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475-31-0,MFCD00065902
Catalog No.:AA00I8L2

475-31-0 | Glycine, N-[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]-

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1g
98%(HPLC)
in stock  
$32.00   $23.00
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5g
98%(HPLC)
in stock  
$96.00   $67.00
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10g
98%(HPLC)
in stock  
$183.00   $128.00
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25g
98%(HPLC)
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I8L2
Chemical Name:
Glycine, N-[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]-
CAS Number:
475-31-0
Molecular Formula:
C26H43NO6
Molecular Weight:
465.6227
MDL Number:
MFCD00065902
SMILES:
O[C@@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2C[C@H](O)[C@]2(C1CC[C@@H]2[C@@H](CCC(=O)NCC(=O)O)C)C)O)C
Properties
Properties
 
BP:
692.042 °C at 760 mmHg  
Form:
Solid  
MP:
128 °C  
Refractive Index:
1.6000 (estimate)  
Solubility:
methanol: 0.1 g/mL, clear, colorless  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
759  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
11  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
6  
XLogP3:
2.9  

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Title: Complexation of tauro- and glyco-conjugated bile salts with α-cyclodextrin and hydroxypropyl-α-cyclodextrin studied by affinity capillary electrophoresis and molecular modelling.

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Title: Enhanced transbuccal salmon calcitonin (sCT) delivery: effect of chemical enhancers and electrical assistance on in vitro sCT buccal permeation.

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Journal: International journal of pharmaceutics 20110915

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Title: Oral delivery system for two-pulse colonic release of protein drugs and protease inhibitor/absorption enhancer compounds.

Journal: Journal of pharmaceutical sciences 20110801

Title: Purification and characterization of a protein capable of binding to fatty acids and bile salts in Giardia lamblia.

Journal: The Journal of parasitology 20110801

Title: Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20110801

Title: Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma.

Journal: Molecular & cellular proteomics : MCP 20110701

Title: Serum 27-nor-5β-cholestane-3,7,12,24,25 pentol glucuronide discovered by metabolomics as potential diagnostic biomarker for epithelium ovarian cancer.

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Journal: Steroids 20110501

Title: [Clinical analysis of fetal death cases in intrahepatic cholestasis of pregnancy].

Journal: Zhonghua fu chan ke za zhi 20110501

Title: A serum metabonomic study on the difference between alcohol- and HBV-induced liver cirrhosis by ultraperformance liquid chromatography coupled to mass spectrometry plus quadrupole time-of-flight mass spectrometry.

Journal: Chinese medical journal 20110501

Title: Bile acid-binding ability of kaki-tannin from young fruits of persimmon (Diospyros kaki) in vitro and in vivo.

Journal: Phytotherapy research : PTR 20110401

Title: A sensitive method for qualitative screening of bile salt hydrolase-active lactobacilli based on thin-layer chromatography.

Journal: Journal of dairy science 20110401

Title: Investigating the effects of physiological bile acids on GLP-1 secretion and glucose tolerance in normal and GLP-1R(-/-) mice.

Journal: Biological chemistry 20110401

Title: Antifungal evaluation of cholic acid and its derivatives on Candida albicans by microcalorimetry and chemometrics.

Journal: Analytica chimica acta 20110318

Title: Plasma metabolomic profile in nonalcoholic fatty liver disease.

Journal: Metabolism: clinical and experimental 20110301

Title: Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.

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Journal: International journal of pharmaceutics 20081119

Title: Inhibit multidrug resistance and induce apoptosis by using glycocholic acid and epirubicin.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080902

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Title: Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.

Journal: Journal of medicinal chemistry 20080327

Title: Blending effects on adsorption and micellization of different membrane protein solubilizers II. A thermodynamic study on a mixed system of CHAPS with a bile salt in pH 7.4 phosphate buffer solution.

Journal: Colloids and surfaces. B, Biointerfaces 20080315

Title: Physical incorporation of NADPH-cytochrome P450 reductase and cytochrome P450 into phospholipid vesicles using glycocholate and Bio-Beads.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080301

Title: Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases.

Journal: International journal of nanomedicine 20080301

Title: Activation of MUC1 mucin expression by bile acids in human esophageal adenocarcinomatous cells and tissues is mediated by the phosphatidylinositol 3-kinase.

Journal: Surgery 20080101

Title: Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model.

Journal: Molecular systems biology 20080101

Title: Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity.

