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50924-49-7,MFCD30181862
Catalog No.:AA00I91X

50924-49-7 | Mizoribine

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1mg
98%
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5mg
98%
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10mg
98%
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25mg
98%(HPLC)
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50mg
98%
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100mg
98%(HPLC)
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$77.00   $54.00
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250mg
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1g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I91X
Chemical Name:
Mizoribine
CAS Number:
50924-49-7
Molecular Formula:
C9H13N3O6
Molecular Weight:
259.2160
MDL Number:
MFCD30181862
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc(c1O)C(=O)N
Properties
Computed Properties
 
Complexity:
329  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
XLogP3:
-1.9  

Literature

Title: Profiling the immunotoxicity of chemicals based on in vitro evaluation by a combination of the Multi-ImmunoTox assay and the IL-8 Luc assay.

Journal: Archives of toxicology 20180601

Title: Efficacy and safety of multitarget therapy with mizoribine and tacrolimus for systemic lupus erythematosus with or without active nephritis.

Journal: Lupus 20121101

Title: Population pharmacokinetics of mizoribine in pediatric recipients of renal transplantation.

Journal: Clinical and experimental nephrology 20121001

Title: Mizoribine, tacrolimus, and corticosteroid combination therapy successfully induces remission in patients with lupus nephritis.

Journal: Clinical and experimental nephrology 20121001

Title: Effect of single-dose oral mizoribine pulse therapy twice per week for frequently relapsing steroid-dependent nephrotic syndrome.

Journal: Clinical nephrology 20120701

Title: Childhood nephrotic syndrome--current and future therapies.

Journal: Nature reviews. Nephrology 20120612

Title: Pharmacokinetics of mizoribine in adult living donor liver transplantation.

Journal: Transplantation proceedings 20120601

Title: Addition of mizoribine to the prednisolone plus tacrolimus treatment regimen in a patient with lupus flare.

Journal: Rheumatology international 20120401

Title: GSTT1 gene abnormality in minimal change nephrotic syndrome with elevated serum immunoglobulin E.

Journal: Clinical nephrology 20120401

Title: Mizoribine--an inosine monophosphate dehydrogenase inhibitor--acts synergistically with cyclosporine A in prolonging survival of murine islet cell and heart transplants across major histocompatibility barrier.

Journal: Transplant immunology 20120301

Title: Final height in a prospective trial of late steroid withdrawal after pediatric renal transplantation treated with cyclosporine and mizoribine.

Journal: Pediatric transplantation 20120201

Title: Developmental disruption of the serotonin system alters circadian rhythms.

Journal: Physiology & behavior 20120118

Title: The efficacy and safety of high-dose mizoribine in ABO-incompatible kidney transplantation using anti-CD20 and anti-CD25 antibody without splenectomy treatment.

Journal: Transplantation proceedings 20120101

Title: Excellent results with high-dose mizoribine combined with cyclosporine, corticosteroid, and basiliximab in renal transplant recipients: multicenter study in Japan.

Journal: Transplantation proceedings 20120101

Title: Experiences of high-dose mizoribine as antimetabolite immunosuppressants for kidney transplantation.

Journal: Transplantation proceedings 20120101

Title: Mizoribine suppresses proliferation of rat glomerular epithelial cells in culture and inhibits increase of monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 stimulated by thrombin.

Journal: Biological & pharmaceutical bulletin 20120101

Title: A case of acute kidney injury with marked hyperuricemia during mizoribine administration.

Journal: Internal medicine (Tokyo, Japan) 20120101

Title: Mizoribine as sole immunosuppressive agent in islet xenotransplantation models: a candidate immunosuppressant causing no adverse effects on islets.

Journal: Cell transplantation 20120101

Title: Mizoribine treatment for antihistamine-resistant chronic autoimmune urticaria.

Journal: Dermatologic therapy 20120101

Title: Therapeutic effect of mizoribine on pemphigus vulgaris and pemphigus foliaceus.

Journal: Dermatologic therapy 20120101

Title: Chronopharmacology of mizoribine in collagen-induced arthritis rats.

Journal: Journal of pharmacological sciences 20120101

Title: [Therapy in IgA nephropathy--when and how to do it].

Journal: Orvosi hetilap 20111218

Title: Population pharmacokinetics of mizoribine in adult recipients of renal transplantation.

Journal: Clinical and experimental nephrology 20111201

Title: Structures of Burkholderia thailandensis nucleoside kinase: implications for the catalytic mechanism and nucleoside selectivity.

Journal: Acta crystallographica. Section D, Biological crystallography 20111101

Title: [Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 5. Leflunomide and mizoribine].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20111010

Title: Successful use of mizoribine in a patient with sarcoidosis and cutaneous vasculitis.

Journal: Acta dermato-venereologica 20110901

Title: Novel multidrug therapy for children with cyclosporine-resistant or -intolerant nephrotic syndrome.

Journal: Pediatric nephrology (Berlin, Germany) 20110801

Title: Enzymatic assay method for measuring mizoribine levels in serum.

Journal: Journal of bioscience and bioengineering 20110801

Title: Use of mizoribine in two patients with recalcitrant cutaneous polyarteritis nodosa.

Journal: Journal of the American Academy of Dermatology 20110601

Title: Efficacy and safety of mizoribine combined with losartan in the treatment of IgA nephropathy: a multicenter, randomized, controlled study.

Journal: The American journal of the medical sciences 20110501

Title: Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20110501

Title: Methylprednisolone pulse plus mizoribine in children with Henoch-Schoenlein purpura nephritis.

Journal: Clinical rheumatology 20110401

Title: Steroid treatment in patients with membranous nephropathy and hepatitis B virus surface antigenemia: a report of two cases.

Journal: Clinical and experimental nephrology 20110401

Title: Therapeutic efficacy of mizoribine for discoid lupus erythematosus with normalized frequency of circulating T helper 17 cells.

Journal: Clinical and experimental dermatology 20110401

Title: Single daily high-dose mizoribine therapy for children with steroid-dependent nephrotic syndrome prior to cyclosporine administration.

Journal: Pediatric nephrology (Berlin, Germany) 20110301

Title: Modulation in concentrative nucleoside transporters-mediated intestinal absorption of mizoribine, an immunosuppressive agent, in lipopolysaccharide-treated rats.

Journal: Die Pharmazie 20110301

Title: Methylprednisolone pulse therapy combined with mizoribine following tonsillectomy for immunoglobulin A nephropathy: clinical remission rate, steroid sparing effect, and maintenance of renal function.

Journal: Clinical and experimental nephrology 20110201

Title: Disappearance of glomerular IgA deposits in childhood IgA nephropathy showing diffuse mesangial proliferation after 2 years of combination/prednisolone therapy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101

Title: Evaluation of limited sampling designs to estimate maximal concentration and area under the curve of mizoribine in pediatric patients with renal disease.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: [Two cases of rapidly progressive nephritic syndrome complicated with alcoholic liver cirrhosis].

Journal: Nihon Jinzo Gakkai shi 20110101

Title: Cardiac AA amyloidosis in a patient with rheumatoid arthritis and systemic sclerosis: the therapeutic potential of biological reagents.

Journal: Scandinavian journal of rheumatology 20110101

Title: [Efficacy and safety of combination therapy with mizoribine and methotrexate for rheumatoid arthritis resistant with methotrexate].

Journal: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20110101

Title: Effect of genetic polymorphisms of SLC28A1, ABCG2, and ABCC4 on bioavailability of mizoribine in healthy Japanese males.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: [Secondary membranous nephropathy: The topics of membranous lupus nephritis].

Journal: Nihon Jinzo Gakkai shi 20110101

Title: Successful treatment of chronic lupus myocarditis with prednisolone and mizoribine.

Journal: Modern rheumatology 20101201

Title: Low-dose steroid maintenance for renal transplant recipients.

Journal: Transplantation proceedings 20101201

Title: Effects of probenecid on the pharmacokinetics of mizoribine and co-administration of the two drugs in patients with nephrotic syndrome.

Journal: International journal of clinical pharmacology and therapeutics 20101101

Title: Mizoribine protects against bleomycin-induced lung injury.

Journal: Modern rheumatology 20101001

Title: Modelling the effects of inhibitors of guanine nucleotide synthesis: implications for studies of cellular differentiation pathways.

Journal: Biochemical Society transactions 20101001

Title: Efficacy of mizoribine for steroid-resistant membranoproliferative glomerulonephritis type III.

Journal: Nephrology (Carlton, Vic.) 20101001

Title: Mizoribine attenuates renal injury and macrophage infiltration in patients with severe lupus nephritis.

