Home Amines 211914-51-1
211914-51-1,MFCD09837830
Catalog No.:AA00I3Z4

211914-51-1 | 3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid

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2mg
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5mg
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$8.00   $6.00
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10mg
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$13.00   $9.00
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50mg
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$28.00   $20.00
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100mg
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$47.00   $33.00
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250mg
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$68.00   $48.00
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1g
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5g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I3Z4
Chemical Name:
3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid
CAS Number:
211914-51-1
Molecular Formula:
C25H25N7O3
Molecular Weight:
471.5111
MDL Number:
MFCD09837830
SMILES:
OC(=O)CCN(C(=O)c1ccc2c(c1)nc(n2C)CNc1ccc(cc1)C(=N)N)c1ccccn1
Properties
Computed Properties
 
Complexity:
757  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
9  
XLogP3:
1.7  

Downstream Synthesis Route

[1]Hauel,NorbertH.;Nar,Herbert;Priepke,Henning;Ries,Uwe;Stassen,Jean-Marie;Wienen,Wolfgang[JournalofMedicinalChemistry,2002,vol.45,#9,p.1757-1766]

[2]CurrentPatentAssignee:C.H.BoehringerSohnAG&Co.KG-US6087380,2000,A

[1]Hauel,NorbertH.;Nar,Herbert;Priepke,Henning;Ries,Uwe;Stassen,Jean-Marie;Wienen,Wolfgang[JournalofMedicinalChemistry,2002,vol.45,#9,p.1757-1766]

[2]CurrentPatentAssignee:HAISCOPHARMACEUTICALGROUPCO.,LTD.-CN103524559,2016,B

41263-74-5   
dabigatran 

[1]JournalofMedicinalChemistry,2002,vol.45,p.1757-1766

[2]Patent:CN103524559,2016,B

[1]Hauel,NorbertH.;Nar,Herbert;Priepke,Henning;Ries,Uwe;Stassen,Jean-Marie;Wienen,Wolfgang[JournalofMedicinalChemistry,2002,vol.45,#9,p.1757-1766]

[2]CurrentPatentAssignee:HAISCOPHARMACEUTICALGROUPCO.,LTD.-CN103524559,2016,B

429659-01-8   
dabigatran 

[1]Hauel,NorbertH.;Nar,Herbert;Priepke,Henning;Ries,Uwe;Stassen,Jean-Marie;Wienen,Wolfgang[JournalofMedicinalChemistry,2002,vol.45,#9,p.1757-1766]

[2]CurrentPatentAssignee:HAISCOPHARMACEUTICALGROUPCO.,LTD.-CN103524559,2016,B

Literature

Title: Overview of the new oral anticoagulants: opportunities and challenges.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20150501

Title: Thrombin inhibition with dabigatran protects against high-fat diet-induced fatty liver disease in mice.

Journal: The Journal of pharmacology and experimental therapeutics 20141101

Title: Low molecular weight dual inhibitors of factor Xa and fibrinogen binding to GPIIb/IIIa with highly overlapped pharmacophores.

Journal: European journal of medicinal chemistry 20130601

Title: A specific antidote for dabigatran: functional and structural characterization.

Journal: Blood 20130502

Title: The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters.

Journal: Thrombosis research 20121101

Title: Use of direct thrombin inhibitor for treatment of cerebral venous thrombosis.

Journal: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20121101

Title: Intravenous thrombolysis in a stroke patient taking dabigatran.

Journal: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20121101

Title: Dabigatran and left atrial appendage thrombus.

Journal: Journal of thrombosis and thrombolysis 20121101

Title: Acute ischemic stroke treated with intravenous tissue plasminogen activator in a patient taking dabigatran with radiographic evidence of recanalization.

Journal: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20121101

Title: The effects of direct thrombin inhibition with dabigatran on plaque formation and endothelial function in apolipoprotein E-deficient mice.

Journal: The Journal of pharmacology and experimental therapeutics 20121101

Title: Dabigatran is effective with a favourable safety profile in normal and overweight patients undergoing major orthopaedic surgery: a pooled analysis.

Journal: Thrombosis research 20121101

Title: Analysis of the projected utility of dabigatran, rivaroxaban, and apixaban and their future impact on existing Hematology and Cardiology Anticoagulation Clinics at The Johns Hopkins Hospital.

Journal: Journal of thrombosis and thrombolysis 20121101

Title: Hemorrhagic complications associated with dabigatran use.

Journal: Clinical toxicology (Philadelphia, Pa.) 20121101

Title: Effects on routine coagulation screens and assessment of anticoagulant intensity in patients taking oral dabigatran or rivaroxaban: guidance from the British Committee for Standards in Haematology.

Journal: British journal of haematology 20121101

Title: Interpretation of endpoints in a network meta-analysis of new oral anticoagulants following total hip or total knee replacement surgery.

Journal: Thrombosis and haemostasis 20121101

Title: Management consensus guidance for the use of rivaroxaban--an oral, direct factor Xa inhibitor.

Journal: Thrombosis and haemostasis 20121101

Title: [New anticoagulants - direct thrombin inhibitors].

Journal: Therapeutische Umschau. Revue therapeutique 20121101

Title: [Laboratory diagnostic with regard to new anticoagulants - monitoring and influence on coagulation tests].

Journal: Therapeutische Umschau. Revue therapeutique 20121101

Title: [Clinical pharmacological aspects of new oral anticoagulants].

Journal: Therapeutische Umschau. Revue therapeutique 20121101

Title: Mechanical valve thrombosis with dabigatran.

Journal: Journal of the American College of Cardiology 20121023

Title: How I treat anticoagulated patients undergoing an elective procedure or surgery.

Journal: Blood 20121011

Title: Prevention of stroke in patients with atrial fibrillation: anticoagulant and antiplatelet options.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20121001

Title: Value-of-information analysis to reduce decision uncertainty associated with the choice of thromboprophylaxis after total hip replacement in the Irish healthcare setting.

Journal: PharmacoEconomics 20121001

Title: Adjusted indirect comparison of new oral anticoagulants for stroke prevention in atrial fibrillation.

Journal: QJM : monthly journal of the Association of Physicians 20121001

Title: Determination of the anti-F10a or anti-F2a generation action of rivaroxaban or dabigatran.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20121001

Title: Anticoagulants in atrial fibrillation patients with chronic kidney disease.

Journal: Nature reviews. Nephrology 20121001

Title: A comparison of bleeding complications post-ablation between warfarin and dabigatran.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20121001

Title: Atrial fibrillation in long term care.

Journal: Journal of the American Medical Directors Association 20121001

Title: Dabigatran versus rivaroxaban for the prevention of stroke and systemic embolism in atrial fibrillation in Canada. Comparative efficacy and cost-effectiveness.

Journal: Thrombosis and haemostasis 20121001

Title: Home-monitoring of oral anticoagulation vs. dabigatran. An indirect comparison.

Journal: Thrombosis and haemostasis 20121001

Title: Dabigatran: laboratory monitoring.

Journal: Pathology 20121001

Title: New anticoagulants for stroke prophylaxis in atrial fibrillation: assessing the impact on medication adherence.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20121001

Title: New anticoagulants: A concise review.

Journal: The journal of trauma and acute care surgery 20121001

Title: Reversal of dabigatran-induced bleeding with a prothrombin complex concentrate and fresh frozen plasma.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20121001

Title: [Prophylaxis of thromboembolic events following hip and knee replacement: dabigatran, rivaroxaban or apixaban in comparison to enoxaparin].

Journal: Der Unfallchirurg 20121001

Title: What did we learn from new oral anticoagulant treatment?

Journal: Thrombosis research 20121001

Title: Antithrombotic treatment of atrial fibrillation: new insights.

Journal: Thrombosis research 20121001

Title: Do new oral anticoagulants require laboratory monitoring? The clinician point of view.

Journal: Thrombosis research 20121001

Title: Dabigatran in clinical practice.

Journal: Clinical therapeutics 20121001

Title: The new oral anticoagulants and the future of haemostasis laboratory testing.

Journal: Biochemia medica 20121001

Title: Dabigatran and thrombolysis: A therapeutic dilemma.

Journal: Annals of neurology 20121001

Title: [Dabigatran etexilate in clinical practice for prevention of thromboembolic events in patients with atrial fibrillation].

Journal: Vnitrni lekarstvi 20121001

Title: Safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing ablation for atrial fibrillation.

Journal: Journal of the American College of Cardiology 20120918

Title: ACP Journal Club. Review: new oral anticoagulants reduced stroke and systemic embolism compared with warfarin in AF.

Journal: Annals of internal medicine 20120918

Title: The safety risks of innovation: the FDA's Expedited Drug Development Pathway.

Journal: JAMA 20120905

Title: Dabigatran etexilate in atrial fibrillation patients with severe renal impairment: dose identification using pharmacokinetic modeling and simulation.

Journal: Journal of clinical pharmacology 20120901

Title: Atrial fibrillation and heart failure in the elderly.

Journal: Heart failure reviews 20120901

Title: Decrease in the oral bioavailability of dabigatran etexilate after co-medication with rifampicin.

Journal: British journal of clinical pharmacology 20120901

Title: Stroke prophylaxis with warfarin or dabigatran for patients with non-valvular atrial fibrillation-cost analysis.

Journal: Age and ageing 20120901

Title: Novel oral anticoagulation in management of venous thromboembolism, atrial fibrillation, and acute coronary syndrome.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20120901

Title: Dabigatran: comparison to warfarin, pathway to approval, and practical guidelines for use.

Journal: Journal of cardiovascular pharmacology and therapeutics 20120901

Title: Antithrombotic options for atrial fibrillation in 2012.

Journal: Cardiovascular & hematological disorders drug targets 20120901

Title: Treatment of venous thromboembolism with dabigatran.

Journal: Current opinion in pulmonary medicine 20120901

Title: Evaluation of the acute coronary syndrome safety profile of dabigatran etexilate in patients undergoing major orthopedic surgery: findings from four Phase 3 trials.

Journal: Thrombosis research 20120901

Title: Anticoagulants for the treatment of acute coronary syndrome in the era of new oral agents.

Journal: Coronary artery disease 20120901

Title: Dabigatran etexilate: a pharmacoeconomic review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation.

Journal: PharmacoEconomics 20120901

Title: The management of antithrombotic medication in skin surgery.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20120901

Title: Spontaneous gross haematuria during dabigatran therapy for secondary stroke prevention.

Journal: Thrombosis and haemostasis 20120901

Title: An indirect comparison of dabigatran, rivaroxaban and apixaban for atrial fibrillation.

Journal: Thrombosis and haemostasis 20120901

Title: Letter by Stollberger and Finsterer regarding article, 'intracranial hemorrhage in patients with atrial fibrillation during anticoagulation with Warfarin or Dabigatran: the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial'.

Journal: Stroke 20120901

Title: Life-threatening bleeding in four patients with an unusual excessive response to dabigatran: implications for emergency surgery and resuscitation.

Journal: Thrombosis and haemostasis 20120901

Title: Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model.

Journal: Journal of thrombosis and haemostasis : JTH 20120901

Title: Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate.

Journal: Journal of thrombosis and haemostasis : JTH 20120901

Title: Safe use of hemodialysis for dabigatran removal before cardiac surgery.

Journal: The Annals of pharmacotherapy 20120901

Title: Newer oral anticoagulants: a review of laboratory monitoring options and reversal agents in the hemorrhagic patient.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120901

Title: Systematic review and adjusted indirect comparison meta-analysis of oral anticoagulants in atrial fibrillation.

Journal: Circulation. Cardiovascular quality and outcomes 20120901

Title: The novel oral anticoagulants: an update for the interventional radiologist.

Journal: AJR. American journal of roentgenology 20120901

Title: [The new anticoagulants - their role in secondary prevention of thromboembolism after stroke].

Journal: Therapeutische Umschau. Revue therapeutique 20120901

Title: National trends in oral anticoagulant use in the United States, 2007 to 2011.

Journal: Circulation. Cardiovascular quality and outcomes 20120901

Title: The promise of novel direct oral anticoagulants.

Journal: Best practice & research. Clinical haematology 20120901

Title: Perioperative management of dabigatran: the Nelson experience to date.

Journal: The New Zealand medical journal 20120824

Title: Indirect comparisons of new oral anticoagulant drugs for efficacy and safety when used for stroke prevention in atrial fibrillation.

Journal: Journal of the American College of Cardiology 20120821

Title: Danger ahead: watch out for indirect comparisons!

Journal: Journal of the American College of Cardiology 20120821

Title: Thrombosis of a mechanical heart valve despite dabigatran.

Journal: Annals of internal medicine 20120821

Title: A new era of antithrombotic therapy in patients with atrial fibrillation.

Journal: The American journal of the medical sciences 20120801

Title: Dabigatran, rivaroxaban and apixaban versus enoxaparin for thomboprophylaxis after total knee or hip arthroplasty: pool-analysis of phase III randomized clinical trials.

Journal: Thrombosis research 20120801

Title: Acute stroke management in patients taking dabigatran.

Journal: CNS neuroscience & therapeutics 20120801

Title: Meta-analysis of efficacy and safety of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus warfarin in patients with atrial fibrillation.

Journal: The American journal of cardiology 20120801

Title: Novel anticoagulants for non-valvular atrial fibrillation.

Journal: Heart, lung & circulation 20120801

Title: Oral IIa and Xa inhibitors for prevention of stroke in atrial fibrillation: clinical studies and regulatory considerations.

Journal: Current clinical pharmacology 20120801

Title: Prevention and treatment of venous thromboembolism and pulmonary embolism: the role of novel oral anticoagulants.

Journal: Current clinical pharmacology 20120801

Title: The Food and Drug Administration decision not to approve the 110 mg dose of dabigatran: give us a way out.

Journal: The American journal of medicine 20120801

Title: Spontaneous ascending aortic intramural haematoma in a patient on dabigatran.

