487-54-7,MFCD00002695
Catalog No.:AA00I8Q7

487-54-7 | 2-Hydroxyhippuric acid

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Purity
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10mg
97%
in stock  
$43.00   $30.00
- +
1g
95%
in stock  
$87.00   $61.00
- +
5g
95%
in stock  
$278.00   $195.00
- +
10g
95%
in stock  
$427.00   $299.00
- +
25g
95%
in stock  
$843.00 $590.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00I8Q7
Chemical Name:
2-Hydroxyhippuric acid
CAS Number:
487-54-7
Molecular Formula:
C9H9NO4
Molecular Weight:
195.1721
MDL Number:
MFCD00002695
SMILES:
OC(=O)CNC(=O)c1ccccc1O
Properties
Computed Properties
 
Complexity:
229  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
0.9  

Downstream Synthesis Route

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Moss;Urist;Martin[ArchivesofBiochemistry,1948,vol.19,p.213,214]

[1]Mazzotta;Giori;Guarneri;Benassi[Farmaco,EdizioneScientifica,1975,vol.30,#5,p.399-407]

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Gandhi,S.K.etal.[MonatsheftefurChemie,1967,vol.98,#5,p.1751-1753]

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Gandhi,S.K.etal.[MonatsheftefurChemie,1967,vol.98,#5,p.1751-1753]

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Gandhi,S.K.etal.[MonatsheftefurChemie,1967,vol.98,#5,p.1751-1753]

Literature

Title: Aspirin metabolites are GPR35 agonists.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20120701

Title: Salicylamide and salicylglycine oxidovanadium complexes with insulin-mimetic properties.

Journal: Journal of inorganic biochemistry 20111201

Title: Metabonomic analysis of hepatitis E patients shows deregulated metabolic cycles and abnormalities in amino acid metabolism.

Journal: Journal of viral hepatitis 20111001

Title: Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases.

Journal: Journal of nutrigenetics and nutrigenomics 20110701

Title: Antiplatelet combinations for prevention of atherothrombotic events.

Journal: Vascular health and risk management 20110101

Title: Drug structure-transport relationships.

Journal: Journal of pharmacokinetics and pharmacodynamics 20101201

Title: Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.

Journal: Bioorganic & medicinal chemistry letters 20101015

Title: Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice.

Journal: European journal of pharmacology 20100610

Title: Terbium-macrocycle complexes as chemical sensors: detection of an aspirin metabolite in urine using a salicylurate-specific receptor site.

Journal: Inorganic chemistry 20100517

Title: Quantitative analysis of clopidogrel bisulphate and aspirin by first derivative spectrophotometric method in tablets.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Serum albumin complexation of acetylsalicylic acid metabolites.

Journal: Current drug metabolism 20090601

Title: Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.

Journal: Pharmacology 20090101

Title: Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping.

Journal: International journal of nanomedicine 20090101

Title: Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid.

Journal: Journal of agricultural and food chemistry 20081224

Title: Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).

Journal: Bioorganic & medicinal chemistry 20081201

Title: Synthesis of a new seleninic acid anhydride and mechanistic studies into its glutathione peroxidase activity.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

Title: Chemometric simultaneous estimation of clopidogrel bisulphate and aspirin from combined dosage form.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: [Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs].

Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20071001

Title: UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.

Journal: Pharmacogenetics and genomics 20070801

Title: Willow leaves' extracts contain anti-tumor agents effective against three cell types.

Journal: PloS one 20070101

Title: Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070101

Title: Effect of cotreatment of aspirin metabolites on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.

Journal: Drug and chemical toxicology 20060101

Title: Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice.

Journal: Journal of agricultural and food chemistry 20050420

Title: Simultaneous determination of gentisic, salicyluric and salicylic acid in human plasma using solid-phase extraction, liquid chromatography and electrospray ionization mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041005

Title: Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.

Journal: Environmental toxicology 20041001

Title: Pharmacokinetics and metabolic rates of acetyl salicylic acid and its metabolites in an Otomi ethnic group of Mexico.

Journal: Biological & pharmaceutical bulletin 20040501

Title: Model complexes with naturally occurring ligands (salicylglycine and imidazol) and the biometals copper and cobalt.