Journal: Clinical rheumatology 20100901

Title: Acute allograft renal failure with marked hyperuricemia developing during mizoribine administration: a case report with review of the literature.

Journal: Transplantation proceedings 20100901

Title: A sensitive and practical LC-MS/MS method for the determination of mizoribine in human serum and its bioequivalence study on Chinese healthy volunteers.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20100901

Title: Increased intestinal absorption of mizoribine, an immunosuppressive agent, in cholestatic rats.

Journal: Die Pharmazie 20100701

Title: Mizoribine therapy in a patient with lupus nephritis: the association between mizoribine concentration and peritoneal dialysis.

Journal: Modern rheumatology 20100601

Title: Novel anticytomegalovirus activity of immunosuppressant mizoribine and its synergism with ganciclovir.

Journal: The Journal of pharmacology and experimental therapeutics 20100601

Title: Combination therapy with steroids and mizoribine in juvenile SLE: a randomized controlled trial.

Journal: Pediatric nephrology (Berlin, Germany) 20100501

Title: Impact of concentrative nucleoside transporter 1 gene polymorphism on oral bioavailability of mizoribine in stable kidney transplant recipients.

Journal: Basic & clinical pharmacology & toxicology 20100401

Title: Mizoribine reduces serum KL-6 levels in ANCA-associated vasculitis.

Journal: Clinical and experimental nephrology 20100401

Title: Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats.

Journal: European journal of pharmacology 20100225

Title: Successful use of mizoribine to treat recurrent corticosteroid-resistant palpable purpura in a patient with henoch-schonlein purpura nephritis.

Journal: Archives of dermatology 20100201

Title: Effect of mizoribine in children with inflammatory bowel disease.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20100201

Title: New algorithm (KAWAKAMI algorithm) to diagnose primary cutaneous vasculitis.

Journal: The Journal of dermatology 20100201

Title: Contrasting effects of steroids and mizoribine on macrophage activation and glomerular lesions in rat thy-1 mesangial proliferative glomerulonephritis.

Journal: American journal of nephrology 20100101

Title: Combinational effect of low-dose oral corticosteroid and mizoribine for ulcerative colitis in a patient with systemic sclerosis.

Journal: The Journal of dermatology 20100101

Title: The immunosuppressive drug mizoribine directly prevents podocyte injury in puromycin aminonucleoside nephrosis.

Journal: Nephron. Experimental nephrology 20100101

Title: Treatment of Mikulicz's disease with mizoribine.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: A case of Mikulicz's disease, IgG4-related plasmacytic syndrome, successfully treated by corticosteroid and mizoribine, followed by mizoribine alone.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: A novel target of mizoribine inhibiting mesangial cell proliferation: S phase kinase-associated protein 2.

Journal: American journal of nephrology 20100101

Title: Efficacy and safety of mizoribine by one single dose administration for patients with rheumatoid arthritis.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: [Minimal change nephrotic syndrome].

Journal: Nihon Jinzo Gakkai shi 20100101

Title: [Focal segmental glomerulosclerosis (FSGS)].

Journal: Nihon Jinzo Gakkai shi 20100101

Title: [Immunosuppressive therapies for refractory nephrotic syndrome].

Journal: Nihon Jinzo Gakkai shi 20100101

Title: Protective effects of Mizoribine on Cyclosporine A nephropathy in rats.

Journal: Pediatric research 20091101

Title: Usefulness of initial histological features for stratifying Sjogren's syndrome responders to mizoribine therapy.

Journal: Rheumatology (Oxford, England) 20091001

Title: Remission of refractory minimal change nephrotic syndrome after basiliximab therapy.

Journal: Pediatric nephrology (Berlin, Germany) 20090701

Title: Iliopectineal bursitis associated with rapid destruction of a rheumatoid hip joint.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20090701

Title: Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab.

Journal: Modern rheumatology 20090601

Title: Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells.

Journal: Biological & pharmaceutical bulletin 20090401

Title: Mizoribine may suppress bone erosion in patients with rheumatoid arthritis by inhibiting osteoclastogenesis.

Journal: European journal of pharmacology 20090301

Title: Therapeutic effect of mizoribine on bullous pemphigoid associated with membranous nephropathy.

Journal: Journal of the American Academy of Dermatology 20090301

Title: [Renal involvement in connective tissue diseases].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20090301

Title: [Immunosuppressants].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20090301

Title: Mizoribine for renal sarcoidosis: effective steroid tapering and prevention of recurrence.