Journal: Interactive cardiovascular and thoracic surgery 20120801

Title: Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers.

Journal: Thrombosis and haemostasis 20120801

Title: Anticoagulation-related intracranial hemorrhages.

Journal: Current atherosclerosis reports 20120801

Title: FDA drug safety communications: a narrative review and clinical considerations for older adults.

Journal: The American journal of geriatric pharmacotherapy 20120801

Title: Cost-effectiveness of stroke treatments and secondary preventions.

Journal: Expert opinion on pharmacotherapy 20120801

Title: Reverse engineering for new oral anticoagulants: non-specific reversal agents and the anticoagulant activity of dabigatran and rivaroxaban.

Journal: Thrombosis and haemostasis 20120801

Title: Fatal gastrointestinal hemorrhage after a single dose of dabigatran.

Journal: Clinical toxicology (Philadelphia, Pa.) 20120801

Title: Comparison of efficacy and safety of dabigatran, rivaroxaban and apixaban in patients with atrial fibrillation using network meta-analysis.

Journal: International angiology : a journal of the International Union of Angiology 20120801

Title: Complications of anticoagulation.

Journal: Disease-a-month : DM 20120801

Title: [New oral anticoagulants for the prevention of stroke. Open questions in geriatric patients].

Journal: Zeitschrift fur Gerontologie und Geriatrie 20120801

Title: Emerging oral anticoagulants for stroke prevention in patients with non-valvular atrial fibrillation.

Journal: Minerva cardioangiologica 20120801

Title: Atraumatic acute carpal tunnel syndrome in a patient taking dabigatran.

Journal: Orthopedics 20120801

Title: Periprocedural anticoagulant management.

Journal: Hospital practice (1995) 20120801

Title: Target-specific oral anticoagulants for stroke prevention in patients with atrial fibrillation: real-world considerations.

Journal: Hospital practice (1995) 20120801

Title: The new oral anticoagulants: a challenge for hospital formularies.

Journal: Hospital practice (1995) 20120801

Title: Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial.

Journal: Circulation 20120717

Title: Anticoagulation, novel agents, and procedures: can we pardon the interruption?

Journal: Circulation 20120717

Title: Epistaxis associated with dabigatran in an elderly patient with reduced creatinine clearance.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120715

Title: Dabigatran: uncharted waters and potential harms.

Journal: Annals of internal medicine 20120703

Title: New oral anticoagulants for atrial fibrillation.

Journal: Circulation 20120703

Title: Thrombotic events after discontinuing dabigatran: rebound or resumption?

Journal: BMJ (Clinical research ed.) 20120703

Title: Renal profiles of anticoagulants.

Journal: Journal of clinical pharmacology 20120701

Title: Pharmacologic and nonpharmacologic therapies for stroke prevention in nonvalvular atrial fibrillation.

Journal: Pacing and clinical electrophysiology : PACE 20120701

Title: Dabigatran etexilate and concomitant use of non-steroidal anti-inflammatory drugs or acetylsalicylic acid in patients undergoing total hip and total knee arthroplasty: no increased risk of bleeding.

Journal: Thrombosis and haemostasis 20120701

Title: Letter by Freeman et al regarding article, 'Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY Trial'.

Journal: Stroke 20120701

Title: Comparative efficacy and safety of new oral anticoagulants in patients with atrial fibrillation.

Journal: Circulation. Cardiovascular quality and outcomes 20120701

Title: Evaluating and assessing dabigatran drug interactions.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20120701

Title: Dabigatran in recurrent deep vein thrombosis: when one-size does not fit all.

Journal: The Israel Medical Association journal : IMAJ 20120701

Title: Faculty of Consulting Physicians of South Africa (FCPSA): saving brain with dabigatran.

Journal: Cardiovascular journal of Africa 20120701

Title: Dabigatran: rational dose individualisation and monitoring guidance is needed.

Journal: The New Zealand medical journal 20120629

Title: ACP Journal Club. Review: Dabigatran increases MI and reduces mortality compared with warfarin, enoxaparin, or placebo.

Journal: Annals of internal medicine 20120619

Title: Epidural hematoma and intraoperative hemorrhage in a spine trauma patient on Pradaxa (dabigatran).

Journal: Spine 20120615

Title: New oral anticoagulants for venous thromboembolism: focus on factor Xa and thrombin inhibitors.

Journal: Current drug discovery technologies 20120601

Title: Discovery of anticoagulant drugs: a historical perspective.

Journal: Current drug discovery technologies 20120601

Title: Management of postoperative atrial fibrillation.

Journal: Journal of anesthesia 20120601

Title: Dabigatran or warfarin for the prevention of stroke in atrial fibrillation? A closer look at the RE-LY trial.

Journal: Expert opinion on pharmacotherapy 20120601

Title: New anticoagulant drugs for treatment of venous thromboembolism and stroke prevention in atrial fibrillation.

Journal: Journal of internal medicine 20120601

Title: Anti-stroke prophylaxis--the ethics of collateral damage.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120601

Title: Dabigatran: a new chapter in anticoagulation.

Journal: Cardiovascular & hematological agents in medicinal chemistry 20120601

Title: Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial.

Journal: Stroke 20120601

Title: Long-term benefits of preventing venous thromboembolic events.

Journal: Current medical research and opinion 20120601

Title: [New anticoagulant drugs for atrial fibrillation. Feasibility and necessity of monitoring].

Journal: Herz 20120601

Title: [Pharmacology of the new oral anticoagulants].

Journal: Herz 20120601

Title: [Role of the new oral anticoagulants in comparison to vitamin K antagonists in practice].

Journal: Herz 20120601

Title: Dabigatran for the prevention of stroke in atrial fibrillation: is RE-LY reliable?

Journal: Expert opinion on pharmacotherapy 20120601

Title: Dabigatran versus warfarin after mechanical mitral valve replacement in the swine model.

Journal: Journal of investigative surgery : the official journal of the Academy of Surgical Research 20120601

Title: [Anticoagulation. Modern concepts].

Journal: Herz 20120601

Title: Current and future alternatives to warfarin for the prevention of stroke in atrial fibrillation.

Journal: Critical pathways in cardiology 20120601

Title: A guidance pathway for the selection of novel anticoagulants in the treatment of atrial fibrillation.

Journal: Critical pathways in cardiology 20120601

Title: An audience with... Gregory Lip. Interview by Asher Mullard.

Journal: Nature reviews. Drug discovery 20120601

Title: Rectal bleeding and hemostatic disorders induced by dabigatran etexilate in 2 elderly patients.

Journal: The Annals of pharmacotherapy 20120601

Title: An anticoagulation option for nonvalvular atrial fibrillation.

Journal: The Journal of family practice 20120601

Title: Novel oral anticoagulants for stroke prevention in atrial fibrillation: focus on apixaban.

Journal: Advances in therapy 20120601

Title: Dabigatran for the prevention of thromboembolic complications in the elderly: a RE-LY-able alternative to warfarin?

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20120601

Title: A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: THE Randomized, phase II study to evaluate the safety and pharmacokinetics of oral dabigatran etexilate in patients after heart valve replacement (RE-ALIGN).

Journal: American heart journal 20120601

Title: New anticoagulant fights for credibility.

Journal: Managed care (Langhorne, Pa.) 20120601

Title: Novel oral anticoagulants for stroke prevention in atrial fibrillation.

Journal: European heart journal 20120601

Title: Dabigatran and myocardial infarction: meta-illusion?

Journal: Archives of internal medicine 20120528

Title: [Series: Clinical study from Japan and its reflections RE-LY trial].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20120510

Title: Anticoagulant therapy for patients with ischaemic stroke.

Journal: Nature reviews. Neurology 20120508

Title: Dabigatran etexilate: a review of its use for the prevention of venous thromboembolism after total hip or knee replacement surgery.

Journal: Drugs 20120507

Title: Switching from enoxaparin to dabigatran etexilate: pharmacokinetics, pharmacodynamics, and safety profile.

Journal: European journal of clinical pharmacology 20120501

Title: Dabigatran efficacy-safety assessment for stroke prevention in patients with atrial fibrillation.

Journal: Journal of thrombosis and haemostasis : JTH 20120501

Title: Neurosurgical complications of direct thrombin inhibitors--catastrophic hemorrhage after mild traumatic brain injury in a patient receiving dabigatran.

Journal: Journal of neurosurgery 20120501

Title: Tissue factor-driven thrombin generation and inflammation in atherosclerosis.

Journal: Thrombosis research 20120501

Title: Impact of dabigatran on a large panel of routine or specific coagulation assays. Laboratory recommendations for monitoring of dabigatran etexilate.

Journal: Thrombosis and haemostasis 20120501

Title: Thrombolysis with recombinant tissue plasminogen activator under dabigatran anticoagulation in experimental stroke.

Journal: Annals of neurology 20120501

Title: Letter by Van de Werf et al regarding article, 'using dabigatran in patients with stroke: a practical guide for clinicians'.

Journal: Stroke 20120501

Title: Letter by Casado-Naranjo et al regarding article, 'using dabigatran in patients with stroke: a practical guide for clinicians'.

Journal: Stroke 20120501

Title: Letter by Freeman et al regarding article, 'using dabigatran in patients with stroke: a practical guide for clinicians'.

Journal: Stroke 20120501

Title: Advances in laboratory testing for thrombophilia.

Journal: American journal of hematology 20120501

Title: Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors.

Journal: American journal of hematology 20120501

Title: Hemopericardium in a patient treated with dabigatran etexilate.

Journal: Pharmacotherapy 20120501

Title: Implementing the new oral anticoagulants into the hospital formulary.

Journal: American journal of hematology 20120501

Title: Fatal basilar artery occlusion under dabigatran occurring 13 days after femoral embolectomy.

Journal: Vascular and endovascular surgery 20120501

Title: Novel oral anticoagulants--key messages for the angiologist.

Journal: VASA. Zeitschrift fur Gefasskrankheiten 20120501

Title: Dabigatran in patients with atrial fibrillation: perioperative and periinterventional management.

Journal: Wiener klinische Wochenschrift 20120501

Title: New oral anticoagulants: will they replace warfarin?

Journal: Oral surgery, oral medicine, oral pathology and oral radiology 20120501

Title: Oral anticoagulants for atrial fibrillation: Which one to choose?

Journal: Advance for NPs & PAs 20120501

Title: Newer oral anticoagulant agents: a new era in medicine.

Journal: Current cardiology reviews 20120501

Title: Prescribing trends for dabigatran etexilate in primary care.

Journal: Irish medical journal 20120501

Title: [The monitoring of application of dabigatran as a remedy of prevention of thromboembolic complications after hip joint arthroplasty].

Journal: Klinicheskaia laboratornaia diagnostika 20120501

Title: Dabigatran and dabigatran ethyl ester: potent inhibitors of ribosyldihydronicotinamide dehydrogenase (NQO2).

Journal: Journal of medicinal chemistry 20120426

Title: Letter by Bernstein et al regarding article, 'reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects.

Journal: Circulation 20120424

Title: Letter by Marlu et al regarding article, 'reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects'.

Journal: Circulation 20120424

Title: New oral anticoagulants in atrial fibrillation and acute coronary syndromes: ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease position paper.

Journal: Journal of the American College of Cardiology 20120417

Title: Dabigatran is not a direct Xa inhibitor.

Journal: Journal of the American College of Cardiology 20120417

Title: Avoiding adverse events with dabigatran by careful selection of eligible patients.

Journal: The Medical journal of Australia 20120416

Title: New medicines - urgent need to assess outcomes in special groups.

Journal: The Medical journal of Australia 20120416

Title: Endovascular therapy after stroke in a patient treated with dabigatran.

Journal: The Medical journal of Australia 20120416

Title: Novel anticoagulants for atrial fibrillation: a critical appraisal.

Journal: Angiology 20120401

Title: Planning and monitoring of patients for electrical cardioversion for atrial fibrillation.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20120401

Title: Thromboprophylaxis in patients older than 75 years or with moderate renal impairment undergoing knee or hip replacement surgery [corrected].

Journal: International orthopaedics 20120401

Title: Interpretation of point-of-care INR results in patients treated with dabigatran.

Journal: The American journal of medicine 20120401

Title: Fluorinated dual antithrombotic compounds based on 1,4-benzoxazine scaffold.

Journal: European journal of medicinal chemistry 20120401

Title: New insights in prevention, diagnosis and treatment of stroke: its relation with atrial fibrillation.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20120401

Title: Clinical challenges in a patient with dabigatran-induced fatal hemorrhage.

Journal: The American journal of geriatric pharmacotherapy 20120401

Title: A combined pharmacometric analysis of dabigatran etexilate in healthy volunteers and patients with atrial fibrillation or undergoing orthopaedic surgery.

Journal: Thrombosis and haemostasis 20120401

Title: New oral anticoagulants for atrial fibrillation: a review of clinical trials.

Journal: Clinical therapeutics 20120401

Title: Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in UK patients with atrial fibrillation.

Journal: Heart (British Cardiac Society) 20120401

Title: Plasma-diluted thrombin time to measure dabigatran concentrations during dabigatran etexilate therapy.

Journal: American journal of clinical pathology 20120401

Title: Dabigatran and factor Xa inhibitors for stroke prevention in patients with nonvalvular atrial fibrillation.

Journal: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20120401

Title: Dabigatran etexilate: an oral direct thrombin inhibitor for the management of thromboembolic disorders.

Journal: Clinical therapeutics 20120401

Title: Thromboembolic prophylaxis in orthopedic surgery using dabigatran: an oral direct thrombin inhibitor.

Journal: Expert review of cardiovascular therapy 20120401

Title: Aspirin in stroke prevention in nonvalvular atrial fibrillation and stable vascular disease: an era of new anticoagulants.

Journal: Expert review of cardiovascular therapy 20120401

Title: Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment.

