Title: Evodiamine, a plant alkaloid, induces calcium/JNK-mediated autophagy and calcium/mitochondria-mediated apoptosis in human glioblastoma cells.
Journal: Chemico-biological interactions 20130905
Title: Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region.
Journal: The pharmacogenomics journal 20121001
Title: New tricks for an old natural product: discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure-activity relationship analysis and biological evaluations.
Journal: Journal of medicinal chemistry 20120913
Title: Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.
Journal: Fitoterapia 20120701
Title: Evodiamine, a dual catalytic inhibitor of type I and II topoisomerases, exhibits enhanced inhibition against camptothecin resistant cells.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120515
Title: Cytotoxic effect of evodiamine in SGC-7901 human gastric adenocarcinoma cells via simultaneous induction of apoptosis and autophagy.
Journal: Oncology reports 20120501
Title: Pharmacokinetic comparisons of rutaecarpine and evodiamine after oral administration of Wu-Chu-Yu extracts with different purities to rats.
Journal: Journal of ethnopharmacology 20120131
Title: Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells.
Journal: Immunological investigations 20120101
Title: Enhanced antitumor efficacy of gemcitabine by evodiamine on pancreatic cancer via regulating PI3K/Akt pathway.
Journal: International journal of biological sciences 20120101
Title: Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction.
Journal: Journal of Asian natural products research 20120101
Title: In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion.
Journal: International journal of nanomedicine 20120101
Title: A drug screening method based on the autophagy pathway and studies of the mechanism of evodiamine against influenza A virus.
Journal: PloS one 20120101
Title: Binding mode pediction of evodiamine within vanilloid receptor TRPV1.
Journal: International journal of molecular sciences 20120101
Title: Induction of apoptosis by evodiamine involves both activation of mitotic arrest and mitotic slippage.
Journal: Oncology reports 20111201
Title: Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics.
Journal: Die Pharmazie 20111201
Title: [Studies on pharmacokinetics of evodiamine and rutaecarpine in rats plasma after oral administration extracts of euodiae fructus].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20111201
Title: Molecular mechanisms of activation of endothelial nitric oxide synthase mediated by transient receptor potential vanilloid type 1.
Journal: Cardiovascular research 20110801
Title: Evodiamine inhibits 12-O-tetradecanoylphorbol-13-acetate-induced activator protein 1 transactivation and cell transformation in human hepatocytes.
Journal: Phytotherapy research : PTR 20110701
Title: Acid sphingomyelinase contributes to evodiamine-induced apoptosis in human gastric cancer SGC-7901 cells.
Journal: DNA and cell biology 20110601
Title: Inhibitory effects of Zuo-Jin-Wan and its alkaloidal ingredients on activator protein 1, nuclear factor-κB, and cellular transformation in HepG2 cells.
Journal: Fitoterapia 20110601
Title: [Determination of evodiamine and rutacarpine in zhuyu hewei zhitong capsules by HPLC].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110401
Title: Evodiamine improves congnitive abilities in SAMP8 and APP(swe)/PS1(ΔE9) transgenic mouse models of Alzheimer's disease.
Journal: Acta pharmacologica Sinica 20110301
Title: [Optimization of a HPLC determination method for Evodia rutaecarpa].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110201
Title: New strategies in the discovery of novel non-camptothecin topoisomerase I inhibitors.
Journal: Current medicinal chemistry 20110101
Title: Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion.
Journal: International journal of nanomedicine 20110101
Title: [Synthesis, physicochemical and pharmacological properties of pentacyclic alkaloid-analogues].
Journal: Acta pharmaceutica Hungarica 20110101
Title: Optimization of extraction of evodiamine and rutaecarpine from fruit of Evodia rutaecarpa using modified supercritical CO(2).
Journal: Journal of chromatography. A 20101210
Title: Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents.
Journal: Journal of medicinal chemistry 20101111
Title: Evodiamine as a novel antagonist of aryl hydrocarbon receptor.
Journal: Biochemical and biophysical research communications 20101105
Title: Evodiamine induces caspase-dependent apoptosis and S phase arrest in human colon lovo cells.
Journal: Anti-cancer drugs 20100901
Title: Anti-proliferative effects of evodiamine on human thyroid cancer cell line ARO.
Journal: Journal of cellular biochemistry 20100815
Title: Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells.