Journal: Pediatric nephrology (Berlin, Germany) 20090201

Title: Successful treatment of refractory polymyositis with the immunosuppressant mizoribine: case report.

Journal: Clinical rheumatology 20090201

Title: A case report of steroid-resistant antineutrophil cytoplasmic antibody-related vasculitis successfully treated by mizoribine in a hemodialysis patient.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20090201

Title: [ANCA associated vasculitis and PRGN].

Journal: Nihon Jinzo Gakkai shi 20090101

Title: Mizoribine suppresses the progression of experimental peritoneal fibrosis in a rat model.

Journal: Nephron. Experimental nephrology 20090101

Title: Effects of low-dose mizoribine pulse therapy in combination with methotrexate in rheumatoid arthritis patients with an insufficient response to methotrexate.

Journal: Modern rheumatology 20090101

Title: Mizoribine: a new approach in the treatment of renal disease.

Journal: Clinical & developmental immunology 20090101

Title: A simple HPLC method for the quantification of mizoribine in human serum: pharmacokinetic applications.

Journal: Biomedical chromatography : BMC 20081101

Title: Mizoribine for relapsed proteinuria in an adult IgA nephropathy patient.

Journal: Clinical nephrology 20081101

Title: A novel enzymatic method for measuring mizoribine 5'-monophosphate levels in serum.

Journal: Journal of bioscience and bioengineering 20081101

Title: Pharmacokinetic study of mizoribine in child-onset glomerulonephritis.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20081001

Title: Hypocomplementemic urticarial vasculitis with Jaccoud's arthropathy and valvular heart disease: case report and review of the literature.

Journal: Lupus 20080901

Title: Conversion from mycophenolate mofetil to mizoribine for patients with positive polyomavirus type BK in urine.

Journal: Transplantation proceedings 20080901

Title: Oral mizoribine pulse therapy for steroid-dependent focal segmental glomerulosclerosis.

Journal: Clinical nephrology 20080601

Title: Characterization of intestinal absorption of mizoribine mediated by concentrative nucleoside transporters in rats.

Journal: European journal of pharmacology 20080531

Title: Combination therapy with mizoribine for severe childhood IgA nephropathy: a pilot study.

Journal: Pediatric nephrology (Berlin, Germany) 20080501

Title: Use of mizoribine as a rescue drug for steroid-resistant pediatric IgA nephropathy.

Journal: Pediatric nephrology (Berlin, Germany) 20080401

Title: Effect of oral mizoribine pulse therapy for frequently relapsing steroid-dependent nephrotic syndrome.

Journal: Clinical nephrology 20080301

Title: Non-corticosteroid treatment for nephrotic syndrome in children.

Journal: The Cochrane database of systematic reviews 20080123

Title: Mizoribine intermittent pulse protocol for induction therapy for systemic lupus erythematosus in children: an open-label pilot study with five newly diagnosed patients.

Journal: Clinical rheumatology 20080101

Title: A case of lupus nephritis improved after appropriately adjusting the dosage of mizoribine.

Journal: Modern rheumatology 20080101

Title: [Treatment of childhood IgA nephropathy].

Journal: Nihon Jinzo Gakkai shi 20080101

Title: A sudden onset of diabetic ketoacidosis and acute pancreatitis after introduction of mizoribine therapy in a patient with rheumatoid arthritis.

Journal: Modern rheumatology 20080101

Title: Mizoribine treatment of young patients with severe lupus nephritis: a clinicopathologic study by the tohoku pediatric study group.

Journal: Nephron. Clinical practice 20080101

Title: Japanese experience of ABO-incompatible living kidney transplantation.

Journal: Transplantation 20071227

Title: Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis.

Journal: Fungal genetics and biology : FG & B 20071201

Title: Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus.

Journal: Chemistry & biology 20071001

Title: Mizoribine corrects defective nephrin biogenesis by restoring intracellular energy balance.

Journal: Journal of the American Society of Nephrology : JASN 20070901

Title: Efficacy of steroid pulse, plasmapheresis, and mizoribine in a patient with focal segmental glomerulosclerosis.

Journal: Pediatric nephrology (Berlin, Germany) 20070801

Title: Long-term intermittent pulse therapy with mizoribine attenuates histologic progression in young patients with severe lupus nephritis: report of two patients.