Journal: The Annals of pharmacotherapy 20120401

Title: [Novel oral anticoagulants and their use in the perioperative setting].

Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20120401

Title: Beyond warfarin: the new generation of oral anticoagulants and their implications for the management of dental patients.

Journal: Oral surgery, oral medicine, oral pathology and oral radiology 20120401

Title: How I treat with anticoagulants in 2012: new and old anticoagulants, and when and how to switch.

Journal: Blood 20120329

Title: Anticoagulation for atrial fibrillation ablation: what is the optimal strategy?

Journal: Journal of the American College of Cardiology 20120327

Title: Feasibility and safety of dabigatran versus warfarin for periprocedural anticoagulation in patients undergoing radiofrequency ablation for atrial fibrillation: results from a multicenter prospective registry.

Journal: Journal of the American College of Cardiology 20120327

Title: Progress for stroke prevention with atrial fibrillation: emergence of alternative oral anticoagulants.

Journal: Circulation 20120327

Title: [Prophylaxis of stroke and embolisms in atrial fibrillation--what is new in the guidelines?].

Journal: MMW Fortschritte der Medizin 20120322

Title: Anticoagulation therapy. Dabigatran and risk of myocardial infarction.

Journal: Nature reviews. Cardiology 20120313

Title: Important data after drug approval: comment on 'Dabigatran association with higher risk of acute coronary events'.

Journal: Archives of internal medicine 20120312

Title: Dabigatran: do we have sufficient data?: comment on 'Dabigatran association with higher risk of acute coronary events'.

Journal: Archives of internal medicine 20120312

Title: Dabigatran association with higher risk of acute coronary events: meta-analysis of noninferiority randomized controlled trials.

Journal: Archives of internal medicine 20120312

Title: National prescribing data for dabigatran.

Journal: The New Zealand medical journal 20120309

Title: Dabigitran and the radiology department.

Journal: Irish journal of medical science 20120301

Title: The use of dabigatran immediately after atrial fibrillation ablation.

Journal: Journal of cardiovascular electrophysiology 20120301

Title: What's a mother to do?

Journal: Journal of cardiovascular electrophysiology 20120301

Title: Dabigatran etexilate: what do hospitalists need to know?

Journal: Journal of hospital medicine 20120301

Title: Net clinical benefit of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus no treatment in a 'real world' atrial fibrillation population: a modelling analysis based on a nationwide cohort study.

Journal: Thrombosis and haemostasis 20120301

Title: Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20120301

Title: Old and new oral anticoagulants for venous thromboembolism and atrial fibrillation: a review of the literature.

Journal: Thrombosis research 20120301

Title: Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in patients with atrial fibrillation and prior stroke or transient ischemic attack.

Journal: Stroke 20120301

Title: What's the 'go to' anticoagulant for stroke prevention in atrial fibrillation?

Journal: Thrombosis and haemostasis 20120301

Title: New directions in anticoagulation.

Journal: The American journal of medicine 20120301

Title: Dabigatran (Pradaxa).

Journal: AJNR. American journal of neuroradiology 20120301

Title: A new generation of oral direct anticoagulants.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120301

Title: Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20120301

Title: [Controversy. Dabigatran in the preventive treatment of embolic stroke: arguments in favour of its utilisation as a first-choice drug].

Journal: Revista de neurologia 20120301

Title: [Controversy. Dabigatran in the preventive treatment of embolic stroke: arguments against its utilisation as a first-choice drug].

Journal: Revista de neurologia 20120301

Title: Is dabigatran cost effective compared with warfarin for stroke prevention in atrial fibrillation? A critically appraised topic.

Journal: The neurologist 20120301

Title: More on acutely injured patients receiving dabigatran.

Journal: The New England journal of medicine 20120301

Title: Bleeding risk with dabigatran in the frail elderly.

Journal: The New England journal of medicine 20120301

Title: Dabigatran (OCTOBER 2011).

Journal: Cleveland Clinic journal of medicine 20120301

Title: Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding.

Journal: Blood 20120301

Title: [Clinical studies, the interests and limits of using dabigatran in atrial fibrillation].

Journal: Journal de pharmacie de Belgique 20120301

Title: [Pharmacological sheet. Dabigatran, oral administration (Pradaxa)].

Journal: Journal de pharmacie de Belgique 20120301

Title: The efficacy and safety of postoperative autologous transfusion of filtered shed blood and anticoagulant prophylaxis in total knee arthroplasty patients.

Journal: Knee surgery & related research 20120301

Title: [Prevention of cardioembolic stroke].

Journal: Neurologia (Barcelona, Spain) 20120301

Title: [Dabigatran: a new therapeutic alternative in the prevention of stroke].

Journal: Neurologia (Barcelona, Spain) 20120301

Title: Efficacy and safety of dabigatran compared to warfarin in patients with paroxysmal, persistent, and permanent atrial fibrillation: results from the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) study.

Journal: Journal of the American College of Cardiology 20120227

Title: Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial.

Journal: Circulation 20120207

Title: Heparin-induced thrombocytopenia: in vitro studies on the interaction of dabigatran, rivaroxaban, and low-sulfated heparin, with platelet factor 4 and anti-PF4/heparin antibodies.

Journal: Blood 20120202

Title: HIT: treatment easier, prevention harder.

Journal: Blood 20120202

Title: Incidence and management of ischemic stroke and intracerebral hemorrhage in patients on dabigatran etexilate treatment.

Journal: Neurocritical care 20120201

Title: Anticoagulant management in the cardiovascular setting.

Journal: Fundamental & clinical pharmacology 20120201

Title: Rivaroxaban for the prevention and treatment of venous thromboembolism.

Journal: Fundamental & clinical pharmacology 20120201

Title: New anticoagulants for the prevention of stroke in atrial fibrillation.

Journal: Fundamental & clinical pharmacology 20120201

Title: Preventing cardioembolic stroke in atrial fibrillation with dabigatran.

Journal: Current neurology and neuroscience reports 20120201

Title: Lack of an antagonist to reverse the action of dabigatran.

Journal: QJM : monthly journal of the Association of Physicians 20120201

Title: The management of anticoagulants perioperatively.

Journal: Thoracic surgery clinics 20120201

Title: Promise of factor Xa inhibition in atrial fibrillation.

Journal: Current cardiology reports 20120201

Title: First cascade Mitsunobu reactions for the synthesis of 2-benzoxazole-N-phenyl and 2-benzimidazole-N-phenyl derivatives.

Journal: Molecular diversity 20120201

Title: Dabigatran for patients with a mechanical valve.

Journal: Heart, lung & circulation 20120201

Title: Stroke prevention in atrial fibrillation: do we still need warfarin?

Journal: Current opinion in neurology 20120201

Title: Dabigatran etexilate for the prevention of venous thromboembolism in patients undergoing elective hip or knee surgery: a NICE single technology appraisal.

Journal: PharmacoEconomics 20120201

Title: Management of coagulation: an Australian perspective.

Journal: Current opinion in anaesthesiology 20120201

Title: Pharmacokinetics and pharmacodynamics in Japanese and Caucasian subjects after oral administration of dabigatran etexilate.

Journal: Thrombosis and haemostasis 20120201

Title: A new approach with anticoagulant development: tailoring anticoagulant therapy with dabigatran etexilate according to patient risk.

Journal: Expert opinion on pharmacotherapy 20120201

Title: Stroke prevention in atrial fibrillation.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20120201

Title: Cost-effectiveness of pharmacologic and invasive therapies for stroke prophylaxis in atrial fibrillation.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20120201

Title: Twice daily dosing of dabigatran for stroke prevention in atrial fibrillation: a pharmacokinetic justification.

Journal: Current medical research and opinion 20120201

Title: The year in Cardiothoracic and Vascular Anesthesia: selected highlights from 2011.

Journal: Journal of cardiothoracic and vascular anesthesia 20120201

Title: Using anticoagulants to steer clear of clots.

Journal: Nursing 20120201

Title: Application of the RELY study to lifetime risks of atrial fibrillation: implications for spontaneous intracranial hemorrhage.

Journal: Neurosurgery 20120201

Title: The king is dead (warfarin): direct thrombin and factor Xa inhibitors: the next Diadochian War?

Journal: International journal of stroke : official journal of the International Stroke Society 20120201

Title: Letter by Moll regarding article, 'Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran'.

Journal: Stroke 20120201

Title: Direct thrombin inhibitors and factor Xa inhibitors in patients with cerebrovascular disease.

Journal: Expert review of neurotherapeutics 20120201

Title: The oral thrombin inhibitor dabigatran: strengths and weaknesses.

Journal: Seminars in thrombosis and hemostasis 20120201

Title: Determination of dabigatran in human plasma samples.

Journal: Seminars in thrombosis and hemostasis 20120201

Title: Active online assessment of patients using new oral anticoagulants: bleeding risk, compliance, and coagulation analysis.

Journal: Seminars in thrombosis and hemostasis 20120201

Title: Prevention of embolic strokes: the role of the American College of Chest Physicians.

Journal: Chest 20120201

Title: Prevention of VTE in orthopedic surgery patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Antithrombotic therapy for atrial fibrillation: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Journal: Chest 20120201

Title: Warfarin versus dabigatran: comparing the old with the new.

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20120201

Title: Dabigatran product familiarisation programmes: who benefits, who shouldn't get it?

Journal: Internal medicine journal 20120201

Title: Dabigatran and atrial fibrillation: the alternative to warfarin for selected patients.

Journal: Prescrire international 20120201

Title: Acute cardioembolic cerebral infarction: answers to clinical questions.

Journal: Current cardiology reviews 20120201

Title: Anticoagulant loses its lustre.

Journal: Lancet (London, England) 20120128

Title: Switching patients from warfarin to dabigatran therapy: to RE-LY or not to rely.

Journal: International journal of cardiology 20120126

Title: UPLC MS/MS assay for routine quantification of dabigatran - a direct thrombin inhibitor - in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20120125

Title: Letter by Govindarajan and Salgado regarding article, 'Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial'.

Journal: Circulation 20120124

Title: Letter by Reynolds et al regarding article, 'Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial'.

Journal: Circulation 20120124

Title: Letter by Reiffel regarding article, 'Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial'.

Journal: Circulation 20120124

Title: [Expanded arsenal in atrial fibrillation: bye-bye marcumar?].

Journal: MMW Fortschritte der Medizin 20120119

Title: New anticoagulants - promising and failed developments.

Journal: British journal of pharmacology 20120101

Title: Hospital budget implications of substituting dabigatran for warfarin in an anticoagulation service.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20120101

Title: Thrombosis on a Mechanical Aortic Valve whilst Anti-coagulated With Dabigatran.

Journal: Heart, lung & circulation 20120101

Title: Clinical pharmacology basis of deriving dosing recommendations for dabigatran in patients with severe renal impairment.

Journal: Journal of clinical pharmacology 20120101

Title: Stroke prevention in elderly patients with atrial fibrillation: challenges for anticoagulation.

Journal: Journal of internal medicine 20120101

Title: Intravenous tissue plasminogen activator treatment for ischemic stroke in dabigatran-treated patients.

Journal: Acta neurochirurgica 20120101

Title: Effects of dabigatran in vitro on thrombin biomarkers by Calibrated Automated Thrombography in patients after ischemic stroke.

Journal: Journal of thrombosis and thrombolysis 20120101

Title: Effect of pharmacological therapies for stroke prevention on major gastrointestinal bleeding in patients with atrial fibrillation.

Journal: International journal of clinical practice 20120101

Title: Concerns about studies investigating new anticoagulant drugs for stroke prevention in atrial fibrillation.

Journal: Journal of neurology 20120101

Title: [Anticoagulation in atrial fibrillation: a new era has begun].

Journal: Hamostaseologie 20120101

Title: [Anticoagulation for atrial fibrillation : the future has begun].

Journal: Der Internist 20120101

Title: Using dabigatran in patients with stroke: a practical guide for clinicians.

Journal: Stroke 20120101

Title: Dabigatran use in a postoperative coronary artery bypass surgery patient with nonvalvular atrial fibrillation and heparin-PF4 antibodies.

Journal: The Annals of pharmacotherapy 20120101

Title: Two distinct coagulase-dependent barriers protect Staphylococcus aureus from neutrophils in a three dimensional in vitro infection model.

Journal: PLoS pathogens 20120101

Title: New frontiers for stroke prevention in atrial fibrillation.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20120101

Title: Dabigatran in clinical practice for atrial fibrillation with special reference to activated partial thromboplastin time.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: ARISTOTLE RE-LYs on the ROCKET. What's new in stroke prevention in patients with atrial fibrillation?

Journal: Cardiology journal 20120101

Title: [Pharmacoeconomic analysis of dabigatran etexilate effectiveness in patients with nonvalvular atrial fibrillation].

Journal: Kardiologiia 20120101

Title: New antiplatelet and anticoagulant drugs.

Journal: General dentistry 20120101

Title: Anticoagulation prophylaxis in orthopedic surgery: an efficiency frontier approach.

Journal: Postgraduate medicine 20120101

Title: New oral antithrombotics: focus on dabigatran, an oral, reversible direct thrombin inhibitor for the prevention and treatment of venous and arterial thromboembolic disorders.

Journal: Vascular health and risk management 20120101

Title: I recently heard that there are alternative medications to the blood thinner warfarin. What are they, and how are they different?

Journal: DukeMedicine healthnews 20120101

Title: Monitoring of the effects of new-generation oral anticoagulants – what does it mean? – .

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: A new era for anticoagulation in atrial fibrillation. Which anticoagulant should we choose for long‑term prevention of thromboembolic complications in patients with atrial fibrillation?

Journal: Polskie Archiwum Medycyny Wewnetrznej 20120101

Title: Report on the 3'rd scientific meeting of the 'Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie' (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011.

Journal: Experimental & translational stroke medicine 20120101

Title: Newer anticoagulants in cardiovascular disease: a systematic review of the literature.

Journal: Cardiology in review 20120101

Title: Improving prevention and treatment of venous thromboembolism: clinical trial results.

Journal: Journal of medical economics 20120101

Title: The WATCHMAN left atrial appendage closure device for atrial fibrillation.

Journal: Journal of visualized experiments : JoVE 20120101

Title: Exfoliative esophagitis and esophageal ulcer induced by dabigatran.

Journal: Endoscopy 20120101

Title: Cost-effectiveness of dabigatran etexilate for stroke prevention in non-valvular atrial fibrillation. Applying RE-LY to clinical practice in Denmark.

Journal: Journal of medical economics 20120101

Title: Translatability scoring in drug development: eight case studies.

Journal: Journal of translational medicine 20120101

Title: Stroke Prevention in Atrial Fibrillation: Where are We Now?

Journal: Clinical Medicine Insights. Cardiology 20120101

Title: Cost considerations in the management of atrial fibrillation - impact of dronedarone.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: [Update on current care guidelines: atrial fibrillation].

Journal: Duodecim; laaketieteellinen aikakauskirja 20120101

Title: Medical cost reductions associated with the usage of novel oral anticoagulants vs warfarin among atrial fibrillation patients, based on the RE-LY, ROCKET-AF, and ARISTOTLE trials.

Journal: Journal of medical economics 20120101

Title: Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors.

Journal: PloS one 20120101

Title: Current status of new anticoagulants in the management of venous thromboembolism.

Journal: Advances in hematology 20120101

Title: Costs and clinical consequences of suboptimal atrial fibrillation management.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: Hitting back HIT.

Journal: Annals of cardiac anaesthesia 20120101

Title: Efficacy and safety of venous thromboembolism prophylaxis with apixaban in major orthopedic surgery.

Journal: Therapeutics and clinical risk management 20120101

Title: Economic evaluation of dabigatran etexilate for the primary prevention of venous tromboembolic events following major orthopedic surgery in the Netherlands.

Journal: Journal of medical economics 20120101

Title: The economic impact of enoxaparin versus unfractionated heparin for prevention of venous thromboembolism in acute ischemic stroke patients.

Journal: ClinicoEconomics and outcomes research : CEOR 20120101

Title: Preventing stroke in atrial fibrillation patients - clinical utility of oral anticoagulants.

Journal: Journal of blood medicine 20120101

Title: Anticoagulant and antiplatelet therapy in patients with atrial fibrillation and coronary artery disease.

Journal: Thrombosis 20120101

Title: [New antithrombotic drugs].

Journal: Duodecim; laaketieteellinen aikakauskirja 20120101

Title: [Dabigatran and emergency operation on a peritonitis patient].

Journal: Duodecim; laaketieteellinen aikakauskirja 20120101

Title: Advances in the diagnosis and treatment of acute pulmonary embolism.

Journal: F1000 medicine reports 20120101

Title: Reviewing the medical literature: five notable articles in general internal medicine from 2010 and 2011.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20120101

Title: Therapeutic dosing of acenocoumarol: proposal of a population specific pharmacogenetic dosing algorithm and its validation in north Indians.

Journal: PloS one 20120101

Title: Dabigatran for stroke prevention in nonvalvular atrial fibrillation: answers to challenging 'real-world' questions.

Journal: Thrombosis 20120101

Title: Non-pharmacological therapy for atrial fibrillation: managing the left atrial appendage.

Journal: Cardiology research and practice 20120101

Title: Dabigatran: a new anticoagulant for stroke prevention in patients with atrial fibrillation.

Journal: Missouri medicine 20120101

Title: Newer anticoagulants for the prevention of venous thromboembolism.

Journal: The National medical journal of India 20120101

Title: Dabigatran, rivaroxaban, or apixaban versus enoxaparin for thromboprophylaxis after total hip or knee replacement: systematic review, meta-analysis, and indirect treatment comparisons.

Journal: BMJ (Clinical research ed.) 20120101

Title: Rationale and design of XAMOS: noninterventional study of rivaroxaban for prophylaxis of venous thromboembolism after major hip and knee surgery.

Journal: Vascular health and risk management 20120101

Title: Health technology assessment and its role in the future development of the Indian healthcare sector.

Journal: Perspectives in clinical research 20120101

Title: Dabigatran for stroke prevention in atrial fibrillation.

Journal: Hamostaseologie 20120101

Title: Cost-effectiveness of dabigatran versus genotype-guided management of warfarin therapy for stroke prevention in patients with atrial fibrillation.

Journal: PloS one 20120101

Title: Pharmacokinetic and clinical implications of dabigatran use in severe renal impairment for stroke prevention in nonvalvular atrial fibrillation.

Journal: The Annals of pharmacotherapy 20120101

Title: Efficacy and safety of periprocedural dabigatran in patients undergoing catheter ablation of atrial fibrillation.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Can dabigatran be an alternative periprocedural anticoagulation for atrial fibrillation ablation?

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Hemopericardium and cardiac tamponade associated with dabigatran use.

Journal: The Annals of pharmacotherapy 20120101

Title: [New anticoagulants: dabigatran, rivaroxaban and apixaban].

Journal: Gaceta medica de Mexico 20120101

Title: An evidence-based review of apixaban and its potential in the prevention of stroke in patients with atrial fibrillation.

Journal: Core evidence 20120101

Title: Emerging anticoagulant therapies for atrial fibrillation: new options, new challenges.

Journal: Current medicinal chemistry 20120101

Title: [Comparison of three methods of antithrombotic therapy in elderly patients with nonvalvular atrial fibrillation].

Journal: Kardiologiia 20120101

Title: Agranulocytosis immediately after oral administration of cibenzoline and dabigatran in a patient with paroxysmal atrial fibrillation.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke.

Journal: PloS one 20120101

Title: Perioperative stroke risk in nonvascular surgery.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20120101

Title: Vitamin K antagonists. Ready to be replaced?

Journal: Hamostaseologie 20120101

Title: Understanding the new emerging oral anticoagulants for venous thromboembolism prophylaxis.

Journal: Orthopedic nursing 20120101

Title: Rivaroxaban in atrial fibrillation.

Journal: Vascular health and risk management 20120101

Title: Prevention of stroke and systemic embolization in atrial fibrillation: a Canadian perspective.

Journal: Polskie Archiwum Medycyny Wewnetrznej 20120101

Title: Diffuse alveolar hemorrhage associated with dabigatran.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Stroke prevention in atrial fibrillation: understanding the new oral anticoagulants dabigatran, rivaroxaban, and apixaban.

Journal: Thrombosis 20120101

Title: Stroke and thromboembolism in atrial fibrillation.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: [New oral anticoagulants for atrial fibrillation: a neurologist's view].

Journal: Nederlands tijdschrift voor geneeskunde 20120101

Title: Coronary and mortality risk of novel oral antithrombotic agents: a meta-analysis of large randomised trials.

Journal: BMJ open 20120101

Title: The ps in therapeutics.

Journal: International journal of pharmaceutical compounding 20120101

Title: [Therapeutic approach to the bleeding in association with 'old' and 'new' anticoagulants].

Journal: Vnitrni lekarstvi 20120101

Title: [Anticoagulant therapy in connection with cardioversion in patients with atrial fibrillation].

Journal: Kardiologiia 20120101

Title: Interference of the new oral anticoagulant dabigatran with frequently used coagulation tests.

Journal: Clinical chemistry and laboratory medicine 20120101

Title: [Dabigatran therapy--perioperative management and interpretation of coagulation tests].

Journal: Hamostaseologie 20120101

Title: Left atrial appendage exclusion for stroke prevention in atrial fibrillation.

Journal: Cardiology research and practice 20120101

Title: Bleeding with dabigatran (Pradaxa).

Journal: The Medical letter on drugs and therapeutics 20111212

Title: Antiplatelet agents and anticoagulants for hypertension.

Journal: The Cochrane database of systematic reviews 20111207

Title: Thromboembolism prophylaxis with dabigatran leads to lower perioperative blood loss than with dalteparin in primary knee arthroplasty.

Journal: Archives of orthopaedic and trauma surgery 20111201

Title: Dabigatran in atrial fibrillation: pharmacology and clinical trials.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20111201

Title: Effect of multiple doses of omeprazole on the pharmacokinetics, pharmacodynamics, and safety of a single dose of rivaroxaban.

Journal: Journal of cardiovascular pharmacology 20111201

Title: New anticoagulants: moving on from scientific results to clinical implementation.

Journal: Annals of medicine 20111201

Title: Dabigatran: review of pharmacology and management of bleeding complications of this novel oral anticoagulant.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20111201

Title: [New anticoagulants: 'efficacy and safety' or 'efficacy or safety'].

Journal: Journal des maladies vasculaires 20111201

Title: Advances in anticoagulation: focus on dabigatran, an oral direct thrombin inhibitor.

Journal: Journal of cardiothoracic and vascular anesthesia 20111201

Title: Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran.

Journal: Stroke 20111201

Title: Inhibition of staphylothrombin by dabigatran reduces Staphylococcus aureus virulence.

Journal: Journal of thrombosis and haemostasis : JTH 20111201

Title: Antithrombotic therapy in nonvalvular atrial fibrillation: a narrative review.

Journal: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology 20111201

Title: Dabigatran: a new oral anticoagulant.

Journal: Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 20111201

Title: Role of pharmacogenomics in the management of traditional and novel oral anticoagulants.

Journal: Pharmacotherapy 20111201

Title: Striking a balance between the risks and benefits of anticoagulation bridge therapy in patients with atrial fibrillation: clinical updates and remaining controversies.

Journal: Pharmacotherapy 20111201

Title: Dabigatran etexilate in clinical practice: confronting challenges to improve safety and effectiveness.

Journal: Pharmacotherapy 20111201

Title: Dabigatran (OCTOBER 2011).

Journal: Cleveland Clinic journal of medicine 20111201

Title: eComment: Anticoagulants after atrial fibrillation ablation: the potential use of dabigatran.

Journal: Interactive cardiovascular and thoracic surgery 20111201

Title: [Pharmacologic heterogeneity of new anticoagulants].

Journal: Journal des maladies vasculaires 20111201

Title: [New treatments for venous thromboembolic disease].

Journal: Journal des maladies vasculaires 20111201

Title: Dabigatran versus warfarin for patients with non-valvular atrial fibrillation: is the patient the winner?

Journal: Australian nursing journal (July 1993) 20111201

Title: Antithrombotic therapy for secondary stroke prevention.

Journal: Continuum (Minneapolis, Minn.) 20111201

Title: Acutely injured patients on dabigatran.

Journal: The New England journal of medicine 20111124

Title: Risks for stroke, bleeding, and death in patients with atrial fibrillation receiving dabigatran or warfarin in relation to the CHADS2 score: a subgroup analysis of the RE-LY trial.

Journal: Annals of internal medicine 20111115

Title: Learning the respective roles of warfarin and dabigatran to prevent stroke in patients with nonvalvular atrial fibrillation.

Journal: Annals of internal medicine 20111115

Title: Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial.

Journal: European heart journal 20111101

Title: Redemption by RE-DEEM?

Journal: European heart journal 20111101

Title: Bleeding, vertebral fractures and vascular calcifications in patients treated with warfarin: hope for lower risks with alternative therapies.

Journal: Current vascular pharmacology 20111101

Title: External and internal validity of open label or double-blind trials in oral anticoagulation: better, worse or just different?

Journal: Journal of thrombosis and haemostasis : JTH 20111101

Title: Questions and answers on the use of dabigatran and perspectives on the use of other new oral anticoagulants in patients with atrial fibrillation. A consensus document of the Italian Federation of Thrombosis Centers (FCSA).

Journal: Thrombosis and haemostasis 20111101

Title: Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non-valvular atrial fibrillation from the RE-LY trial.

Journal: Journal of thrombosis and haemostasis : JTH 20111101

Title: A new landscape for stroke prevention in atrial fibrillation: focus on new anticoagulants, antiarrhythmic drugs, and devices.

Journal: Stroke 20111101

Title: [New anticoagulants. Characteristics, monitoring and management of bleeding].

Journal: Medizinische Klinik, Intensivmedizin und Notfallmedizin 20111101

Title: Dabigatran after cardiac surgery: caution advised.

Journal: The Journal of thoracic and cardiovascular surgery 20111101

Title: A study of thromboprophylactic practices of Scottish orthopaedic surgeons in patients undergoing total hip replacements. Should practice change with new guidelines?

Journal: Scottish medical journal 20111101

Title: [Atrial fibrillation and cardiembolic stroke. Treatment and issue in acute phase].

Journal: Rinsho shinkeigaku = Clinical neurology 20111101

Title: [Expectation to and problems of thrombin inhibitor].

Journal: Rinsho shinkeigaku = Clinical neurology 20111101

Title: [Current status and future of anti-Xa inhibitors].

Journal: Rinsho shinkeigaku = Clinical neurology 20111101

Title: [New anticoagulants].

Journal: La Revue du praticien 20111101

Title: Anticoagulation with the oral direct thrombin inhibitor dabigatran does not enlarge hematoma volume in experimental intracerebral hemorrhage.

Journal: Circulation 20111011

Title: Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects.

Journal: Circulation 20111004

Title: Reversal of new oral anticoagulants.

Journal: Circulation 20111004

Title: Direct thrombin inhibitors.

Journal: British journal of clinical pharmacology 20111001

Title: Trousseau's syndrome in a patient with adenocarcinoma of unknown primary and therapy-resistant venous thrombosis treated with dabigatran and fondaparinux.

Journal: British journal of clinical pharmacology 20111001

Title: Pharmacologic strategies for the prevention of stroke in patients with atrial fibrillation.

Journal: Current treatment options in cardiovascular medicine 20111001

Title: Update on the management of atrial fibrillation: anticoagulation and medical therapy.

Journal: Current cardiology reports 20111001

Title: New anticoagulants: how to deal with treatment failure and bleeding complications.

Journal: British journal of clinical pharmacology 20111001

Title: Review of the randomized evaluation of long-term anticoagulation therapy (RE-LY) trial: warfarin versus dabigatran.

Journal: Current cardiology reports 20111001

Title: Anticoagulating obese patients in the modern era.

Journal: British journal of haematology 20111001

Title: Drug-induced exanthem following dabigatran.

Journal: The Annals of pharmacotherapy 20111001

Title: New and emerging anticoagulant therapy for atrial fibrillation and acute coronary syndrome.

Journal: Pharmacotherapy 20111001

Title: Novel oral anticoagulants for VTE prevention in orthopedic surgery: overview of phase 3 trials.

Journal: Orthopedics 20111001

Title: Dabigatran: will it change clinical practice?

Journal: Cleveland Clinic journal of medicine 20111001

Title: Dutch guideline on total hip prosthesis.

Journal: Acta orthopaedica 20111001

Title: Should dabigatran replace warfarin for stroke prevention in AF?

Journal: Drug and therapeutics bulletin 20111001

Title: Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood.

Journal: PLoS pathogens 20111001

Title: The new oral anticoagulants.

Journal: Clinical medicine (London, England) 20111001

Title: Apixaban for stroke prevention in atrial fibrillation: a review of the clinical trial evidence.

Journal: Hospital practice (1995) 20111001

Title: [New antithrombotic drugs for the treatment of venous thromboembolism].

Journal: Revue des maladies respiratoires 20111001

Title: [Interpretation of hemostatic and fibrinolytic markers].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20111001

Title: Persistent ductus arteriosus in a 72-year-old woman with paroxysmal atrial fibrillation and depression syndrome: a therapeutic and diagnostic problem.

Journal: Archives of medical science : AMS 20111001

Title: [Atrial fibrillation: what the GP needs to know].

Journal: MMW Fortschritte der Medizin 20110922

Title: [Modern risk assessment and stroke prevention in atrial fibrillation].

Journal: Praxis 20110921

Title: ACP Journal Club. Dabigatran led to less major bleeding than warfarin in younger but not older patients with atrial fibrillation.

Journal: Annals of internal medicine 20110920

Title: A new era for anticoagulation in atrial fibrillation.

Journal: The New England journal of medicine 20110915

Title: New options in anticoagulation for atrial fibrillation.

Journal: The New England journal of medicine 20110908

Title: Emerging options in the treatment of deep vein thrombosis and pulmonary embolism.

Journal: Blood reviews 20110901

Title: Dabigatran falsely elevates point of care international normalized ratio results.

Journal: The American journal of medicine 20110901

Title: Prevention of venous thromboembolism after major orthopedic surgery: indirect comparison of three new oral anticoagulants.

Journal: Journal of thrombosis and haemostasis : JTH 20110901

Title: Update on anti-coagulation in atrial fibrillation.

Journal: QJM : monthly journal of the Association of Physicians 20110901

Title: Dabigatran etexilate (Pradaxa) for the treatment of atrial fibrillation.

Journal: The Nurse practitioner 20110901

Title: [Thromboembolic prophylaxis 2011: is warfarin on the wane?].

Journal: Giornale italiano di cardiologia (2006) 20110901

Title: Update on dabigatran for stroke prevention in atrial fibrillation.

Journal: Connecticut medicine 20110901

Title: Dabigatran: a review of clinical and pharmacoeconomic evidence.

Journal: Critical pathways in cardiology 20110901

Title: Direct thrombin inhibitors for the treatment of venous thromboembolism: analysis of the Dabigatran versus Warfarin clinical trial.

Journal: Seminars in vascular surgery 20110901

Title: New antithrombotic drugs and European approval processes.

Journal: Lancet (London, England) 20110820

Title: Dabigatran-induced rash.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110815

Title: Pros and cons of dabigatran.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110815

Title: Dabigatran etexilate: A novel oral direct thrombin inhibitor.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110815

Title: [The new Anticoagulants - Relevant Facts for the GP].

Journal: Praxis 20110810

Title: ['Xa-tra-xa': opportunities and open questions about new anticoagulants].

Journal: Praxis 20110810

Title: Novel oral anticoagulants: focus on stroke prevention and treatment of venous thrombo-embolism.

Journal: European heart journal 20110801

Title: Incidence of chronic kidney disease in patients with atrial fibrillation and its relevance for prescribing new oral antithrombotic drugs.

Journal: Journal of thrombosis and haemostasis : JTH 20110801

Title: Clopidogrel hydrogen sulphate for atrial fibrillation.

Journal: Expert opinion on pharmacotherapy 20110801

Title: New anticoagulants for prevention of stroke in patients with atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20110801

Title: Role of emerging antithrombotic therapy in the prevention of cardioembolic complications in patients with atrial fibrillation.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110801

Title: [New concepts in the therapy of atrial fibrillation].

Journal: Deutsche medizinische Wochenschrift (1946) 20110801

Title: [Pharmacological and clinical profiles of the direct thrombin inhibitor dabigatran etexilate methane sulfate (Prazaxa(®)) ].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110801

Title: Hospital-based clinical implications of the novel oral anticoagulant, dabigatran etexilate, in daily practice.

Journal: Hospital practice (1995) 20110801

Title: Dabigatran for stroke prevention in all patients with atrial fibrillation?

Journal: Pharmacotherapy 20110801

Title: New oral anticoagulants for venous thromboembolism (VTE) prophylaxis.

Journal: The Medical journal of Malaysia 20110801

Title: Dabigatran in patients with nonvalvular atrial fibrillation.

Journal: Journal of the American College of Cardiology 20110726

Title: The use of dabigatran in elderly patients.

Journal: Archives of internal medicine 20110725

Title: New anticoagulant drugs among elderly patients is caution necessary?: Comment on 'The use of dabigatran in elderly patients'.

Journal: Archives of internal medicine 20110725

Title: Atrial fibrillation: outpatient presentation and management.

Journal: Circulation 20110705

Title: Novel oral anticoagulants in development: Dabigatran, Rivaroxaban, and Apixaban.

Journal: American journal of therapeutics 20110701

Title: S35972, a direct-acting thrombin inhibitor with high oral bioavailability and antithrombotic efficacy.

Journal: Journal of thrombosis and haemostasis : JTH 20110701

Title: Thrombolysis treatment for acute ischaemic stroke in a patient on treatment with dabigatran.

Journal: Thrombosis and haemostasis 20110701

Title: Frontiers of anticoagulation therapy for atrial fibrillation.

Journal: Journal of cardiology 20110701

Title: Prevention of cardioembolic stroke.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110701

Title: Potential inaccuracy of point-of-care INR in dabigatran-treated patients.

Journal: The Annals of pharmacotherapy 20110701

Title: Treatment of risk factors to prevent stroke.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110701

Title: Edoxaban: pharmacological principles, preclinical and early-phase clinical testing.

Journal: Future cardiology 20110701

Title: [New anticoagulants in the prevention and treatment of venous thromboembolism].

Journal: Orvosi hetilap 20110619

Title: Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer.

Journal: The Cochrane database of systematic reviews 20110615

Title: Cost-effectiveness of dabigatran for stroke prophylaxis in atrial fibrillation.

Journal: Circulation 20110607

Title: Atrial fibrillation and percutaneous coronary intervention: stroke, thrombosis, and bleeding.

Journal: Current treatment options in cardiovascular medicine 20110601

Title: Treating arrhythmias: an expert opinion.

Journal: Expert opinion on pharmacotherapy 20110601

Title: Effectiveness of dabigatran etexilate for thromboprophylaxis of mechanical heart valves.

Journal: The Journal of thoracic and cardiovascular surgery 20110601

Title: Dabigatran: an oral direct thrombin inhibitor for use in atrial fibrillation.

Journal: Advances in therapy 20110601

Title: Prevention of atrial fibrillation complications with antiarrhythmic drugs: still an unmet need in clinical practice.

Journal: Expert opinion on pharmacotherapy 20110601

Title: New drugs 2011 part 2.

Journal: Nursing 20110601

Title: A benefit-risk assessment of dabigatran in the prevention of venous thromboembolism in orthopaedic surgery.

Journal: Drug safety 20110601

Title: Atrial fibrillation: epidemiology, prognosis and therapy.

Journal: Minerva medica 20110601

Title: [New oral anticoagulants for treatment of venous thromboembolism].

Journal: Deutsche medizinische Wochenschrift (1946) 20110601

Title: Prophylaxis of venous thromboembolism: low molecular weight heparin compared to the selective anticoagulants rivaroxaban, dabigatran and fondaparinux.

Journal: International angiology : a journal of the International Union of Angiology 20110601

Title: What's new in stroke? The top 10 studies of 2009-2011: part II.

Journal: Polskie Archiwum Medycyny Wewnetrznej 20110601

Title: [Is the era from the end of warfarin?].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20110601

Title: Dabigatran: a new option for anticoagulation in atrial fibrillation and venous thromboembolism.

Journal: Critical pathways in cardiology 20110601

Title: What are the emerging therapeutic alternatives to warfarin in stroke patients? How would the results of RE-LY benefit Pakistanis?

Journal: JPMA. The Journal of the Pakistan Medical Association 20110601

Title: Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial.

Journal: Circulation 20110531

Title: Anticoagulant options--why the FDA approved a higher but not a lower dose of dabigatran.

Journal: The New England journal of medicine 20110512

Title: Update on pharmacologic approaches to prevent thromboembolism in atrial fibrillation: are thrombin and factor Xa inhibitors the ultimate answer?

Journal: Current vascular pharmacology 20110501

Title: Coagulation parameters in patients receiving dabigatran etexilate or rivaroxaban: two observational studies in patients undergoing total hip or total knee replacement.

Journal: Thrombosis research 20110501

Title: Laboratory assessment of new anticoagulants.

Journal: Clinical chemistry and laboratory medicine 20110501

Title: Antiinflammatory and antifibrotic effects of the oral direct thrombin inhibitor dabigatran etexilate in a murine model of interstitial lung disease.

Journal: Arthritis and rheumatism 20110501

Title: Preclinical discovery of apixaban, a direct and orally bioavailable factor Xa inhibitor.

Journal: Journal of thrombosis and thrombolysis 20110501

Title: Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation: a Canadian payer perspective.

Journal: Thrombosis and haemostasis 20110501

Title: Risk-benefit ratio assessment for stroke prevention in intermediate risk atrial fibrillation patients: will TEE-based aspirin treatment fill the gap?

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110501

Title: Dabigatran etexilate: a novel oral thrombin inhibitor for thromboembolic disease.

Journal: The Annals of pharmacotherapy 20110501

Title: Feasibility of TEE-guided stroke risk assessment in atrial fibrillation-background, aims, design and baseline data of the TIARA pilot study.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20110501

Title: Spotlight on dabigatran etexilate in the prevention of stroke and systemic embolism in patients with atrial fibrillation.

Journal: Drugs & aging 20110501

Title: [New oral anticoagulant drugs: dabigatran, rivaroxaban and apixaban. Present and future].

Journal: Medecine sciences : M/S 20110501

Title: [The new anticoagulants].

Journal: Harefuah 20110501

Title: Ask the doctor. For several years, I have been taking warfarin because of atrial fibrillation. I recently suffered several nosebleeds, which took two days to control. The trauma of those episodes makes me want to swear off warfarin, but I am not sure what other options I have.

Journal: Harvard health letter 20110501

Title: Dabigatran compared with warfarin for stroke prevention in atrial fibrillation.

Journal: Annals of internal medicine 20110419

Title: Dabigatran compared with warfarin for stroke prevention in atrial fibrillation.

Journal: Annals of internal medicine 20110419

Title: [Current and future therapies for prophylaxis of thromboembolism in atrial fibrillation].

Journal: MMW Fortschritte der Medizin 20110414

Title: Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa.

Journal: Blood 20110407

Title: Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II*). A randomised, double-blind, non-inferiority trial.

Journal: Thrombosis and haemostasis 20110401

Title: What do the RE-LY, AVERROES and ROCKET-AF trials tell us for stroke prevention in atrial fibrillation?

Journal: Thrombosis and haemostasis 20110401

Title: Stroke prevention in atrial fibrillation: atrial appendage closure.

Journal: Current cardiology reports 20110401

Title: New oral anticoagulants.

Journal: Journal of thrombosis and thrombolysis 20110401

Title: Some considerations about the hypercoagulable states and their treatments.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20110401

Title: New insights on the role of direct thrombin inhibitors for the prevention of venous thromboembolism after major orthopaedic surgery.

Journal: Thrombosis and haemostasis 20110401

Title: Drug and dietary interactions of warfarin and novel oral anticoagulants: an update.

Journal: Journal of thrombosis and thrombolysis 20110401

Title: [Warfarin or dabigatran in patients with atrial fibrillation. RE-LY study (Randomized Evaluation of Long-term anticoagulation therapY)].

Journal: Der Internist 20110401

Title: [Dabigatran, a new oral anticoagulant].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20110401

Title: Place of dabigatran in contemporary pharmacotherapy.

Journal: Pharmacotherapy 20110401

Title: Preventing postsurgical venous thromboembolism: pharmacological approaches.

Journal: Seminars in thrombosis and hemostasis 20110401

Title: Differences between the varicella vaccines; using dabigatran.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20110401

Title: 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on Dabigatran): a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines.

Journal: Circulation 20110315

Title: 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran): a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines.

Journal: Journal of the American College of Cardiology 20110315

Title: Italian intersociety consensus statement on antithrombotic prophylaxis in hip and knee replacement and in femoral neck fracture surgery.

Journal: Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20110301

Title: Changing anticoagulant paradigms for atrial fibrillation: dabigatran, apixaban and rivaroxaban.

Journal: Expert opinion on pharmacotherapy 20110301

Title: Old and new anticoagulant drugs: a minireview.

Journal: Annals of medicine 20110301

Title: 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran). A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Journal: Heart rhythm 20110301

Title: [Should dabigatran or vitamin K antagonists be used in prevention of stroke in patients with atrial fibrillation?].

Journal: Revista clinica espanola 20110301

Title: Dabigatran as anticoagulant therapy for atrial fibrillation. Which patients should receive it, which patients may not need it, and other practical aspects of patient management.

Journal: Polskie Archiwum Medycyny Wewnetrznej 20110301

Title: Dabigatran for stroke prevention in atrial fibrillation: the RE-LY trial.

Journal: Expert review of cardiovascular therapy 20110301

Title: Atrial fibrillation: RE-LY: dabigatran in cardioversion.

Journal: Nature reviews. Cardiology 20110301

Title: Idiopathic venous thromboembolism and thrombophilia.

Journal: Journal of medicine and life 20110215

Title: Anticoagulation: improve care quality or use new alternatives?

Journal: Lancet (London, England) 20110205

Title: [General internal medicine: important articles about ambulatory care published in 2010].

Journal: Revue medicale suisse 20110202

Title: Dabigatran etexilate versus warfarin as the oral anticoagulant of choice? A review of clinical data.

Journal: Pharmacology & therapeutics 20110201

Title: Stroke prevention in the high-risk atrial fibrillation patient: Medical management.

Journal: Current cardiology reports 20110201

Title: Effects of the oral, direct thrombin inhibitor dabigatran on five common coagulation assays.

Journal: Thrombosis and haemostasis 20110201

Title: Dabigatran and rivaroxaban for prevention of venous thromboembolism--systematic review and adjusted indirect comparison.

Journal: Journal of clinical pharmacy and therapeutics 20110201

Title: [Direct inhibitors of thrombin, hirudin, bivalirudin, and dabigatran etexilate].

Journal: Journal des maladies vasculaires 20110201

Title: Novel anticoagulants: a discussion of clinical use in the treatment and prevention of venous thromboembolism.

Journal: Phlebology 20110201

Title: Atrial fibrillation in 2010: advances in treatment and management.

Journal: Nature reviews. Cardiology 20110201

Title: Association of warfarin use with valvular and vascular calcification: a review.

Journal: Clinical cardiology 20110201

Title: Old and new anticoagulants.

Journal: Hamostaseologie 20110201

Title: New anticoagulants: pharmacology and clinical studies.

Journal: Wiener medizinische Wochenschrift (1946) 20110201

Title: Direct thrombin and factor Xa inhibitors in children: a quest for new anticoagulants for children.

Journal: Wiener medizinische Wochenschrift (1946) 20110201

Title: Next generation anticoagulants may push warfarin to the wayside.

Journal: Managed care (Langhorne, Pa.) 20110201

Title: Dabigatran etexilate: a possible replacement for heparinoids and vitamin K antagonists?

Journal: Hospital practice (1995) 20110201

Title: New drug offers warfarin alternative for atrial fibrillation. An immediate switch is right for some people, but not necessary for all.

Journal: Harvard heart letter : from Harvard Medical School 20110201

Title: New oral anticoagulants and outpatient prophylaxis of venous thromboembolism.

Journal: The American journal of managed care 20110201

Title: Characteristics of novel anticoagulants and potential economic implications.

Journal: The American journal of managed care 20110201

Title: Is it time to abandon warfarin and embrace oral direct thrombin inhibitors to prevent stroke in patients with atrial fibrillation?

Journal: Neurosurgery 20110201

Title: Dabigatran versus warfarin in patients with atrial fibrillation: an analysis of patients undergoing cardioversion.

Journal: Circulation 20110118

Title: ACP Journal Club. Local INR control had some effect on the benefits of dabigatran over warfarin for major bleeding in atrial fibrillation.

Journal: Annals of internal medicine 20110118

Title: New oral anticoagulants for thromboprophylaxis in patients having hip or knee arthroplasty.

Journal: BMJ (Clinical research ed.) 20110118

Title: Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation.

Journal: Annals of internal medicine 20110104

Title: Newer anticoagulants as an alternate to warfarin in atrial fibrillation: a changing paradigm.

Journal: American journal of therapeutics 20110101

Title: Novel anticoagulants: new evidence for emerging drugs and their potential application in major lower limb surgery.

Journal: Current vascular pharmacology 20110101

Title: Moving the tipping point: the decision to anticoagulate patients with atrial fibrillation.

Journal: Circulation. Cardiovascular quality and outcomes 20110101

Title: Factor Xa and thrombin as targets for new oral anticoagulants.

Journal: Thrombosis research 20110101

Title: Novel oral factor Xa and thrombin inhibitors in the management of thromboembolism.

Journal: Annual review of medicine 20110101

Title: New drugs: dabigatran etexilate mesylate, fingolimod hydrochloride, and ulipristal acetate.

Journal: Journal of the American Pharmacists Association : JAPhA 20110101

Title: The difference between Tdap and DTaP; dabigatran versus warfarin.

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20110101

Title: Dabigatran etexilate: a review of its use in the prevention of stroke and systemic embolism in patients with atrial fibrillation.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110101

Title: Stroke. Dabigatran and stroke prevention.

Journal: Nature reviews. Neurology 20110101

Title: [New antithrombotics for atrial fibrillation].

Journal: Nederlands tijdschrift voor geneeskunde 20110101

Title: New oral anticoagulants: should they replace heparins and warfarin?

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20110101

Title: Electrophysiology and adult congenital heart disease: advances and options.

Journal: Progress in cardiovascular diseases 20110101

Title: South African experts comment on FDA approval of dabigatran in atrial fibrillation.

Journal: Cardiovascular journal of Africa 20110101

Title: Comparing the 2010 North American and European atrial fibrillation guidelines.

Journal: The Canadian journal of cardiology 20110101

Title: Canadian Cardiovascular Society atrial fibrillation guidelines 2010: prevention of stroke and systemic thromboembolism in atrial fibrillation and flutter.

Journal: The Canadian journal of cardiology 20110101

Title: An Observational, Prospective Survey Assessing the Control of Atrial Fibrillation in Asia Pacific: Rationale and Design of the RecordAF-AP Registry.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: An indirect comparison, via enoxaparin, of rivaroxaban with dabigatran in the prevention of venous thromboembolism after hip or knee replacement.

Journal: Journal of medical economics 20110101

Title: Cost of AF Ablation: Where Do We Stand?

Journal: Cardiology research and practice 20110101

Title: Efficacy and safety of dabigatran vs. warfarin in patients with atrial fibrillation--sub-analysis in Japanese population in RE-LY trial.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Differentiation of parenteral anticoagulants in the prevention and treatment of venous thromboembolism.

Journal: Thrombosis journal 20110101

Title: A network-based multi-target computational estimation scheme for anticoagulant activities of compounds.

Journal: PloS one 20110101

Title: Cardiac crossroads: deciding between mechanical or bioprosthetic heart valve replacement.

Journal: Patient preference and adherence 20110101

Title: [Perioperative venous thromboembolism prophylaxis].

Journal: La Revue du praticien 20110101

Title: Heparin-induced thrombocytopenia in the ICU: an overview.

Journal: Critical care (London, England) 20110101

Title: Dabigatran etexilate: the first oral anticoagulant available in the United States since warfarin.

Journal: Cardiology in review 20110101

Title: The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation.

Journal: Vascular health and risk management 20110101

Title: Evaluation of the efficacy and safety of rivaroxaban using a computer model for blood coagulation.

Journal: PloS one 20110101

Title: New oral anticoagulants for venous thromboembolism prophylaxis in orthopaedic surgery.

Journal: Instructional course lectures 20110101

Title: Stroke prevention in atrial fibrillation.

Journal: Cardiovascular journal of Africa 20110101

Title: Stroke risk reduction: focus of the new ESC guidelines.

Journal: Cardiovascular journal of Africa 20110101

Title: Left Atrial Appendage Closure in Atrial Fibrillation: A World without Anticoagulation?

Journal: Cardiology research and practice 20110101

Title: Pharmacological management of atrial fibrillation: one, none, one hundred thousand.

Journal: Cardiology research and practice 20110101

Title: Study protocol: the DESPATCH study: delivering stroke prevention for patients with atrial fibrillation - a cluster randomised controlled trial in primary healthcare.

Journal: Implementation science : IS 20110101

Title: [Drug prevention of pulmonary embolism in orthopedic practice: traditional and novel approaches].

Journal: Kardiologiia 20110101

Title: Antithrombotic therapy in atrial fibrillation: evaluation and positioning of new oral anticoagulant agents.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: Performance of stroke risk scores in older people with atrial fibrillation not taking warfarin: comparative cohort study from BAFTA trial.

Journal: BMJ (Clinical research ed.) 20110101

Title: Re-LY trial: new sub-analyses highlight stroke reduction in all types of non-valvular atrial fibrillation.

Journal: Cardiovascular journal of Africa 20110101

Title: Controlled release of chitosan/heparin nanoparticle-delivered VEGF enhances regeneration of decellularized tissue-engineered scaffolds.

Journal: International journal of nanomedicine 20110101

Title: Battle of oral anticoagulants in the field of atrial fibrillation scrutinized from a clinical practice (the real world) perspective.

Journal: Thrombosis journal 20110101

Title: Antithrombotic medication for cardioembolic stroke prevention.

Journal: Stroke research and treatment 20110101

Title: Stroke prevention in nonvalvular atrial fibrillation.

Journal: Texas Heart Institute journal 20110101

Title: Comparison of pharmacist managed anticoagulation with usual medical care in a family medicine clinic.

Journal: BMC family practice 20110101

Title: Management of patients with atrial fibrillation: specific considerations for the old age.

Journal: Cardiology research and practice 20110101

Title: [Atrial fibrillation: novel possibilities of anticoagulant therapy in patients subjected to cardioversion].

Journal: Kardiologiia 20110101

Title: Evaluation of marine brown algae and sponges from Brazil as anticoagulant and antiplatelet products.

Journal: Marine drugs 20110101

Title: Drug name alert: potential for confusion between pradax and plavix.

Journal: Dynamics (Pembroke, Ont.) 20110101

Title: Prophylaxis for deep vein thrombosis and pulmonary embolism in the surgical patient.

Journal: Advances in surgery 20110101

Title: [The new oral anticoagulants in surgery].

Journal: Revista medica del Instituto Mexicano del Seguro Social 20110101

Title: Emerging therapies for acute coronary syndromes.

Journal: Frontiers in pharmacology 20110101

Title: Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration.

Journal: PloS one 20110101

Title: Dabigatran etexilate versus warfarin in management of non-valvular atrial fibrillation in UK context: quantitative benefit-harm and economic analyses.

Journal: BMJ (Clinical research ed.) 20110101

Title: Cost of dabigatran for atrial fibrillation.

Journal: BMJ (Clinical research ed.) 20110101

Title: Crystal structure of thrombin in complex with S-variegin: insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors.

Journal: PloS one 20110101

Title: Dabigatran.

Journal: AJNR. American journal of neuroradiology 20110101

Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Venous thromboembolism: classification, risk factors, diagnosis, and management.

Journal: ISRN hematology 20110101

Title: [Self-management in anticoagulant therapy--implications for the future?].

Journal: Nederlands tijdschrift voor geneeskunde 20110101

Title: Preoperative versus postoperative initiation of thromboprophylaxis following major orthopedic surgery: safety and efficacy of postoperative administration supported by recent trials of new oral anticoagulants.

Journal: Thrombosis journal 20110101

Title: Wound problems following hip arthroplasty before and after the introduction of a direct thrombin inhibitor for thromboprophylaxis.

Journal: Hip international : the journal of clinical and experimental research on hip pathology and therapy 20110101

Title: [Dabigatran eteksilat new anticoagulant for the prevention of stroke in patients with atrial fibrillation without valvular lesions].

Journal: Kardiologiia 20110101

Title: Anticoagulants and the propagation phase of thrombin generation.

Journal: PloS one 20110101

Title: Fatal intracerebral hemorrhage associated with administration of recombinant tissue plasminogen activator in a stroke patient on treatment with dabigatran.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20110101

Title: Fibrinolytic treatment of acute ischemic stroke for patients on new oral anticoagulant drugs.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20110101

Title: Gene-drug interaction in stroke.

Journal: Stroke research and treatment 20110101

Title: Oral fondaparinux: use of lipid nanocapsules as nanocarriers and in vivo pharmacokinetic study.

Journal: International journal of nanomedicine 20110101

Title: Pharmacological basis and clinical evidence of dabigatran therapy.

Journal: Journal of hematology & oncology 20110101

Title: The case for an elderly targeted stroke management.

Journal: Frontiers in neurology 20110101

Title: Oral thromboprophylaxis following total hip or knee replacement: review and multicentre experience with dabigatran etexilate.

Journal: The open orthopaedics journal 20110101

Title: Deep vein thrombosis: a clinical review.

Journal: Journal of blood medicine 20110101

Title: Dabigatran emerges as safe and effective warfarin alternative. The recently approved drug is more expensive, but appears to be more predictable.

Journal: Heart advisor 20110101

Title: Novel anticoagulants for stroke prevention in atrial fibrillation: current clinical evidence and future developments.

Journal: Journal of the American College of Cardiology 20101214

Title: Stroke in atrial fibrillation--hope on the horizon?

Journal: Journal of the Royal Society, Interface 20101206

Title: [New oral anticoagulants: better than vitamin K antagonists?].

Journal: Der Internist 20101201

Title: Treatments for stroke prevention in atrial fibrillation: a network meta-analysis and indirect comparisons versus dabigatran etexilate.

Journal: Thrombosis and haemostasis 20101201

Title: First oral warfarin alternative approved in the US.

Journal: Nature reviews. Drug discovery 20101201

Title: New synthetic antithrombotic agents for venous thromboembolism: pentasaccharides, direct thrombin inhibitors, direct Xa inhibitors.

