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21187-98-4,MFCD00409893
Catalog No.:AA00I3Z1

21187-98-4 | 1-[(4-methylbenzene)sulfonyl]-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea

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1mg
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$6.00   $4.00
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1g
98%
in stock  
$8.00   $6.00
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5g
98%
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$12.00   $8.00
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25g
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100g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I3Z1
Chemical Name:
1-[(4-methylbenzene)sulfonyl]-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea
CAS Number:
21187-98-4
Molecular Formula:
C15H21N3O3S
Molecular Weight:
323.4105
MDL Number:
MFCD00409893
SMILES:
O=C(NS(=O)(=O)c1ccc(cc1)C)NN1CC2C(C1)CCC2
NSC Number:
758673
Properties
Computed Properties
 
Complexity:
497  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
2  
XLogP3:
1.5  

Literature

Title: Insulinotropic action of 2, 4-dinitroanilino-benzoic acid through the attenuation of pancreatic beta-cell lesions in diabetic rats.

Journal: Chemico-biological interactions 20170801

Title: In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis.

Journal: Chemico-biological interactions 20151005

Title: A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20140101

Title: Association of KCNJ11 E23K gene polymorphism with hypoglycemia in sulfonylurea-treated type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20121001

Title: Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death.

Journal: Basic & clinical pharmacology & toxicology 20121001

Title: Fraction SX of maitake mushroom favorably influences blood glucose levels and blood pressure in streptozotocin-induced diabetic rats.

Journal: Journal of medicinal food 20121001

Title: Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats.

Journal: European journal of pharmacology 20120905

Title: Development of novel gastroretentive floating particulate drug delivery system of gliclazide.

Journal: Current drug delivery 20120901

Title: Protective effect of gliclazide on diabetic peripheral neuropathy through Drp-1 mediated-oxidative stress and apoptosis.

Journal: Neuroscience letters 20120808

Title: Simultaneous determination of lercanidipine, benazepril and benazeprilat in plasma by LC-MS/MS and its application to a toxicokinetics study.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120615

Title: Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20120601

Title: Physicochemical investigations and stability studies of amorphous gliclazide.

Journal: AAPS PharmSciTech 20120601

Title: Patient socioeconomic determinants of the choice of generic versus brand name drugs in the context of a reference price system: evidence from Belgian prescription data.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20120601

Title: Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes.

Journal: Nutrition research (New York, N.Y.) 20120601

Title: Adulteration of herbal antidiabetic products with undeclared pharmaceuticals: a case series in Hong Kong.

Journal: British journal of clinical pharmacology 20120501

Title: Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells.

Journal: Molecular biology reports 20120501

Title: Sitagliptin add-on to low dosage sulphonylureas: efficacy and safety of combination therapy on glycaemic control and insulin secretion capacity in type 2 diabetes.

Journal: International journal of clinical practice 20120501

Title: Differential effects of sulfonylurea derivatives on vascular ATP-sensitive potassium channels.

Journal: European journal of pharmacology 20120415

Title: Design, synthesis and characterization of zinc-3 hydroxy flavone, a novel zinc metallo complex for the treatment of experimental diabetes in rats.

Journal: European journal of pharmacology 20120405

Title: Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: in vitro-in vivo evaluation.

Journal: Drug delivery 20120401

Title: KCNJ11 gene E23K variant and therapeutic response to sulfonylureas.

Journal: European journal of internal medicine 20120401

Title: Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats.

Journal: Behavioural pharmacology 20120401

Title: Determination of alamifovir disoproxil fumarate and its active metabolite 602076 in rat plasma by LC-MS/MS: application to a pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20120305

Title: Antidiabetic activity of gossypin, a pentahydroxyflavone glucoside, in streptozotocin-induced experimental diabetes in rats.

Journal: Journal of diabetes 20120301

Title: Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.

Journal: Pharmacogenetics and genomics 20120301

Title: Variations in tissue selectivity amongst insulin secretagogues: a systematic review.

Journal: Diabetes, obesity & metabolism 20120201

Title: Gliclazide impurity F: N-[(perhydro-cyclo-penta-[c]pyrrol-2-yl)amino-carbon-yl]-o-toluene-sulfonamide.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Glycaemic control and cost analysis when changing from gliclazide co-administered with metformin to pre-combined glibenclamide-metformin tablets in type 2 diabetes mellitus.

Journal: The Medical journal of Malaysia 20120201

Title: Effects of pioglitazone add-on to gliclazide and metformin on glycemic control in patients with type 2 diabetes.

Journal: Endocrine research 20120101

Title: Treating diabetes today: a matter of selectivity of sulphonylureas.

Journal: Diabetes, obesity & metabolism 20120101

Title: Treating diabetes today with gliclazide MR: a matter of numbers.

Journal: Diabetes, obesity & metabolism 20120101

Title: Development and validation of a repharsed phase- HPLC method for simultaneous determination of rosiglitazone and glimepiride in combined dosage forms and human plasma.

Journal: Chemistry Central journal 20120101

Title: Protective effects of beta glucan and gliclazide on brain tissue and sciatic nerve of diabetic rats induced by streptozosin.

Journal: Experimental diabetes research 20120101

Title: Sitagliptin in glutamic acid decarboxylase antibody-positive diabetes mellitus.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20120101

Title: Gliclazide does not fully prevent 2-deoxy-D-ribose-induced oxidative damage because it does not restore glutathione content in a pancreatic β-cell line.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Quality and safety of medication use in primary care: consensus validation of a new set of explicit medication assessment criteria and prioritisation of topics for improvement.

Journal: BMC clinical pharmacology 20120101

Title: Evaluation of the effects of glimepiride (Amaryl) and repaglinide (novoNorm) on atherosclerosis progression in high cholesterol-fed male rabbits.

Journal: Journal of cardiovascular disease research 20120101

Title: Management of diabetes mellitus: could simultaneous targeting of hyperglycemia and oxidative stress be a better panacea?

Journal: International journal of molecular sciences 20120101

Title: Factors contributing to non-compliance among diabetics attending primary health centers in the Al Hasa district of Saudi Arabia.

Journal: Journal of family & community medicine 20120101

Title: Performance scores in general practice: a comparison between the clinical versus medication-based approach to identify target populations.

Journal: PloS one 20120101

Title: Antidiabetic effect of S-allylcysteine: effect on thyroid hormone and circulatory antioxidant system in experimental diabetic rats.

Journal: Journal of diabetes and its complications 20120101

Title: [Diabetes mellitus and chronic kideny disease: modern diagnostics and treatment].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101

Title: [Prevalence of diabetes mellitus in geriatric patients in nursing homes of Cádiz. Diagerca study].

Journal: Revista espanola de geriatria y gerontologia 20120101

Title: Quercetin and epigallocatechin gallate induce in vitro a dose-dependent stiffening and hyperpolarizing effect on the cell membrane of human mononuclear blood cells.

Journal: International journal of molecular sciences 20120101

Title: Efficacy of various antidiabetic agents as add-on treatments to metformin in type 2 diabetes mellitus: systematic review and meta-analysis.

Journal: ISRN endocrinology 20120101

Title: Red carpeting the newer antidiabetics.

Journal: Journal of pharmacology & pharmacotherapeutics 20120101

Title: Robust optimization of alginate-Carbopol 940 bead formulations.

Journal: TheScientificWorldJournal 20120101

Title: The management of type 2 diabetic patients with hypoglycaemic agents.

Journal: ISRN endocrinology 20120101

Title: The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study.

Journal: BMJ (Clinical research ed.) 20120101

Title: Clinical features and treatment of maturity onset diabetes of the young (MODY).

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20120101

Title: Pharmacological approaches to the management of type 2 diabetes in fasting adults during Ramadan.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20120101

Title: Evidence to support the use of vildagliptin monotherapy in the treatment of type 2 diabetes mellitus.

Journal: Vascular health and risk management 20120101

Title: Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity.

Journal: Journal of Ayurveda and integrative medicine 20120101

Title: Using highly sensitive C-reactive protein measurement to diagnose MODY in a family with suspected type 2 diabetes.

Journal: BMJ case reports 20120101

Title: Role of oral hypoglycemic agents in the management of type 2 diabetes mellitus during Ramadan.

Journal: Indian journal of endocrinology and metabolism 20120101

Title: Bioequivalence study of modified-release gliclazide tablets in healthy volunteers.

Journal: ISRN pharmacology 20120101

Title: Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients.

Journal: Evidence-based complementary and alternative medicine : eCAM 20120101

Title: Mild hypoglycaemic attacks induced by sulphonylureas related to CYP2C9, CYP2C19 and CYP2C8 polymorphisms in routine clinical setting.

Journal: European journal of clinical pharmacology 20111201

Title: Does glycemic control offer similar benefits among patients with diabetes in different regions of the world? Results from the ADVANCE trial.

Journal: Diabetes care 20111201

Title: Development, optimization, and anti-diabetic activity of gliclazide-loaded alginate-methyl cellulose mucoadhesive microcapsules.

Journal: AAPS PharmSciTech 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Epidemiology of micro- and macrovascular complications of type 2 diabetes in Korea.

Journal: Diabetes & metabolism journal 20111201

Title: [Incretin-based therapy for treating patients with type 2 diabetes].

Journal: Orvosi hetilap 20111127

Title: High-performance affinity chromatography and the analysis of drug interactions with modified proteins: binding of gliclazide with glycated human serum albumin.

Journal: Analytical and bioanalytical chemistry 20111101

Title: The incidence of hypoglycaemia in Muslim patients with type 2 diabetes treated with sitagliptin or a sulphonylurea during Ramadan: a randomised trial.

Journal: International journal of clinical practice 20111101

Title: Antidiabetic activity of methanolic bark extract of Albizia odoratissima Benth. in alloxan induced diabetic albino mice.

Journal: Asian Pacific journal of tropical medicine 20111101

Title: [Hypoglycemia].

Journal: Praxis 20111019

Title: The discovery of LOX-1, its ligands and clinical significance.

Journal: Cardiovascular drugs and therapy 20111001

Title: Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failure.

Journal: Diabetes research and clinical practice 20111001

Title: Effect of binary and ternary solid dispersions on the in vitro dissolution and in-situ rabbit intestinal absorption of gliclazide.

Journal: Pakistan journal of pharmaceutical sciences 20111001

Title: Comparison of vildagliptin-metformin and glimepiride-metformin treatments in type 2 diabetic patients.

Journal: Diabetes & metabolism journal 20111001

Title: Assessing the influences on therapeutic intensification in type 2 diabetes mellitus according to career stage.

Journal: Diabetes research and clinical practice 20110901

Title: Dissolution rate enhancement of gliclazide by ordered mixing.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20110901

Title: Antidiabetic and antioxidant potentials of Euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats.

Journal: General physiology and biophysics 20110901

Title: Enhanced glycemic control with combination therapy for type 2 diabetes in primary care.

Journal: Diabetes therapy : research, treatment and education of diabetes and related disorders 20110901

Title: Mortality and cardiovascular risk associated with different insulin secretagogues compared with metformin in type 2 diabetes, with or without a previous myocardial infarction: a nationwide study.

Journal: European heart journal 20110801

Title: Genetic risk factors for type 2 diabetes mellitus and response to sulfonylurea treatment.

Journal: Pharmacogenetics and genomics 20110801

Title: Effects of Sulfonylureas on Peroxisome Proliferator-Activated Receptor γ Activity and on Glucose Uptake by Thiazolidinediones.

Journal: Diabetes & metabolism journal 20110801

Title: Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling.

Journal: Biochimica et biophysica acta 20110701

Title: AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study.

Journal: Diabetologia 20110701

Title: Intensive glucose control and risk of cancer in patients with type 2 diabetes.

Journal: Diabetologia 20110701

Title: Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study.

Journal: Current medical research and opinion 20110701

Title: Formulation and evaluation of Ficus glomerata mucilage sustained release matrix tablets of gliclazide.

Journal: Pakistan journal of pharmaceutical sciences 20110701

Title: Pharmacokinetic-pharmacodynamic equivalence of three gliclazide formulations in healthy human male subjects.

Journal: International journal of clinical pharmacology and therapeutics 20110701

Title: Cadmium telluride nanocrystals as luminescent sensitizers in flow analysis.

Journal: Talanta 20110615

Title: Reduced catalytic activity of human CYP2C9 natural alleles for gliclazide: molecular dynamics simulation and docking studies.

Journal: Biochimie 20110601

Title: Effects of gliclazide on endothelial function in patients with newly diagnosed type 2 diabetes.

Journal: European journal of pharmacology 20110601

Title: Hypoglycaemia in sulphonylurea-treated subjects with type 2 diabetes undergoing Ramadan fasting: a five-country observational study.

Journal: Current medical research and opinion 20110601

Title: Assessing the association of pioglitazone use and bladder cancer through drug adverse event reporting.

Journal: Diabetes care 20110601

Title: Insulin concerns and promises.

Journal: Diabetes care 20110601

Title: Diagnosis in diabetes: does it matter?

Journal: The journal of the Royal College of Physicians of Edinburgh 20110601

Title: Retrospective analysis on the efficacy, safety and treatment failure group of sitagliptin for mean 10-month duration.

Journal: Diabetes & metabolism journal 20110601

Title: Molecular dynamics simulation of drug uptake by polymer.

Journal: Journal of molecular modeling 20110501

Title: Diabetes and the risk of developing Parkinson's disease in Denmark.

Journal: Diabetes care 20110501

Title: Persistently autoantibody negative (PAN) type 1 diabetes mellitus in children.

Journal: Pediatric diabetes 20110501

Title: Minimizing the risk of hypoglycemia with vildagliptin: Clinical experience, mechanistic basis, and importance in type 2 diabetes management.

Journal: Diabetes therapy : research, treatment and education of diabetes and related disorders 20110501

Title: Simultaneous identification and validated quantification of 11 oral hypoglycaemic drugs in plasma by electrospray ionisation liquid chromatography-mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20110401

Title: Increasing trend in the number of severe hypoglycemia patients in Korea.

Journal: Diabetes & metabolism journal 20110401

Title: In vitro-in vivo correlation for gliclazide immediate-release tablets based on mechanistic absorption simulation.

Journal: AAPS PharmSciTech 20110301

Title: Insulin and metformin may prevent renal injury in young type 2 diabetic Goto-Kakizaki rats.

Journal: European journal of pharmacology 20110225

Title: Comparison of two sulfonylureas with high and low myocardial K(ATP) channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes.

Journal: Diabetologia 20110201

Title: Successful transfer to sulfonylurea therapy in an infant with developmental delay, epilepsy and neonatal diabetes (DEND) syndrome and a novel ABCC8 gene mutation.

Journal: Diabetologia 20110201

Title: Design and development of gliclazide-loaded chitosan microparticles for oral sustained drug delivery: in-vitro/in-vivo evaluation.

Journal: The Journal of pharmacy and pharmacology 20110201

Title: Structured self-monitoring of blood glucose significantly reduces A1C levels in poorly controlled, noninsulin-treated type 2 diabetes: results from the Structured Testing Program study.

Journal: Diabetes care 20110201

Title: Warfarin-induced eosinophilic pleural effusion.

Journal: Korean circulation journal 20110201

Title: Effect of pioglitazone on serum concentrations of osteoprotegerin in patients with type 2 diabetes mellitus.

Journal: European journal of endocrinology 20110101

Title: Design and development of gliclazide-loaded chitosan for oral sustained drug delivery: in vitro/in vivo evaluation.

Journal: Journal of microencapsulation 20110101

Title: Understanding diabetes in patients with HIV/AIDS.

Journal: Diabetology & metabolic syndrome 20110101

Title: Response to oral gliclazide in a pre-pubertal child with hepatic nuclear factor-1 alpha maturity onset diabetes of the young.

Journal: Annals of Saudi medicine 20110101

Title: Management of cardiovascular risk factors with pioglitazone combination therapies in type 2 diabetes: an observational cohort study.

Journal: Cardiovascular diabetology 20110101

Title: Combination of Medicinal Herbs KIOM-79 Reduces Advanced Glycation End Product Accumulation and the Expression of Inflammatory Factors in the Aorta of Zucker Diabetic Fatty Rats.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Effect of repaglinide and gliclazide on glycaemic control, early-phase insulin secretion and lipid profiles in.

Journal: Chinese medical journal 20110101

Title: Assessing the general safety and tolerability of vildagliptin: value of pooled analyses from a large safety database versus evaluation of individual studies.

Journal: Vascular health and risk management 20110101

Title: Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Effects of zinc and multimineral vitamin supplementation on glycemic and lipid control in adult diabetes.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Phase I Clinical Study of the Dietary Supplement, Agaricus blazei Murill, in Cancer Patients in Remission.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Antidiabetic Activities of Abutilon indicum (L.) Sweet Are Mediated by Enhancement of Adipocyte Differentiation and Activation of the GLUT1 Promoter.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Collagenofibrotic glomerulopathy - Case report with review of literature.

Journal: Indian journal of nephrology 20110101

Title: Dyslipidaemia of obesity, metabolic syndrome and type 2 diabetes mellitus: the case for residual risk reduction after statin treatment.

Journal: The open cardiovascular medicine journal 20110101

Title: Diabetes and Ramadan: an update on use of glycemic therapies during fasting.

Journal: Annals of Saudi medicine 20110101

Title: The study of aqueous extract of Ficus religiosa Linn. on cytokine TNF-α in type 2 diabetic rats.

Journal: Pharmacognosy research 20110101

Title: Management of hyperglycemia in geriatric patients with diabetes mellitus: South Asian consensus guidelines.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: From theory to clinical practice in the use of GLP-1 receptor agonists and DPP-4 inhibitors therapy.

Journal: Experimental diabetes research 20110101

Title: Antidiabetic pharmacotherapy and anamnestic hypoglycemia in a large cohort of type 2 diabetic patients--an analysis of the DiaRegis registry.

Journal: Cardiovascular diabetology 20110101

Title: Effects of improving glycemic control with insulin on leptin, adiponectin, ghrelin and neuropeptidey levels in patients with type 2 diabetes mellitus: a pilot study.

Journal: The open cardiovascular medicine journal 20110101

Title: Diabetic nephropathy - Epidemiology in Asia and the current state of treatment.

Journal: Indian journal of nephrology 20110101

Title: Effects of a moderate low-carbohydrate diet on preferential abdominal fat loss and cardiovascular risk factors in patients with type 2 diabetes.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20110101

Title: Pharmacogenetics of oral antidiabetic treatment.

Journal: Bratislavske lekarske listy 20110101

Title: An evaluation of the use of smartphones to communicate between clinicians: a mixed-methods study.

Journal: Journal of medical Internet research 20110101

Title: Type 2 Diabetes Mellitus-Induced Hyperglycemia in Patients with NAFLD and Normal LFTs: Relationship to Lipid Profile, Oxidative Stress and Pro-Inflammatory Cytokines.

Journal: Scientia pharmaceutica 20110101

Title: The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation.

Journal: Advances in pharmacological sciences 20110101

Title: Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease.

Journal: Cardiovascular diabetology 20110101

Title: Medicinal chemistry of the anti-diabetic effects of momordica charantia: active constituents and modes of actions.

Journal: The open medicinal chemistry journal 20110101

Title: Spectrophotometric determination of tizanidine and orphenadrine via ion pair complex formation using eosin Y.

Journal: Chemistry Central journal 20110101

Title: Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion.

Journal: Chinese medicine 20110101

Title: Development and validation of stability indicating method for determination of sertraline following ICH guidlines and its determination in pharmaceuticals and biological fluids.

Journal: Chemistry Central journal 20110101

Title: Ramsay Hunt syndrome with unilateral polyneuropathy involving cranial nerves V, VII, VIII, and XII in a diabetic patient.

Journal: Quintessence international (Berlin, Germany : 1985) 20110101

Title: Ramadan and diabetes: As-Saum (The fasting).

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Pioglitazone: Indian perspective.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Choosing a gliptin.

Journal: Indian journal of endocrinology and metabolism 20110101

Title: Second-line therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy: a systematic review and mixed-treatment comparison meta-analysis.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20110101

Title: Eudragit nanoparticles containing genistein: formulation, development, and bioavailability assessment.

Journal: International journal of nanomedicine 20110101

Title: A cluster randomised trial of educational messages to improve the primary care of diabetes.

Journal: Implementation science : IS 20110101

Title: Metabolomics reveals reduction of metabolic oxidation in women with polycystic ovary syndrome after pioglitazone-flutamide-metformin polytherapy.

Journal: PloS one 20110101

Title: Catastrophic complication - Bezold-Jarisch reflex: Case series.

Journal: Indian journal of anaesthesia 20110101

Title: Preparation and characterization of pioglitazone cyclodextrin inclusion complexes.

Journal: Journal of young pharmacists : JYP 20110101

Title: [Comparative characteristics of antioxidant properties of hypoglycemic agents diabenol and gliclazide].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101

Title: Estimation of Embelin in Embelia tsjeriam-cottam Fruits by HPLC to Standardize Harvesting Time.

Journal: Indian journal of pharmaceutical sciences 20110101

Title: Separation and quantification of eight antidiabetic drugs on a high-performance liquid chromatography: its application to human plasma assay.

Journal: ISRN pharmaceutics 20110101

Title: Remnant B-cell-stimulative and anti-oxidative effects of Persea americana fruit extract studied in rats introduced into streptozotocin - induced hyperglycaemic state.

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM 20110101

Title: Design and evaluation of a novel formulation prediction system.

Journal: International journal of pharmaceutics 20101215

Title: Antidiabetic effect of S-allylcysteine: Effect on plasma and tissue glycoproteins in experimental diabetes.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20101201

Title: Smoking and risk for diabetes incidence and mortality in Korean men and women.

Journal: Diabetes care 20101201

Title: Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20101201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Hydrochloride pioglitazone decreases urinary cytokines excretion in type 2 diabetes.

Journal: Clinical endocrinology 20101201

Title: Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry.

Journal: Diabetes research and clinical practice 20101201

Title: ABCC8 polymorphism (Ser1369Ala): influence on severe hypoglycemia due to sulfonylureas.

Journal: Pharmacogenomics 20101201

Title: The study of aqueous extract of Pterocarpus marsupium Roxb. on cytokine TNF-α in type 2 diabetic rats.

Journal: Indian journal of pharmacology 20101201

Title: Erectile dysfunction and later cardiovascular disease in men with type 2 diabetes: prospective cohort study based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) trial.

Journal: Journal of the American College of Cardiology 20101130

Title: Chromatographic studies of changes in binding of sulfonylurea drugs to human serum albumin due to glycation and fatty acids.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101115

Title: Vildagliptin: a review of its use in type 2 diabetes mellitus.

Journal: Drugs 20101112

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Diabetes & coronary heart disease: current perspectives.

Journal: The Indian journal of medical research 20101101

Title: Severe hypoglycemia and risks of vascular events and death.

Journal: The New England journal of medicine 20101007

Title: Impact of D-pinitol on the attenuation of proinflammatory cytokines, hyperglycemia-mediated oxidative stress and protection of kidney tissue ultrastructure in streptozotocin-induced diabetic rats.

Journal: Chemico-biological interactions 20101006

Title: Effects of metformin plus gliclazide compared with metformin alone on circulating endothelial progenitor cell in type 2 diabetic patients.

Journal: Endocrine 20101001

Title: Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20100901

Title: Genetic determinants predicting efficacy of glucose-lowering drugs?: a long way to go ..

Journal: Diabetes care 20100901

Title: Physicochemical characterization of gliclazide-macrogol solid dispersion and tablets based on optimized dispersion.

Journal: Drug development and industrial pharmacy 20100801

Title: The effect of oral antidiabetic agents on A1C levels: a systematic review and meta-analysis.

Journal: Diabetes care 20100801

Title: The efficacy of lowering glycated haemoglobin with a gliclazide modified release-based intensive glucose lowering regimen in the ADVANCE trial.

Journal: Diabetes research and clinical practice 20100801

Title: Recommendations for management of diabetes during Ramadan: update 2010.

Journal: Diabetes care 20100801

Title: [Effect of hypoglycemic drugs on hemostasis].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20100801

Title: Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats.

Journal: Chemico-biological interactions 20100730

Title: Pioglitazone decreases plasma cholesteryl ester transfer protein mass, associated with a decrease in hepatic triglyceride content, in patients with type 2 diabetes.

Journal: Diabetes care 20100701

Title: Preparation and in vitro evaluation of gliclazide sustained-release matrix pellets: formulation and storage stability.

Journal: Drug development and industrial pharmacy 20100701

Title: Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis.

Journal: Diabetologia 20100701

Title: Maintenance of glycaemic control with the evening administration of a long acting sulphonylurea in male type 2 diabetic patients undertaking the Ramadan fast.

Journal: International journal of clinical practice 20100701

Title: Management of high blood pressure in type 2 diabetes: perindopril/indapamide fixed-dose combination and the ADVANCE trial [corrected].

Journal: Expert opinion on pharmacotherapy 20100701

Title: Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100611

Title: The risk of overall mortality in patients with type 2 diabetes receiving glipizide, glyburide, or glimepiride monotherapy: a retrospective analysis.

Journal: Diabetes care 20100601

Title: Sitagliptin: review of preclinical and clinical data regarding incidence of pancreatitis.

Journal: International journal of clinical practice 20100601

Title: Gliclazide microcrystals prepared by two methods of in situ micronization: pharmacokinetic studies in diabetic and normal rats.

Journal: AAPS PharmSciTech 20100601

Title: Neuropathy, retinopathy, and glucose-lowering treatments.

Journal: Diabetes care 20100601

Title: Effect of gliclazide on nucleotide excision repair (NER) and non-homologous DNA end joining (NHEJ) in normal and cancer cells.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

Title: Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics and pharmacodynamics of gliclazide in healthy Chinese Han volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20100601

Title: Three novel mutations in MODY and its phenotype in three different Czech families.

Journal: Diabetes research and clinical practice 20100501

Title: Associations of hyperglycemia and insulin usage with the risk of cancer in type 2 diabetes: the Hong Kong diabetes registry.

Journal: Diabetes 20100501

Title: Exercise training ameliorates the effects of rosiglitazone on traditional and novel cardiovascular risk factors in patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20100401

Title: Effects of short-term therapy with different insulin secretagogues on glucose metabolism, lipid parameters and oxidative stress in newly diagnosed Type 2 Diabetes Mellitus.

Journal: Diabetes research and clinical practice 20100401

Title: Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin.

Journal: Diabetes 20100401

Title: Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial.

Journal: European heart journal 20100401

Title: Dipeptidyl peptidase-IV inhibitors are efficient adjunct therapy in HNF1A maturity-onset diabetes of the young patients--report of two cases.

Journal: Diabetes technology & therapeutics 20100401

Title: Importance of blood pressure lowering in type 2 diabetes: focus on ADVANCE.

Journal: Journal of cardiovascular pharmacology 20100401

Title: Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid-chromatographic determination of anti-diabetic drugs.

Journal: Journal of pharmaceutical and biomedical analysis 20100311

Title: Insulin releasing and alpha-glucosidase inhibitory activity of ethyl acetate fraction of Acorus calamus in vitro and in vivo.

Journal: Journal of ethnopharmacology 20100302

Title: CD14+ monocytes are vulnerable and functionally impaired under endoplasmic reticulum stress in patients with type 2 diabetes.

Journal: Diabetes 20100301

Title: Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1{alpha}/Mitofusin-2 regulatory pathway in response to physical activity.

Journal: Diabetes care 20100301

Title: Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Journal: Journal of thrombosis and haemostasis : JTH 20100301

Title: Comparison of insulin sensitivity, glucose sensitivity, and first phase insulin secretion in patients treated with repaglinide or gliclazide.

Journal: Archives of pharmacal research 20100301

Title: Cardioprotection and ageing.

Journal: Korean journal of anesthesiology 20100301

Title: Comparison of metformin, gliclazide MR and rosiglitazone in monotherapy and in combination for type 2 diabetes.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20100301

Title: A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20100301

Title: Evaluation of different tests based on observations for external model evaluation of population analyses.

Journal: Journal of pharmacokinetics and pharmacodynamics 20100201

Title: Event rates, hospital utilization, and costs associated with major complications of diabetes: a multicountry comparative analysis.

Journal: PLoS medicine 20100201

Title: Regulation of glucose control in people with type 2 diabetes: a review and consensus.

Journal: Korean diabetes journal 20100201

Title: The devil is in the detail - a multifactorial intervention to reduce blood pressure in co-existing diabetes and chronic kidney disease: a single blind, randomized controlled trial.

Journal: BMC family practice 20100101

Title: Differential DNA methylation correlates with differential expression of angiogenic factors in human heart failure.

Journal: PloS one 20100101

Title: Evaluation of efficacy and tolerability of gliclazide and metformin combination: a multicentric study in patients with type 2 diabetes mellitus uncontrolled on monotherapy with sulfonylurea or metformin.

Journal: American journal of therapeutics 20100101

Title: Statin-associated weakness in myasthenia gravis: a case report.

Journal: Journal of medical case reports 20100101

Title: Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis.

Journal: Mediators of inflammation 20100101

Title: Present status of sulfonylurea treatment for type 2 diabetes in Japan: second report of a cross-sectional survey of 15,652 patients.

Journal: Endocrine journal 20100101

Title: JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial.

Journal: Trials 20100101

Title: [The effects of early intensive therapy on islet beta cell function and long-term glycemia control in newly diagnosed type 2 diabetic patients with different fasting plasma glucose levels.].

Journal: Zhonghua nei ke za zhi 20100101

Title: Acute occlusion of the celiac axis and its branches with perforation of gastric fundus and splenic infarction, findings on spiral computed tomography: a case report.

Journal: Cases journal 20100101

Title: Type 2 diabetes: postprandial hyperglycemia and increased cardiovascular risk.

Journal: Vascular health and risk management 20100101

Title: The value of episodic, intensive blood glucose monitoring in non-insulin treated persons with Type 2 Diabetes: design of the Structured Testing Program (STeP) study, a cluster-randomised, clinical trial [NCT00674986].

Journal: BMC family practice 20100101

Title: Algorithm for the treatment of type 2 diabetes: a position statement of Brazilian Diabetes Society.

Journal: Diabetology & metabolic syndrome 20100101

Title: A supercritical fluid chromatography/tandem mass spectrometry method for the simultaneous quantification of metformin and gliclazide in human plasma.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Effect of Agaricus blazei Murill on the pulmonary tissue of animals with streptozotocin-induced diabetes.

Journal: Experimental diabetes research 20100101

Title: Gene activation regresses atherosclerosis, promotes health, and enhances longevity.

Journal: Lipids in health and disease 20100101

Title: Bone events and evolution of biologic markers in Gaucher disease before and during treatment.

Journal: Arthritis research & therapy 20100101

Title: Association of hypoglycemic symptoms with patients' rating of their health-related quality of life state: a cross sectional study.

Journal: Health and quality of life outcomes 20100101

Title: Carotid intima-media thickness in individuals with and without type 2 diabetes: a reproducibility study.

Journal: Cardiovascular diabetology 20100101

Title: Therapies for type 2 diabetes: lowering HbA1c and associated cardiovascular risk factors.

Journal: Cardiovascular diabetology 20100101

Title: [Dynamics of structural-functional parameters of cardiovascular system during use of complex therapy of women with type 2 diabetes mellitus].

Journal: Kardiologiia 20100101

Title: Validated high performance thin layer chromatographic determination and content uniformity test for rosiglitazone in tablets.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Effects of oral glucose-lowering drugs on long term outcomes in patients with diabetes mellitus following myocardial infarction not treated with emergent percutaneous coronary intervention--a retrospective nationwide cohort study.

Journal: Cardiovascular diabetology 20100101

Title: A prospective study of dietary selenium intake and risk of type 2 diabetes.

Journal: BMC public health 20100101

Title: Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment.

Journal: Vascular health and risk management 20100101

Title: Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review.

Journal: Vascular health and risk management 20100101

Title: [Capabilities of hypoglycemic therapy in women with decompensated type 2 diabetes mellitus].

Journal: Terapevticheskii arkhiv 20100101

Title: Prolonged use of ertapenem to treat infected diabetic foot ulcers.

Journal: Case reports in medicine 20100101

Title: Aqueous extract of garcinia indica choisy restores glutathione in type 2 diabetic rats.

Journal: Journal of young pharmacists : JYP 20100101

Title: Pharmacotherapy-Based Problems in the Management of Diabetes Mellitus: Needs Much More to be Done!

Journal: Journal of young pharmacists : JYP 20100101

Title: Lipid control and use of lipid-regulating drugs for prevention of cardiovascular events in Chinese type 2 diabetic patients: a prospective cohort study.

Journal: Cardiovascular diabetology 20100101

Title: Permeability evaluation through chitosan membranes using taguchi design.

Journal: Scientia pharmaceutica 20100101

Title: Drug-drug Interaction between Pravastatin and Gemfibrozil (Antihyperlipidemic) with Gliclazide (Antidiabetic) in Rats.

Journal: Journal of young pharmacists : JYP 20100101

Title: Efficacy of self-monitoring of blood glucose in patients with type 2 diabetes mellitus managed without insulin: a systematic review and meta-analysis.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20100101

Title: Moyamoya syndrome in a known case of pulmonary tuberculosis.

Journal: Journal of neurosciences in rural practice 20100101

Title: Protective role of glibenclamide against nicotinamide-streptozotocin induced nuclear damage in diabetic Wistar rats.

Journal: Journal of pharmacology & pharmacotherapeutics 20100101

Title: Sulphonylureas and cancer: a case-control study.

Journal: Acta diabetologica 20091201

Title: Simultaneous determination of anti-diabetes/anti-obesity drugs by LC/PDA, and targeted analysis of sibutramine analog in dietary supplements by LC/MS/MS.

Journal: Biomedical chromatography : BMC 20091201

Title: Efficacy and safety comparison between the DPP-4 inhibitor vildagliptin and the sulfonylurea gliclazide after two years of monotherapy in drug-naïve patients with type 2 diabetes.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091201

Title: Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis.

Journal: European journal of clinical pharmacology 20091201

Title: Glibenclamide-related excess in total and cardiovascular mortality risks: data from large Ukrainian observational cohort study.

Journal: Diabetes research and clinical practice 20091201

Title: Pharmacokinetics and bioequivalence evaluation of gliclazide/metformin combination tablet and equivalent doses of gliclazide and metformin in healthy Korean subjects.

Journal: International journal of clinical pharmacology and therapeutics 20091201

Title: Recent cardiovascular trials: what are the drivers of benefit and adverse effect?

Journal: Journal of diabetes 20091201

Title: Effects of the dipeptidyl peptidase-IV inhibitor ASP8497 on glucose tolerance in animal models of secondary failure.

Journal: European journal of pharmacology 20091110

Title: Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.

Journal: The Journal of clinical investigation 20091102

Title: Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial.

Journal: Diabetes care 20091101

Title: Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial.

Journal: Diabetologia 20091101

Title: Self-monitoring of blood glucose as part of the integral care of type 2 diabetes.

Journal: Diabetes care 20091101

Title: Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity or mortality? No.

Journal: Diabetes care 20091101

Title: Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity/mortality? Yes.

Journal: Diabetes care 20091101

Title: A summary of the ADVANCE Trial.

Journal: Diabetes care 20091101

Title: Severe neuroglycopaenia secondary to severe hypoglycaemia from serendipitous overdose of gliclazide without adrenergic or autonomic response.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20091101

Title: Effect of gliclazide immobilization into layered double hydroxide on drug release.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091001

Title: Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel.

Journal: Diabetes 20091001

Title: Vildagliptin therapy and hypoglycaemia in Muslim type 2 diabetes patients during Ramadan.

Journal: International journal of clinical practice 20091001

Title: Trace analysis of glyclazide in human plasma at microscale level by mass spectrometry.

Journal: Journal of separation science 20091001

Title: Second-generation sulfonylureas preserve inhibition of mitochondrial permeability transition by the mitochondrial K+(ATP) opener nicorandil in experimental myocardial infarction.

Journal: Shock (Augusta, Ga.) 20090901

Title: Sulfonylureas and prognosis after myocardial infarction in patients with diabetes: a population-based follow-up study.

Journal: Diabetes/metabolism research and reviews 20090901

Title: Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide.

Journal: Diabetes & metabolism 20090901

Title: Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial.

Journal: International journal of clinical practice 20090901

Title: Long-term effects of rosiglitazone on the progressive decline in renal function in patients with type 2 diabetes.

Journal: The Korean journal of internal medicine 20090901

Title: The improvement of hypertension by probiotics: effects on cholesterol, diabetes, renin, and phytoestrogens.

Journal: International journal of molecular sciences 20090901

Title: D-pinitol attenuates the impaired activities of hepatic key enzymes in carbohydrate metabolism of streptozotocin-induced diabetic rats.

Journal: General physiology and biophysics 20090901

Title: Sulphonylurea physicochemical-pharmacokinetic relationships in the pancreas and liver.

Journal: Journal of pharmaceutical sciences 20090801

Title: Antihyperglycemic effects of total flavonoids from Polygonatum odoratum in STZ and alloxan-induced diabetic rats.

Journal: Journal of ethnopharmacology 20090730

Title: Design and synthesis of 3,5-diarylisoxazole derivatives as novel class of anti-hyperglycemic and lipid lowering agents.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Expression of COX-2, NF-kappaB-p65, NF-kappaB-p50 and IKKalpha in malignant and adjacent normal human colorectal tissue.

Journal: British journal of cancer 20090707

Title: Pioglitazone-induced acute rhabdomyolysis.

Journal: Diabetes care 20090701

Title: A rice bran oil diet improves lipid abnormalities and suppress hyperinsulinemic responses in rats with streptozotocin/nicotinamide-induced type 2 diabetes.

Journal: Journal of clinical biochemistry and nutrition 20090701

Title: Synthesis and blood glucose lowering effect of novel pyridazinone substituted benzenesulfonylurea derivatives.

Journal: European journal of medicinal chemistry 20090601

Title: The behavior of Gliclazide in solution and in the solid state: a case of organic compound presenting a solid-solution structure.

Journal: Magnetic resonance in chemistry : MRC 20090601

Title: Physicochemical properties of solid dispersions of gliclazide in polyvinylpyrrolidone K90.

Journal: AAPS PharmSciTech 20090601

Title: Increased carnitine palmitoyl transferase 1 expression and decreased sterol regulatory element-binding protein 1c expression are associated with reduced intramuscular triglyceride accumulation after insulin therapy in high-fat-diet and streptozotocin-induced diabetic rats.

Journal: Metabolism: clinical and experimental 20090601

Title: Genetic architecture of type 2 diabetes: recent progress and clinical implications.

Journal: Diabetes care 20090601

Title: Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats.

Journal: Chemico-biological interactions 20090515

Title: Determination of antihyperglycemic drugs in nanomolar concentration levels by micellar electrokinetic chromatography with non-ionic surfactant.

Journal: Journal of chromatography. A 20090515

Title: The oral anti-diabetic agent, gliclazide, inhibits oxidized LDL-mediated LOX-1 expression, metalloproteinase-9 secretion and apoptosis in human aortic endothelial cells.

Journal: Atherosclerosis 20090501

Title: Sergliflozin etabonate, a selective SGLT2 inhibitor, improves glycemic control in streptozotocin-induced diabetic rats and Zucker fatty rats.

Journal: European journal of pharmacology 20090501

Title: Blood pressure and glucose control in subjects with diabetes: new analyses from ADVANCE.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20090501

Title: In vive effects of gliclazide and metformin on the plasma concentration of caffeine in healthy rats.

Journal: Pakistan journal of biological sciences : PJBS 20090501

Title: [Features of insulin secretion and insulin resistance in newly diagnosed type 2 diabetes of different body mass indices].

Journal: Zhonghua yi xue za zhi 20090428

Title: Overcome side identification in PPOP by making orifices on both layers.

Journal: International journal of pharmaceutics 20090417

Title: Free fatty acid kinetics during long-term treatment with pioglitazone added to sulfonylurea or metformin in Type 2 diabetes.

Journal: Journal of internal medicine 20090401

Title: Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus.

Journal: Diabetes 20090401

Title: Study of the Effect of Panax Ginseng versus Gliclazide on Hyperglycaemia Induced by Dexamethasone in Experimental Animals.

Journal: Sultan Qaboos University medical journal 20090401

Title: Applying the Taguchi design for optimized formulation of sustained release gliclazide chitosan beads: an in vitro/in vivo study.

Journal: AAPS PharmSciTech 20090301

Title: Antidiabetic effects of dipeptidyl peptidase-IV inhibitors and sulfonylureas in streptozotocin-nicotinamide-induced mildly diabetic mice.

Journal: Metabolism: clinical and experimental 20090301

Title: Preparation and characterization of gliclazide-polyethylene glycol 4000 solid dispersions.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20090301

Title: The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study.

Journal: European journal of medicinal chemistry 20090201

Title: Somatostatin secreted by islet delta-cells fulfills multiple roles as a paracrine regulator of islet function.

Journal: Diabetes 20090201

Title: Glucose and pharmacological modulators of ATP-sensitive K+ channels control [Ca2+]c by different mechanisms in isolated mouse alpha-cells.

Journal: Diabetes 20090201

Title: Unexplained severe hypoglycaemia in hospital: a difficult diagnostic challenge.

Journal: British journal of clinical pharmacology 20090201

Title: Treatment of HNF1-alpha MODY with the DPP-4 inhibitor Sitagliptin(1).

Journal: Diabetic medicine : a journal of the British Diabetic Association 20090201

Title: Antioxidant and vascular effects of gliclazide in type 2 diabetic rats fed high-fat diet.

Journal: Physiological research 20090101

Title: Normal insulin response to short-term intense exercise is abolished in Type 2 diabetic patients treated with gliclazide.

Journal: Journal of diabetes and its complications 20090101

Title: Novel 2-aryl-naphtho[1,2-d]oxazole derivatives as potential PTP-1B inhibitors showing antihyperglycemic activities.

Journal: European journal of medicinal chemistry 20090101

Title: Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes.

Journal: Diabetes care 20090101

Title: Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy.

Journal: The Annals of pharmacotherapy 20090101

Title: Competition between COX-2 inhibitors and some other drugs for binding sites on human serum albumin.

Journal: Drug metabolism and drug interactions 20090101

Title: DreamTel; Diabetes risk evaluation and management tele-monitoring study protocol.

Journal: BMC endocrine disorders 20090101

Title: Redefining the role of thiazolidinediones in the management of type 2 diabetes.

Journal: Vascular health and risk management 20090101

Title: Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: [Effect of early insulin therapy on nuclear factor-kappaB inflammatory pathway in liver of diabetic rat].

Journal: Zhonghua nei ke za zhi 20090101

Title: Factors associated with results and conclusions of trials of thiazolidinediones.

Journal: PloS one 20090101

Title: Co-solvent solubilization of some poorly-soluble antidiabetic drugs.

Journal: Pharmaceutical development and technology 20090101

Title: Hypoglycemic herbs and their action mechanisms.

Journal: Chinese medicine 20090101

Title: Rosiglitazone and myocardial infarction in patients previously prescribed metformin.

Journal: PloS one 20090101

Title: Diabetes changes the levels of ionotropic glutamate receptors in the rat retina.

Journal: Molecular vision 20090101

Title: Interactions between herbal medicines and prescribed drugs: an updated systematic review.

Journal: Drugs 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Influence of non-nucleoside reverse transcriptase inhibitors (efavirenz and nevirapine) on the pharmacodynamic activity of gliclazide in animal models.

Journal: Diabetology & metabolic syndrome 20090101

Title: Revisiting clinical trials on glycemic control and cardiovascular risk.

Journal: Diabetology & metabolic syndrome 20090101

Title: Fear of hypoglycaemia: defining a minimum clinically important difference in patients with type 2 diabetes.

Journal: Health and quality of life outcomes 20090101

Title: Cardiotoxicity of verapamil in renal failure: a case report and review of the literature.

Journal: Cases journal 20090101

Title: Persistent orocutaneous and anal fistulae induced by nicorandil: a case report.

Journal: Journal of medical case reports 20090101

Title: Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general practice research database.

Journal: BMJ (Clinical research ed.) 20090101

Title: Idiopathic pulmonary fibrosis associated with pulmonary vein thrombosis: a case report.

Journal: Cases journal 20090101

Title: Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101

Title: [Diabetic edematous maculopathy associated with rosiglitazone treatment: report of a case].

Journal: Bulletin de la Societe belge d'ophtalmologie 20090101

Title: Long-Term Alendronate Use Not without Consequences?

Journal: International journal of rheumatology 20090101

Title: Implication of enterohepatic re-circulation on single dose bioequivalence evaluation of two brands of clonidine hydrochloride tablets in healthy human volunteers.

Journal: Indian journal of pharmaceutical sciences 20090101

Title: Risk management in the treatment of type 2 diabetes with pioglitazone.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20090101

Title: Self-monitoring of blood glucose in noninsulin-treated type 2 diabetes: an overview.

Journal: Diabetes, metabolic syndrome and obesity : targets and therapy 20090101

Title: Setting-up nurse-led pilot clinics for the management of non-communicable diseases at primary health care level in resource-limited settings of Africa.

Journal: The Pan African medical journal 20090101

Title: Short insulin tolerance test can determine the effects of thiazolidinediones treatment in type 2 diabetes.

Journal: Yonsei medical journal 20081231

Title: [Effects of early insulin therapy on nuclear factor kappaB pathway in skeletal muscle of diabetes: experiment with rats].

Journal: Zhonghua yi xue za zhi 20081216

Title: The efficacy of self-monitoring of blood glucose in the management of patients with type 2 diabetes treated with a gliclazide modified release-based regimen. A multicentre, randomized, parallel-group, 6-month evaluation (DINAMIC 1 study).

Journal: Diabetes, obesity & metabolism 20081201

Title: Additive interaction of hyperglycemia and albuminuria on risk of ischemic stroke in type 2 diabetes: Hong Kong Diabetes Registry.

Journal: Diabetes care 20081201

Title: In vitro and in vivo evaluation of a novel push-pull osmotic pump with orifices on both side surfaces.

Journal: Drug development and industrial pharmacy 20081201

Title: Risk of coronary artery disease associated with initial sulphonylurea treatment of patients with type 2 diabetes: a matched case-control study.

Journal: Diabetes research and clinical practice 20081201

Title: Safety and efficacy of nateglinide/metformin combination therapy in the treatment of type 2 diabetes.

Journal: Vascular health and risk management 20081201

Title: Blood glucose levels in patients with metastatic renal cell carcinoma treated with sunitinib.

Journal: British journal of cancer 20081104

Title: Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia: a nested case-control analysis.

Journal: Diabetes care 20081101

Title: Hyperglycaemia secondary to mirtazapine therapy in a 37-year-old man.

Journal: The Australian and New Zealand journal of psychiatry 20081101

Title: Antioxidant effects and insulin resistance improvement of chromium combined with vitamin C and e supplementation for type 2 diabetes mellitus.

Journal: Journal of clinical biochemistry and nutrition 20081101

Title: Severe hyponatremia due to rosiglitazone use in an elderly woman with diabetes mellitus: a rare cause of syndrome of inappropriate antidiuretic hormone secretion.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20081101

Title: Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

Journal: Diabetes care 20081001

Title: Comparison of gliclazide with insulin as initial treatment modality in newly diagnosed type 2 diabetes.

Journal: Diabetes technology & therapeutics 20081001

Title: No need for the needle (at first).

Journal: Diabetes care 20081001

Title: optimization of extended zero-order release gliclazide tablets using D-optimal mixture design.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001

Title: Reversible binding of antidiabetic drugs, repaglinide and gliclazide, with human serum albumin.

Journal: Chemical biology & drug design 20081001

Title: Euscaphic acid, a new hypoglycemic natural product from Folium Eriobotryae.

Journal: Die Pharmazie 20081001

Title: Protective effect of aqueous extract of Embelia ribes Burm fruits in middle cerebral artery occlusion-induced focal cerebral ischemia in rats.

Journal: Indian journal of pharmacology 20081001

Title: Clinical pharmacology.

Journal: Indian journal of pharmacology 20081001

Title: Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats.

Journal: Acta diabetologica 20080901

Title: Pioglitazone decreases fasting and postprandial endogenous glucose production in proportion to decrease in hepatic triglyceride content.