Journal: Nephrology (Carlton, Vic.) 20070801

Title: Combination therapy of prednisolone and mizoribine improves cryoglobulinemic vasculitis with purpura and skin ulcers.

Journal: Clinical rheumatology 20070701

Title: Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents.

Journal: Bioorganic & medicinal chemistry letters 20070501

Title: Safety, tolerability and pharmacokinetics of higher-dose mizoribine in healthy male volunteers.

Journal: British journal of clinical pharmacology 20070401

Title: Prophylactic treatment of antibody-mediated rejection with high-dose mizoribine and pharmacokinetic study.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070401

Title: Efficacy of single dose of oral mizoribine pulse therapy two times per week for frequently relapsing nephrotic syndrome.

Journal: Journal of nephrology 20070101

Title: Mizoribine therapy for patients with lupus nephritis: the association between peak mizoribine concentration and clinical efficacy.

Journal: Modern rheumatology 20070101

Title: Efficacy and safety of mizoribine for the treatment of Sjögren's syndrome: a multicenter open-label clinical trial.

Journal: Modern rheumatology 20070101

Title: Population pharmacokinetics of higher-dose mizoribine in healthy male volunteers.

Journal: Biological & pharmaceutical bulletin 20061201

Title: Mizoribine oral pulse therapy for a patient with polyarticular juvenile idiopathic arthritis.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20061201

Title: Effects of mizoribine on MHC-restricted exogenous antigen presentation in dendritic cells.

Journal: Archives of pharmacal research 20061201

Title: Comparison of tacrolimus and mizoribine in a randomized, double-blind controlled study in patients with rheumatoid arthritis.

Journal: The Journal of rheumatology 20061101

Title: Changing mizoribine administration from three divided doses to one single dose induced remission of relapsed membranous nephropathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801

Title: Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin.

Journal: Antiviral research 20060801

Title: Combination effect of mycophenolate mofetil with mizoribine on cell proliferation assays and in a mouse heart transplantation model.

Journal: Transplantation 20060727

Title: Long-term mizoribine intermittent pulse therapy for young patients with flare of lupus nephritis.

Journal: Pediatric nephrology (Berlin, Germany) 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Mizoribine induces remission of relapsed ANCA-associated renal vasculitis.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060401

Title: High-dose mizoribine treatment for adolescents with systemic lupus erythematosus.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20060401

Title: The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats.

Journal: European journal of pharmacology 20060215

Title: [Molecular action mechanisms of the therapeutic agents for kidney diseases: Immunosuppressants].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060201

Title: Stevens-Johnson syndrome induced by mizoribine in a patient with systemic lupus erythematosus.

Journal: Modern rheumatology 20060101

Title: [Beneficial and adverse effects of high-dosage MZR therapy in the management of children with frequently relapsing nephrotic syndrome].

Journal: Nihon Jinzo Gakkai shi 20060101

Title: Acceptability and usefulness of mizoribine in the management of rheumatoid arthritis in methotrexate-refractory patients and elderly patients, based on analysis of data from a large-scale observational cohort study.

Journal: Modern rheumatology 20060101

Title: Revival of effective and safe high-dose mizoribine for the kidney transplantation.

Journal: Clinical transplantation 20060101

Title: High-dose mizoribine therapy for childhood-onset frequently relapsing steroid-dependent nephrotic syndrome with cyclosporin nephrotoxicity.

Journal: Pediatric nephrology (Berlin, Germany) 20051201

Title: Induction therapy with low-dose intravenous cyclophosphamide, oral mizoribine, and steroids for severe lupus nephritis in children.

Journal: Pediatric nephrology (Berlin, Germany) 20051001

Title: Oral mizoribine pulse therapy for patients with steroid-resistant and frequently relapsing steroid-dependent nephrotic syndrome.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051001

Title: Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801

Title: Effects of long-term treatment with mizoribine in patients with proliferative lupus nephritis.

Journal: Clinical nephrology 20050701

Title: Mizoribine decreases urinary protein excretion in two patients with IgA nephropathy.

Journal: Clinical nephrology 20050701

Title: Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus.

Journal: Antiviral research 20050601

Title: Implication of the peak serum level of mizoribine for control of the serum anti-dsDNA antibody titer in patients with lupus nephritis.

Journal: Clinical nephrology 20050601

Title: Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha.