Journal: Clinics in chest medicine 20101201

Title: Peri-operative management of anti-platelet agents and anti-thrombotic agents in geriatric patients undergoing semi-urgent hip fracture surgery.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20101201

Title: Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial.

Journal: The Lancet. Neurology 20101201

Title: Dabigatran in atrial fibrillation: balancing secondary stroke prevention against bleeding risk.

Journal: The Lancet. Neurology 20101201

Title: [Dabigatran induced exanthema].

Journal: Revista clinica espanola 20101201

Title: Warfarin or not.

Journal: The journal of the Royal College of Physicians of Edinburgh 20101201

Title: Advances in the treatment of atrial fibrillation.

Journal: Minerva cardioangiologica 20101201

Title: [Antithrombotic and anticoagulation therapy after stroke and transient ischemic attacks].

Journal: Der Nervenarzt 20101201

Title: Recurrent venous thrombosis despite 'optimal anticoagulation therapy' for antiphospholipid syndrome--could new oral anticoagulants solve the problem?

Journal: Acta clinica Croatica 20101201

Title: Dabigatran and warfarin in vitamin K antagonist-naive and -experienced cohorts with atrial fibrillation.

Journal: Circulation 20101130

Title: Use of dabigatran etexilate to reduce breast cancer progression.

Journal: Cancer biology & therapy 20101115

Title: Dabigatran etexilate (Pradaxa)--a new oral anticoagulant.

Journal: The Medical letter on drugs and therapeutics 20101115

Title: Dabigatran: the anticoagulant we have long expected?

Journal: Recent patents on cardiovascular drug discovery 20101101

Title: Double-blind, placebo-controlled Phase II studies of the protease-activated receptor 1 antagonist E5555 (atopaxar) in Japanese patients with acute coronary syndrome or high-risk coronary artery disease.

Journal: European heart journal 20101101

Title: Enoxaparin versus dabigatran or rivaroxaban for thromboprophylaxis after hip or knee arthroplasty: Results of separate pooled analyses of phase III multicenter randomized trials.

Journal: Circulation. Cardiovascular quality and outcomes 20101101

Title: Stroke risk and antithrombotic strategies in atrial fibrillation.

Journal: Stroke 20101101

Title: Blood transfusion and the anaesthetist: management of massive haemorrhage.

Journal: Anaesthesia 20101101

Title: Intracerebral hemorrhage: Pick your poison.

Journal: Cleveland Clinic journal of medicine 20101101

Title: What's new in treating older adults?

Journal: Cleveland Clinic journal of medicine 20101101

Title: Korean guidelines for the prevention of venous thromboembolism.

Journal: Journal of Korean medical science 20101101

Title: [Novel anticoagulants for stroke prevention in atrial fibrillation].

Journal: Deutsche medizinische Wochenschrift (1946) 20101101

Title: [Recommendations for the administration of conventional and new antithrombotic agents from the perspective of anesthesiology].

Journal: Der Unfallchirurg 20101101

Title: [Two new anticoagulants available in 2010--Dabigatran Etexilate and Rivaroxaban: expected progresses--raised problems].

Journal: Annales pharmaceutiques francaises 20101101

Title: [Report from International Stroke Conference 2010, San Antonio, USA].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20101101

Title: New options for stroke prevention in atrial fibrillation.

Journal: The American journal of managed care 20101101

Title: Dabigatran v warfarin. Compare with higher standard.

Journal: BMJ (Clinical research ed.) 20101026

Title: New approaches to atrial fibrillation management: treat the patient, not the ECG.

Journal: Cardiovascular therapeutics 20101001

Title: The influence of direct thrombin inhibitors on the formation of platelet-leukocyte aggregates and tissue factor expression.

Journal: Thrombosis research 20101001

Title: Dabigatran offers the simplest solution for thromboprophylaxis after orthopaedic surgery in patients allergic to low-molecular-weight heparins.

Journal: British journal of haematology 20101001

Title: New antithrombotics for atrial fibrillation.

Journal: Cardiovascular therapeutics 20101001

Title: Dabigatran: an oral novel potent reversible nonpeptide inhibitor of thrombin.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20101001

Title: Atrial fibrillation and dabigatran: has the time come to use new anticoagulants?

Journal: Cardiovascular therapeutics 20101001

Title: Emerging antithrombotic agents: what does the intensivist need to know?

Journal: Current opinion in critical care 20101001

Title: The evolving field of stroke prevention in patients with atrial fibrillation.

Journal: Stroke 20101001

Title: [Secondary stroke prevention - an update].

Journal: Fortschritte der Neurologie-Psychiatrie 20101001

Title: Prevention of cardioembolic stroke in patients with atrial fibrillation.

Journal: Expert review of cardiovascular therapy 20101001

Title: Dabigatran for stroke prevention in atrial fibrillation: from RE-LY to daily clinical practice.

Journal: Acta cardiologica 20101001

Title: [Medication of the month. Dabigatran etixilate (Pradaxa): an oral anticoagulant acting as a direct selective inhibitor of thrombin].

Journal: Revue medicale de Liege 20101001

Title: A new anticoagulant for a new era: review of recent data on dabigatran etexilate.

Journal: Clinical advances in hematology & oncology : H&O 20101001

Title: Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial.

Journal: Lancet (London, England) 20100918

Title: Quality of anticoagulation control in atrial fibrillation.

Journal: Lancet (London, England) 20100918

Title: [Oral prevention of thromboembolism with rivaroxaban and dabigatran: are the newly approved drugs innovations in orthopaedic and trauma surgery? ].

Journal: Zeitschrift fur Orthopadie und Unfallchirurgie 20100901

Title: Dabigatran versus enoxaparin for prevention of venous thromboembolism after hip or knee arthroplasty: a pooled analysis of three trials.

Journal: Thrombosis research 20100901

Title: Pooled analysis of trials may, in the presence of heterogeneity inadvertently lead to fragile conclusions due to the importance of clinically relevant variables being either hidden or lost when the findings are pooled.

Journal: Thrombosis research 20100901

Title: Dabigatran acylglucuronide, the major human metabolite of dabigatran: in vitro formation, stability, and pharmacological activity.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20100901

Title: Does warfarin for stroke thromboprophylaxis protect against MI in atrial fibrillation patients?

Journal: The American journal of medicine 20100901

Title: In vitro comparison of dabigatran, unfractionated heparin, and low-molecular-weight heparin in preventing thrombus formation on mechanical heart valves.

Journal: Thrombosis research 20100901

Title: [Advances in the prevention of cerebral ischaemia due to atrial fibrillation].

Journal: Neurologia (Barcelona, Spain) 20100901

Title: Warfarin: is the end nigh? Please?

Journal: The journal of the Royal College of Physicians of Edinburgh 20100901

Title: The impact of new and emerging clinical data on treatment strategies for atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20100801

Title: When a virtue becomes a problem. The new oral anticoagulants.

Journal: Journal of thrombosis and haemostasis : JTH 20100801

Title: Apixaban, a direct factor Xa inhibitor, inhibits tissue-factor induced human platelet aggregation in vitro: comparison with direct inhibitors of factor VIIa, XIa and thrombin.

Journal: Thrombosis and haemostasis 20100801

Title: Treatment of thromboembolism in cancer patients.

Journal: Expert opinion on pharmacotherapy 20100801

Title: Dabigatran may not be an effective anticoagulant for haemodialysis.

Journal: Nephrology (Carlton, Vic.) 20100801

Title: Prevention of stroke in patients with atrial fibrillation: the role of new antiarrhythmic and antithrombotic drugs.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20100801

Title: Antithrombotic therapy in cardiac embolism.

Journal: Current cardiology reviews 20100801

Title: New oral anticoagulant drugs in cardiovascular disease.

Journal: Thrombosis and haemostasis 20100701

Title: Clot prevention--common questions about medications.

Journal: Australian family physician 20100701

Title: Use of dabigatran versus warfarin for patients with atrial fibrillation.

Journal: Postgraduate medicine 20100701

Title: Thrombin-induced CCN2 expression as a target for anti-fibrotic therapy in scleroderma.

Journal: Journal of cell communication and signaling 20100601

Title: Does dabigatran improve stroke prevention in atrial fibrillation? A rebuttal.

Journal: Journal of thrombosis and haemostasis : JTH 20100601

Title: [A new deal with new anticoagulants?].

Journal: Journal des maladies vasculaires 20100601

Title: Will direct thrombin inhibition change the boundaries of oral anti-coagulation?

Journal: QJM : monthly journal of the Association of Physicians 20100601

Title: Old versus new anticoagulants: focus on pharmacology.

Journal: Recent patents on cardiovascular drug discovery 20100601

Title: Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity.

Journal: Thrombosis and haemostasis 20100601

Title: Anesthetic concerns for patients with coagulopathy.

Journal: Current opinion in anaesthesiology 20100601

Title: Dabigatran challenges warfarin's superiority for stroke prevention in atrial fibrillation.

Journal: Stroke 20100601

Title: Dabigatran etexilate, a new oral direct thrombin inhibitor, for stroke prevention in patients with atrial fibrillation.

Journal: Expert opinion on pharmacotherapy 20100601

Title: Update on antithrombotic therapy for stroke prevention in atrial fibrillation.

Journal: Current treatment options in cardiovascular medicine 20100601

Title: Review of an Article: Dabigatran versus warfarin in the treatment of acute venous thromboembolism (2009). Schulman S, Kearon C, Kakkar A, et al., N Engl J Med 361;2342-2352.

Journal: Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing 20100601

Title: Dabigatran etexilate: advances in anticoagulation therapy.

Journal: Expert review of cardiovascular therapy 20100601

Title: Boehringer launches first direct thrombin inhibitor: dabigatran (Pradaxa).

Journal: Cardiovascular journal of Africa 20100601

Title: Drug and dietary interactions of the new and emerging oral anticoagulants.

Journal: International journal of clinical practice 20100601

Title: Thrombi of different pathologies: implications for diagnosis and treatment.

Journal: Current treatment options in cardiovascular medicine 20100601

Title: Novel oral anticoagulants. Part II: direct thrombin inhibitors.

Journal: Expert review of hematology 20100601

Title: [New oral anticoagulants: prospects].

Journal: La Revue du praticien 20100520

Title: Update in hematology and oncology.

Journal: Annals of internal medicine 20100518

Title: Emerging anticoagulants for venous thromboembolism prevention.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100515

Title: New anticoagulants for prevention and treatment of venous thromboembolism.

Journal: Current vascular pharmacology 20100501

Title: Rivaroxaban and dabigatran etexilate: two new oral anticoagulants for extended postoperative prevention of venous thromboembolism after elective total hip arthroplasty.

Journal: Archives of orthopaedic and trauma surgery 20100501

Title: New and emerging antiarrhythmic and anticoagulant agents for atrial fibrillation.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100501

Title: Dabigatran was noninferior to warfarin for preventing recurrent venous thromboembolism.

Journal: Annals of internal medicine 20100420

Title: Direct thrombin inhibitors versus vitamin K antagonists or low molecular weight heparins for prevention of venous thromboembolism following total hip or knee replacement.

Journal: The Cochrane database of systematic reviews 20100414

Title: Primary prevention of venous thromboembolism in medical and surgical oncology patients.

Journal: British journal of cancer 20100413

Title: Dabigatran etexilate: a new thrombin inhibitor.

Journal: The Medical journal of Australia 20100405

Title: Dabigatran enhances clot susceptibility to fibrinolysis by mechanisms dependent on and independent of thrombin-activatable fibrinolysis inhibitor.

Journal: Journal of thrombosis and haemostasis : JTH 20100401

Title: Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study.

Journal: Clinical pharmacokinetics 20100401

Title: Insights from the dabigatran versus warfarin trial in patients with venous thromboembolism (the RE-COVER trial).

Journal: Expert opinion on pharmacotherapy 20100401

Title: Rivaroxaban vs dabigatran for thromboprophylaxis after joint-replacement surgery: exploratory indirect comparison based on meta-analysis of pivotal clinical trials.

Journal: Croatian medical journal 20100401

Title: Dabigatran: ready for prime time?

Journal: Polskie Archiwum Medycyny Wewnetrznej 20100401

Title: Potential of new anticoagulants in patients with cancer.

Journal: Thrombosis research 20100401

Title: Novel oral anticoagulants for prophylaxis and treatment of venous thromboembolism: part I (Factor Xa inhibitors).

Journal: Expert review of hematology 20100401

Title: Dabigatran versus warfarin for venous thromboembolism.

Journal: The New England journal of medicine 20100318

Title: Dabigatran versus warfarin for venous thromboembolism.

Journal: The New England journal of medicine 20100318

Title: Insights from the dabigatran versus warfarin in patients with atrial fibrillation (RE-LY) trial.

Journal: Expert opinion on pharmacotherapy 20100301

Title: Comparative efficacy and safety of the novel oral anticoagulants dabigatran, rivaroxaban and apixaban in preclinical and clinical development.

Journal: Thrombosis and haemostasis 20100301

Title: DVT: a new era in anticoagulant therapy.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20100301

Title: Where will the next generation of stroke treatments come from?

Journal: PLoS medicine 20100301

Title: [Preventing stroke by treating atrial fibrillation--new hope with dronedarone and dabigatran?].

Journal: Deutsche medizinische Wochenschrift (1946) 20100301

Title: [Pulmonary circulation: contributions of the year 2009].

Journal: Archivos de bronconeumologia 20100301

Title: Recent advances in the management of venous thromboembolism.

Journal: The Korean journal of hematology 20100301

Title: New oral anticoagulants: a practical guide for clinicians.

Journal: Journal of thrombosis and thrombolysis 20100201

Title: Replacing aspirin and warfarin for secondary stroke prevention: is it worth the costs?

Journal: Current opinion in neurology 20100201

Title: Economic evaluation of dabigatran etexilate for the prevention of venous thromboembolism in patients aged over 75 years or with moderate renal impairment undergoing total knee or hip replacement.