Journal: Free radical research 20100701
Title: A new quinolone and other constituents from the fruits of Tetradium ruticarpum: effects on neutrophil pro-inflammatory responses.
Journal: Chemistry & biodiversity 20100701
Title: Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation.
Journal: Fitoterapia 20100601
Title: Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20100401
Title: Inhibitory effect of evodiamine alone and in combination with rosiglitazone on in vitro adipocyte differentiation and in vivo obesity related to diabetes.
Journal: International journal of obesity (2005) 20100201
Title: Immobilizing topoisomerase I on a surface plasmon resonance biosensor chip to screen for inhibitors.
Journal: Journal of biomedical science 20100101
Title: Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway.
Journal: FEBS letters 20091119
Title: [Assay of evodin, evodiamine and rutaecarpine in Fructus Evodiae by QAMS].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101
Title: [Determination of evodiamine and rutaecarpine of compound Wuzhuyu cataplasm in plasma by SPE-HPLC: application to its pharmacokinetics].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20091101
Title: Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats.
Journal: Journal of cellular biochemistry 20091001
Title: Evodiamine represses hypoxia-induced inflammatory proteins expression and hypoxia-inducible factor 1alpha accumulation in RAW264.7.
Journal: Shock (Augusta, Ga.) 20090901
Title: Antiproliferation and apoptosis induced by evodiamine in human colorectal carcinoma cells (COLO-205).
Journal: Chemistry & biodiversity 20090601
Title: Evodiamine: a novel anti-cancer alkaloid from Evodia rutaecarpa.
Journal: Molecules (Basel, Switzerland) 20090518
Title: Evodiamine and rutaecarpine inhibit migration by LIGHT via suppression of NADPH oxidase activation.
Journal: Journal of cellular biochemistry 20090501
Title: [Study on vitro release and transdermal behaviors of Yulian cataplasm].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401
Title: Evodiamine stabilizes topoisomerase I-DNA cleavable complex to inhibit topoisomerase I activity.
Journal: Molecules (Basel, Switzerland) 20090327
Title: Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats.
Journal: Brain research 20090109
Title: The permeability and the efflux of alkaloids of the Evodiae fructus in the Caco-2 model.
Journal: Phytotherapy research : PTR 20090101
Title: Enhancement of apoptosis of human hepatocellular carcinoma SMMC-7721 cells through synergy of berberine and evodiamine.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20081201
Title: Immunoregulatory effect of evodiamine in mice of various germlines.
Journal: Zhongguo shi yan xue ye xue za zhi 20080801
Title: Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells.
Journal: Free radical research 20080501
Title: Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: involvement of antiadipogenic mechanism and extracellularly regulated kinase/mitogen-activated protein kinase signaling.
Journal: Endocrinology 20080101
Title: Nitric oxide activated by p38 and NF-kappaB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells.
Journal: Free radical research 20080101
Title: Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis.
Journal: Free radical research 20071001
Title: [Methodological studies on equivalent relationship between granule for clinical prescription and clinical decoction of fructus evodiae].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070601
Title: Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3.
Journal: Journal of cellular biochemistry 20070501
Title: Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells.
Journal: European journal of pharmacology 20070126
Title: In vitro and in vivo antiallergic effect of the fructus of Evodia rutaecarpa and its constituents.
Journal: Biological & pharmaceutical bulletin 20070101
Title: Chemical and biological comparisons on Evodia with two related species of different locations and conditions.
Journal: Journal of ethnopharmacology 20061124
Title: Caspase-dependent and caspase-independent apoptosis induced by evodiamine in human leukemic U937 cells.
Journal: Molecular cancer therapeutics 20060901
Title: Determination of evodiamine and rutecarpine in human serum by liquid chromatography-tandem mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20060701
Title: Evodiamine inhibits in vitro angiogenesis: Implication for antitumorgenicity.
Journal: Life sciences 20060404
Title: Anti-inflammatory principles from the fruits of Evodia rutaecarpa and their cellular action mechanisms.
Journal: Archives of pharmacal research 20060401
Title: Development and validation of HPLC methods for the analysis of phenethylamine and indoloquinazoline alkaloids in Evodia species.
