Home Fluorides 459424-38-5
459424-38-5,MFCD07995053
Catalog No.:AA00I8H2

459424-38-5 | Fluorocholine chloride

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1g
98%
in stock  
$44.00   $31.00
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5g
98%
in stock  
$212.00   $149.00
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25g
96%
in stock  
$1,000.00   $700.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I8H2
Chemical Name:
Fluorocholine chloride
CAS Number:
459424-38-5
Molecular Formula:
C5H13ClFNO
Molecular Weight:
157.6142
MDL Number:
MFCD07995053
SMILES:
OCC[N+](CF)(C)C.[Cl-]
NSC Number:
720948
Properties
Properties
 
Form:
Solid  
MP:
>160°C (dec.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
65.4  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:THEQUEEN'SMEDICALCENTER-WO2005/9928,2005,A2Locationinpatent:Page/Pagecolumn25

108-01-0    593-70-4    459424-38-5   
N,N-dimethyl-N-fluoromethylethanolamine 

[1]CurrentPatentAssignee:DUKEUNIVERSITY-US2002/61279,2002,A1

[1]CurrentPatentAssignee:JIANGSUHENGRUIMEDICINECO.,LTD.-EP4063381,2022,A1Locationinpatent:Paragraph0057-0059

Literature

Title: Combined 18F-fluorocholine and 18F-fluoride positron emission tomography/computed tomography imaging for staging of high-risk prostate cancer.

Journal: BJU international 20121101

Title: A pilot comparison of 18F-fluorodeoxyglucose and 18F-fluorocholine PET/CT to predict early recurrence of unifocal hepatocellular carcinoma after surgical resection.

Journal: Nuclear medicine communications 20120701

Title: Detection of recurrent prostate cancer with 18F-fluorocholine PET/CT in relation to PSA level at the time of imaging.

Journal: Annals of nuclear medicine 20120701

Title: 18F-fluorocholine for prostate cancer imaging: a systematic review of the literature.

Journal: Prostate cancer and prostatic diseases 20120301

Title: Feasibility of TCP-based dose painting by numbers applied to a prostate case with (18)F-choline PET imaging.

Journal: Zeitschrift fur medizinische Physik 20120201

Title: Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancer.

Journal: Clinical and translational science 20120201

Title: Supraclavicular metastasis in prostate cancer detected with 18F-fluorocholine PET/CT.

Journal: Revista espanola de medicina nuclear e imagen molecular 20120101

Title: Dose-escalation using intensity-modulated radiotherapy for prostate cancer - evaluation of quality of life with and without (18)F-choline PET-CT detected simultaneous integrated boost.

Journal: Radiation oncology (London, England) 20120101

Title: [Clinical application of fluorocholine positron emission tomography in relapsed prostate cancer].

Journal: Actas urologicas espanolas 20120101

Title: ¹⁸F-Fluorocholine integrated PET/MRI for the initial staging of prostate cancer.

Journal: European journal of nuclear medicine and molecular imaging 20111201

Title: Fluorocholine (18F) and sodium fluoride (18F) PET/CT in the detection of prostate cancer: prospective comparison of diagnostic performance determined by masked reading.

Journal: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20110801

Title: Dose-on-demand of diverse 18F-fluorocholine derivatives through a two-step microfluidic approach.

Journal: Nuclear medicine and biology 20110701

Title: Differentiation of hepatocellular adenoma and focal nodular hyperplasia using 18F-fluorocholine PET/CT.

Journal: European journal of nuclear medicine and molecular imaging 20110301

Title: Promising role of [18F] fluorocholine PET/CT vs [18F] fluorodeoxyglucose PET/CT in primary brain tumors-early experience.

Journal: Clinical neurology and neurosurgery 20110201

Title: Prostate cancer: PET with 18F-FDG, 18F- or 11C-acetate, and 18F- or 11C-choline.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110101

Title: [¹⁸F]-fluorocholine positron-emission/computed tomography for lymph node staging of patients with prostate cancer: preliminary results of a prospective study.

Journal: BJU international 20110101

Title: Radiosynthesis and pre-clinical evaluation of [(18)F]fluoro-[1,2-(2)H(4)]choline.

Journal: Nuclear medicine and biology 20110101

Title: PET with (18)F-labelled choline-based tracers for tumour imaging: a review of the literature.

Journal: European journal of nuclear medicine and molecular imaging 20101101

Title: Detection of hepatocellular carcinoma with PET/CT: a prospective comparison of 18F-fluorocholine and 18F-FDG in patients with cirrhosis or chronic liver disease.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101101

Title: Brain F-18 Fluorocholine PET/CT for the assessment of optic pathway glioma in neurofibromatosis-1.

Journal: Clinical nuclear medicine 20101001

Title: [18F]-fluorocholine positron-emission/computed tomography for lymph node staging of patients with prostate cancer: preliminary results of a prospective study.

Journal: BJU international 20100901

Title: Pilot comparison of F-fluorocholine and F-fluorodeoxyglucose PET/CT with conventional imaging in prostate cancer.