Journal: Thrombosis and haemostasis 20100201

Title: [Dabigatran: a new therapeutic option for therapy and prophylaxis of thromboembolic diseases?].

Journal: Deutsche medizinische Wochenschrift (1946) 20100201

Title: [Current state and perspectives of pharmacological and non-pharmacological treatment of atrial fibrillation: overview].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100201

Title: The ultimate anticoagulants?

Journal: Cardiovascular journal of Africa 20100201

Title: [Update on new antithrombotic treatments].

Journal: Revue medicale suisse 20100120

Title: The new oral anticoagulants.

Journal: Blood 20100107

Title: Atrial fibrillation: A promising new anticoagulant for stroke prevention.

Journal: Nature reviews. Cardiology 20100101

Title: The potential benefits of low-molecular-weight heparins in cancer patients.

Journal: Journal of hematology & oncology 20100101

Title: Modern role for clopidogrel in management of atrial fibrillation and stroke reduction.

Journal: Vascular health and risk management 20100101

Title: [Dabigatran in the treatment of a morbidly obese patient with recurring venous thrombosis].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101

Title: Current issues in patient adherence and persistence: focus on anticoagulants for the treatment and prevention of thromboembolism.

Journal: Patient preference and adherence 20100101

Title: New oral anticoagulants in development: potential for improved safety profiles.

Journal: Reviews in neurological diseases 20100101

Title: [Dabigatran versus warfarin in the treatment of acute venous thromboembolism. Results of the RE-COVER study].

Journal: Kardiologiia 20100101

Title: Forecasting drug utilization and expenditure in a metropolitan health region.

Journal: BMC health services research 20100101

Title: New options with dabigatran etexilate in anticoagulant therapy.

Journal: Vascular health and risk management 20100101

Title: New anticoagulants for the prevention of venous thromboembolism.

Journal: Drug design, development and therapy 20100101

Title: Deep vein thrombosis and pulmonary embolism - Prevention, management, and anaesthetic considerations.

Journal: Indian journal of anaesthesia 20100101

Title: [Cost-effectiveness analysis of methods for thromboprophylaxis after orthopedic surgery].

Journal: Khirurgiia 20100101

Title: Novel anticoagulant therapy: principle and practice.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Electrocardiographic abnormalities of takotsubo cardiomyopathy in a patient with paced ventricular rhythm.

Journal: Cardiology research and practice 20100101

Title: Dabigatran and acute stroke thrombolysis.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20100101

Title: Dabigatran and stroke thrombolysis.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20100101

Title: Thrombin-activatable fibrinolysis inhibitor (TAFI) deficient mice are susceptible to intracerebral thrombosis and ischemic stroke.

Journal: PloS one 20100101

Title: [Anticoagulant therapy in cardiology: yesterday, today, tomorrow].

Journal: Kardiologiia 20100101

Title: Prevention strategies for cardioembolic stroke: present and future perspectives.

Journal: The open neurology journal 20100101

Title: Cost effectiveness of venous thromboembolism pharmacological prophylaxis in total hip and knee replacement: a systematic review.

Journal: PharmacoEconomics 20100101

Title: Further issues with new oral anticoagulants.

Journal: Current pharmaceutical design 20100101

Title: New anticoagulants for the prevention of thromboembolism.

Journal: Current pharmaceutical design 20100101

Title: Pharmacologic properties of the new oral anticoagulants: a clinician-oriented review with a focus on perioperative management.

Journal: Current pharmaceutical design 20100101

Title: Managing bleeding complications in patients treated with the old and the new anticoagulants.

Journal: Current pharmaceutical design 20100101

Title: Intravenous thrombolysis with recombinant tissue plasminogen activator in a stroke patient treated with dabigatran.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20100101

Title: Post-operative thromboprophylaxis: new oral thrombin and factor X inhibitors and their place in clinical practice.

Journal: F1000 medicine reports 20100101

Title: Focus on 2010 ESC Congress: new ESC guidelines and data on dabigatran.

Journal: Cardiovascular journal of Africa 20100101

Title: Warfarin versus new agents: interpreting the data.

Journal: Hematology. American Society of Hematology. Education Program 20100101

Title: [Comparative effectiveness and safety of oral anticoagulants in treatment of acute thromboses of deep veins of the lower extremities].

Journal: Vestnik khirurgii imeni I. I. Grekova 20100101

Title: Newer antithrombotic drugs.

Journal: Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20100101

Title: Surveying the medical literature: five notable articles in general internal medicine from 2008 and 2009.

Journal: Open medicine : a peer-reviewed, independent, open-access journal 20100101

Title: Dabigatran is as effective as Warfarin in the treatment of acute venous thromboembolism - the RE-COVER study.

Journal: Maedica 20100101

Title: Simplifying thromboprophylaxis could improve outcomes in orthopaedic surgery.

Journal: Thrombosis 20100101

Title: New oral anticoagulants for thromboprophylaxis after elective total hip and knee arthroplasty.

Journal: Thrombosis 20100101

Title: Emerging antithrombotic agents for thromboprophylaxis, clinical potential and patient considerations.

Journal: Journal of blood medicine 20100101

Title: Dabigatran or rivaroxaban versus other anticoagulants for thromboprophylaxis after major orthopedic surgery: systematic review of comparative clinical-effectiveness and safety.

Journal: CADTH technology overviews 20100101

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20091231

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20091231

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20091231

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20091231

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20091231

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20091231

Title: Dabigatran versus warfarin in the treatment of acute venous thromboembolism.

Journal: The New England journal of medicine 20091210

Title: Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: a randomized dose-guiding, safety, and tolerability study of four doses of AZD0837 vs. vitamin K antagonists.

Journal: European heart journal 20091201

Title: [New oral anticoagulants. Consequences for perioperative coagulation diagnostics and therapy].

Journal: Der Anaesthesist 20091201

Title: Clinical trials update from the European Society of Cardiology Meeting 2009: AAA, RELY, PROTECT, ACTIVE-I, European CRT survey, German pre-SCD II registry, and MADIT-CRT.

Journal: European journal of heart failure 20091201

Title: At last, a RE-LYable alternative to warfarin for atrial fibrillation.

Journal: International journal of stroke : official journal of the International Stroke Society 20091201

Title: Oral anticoagulation with Factor Xa and thrombin inhibitors: Is there an alternative to warfarin?

Journal: Discovery medicine 20091201

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20091201

Title: The RE-LY study: Randomized Evaluation of Long-term anticoagulant therapY: dabigatran vs. warfarin.

Journal: European heart journal 20091101

Title: Dabigatran, a direct thrombin inhibitor, demonstrates antifibrotic effects on lung fibroblasts.

Journal: Arthritis and rheumatism 20091101

Title: Direct inhibitors of coagulation proteins - the end of the heparin and low-molecular-weight heparin era for anticoagulant therapy?

Journal: Thrombosis and haemostasis 20091101

Title: [New drug in atrial fibrillation--how does it function in regular health care?].

Journal: Lakartidningen 20091101

Title: [The results of the RE-lY study promise more effective, safer and easier prevention of embolic complications in patients with non-valvular atrial fibrillation].

Journal: Vnitrni lekarstvi 20091101

Title: [Pregnancy and venous thromboembolism. North-American and European guidelines. American College of Chest Physicians].

Journal: Journal des maladies vasculaires 20091101

Title: New agents for orthopaedic thromboprophylaxis: caution essential, but time will tell.

Journal: ANZ journal of surgery 20091101

Title: New anticoagulants and regional anesthesia.

Journal: Current opinion in anaesthesiology 20091001

Title: Anticoagulation with {blacktriangledown}dabigatran or{blacktriangledown}rivaroxaban.

Journal: Drug and therapeutics bulletin 20091001

Title: Rivaroxaban for the prevention of venous thromboembolism: a single technology appraisal.

Journal: Health technology assessment (Winchester, England) 20091001

Title: Dabigatran etexilate in venous thromboembolism.

Journal: Drugs of today (Barcelona, Spain : 1998) 20091001

Title: [Dabigatran is better than warfarin in patients with atrial fibrillation and stroke risk - Re-Ly studies].

Journal: Kardiologia polska 20091001

Title: [Is dabigatran the ideal drug against thrombosis? Commentary to RE-LY].

Journal: Kardiologia polska 20091001

Title: Can we rely on RE-LY?

Journal: The New England journal of medicine 20090917

Title: Dabigatran versus warfarin in patients with atrial fibrillation.

Journal: The New England journal of medicine 20090917

Title: [Stroke prevention in atrial fibrillation. Marcumar alternative in sight].

Journal: MMW Fortschritte der Medizin 20090917

Title: A logical approach to surgical thromboprophylaxis.

Journal: Current opinion in hematology 20090901

Title: Dabigatran etexilate for the prevention of venous thromboembolism in patients undergoing elective hip and knee surgery: a single technology appraisal.

Journal: Health technology assessment (Winchester, England) 20090901

Title: [Dabigatran (Pradaxa): efficacy and safety].

Journal: Annales francaises d'anesthesie et de reanimation 20090901

Title: [Anticoagulants drugs direct trombin inhibitors].

Journal: Annales francaises d'anesthesie et de reanimation 20090901

Title: [Perspectives in cardiology: evidence of efficacy in atrial fibrillation and hopes in acute coronary syndrome].

Journal: Annales francaises d'anesthesie et de reanimation 20090901

Title: [Dabigatran: clinical pharmacology].

Journal: Annales francaises d'anesthesie et de reanimation 20090901

Title: [New developments in antithrombotic care].

Journal: Revue medicale de Bruxelles 20090901

Title: Favorable therapeutic index of the direct factor Xa inhibitors, apixaban and rivaroxaban, compared with the thrombin inhibitor dabigatran in rabbits.

Journal: Journal of thrombosis and haemostasis : JTH 20090801

Title: Recent developments in the use of oral anticoagulants.

Journal: Expert opinion on pharmacotherapy 20090801

Title: What can ongoing clinical trials of anticoagulants demonstrate?

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090801

Title: Use of emerging oral anticoagulants in clinical practice: translating results from clinical trials to orthopedic and general surgical patient populations.

Journal: Annals of surgery 20090801

Title: [New anticoagulants for secondary haemostasis--anti IIa inhibitors].

Journal: Hamostaseologie 20090801

Title: New anticoagulants: focus on venous thromboembolism.

Journal: Current vascular pharmacology 20090701

Title: New anticoagulants for atrial fibrillation.

Journal: Seminars in thrombosis and hemostasis 20090701

Title: [New agents for the prevention of venous thromboembolism].

Journal: Der Internist 20090601

Title: Dabigatran: new drug. Continue to use heparin, a better-known option.

Journal: Prescrire international 20090601

Title: Rivaroxaban -- an oral, direct Factor Xa inhibitor: lessons from a broad clinical study programme.

Journal: European journal of haematology 20090501

Title: Rationale and design of RE-LY: randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran.

Journal: American heart journal 20090501

Title: [The new oral anticoagulant in the Netherlands].

Journal: Nederlands tijdschrift voor geneeskunde 20090418

Title: [New anticoagulants].

Journal: Deutsche medizinische Wochenschrift (1946) 20090401

Title: Should new oral anticoagulants replace low-molecular-weight heparin for thromboprophylaxis in orthopaedic surgery?

Journal: Archives of cardiovascular diseases 20090401

Title: The prevention of hospital-acquired venous thromboembolism in the United Kingdom.

Journal: British journal of haematology 20090301

Title: [Venous thromboembolism prophylaxis in orthopaedics and traumatology].

Journal: Vnitrni lekarstvi 20090301

Title: The novel anticoagulants: entering a new era.

Journal: Swiss medical weekly 20090207

Title: Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery.

Journal: The Journal of arthroplasty 20090101

Title: Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor xa inhibitors in development.

Journal: Clinical pharmacokinetics 20090101

Title: Dabigatran etexilate for prevention of venous thromboembolism.

Journal: Thrombosis and haemostasis 20090101

Title: Efficacy and safety of dabigatran etexilate for the prevention of venous thromboembolism following total hip or knee arthroplasty. A meta-analysis.

Journal: Thrombosis and haemostasis 20090101

Title: Coadministration of dabigatran etexilate and atorvastatin: assessment of potential impact on pharmacokinetics and pharmacodynamics.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101

Title: In the pipeline: new oral anticoagulants for the prevention of venous thromboembolism.

Journal: Orthopedics 20090101

Title: Economic evaluation of dabigatran etexilate for the prevention of venous thromboembolism after total knee and hip replacement surgery.

Journal: Clinical therapeutics 20090101

Title: New oral anticoagulants: not quite there yet.

Journal: Polskie Archiwum Medycyny Wewnetrznej 20090101

Title: Use of anticoagulants in elderly patients: practical recommendations.

Journal: Clinical interventions in aging 20090101

Title: Dabigatran etexilate: future directions in anticoagulant treatment.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20090101

Title: Dabigatran etexilate for the prophylaxis of venous thromboembolism after hip or knee replacement rationale for dose regimen.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20090101

Title: Pharmacology, pharmacokinetics, and pharmacodynamics of dabigatran etexilate, an oral direct thrombin inhibitor.

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20090101

Title: Oral antithrombotic inhibitors: dabigatran etexilate, meeting an unmet need?

Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20090101

Title: The prevention and treatment of venous thromboembolism with LMWHs and new anticoagulants.

Journal: Vascular health and risk management 20090101

Title: [Dabigatran and rivaroxaban, new oral anticoagulants for the treatment of venous thromboembolism].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101

Title: [Pharmacokinetics and pharmacodynamics of the new oral anticoagulants dabigatran and rivaroxaban].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20090101

Title: [From old to new anticoagulants: the role of the biologist].

Journal: Annales de biologie clinique 20090101

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Tags:211914-51-1 Molecular Formula|211914-51-1 MDL|211914-51-1 SMILES|211914-51-1 3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid