title: Efficient sorting of TNF-alpha to rodent mast cell granules is dependent on N-linked glycosylation.

Journal: European journal of immunology 20060401

Title: Leptin biosynthetic pathway in white adipocytes.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060401

Title: The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment. Inhibitory effect of brefeldin A and monensin.

Journal: The FEBS journal 20060401

Title: Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles.

Journal: The Journal of biological chemistry 20060317

Title: The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis.

Journal: The Journal of biological chemistry 20060224

Title: Forskolin-induced cell shrinkage and apical translocation of functional enhanced green fluorescent protein-human alphaENaC in H441 lung epithelial cell monolayers.

Journal: The Journal of biological chemistry 20060224

Title: Presynaptic effectors contributing to cAMP-induced synaptic potentiation in Drosophila.

Journal: Journal of neurobiology 20060215

Title: Lipopolysaccharide prevents apoptosis induced by brefeldin A, an endoplasmic reticulum stress agent, in RAW 264.7 cells.

Journal: Biochemical and biophysical research communications 20060210

Title: Vesicular transport and apotransferrin in intestinal iron absorption, as shown in the Caco-2 cell model.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060201

Title: High density lipoprotein 3 inhibits oxidized low density lipoprotein-induced apoptosis via promoting cholesterol efflux in RAW264.7 cells.

Journal: Acta pharmacologica Sinica 20060201

Title: Expression and localization of PCSK9 in rat hepatic cells.

Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201

Title: TRPV1 antagonists elevate cell surface populations of receptor protein and exacerbate TRPV1-mediated toxicities in human lung epithelial cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060101

Title: Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL.

Journal: Blood 20060101

Title: Selective relocalization and proteasomal downregulation of PKCalpha induced by platelet-activating factor in retinal pigment epithelium.

Journal: Investigative ophthalmology & visual science 20060101

Title: Endocytosis of cell surface material mediates cell plate formation during plant cytokinesis.

Journal: Developmental cell 20060101

Title: Pulmonary surfactant transport in alveolar type II cells.

Journal: Respirology (Carlton, Vic.) 20060101

Title: Brefeldin A decreases the activity of the general amino acid permease (GAP1) and the more specific systems for L-leucine uptake in Saccharomyces cerevisiae.

Journal: Cellular & molecular biology letters 20060101

Title: Cytotoxicity of organic compounds against ovarian cancer cells: a quantitative structure-activity relationship study.

Journal: Molecular pharmaceutics 20060101

Title: Enhancement of the cytotoxicity of liposomal ricin by the carboxylic ionophore monensin and the lysosomotropic amine NH4Cl in Chinese hamster ovary cells.

Journal: International journal of toxicology 20060101

Title: [Effect of latrunculin B, jasplakinolide and brefeldin A on the store-dependent Ca2+ entry in macrophages].

Journal: Tsitologiia 20060101

Title: An aberrant sequence in a connexin46 mutant underlies congenital cataracts.

Journal: The Journal of biological chemistry 20051209

Title: Increased CXCR4-dependent HIV-1 fusion in activated T cells: role of CD4/CXCR4 association.

Journal: Journal of leukocyte biology 20051201

Title: Effects of brefeldin A on pollen germination and tube growth. Antagonistic effects on endocytosis and secretion.

Journal: Plant physiology 20051201

Title: Cytosolic Ca2+ signals depending on the functional state of the Golgi in HeLa cells.

Journal: Cell calcium 20051101

Title: A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal.

Journal: The Journal of biological chemistry 20051021

Title: Binding and functions of ADP-ribosylation factor on mammalian and yeast peroxisomes.

Journal: The Journal of biological chemistry 20051014

Title: Mechanisms of Cx43 and Cx26 transport to the plasma membrane and gap junction regeneration.

Journal: Journal of cell science 20051001

Title: Interaction between constitutively expressed heat shock protein, Hsc 70, and cysteine string protein is important for cortical granule exocytosis in Xenopus oocytes.

Journal: The Journal of biological chemistry 20050923

Title: Plasma membrane residence of hyaluronan synthase is coupled to its enzymatic activity.

Journal: The Journal of biological chemistry 20050909

Title: Accelerated discovery of novel protein function in cultured human cells.

Journal: Molecular & cellular proteomics : MCP 20050901

Title: Nuclear transfer of perchloric acid-soluble protein by endoplasmic reticulum stressors.

Journal: Protein science : a publication of the Protein Society 20050901

Title: Uncoupling of brefeldin a-mediated coatomer protein complex-I dissociation from Golgi redistribution.

Journal: Traffic (Copenhagen, Denmark) 20050901

Title: Extracellular trafficking of myocilin in human trabecular meshwork cells.

Journal: The Journal of biological chemistry 20050812

Title: Endocytosis of cholera toxin by human enterocytes is developmentally regulated.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050801

Title: Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20050801

Title: Growth factors mobilize multiple pools of KCa channels in developing parasympathetic neurons: role of ADP-ribosylation factors and related proteins.

Journal: Journal of neurophysiology 20050801

Title: On the action of Brefeldin A on Sec7-stimulated membrane-recruitment and GDP/GTP exchange of Arf proteins.

Journal: Biochemical Society transactions 20050801

Title: Coenzyme Q distribution in HL-60 human cells depends on the endomembrane system.

Journal: Biochimica et biophysica acta 20050730

Title: Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epithelium.

Journal: Biochemical and biophysical research communications 20050715

Title: Lung epithelial cells release ATP during ozone exposure: signaling for cell survival.

Journal: Free radical biology & medicine 20050715

Title: Increased specific T cell cytokine responses in patients with active pulmonary tuberculosis from Central Africa.

Journal: Microbes and infection 20050701

Title: Cellular internalization of cytolethal distending toxin: a new end to a known pathway.

Journal: Cellular microbiology 20050701

Title: AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.

Journal: Journal of neurochemistry 20050701

Title: Exosome-dependent trafficking of HSP70: a novel secretory pathway for cellular stress proteins.

Journal: The Journal of biological chemistry 20050617

Title: The Kell protein of the common K2 phenotype is a catalytically active metalloprotease, whereas the rare Kell K1 antigen is inactive. Identification of novel substrates for the Kell protein.

Journal: The Journal of biological chemistry 20050603

Title: Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.

Journal: The Journal of biological chemistry 20050603

Title: ApoA-I lipidation in primary mouse hepatocytes. Separate controls for phospholipid and cholesterol transfers.

Journal: The Journal of biological chemistry 20050603

Title: Class 1 reversibly glycosylated polypeptides are plasmodesmal-associated proteins delivered to plasmodesmata via the golgi apparatus.

Journal: The Plant cell 20050601

Title: Immunosynapse formation coincides with rapid activation of NK cells by syngeneic T cells and correlates with clustering of MHC class I.

Journal: International immunology 20050601

Title: Cx31 is assembled and trafficked to cell surface by ER-Golgi pathway and degraded by proteasomal or lysosomal pathways.

Journal: Cell research 20050601

Title: Actin-based motility of endosomes is linked to the polar tip growth of root hairs.

Journal: European journal of cell biology 20050601

Title: Mechanism of internalization of the cytolethal distending toxin of Actinobacillus actinomycetemcomitans.

Journal: Microbiology (Reading, England) 20050501

Title: Secretion of the human T cell leukemia virus type I transactivator protein tax.

Journal: The Journal of biological chemistry 20050429

Title: Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells.

Journal: Experimental cell research 20050401

Title: Endoplasmic reticulum stress-induced apoptosis is partly mediated by reduced insulin signaling through phosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase-3beta in mouse insulinoma cells.

Journal: Diabetes 20050401

Title: Ilimaquinone inhibits gap junctional communication in a connexin isotype-specific manner.

Journal: Experimental cell research 20050310

Title: Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.

Journal: Neuroscience letters 20050307

Title: Angiotensin II-induced Akt activation through the epidermal growth factor receptor in vascular smooth muscle cells is mediated by phospholipid metabolites derived by activation of phospholipase D.

Journal: The Journal of pharmacology and experimental therapeutics 20050301

Title: Cellular sublocalization of Cx43 and the establishment of functional coupling in IMR-32 neuroblastoma cells.

Journal: Molecular carcinogenesis 20050301

Title: Supernatant protein factor requires phosphorylation and interaction with Golgi to stimulate cholesterol synthesis in hepatoma cells.

Journal: Archives of biochemistry and biophysics 20050301

Title: Ca2+ permeability of the plasma membrane induced by rotavirus infection in cultured cells is inhibited by tunicamycin and brefeldin A.

Journal: Virology 20050301

Title: Filamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression.

Journal: The Journal of biological chemistry 20050225

Title: Endoproteolytic cleavage of human thyroperoxidase: role of the propeptide in the protein folding process.

Journal: The Journal of biological chemistry 20050211

Title: Requirement of the vesicular system for membrane permeabilization by Sindbis virus.

Journal: Virology 20050205

Title: Dissection of brefeldin A-sensitive and -insensitive steps in apicoplast protein targeting.

Journal: Journal of cell science 20050201

Title: Intracellular localization and trafficking of fluorescein-labeled cisplatin in human ovarian carcinoma cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050115

Title: Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. Role in cell survival.

Journal: The Journal of biological chemistry 20050114

Title: cAMP acts on exchange protein activated by cAMP/cAMP-regulated guanine nucleotide exchange protein to regulate transmitter release at the crayfish neuromuscular junction.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050105

Title: Release of ATP from retinal pigment epithelial cells involves both CFTR and vesicular transport.

Journal: American journal of physiology. Cell physiology 20050101

Title: Structure and dynamics of the Golgi complex at 15 degrees C: low temperature induces the formation of Golgi-derived tubules.

Journal: Traffic (Copenhagen, Denmark) 20050101

Title: Secretion of ATP from Schwann cells in response to uridine triphosphate.

Journal: The European journal of neuroscience 20050101

Title: Reevaluation of the 22-1-1 antibody and its putative antigen, EBAG9/RCAS1, as a tumor marker.

Journal: BMC cancer 20050101

Title: Connexin-made channels as pharmacological targets.

Journal: Current pharmaceutical design 20050101

Title: CD4 and CD8 T cell response to the rHSP60 from Klebsiella pneumoniae in peripheral blood mononuclear cells from patients with ankylosing spondylitis.

Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101

Title: Interaction of Arl1 GTPase with the GRIP domain of Golgin-245 as assessed by GST (glutathione-S-transferase) pull-down experiments.

Journal: Methods in enzymology 20050101

Title: Palmitoylation of inducible nitric-oxide synthase at Cys-3 is required for proper intracellular traffic and nitric oxide synthesis.

Journal: The Journal of biological chemistry 20041231

Title: Bordetella pertussis adenylate cyclase delivers chemically coupled CD8+ T-cell epitopes to dendritic cells and elicits CTL in vivo.

Journal: Vaccine 20041216

Title: Stabilin-1 localizes to endosomes and the trans-Golgi network in human macrophages and interacts with GGA adaptors.

Journal: Journal of leukocyte biology 20041201

Title: MHC class I-associated presentation of exogenous peptides is not only enhanced but also prolonged by linking with a C-terminal Lys-Asp-Glu-Leu endoplasmic reticulum retrieval signal.

Journal: European journal of immunology 20041201

Title: In vitro culture of Arabidopsis embryos within their ovules.

Journal: The Plant journal : for cell and molecular biology 20041201

Title: In vivo recruitment by painful stimuli of AMPA receptor subunits to the plasma membrane of spinal cord neurons.

Journal: Pain 20041201

Title: Modulation of cerebral vascular tone by activated glia: involvement of nitric oxide.

Journal: Journal of neurochemistry 20041201

Title: Ganglioside GD3 traffics from the trans-Golgi network to plasma membrane by a Rab11-independent and brefeldin A-insensitive exocytic pathway.

Journal: The Journal of biological chemistry 20041112

Title: Hsp70 release from peripheral blood mononuclear cells.

Journal: Biochemical and biophysical research communications 20041112

Title: Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase.

Journal: The Journal of biological chemistry 20041105

Title: Double cross-over gene replacement within the sec 7 domain of a GDP-GTP exchange factor from Plasmodium falciparum allows the generation of a transgenic brefeldin A-resistant parasite line.

Journal: Molecular and biochemical parasitology 20041101

Title: The kinase activity of fibroblast growth factor receptor 3 with activation loop mutations affects receptor trafficking and signaling.

Journal: The Journal of biological chemistry 20041008

Title: ADP-ribosylation factor6 regulates both [3H]-noradrenaline and [14C]-glutamate exocytosis through phosphatidylinositol 4,5-bisphosphate.

Journal: Neurochemistry international 20041001

Title: Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.

Journal: Circulation research 20041001

Title: Cathepsin D released by lactating rat mammary epithelial cells is involved in prolactin cleavage under physiological conditions.

Journal: Journal of cell science 20041001

Title: Comparison between the effects of fusicoccin, Tunicamycin, and Brefeldin A on programmed cell death of cultured sycamore (Acer pseudoplatanus L.) cells.

Journal: Protoplasma 20041001

Title: Regulation of the cell surface expression and function of angiotensin II type 1 receptor by Rab1-mediated endoplasmic reticulum-to-Golgi transport in cardiac myocytes.

Journal: The Journal of biological chemistry 20040924

Title: ADRP is dissociated from lipid droplets by ARF1-dependent mechanism.

Journal: Biochemical and biophysical research communications 20040924

Title: Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901

Title: Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines.

Journal: Journal of neurochemistry 20040901

Title: VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx.

Journal: Molecular cell 20040827

Title: Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.

Journal: FEBS letters 20040827

Title: Mu-opioid receptor trafficking on inhibitory synapses in the rat brainstem.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040818

Title: Association of major histocompatibility complex II with cholesterol- and sphingolipid-rich membranes precedes peptide loading.

Journal: The Journal of biological chemistry 20040813

Title: Identification of prodomain determinants involved in ADAMTS-1 biosynthesis.

Journal: The Journal of biological chemistry 20040806

Title: Brefeldin A and filipin distinguish two globotriaosyl ceramide/verotoxin-1 intracellular trafficking pathways involved in Vero cell cytotoxicity.

Journal: Glycobiology 20040801

Title: The recycling of apolipoprotein E and its amino-terminal 22 kDa fragment: evidence for multiple redundant pathways.

Journal: Journal of lipid research 20040801

Title: Dynamic nucleation of Golgi apparatus assembly from the endoplasmic reticulum in interphase hela cells.

Journal: Traffic (Copenhagen, Denmark) 20040801

Title: Transactivation of Trk neurotrophin receptors by G-protein-coupled receptor ligands occurs on intracellular membranes.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040728

Title: The ORF3 protein of hepatitis E virus interacts with liver-specific alpha1-microglobulin and its precursor alpha1-microglobulin/bikunin precursor (AMBP) and expedites their export from the hepatocyte.

Journal: The Journal of biological chemistry 20040709

Title: Stem domains of heparan sulfate 6-O-sulfotransferase are required for Golgi localization, oligomer formation and enzyme activity.

Journal: Journal of cell science 20040701

Title: Effects of protein transport inhibitors on the distribution and secretion of the fusion protein RntA-EGFP in Aspergillus oryzae.

Journal: Bioscience, biotechnology, and biochemistry 20040701

Title: Endoplasmic reticulum resident, immunoglobulin joining chain, can be secreted by perturbation of the calcium concentration in the endoplasmic reticulum.

Journal: DNA and cell biology 20040701

Title: Dicumarol, an inhibitor of ADP-ribosylation of CtBP3/BARS, fragments golgi non-compact tubular zones and inhibits intra-golgi transport.

Journal: European journal of cell biology 20040701

Title: AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells.

Journal: The Journal of biological chemistry 20040611

Title: Intracellular trafficking and degradation of unassociated proalpha2 chains of collagen type I.

Journal: Experimental cell research 20040610

Title: Human pancreatic duct cells can produce tumour necrosis factor-alpha that damages neighbouring beta cells and activates dendritic cells.

Journal: Diabetologia 20040601

Title: Hyperactivity of endoplasmic reticulum associated exocytosis mechanism contributes to acute phencyclidine intoxication.

Journal: Journal of pharmacological sciences 20040601

Title: Enantioselective total synthesis of (+)-brefeldin A and 7-epi-brefeldin A.

Journal: The Journal of organic chemistry 20040528

Title: The establishment of telomerase-immortalized Tangier disease cell lines indicates the existence of an apolipoprotein A-I-inducible but ABCA1-independent cholesterol efflux pathway.

Journal: The Journal of biological chemistry 20040514

Title: A 'chiral aldehyde' equivalent as a building block towards biologically active targets.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040503

Title: Important role for the V-type H(+)-ATPase and the Golgi apparatus in the recycling of PTH/PTHrP receptor.

Journal: American journal of physiology. Endocrinology and metabolism 20040501

Title: Analyzing T-cell responses to cytomegalovirus by cytokine flow cytometry.

Journal: Human immunology 20040501

Title: Analysis of antigen-specific T-cell responses with synthetic peptides--what kind of peptide for which purpose?

Journal: Human immunology 20040501

Title: Fluorescent analogues of plasma membrane sphingolipids are sorted to different intracellular compartments in astrocytes; Harmful effects of chronic ethanol exposure on sphingolipid trafficking and metabolism.

Journal: FEBS letters 20040409

Title: Atrophic macular degeneration mutations in ELOVL4 result in the intracellular misrouting of the protein.

Journal: Genomics 20040401

Title: Involvement of ERK MAP kinase in endoplasmic reticulum stress in SH-SY5Y human neuroblastoma cells.

Journal: Journal of neurochemistry 20040401

Title: Alternative processing for MHC class I presentation by immature and CpG-activated dendritic cells.

Journal: European journal of immunology 20040401

Title: [Activation of G-proteins in three dimensions: one step toward the therapeutic inhibition of nucleotide exchange factors].

Journal: Medecine sciences : M/S 20040401

Title: A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides.

Journal: The Journal of biological chemistry 20040326

Title: Dynamic and intracellular trafficking of P-glycoprotein-EGFP fusion protein: Implications in multidrug resistance in cancer.

Journal: International journal of cancer 20040320

Title: Induction of cytokines by toxins that have an identical RNA N-glycosidase activity: Shiga toxin, ricin, and modeccin.

Journal: Biochimica et biophysica acta 20040317

Title: Developmental-stage-specific triacylglycerol biosynthesis, degradation and trafficking as lipid bodies in Plasmodium falciparum-infected erythrocytes.

Journal: Journal of cell science 20040315

Title: Depletion of pre-beta-high density lipoprotein by human chymase impairs ATP-binding cassette transporter A1- but not scavenger receptor class B type I-mediated lipid efflux to high density lipoprotein.

Journal: The Journal of biological chemistry 20040312

Title: Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle.

Journal: Experimental cell research 20040310

Title: Identification of multivesicular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells.

Journal: The Plant cell 20040301

Title: The tumor suppressor activity of MDA-7/IL-24 is mediated by intracellular protein expression in NSCLC cells.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20040301

Title: Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.

Journal: The Journal of biological chemistry 20040213

Title: Recycling, degradation and sensitivity to the synergistic anion of transferrin in the receptor-independent route of iron uptake by human hepatoma (HuH-7) cells.

Journal: The international journal of biochemistry & cell biology 20040201

Title: Identification of the protein storage vacuole and protein targeting to the vacuole in leaf cells of three plant species.

Journal: Plant physiology 20040201

Title: The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609.

Journal: Journal of lipid research 20040101

Title: Aggregation and loss of cytokeratin filament networks inhibit golgi organization in liver-derived epithelial cell lines.

Journal: Cell motility and the cytoskeleton 20040101

Title: A novel gene mutation in the 60s loop of human coagulation factor VII - inhibition of interdomain crosstalk.

Journal: Thrombosis and haemostasis 20040101

Title: Microtubule-dependent redistribution of a cytoplasmic cornified envelope precursor.

Journal: The Journal of investigative dermatology 20040101

Title: LAK cells kill Fas- cancer cells using the Tag7/Hsp70 protein complex secreted from the Golgi apparatus.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20040101

Title: Functional lymphocyte subset assessment of the Th1/Th2 profile in patients with autoimmune thyroiditis by flowcytometric analysis of peripheral lymphocytes.

Journal: Journal of biological regulators and homeostatic agents 20040101

Title: Glucose transport in lactation.

Journal: Advances in experimental medicine and biology 20040101

Title: Bidirectional regulation of renal cortical Na+,K+-ATPase by protein kinase C.

Journal: Acta biochimica Polonica 20040101

Title: cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.

Journal: The Journal of biological chemistry 20031226

Title: Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor.

Journal: Nature 20031204

Title: Activation of the store-operated calcium current ICRAC can be dissociated from regulated exocytosis in rat basophilic leukaemia (RBL-1) cells.

Journal: The Journal of physiology 20031201

Title: Constitutive secretion of MMP9 by early-passage cultured human endothelial cells.

Journal: Cell biochemistry and function 20031201

Title: BFA-sensitive and insensitive exocytic pathways in Entamoeba histolytica trophozoites: their relationship to pathogenesis.