Journal: Molecular systems biology 20080101

Title: Design and in vitro characterization of buccoadhesive drug delivery system of insulin.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Long-term biokinetics and radiation exposure of patients undergoing 14C-glycocholic acid and 14C-xylose breath tests.

Journal: Cancer biotherapy & radiopharmaceuticals 20071201

Title: Lipid-based colloidal carriers for peptide and protein delivery--liposomes versus lipid nanoparticles.

Journal: International journal of nanomedicine 20071201

Title: Complexation of tauro- and glyco-conjugated bile salts with three neutral beta-CDs studied by ACE.

Journal: Electrophoresis 20071001

Title: The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070901

Title: Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation.

Journal: AAPS PharmSciTech 20070901

Title: Structure-interaction relationships between the bile acid GCA and pharmaceuticals using multivariate data analysis and capillary electrophoresis.

Journal: Journal of pharmaceutical sciences 20070801

Title: Bile salt-dependent efflux of cellular phospholipids mediated by ATP binding cassette protein B4.

Journal: Hepatology (Baltimore, Md.) 20070701

Title: Structural basis for bile salt inhibition of pancreatic phospholipase A2.

Journal: Journal of molecular biology 20070601

Title: Kinetic mechanism of ligand binding in human ileal bile acid binding protein as determined by stopped-flow fluorescence analysis.

Journal: Biochemistry 20070508

Title: Influence of sodium glycocholate on production of conjugated linoleic acid by cells of Lactobacillus reuteri ATCC 55739.

Journal: Journal of food science 20070501

Title: Novel cationic and neutral glycocholic acid and polyamine conjugates able to inhibit transporters involved in hepatic and intestinal bile acid uptake.

Journal: Bioorganic & medicinal chemistry 20070315

Title: Nanomedicines in renal transplant rejection--focus on sirolimus.

Journal: International journal of nanomedicine 20070301

Title: Biosynthesis of bile acids in a variety of marine bacterial taxa.

Journal: Journal of microbiology and biotechnology 20070301

Title: Inhibition of the intestinal absorption of bile acids using cationic derivatives: mechanism and repercussions.

Journal: Biochemical pharmacology 20070201

Title: Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach.

Journal: Digestive diseases and sciences 20070201

Title: Bile salt hydrolase, the member of Ntn-hydrolase family: differential modes of structural and functional transitions during denaturation.

Journal: IUBMB life 20070201

Title: In silico prediction of pregnane X receptor activators by machine learning approaches.

Journal: Molecular pharmacology 20070101

Title: [Impairment of humoral regulation of exocrine pancreatic function in chronic pancreatitis].

Journal: Terapevticheskii arkhiv 20070101

Title: A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model.

Journal: Molecular systems biology 20070101

Title: Gene expression changes associated with Barrett's esophagus and Barrett's-associated adenocarcinoma cell lines after acid or bile salt exposure.

Journal: BMC gastroenterology 20070101

Title: Functional evolution of the vitamin D and pregnane X receptors.

Journal: BMC evolutionary biology 20070101

Title: Colesevelam: a review of its use in hypercholesterolemia.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

Title: Investigation of microencapsulated BSH active lactobacillus in the simulated human GI tract.

Journal: Journal of biomedicine & biotechnology 20070101

Title: Bile acid salt binding with colesevelam HCl is not affected by suspension in common beverages.

Journal: Journal of pharmaceutical sciences 20061201

Title: [Multi-dimensional fingerprints of Japan Jiuxin pill].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20061201

Title: Individual dissolution of single-walled carbon nanotubes in aqueous solutions of steroid or sugar compounds and their Raman and near-IR spectral properties.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20061010

Title: Repair of DNA damage induced by bile salts in Salmonella enterica.

Journal: Genetics 20061001

Title: [Bile salts induce differentiation in cultured human normal esophageal mucosal epithelial cells].

Journal: Zhonghua yi xue za zhi 20060912

Title: Characterization of fasted-state human intestinal fluids collected from duodenum and jejunum.

Journal: The Journal of pharmacy and pharmacology 20060801

Title: Effects of choleretics on bile compositions drained from patients with pigment gallstone.

Journal: Chinese journal of integrative medicine 20060601

Title: Excellent absorption enhancing characteristics of NO donors for improving the intestinal absorption of poorly absorbable compound compared with conventional absorption enhancers.

Journal: Drug metabolism and pharmacokinetics 20060601

Title: Single-step analysis of individual conjugated bile acids in human bile using 1H NMR spectroscopy.

Journal: Lipids 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Repeated administration of a vitamin preparation containing glycocholic acid in patients with hepatobiliary disease.

Journal: Alimentary pharmacology & therapeutics 20060501

Title: Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060401

Title: Colon-specific delivery and enhanced colonic absorption of [Asu(1,7)]-eel calcitonin using chitosan capsules containing various additives in rats.

Journal: Journal of drug targeting 20060401

Title: Xanthomonas maltophilia CBS 897.97 as a source of new 7beta- and 7alpha-hydroxysteroid dehydrogenases and cholylglycine hydrolase: improved biotransformations of bile acids.

Journal: Steroids 20060301

Title: Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol.

Journal: Journal of pharmaceutical sciences 20060201

Title: [Clinical and experimental study on wuling pill in treating gestation period intrahepatic cholestasis].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20060201

Title: Determinants of cooperativity and site selectivity in human ileal bile acid binding protein.

Journal: Biochemistry 20060124

Title: Effects of absorption promoters on insulin absorption through colon-targeted delivery.

Journal: International journal of pharmaceutics 20060113

Title: Effect of tamoxifen and raloxifene on the conjugation of bile acids with taurine and glycine in ovariectomized rats.

Journal: Pharmacological reports : PR 20060101

Title: Adsorption of bile acid by chitosan salts prepared with cinnamic acid and analogue compounds.

Journal: Journal of biomaterials science. Polymer edition 20060101

Title: Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine.

Journal: The Journal of biological chemistry 20051223

Title: Small-angle X-ray scattering and light scattering on lysozyme and sodium glycocholate micelles.

Journal: The journal of physical chemistry. B 20051222

Title: Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20051201

Title: Bile salts inhibit growth and induce apoptosis of culture human normal esophageal mucosal epithelial cells.

Journal: World journal of gastroenterology 20051107

Title: Diastereomeric molecular recognition and binding behavior of bile acids by L/D-tryptophan-modified beta-cyclodextrins.

Journal: The Journal of organic chemistry 20051028

Title: Saturated phospholipids promote crystallization but slow down polymorphic transitions in triglyceride nanoparticles.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051003

Title: Proapoptotic effect on normal and tumor intestinal cells of cytostatic drugs with enterohepatic organotropism.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: mu-Opiate receptor agonist loperamide blocks bethanechol-induced gallbladder contraction, despite higher cholecystokinin plasma levels in man.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20051001

Title: Alternative delivery of insulin via eye drops.

Journal: Diabetes technology & therapeutics 20051001

Title: 1H and 13C NMR characterization and stereochemical assignments of bile acids in aqueous media.

Journal: Lipids 20051001

Title: Development of a 13C-glycocholic acid blood test to assess bacterial metabolic activity of the small intestine in canines.

Journal: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20051001

Title: Bile salts inhibit growth and induce apoptosis of human esophageal cancer cell line.

Journal: World journal of gastroenterology 20050907

Title: [Cholyl glycine (CG)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050801

Title: Octreotide induced prolongation of colonic transit increases faecal anaerobic bacteria, bile acid metabolising enzymes, and serum deoxycholic acid in patients with acromegaly.

Journal: Gut 20050501

Title: Improvement of absorption enhancing effects of n-dodecyl-beta-D-maltopyranoside by its colon-specific delivery using chitosan capsules.

Journal: International journal of pharmaceutics 20050411

Title: Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11.

Journal: Hepatology (Baltimore, Md.) 20050401

Title: High-speed digital imaging method for ciliary beat frequency measurement.

Journal: The Journal of pharmacy and pharmacology 20050401

Title: Stable ciliary activity in human nasal epithelial cells grown in a perfusion system.

Journal: International journal of pharmaceutics 20050323

Title: Molecular recognition thermodynamics of bile salts by beta-cyclodextrin dimers: Factors governing the cooperative binding of cyclodextrin dimers.

Journal: The journal of physical chemistry. B 20050310

Title: Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).

Journal: Molecular pharmacology 20050201

Title: Micellar electrokinetic chromatography of bilirubin, related compounds, and selected drugs with mixtures of binary bile salts.

Journal: Electrophoresis 20050201

Title: Quantitative estimation of the effects of bile salt surfactant systems on insulin stability and permeability in the rat intestine using a mass balance model.

Journal: The Journal of pharmacy and pharmacology 20050201

Title: Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050101

Title: The influence of the ionic medium on the behaviour of sodium glycocholate and cholate aqueous solutions.

Journal: Annali di chimica 20050101

Title: Inhibition of MRP1-mediated efflux in human erythrocytes by mono-anionic bile salts.

Journal: Anticancer research 20050101

Title: Effect of tibolone on turnover of cholesterol to bile acids in ovariectomized rats.

Journal: Menopause (New York, N.Y.) 20050101

Title: Composition of aqueous solutions containing sodium glycocholate and glycodeoxycholate.

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Title: Noninvasive methods to determine the critical micelle concentration of some bile acid salts.

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Title: Evaluation of different toxicity assays applied to proliferating cells and to stratified epithelium in relation to permeability enhancement with glycocholate.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20041001

Title: Molecular recognition thermodynamics and structural elucidation of interactions between steroids and bridged bis(beta-cyclodextrin)s.

Journal: The Journal of organic chemistry 20041001

Title: Adsorption of bile acid by chitosan-orotic acid salt and its application as an oral preparation.

Journal: Chemical & pharmaceutical bulletin 20041001

Title: Biquinolino-modified beta-cyclodextrin dimers and their metal complexes as efficient fluorescent sensors for the molecular recognition of steroids.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20040806

Title: Functional assessment of bacterial colonization in patients with ileal pouch-anal anastomosis and Brooke ileostomy.

Journal: Diseases of the colon and rectum 20040801

Title: Conjugates of gadolinium complexes to bile acids as hepatocyte-directed contrast agents for magnetic resonance imaging.

Journal: Journal of medicinal chemistry 20040701

Title: Acid and bile salts induce DNA damage in human oesophageal cell lines.

Journal: Mutagenesis 20040701

Title: [Study on relationship between serum cholylglycine and placental apoptosis in patients with intrahepatic cholestasis of pregnancy].

Journal: Zhonghua fu chan ke za zhi 20040701

Title: Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers.

Journal: Journal of neurophysiology 20040501

Title: Cytotoxicity evaluation of enzyme inhibitors and absorption enhancers in Caco-2 cells for oral delivery of salmon calcitonin.

Journal: Journal of pharmaceutical sciences 20040401

Title: [Analysis on therapeutic effect of Western and Chinese drug in treating intrahepatic cholestasis pregnancy].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401

Title: Metabolism and absorption enhancement of methionine enkephalin in human nasal epithelium.

Journal: Peptides 20040401

Title: Quantification of bile acids directly from plasma by MALDI-TOF-MS.

Journal: Analytical and bioanalytical chemistry 20040301

Title: Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway.

Journal: The Biochemical journal 20040201

Title: [Effects of protease inhibitors on intestinal absorption of insulin].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040201

Title: Poly(N,N,N-trimethylammoniumalkyl acrylamide chloride) based hydrogels for serum cholesterol reduction.

Journal: Biomacromolecules 20040101

Title: Alkanoylsucroses in nasal delivery of low molecular weight heparins: in-vivo absorption and reversibility studies in rats.

Journal: The Journal of pharmacy and pharmacology 20040101

Title: Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20031101

Title: Potential utility of various protease inhibitors for improving the intestinal absorption of insulin in rats.

Journal: The Journal of pharmacy and pharmacology 20031101

Title: Steroid ring hydroxylation patterns govern cooperativity in human bile acid binding protein.

Journal: Biochemistry 20031014

Title: Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor.

Journal: Hepatology (Baltimore, Md.) 20031001

Title: Determination of ursodeoxycholic acid in pharmaceutical preparations by capillary electrophoresis with indirect UV detection.

Journal: Journal of pharmaceutical and biomedical analysis 20030808

Title: Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane.

Journal: Hepatology (Baltimore, Md.) 20030801

Title: Influence of emulsifiers on the crystallization of solid lipid nanoparticles.

Journal: Journal of pharmaceutical sciences 20030701

Title: Variation in plasma amino acid concentrations during a cycling competition.

Journal: The Journal of sports medicine and physical fitness 20030601

Title: Protease inhibitors: synthesis of bacterial collagenase and matrix metalloproteinase inhibitors incorporating arylsulfonylureido and 5-dibenzo-suberenyl/suberyl moieties.

Journal: Bioorganic & medicinal chemistry 20030515

Title: Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway.

Journal: The Journal of pharmacology and experimental therapeutics 20030501

Title: Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4).

Journal: The Biochemical journal 20030415

Title: Sensitivity of bile acid transport by organic anion-transporting polypeptides to intracellular pH.

Journal: Biochimica et biophysica acta 20030401

Title: Effect of sodium glycocholate on development of tolerance to Parthenium hysterophorus extracts.

Journal: Indian journal of experimental biology 20030401

Title: Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats.

Journal: Hepatology (Baltimore, Md.) 20030301

Title: Differential effects of metformin on bile salt absorption from the jejunum and ileum.

Journal: Diabetes, obesity & metabolism 20030301

Title: Quantification of bile acids directly from urine by MALDI-TOF-MS.

Journal: Analytical and bioanalytical chemistry 20030301

Title: Sodium glycocholate transport across Caco-2 cell monolayers, and the enhancement of mannitol transport relative to transepithelial electrical resistance.

Journal: International journal of pharmaceutics 20030218

Title: Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20030204

Title: Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030201

Title: Insights into the bile acid transportation system: the human ileal lipid-binding protein-cholyltaurine complex and its comparison with homologous structures.

Journal: Proteins 20030201

Title: Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).

Journal: Molecular pharmacology 20030201

Title: Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter.

Journal: The Biochemical journal 20030101

Title: [Comparative characteristics of lipid components of gallbladder and liver bile fractions in children with chronic cholecystitis].

Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

Title: Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A.

Journal: International journal of pharmaceutics 20021205

Title: Maldigestion and malabsorption of dietary lipid during severe childhood malnutrition.

Journal: Archives of disease in childhood 20021201

Title: The human bile salt export pump: characterization of substrate specificity and identification of inhibitors.

Journal: Gastroenterology 20021101

Title: Functional expression of the canalicular bile salt export pump of human liver.

Journal: Gastroenterology 20021101

Title: [Relationship of vascular endothelial growth factor with bile acid in intrahepatic cholestasis of pregnancy].

Journal: Zhonghua fu chan ke za zhi 20021101

Title: Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter.

Journal: Molecular endocrinology (Baltimore, Md.) 20021001

Title: A monoclonal antibody-based enzyme-linked immunosorbent assay of glycolithocholic acid sulfate in human urine for liver function test.

Journal: Steroids 20020901

Title: [Relationship between human leukocyte antigen-DRB1 allele gene polymorphism and intrahepatic cholestasis of pregnancy].

Journal: Zhonghua fu chan ke za zhi 20020901

Title: [Maternal-fetal mixed lymphocyte culture in intrahepatic cholestasis of pregnancy].

Journal: Zhonghua fu chan ke za zhi 20020901

Title: Examination of the solubilization of drugs by bile salt micelles.

Journal: Journal of pharmaceutical sciences 20020801

Title: Solubilization of drugs by physiological mixtures of bile salts.

Journal: Pharmaceutical research 20020801

Title: Buccal transport of flecainide and sotalol: effect of a bile salt and ionization state.

Journal: International journal of pharmaceutics 20020708

Title: Colesevelam hydrochloride.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020515

Title: Characterization of cloned mouse Na+/taurocholate cotransporting polypeptide by transient expression in COS-7 cells.

Journal: Bioscience, biotechnology, and biochemistry 20020501

Title: Nasal absorption enhancement strategies for therapeutic peptides: an in vitro study using cultured human nasal epithelium.

Journal: International journal of pharmaceutics 20020426

Title: Bile salt aggregates in the gas phase: an electrospray ionization mass spectrometric study.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20020415

Title: Carriers involved in targeting the cytostatic bile acid-cisplatin derivatives cis-diammine-chloro-cholylglycinate-platinum(II) and cis-diammine-bisursodeoxycholate-platinum(II) toward liver cells.

Journal: Molecular pharmacology 20020401

Title: Drug metabolic activity of cultured hepatocytes can synchronize with bile acid concentration in the medium.

Journal: Cell biochemistry and function 20020301

Title: Ocular tolerance of absorption enhancers in ophthalmic preparations.

Journal: AAPS pharmSci 20020301

Title: Nasal glucagon delivery using microcrystalline cellulose in healthy volunteers.

Journal: International journal of pharmaceutics 20020221

Title: [Observation on effect of danxiaoling in supplementary treatment of intrahepatic cholestasis in pregnancy].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020201

Title: 7alpha-OH epimerisation of bile acids via oxido-reduction with Xanthomonas maltophilia.

Journal: Steroids 20020101

Title: Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3.

Journal: Pharmaceutical research 20020101

Title: On lead(II) glycocholate solubility.

Journal: Annali di chimica 20020101

Title: Ion conductors derived from biogenic amines, bile acids, and amino acids.

Journal: Bioconjugate chemistry 20020101

Title: MRP subfamily transporters and resistance to anticancer agents.

Journal: Journal of bioenergetics and biomembranes 20011201

Title: Absorption of water-soluble compounds with different molecular weights and.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20011019

Title: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

Journal: Cancer research 20011001

Title: Pericentral hepatocytes translocate hydrophilic bile acids more rapidly than hydrophobic ones.

Journal: Digestive diseases and sciences 20011001

Title: Beneficial effects of glycocholic acid (GCA) on gut mucosal damage in bile duct ligated rats.

Journal: Inflammation 20011001

Title: Nasal bioavailability of peptide T in rabbits: absorption enhancement by sodium glycocholate and glycofurol.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010801

Title: Gastrointestinal handling and metabolic disposal of 13C-labelled tripalmitin during rehabilitation from childhood malnutrition.

Journal: The British journal of nutrition 20010601

Title: Liver organotropism and biotransformation of a novel platinum-ursodeoxycholate derivative, Bamet-UD2, with enhanced antitumour activity.

Journal: Journal of drug targeting 20010601

Title: Transbuccal peptide delivery: stability and in vitro permeation studies on endomorphin-1.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20010518

Title: Characterization of the mouse bile salt export pump overexpressed in the baculovirus system.

Journal: Hepatology (Baltimore, Md.) 20010501

Title: The effect of absorption enhancers on the initial degradation kinetics of insulin by alpha-chymotrypsin.

Journal: International journal of pharmaceutics 20010417

Title: Evaluation of insulin permeability and effects of absorption enhancers on its permeability by an in vitro pulmonary epithelial system using Xenopus pulmonary membrane.

Journal: Biological & pharmaceutical bulletin 20010401

Title: Analysis of the physicochemical interactions between Clostridium difficile toxins and cholestyramine using liquid chromatography with post-column derivatization.

Journal: Biochimica et biophysica acta 20010309

Title: Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition.

Journal: Hepatology (Baltimore, Md.) 20010301

Title: Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver.

Journal: Gastroenterology 20010201

Title: Study of partition of nitrazepam in bile salt micelles and the role of lecithin.

Journal: Journal of pharmaceutical and biomedical analysis 20010201

Title: Penetration of verapamil hydrochloride in the presence of sodium glycocholate as penetration enhancer through mucous membrane.

Journal: Die Pharmazie 20010101

Title: The lung as a route for systemic delivery of therapeutic proteins and peptides.

Journal: Respiratory research 20010101

Title: Ileal mucosal bile acid absorption is increased in Cftr knockout mice.

Journal: BMC gastroenterology 20010101

Title: Differential modulation of cellular death and survival pathways by conjugated bile acids.

Journal: BMC biochemistry 20010101

Title: Enhanced efficiency of the placental barrier to cisplatin through binding to glycocholic acid.

Journal: Anticancer research 20010101

Title: Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells.

Journal: The American journal of physiology 19980201

Title: Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver.

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Title: Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.

Journal: European journal of gastroenterology & hepatology 19960301

Title: Inhibition of amphotericin B (Fungizone) toxicity to cells by egg lecithin-glycocholic acid mixed micelles.

Journal: Antimicrobial agents and chemotherapy 19901201

Title: Biliary permeability during ethinyl estradiol-induced cholestasis studied by segmented retrograde intrabiliary injections in rats.

Journal: Journal of hepatology 19850101

Title: Substrate specificity of cholylglycine hydrolase for the hydrolysis of bile acid conjugates.

Journal: The Journal of biological chemistry 19841225

Title: Hepatic handling of bile salts and protein in the rat during intrahepatic cholestasis.

Journal: Gastroenterology 19830501

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SDS
Tags:475-31-0 Molecular Formula|475-31-0 MDL|475-31-0 SMILES|475-31-0 Glycine, N-[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]-