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22204-24-6,MFCD00072037
Catalog No.:AA00I4AK

22204-24-6 | Pyrantel pamoate

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Purity
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Price(USD)
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1g
98%(HPLC)
in stock  
$24.00   $17.00
- +
5g
≥95%
in stock  
$53.00   $37.00
- +
10g
≥95%
in stock  
$98.00   $68.00
- +
25g
97%
in stock  
$137.00   $96.00
- +
100g
97%
in stock  
$261.00   $183.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I4AK
Chemical Name:
Pyrantel pamoate
CAS Number:
22204-24-6
Molecular Formula:
C34H30N2O6S
Molecular Weight:
594.6768
MDL Number:
MFCD00072037
SMILES:
OC(=O)c1cc2ccccc2c(c1O)Cc1c(O)c(cc2c1cccc2)C(=O)O.CN1CCCN=C1/C=C/c1cccs1
Properties
Properties
 
Form:
Solid  
MP:
266-267°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
816  
Covalently-Bonded Unit Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  

Literature

Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

Journal: Chemico-biological interactions 20130905

Title: Efficacy of major anthelmintics against horse cyathostomins in France.

Journal: Veterinary parasitology 20120910

Title: Hyperthemia after cardiac surgery due to ascariasis in a child: report of a case.

Journal: General thoracic and cardiovascular surgery 20120701

Title: Pinworm in pregnancy.

Journal: Journal of midwifery & women's health 20120101

Title: Further evaluation in field tests of the activity of three anthelmintics (fenbendazole, oxibendazole, and pyrantel pamoate) against the ascarid Parascaris equorum in horse foals on eight farms in Central Kentucky (2009-2010).

Journal: Parasitology research 20111001

Title: [Albendazole in Japanese juvenile with enterobiasis in whom pyrantel pamoate is not effective].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20110901

Title: Moniliformis moniliformis infection in two Florida toddlers.

Journal: The Pediatric infectious disease journal 20110801

Title: Synergic effect of metronidazole and pyrantel pamoate on Giardia lamblia.

Journal: Parasitology international 20110101

Title: Unusual colonoscopic view of Enterobius vermicularis.

Journal: Internal medicine (Tokyo, Japan) 20110101

Title: Massive proteinuria: a possible side effect of pyrantel pamoate?

Journal: Renal failure 20110101

Title: Mechanisms underlying gut dysfunction in a murine model of chronic parasitic infection.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20101201

Title: Prevalence of the intestinal flukes Haplorchis taichui and H. yokogawai in a mountainous area of Phongsaly Province, Lao PDR.

Journal: The Korean journal of parasitology 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.

Journal: Nature chemical biology 20101101

Title: Adsorption of pyrantel pamoate on mercury from aqueous solutions: studies by stripping voltammetry.

Journal: Journal of colloid and interface science 20101001

Title: Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.

Journal: Molecular pharmacology 20101001

Title: Are macrocyclic lactones useful drugs for the treatment of Parascaris equorum infections in foals?

Journal: Veterinary parasitology 20100827

Title: Efficacy of pyrantel pamoate and ivermectin paste formulations against naturally acquired Oxyuris equi infections in horses.

Journal: Veterinary parasitology 20100715

Title: Efficacy of pyrantel pamoate against a macrocyclic lactone-resistant isolate of Parascaris equorum in horses.

Journal: Veterinary parasitology 20100715

Title: [A case of ascariasis in the gallbladder successfully treated with an anthelmintic injection into the gallbladder via a percutaneous transhepatic catheter].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20100501

Title: [Hookworm discovered in a patient presenting with severe iron-deficiency anemia].

Journal: Medecine tropicale : revue du Corps de sante colonial 20100401

Title: [A survey on anthelmintic resistance in Strongyles to ivermectin and pyrantel and macrocyclic lactone-resistance in Parascaris equorum].

Journal: Turkiye parazitolojii dergisi 20100101

Title: Treatment of naturally occurring, asymptomatic Giardia sp. in dogs with Drontal Plus flavour tablets.

Journal: Parasitology research 20090801

Title: Synergistic effect of febantel and pyrantel embonate in elimination of Giardia in a gerbil model.

Journal: Parasitology research 20090801

Title: Field effectiveness of pyrantel and failure of Parascaris equorum egg count reduction following ivermectin treatment in Italian horse farms.

Journal: Veterinary parasitology 20090406

Title: Ascariasis-associated worm encephalopathy in a young child.

Journal: Tropical doctor 20090401

Title: Influence of Bi 58 Nowy (38% dimethoate) on pyrantel embonate concentration in the liver of rats.

Journal: Polish journal of veterinary sciences 20090101

Title: Education and imaging. Gastrointestinal: ascariasis.

Journal: Journal of gastroenterology and hepatology 20081101

Title: Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs.

Journal: Parasitology research 20081001

Title: Evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (Parascaris equorum) in field studies on five farms in Central Kentucky in 2007.

Journal: Parasitology research 20080701

Title: Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis.

Journal: JAMA 20080423

Title: Study (1991 to 2001) of drug-resistant Population B small strongyles in critical tests in horses in Kentucky at the termination of a 40-year investigation.

Journal: Parasitology research 20070801

Title: Macrocyclic lactone-resistant Parascaris equorum on stud farms in Canada and effectiveness of fenbendazole and pyrantel pamoate.

Journal: Veterinary parasitology 20070430

Title: Field evaluation of the efficacy and the safety of a combination of oxantel/pyrantel/praziquantel in the treatment of naturally acquired gastrointestinal nematode and/or cestode infestations in dogs in Europe.

Journal: Veterinary parasitology 20070410

Title: Comparison of various anthelmintic therapies for the treatment of Trypanoxyuris microon infection in owl monkeys (Aotus nancymae).

