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Home Amines 477600-73-0
477600-73-0,MFCD16877475
Catalog No.:AA00I8MB

477600-73-0 | N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-n-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$26.00   $18.00
- +
250mg
95%
in stock  
$42.00   $29.00
- +
1g
97%
in stock  
$145.00   $102.00
- +
5g
95%
in stock  
$356.00   $249.00
- +
10g
97%
in stock  
$710.00   $497.00
- +
25g
95%
in stock  
$1,213.00   $849.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I8MB
Chemical Name:
N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-n-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine
CAS Number:
477600-73-0
Molecular Formula:
C20H25N5
Molecular Weight:
335.4460
MDL Number:
MFCD16877475
SMILES:
C[C@@H]1CCN(C[C@@H]1N(c1ncnc2c1cc[nH]2)C)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
424  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
3.6  

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartFlanagan,MarkE.;Blumenkopf,ToddA.;Brissette,WilliamH.;Brown,MatthewF.;Casavant,JeffreyM.;Shang-Poa,Chang;Doty,JonathanL.;Elliott,EileenA.;Fisher,MichaelB.;Hines,Michael;Kent,Craig;Kudlacz,ElizabethM.;Lillie,BrettM.;Magnuson,KellyS.;McCurdy,SandraP.;Munchhof,MichaelJ.;Perry,BretD.;Sawyer,PerryS.;Strelevitz,TimothyJ.;Subramanyam,Chakrapani;Sun,Jianmin;Whipple,DavidA.;Changelian,PaulS.[JournalofMedicinalChemistry,2010,vol.53,#24,p.8468-8484]

[1]CurrentPatentAssignee:MSNLABORATORIESPRIVATELIMITED;SAMSUNGELECTRONICSCO.,LTD.-US2016/122354,2016,A1

[2]CurrentPatentAssignee:SHANDONGUNIVERSITY-CN106146517,2016,A

[3]CurrentPatentAssignee:YANGTZERIVERPHARMACEUTICALGROUPCOLTD-CN107793418,2018,A

[4]CurrentPatentAssignee:LEADINGPHARMMEDICALTECH-CN109776547,2019,A

Literature

Title: Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors.

Journal: Journal of medicinal chemistry 20120628

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SDS
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Tags:477600-73-0 Molecular Formula|477600-73-0 MDL|477600-73-0 SMILES|477600-73-0 N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-n-methyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine