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52-76-6,MFCD00051135
Catalog No.:AA00I986

52-76-6 | 19-Norpregn-4-en-20-yn-17-ol, (17a)-

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25mg
98%(HPLC)
in stock  
$48.00   $34.00
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100mg
98%(HPLC)
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$97.00   $68.00
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1g
98%(HPLC)
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$243.00   $170.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I986
Chemical Name:
19-Norpregn-4-en-20-yn-17-ol, (17a)-
CAS Number:
52-76-6
Molecular Formula:
C20H28O
Molecular Weight:
284.4357
MDL Number:
MFCD00051135
SMILES:
C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2=CCCC[C@H]12
Properties
Computed Properties
 
Complexity:
523  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
4.5  

Literature

Title: Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish.

Journal: Toxicology and applied pharmacology 20160815

Title: Lipid peroxidation in judoists using oral contraceptives.

Journal: International journal of sports medicine 20121001

Title: Differences in prescription rates and odds ratios of antidepressant drugs in relation to individual hormonal contraceptives: a nationwide population-based study with age-specific analyses.

Journal: The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20120401

Title: [Endometrial cancer in a 25-year-old patient. Case study].

Journal: Ginekologia polska 20120301

Title: [Role of medical treatment for symptomatic leiomyoma management in premenopausal women].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20111201

Title: Comparison of the efficacy of three progestins in the treatment of simple endometrial hyperplasia without atypia.

Journal: Gynecologic and obstetric investigation 20110101

Title: Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

Journal: Molecular systems biology 20110101

Title: Deep vein thrombosis in a woman taking oral combined contraceptive pills.

Journal: Journal of pharmacology & pharmacotherapeutics 20110101

Title: Identification of novel functional inhibitors of acid sphingomyelinase.

Journal: PloS one 20110101

Title: Gene expression signatures of breast tissue before and after cross-sex hormone therapy in female-to-male transsexuals.

Journal: Fertility and sterility 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Oxidation of lynestrenol by the fungus Cunninghamella elegans.

Journal: Natural product research 20100101

Title: Protrhombotic effects of contraceptives.

Journal: Current pharmaceutical design 20100101

Title: The venous thrombotic risk of oral contraceptives, effects of oestrogen dose and progestogen type: results of the MEGA case-control study.

Journal: BMJ (Clinical research ed.) 20090101

Title: Safety, efficacy and patient satisfaction with continuous daily administration of levonorgestrel/ethinylestradiol oral contraceptives.

Journal: Patient preference and adherence 20090101

Title: Evaluation of extended and continuous use oral contraceptives.

Journal: Therapeutics and clinical risk management 20081001

Title: Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone.

Journal: The Journal of steroid biochemistry and molecular biology 20080501

Title: Laparoscopic hysterectomy of large uteri with uterine artery coagulation at its origin.

Journal: JSLS : Journal of the Society of Laparoendoscopic Surgeons 20080101

Title: Classification and pharmacology of progestins.

Journal: Maturitas 20080101

Title: [State of the hypothalamo-hypophyseal-ovarian system in young nullipara women with ectopia of the cervix of uterus during taking the hormonal contraceptives].

Journal: Georgian medical news 20071001

Title: Regressive liver adenomatosis following androgenic progestin therapy withdrawal: a case report with a 10-year follow-up and a molecular analysis.

Journal: European journal of endocrinology 20070601

Title: [Hormonal contraception and cervix of the uterus pathology].

Journal: Georgian medical news 20070401

Title: Oral progestagens before menopause and breast cancer risk.

Journal: British journal of cancer 20070312

Title: Benefits and risks of hormonal contraception for women.

Journal: GMS health technology assessment 20070101

Title: [Ectopia of cervix of the uterus and hormonal contraception].

Journal: Georgian medical news 20061201

Title: Birth control pills and nonprofessional voice: acoustic analyses.

Journal: Journal of speech, language, and hearing research : JSLHR 20061001

Title: Two routes of hormonal replacement therapy in symptomatic menopausal women after kidney transplantation.

Journal: Neuro endocrinology letters 20060601

Title: Effects of intranasal 17beta-estradiol administration on serum bioactive interleukin-6 and C-reactive protein levels in healthy postmenopausal women.