Journal: Journal of inorganic biochemistry 20040201

Title: Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases.

Journal: Biopharmaceutics & drug disposition 20040101

Title: Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin.

Journal: Journal of clinical pathology 20030901

Title: First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine.

Journal: Analytical and bioanalytical chemistry 20021001

Title: Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.

Journal: British journal of pharmacology 20020101

Title: Identification and determination of salicylic acid and salicyluric acid in urine of people not taking salicylate drugs.

Journal: Annals of clinical biochemistry 20020101

Title: Pharmacokinetics of salicin after oral administration of a standardised willow bark extract.

Journal: European journal of clinical pharmacology 20010801

Title: Synthesis and evaluation of the analgesic and antiinflammatory activities of O-substituted salicylamides.

Journal: Archives of pharmacal research 20010601

Title: Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.

Journal: Journal of chemical ecology 20010601

Title: Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010305

Title: Potentiometric and spectroscopic studies on the dimethyltin(IV) complexes of 2-hydroxyhippuric acid.

Journal: Journal of inorganic biochemistry 20010115

Title: Discovery of HIV-1 integrase inhibitors by pharmacophore searching.

Journal: Journal of medicinal chemistry 19970314

Title: [Effect of human serum albumin on transport of drugs through human erythrocyte membranes].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 19960801

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Additional Info:
SDS
Tags:487-54-7 Molecular Formula|487-54-7 MDL|487-54-7 SMILES|487-54-7 2-Hydroxyhippuric acid
Catalog No.: AA00I8Q7
487-54-7,MFCD00002695
487-54-7 | 2-Hydroxyhippuric acid
Pack Size: 10mg
Purity: 97%
in stock
$43.00 $30.00
Pack Size: 1g
Purity: 95%
in stock
$87.00 $61.00
Pack Size: 5g
Purity: 95%
in stock
$278.00 $195.00
Pack Size: 10g
Purity: 95%
in stock
$427.00 $299.00
Pack Size: 25g
Purity: 95%
in stock
$843.00 $590.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00I8Q7
Chemical Name: 2-Hydroxyhippuric acid
CAS Number: 487-54-7
Molecular Formula: C9H9NO4
Molecular Weight: 195.1721
MDL Number: MFCD00002695
SMILES: OC(=O)CNC(=O)c1ccccc1O
Properties
Complexity: 229  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 14  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 3  
XLogP3: 0.9  
Downstream Synthesis Route
56-40-6    1441-87-8    487-54-7 

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Moss;Urist;Martin[ArchivesofBiochemistry,1948,vol.19,p.213,214]

487-54-7    56145-95-0 

[1]Mazzotta;Giori;Guarneri;Benassi[Farmaco,EdizioneScientifica,1975,vol.30,#5,p.399-407]

487-54-7    108-24-7    99-61-6    16352-91-3 

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Gandhi,S.K.etal.[MonatsheftefurChemie,1967,vol.98,#5,p.1751-1753]

487-54-7    108-24-7    120-14-9    16352-92-4 

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Gandhi,S.K.etal.[MonatsheftefurChemie,1967,vol.98,#5,p.1751-1753]

487-54-7    108-24-7    100-10-7    16352-93-5 

[1]Aparna;Sharada;Subhashini;Sreekanth,Sivan[RussianJournalofGeneralChemistry,2019,vol.89,#6,p.1202-1208][Zh.Obshch.Khim.,2019,vol.89,#6,p.1202-1208,7]

[2]Gandhi,S.K.etal.[MonatsheftefurChemie,1967,vol.98,#5,p.1751-1753]

Literature fold

Title: Aspirin metabolites are GPR35 agonists.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20120701

Title: Salicylamide and salicylglycine oxidovanadium complexes with insulin-mimetic properties.

Journal: Journal of inorganic biochemistry20111201

Title: Metabonomic analysis of hepatitis E patients shows deregulated metabolic cycles and abnormalities in amino acid metabolism.

Journal: Journal of viral hepatitis20111001

Title: Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases.

Journal: Journal of nutrigenetics and nutrigenomics20110701

Title: Antiplatelet combinations for prevention of atherothrombotic events.