Journal: Cellular microbiology 20031201

Title: Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism.

Journal: Molecular cell 20031201

Title: The paranodal complex of F3/contactin and caspr/paranodin traffics to the cell surface via a non-conventional pathway.

Journal: The Journal of biological chemistry 20031128

Title: Release of canine parvovirus from endocytic vesicles.

Journal: Virology 20031125

Title: The effects of drugs inhibiting protein secretion in the filamentous fungus Trichoderma reesei. Evidence for down-regulation of genes that encode secreted proteins in the stressed cells.

Journal: The Journal of biological chemistry 20031107

Title: Accumulation of Hsp70/Hsc70 molecular chaperone regulator BAG-1 on COPI-coated structures in gastric epithelial cells.

Journal: International journal of oncology 20031101

Title: Characterization of the in vitro retrograde transport of MPR46.

Journal: Traffic (Copenhagen, Denmark) 20031101

Title: The conversion of apoB100 low density lipoprotein/high density lipoprotein particles to apoB100 very low density lipoproteins in response to oleic acid occurs in the endoplasmic reticulum and not in the Golgi in McA RH7777 cells.

Journal: The Journal of biological chemistry 20031024

Title: Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.

Journal: The Journal of biological chemistry 20031017

Title: The amyloid precursor protein protects PC12 cells against endoplasmic reticulum stress-induced apoptosis.

Journal: Journal of neurochemistry 20031001

Title: Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions.

Journal: Cell death and differentiation 20031001

Title: Establishment of gemcitabine-resistant human pancreatic cancer cells and effect of brefeldin-a on the resistant cell line.

Journal: Pancreas 20031001

Title: pH-dependent translocation of alpha-tocopherol transfer protein (alpha-TTP) between hepatic cytosol and late endosomes.

Journal: Genes to cells : devoted to molecular & cellular mechanisms 20031001

Title: Role of ADP-ribosylation factor 6 (ARF6) in gastric acid secretion.

Journal: The Journal of biological chemistry 20030919

Title: Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP).

Journal: The Journal of biological chemistry 20030912

Title: ADP-ribosylation factor-dependent phospholipase D activation by the M3 muscarinic receptor.

Journal: The Journal of biological chemistry 20030905

Title: Class A scavenger receptor-mediated adhesion and internalization require distinct cytoplasmic domains.

Journal: The Journal of biological chemistry 20030905

Title: Thyroid hormone stimulates Na-K-ATPase activity and its plasma membrane insertion in rat alveolar epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20030901

Title: Effect of maternal obstructive cholestasis during pregnancy on the biliary transport of horseradish peroxidase in the rat offspring.

Journal: Clinical science (London, England : 1979) 20030901

Title: N-glycosylation is required for the surface localization of MUC17 mucin.

Journal: International journal of oncology 20030901

Title: In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20030901

Title: Mimotopes of tumor-associated T-cell epitopes for cancer vaccines determined with combinatorial peptide libraries.

Journal: Molecular biotechnology 20030901

Title: Biochemical determination of natural tumor-associated T-cell epitopes.

Journal: Molecular biotechnology 20030901

Title: Selective lack of the C16:0 fatty acid isoform of sulfatide in pancreas of type II diabetic animal models.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20030901

Title: Intracellular cleavage of human influenza a virus hemagglutinin and its inhibition.

Journal: Biochemistry. Biokhimiia 20030901

Title: Arabidopsis sterol endocytosis involves actin-mediated trafficking via ARA6-positive early endosomes.

Journal: Current biology : CB 20030819

Title: Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells.

Journal: The Journal of biological chemistry 20030808

Title: Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis.

Journal: Cell death and differentiation 20030801

Title: Transcytosis of GCSF-transferrin across rat alveolar epithelial cell monolayers.

Journal: Pharmaceutical research 20030801

Title: Overexpression and mislocalization of a tail-anchored GFP redefines the identity of peroxisomal ER.

Journal: Traffic (Copenhagen, Denmark) 20030701

Title: Dendritic cell maturation enhances CD8+ T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading.

Journal: Immunology 20030701

Title: Coupling endoplasmic reticulum stress to cell death program in isolated human pancreatic islets: effects of gene transfer of Bcl-2.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20030701

Title: The cytopathic 18f strain of Hepatitis A virus induces RNA degradation in FrhK4 cells.

Journal: Archives of virology 20030701

Title: Histamine antagonizes tumor necrosis factor (TNF) signaling by stimulating TNF receptor shedding from the cell surface and Golgi storage pool.

Journal: The Journal of biological chemistry 20030613

Title: Epidermal growth factor and insulin short-term increase hPepT1-mediated glycylsarcosine uptake in Caco-2 cells.

Journal: Acta physiologica Scandinavica 20030601

Title: Modulation of constitutive and delayed apoptosis by brefeldin A in human neutrophils.

Journal: International immunopharmacology 20030601

Title: Immunoglobulin light chains dictate vesicular transport-dependent and -independent routes for IgM degradation by the ubiquitin-proteasome pathway.

Journal: The Journal of biological chemistry 20030523

Title: Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network.

Journal: The Journal of biological chemistry 20030516

Title: The GTPase ARF1p controls the sequence-specific vacuolar sorting route to the lytic vacuole.

Journal: The Plant cell 20030501

Title: Transcription factor expression and cellular redox in immature oligodendrocyte cell death: effect of Bcl-2.

Journal: Molecular and cellular neurosciences 20030401

Title: C-terminal extension of phaseolin with a short methionine-rich sequence can inhibit trimerisation and result in high instability.

Journal: Plant molecular biology 20030401

Title: Secretory vesicular transport from the Golgi is altered during ATP-binding cassette protein A1 (ABCA1)-mediated cholesterol efflux.

Journal: The Journal of biological chemistry 20030321

Title: Ceramide in nitric oxide inhibition of glioma cell growth. Evidence for the involvement of ceramide traffic.

Journal: The Journal of biological chemistry 20030314

Title: Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.

Journal: European journal of immunology 20030301

Title: Thiol oxidation by 2,2'-dithiodipyridine induced calcium mobilization in MG63 human osteosarcoma cells.

Journal: Life sciences 20030227

Title: Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in HT 1080 fibrosarcoma cells.

Journal: FEBS letters 20030227

Title: A 14-amino acid sequence with a beta-turn structure is required for apical membrane sorting of the rat ileal bile acid transporter.

Journal: The Journal of biological chemistry 20030207

Title: Metabotropic glutamate receptors activate phospholipase D in astrocytes through a protein kinase C-dependent and Rho-independent pathway.

Journal: Neuropharmacology 20030201

Title: Identification of genes in thyrocytes regulated by unfolded protein response by using disulfide bond reducing agent of dithiothreitol.

Journal: Journal of endocrinological investigation 20030201

Title: The Cu,Zn superoxide dismutase in neuroblastoma SK-N-BE cells is exported by a microvesicles dependent pathway.

Journal: Brain research. Molecular brain research 20030131

Title: Do phytotropins inhibit auxin efflux by impairing vesicle traffic?