Journal: Diabetes 20080901

Title: Glycemic control in diabetes: a tale of three studies.

Journal: Diabetes care 20080901

Title: Daily blood glucose profiles of glibenclamide and gliclazide taken once or twice daily in elderly type 2 diabetic patients.

Journal: Geriatrics & gerontology international 20080901

Title: Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome.

Journal: Diabetes care 20080801

Title: Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic beta-cell line, MIN6.

Journal: Metabolism: clinical and experimental 20080801

Title: The effect of aqueous extract of Embelia ribes Burm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia.

Journal: Indian journal of pharmacology 20080801

Title: Effects of sulfonylurea drugs on adiponectin production from 3T3-L1 adipocytes: implication of different mechanism from pioglitazone.

Journal: Diabetes research and clinical practice 20080701

Title: Is Ramadan fasting safe in type 2 diabetic patients in view of the lack of significant effect of fasting on clinical and biochemical parameters, blood pressure, and glycemic control?

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20080701

Title: [A new method for safety monitoring of natural dietary supplements--quality profile].

Journal: Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080701

Title: In vitro effect of gliclazide on DNA damage and repair in patients with type 2 diabetes mellitus (T2DM).

Journal: Chemico-biological interactions 20080617

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

Journal: The New England journal of medicine 20080612

Title: Enhancement of dissolution rate of gliclazide using solid dispersions with polyethylene glycol 6000.

Journal: AAPS PharmSciTech 20080601

Title: Thiazolidinedione addition reduces the serum retinol-binding protein 4 in type 2 diabetic patients treated with metformin and sulfonylurea.

Journal: Translational research : the journal of laboratory and clinical medicine 20080601

Title: Comprehensive screening of acidic and neutral drugs in equine plasma by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20080502

Title: Rosiglitazone produces a greater reduction in circulating platelet activity compared with gliclazide in patients with type 2 diabetes mellitus--an effect probably mediated by direct platelet PPARgamma activation.

Journal: Atherosclerosis 20080401

Title: Extensions to the visual predictive check to facilitate model performance evaluation.

Journal: Journal of pharmacokinetics and pharmacodynamics 20080401

Title: Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide.

Journal: British journal of pharmacology 20080401

Title: Novel combination treatment of type 2 diabetes DPP-4 inhibition + metformin.

Journal: Vascular health and risk management 20080401

Title: Erythromelalgia in a diabetic patient managed with gabapentin.

Journal: Diabetes research and clinical practice 20080301

Title: The G53D mutation in Kir6.2 (KCNJ11) is associated with neonatal diabetes and motor dysfunction in adulthood that is improved with sulfonylurea therapy.

Journal: The Journal of clinical endocrinology and metabolism 20080301

Title: Omega-(2-Naphthyloxy) amino alkanes as a novel class of anti-hyperglycemic and lipid lowering agents.

Journal: Bioorganic & medicinal chemistry 20080301

Title: 2-year effects of pioglitazone add-on to sulfonylurea or metformin on oral glucose tolerance in patients with type 2 diabetes.

Journal: Diabetes research and clinical practice 20080301

Title: Therapeutic options for elderly diabetic subjects: open label, randomized clinical trial of insulin glargine added to oral antidiabetic drugs versus increased dosage of oral antidiabetic drugs.

Journal: Acta diabetologica 20080301

Title: Hypoglycaemia in Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20080301

Title: Spermicidal activity of sulfonylureas and meglitinide analogues: role of intrasperm Ca2+ elevation.

Journal: The Journal of pharmacy and pharmacology 20080301

Title: Beneficial effects of rosiglitazone on novel cardiovascular risk factors in patients with Type 2 diabetes mellitus.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20080301

Title: Design and development of gliclazide mucoadhesive microcapsules: in vitro and in vivo evaluation.

Journal: AAPS PharmSciTech 20080301

Title: A flexible nonlinear feedback system that captures diverse patterns of adaptation and rebound.

Journal: The AAPS journal 20080301

Title: [Effects of Tangweian granule on 5-HT(2A)R in rat model with diabetic gastroparesis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301

Title: Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics.

Journal: Methods and findings in experimental and clinical pharmacology 20080301

Title: Antiglycation effect of gliclazide on in vitro AGE formation from glucose and methylglyoxal.

Journal: Experimental biology and medicine (Maywood, N.J.) 20080201

Title: Dissection of the ascending thoracic aorta as a complication of percutaneous coronary intervention.

Journal: Vascular health and risk management 20080201

Title: Ameliorating effects of sulfonylurea drugs on insulin resistance in Otsuka long-evans Tokushima Fatty rats.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20080201

Title: Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.).

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080101

Title: Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects.

Journal: Diabetes/metabolism research and reviews 20080101

Title: Comparative studies of ZD0947, a novel ATP-sensitive K(+) channel opener, on guinea pig detrusor and aortic smooth muscles.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080101

Title: Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells.

Journal: Diabetes/metabolism research and reviews 20080101

Title: Comparison of fixed-dose rosiglitazone/metformin combination therapy with sulphonylurea plus metformin in overweight individuals with Type 2 diabetes inadequately controlled on metformin alone.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20080101

Title: Development of extended zero-order release gliclazide tablets by central composite design.

Journal: Drug development and industrial pharmacy 20080101

Title: PPAR Signaling in Placental Development and Function.

Journal: PPAR research 20080101

Title: Effect of the addition of rosiglitazone to metformin or sulfonylureas versus metformin/sulfonylurea combination therapy on ambulatory blood pressure in people with type 2 diabetes: a randomized controlled trial (the RECORD study).

Journal: Cardiovascular diabetology 20080101

Title: Diabetic control and atypical antipsychotics: a case report.

Journal: Journal of medical case reports 20080101

Title: New onset diabetes complicated by haemolysis and rhabdomyolysis: a case report and review of the literature.

Journal: Journal of medical case reports 20080101

Title: A combination of nutriments improves mitochondrial biogenesis and function in skeletal muscle of type 2 diabetic Goto-Kakizaki rats.

Journal: PloS one 20080101

Title: Primary Biliary Cirrhosis with a normal Alkaline Phosphatase: a case report.

Journal: Cases journal 20080101

Title: Clinical drugs that interact with St. John's wort and implication in drug development.

Journal: Current pharmaceutical design 20080101

Title: Evaluation of the cost effectiveness of exenatide versus insulin glargine in patients with sub-optimally controlled type 2 diabetes in the United Kingdom.

Journal: Cardiovascular diabetology 20080101

Title: Cardioprotective effect of aqueous extract of Embelia ribes Burm fruits against isoproterenol-induced myocardial infarction in albino rats.

Journal: Indian journal of experimental biology 20080101

Title: Performing meta-analysis with incomplete statistical information in clinical trials.

Journal: BMC medical research methodology 20080101

Title: [Blood glucose control and cardiovascular disease in patients with type 2 diabetes. Results of ACCORD, ADVANCE and VA-Diabetes trials].

Journal: Revue medicale de Liege 20080101

Title: Probiotic treatment reduces blood glucose levels and increases systemic absorption of gliclazide in diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Influence of the semisynthetic bile acid (MKC) on the ileal permeation of gliclazide in healthy and diabetic rats.

Journal: Pharmacological reports : PR 20080101

Title: The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease.

Journal: BMJ (Clinical research ed.) 20080101

Title: A diabetic patient presenting with stiff hand following fasciectomy for Dupuytren's contracture: A case report.

Journal: Cases journal 20080101

Title: Vascular and renal benefits are additive using intensive blood pressure control and incremental glucose control in type 2 diabetic patients.

Journal: Cardiovascular journal of Africa 20080101

Title: The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Liquid chromatography--mass spectrometry method for the determination of gliclazide in human plasma and application to a pharmacokinetic study of gliclazide sustained release tablets.

Journal: Arzneimittel-Forschung 20080101

Title: Peroxisome proliferator-activated receptors in diabetic nephropathy.

Journal: PPAR research 20080101

Title: Rapid and Simple RPHPLC Method for the Estimation of Metformin in Rat Plasma.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Simultaneous Estimation of Metformin Hydrochloride and Pioglitazone Hydrochloride by RPHPLC Method from Combined Tablet Dosage Form.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Sulphonylureas induced vasorelaxation of mouse arteries.

Journal: European journal of pharmacology 20071222

Title: Prediction of the metabolic interaction of nateglinide with other drugs based on in vitro studies.

Journal: Drug metabolism and pharmacokinetics 20071201

Title: A review of nateglinide in the management of patients with type 2 diabetes.

Journal: Vascular health and risk management 20071201

Title: Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes.

Journal: Journal of biochemistry 20071101

Title: Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination.

Journal: British journal of clinical pharmacology 20071001

Title: The influence of hydro-alcoholic media on hypromellose matrix systems.

Journal: Drug development and industrial pharmacy 20071001

Title: Optimizing combination treatment in the management of type 2 diabetes.

Journal: Vascular health and risk management 20071001

Title: A review of pioglitazone HCL and glimepiride in the treatment of type 2 diabetes.

Journal: Vascular health and risk management 20071001

Title: [Advanced credit: patient enrolling and therapy initiation in the ADVANCE trial].

Journal: Orvosi hetilap 20070930

Title: Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality.

Journal: Diabetes/metabolism research and reviews 20070901

Title: 'Warm-up' phenomenon in diabetic patients with stable angina treated with diet or sulfonylureas.

Journal: Coronary artery disease 20070901

Title: Long-term effects of pioglitazone versus gliclazide on hepatic and humoral coagulation factors in patients with type 2 diabetes.

Journal: Diabetes & vascular disease research 20070901

Title: Effects of glibenclamide, glimepiride, and gliclazide on ischemic preconditioning in rat heart.

Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20070901

Title: Controlling of systemic absorption of gliclazide through incorporation into alginate beads.

Journal: International journal of pharmaceutics 20070816

Title: Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization.

Journal: Free radical biology & medicine 20070801

Title: The effects of pioglitazone on cerebrovascular resistance in patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20070801

Title: Effect of immunosuppressive and other drugs on the cortisol-cortisone shuttle in human kidney and liver.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070801

Title: Effects of early use of pioglitazone in combination with metformin in patients with newly diagnosed type 2 diabetes.

Journal: Current medical research and opinion 20070801

Title: PROactive 07: pioglitazone in the treatment of type 2 diabetes: results of the PROactive study.

Journal: Vascular health and risk management 20070801

Title: Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes.

Journal: Vascular health and risk management 20070801

Title: Association of sulfonylurea receptor 1 genotype with therapeutic response to gliclazide in type 2 diabetes.

Journal: Diabetes research and clinical practice 20070701

Title: Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects.

Journal: British journal of clinical pharmacology 20070701

Title: Gliclazide: pharmacokinetic-pharmacodynamic relationships in rats.

Journal: Biopharmaceutics & drug disposition 20070701

Title: Nateglinide or gliclazide in combination with metformin for treatment of patients with type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone: 1-year trial results.

Journal: Diabetes, obesity & metabolism 20070701

Title: In-vitro and in-vivo correlation for two gliclazide extended-release tablets.

Journal: The Journal of pharmacy and pharmacology 20070701

Title: Effect of telmisartan in experimentally induced diabetetes mellitus in rats.

Journal: International journal of health sciences 20070701

Title: Sepsis and meningitis due to Listeria monocytogenes.

Journal: Yonsei medical journal 20070630

Title: Development of a RP-HPLC method for screening potentially counterfeit anti-diabetic drugs.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

Title: Rosiglitazone RECORD study: glucose control outcomes at 18 months.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20070601

Title: New insights from ADVANCE.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20070601

Title: Pioglitazone and sulfonylureas: effectively treating type 2 diabetes.

Journal: International journal of clinical practice. Supplement 20070601

Title: Nateglinide quantification in rabbit plasma by HPLC: optimization and application to pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20070509

Title: Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina.

Journal: Diabetologia 20070501

Title: Insulinoma causing hypoglycemia in a patient with type 2 diabetes.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20070501

Title: Induction of long-term glycemic control in type 2 diabetic patients using pioglitazone and metformin combination.

Journal: The Journal of the Association of Physicians of India 20070501

Title: Mixture modeling for the detection of subpopulations in a pharmacokinetic/pharmacodynamic analysis.