Journal: Comparative medicine 20070401

Title: A field study on the effect of some anthelmintics on cyathostomins of horses in sweden.

Journal: Veterinary research communications 20070101

Title: Dose-confirmation studies of the cestocidal activity of pyrantel pamoate paste in horses.

Journal: Veterinary parasitology 20060615

Title: High transmission rates restore expression of genetically determined susceptibility of mice to nematode infections.

Journal: Parasitology 20060501

Title: Pinning down pinworms.

Journal: Nursing 20060501

Title: Comparative effects of milbemycin oxime-based and febantel-pyrantel embonate-based anthelmintic tablets on Toxocara canis egg shedding in naturally infected pups.

Journal: Veterinary parasitology 20060430

Title: Clinical field efficacy and safety of pyrantel pamoate paste (19.13% w/w pyrantel base) against Anoplocephala spp. in naturally infected horses.

Journal: Veterinary parasitology 20060415

Title: Coprological study on intestinal helminths in Swiss dogs: temporal aspects of anthelminthic treatment.

Journal: Parasitology research 20060301

Title: Strongyle egg shedding consistency in horses on farms using selective therapy in Denmark.

Journal: Veterinary parasitology 20060218

Title: Pyrantel pamoate resistance in horses receiving daily administration of pyrantel tartrate.

Journal: Journal of the American Veterinary Medical Association 20060101

Title: Residues of dimethoate in the liver and AchE activity in blood of rats after exposure to dimethoate, and dimethoate and pyrantel embonate.

Journal: Polish journal of veterinary sciences 20060101

Title: Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs.

Journal: Experimental parasitology 20051201

Title: Poor efficacy of the most commonly used anthelmintics in sport horse nematodes in Morocco in relation to resistance.

Journal: Parasite (Paris, France) 20051201

Title: Management of biliary ascariasis in pregnancy.

Journal: World journal of surgery 20051001

Title: Assessment of frequency, transmission, and genitourinary complications of enterobiasis (pinworms).

Journal: International journal of dermatology 20051001

Title: Effects of repeated anthelmintic treatment on Enterobius vermicularis infection in chimpanzees.

Journal: The Journal of parasitology 20050601

Title: Identification of strongyle eggs from anthelmintic-treated horses using a PCR-ELISA based on intergenic DNA sequences.

Journal: Parasitology research 20050301

Title: Target animal safety and tolerance study of pyrantel pamoate paste (19.13% w/w pyrantel base) administered orally to horses.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20050101

Title: Prevalence of anthelmintic resistant cyathostomes on horse farms.

Journal: Journal of the American Veterinary Medical Association 20040915

Title: Benzimidazole resistance in cyathostomin populations on horse farms in western Anatolia, Turkey.

Journal: Parasitology research 20040801

Title: A modified critical test for the efficacy of pyrantel pamoate for Anoplocephala perfoliata in equids.

Journal: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20040401

Title: Population-S benzimidazole- and tetrahydropyrimidine-resistant small strongyles in a pony herd in Kentucky (1977-1999): effects of anthelmintic treatment on the parasites as determined in critical tests.

Journal: Parasitology research 20031101

Title: Expulsion of small strongyle nematodes (cyathostomin spp) following deworming of horses on a stud farm in Sweden.

Journal: Veterinary parasitology 20030814

Title: Growth of Enterobius vermicularis in a chimpanzee after anthelmintic treatment.

Journal: The Journal of parasitology 20030601

Title: Anthelmintic treatment in horses: the extra-label use of products and the danger of under-dosing.

Journal: Journal of the South African Veterinary Association 20030601

Title: Serum mineral levels in children with intestinal parasitic infection.

Journal: Digestive diseases (Basel, Switzerland) 20030101

Title: Ziprasidone and migraine headache.

Journal: The American journal of psychiatry 20020801

Title: Strongyloides stercoralis infection with bloody pericardial effusion in a non-immunosuppressed patient.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20020601

Title: Comparison of the structures of natural and re-established populations of Ascaris in humans in a rural community of Jiangxi, China.

Journal: Parasitology 20020601

Title: Efficacy of pyrantel embonate, febantel and praziquantel against Giardia species in naturally infected adult dogs.

Journal: The Veterinary record 20020209

Title: An in vivo evaluation of induction of abnormal sperm morphology by some anthelmintic drugs in mice.

Journal: Mutation research 20011018

Title: Prevalence and clinical implications of anthelmintic resistance in cyathostomes of horses.

Journal: Journal of the American Veterinary Medical Association 20010615

Title: Resistance against migrating ascaris suum larvae in pigs immunized with infective eggs or adult worm antigens.

Journal: Parasitology 20010601

Title: Pharmacokinetic disposition and faecal excretion of pyrantel embonate following oral administration in horses.

Journal: Journal of veterinary pharmacology and therapeutics 20010201

Title: Continuance of studies on Population S benzimidazole-resistant small strongyles in a Shetland pony herd in Kentucky: effect of pyrantel pamoate (1992-1999).

Journal: Veterinary parasitology 20010120

Title: Electron and video-light microscopy analysis of the in vitro effects of pyrantel pamoate on Giardia lamblia.

Journal: Experimental parasitology 20010101

Title: Antituberculosis activity of certain antifungal and antihelmintic drugs.

Journal: Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 19990101

Title: Martin RJ, et, al. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. Int J Parasitol. 2004 Aug;34(9):1083-90.

Title: Tritten L, et, al. In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections. PLoS Negl Trop Dis. 2011 Dec;5(12):e1457.

Title: Kopp SR, et, al. Pyrantel in small animal medicine: 30 years on. Vet J. 2008 Nov;178(2):177-84.

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