Journal: Biochemical and biophysical research communications 20050513

Title: Immunosuppressive efficacy of mycophenolate mofetil when compared with azathioprine and mizoribine against peripheral lymphocytes from renal transplant recipients.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050501

Title: [Mizoribine].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050501

Title: Potential value of high-dose mizoribine as rescue therapy for ongoing acute humoral rejection.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050401

Title: A prospective trial of steroid withdrawal after renal transplantation treated with cyclosporine and mizoribine in children: results obtained between 1990 and 2003.

Journal: Pediatric transplantation 20050401

Title: Mizoribine-induced rhabdomyolysis in a rheumatoid arthritis patient receiving bezafibrate treatment.

Journal: The American journal of the medical sciences 20050401

Title: The functional basis of mycophenolic acid resistance in Candida albicans IMP dehydrogenase.

Journal: The Journal of biological chemistry 20050325

Title: Mizoribine in combination therapy with tacrolimus for living donor renal transplantation: analysis of a nationwide study in Japan.

Journal: Transplantation proceedings 20050301

Title: Mizoribine oral pulse therapy for steroid-dependent nephrotic syndrome.

Journal: Pediatric nephrology (Berlin, Germany) 20050101

Title: Mizoribine pulse therapy for a pediatric patient with steroid-resistant nephrotic syndrome.

Journal: The Tohoku journal of experimental medicine 20050101

Title: Mizoribine-mediated apoptotic signaling pathway in human T-Cell line.

Journal: Transplantation proceedings 20050101

Title: A simple determination of mizoribine in human plasma by liquid chromatography with UV detection.

Journal: Journal of AOAC International 20050101

Title: [Treatment guidelines for the idiopathic nephrotic syndrome in children].

Journal: Nihon Jinzo Gakkai shi 20050101

Title: Inhibition of bovine viral diarrhea virus (BVDV) by mizoribine: synergistic effect of combination with interferon-alpha.

Journal: Antiviral research 20041201

Title: Mizoribine for the treatment of lupus nephritis in children and adolescents.

Journal: Clinical nephrology 20041201

Title: Pharmacokinetic study of mizoribine in an adolescent with lupus nephritis.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20041001

Title: [Immunosuppressive therapy for nephrotic syndrome and strategy for adverse side effects from that therapy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20041001

Title: Efficacy of mizoribine in the treatment of systemic lupus erythematosus in children.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20040801

Title: Mizoribine pulse therapy for patients with flares of lupus nephritis: a 1-year observation.

Journal: Clinical nephrology 20040801

Title: Treatment with the purine synthesis inhibitor mizoribine for ANCA-associated renal vasculitis.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20040701

Title: [Angiotensin type 1 receptor blocker reduced proteinuria in patients of focal glomerular sclerosis].

Journal: Nihon Jinzo Gakkai shi 20040701

Title: D-penicillamine-induced pemphigus successfully treated with combination therapy of mizoribine and prednisolone.

Journal: The Journal of dermatological treatment 20040701

Title: A randomized open-label comparative study of conventional therapy versus mizoribine onlay therapy in patients with steroid-resistant nephrotic syndrome (postmarketing survey).

Journal: Clinical and experimental nephrology 20040601

Title: [A case of rheumatoid arthritis/Sjogren's syndrome with acute renal failure due to hyperuricemia associated with mizoribine therapy].

Journal: Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20040601

Title: Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.

Journal: Biochemistry 20040420

Title: Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.

Journal: Current medicinal chemistry 20040401

Title: A prospective trial of steroid withdrawal after renal transplantation in children: results obtained 1990 and 2002.

Journal: Transplantation proceedings 20040301

Title: Efficacy of prednisolone and mizoribine therapy for diffuse IgA nephropathy.

Journal: American journal of nephrology 20040101

Title: Allochronic overlapping malignancies after renal transplantation in a patient with p53 gene mutation: report of a case.

Journal: Surgery today 20040101

Title: Efficacy of multidrug therapy combined with mizoribine in children with diffuse IgA nephropathy in comparison with multidrug therapy without mizoribine and with methylprednisolone pulse therapy.

Journal: American journal of nephrology 20040101

Title: Mizoribine oral pulse therapy for patients with disease flare of lupus nephritis.

Journal: Clinical nephrology 20031201

Title: Comparison of antiproteinuric effects of two different combination therapies in children with IgA nephropathy.

Journal: Clinical and experimental nephrology 20031201

Title: Mizoribine oral pulse therapy for a patient with severe lupus nephritis.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20030801

Title: The immunosuppressive agent mizoribine monophosphate forms a transition state analogue complex with inosine monophosphate dehydrogenase.