Journal: Journal of pharmacokinetics and pharmacodynamics 20070401

Title: Rosiglitazone and glimeperide: review of clinical results supporting a fixed dose combination.

Journal: Vascular health and risk management 20070401

Title: Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose.

Journal: Diabetes/metabolism research and reviews 20070301

Title: A bioequivalence study of gliclazide based on quantification by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.

Journal: International journal of clinical pharmacology and therapeutics 20070301

Title: Comparison of the solubility and dissolution rate between gliclazide solid complex and its nanospheres.

Journal: Drug development and industrial pharmacy 20070301

Title: High-performance liquid chromatography-electrospray ionization mass spectrometry determination of mitiglinide in human plasma and its pharmacokinetics.

Journal: Journal of mass spectrometry : JMS 20070201

Title: Simultaneous determination of metformin and glipizide in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Biomedical chromatography : BMC 20070201

Title: Dual aetiologies for hyperinsulinaemic hypoglycaemia in one patient.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20070201

Title: Preparation and in vitro/in vivo evaluation of gliclazide loaded Eudragit nanoparticles as a sustained release carriers.

Journal: Drug development and industrial pharmacy 20070201

Title: Blood pressure normalization in a large population of hypertensive patients treated with perindopril/indapamide combination: results of the OPTIMAX trial.

Journal: Vascular health and risk management 20070201

Title: Effects of sulfonylureas on left ventricular mass in type 2 diabetic patients.

Journal: American journal of physiology. Heart and circulatory physiology 20070101

Title: Beneficial effects of gliclazide modified release compared with glibenclamide on endothelial activation and low-grade inflammation in patients with type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20070101

Title: The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20070101

Title: Pro-oxidant effect of alpha-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test--a randomised controlled trial.

Journal: Cardiovascular diabetology 20070101

Title: Impact of the short-term, intense exercise on postprandial glycemia in type 2 diabetic patients treated with gliclazide.

Journal: Journal of diabetes and its complications 20070101

Title: Further studies on antioxidant potential and protection of pancreatic beta-cells by Embelia ribes in experimental diabetes.

Journal: Experimental diabetes research 20070101

Title: A cluster randomised controlled trial of educational prompts in diabetes care: study protocol.

Journal: Implementation science : IS 20070101

Title: Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions.

Journal: Cardiovascular diabetology 20070101

Title: In vivo and in vitro evaluation of a solid dispersion system of gliclazide:PEG 6000.

Journal: PDA journal of pharmaceutical science and technology 20070101

Title: [Nail susceptibility to fungal infection in patients with type 1 and 2 diabetes under long term poor glycaemia control].

Journal: Przeglad lekarski 20070101

Title: Pioglitazone and metformin fixed-dose combination in type 2 diabetes mellitus: an evidence-based review of its place in therapy.

Journal: Core evidence 20070101

Title: A case of mistaken identity.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20061201

Title: Effect of Kaiyu Qingwei Jianji on the morphometry and residual strain distribution of small intestine in experimental diabetic rats.

Journal: World journal of gastroenterology 20061128

Title: Association of gliclazide and left ventricular mass in type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20061101

Title: Contribution of solid-state properties to the aqueous solubility of drugs.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061101

Title: Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes.

Journal: British journal of pharmacology 20061101

Title: Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression.

Journal: Metabolism: clinical and experimental 20061101

Title: Effects of isopropyl palmitate on the skin permeation of drugs.

Journal: Biological & pharmaceutical bulletin 20061101

Title: Application of monolithic column in quantification of gliclazide in human plasma by liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20061011

Title: Hair to document exposure to glibenclamide.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061002

Title: Simultaneous estimation of six anti-diabetic drugs--glibenclamide, gliclazide, glipizide, pioglitazone, repaglinide and rosiglitazone: development of a novel HPLC method for use in the analysis of pharmaceutical formulations and its application to human plasma assay.

Journal: Biomedical chromatography : BMC 20061001

Title: Influence of nicorandil on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits.

Journal: Molecular and cellular biochemistry 20061001

Title: Effect of gliclazide modified release on adiponectin, interleukin-6, and tumor necrosis factor-alpha plasma levels in individuals with type 2 diabetes mellitus.

Journal: Current medical research and opinion 20061001

Title: Drug-induced hypoglycaemia--new insight into an old problem.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20061001

Title: Effect of gliclazide on DNA damage in human peripheral blood lymphocytes and insulinoma mouse cells.

Journal: Chemico-biological interactions 20060925

Title: Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide.

Journal: Pharmaceutical research 20060901

Title: Gliclazide treatment lowers serum ICAM-1 levels in poorly controlled type 2 diabetic patients.

Journal: Diabetes & metabolism 20060901

Title: Clinical observation on effect of Kaixin capsule in treating 40 patients with diabetic myocardial ischemia.

Journal: Chinese journal of integrative medicine 20060901

Title: Monogenic diabetes in children and young adults: Challenges for researcher, clinician and patient.

Journal: Reviews in endocrine & metabolic disorders 20060901

Title: ADVANCE: breaking new ground in type 2 diabetes.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060801

Title: Antidiabetic activity of an ethanol extract obtained from the stem bark of Psidium guajava (Myrtaceae).

Journal: Die Pharmazie 20060801

Title: [Rhabdomyolysis induced by fenofibrate monotherapy].

Journal: La Revue de medecine interne 20060701

Title: Is it time to re-assess the role of gliclazide? Targeting insulin resistance in type 2 diabetes patients suboptimally controlled with insulin.

Journal: Postgraduate medical journal 20060701

Title: Comparison of nateglinide and gliclazide in combination with metformin, for treatment of patients with Type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20060701

Title: A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus.

Journal: Journal of pharmacokinetics and pharmacodynamics 20060601

Title: Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation.

Journal: Metabolism: clinical and experimental 20060601

Title: Gliclazide inhibits differentiation-associated biologic events in human monocyte-derived macrophages.

Journal: Metabolism: clinical and experimental 20060601

Title: The development of non-insulin-dependent diabetes after total body irradiation and bone marrow transplantation in adolescence: a case report and literature review.

Journal: Pediatric diabetes 20060601

Title: Novel substituted naphthalen-1-yl-methanone derivatives as anti-hyperglycemic agents.

Journal: Bioorganic & medicinal chemistry letters 20060515

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Effects of gliclazide beyond metabolic control.

Journal: Metabolism: clinical and experimental 20060501

Title: Overcoming the hurdles to achieving glycemic control.

Journal: Metabolism: clinical and experimental 20060501

Title: Managing hypertension in high-risk patients: lessons and promises from the STRATHE and ADVANCE trials.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060501

Title: Lymphocyte ecto-5'-nucleotidase in obese type 2 diabetic patients treated with gliclazide.

Journal: Diabetes & metabolism 20060401

Title: Double-blind, randomized, multicentre study of the efficacy and safety of gliclazide-modified release in the treatment of Chinese type 2 diabetic patients.

Journal: Diabetes, obesity & metabolism 20060301

Title: Comparison of glycaemic control over 1 year with pioglitazone or gliclazide in patients with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20060301

Title: Anti-diabetic and hypolipidemic effects of aqueous-extract from the flower of Inula japonica in alloxan-induced diabetic mice.

Journal: Biological & pharmaceutical bulletin 20060301

Title: [Prevalence and consumption of medication in diabetes mellitus in Madrid (1996-2002)].

Journal: Revista clinica espanola 20060301

Title: [Review of the interference between the most commonly prescribed drugs and clinical analyses at the Primary Health Care Centre of L'Hospitalet de Llobregat].

Journal: Atencion primaria 20060227

Title: Microalbuminuria as a marker of cardiovascular risk in patients with type 2 diabetes.

Journal: International journal of cardiology 20060215

Title: Influence of selenium (antioxidant) on gliclazide induced hypoglycaemia/anti hyperglycaemia in normal/alloxan-induced diabetic rats.

Journal: Molecular and cellular biochemistry 20060201

Title: Effect of vitamin E and C supplementation combined with oral antidiabetic therapy on the endothelial dysfunction in the neonatally streptozotocin injected diabetic rat.

Journal: Diabetes/metabolism research and reviews 20060101

Title: Effects of sulfonylureas on mitochondrial ATP-sensitive K+ channels in cardiac myocytes: implications for sulfonylurea controversy.

Journal: Diabetes/metabolism research and reviews 20060101

Title: Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study.

Journal: Journal of inflammation (London, England) 20060101

Title: Comparison of the antioxidant and vascular effects of gliclazide and glibenclamide in Type 2 diabetic patients: a randomized crossover study.

Journal: Journal of diabetes and its complications 20060101

Title: Three-year mortality in diabetic patients treated with different combinations of insulin secretagogues and metformin.

Journal: Diabetes/metabolism research and reviews 20060101

Title: Development and validation of a new high-performance liquid chromatography method for the determination of gliclazide and repaglinide in pharmaceutical formulations.

Journal: Journal of AOAC International 20060101

Title: A fixed-dose combination of pioglitazone and metformin: A promising alternative in metabolic control.

Journal: Current medical research and opinion 20060101

Title: Single and multiple dose bioequivalence evaluation of two brands of gliclazide modified release tablets in healthy Chinese male volunteers.

Journal: Arzneimittel-Forschung 20060101

Title: Severe combined hyperlipidaemia and retinal lipid infiltration in a patient with Type 2 diabetes mellitus.

Journal: Lipids in health and disease 20060101

Title: The effectiveness of various doses of octreotide for sulfonylurea-induced hypoglycemia after overdose.

Journal: Advances in therapy 20060101

Title: Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS).

Journal: PPAR research 20060101

Title: Secondary sulfonylurea failure: comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.

Journal: Diabetes research and clinical practice 20051201

Title: Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms.

Journal: The Journal of physiology 20051201

Title: Long-term effects on lipids and lipoproteins of pioglitazone versus gliclazide addition to metformin and pioglitazone versus metformin addition to sulphonylurea in the treatment of type 2 diabetes.

Journal: Diabetologia 20051201

Title: Cardiovascular disease in diabetic nephropathy patients: cell adhesion molecules as potential markers?

Journal: Vascular health and risk management 20051201

Title: The DIACOM study (effect of DosIng frequency of oral Antidiabetic agents on the COMpliance and biochemical control of type 2 diabetes).

Journal: Diabetes, obesity & metabolism 20051101

Title: Simultaneous determination of metformin and gliclazide in human plasma by liquid chromatography-tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy volunteers.

Journal: Journal of mass spectrometry : JMS 20051101

Title: [The multi-level Meta analysis model combining individual level data with aggregative level data].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101

Title: Safety and tolerability of pioglitazone, metformin, and gliclazide in the treatment of type 2 diabetes.

Journal: Diabetes research and clinical practice 20051001

Title: Synthesis and characterization of gliclazide complexes of magnesium, calcium, chromium, manganese, iron, nickel, copper, zinc and cadmium salts.

Journal: Pakistan journal of pharmaceutical sciences 20051001

Title: [A multicenter clinic study of slow-release-gliclazide in type 2 diabetes mellitus].

Journal: Zhonghua yi xue za zhi 20050928

Title: High-performance liquid chromatography with electrochemical detection for analysis of gliclazide in plasma.

Journal: Journal of chromatography. A 20050923

Title: Determination of aminoheterocycle and azabicycle in gliclazide bulk by capillary zone electrophoresis with amperometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: Identification and quantification of 8 sulfonylureas with clinical toxicology interest by liquid chromatography-ion-trap tandem mass spectrometry and library searching.

Journal: Clinical chemistry 20050901

Title: Management of diabetes during Ramadan.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050901

Title: Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes.

Journal: Current eye research 20050901

Title: [Recent oral antidiabetic therapy].

Journal: Revue medicale de Bruxelles 20050901

Title: Changes in liver tests during 1-year treatment of patients with Type 2 diabetes with pioglitazone, metformin or gliclazide.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050801

Title: Sulphonylureas in the management of type 2 diabetes during the fasting month of Ramadan.

Journal: Journal of the Indian Medical Association 20050801

Title: Confusing tablets.

Journal: Lancet (London, England) 20050701

Title: Long-term efficacy and tolerability of add-on pioglitazone therapy to failing monotherapy compared with addition of gliclazide or metformin in patients with type 2 diabetes.

Journal: Diabetologia 20050601

Title: Pharmaceutical availability of gliclazide from selected matrix formulation tablets.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20050601

Title: Efficacy of glimepiride in Japanese type 2 diabetic subjects.

Journal: Diabetes research and clinical practice 20050601

Title: The effect of gliclazide and glibenclamide on preconditioning of the human myocardium.

Journal: European journal of pharmacology 20050516

Title: Late steroid withdrawal for renal transplant recipients on tacrolimus and MMF is safe.

Journal: Transplantation proceedings 20050501

Title: [Controversial therapeutic strategies in the treatment of type 2 diabetes mellitus].

Journal: MMW Fortschritte der Medizin 20050428

Title: A long-term comparison of pioglitazone and gliclazide in patients with Type 2 diabetes mellitus: a randomized, double-blind, parallel-group comparison trial.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050401

Title: Evaluation of drug therapy and risk factors in diabetic hypertensives: a study of the quality of care provided in diabetic clinics in Bahrain.

Journal: Journal of evaluation in clinical practice 20050401

Title: The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide or glimperide in plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325

Title: [54-year-old patient with type 2 diabetes mellitus and increased blood pressure values].

Journal: Praxis 20050316

Title: Comparison of pioglitazone and gliclazide in sustaining glycemic control over 2 years in patients with type 2 diabetes.

Journal: Diabetes care 20050301

Title: Pioglitazone elicits long-term improvements in insulin sensitivity in patients with type 2 diabetes: comparisons with gliclazide-based regimens.

Journal: Diabetologia 20050301

Title: Effect of ethanolic extract of Zingiber officinale on dyslipidaemia in diabetic rats.

Journal: Journal of ethnopharmacology 20050227

Title: Comparison of effect of pioglitazone with metformin or sulfonylurea (monotherapy and combination therapy) on postload glycemia and composite insulin sensitivity index during an oral glucose tolerance test in patients with type 2 diabetes.

Journal: Diabetes care 20050201

Title: The effect of short-term glycemic regulation with gliclazide and metformin on postprandial lipemia.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050201

Title: Long-term therapy with addition of pioglitazone to metformin compared with the addition of gliclazide to metformin in patients with type 2 diabetes: a randomized, comparative study.

Journal: Diabetes/metabolism research and reviews 20050101

Title: Effect of repaglinide and gliclazide on postprandial control of endogenous glucose production.

Journal: Metabolism: clinical and experimental 20050101

Title: Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients.

Journal: Clinical physiology and functional imaging 20050101

Title: Gliclazide modified release.

Journal: Drugs 20050101

Title: Bench-to-bedside review: Antidotal treatment of sulfonylurea-induced hypoglycaemia with octreotide.

Journal: Critical care (London, England) 20050101

Title: Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model.

Journal: Endocrine research 20050101

Title: Exubera(®) (inhaled insulin): an evidence-based review of its effectiveness in the management of diabetes.

Journal: Core evidence 20050101

Title: Rational pharmacotherapy in the diabetic hypertension: analysis-prescribing patterns in a general hospital in Taiwan.

Journal: Journal of clinical pharmacy and therapeutics 20041201

Title: Effect of aqueous extract of Cyamopsis tetragonoloba Linn. beans on blood glucose level in normal and alloxan-induced diabetic rats.

Journal: Indian journal of experimental biology 20041201

Title: Detection of anti-diabetics in equine plasma and urine by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041105

Title: Gliclazide modified release: results of a 2-year study in patients with type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20041101

Title: Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes.

Journal: Diabetologia 20041101

Title: Effects of pioglitazone on the components of diabetic dyslipidaemia: results of double-blind, multicentre, randomised studies.

Journal: International journal of clinical practice 20041001

Title: [Therapy objectives and daily practice--to which extent are blood sugar target values accessible in daily practice?].

Journal: Praxis 20040929

Title: Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes.

Journal: Biochemical pharmacology 20040901

Title: Cardiovascular effects of treatment of type 2 diabetes with pioglitazone, metformin and gliclazide.

Journal: International journal of clinical practice 20040901

Title: Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.

Journal: Pharmacological research 20040801

Title: GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients.

Journal: European journal of clinical investigation 20040801

Title: Efficacy and safety of once daily gliclazide (20 mg/day) compared with nateglinide.

Journal: Endocrine journal 20040801

Title: [2-year data of large clinical comparative studies. Type 2 diabetes: lasting metabolic control with pioglitazone].

Journal: MMW Fortschritte der Medizin 20040722

Title: Severe and resistant hypoglycemia associated with concomitant gatifloxacin and glyburide therapy.

Journal: Pharmacotherapy 20040701

Title: [The efficacy and safety of 30 mg slow-released-gliclazide in type 2 diabetes mellitus].

Journal: Zhonghua nei ke za zhi 20040701

Title: Quantification of gliclazide by semi-micro high-performance liquid chromatography: application to a bioequivalence study of two formulations in healthy subjects.

Journal: Journal of pharmaceutical and biomedical analysis 20040629

Title: Advanced glycation end-products increase monocyte adhesion to retinal endothelial cells through vascular endothelial growth factor-induced ICAM-1 expression: inhibitory effect of antioxidants.

Journal: Journal of leukocyte biology 20040601

Title: Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes.

Journal: Diabetes research and clinical practice 20040601

Title: Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040601

Title: The effect of deinsuring chlorpropamide on the prescribing of oral antihyperglycemics for Nova Scotia Seniors' Pharmacare beneficiaries.

Journal: Pharmacotherapy 20040601

Title: Comparison of uptitration of gliclazide with the addition of rosiglitazone to gliclazide in patients with type 2 diabetes inadequately controlled on half-maximal doses of a sulphonylurea.

Journal: Acta diabetologica 20040601

Title: Effects of thioacetamide on pancreatic islet B-cell function.

Journal: Endocrine 20040601

Title: Octreotide treatment for sulfonylurea-induced hypoglycaemia.

Journal: The Medical journal of Australia 20040517

Title: The effects of diet, sulfonylurea, and Repaglinide therapy on clinical and metabolic parameters in type 2 diabetic patients during Ramadan.

Journal: Endocrine research 20040501

Title: [Effect of sanhuang jiangtang recipe on renin-angiotensin system in local myocardium in diabetic rats].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401

Title: Gliclazide at a lower concentration than therapeutic dose increases the sensitivity of insulin secretion to glucose in perfused rat pancreas.

Journal: Diabetes & metabolism 20040401

Title: [Long-term HbA1c stable. Insulin sensitizer keeps diabetes in check].

Journal: MMW Fortschritte der Medizin 20040325

Title: Inhibition of ATP-sensitive K+ channels by taurine through a benzamido-binding site on sulfonylurea receptor 1.

Journal: Biochemical pharmacology 20040315

Title: Erosion induced controllable release of gliclazide encapsulated inside degradable polymeric particles.

Journal: Macromolecular bioscience 20040315

Title: Signalling pathways involved in retinal endothelial cell proliferation induced by advanced glycation end products: inhibitory effect of gliclazide.

Journal: Diabetes, obesity & metabolism 20040301

Title: NMDA receptor subunits 2A and 2B decrease and lipid peroxidation increase in the hippocampus of streptozotocin-diabetic rats: effects of insulin and gliclazide treatments.

Journal: The International journal of neuroscience 20040301

Title: Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet.

Journal: Kidney international 20040301

Title: Effect of antidiabetic medications on microalbuminuria in patients with type 2 diabetes.

Journal: Metabolism: clinical and experimental 20040301

Title: Myocardial protection from either ischaemic preconditioning or nicorandil is not blocked by gliclazide.

Journal: Cardiovascular drugs and therapy 20040301

Title: [Compliance and optimisation of oral antidiabetic therapy. A longitudinal study].

Journal: Presse medicale (Paris, France : 1983) 20040214

Title: Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle.

Journal: Endocrinology 20040201

Title: Long-term glycaemic control with pioglitazone in patients with type 2 diabetes.

Journal: International journal of clinical practice 20040201

Title: Favorable effects of pioglitazone and metformin compared with gliclazide on lipoprotein subfractions in overweight patients with early type 2 diabetes.

Journal: Diabetes care 20040101

Title: Protective actions of gliclazide on high insulin-enhanced neutrophil-endothelial cell interactions through inhibition of mitogen activated protein kinase and protein kinase C pathways.

Journal: Microvascular research 20040101

Title: Spectrophotometric determination of gliclazide in pharmaceuticals and biological fluids through ternary complex formation with eosin and palladium (II).

Journal: Farmaco (Societa chimica italiana : 1989) 20040101

Title: The antidiabetic agent, gliclazide, reduces high insulin-enhanced neutrophil-transendothelial migration through direct effects on the endothelium.

Journal: Diabetes/metabolism research and reviews 20040101

Title: The role of sulphonylureas in the management of type 2 diabetes mellitus.

Journal: Drugs 20040101

Title: Chinese herbal medicines for type 2 diabetes mellitus.

Journal: The Cochrane database of systematic reviews 20040101

Title: NIDDM: new once-daily intervention for type 2 diabetes mellitus: Diaprel MR.

Journal: Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101

Title: [A prospective randomized study of sulphonylureas therapeutic interchange in patients with type 2 diabetes mellitus].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101

Title: Pharmacokinetic differences of some generic tablet gliclazide 80 mg on Pakistani population.

Journal: Pakistan journal of pharmaceutical sciences 20040101

Title: Comparison of repaglinide vs. gliclazide in combination with bedtime NPH insulin in patients with Type 2 diabetes inadequately controlled with oral hypoglycaemic agents.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20031101

Title: Effects of rosiglitazone maleate when added to a sulfonylurea regimen in patients with type 2 diabetes mellitus and mild to moderate renal impairment: a post hoc analysis.

Journal: Clinical therapeutics 20031101

Title: Genetic cause of hyperglycaemia and response to treatment in diabetes.

Journal: Lancet (London, England) 20031018

Title: Effect of rifampin on the pharmacokinetics and pharmacodynamics of gliclazide.

Journal: Clinical pharmacology and therapeutics 20031001

Title: Monotherapy of type 2 diabetes with once-daily gliclazide modified release in primary care.

Journal: Diabetes research and clinical practice 20031001

Title: Risk of hypoglycaemia with oral antidiabetic agents in patients with Type 2 diabetes.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20031001

Title: [Medication of the month. Gliclazide modified release (Uni Diamicron)].

Journal: Revue medicale de Liege 20031001

Title: Reflex epilepsy and non-ketotic hyperglycemia.

Journal: Epileptic disorders : international epilepsy journal with videotape 20030901

Title: Benefits of gliclazide in the atherosclerotic process: decrease in monocyte adhesion to endothelial cells.

Journal: Metabolism: clinical and experimental 20030801

Title: Gliclazide modified release: A critical review of pharmacodynamic, metabolic, and vasoprotective effects.

Journal: Metabolism: clinical and experimental 20030801

Title: Bioequivalence study of generic gliclazide and Diamicron formulations in healthy Thai male volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20030701

Title: The application of the convective diffusion model and the film equilibrium model to surfactant-facilitated dissolution of gliclazide.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030701

Title: Pharmacokinetic and pharmacodynamic characterization of gliclazide in healthy volunteers.

Journal: Archives of pharmacal research 20030701

Title: Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels.

Journal: British journal of pharmacology 20030601

Title: Comparison of the micro- and macro-vascular effects of glimepiride and gliclazide in metformin-treated patients with Type 2 diabetes: a double-blind, crossover study.

Journal: British journal of clinical pharmacology 20030601

Title: Diabetes and vascular disease: a new international trial.

Journal: Asian cardiovascular & thoracic annals 20030601

Title: Sulfonylureas and cardiovascular effects: from experimental data to clinical use. Available data in humans and clinical applications.

Journal: Diabetes & metabolism 20030601

Title: Upregulation of cyclooxygenase-2 is accompanied by increased expression of nuclear factor-kappa B and I kappa B kinase-alpha in human colorectal cancer epithelial cells.

Journal: British journal of cancer 20030519

Title: Urinary PC-1 and N-acetyl-beta-D-glucosaminidase activity in patients with type 2 diabetes treated with metformin, gliclazide or glibenclamide.