Journal: Journal of separation science 20060301
Title: [Effect of protein kinase C on human melanoma A375-S2 cell death induced by evodiamine].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20051101
Title: Evodiamine induced human melanoma A375-S2 cell death partially through interleukin 1 mediated pathway.
Journal: Biological & pharmaceutical bulletin 20050601
Title: Antitumor mechanism of evodiamine, a constituent from Chinese herb Evodiae fructus, in human multiple-drug resistant breast cancer NCI/ADR-RES cells in vitro and in vivo.
Journal: Carcinogenesis 20050501
Title: Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
Journal: The Journal of biological chemistry 20050429
Title: Roles of SIRT1 and phosphoinositide 3-OH kinase/protein kinase C pathways in evodiamine-induced human melanoma A375-S2 cell death.
Journal: Journal of pharmacological sciences 20050401
Title: Induction of mitotic arrest and apoptosis in human prostate cancer pc-3 cells by evodiamine.
Journal: The Journal of urology 20050101
Title: Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats.
Journal: Planta medica 20041201
Title: Evodiamine functions as an agonist for the vanilloid receptor TRPV1.
Journal: Organic & biomolecular chemistry 20040821
Title: [Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20040801
Title: Inhibitory effects of evodiamine on the growth of human prostate cancer cell line LNCaP.
Journal: International journal of cancer 20040710
Title: Induction of mitotic arrest and apoptosis by evodiamine in human leukemic T-lymphocytes.
Journal: Life sciences 20040521
Title: Inhibition by evodiamine of hepatocyte growth factor-induced invasion and migration of tumor cells.
Journal: Biological & pharmaceutical bulletin 20040401
Title: Atypical apoptosis in L929 cells induced by evodiamine isolated from Evodia rutaecarpa.
Journal: Journal of Asian natural products research 20040301
Title: Evodiamine induces tumor cell death through different pathways: apoptosis and necrosis.
Journal: Acta pharmacologica Sinica 20040101
Title: Intracellular regulation of evodiamine-induced A375-S2 cell death.
Journal: Biological & pharmaceutical bulletin 20031101
Title: [Evodiamine induces A375-S2 cell death through two different pathways].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20030901
Title: The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice.
Journal: Planta medica 20030501
Title: [Advances in pharmacological study of Evodia rutaecarpa and its effective constituents].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20030401
Title: Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030301
Title: Evodiamine, a constituent of Evodiae Fructus, induces anti-proliferating effects in tumor cells.
Journal: Cancer science 20030101
Title: Effects of evodiamine on gastrointestinal motility in male rats.
Journal: European journal of pharmacology 20021220
Title: Anti-invasive and metastatic activities of evodiamine.
Journal: Biological & pharmaceutical bulletin 20021101
Title: [Studies on evodiamine induced HeLa cell apoptosis].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20020901
Title: Modulation of drug-metabolizing enzymes by extracts of a herbal medicine Evodia rutaecarpa in C57BL/6J mice.
Journal: Life sciences 20020802
Title: Pharmacological profile of evodiamine in isolated rabbit corpus cavernosum.
Journal: European journal of pharmacology 20020620
Title: The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020301
Title: [Determination of evodiamine and rutaecarpine in Evodia rutaecarpa (Juss.) Benth after compatibility with Coptis chinensis Franch].
Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20011201
Title: Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist.
Journal: Planta medica 20011001
Title: Inhibitory effects of evodiamine on in vitro invasion and experimental lung metastasis of murine colon cancer cells.
Journal: Biological & pharmaceutical bulletin 20010801
Title: Inhibitory effect of evodiamine on aldosterone release by Zona glomerulosa cells in male rats.
Journal: The Chinese journal of physiology 20010630
Title: The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa, on the guinea-pig isolated right atria: possible involvement of vanilloid receptors.
Journal: Planta medica 20010401
Title: Wang S, et al. Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents. J Med Chem. 2015 Aug 27;58(16):6678-96.
Title: Li RF,et al. Effects of Evodiamine on the Pharmacokinetics of Dapoxetine and Its Metabolite Desmethyl Dapoxetine inRats. Pharmacology. 2016;97(1-2):43-7.
Title: Shi L, et al. Evodiamine exerts anti-tumor effects against hepatocellular carcinoma through inhibiting β-catenin-mediated angiogenesis. Tumour Biol. 2016 Sep;37(9):12791-12803.