Journal: Biochemistry 20030204

Title: [IMP dehydrogenase].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030101

Title: Effect of conversion from cyclosporine A to mizoribine on transplant arteriosclerosis in rat aortic allograft models.

Journal: Microsurgery 20030101

Title: Metabolic enzymes as targets for 14-3-3 proteins.

Journal: Plant molecular biology 20021201

Title: Acute vascular and interstitial rejection following renal allograft transplantation in dogs.

Journal: The Journal of veterinary medical science 20021201

Title: [Guidelines for the management of refractory nephrotic syndrome--from investigations between 1997 and 2001--research project team for progressive renal lesions in the Ministry of Health, Labor and Welfare, Japan].

Journal: Nihon Jinzo Gakkai shi 20021201

Title: Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.

Journal: Antiviral chemistry & chemotherapy 20021101

Title: [A case of acute renal failure with marked hyperuricemia developing during mizoribine administration].

Journal: Nihon Jinzo Gakkai shi 20021001

Title: Synergistic effect of high-dose mizoribine and low-dose tacrolimus on renal allograft survival in nonhuman primates.

Journal: Transplantation proceedings 20020801

Title: Reversible segmental stenotic lesion of subclavian artery in an 8-year-old girl: an atypical Takayasu's arteritis?

Journal: Clinical rheumatology 20020801

Title: Effect of mizoribine on IL-6 release by peripheral blood mononuclear cells.

Journal: Nephron 20020701

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Mizoribine: mode of action and effects in clinical use.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20020401

Title: Mizoribine as an effective combined maintenance therapy with prednisolone in child-onset systemic lupus erythematosus.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20020401

Title: Nephrotic syndrome and mizoribine in children.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20020401

Title: Mizoribine treatment for childhood IgA nephropathy.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20020401

Title: Role of mizoribine in renal transplantation.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20020401

Title: Identification of heat shock protein 60 as a molecular mediator of alpha 3 beta 1 integrin activation.

Journal: Cancer research 20020301

Title: Potentiating effect of mizoribine on the anti-herpes virus activity of acyclovir.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Title: Mizoribine ameliorates the tubulointerstitial fibrosis of obstructive nephropathy.

Journal: Nephron 20011001

Title: [Systemic lupus erythematosus presenting as a brainstem infarction and hemorrhage during treating retroperitoneal abscess: a case report].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20010701

Title: Effect of mizoribine on serum IgE concentration in patients with IgA nephropathy.

Journal: Nephron 20010201

Title: The antiproliferative effect of mizoribine on rheumatoid synovial fibroblast mediated by induction of apoptosis.

Journal: The Kobe journal of medical sciences 20010201

Title: Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells.

Journal: Endocrinology 20010101

Title: The efficacy and safety of mizoribine in living donor kidney transplantation: a 24-week, open-label, prospective study (phase III clinical trial).

Journal: Transplantation proceedings 20010101

Title: Long-term results of spousal renal donor transplants with donor-specific blood transfusions.

Journal: Transplantation proceedings 20010101

Title: Dosing time-dependent pharmacological effects of anti-metabolites for rat cardiac graft.

Journal: Research communications in molecular pathology and pharmacology 20010101

Title: Mizoribine in steroid-dependent nephrotic syndrome of childhood.

Journal: Pediatric nephrology (Berlin, Germany) 19971001

Title: Mizoribine reduces urinary protein excretion in rats given puromycin aminonucleoside.

Journal: American journal of nephrology 19960101

Title: [Comparison of the effects of various immunosuppressive drugs on subrenal capsule assay (SRC assay)].

Journal: Hinyokika kiyo. Acta urologica Japonica 19900701

Title: [Suppressive effect of mizoribine on progression of bovine serum albumin nephritis in mice].

Journal: Nihon Jinzo Gakkai shi 19870401

Title: Naka K, et al. Mizoribine inhibits hepatitis C virus RNA replication: effect of combination with interferon-alpha. Biochem Biophys Res Commun. 2005 May 13;330(3):871-9.

Title: Saijo M, et al. Inhibitory effect of Mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus. Antiviral Res. 2005 Jun;66(2-3):159-63.

Title: Kamada H, et al. Effect of Mizoribine on collagen-induced arthritis in mice. Jpn J Pharmacol. 1996 Feb;70(2):169-75.

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