Journal: Annals of clinical biochemistry 20030501

Title: Study of the solubilization of gliclazide by aqueous micellar solutions.

Journal: Journal of pharmaceutical sciences 20030401

Title: Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide.

Journal: Biochemical and biophysical research communications 20030328

Title: A simple and sensitive HPLC method for determination of gliclazide in human serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

Title: Gliclazide as novel carrier in construction of PVC-based La(III)-selective membrane sensor.

Journal: Talanta 20030301

Title: Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation.

Journal: British journal of clinical pharmacology 20030201

Title: Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers.

Journal: Fundamental & clinical pharmacology 20030201

Title: Diabetes mellitus and weight control: differences of respiratory quotient in type 2 diabetic obese subjects receiving sulfonylureas and non-diabetic obese controls.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20030201

Title: Severe relapsing sulphonylurea-induced hypoglycaemia: a diagnostic and therapeutic challenge.

Journal: Postgraduate medical journal 20030201

Title: The mechanisms of inhibitory actions of gliclazide on neutrophils-endothelial cells adhesion and surface expression of endothelial adhesion molecules mediated by a high glucose concentration.

Journal: Journal of diabetes and its complications 20030101

Title: Effects of inhibition of ATP-sensitive potassium channels on metabolic vasodilation in the human forearm.

Journal: Clinical science (London, England : 1979) 20030101

Title: Effects of sulfonylureas on K(ATP) channel-dependent vasodilation.

Journal: Journal of diabetes and its complications 20030101

Title: Differential selectivity of insulin secretagogues: mechanisms, clinical implications, and drug interactions.

Journal: Journal of diabetes and its complications 20030101

Title: Monocyte adhesion in diabetic angiopathy: effects of free-radical scavenging.

Journal: Journal of diabetes and its complications 20030101

Title: Diabetic endothelial dysfunction: effect of free radical scavenging in Type 2 diabetic patients.

Journal: Journal of diabetes and its complications 20030101

Title: Monocyte matrix metalloproteinase production in Type 2 diabetes and controls--a cross sectional study.

Journal: Cardiovascular diabetology 20030101

Title: Spectrofluorimetric and spectrophotometric determination of gliclazide in pharmaceuticals by derivatization with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole.

Journal: Journal of AOAC International 20030101

Title: Addition of rosiglitazone to existing sulfonylurea treatment in chinese patients with type 2 diabetes and exposure to hepatitis B or C.

Journal: Diabetes technology & therapeutics 20030101

Title: [A 50-year history of new drugs in Japan-the development and progress of anti-diabetic drugs and the epidemiological aspects of diabetes mellitus].

Journal: Yakushigaku zasshi 20030101

Title: In vitro availability of gliclazide in presence of antacids.

Journal: Pakistan journal of pharmaceutical sciences 20030101

Title: Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells.

Journal: The Journal of experimental biology 20021201

Title: Sulfonylurea stimulation of insulin secretion.

Journal: Diabetes 20021201

Title: Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.

Journal: Diabetes 20021201

Title: Gliclazide directly inhibits arginine-induced glucagon release.

Journal: Diabetes 20021201

Title: Combination therapy of alpha-glucosidase inhibitor and a sulfonylurea compound prolongs the duration of good glycemic control.

Journal: Metabolism: clinical and experimental 20021201

Title: Hypoglycaemic activity of Alpinia galanga rhizome and its extracts in rabbits.

Journal: Fitoterapia 20021201

Title: [Molecular mechanisms of insulin secretion].

Journal: Diabetes & metabolism 20021201

Title: High-frequency insulin pulsatility and type 2 diabetes: from physiology and pathophysiology to clinical pharmacology.

Journal: Diabetes & metabolism 20021201

Title: Eudragit NE30D based metformin/gliclazide extended release tablets: formulation, characterisation and in vitro release studies.

Journal: Chemical & pharmaceutical bulletin 20021101

Title: Effect of gliclazide on islet transplants.

Journal: Transplantation proceedings 20021101

Title: Remodelling of zero-stress state of small intestine in streptozotocin-induced diabetic rats. Effect of gliclazide.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20021001

Title: Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20020901

Title: Gateways to Clinical Trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020901

Title: A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.

Journal: Analytical biochemistry 20020815

Title: Bioequivalence evaluation of two brands of gliclazide 80 mg tablets (Glyzide & Diamicron)--in healthy human volunteers.

Journal: Biopharmaceutics & drug disposition 20020701

Title: Antiaggregatory activity of hypoglycaemic sulphonylureas.

Journal: Diabetologia 20020701

Title: Oral hypoglycaemic agent failure.

Journal: Journal of the Indian Medical Association 20020701

Title: Method development for analysis of gliclazide in human plasma by using high-performance liquid chromatography.

Journal: Pakistan journal of pharmaceutical sciences 20020701

Title: Acute gliclazide administration enhances glucose and ketone body utilization in the perfused hind limb of normal and streptozotocin-diabetic rats.

Journal: Life sciences 20020628

Title: Screening, library-assisted identification and validated quantification of oral antidiabetics of the sulfonylurea-type in plasma by atmospheric pressure chemical ionization liquid chromatography-mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020615

Title: Effect of pioglitazone on blood proinsulin levels in patients with type 2 diabetes mellitus.

Journal: Endocrine journal 20020601

Title: Complete bioavailability and lack of food-effect on pharmacokinetics of gliclazide 30 mg modified release in healthy volunteers.

Journal: Biopharmaceutics & drug disposition 20020501

Title: Gliclazide-induced acute hepatitis with hypersensitivity features.

Journal: Digestive diseases and sciences 20020501

Title: Effective and selective prevention of retinal leukostasis in streptozotocin-induced diabetic rats using gliclazide.

Journal: Diabetologia 20020501

Title: Studies on solubility and hypoglycemic activity of gliclazide beta-cyclodextrin-hydroxypropylmethylcellulose complexes.

Journal: Die Pharmazie 20020301

Title: Adenosine triphosphate-sensitive potassium (K(ATP)) channel activity is coupled with insulin resistance in obesity and type 2 diabetes mellitus.

Journal: Internal medicine (Tokyo, Japan) 20020201

Title: Family physicians' and general practitioners' approaches to drug management of diabetic hypertension in primary care.

Journal: Journal of evaluation in clinical practice 20020201

Title: Does gliclazide stimulate first-phase, second-phase, or both phases of insulin release?

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020201

Title: New trends in the development of oral antidiabetic drugs.

Journal: Current medicinal chemistry 20020101

Title: Participation of high glucose concentrations in neutrophil adhesion and surface expression of adhesion molecules on cultured human endothelial cells: effect of antidiabetic medicines.

Journal: Journal of diabetes and its complications 20020101

Title: Hepatotoxicity of commonly used drugs: nonsteroidal anti-inflammatory drugs, antihypertensives, antidiabetic agents, anticonvulsants, lipid-lowering agents, psychotropic drugs.

Journal: Seminars in liver disease 20020101

Title: Gliclazide modified release.

Journal: Drugs 20020101

Title: Advanced glycation end products increase, through a protein kinase C-dependent pathway, vascular endothelial growth factor expression in retinal endothelial cells. Inhibitory effect of gliclazide.

Journal: Journal of diabetes and its complications 20020101

Title: Trends in oral antihyperglycemic and insulin use in the Nova Scotia senior population (1993-1999).

Journal: The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20020101

Title: Effect of ethanolic extract of Embelia ribes on dyslipidemia in diabetic rats.

Journal: International journal of experimental diabetes research 20020101

Title: Regulation of glucose transporter 1 expression by gliclazide in rat L6 myoblasts.

Journal: Diabetes, nutrition & metabolism 20011201

Title: Increments in insulin sensitivity during intensive treatment are closely correlated with decrements in glucocorticoid receptor mRNA in skeletal muscle from patients with Type II diabetes.

Journal: Clinical science (London, England : 1979) 20011101

Title: Prescribing patterns and therapeutic implications for diabetic hypertension in Bahrain.

Journal: The Annals of pharmacotherapy 20011101

Title: Structural basis for the interference between nicorandil and sulfonylurea action.

Journal: Diabetes 20011001

Title: Possible interaction between gliclazide, fluconazole and sulfamethoxazole resulting in severe hypoglycaemia.

Journal: British journal of clinical pharmacology 20011001

Title: Liver failure after long-term nucleoside antiretroviral therapy.

Journal: Lancet (London, England) 20010901

Title: Study rationale and design of ADVANCE: action in diabetes and vascular disease--preterax and diamicron MR controlled evaluation.

Journal: Diabetologia 20010901

Title: Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes.

Journal: Diabetes 20010801

Title: Gliclazide produces high-affinity block of KATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells.

Journal: Diabetologia 20010801

Title: Glibenclamide vs gliclazide in reducing oxidative stress in patients of noninsulin dependent diabetes mellitus--a double blind randomized study.

Journal: The Journal of the Association of Physicians of India 20010801

Title: Gliclazide decreases vascular smooth muscle cell dysfunction induced by cell-mediated oxidized low-density lipoprotein.

Journal: Metabolism: clinical and experimental 20010601

Title: Gliclazide mainly affects insulin secretion in second phase of type 2 diabetes mellitus.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601

Title: ATP-Sensitive potassium channels modulate glucose transport in cultured human skeletal muscle cells.

Journal: Endocrine journal 20010601

Title: [Effects of gliclazide on blood rheology of diabetes Wistar rat].

Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010601

Title: Characteristics of pancreatic beta-cell secretion in Type 2 diabetic patients treated with gliclazide and glibenclamide.

Journal: Diabetes research and clinical practice 20010501

Title: ION-pair liquid chromatography technique for the estimation of metformin in its multicomponent dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis 20010401

Title: Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.

Journal: Diabetes care 20010401

Title: 24-hour glycemic profile in type 2 diabetic patients treated with gliclazide modified release once daily.

Journal: Diabetes & metabolism 20010401

Title: Effect of KAD-1229, a nonsulfonylurea hypoglycemic agent, on plasma glucose and insulin in streptozotocin-induced diabetic dogs.

Journal: Pharmacology 20010201

Title: Gliclazide and bedtime insulin are more efficient than insulin alone for type 2 diabetic patients with sulfonylurea secondary failure.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010101

Title: Comparison of acarbose and gliclazide as first-line agents in patients with type 2 diabetes.

Journal: Current medical research and opinion 20010101

Title: Comparison of the effects of three sulfonylureas on in vivo insulin action.

Journal: Arzneimittel-Forschung 20010101

Title: [Free radical scavenging activity of sulfonylureas: a clinical assessment of the effectiveness of gliclazide].

Journal: Terapevticheskii arkhiv 20010101

Title: Repaglinide: a review of its therapeutic use in type 2 diabetes mellitus.

Journal: Drugs 20010101

Title: Gliclazide-induced hepatitis, hemiplegia and dysphasia in a suicide attempt.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20010101

Title: [Toxicological analysis in the dawn of the third millenium].

Journal: Annales de biologie clinique 20010101

Title: [Recurrent toxic severe hypoglycemias].

Journal: Annales de biologie clinique 20010101

Title: Determination of gliclazide in pharmaceutical preparations by capillary gas chromatography with cool on-column injection and elimination of the matrix effect.

Journal: Journal of AOAC International 20010101

Title: [Antioxidant and anti-AGE therapeutics: evaluation and perspectives].

Journal: Journal de la Societe de biologie 20010101

Title: Gliclazide-induced acute hepatitis.

Journal: European journal of gastroenterology & hepatology 20000101

Title: Cardiovascular effects of conventional sulfonylureas and glimepiride.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 19960901

Title: Possible gliclazide-induced water retention with azotemia.

Journal: Internal medicine (Tokyo, Japan) 19940301

Title: Shimoyama, T., et al., Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation. Metabolism, 2006. 55(6): p. 722-30.

Title: Lawrence, C.L., et al., Gliclazide produces high-affinity block of KATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells. Diabetologia, 2001. 44(8): p. 1019-25.

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Tags:21187-98-4 Molecular Formula|21187-98-4 MDL|21187-98-4 SMILES|21187-98-4 1-[(4-methylbenzene)sulfonyl]-3-{octahydrocyclopenta[c]pyrrol-2-yl}urea