Journal: Menopause (New York, N.Y.) 20060101

Title: Breast cancer risk associated with different HRT formulations: a register-based case-control study.

Journal: BMC women's health 20060101

Title: In vivo induction of sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) by lynestrenol.

Journal: Indian journal of experimental biology 20050301

Title: Contraceptive vaginal rings releasing Nestorone and ethinylestradiol: a 1-year dose-finding trial.

Journal: Contraception 20050201

Title: Venous thromboembolism after high-dose chemotherapy in a patient with Hodgkin's lymphoma receiving the new oral contraceptive ethinylestradiol and drospirenone ('Yasmine').

Journal: Bone marrow transplantation 20050101

Title: [Multiple endometrial polyps in patient undergoing long-term gestagen therapy].

Journal: Srpski arhiv za celokupno lekarstvo 20050101

Title: A 3-year double-blind, randomized, controlled study on the influence of two oral contraceptives containing either 20 microg or 30 microg ethinylestradiol in combination with levonorgestrel on bone mineral density.

Journal: Contraception 20040301

Title: Classification and pharmacology of progestins.

Journal: Maturitas 20031210

Title: The effect of ethinyloestradiol and levonorgestrel on the CYP2C19-mediated metabolism of omeprazole in healthy female subjects.

Journal: British journal of clinical pharmacology 20030801

Title: Use of progestogen-only contraceptives/medications and lipid parameters in women age 40 to 42 years: results of a population-based cross-sectional Norwegian Survey.

Journal: Contraception 20020701

Title: FSH and ovarian response: spontaneous recovery of pituitary-ovarian activity during the pill-free period vs. exogenous recombinant FSH during high-dose combined oral contraceptives.

Journal: Clinical endocrinology 20020401

Title: Prospective randomized study comparing the GnRH-agonist leuprorelin acetate and the gestagen lynestrenol in the treatment of severe endometriosis.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20010601

Title: Leuprorelin and triptorelin: new indication. Preoperative treatment of uterine leiomyoma: no proven value.

Journal: Prescrire international 20010601

Title: [Endometriosis of the abdominal wall: diagnosis and treatment techniques].

Journal: Ginekologia polska 20010501

Title: Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.

Journal: The Cochrane database of systematic reviews 20010101

Title: Variegate porphyria with coexistent decrease in porphobilinogen deaminase activity.

Journal: Acta dermato-venereologica 20010101

Title: [Coronary disease and hormonal treatment during the perimenopausal period].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 19980101

Title: Camptocormia, a new side effect of sodium valproate.

Journal: Epilepsy research 19870701

Title: Oral contraceptive induced paraballism.

Journal: Clinical neurology and neurosurgery 19870101

Title: [Lipoprotein changes during hormonal treatment of endometriosis with lynestrenol and danazol].

Journal: Geburtshilfe und Frauenheilkunde 19840301

Title: [Occurrence and histological structure of adenocarcinoma of the endocervix after long-term use of oral contraceptives (author's transl)].

Journal: Geburtshilfe und Frauenheilkunde 19820401

Title: Oral contraceptives as a cause of erythema nodosum.

Journal: Archives of dermatology 19810801

Title: Erythema nodosum and oral contraceptives.

Journal: British medical journal 19771119

Title: [Adenoma of the liver and oral contraceptives].

Journal: Nederlands tijdschrift voor geneeskunde 19761211

Title: Steroid contraceptives: neuro-psychiatric & electroencephalographic complications.

Journal: The Journal of international medical research 19730101

Title: [Arterial hypertension during treatment with estro-progestative drugs].

Journal: Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise 19710101

Title: Pyridoxine and the pill.

Journal: Lancet (London, England) 19700418

Title: [Late cutaneous porphyria with sclerodermic syndrome revealed by taking estrogens, barbiturates and estro-progestational hormones].

Journal: Bulletin de la Societe francaise de dermatologie et de syphiligraphie 19690101

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Tags:52-76-6 Molecular Formula|52-76-6 MDL|52-76-6 SMILES|52-76-6 19-Norpregn-4-en-20-yn-17-ol, (17a)-