Journal: Plant physiology 20030101

Title: Constitutive secretion of the granule chymase mouse mast cell protease-1 and the chemokine, CCL2, by mucosal mast cell homologues.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030101

Title: Suppression of tumor necrosis factor-alpha by beta2-adrenoceptor activation: role of mitogen-activated protein kinases in renal mesangial cells.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030101

Title: Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion.

Journal: Bioscience, biotechnology, and biochemistry 20030101

Title: Regulation of renal Na(+),K(+)-ATPase and ouabain-sensitive H(+),K(+)-ATPase by the cyclic AMP-protein kinase A signal transduction pathway.

Journal: Acta biochimica Polonica 20030101

Title: Insights into mechanisms responsible for mesangial alterations associated with fibrogenic glomerulopathic light chains.

Journal: Nephron. Physiology 20030101

Title: Osteopontin traffic in hypoxic renal epithelial cells.

Journal: Nephron. Experimental nephrology 20030101

Title: Characterization of rat parotid and submandibular acinar cell apoptosis in primary culture.

Journal: In vitro cellular & developmental biology. Animal 20030101

Title: Sub-cellular trafficking of phytochemicals explored using auto-fluorescent compounds in maize cells.

Journal: BMC plant biology 20030101

Title: BAD and Bcl-2 regulation are early events linking neuronal endoplasmic reticulum stress to mitochondria-mediated apoptosis.

Journal: Brain research. Molecular brain research 20021230

Title: Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation.

Journal: The Journal of biological chemistry 20021213

Title: Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells.

Journal: The Journal of biological chemistry 20021206

Title: Arf1 dissociates from the clathrin adaptor GGA prior to being inactivated by Arf GTPase-activating proteins.

Journal: The Journal of biological chemistry 20021206

Title: Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress.

Journal: Journal of neurochemistry 20021201

Title: Structural integrity of the Golgi stack is essential for normal secretory functions of rat parotid acinar cells: effects of brefeldin A and okadaic acid.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20021201

Title: Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation.

Journal: The Journal of biological chemistry 20021122

Title: Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes.

Journal: The Journal of biological chemistry 20021115

Title: Epstein-barr virus latent membrane protein 1 induces and causes release of fibroblast growth factor-2.

Journal: Cancer research 20021101

Title: The mechanism of docosahexaenoic acid-induced phospholipase D activation in human lymphocytes involves exclusion of the enzyme from lipid rafts.

Journal: The Journal of biological chemistry 20021018

Title: Buds of the Golgi apparatus in parotid acinar cells.

Journal: European journal of morphology 20021001

Title: Effect of nordihydroguaiaretic acid on the secretion of lipoprotein lipase.

Journal: Journal of biochemistry and molecular biology 20020930

Title: Sulfation in the Golgi lumen of Madin-Darby canine kidney cells is inhibited by brefeldin A and depends on a factor present in the cytoplasm and on Golgi membranes.

Journal: The Journal of biological chemistry 20020927

Title: Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors.

Journal: The Journal of biological chemistry 20020906

Title: Vesicle transmembrane potential is required for translocation to the cytosol of externally added FGF-1.

Journal: The EMBO journal 20020902

Title: Cycling of early Golgi proteins via the cell surface and endosomes upon lumenal pH disruption.

Journal: Traffic (Copenhagen, Denmark) 20020901

Title: Resistance against ricin-induced apoptosis in a brefeldin A-resistant mutant cell line (BER-40) of Vero cells.

Journal: Journal of biochemistry 20020901

Title: F-actin-dependent endocytosis of cell wall pectins in meristematic root cells. Insights from brefeldin A-induced compartments.

Journal: Plant physiology 20020901

Title: Trophoblast origin of hCG isoforms: cytotrophoblasts are the primary source of choriocarcinoma-like hCG.

Journal: Molecular and cellular endocrinology 20020830

Title: Chemokine receptor CCR5: polymorphism at protein level.

Journal: Biochemical and biophysical research communications 20020816

Title: Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.

Journal: Journal of neuroscience research 20020815

Title: 4-Aryloxybutenolides as 'chiral aldehyde' equivalents: an efficient enantioselective synthesis of (+)-brefeldin a.

Journal: Journal of the American Chemical Society 20020814

Title: Response of VEGF expression to amino acid deprivation and inducers of endoplasmic reticulum stress.

Journal: Investigative ophthalmology & visual science 20020801

Title: Molecular cloning and characterization of a secretory neutral ceramidase of Drosophila melanogaster.

Journal: Journal of biochemistry 20020801

Title: Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020801

Title: Dexamethasone induces the secretion of annexin I in immature lymphoblastic cells by a calcium-dependent mechanism.

Journal: Molecular and cellular biochemistry 20020801

Title: The stack of the golgi apparatus.

Journal: Archives of histology and cytology 20020801

Title: The minor regulated pathway, a rapid component of salivary secretion, may provide docking/fusion sites for granule exocytosis at the apical surface of acinar cells.

Journal: Journal of cell science 20020715

Title: GBF1, a guanine nucleotide exchange factor for ADP-ribosylation factors, is localized to the cis-Golgi and involved in membrane association of the COPI coat.

Journal: Traffic (Copenhagen, Denmark) 20020701

Title: FXYD7 is a brain-specific regulator of Na,K-ATPase alpha 1-beta isozymes.

Journal: The EMBO journal 20020701

Title: Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts.

Journal: Toxicology and applied pharmacology 20020701

Title: Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway.

Journal: The Journal of biological chemistry 20020614

Title: Longitudinal study of intracellular T cell cytokine production in infants compared to adults.

Journal: Clinical and experimental immunology 20020601

Title: The cytoskeleton and the secretory pathway are not involved in targeting the cowpea mosaic virus movement protein to the cell periphery.

Journal: Virology 20020525

Title: Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.

Journal: The Journal of biological chemistry 20020517

Title: Effect of clomiphene on Ca(2+) movement in human prostate cancer cells.

Journal: Life sciences 20020517

Title: Furin proteolytically processes the heparin-binding region of extracellular superoxide dismutase.

Journal: The Journal of biological chemistry 20020510

Title: Calcium influx factor from cytochrome P-450 metabolism and secretion-like coupling mechanisms for capacitative calcium entry in corneal endothelial cells.

Journal: The Journal of biological chemistry 20020510

Title: Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras.

Journal: The Journal of biological chemistry 20020510

Title: Dissection of COPI and Arf1 dynamics in vivo and role in Golgi membrane transport.

Journal: Nature 20020509

Title: Effects of brefeldin A and nordihydroguaiaretic acid on endomembrane dynamics and lipid synthesis in plant cells.

Journal: FEBS letters 20020508

Title: Fragmentation and dispersal of the pericentriolar Golgi complex is required for entry into mitosis in mammalian cells.

Journal: Cell 20020503

Title: Golgi apparatus dynamics during mouse oocyte in vitro maturation: effect of the membrane trafficking inhibitor brefeldin A.

Journal: Biology of reproduction 20020501

Title: IL-16 promotes leukotriene C(4) and IL-4 release from human eosinophils via CD4- and autocrine CCR3-chemokine-mediated signaling.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020501

Title: Release of intact, monomeric cytochrome c from apoptotic and necrotic cells.