Journal: Journal of medical imaging and radiation oncology 20100801

Title: Detection of bronchioloalveolar cancer by means of PET/CT and 18F-fluorocholine, and comparison with 18F-fluorodeoxyglucose.

Journal: Nuclear medicine communications 20100501

Title: 18F choline PET/CT in the preoperative staging of prostate cancer in patients with intermediate or high risk of extracapsular disease: a prospective study of 130 patients.

Journal: Radiology 20100301

Title: Detection of synchronous primary breast and prostate cancer by F-18 fluorocholine PET/CT.

Journal: Clinical nuclear medicine 20100201

Title: Biokinetics of 18F-choline studied in four prostate cancer patients.

Journal: Radiation protection dosimetry 20100101

Title: [The use of 18F-fluorothymidine and 18F-fluorocholine in imaging with positron emission tomography].

Journal: Hellenic journal of nuclear medicine 20100101

Title: Dose-escalation using intensity-modulated radiotherapy for prostate cancer--evaluation of the dose distribution with and without 18F-choline PET-CT detected simultaneous integrated boost.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20091101

Title: 18F-fluorocholine PET-guided target volume delineation techniques for partial prostate re-irradiation in local recurrent prostate cancer.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20091101

Title: Influence of multidrug resistance on (18)F-FCH cellular uptake in a glioblastoma model.

Journal: European journal of nuclear medicine and molecular imaging 20090801

Title: Three-phase 18F-fluorocholine PET/CT in the evaluation of prostate cancer recurrence.

Journal: Nuklearmedizin. Nuclear medicine 20090101

Title: Comparison of [18F]-tracers in various experimental tumor models by PET imaging and identification of an early response biomarker for the novel microtubule stabilizer patupilone.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090101

Title: Detection of bone metastases in patients with prostate cancer by 18F fluorocholine and 18F fluoride PET-CT: a comparative study.

Journal: European journal of nuclear medicine and molecular imaging 20081001

Title: Prostate biopsy guided by 18F-fluorocholine PET in men with persistently elevated PSA levels.

Journal: European journal of nuclear medicine and molecular imaging 20080801

Title: Biodisposition and metabolism of [(18)F]fluorocholine in 9L glioma cells and 9L glioma-bearing fisher rats.

Journal: European journal of nuclear medicine and molecular imaging 20080601

Title: The value of 18F-choline PET/CT in patients with elevated PSA-level and negative prostate needle biopsy for localisation of prostate cancer.

Journal: European journal of nuclear medicine and molecular imaging 20080501

Title: Fully automated [18F]fluorocholine synthesis in the TracerLab MX FDG Coincidence synthesizer.

Journal: Nuclear medicine and biology 20080201

Title: In vitro and in vivo studies with [(18)F]fluorocholine on digestive tumoral cell lines and in an animal model of metastasized endocrine tumor.

Journal: Nuclear medicine and biology 20080101

Title: Use of step-section histopathology to evaluate 18F-fluorocholine PET sextant localization of prostate cancer.

Journal: Molecular imaging 20080101

Title: (18)F-labeled positron emission tomographic radiopharmaceuticals in oncology: an overview of radiochemistry and mechanisms of tumor localization.

Journal: Seminars in nuclear medicine 20071101

Title: Cancer imaging with fluorine-18-labeled choline derivatives.

Journal: Seminars in nuclear medicine 20071101

Title: [18F]fluorocholine PET/CT in the assessment of bone metastases in prostate cancer.

Journal: European journal of nuclear medicine and molecular imaging 20070801

Title: Solitary brain lesions enhancing at MR imaging: evaluation with fluorine 18 fluorocholine PET.

Journal: Radiology 20070801

Title: Uptake of 18F-Fluorocholine, 18F-FET, and 18F-FDG in C6 gliomas and correlation with 131I-SIP(L19), a marker of angiogenesis.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070401

Title: Asymmetric F-18 fluorocholine uptake of submaxillary glands revealing intraglandular lithiasis.

Journal: Clinical nuclear medicine 20070201

Title: [18F]fluorocholine PET/CT imaging for the detection of recurrent prostate cancer at PSA relapse: experience in 100 consecutive patients.

Journal: European journal of nuclear medicine and molecular imaging 20061201

Title: 18F-choline PET/CT for initial staging of advanced prostate cancer.

Journal: AJR. American journal of roentgenology 20061201

Title: PET/CT in patients with hepatocellular carcinoma using [(18)F]fluorocholine: preliminary comparison with [(18)F]FDG PET/CT.

Journal: European journal of nuclear medicine and molecular imaging 20061101

Title: Detection of pelvic lymph node metastases in patients with clinically localized prostate cancer: comparison of [18F]fluorocholine positron emission tomography-computerized tomography and laparoscopic radioisotope guided sentinel lymph node dissection.

Journal: The Journal of urology 20061101

Title: Uptake of 18F-fluorocholine, 18F-fluoro-ethyl-L: -tyrosine and 18F-fluoro-2-deoxyglucose in F98 gliomas in the rat.

Journal: European journal of nuclear medicine and molecular imaging 20060601

Title: Localization of primary prostate cancer with dual-phase 18F-fluorocholine PET.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060201

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