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506-37-6,MFCD00010507
Catalog No.:AA00I90E

506-37-6 | Nervonic acid

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100mg
≥95%
in stock  
$63.00   $44.00
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250mg
≥95%
in stock  
$132.00   $92.00
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500mg
≥95%
in stock  
$216.00   $151.00
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10g
≥95.0%(GC)
in stock  
$3,961.00   $2,773.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I90E
Chemical Name:
Nervonic acid
CAS Number:
506-37-6
Molecular Formula:
C24H46O2
Molecular Weight:
366.6208
MDL Number:
MFCD00010507
SMILES:
CCCCCCCC/C=C\CCCCCCCCCCCCCC(=O)O
Properties
Properties
 
BP:
459.84°C (rough estimate)  
Form:
Liquid  
MP:
42-43 °C(lit.)  
Refractive Index:
1.4806 (estimate)  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
309  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
21  
XLogP3:
9.8  

Downstream Synthesis Route

[1]ThejournaloftheSocietyofChemicalIndustry,Japan.Supplementalbinding.,vol.30,p.229B    ChemischesZentralblatt,1928,vol.99,p.1385

[1]Carroll[CanadianJournalofChemistry,1957,vol.35,p.757]

[2]CurrentPatentAssignee:NORTHWESTA&FUNIVERSITY-CN111423320,2020,A

[1]CanadianJournalofChemistry,1957,vol.35,p.757

506-37-6    86516-36-1   
C40H65N3O3S 

[1]Jiang,Ruiqi;Jiao,Yu;Zhang,Pei;Liu,Yong;Wang,Xu;Huang,Yin;Zhang,Zunjian;Xu,Fengguo[AnalyticalChemistry,2017,vol.89,#22,p.12223-12230]

Literature

Title: Nervonoylceramide (C24:1Cer), a lipid biomarker for ocular irritants released from the 3D reconstructed human cornea-like epithelium, MCTT HCE™.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180301

Title: Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.

Journal: Scientific reports 20180101

Title: Plasma fatty acids in chronic kidney disease: nervonic acid predicts mortality.

Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120301

Title: Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain.

Journal: Neuroscience 20120127

Title: Synthesis and characterization of poly(3-hydroxyalkanoates) from Brassica carinata oil with high content of erucic acid and from very long chain fatty acids.

Journal: International journal of biological macromolecules 20110101

Title: Reduced levels of placental long chain polyunsaturated fatty acids in preterm deliveries.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20110101

Title: An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

Journal: Journal of natural products 20100723

Title: Reversal of mouse Acyl-CoA oxidase 1 (ACOX1) null phenotype by human ACOX1b isoform [corrected].

Journal: Laboratory investigation; a journal of technical methods and pathology 20100501

Title: Molecular cloning and characterization of a KCS gene from Cardamine graeca and its heterologous expression in Brassica oilseeds to engineer high nervonic acid oils for potential medical and industrial use.

Journal: Plant biotechnology journal 20091201

Title: Study of the inhibitory effect of fatty acids on the interaction between DNA and polymerase beta.

Journal: Biochemistry. Biokhimiia 20090701

Title: Increase in nervonic acid content in transformed yeast and transgenic plants by introduction of a Lunaria annua L. 3-ketoacyl-CoA synthase (KCS) gene.

Journal: Plant molecular biology 20090301

Title: Lipophilic components of different therapeutic mud species.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20071201

Title: Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta.

Journal: Biochemical and biophysical research communications 20061110

Title: Isolation, structure elucidation and in vivo hepatoprotective potential of trans-tetracos-15-enoic acid from Indigofera tinctoria Linn.

Journal: Phytotherapy research : PTR 20061001

Title: Relationships between serum unsaturated fatty acids and coronary risk factors: negative relations between nervonic acid and obesity-related risk factors.

Journal: International heart journal 20051101

Title: Sulfoquinovosylmonoacylglycerol inhibitory mode analysis of rat DNA polymerase beta.

Journal: The FEBS journal 20050901

Title: Association between school performance, breast milk intake and fatty acid profile of serum lipids in ten-year-old cleft children.

Journal: The Journal of craniofacial surgery 20050901

Title: Role of the posterior vacuole in Spraguea lophii (Microsporidia) spore hatching.

Journal: Folia parasitologica 20050501

Title: Dietary patterns and blood fatty acid composition in children with attention-deficit hyperactivity disorder in Taiwan.

Journal: The Journal of nutritional biochemistry 20040801

Title: Catalase in microsporidian spores before and during discharge.

Journal: The Biological bulletin 20031001

Title: In-house validation of an improved sample extraction and clean-up method for GC determination of isomers of nervonic acid in meat products.

Journal: Analytical and bioanalytical chemistry 20030601

Title: Nervonic acid is transferred from the maternal diet to milk and tissues of suckling rat pups.

Journal: The Journal of nutritional biochemistry 20030301

Title: Three-dimensional structural model analysis of the binding site of an inhibitor, nervonic acid, of both DNA polymerase beta and HIV-1 reverse transcriptase.

Journal: Journal of biochemistry 20021101

Title: Peroxisomal fatty acid oxidation and cellular redox.

Journal: Methods in enzymology 20020101

Title: Amminger GP, et al. Decreased nervonic acid levels in erythrocyte membranes predict psychosis in help-seekingultra-high-risk individuals. Mol Psychiatry. 2012 Dec;17(12):1150-2.

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