Journal: Cell death and differentiation 20020501

Title: Involvement of glycogen synthase kinase-3beta and tau phosphorylation in neuronal Golgi disassembly.

Journal: Journal of neurochemistry 20020501

Title: Release of an acid phosphatase activity during lily pollen tube growth involves components of the secretory pathway.

Journal: Protoplasma 20020501

Title: A role for small GTPase RhoA in regulating intracellular membrane traffic of lysosomes in invasive rat hepatoma cells.

Journal: The Histochemical journal 20020501

Title: Ligands act as pharmacological chaperones and increase the efficiency of delta opioid receptor maturation.

Journal: The EMBO journal 20020402

Title: T lymphocyte expression of thrombospondin-1 and adhesion to extracellular matrix components.

Journal: European journal of immunology 20020401

Title: Contribution of phopholipase D and a brefeldin A-sensitive ARF to chemoattractant-induced superoxide production and secretion of human neutrophils.

Journal: Journal of leukocyte biology 20020401

Title: The fate of newly synthesized V-ATPase accessory subunit Ac45 in the secretory pathway.

Journal: European journal of biochemistry 20020401

Title: Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization.

Journal: Cell death and differentiation 20020401

Title: Secretion of egg envelope protein ZPC after C-terminal proteolytic processing in quail granulosa cells.

Journal: European journal of biochemistry 20020401

Title: rab4 regulates transport to the apical plasma membrane in Madin-Darby canine kidney cells.

Journal: The Journal of biological chemistry 20020322

Title: Mechanism of domain closure of Sec7 domains and role in BFA sensitivity.

Journal: Biochemistry 20020319

Title: Effect of brefeldin A on heparan sulphate biosynthesis in Madin-Darby canine kidney cells.

Journal: The Biochemical journal 20020301

Title: Possible implication of Golgi-nucleating function for the centrosome.

Journal: Biochemical and biophysical research communications 20020301

Title: Redistribution of membrane proteins between the Golgi apparatus and endoplasmic reticulum in plants is reversible and not dependent on cytoskeletal networks.

Journal: The Plant journal : for cell and molecular biology 20020301

Title: Differential modulation of surface and intracellular protein expression by T cells after stimulation in the presence of monensin or brefeldin A.

Journal: Clinical and diagnostic laboratory immunology 20020301

Title: Cellular processing of a multibranched lysine core with tumor antigen peptides and presentation of peptide epitopes recognized by cytotoxic T lymphocytes on antigen-presenting cells.

Journal: Cancer research 20020301

Title: Regulators of GTP-binding proteins cause morphological changes in the vacuole system of the filamentous fungus, Pisolithus tinctorius.

Journal: Cell motility and the cytoskeleton 20020301

Title: The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity.

Journal: Journal of neurochemistry 20020301

Title: Cell polarity signaling in Arabidopsis involves a BFA-sensitive auxin influx pathway.

Journal: Current biology : CB 20020219

Title: Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20020215

Title: ATP is released from guinea pig ureter epithelium on distension.

Journal: American journal of physiology. Renal physiology 20020201

Title: Retention at the cis-Golgi and delayed degradation of tissue-non-specific alkaline phosphatase with an Asn153-->Asp substitution, a cause of perinatal hypophosphatasia.

Journal: The Biochemical journal 20020201

Title: Effect of 17beta-estradiol on intracellular Ca(2+) levels in renal tubular cells.

Journal: Pharmacology 20020201

Title: Characterization of Herpesvirus saimiri-transformed T lymphocytes from common variable immunodeficiency patients.

Journal: Clinical and experimental immunology 20020201

Title: The calcium-binding protein p54/NEFA is a novel luminal resident of medial Golgi cisternae that traffics independently of mannosidase II.

Journal: European journal of cell biology 20020201

Title: Cell surface trafficking of Fas in NIT-1 cells and dissection of surface and total Fas expression.

Journal: Biochemical and biophysical research communications 20020111

Title: Differential effect of brefeldin A on the palmitoylation of surfactant protein C proprotein mutants.

Journal: Biochemical and biophysical research communications 20020111

Title: BIG1 and BIG2: brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors.

Journal: Methods in enzymology 20020101

Title: Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells.

Journal: Cellular signalling 20020101

Title: Organization of cyclic AMP-dependent connexin 43 in Swiss 3T3 cells attached to a cellulose substratum.

Journal: Biomaterials 20020101

Title: Recycling ability of the mouse and the human neurotensin type 2 receptors depends on a single tyrosine residue.

Journal: Journal of cell science 20020101

Title: Uptake of a fluorescent marker in plant cells is sensitive to brefeldin A and wortmannin.

Journal: The Plant cell 20020101

Title: ARF-directed guanine-nucleotide-exchange (GEP) proteins.

Journal: Methods in molecular biology (Clifton, N.J.) 20020101

Title: A novel caspase dependent pathway is involved in apoptosis of human endothelial cells by Shiga toxins.

Journal: Microbiology and immunology 20020101

Title: An extracellular monoADP-ribosyl transferase activity in Entamoeba histolytica trophozoites.

Journal: The Journal of eukaryotic microbiology 20020101

Title: Correction of cross-linker sensitivity of Fanconi anemia group F cells by CD33-mediated protein transfer.

Journal: Blood 20011215

Title: Half-lives of plasma membrane Na(+)/H(+) exchangers NHE1-3: plasma membrane NHE2 has a rapid rate of degradation.

Journal: American journal of physiology. Cell physiology 20011201

Title: Localization of p24 putative cargo receptors in the early secretory pathway depends on the biosynthetic activity of the cell.

Journal: The Biochemical journal 20011201

Title: D-glucose releases 5-hydroxytryptamine from human BON cells as a model of enterochromaffin cells.

Journal: Gastroenterology 20011201

Title: Distribution, transport, and degradation of apolipoprotein B-100 in HepG2 cells.

Journal: Journal of lipid research 20011201

Title: Identification and characterization of two novel mutations (Q421 K and R123P) in congenital factor XII deficiency.

Journal: Thrombosis and haemostasis 20011201

Title: A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii.

Journal: The Journal of biological chemistry 20011130

Title: Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome.

Journal: Experimental cell research 20011115

Title: Functional and physical interactions of the adaptor protein complex AP-4 with ADP-ribosylation factors (ARFs).

Journal: The EMBO journal 20011115

Title: PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine.

Journal: The Journal of clinical investigation 20011115

Title: Preparation and evaluation of sulfide derivatives of the antibiotic brefeldin a as potential prodrug candidates with enhanced aqueous solubilities.

Journal: Journal of medicinal chemistry 20011108

Title: Multiple pathways in the trafficking and assembly of connexin 26, 32 and 43 into gap junction intercellular communication channels.

Journal: Journal of cell science 20011101

Title: FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments.

Journal: Journal of cell science 20011101

Title: Multimeric connexin interactions prior to the trans-Golgi network.

Journal: Journal of cell science 20011101

Title: The role of phosphoinositide 3-kinase in the sorting and transport of newly synthesized tyrosinase-related protein-1 (TRP-1).

Journal: The journal of investigative dermatology. Symposium proceedings 20011101

Title: Prion protein protects human neurons against Bax-mediated apoptosis.

