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50-34-0,MFCD00050291
Catalog No.:AA00I8U3

50-34-0 | Propantheline bromide

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Purity
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500mg
≥95%
in stock  
$38.00   $26.00
- +
1g
98%
in stock  
$45.00   $32.00
- +
5g
98%
in stock  
$103.00   $73.00
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25g
98%
in stock  
$369.00   $259.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I8U3
Chemical Name:
Propantheline bromide
CAS Number:
50-34-0
Molecular Formula:
C23H30BrNO3
Molecular Weight:
448.3932
MDL Number:
MFCD00050291
SMILES:
O=C(C1c2ccccc2Oc2c1cccc2)OCC[N+](C(C)C)(C(C)C)C.[Br-]
NSC Number:
757294
Properties
Properties
 
Form:
Solid  
MP:
159-161°C  
Refractive Index:
1.6200 (estimate)  
Solubility:
H2O: soluble50mg/mL  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
474  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
7  

Literature

Title: The influence of spasmolytic agents on heart rate variability and gastrointestinal motility in normal horses.

Journal: Research in veterinary science 20121201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Suspected differential interactions of digoxin with imidafenacin and propantheline; some thoughts for introspection.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Response to 'Suspected differential interactions of digoxin with imidafenacin and propantheline; some thoughts for introspection'.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Pharmacokinetics of meloxicam administered as regular and fast dissolving formulations to the rat: influence of gastrointestinal dysfunction on the relative bioavailability of two formulations.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081101

Title: Pharmacological interventions for clozapine-induced hypersalivation.

Journal: Schizophrenia bulletin 20080701

Title: Using the zebrafish lateral line to screen for ototoxicity.

Journal: Journal of the Association for Research in Otolaryngology : JARO 20080601

Title: Cycloheximide and disulfoton are positive in the photoclastogencity assay but do not absorb UV irradiation: another example of pseudophotoclastogenicity?

Journal: Mutagenesis 20080301

Title: Clomipramine-induced mood and perceived performance changes in selected healthy individuals.

Journal: Journal of clinical psychopharmacology 20070601

Title: The effectiveness of intravesical oxybutynin, propantheline, and capsaicin in the management of neuropathic bladder following spinal cord injury.

Journal: TheScientificWorldJournal 20070101

Title: Prophylaxis of mucosal toxicity by oral propantheline and cryotherapy in children with malignancies undergoing myeloablative chemo-radiotherapy.

Journal: The Tohoku journal of experimental medicine 20061201

Title: Masking mechanisms of bitter taste of drugs studied with ion selective electrodes.

Journal: Chemical & pharmaceutical bulletin 20060801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Propantheline and in vitro reactivity of urinary bladder smooth muscle in guinea pigs.

Journal: Bratislavske lekarske listy 20050101

Title: Identification and prediction of promiscuous aggregating inhibitors among known drugs.

Journal: Journal of medicinal chemistry 20031009

Title: Taurine in submandibular gland of the rat: effect of muscarinic drugs.

Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020401

Title: An improved method of evaluation of drug-evoked changes in gastric emptying in mice.

Journal: Journal of pharmacological and toxicological methods 20020101

Title: [Protein-losing syndrome of the gastrointestinal tract].

Journal: Deutsche medizinische Wochenschrift (1946) 20011026

Title: A stability-indicating proton nuclear magnetic resonance spectroscopic method for the analysis of propantheline bromide in pharmaceutical samples.

Journal: Die Pharmazie 20010901

Title: Stoichiometric and microenvironmental effects on hydrolysis of propantheline and oxyphenonium bromides in cyclodextrin solutions.

Journal: Journal of pharmaceutical sciences 20010601

Title: Swallow syncope.

Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19860801

Title: Comparison of the effectiveness of ranitidine and cimetidine in inhibiting acid secretion in patients with gastric hypersecretory states.

Journal: The American journal of medicine 19841119

Title: Biopharmaceutic factors that influence effects of anticholinergic drugs: comparison of propantheline, hexocyclium, and isopropamide.

Journal: Journal of pharmaceutical sciences 19771001

Title: Blood levels and management of lithium treatment.

Journal: British medical journal 19740914

Title: J Mokry, et al. Propantheline and in vitro reactivity of urinary bladder smooth muscle in guinea pigs. Bratisl Lek Listy. 2005;106(4-5):151-4.

Title: Richard Jewell, et al. Propantheline. xPharm: The Comprehensive Pharmacology Reference. 2007, Pages 1-5.

Title: S Kobayashi, et al. Effects of YM905, a novel muscarinic M3-receptor antagonist, on experimental models of bowel dysfunction in vivo. Jpn J Pharmacol. 2001 Jul;86(3):281-8.

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