Journal: Vascular health and risk management20110101

Title: Drug structure-transport relationships.

Journal: Journal of pharmacokinetics and pharmacodynamics20101201

Title: Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor.

Journal: Bioorganic & medicinal chemistry letters20101015

Title: Oral administration of ethanol with aspirin increases the concentration of salicylic acid in plasma and organs, especially the brain, in mice.

Journal: European journal of pharmacology20100610

Title: Terbium-macrocycle complexes as chemical sensors: detection of an aspirin metabolite in urine using a salicylurate-specific receptor site.

Journal: Inorganic chemistry20100517

Title: Quantitative analysis of clopidogrel bisulphate and aspirin by first derivative spectrophotometric method in tablets.

Journal: Indian journal of pharmaceutical sciences20100101

Title: Serum albumin complexation of acetylsalicylic acid metabolites.

Journal: Current drug metabolism20090601

Title: Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.

Journal: Pharmacology20090101

Title: Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping.

Journal: International journal of nanomedicine20090101

Title: Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid.

Journal: Journal of agricultural and food chemistry20081224

Title: Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).

Journal: Bioorganic & medicinal chemistry20081201

Title: Synthesis of a new seleninic acid anhydride and mechanistic studies into its glutathione peroxidase activity.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany)20080101

Title: Chemometric simultaneous estimation of clopidogrel bisulphate and aspirin from combined dosage form.

Journal: Indian journal of pharmaceutical sciences20080101

Title: [Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs].

Journal: Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology20071001

Title: UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.

Journal: Pharmacogenetics and genomics20070801

Title: Willow leaves' extracts contain anti-tumor agents effective against three cell types.

Journal: PloS one20070101

Title: Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie20070101

Title: Effect of cotreatment of aspirin metabolites on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster.

Journal: Drug and chemical toxicology20060101

Title: Increased salicylate concentrations in urine of human volunteers after consumption of cranberry juice.

Journal: Journal of agricultural and food chemistry20050420

Title: Simultaneous determination of gentisic, salicyluric and salicylic acid in human plasma using solid-phase extraction, liquid chromatography and electrospray ionization mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20041005

Title: Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.

Journal: Environmental toxicology20041001

Title: Pharmacokinetics and metabolic rates of acetyl salicylic acid and its metabolites in an Otomi ethnic group of Mexico.

Journal: Biological & pharmaceutical bulletin20040501

Title: Model complexes with naturally occurring ligands (salicylglycine and imidazol) and the biometals copper and cobalt.

Journal: Journal of inorganic biochemistry20040201

Title: Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases.

Journal: Biopharmaceutics & drug disposition20040101

Title: Urinary excretion of salicyluric and salicylic acids by non-vegetarians, vegetarians, and patients taking low dose aspirin.

Journal: Journal of clinical pathology20030901

Title: First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine.

Journal: Analytical and bioanalytical chemistry20021001

Title: Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.

Journal: British journal of pharmacology20020101

Title: Identification and determination of salicylic acid and salicyluric acid in urine of people not taking salicylate drugs.

Journal: Annals of clinical biochemistry20020101

Title: Pharmacokinetics of salicin after oral administration of a standardised willow bark extract.

Journal: European journal of clinical pharmacology20010801

Title: Synthesis and evaluation of the analgesic and antiinflammatory activities of O-substituted salicylamides.

Journal: Archives of pharmacal research20010601

Title: Does excretion of secondary metabolites always involve a measurable metabolic cost? Fate of plant antifeedant salicin in common brushtail possum, Trichosurus vulpecula.

Journal: Journal of chemical ecology20010601

Title: Determination of salicylate, gentisic acid and salicyluric acid in human urine by capillary electrophoresis with laser-induced fluorescence detection.

Journal: Journal of chromatography. B, Biomedical sciences and applications20010305

Title: Potentiometric and spectroscopic studies on the dimethyltin(IV) complexes of 2-hydroxyhippuric acid.

Journal: Journal of inorganic biochemistry20010115

Title: Discovery of HIV-1 integrase inhibitors by pharmacophore searching.

Journal: Journal of medicinal chemistry19970314

Title: [Effect of human serum albumin on transport of drugs through human erythrocyte membranes].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan19960801

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