Journal: The Journal of biological chemistry 20011019

Title: Long-lasting aberrant tubulovesicular membrane inclusions accumulate in developing motoneurons after a sublethal excitotoxic insult: a possible model for neuronal pathology in neurodegenerative disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011015

Title: In vitro processing and presentation of a lipidated cytotoxic T-cell epitope derived from measles virus fusion protein.

Journal: Vaccine 20011012

Title: Kif1C, a kinesin-like motor protein, mediates mouse macrophage resistance to anthrax lethal factor.

Journal: Current biology : CB 20011002

Title: Gap junction assembly: PTX-sensitive G proteins regulate the distribution of connexin43 within cells.

Journal: American journal of physiology. Cell physiology 20011001

Title: Enhanced GM3 expression, associated with decreased invasiveness, is induced by brefeldin A in bladder cancer cells.

Journal: International journal of oncology 20011001

Title: Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein.

Journal: The EMBO journal 20011001

Title: N-linked glycosylation of macrophage-derived PAF-AH is a major determinant of enzyme association with plasma HDL.

Journal: Journal of lipid research 20011001

Title: Insulin inhibits the maturation phase of VLDL assembly via a phosphoinositide 3-kinase-mediated event.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20011001

Title: Enhancement of diphtheria toxin-induced apoptosis in Vero cells by combination treatment with brefeldin A and okadaic acid.

Journal: Cell structure and function 20011001

Title: Auxin transport inhibitors block PIN1 cycling and vesicle trafficking.

Journal: Nature 20010927

Title: Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation.

Journal: The Journal of biological chemistry 20010921

Title: A verotoxin 1 B subunit-lambda CRO chimeric protein specifically binds both DNA and globotriaosylceramide (Gb(3)) to effect nuclear targeting of exogenous DNA in Gb(3) positive cells.

Journal: Experimental cell research 20010910

Title: Activation of the luteinizing hormone/choriogonadotropin hormone receptor promotes ADP ribosylation factor 6 activation in porcine ovarian follicular membranes.

Journal: The Journal of biological chemistry 20010907

Title: Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation.

Journal: The Journal of biological chemistry 20010907

Title: Reversal of physiological stress-induced resistance to topoisomerase II inhibitors using an inducible phosphorylation site-deficient mutant of I kappa B alpha.

Journal: Molecular pharmacology 20010901

Title: Dynamic and stable pools of apoE differ functionally at the HepG2 cell surface.

Journal: Journal of lipid research 20010901

Title: Inhibitory effects of brefeldin A, a membrane transport blocker, on the bradykinin-induced hyperpolarization-mediated relaxation in the porcine coronary artery.

Journal: British journal of pharmacology 20010901

Title: Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.

Journal: Clinical and experimental immunology 20010901

Title: Cholesterol depletion by methyl-beta-cyclodextrin blocks cholera toxin transport from endosomes to the Golgi apparatus in hippocampal neurons.

Journal: Journal of neurochemistry 20010901

Title: A point mutation in an unusual Sec7 domain is linked to brefeldin A resistance in a Plasmodium falciparum line generated by drug selection.

Journal: Molecular microbiology 20010901

Title: Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation.

Journal: Biochimica et biophysica acta 20010815

Title: Steady-state localization of a medial-Golgi glycosyltransferase involves transit through the trans-Golgi network.

Journal: The Biochemical journal 20010815

Title: PKCdelta is required for mitochondrial-dependent apoptosis in salivary epithelial cells.

Journal: The Journal of biological chemistry 20010810

Title: Nerve growth factor activates persistent Rap1 signaling in endosomes.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010801

Title: The juxtamembrane lysine and arginine residues of surfactant protein C precursor influence palmitoylation via effects on trafficking.

Journal: American journal of respiratory cell and molecular biology 20010801

Title: Characterization of clofibrate-induced retrograde Golgi membrane movement to the endoplasmic reticulum: clofibrate distinguishes the Golgi from the trans Golgi network.

Journal: Bioscience, biotechnology, and biochemistry 20010801

Title: FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis.

Journal: Journal of cell science 20010801

Title: Matrix vesicles and media vesicles as nonclassical pathways for the secretion of m-Calpain from MC3T3-E1 cells.

Journal: Biochemical and biophysical research communications 20010720

Title: Transmembrane domain length determines intracellular membrane compartment localization of syntaxins 3, 4, and 5.

Journal: American journal of physiology. Cell physiology 20010701

Title: Membrane trafficking machinery components associated with the mammalian acrosome during spermiogenesis.

Journal: Experimental cell research 20010701

Title: TIP47 is not a component of lipid droplets.

Journal: The Journal of biological chemistry 20010629

Title: Brefeldin A block of integrin-dependent mechanosensitive ATP release from Xenopus oocytes reveals a novel mechanism of mechanotransduction.

Journal: The Journal of biological chemistry 20010629

Title: Involvement of ADP-ribosylation factor 1 in cholera toxin-induced morphological changes of Chinese hamster ovary cells.

Journal: The Journal of biological chemistry 20010622

Title: Resting (basal) secretion of proteins is provided by the minor regulated and constitutive-like pathways and not granule exocytosis in parotid acinar cells.

Journal: The Journal of biological chemistry 20010622

Title: Diffusion in the endoplasmic reticulum of an aquaporin-2 mutant causing human nephrogenic diabetes insipidus.

Journal: The Journal of biological chemistry 20010615

Title: Evaluation of monensin and brefeldin A for flow cytometric determination of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha in monocytes.

Journal: Cytometry 20010615

Title: Stimulation of HIV gp120-specific cytolytic T lymphocyte responses in vitro and in vivo using a detoxified pertussis toxin vector.

Journal: AIDS research and human retroviruses 20010610

Title: Characterization of monoclonal antibody fragments produced by plant cells.

Journal: Biotechnology and bioengineering 20010605

Title: Effects of brefeldin-A: potent inhibitor of intracellular protein transport on ultrastructure and resorptive function of cultured osteoclasts.

Journal: The Anatomical record 20010601

Title: Endocytosis of NBD-sphingolipids in neurons: exclusion from degradative compartments and transport to the Golgi complex.

Journal: Traffic (Copenhagen, Denmark) 20010601

Title: Glucosylceramide synthesis inhibitors block pharmacologically induced dispersal of the Golgi and anterograde membrane flow from the endoplasmic reticulum: implication of sphingolipid metabolism in maintenance of the Golgi architecture and anterograde membrane flow.

Journal: Bioscience, biotechnology, and biochemistry 20010601

Title: Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells.

Journal: Archives of toxicology 20010601

Title: Regulation of cAMP-sensitive colonic epithelial Na+ channel in oocyte expression system.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010601

Title: Palmitoylation of caveolin-1 in endothelial cells is post-translational but irreversible.

Journal: The Journal of biological chemistry 20010511

Title: Agonist-dependent delivery of M(2) muscarinic acetylcholine receptors to the cell surface after pertussis toxin treatment.

Journal: Molecular pharmacology 20010501

Title: Prolactin signalling to milk protein secretion but not to gene expression depends on the integrity of the Golgi region.

Journal: Journal of cell science 20010501

Title: A ryanodine fluorescent derivative reveals the presence of high-affinity ryanodine binding sites in the Golgi complex of rat sympathetic neurons, with possible functional roles in intracellular Ca(2+) signaling.

Journal: Cellular signalling 20010501

Title: Macrophages present exogenous antigens by class I major histocompatibility complex molecules via a secretory pathway as a consequence of interferon-gamma activation.

Journal: Immunology 20010501

Title: Unique biochemical nature of carp retinol-binding protein. N-linked glycosylation and uncleavable NH2-terminal signal peptide.

Journal: The Journal of biological chemistry 20010427

Title: Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides.

Journal: Biochemistry 20010424

Title: Basic fibroblast growth factor-induced proliferation of primary astrocytes. evidence for the involvement of sphingomyelin biosynthesis.

Journal: The Journal of biological chemistry 20010420

Title: Down-regulation of cell surface insulin receptors by sarco(endo)plasmic reticulum Ca2+-ATPase inhibitor in adrenal chromaffin cells.

Journal: Brain research 20010413

Title: Heterogeneous increases of cytoplasmic calcium: distinct effects on down-regulation of cell surface sodium channels and sodium channel subunit mRNA levels.

Journal: British journal of pharmacology 20010401

Title: High glucose concentration favors the selective secretion of islet amyloid polypeptide through a constitutive secretory pathway in human pancreatic islets.

Journal: Pancreas 20010401

Title: Cell wall deposition during morphogenesis in fucoid algae.

Journal: Planta 20010401

Title: Cell volume-induced changes in K+ transport across the rat colon.

Journal: Acta physiologica Scandinavica 20010401

Title: Identification of a novel thioredoxin-related transmembrane protein.

Journal: The Journal of biological chemistry 20010330

Title: An interaction between ricin and calreticulin that may have implications for toxin trafficking.

Journal: The Journal of biological chemistry 20010309

Title: Functional integrity of the vesicle transporting machinery is required for complete activation of cFTR expressed in xenopus laevis oocytes.

Journal: Pflugers Archiv : European journal of physiology 20010301

Title: Mutations of the C-terminal end of cathepsin K affect proenzyme secretion and intracellular maturation.

Journal: Biochemical and biophysical research communications 20010223

Title: Arachidonyltrifluoromethy ketone, a phospholipase A(2) antagonist, induces dispersal of both Golgi stack- and trans Golgi network-resident proteins throughout the cytoplasm.

Journal: Biochemical and biophysical research communications 20010223

Title: TIP47 associates with lipid droplets.

Journal: The Journal of biological chemistry 20010216

Title: The precursor but not the mature form of IL1alpha blocks the release of FGF1 in response to heat shock.

Journal: The Journal of biological chemistry 20010216

Title: Flow cytometric analysis of cytokine production by normal human peripheral blood dendritic cells and monocytes: comparative analysis of different stimuli, secretion-blocking agents and incubation periods.

Journal: Cytometry 20010215

Title: Recycling of the insulin-sensitive glucose transporter GLUT4. Access of surface internalized GLUT4 molecules to the perinuclear storage compartment is mediated by the Phe5-Gln6-Gln7-Ile8 motif.

Journal: The Journal of biological chemistry 20010202

Title: The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts.

Journal: The Journal of bone and joint surgery. American volume 20010201

Title: A study of the protein secretory pathway of Aspergillus niger using a glucoamylase-GFP fusion protein.

Journal: Fungal genetics and biology : FG & B 20010201

Title: Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport.

Journal: Yeast (Chichester, England) 20010130

Title: Group IIA and group V secretory phospholipase A(2): quantitative analysis of expression and secretion and determination of the localization and routing in rat mesangial cells.

Journal: Biochimica et biophysica acta 20010115

Title: Acquisition of Lubrol insolubility, a common step for growth hormone and prolactin in the secretory pathway of neuroendocrine cells.

Journal: The Journal of biological chemistry 20010105

Title: Effect of brefeldin A on melatonin secretion of chick pineal cells.

Journal: Journal of biochemistry 20010101

Title: Coordination of microtubules and the actin cytoskeleton by the Rho effector mDia1.

Journal: Nature cell biology 20010101

Title: Involvement of the secretory pathway for AMPA receptors in NMDA-induced potentiation in hippocampus.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010101

Title: Functional analysis of ADP-ribosylation factor (ARF) guanine nucleotide exchange factors Gea1p and Gea2p in yeast.

Journal: Methods in enzymology 20010101

Title: Localization of the GLUT1 glucose transporter to brefeldin A-sensitive vesicles of differentiated CIT3 mouse mammary epithelial cells.

Journal: Cell biology international 20010101

Title: Molecular and cellular mechanisms of adipose secretion: comparison of leptin and angiotensinogen.

Journal: Journal of cellular biochemistry 20010101

Title: [Effect of elastin peptides on the production of matrix metalloproteinase 2 by human skin fibroblasts in culture].

Journal: Journal de la Societe de biologie 20010101

Title: Tunicamycin and Brefeldin A induce in plant cells a programmed cell death showing apoptotic features.

Journal: Protoplasma 20010101

Title: Strategies for enhancing monoclonal antibody accumulation in plant cell and organ cultures.

Journal: Biotechnology progress 20010101

Title: Gap junction assembly: multiple connexin fluorophores identify complex trafficking pathways.

Journal: Cell communication & adhesion 20010101

Title: Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion.

Journal: Gastroenterology 20000901

Title: ADP-ribosylation factor 6 as a target of guanine nucleotide exchange factor GRP1.

Journal: The Journal of biological chemistry 19990917

Title: Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2.

Journal: Experimental cell research 19981125

Title: Structural requirements for the ectodomain cleavage of human cell surface macrophage colony-stimulating factor.

Journal: The Journal of biological chemistry 19960705

Title: Beta 1- and beta 3-class integrins mediate fibronectin binding activity at the surface of developing mouse peri-implantation blastocysts. Regulation by ligand-induced mobilization of stored receptor.

Journal: The Journal of biological chemistry 19950512

Title: Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.

Journal: The Journal of biological chemistry 19910915

Title: Brefeldin A inhibits the processing and secretion of envelope glycoproteins of human immunodeficiency virus type 1.

Journal: AIDS research and human retroviruses 19910801

Title: Alvarez C, et al. Brefeldin A (BFA) disrupts the organization of the microtubule and the actin cytoskeletons. Eur J Cell Biol. 1999 Jan;78(1):1-14.

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Title: Yu C, et al. Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell. 2015 Feb 5;16(2):142-7.

Title: Nozawa N, et al. Subcellular localization of herpes simplex virus type 1 UL51 protein and role of palmitoylation in Golgi apparatus targeting. J Virol. 2003 Mar;77(5):3204-16.

Title: Jensen HL, Rygaard J, Norrild B. A time-related study of Brefeldin A effects in HSV-1 infected cultured human fibroblasts. APMIS. 1995;103(7-8):530-539. doi:10.1111/j.1699-0463.1995.tb01402.x

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Tags:20350-15-6 Molecular Formula|20350-15-6 MDL|20350-15-6 SMILES|20350-15-6 Brefeldin a