Home PEG Linkers 287174-32-7
287174-32-7,MFCD27635155
Catalog No.:AA00I5AC

287174-32-7 | Hydroxy-PEG1-CH2CO2tBu

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Purity
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100mg
98%
in stock  
$19.00   $14.00
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250mg
98%
in stock  
$32.00   $22.00
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1g
98%
in stock  
$54.00   $38.00
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5g
98%
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$233.00   $164.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I5AC
Chemical Name:
Hydroxy-PEG1-CH2CO2tBu
CAS Number:
287174-32-7
Molecular Formula:
C8H16O4
Molecular Weight:
176.2102
MDL Number:
MFCD27635155
SMILES:
OCCOCC(=O)OC(C)(C)C
Properties
Computed Properties
 
Complexity:
137  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
0.3  

Downstream Synthesis Route

[1]BioorganicandMedicinalChemistryLetters,2000,vol.10,p.915-918

tert-butyl2-2-tert-butyl(dimethyl)silyloxyethoxyacetate 
  287174-32-7 

[1]BioorganicandMedicinalChemistryLetters,2000,vol.10,p.915-918

[2]Patent:WO2020/132174,2020,A1.Locationinpatent:Paragraph000835

287174-32-7   
C8H14O4 

[1]AngewandteChemie-InternationalEdition,2012,vol.51,p.11540-11544    Angew.Chem.,2012,vol.124,p.11708-11712,5

124-63-0    287174-32-7   
tert-butyl2-(2-((methylsulfonyl)oxy)ethoxy)acetate 

[1]InorganicChemistry,2013,vol.52,p.4084-4096

[2]Patent:WO2018/119441,2018,A1.Locationinpatent:Paragraph00703-00705

[1]InorganicChemistry,2013,vol.52,p.4084-4096

[2]Patent:WO2019/89422,2019,A1.Locationinpatent:Paragraph0157

[3]Patent:WO2015/867,2015,A1.Locationinpatent:Page/Pagecolumn38-39

[4]Patent:WO2018/140809,2018,A1.Locationinpatent:Paragraph00442;00594;00595

[5]Patent:WO2020/51564,2020,A1.Locationinpatent:Paragraph2266;2267

[6]ACSMedicinalChemistryLetters,2019,vol.10,p.767-772

[7]Patent:CN111233661,2020,A.Locationinpatent:Paragraph0299-0300;0303-0304

[8]Patent:WO2016/118666,2016,A1.Locationinpatent:Paragraph0798;0799

[9]Patent:WO2017/30814,2017,A1.Locationinpatent:Paragraph00297;00298

[10]Patent:WO2018/119441,2018,A1.Locationinpatent:Paragraph00701;00702

[11]Patent:WO2019/32743,2019,A1.Locationinpatent:Paragraph0459

[12]JournalofMedicinalChemistry,2021,vol.64,p.10167-10184

[13]Patent:CN113149981,2021,A.Locationinpatent:Paragraph0218-0220;0227-0229

Literature

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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SDS
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