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522-48-5,MFCD00058029
Catalog No.:AA00I99C

522-48-5 | Tetrahydrozoline HCl

Pack Size
Purity
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Price(USD)
Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$16.00   $11.00
- +
5g
98%
in stock  
$24.00   $17.00
- +
25g
98%
in stock  
$97.00   $68.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I99C
Chemical Name:
Tetrahydrozoline HCl
CAS Number:
522-48-5
Molecular Formula:
C13H17ClN2
Molecular Weight:
236.7405
MDL Number:
MFCD00058029
SMILES:
C1CN=C(N1)C1CCCc2c1cccc2.Cl
NSC Number:
757339
Properties
Computed Properties
 
Complexity:
259  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  

Downstream Synthesis Route
Literature

Title: Use of tetrahydrozoline for chemical submission.

Journal: Forensic science international 20120910

Title: Development of prilocaine gels for enhanced local anesthetic action.

Journal: Archives of pharmacal research 20120701

Title: Drug-facilitated sexual assault using tetrahydrozoline.

Journal: Journal of forensic sciences 20120501

Title: Safety and efficacy of topical azithromycin ophthalmic solution 1.0% in the treatment of contact lens-related dry eye.

Journal: Eye & contact lens 20120301

Title: A randomized controlled trial of intralesional bevacizumab injection on primary pterygium: preliminary results.

Journal: Cornea 20111101

Title: Tetrahydrozoline (Visine®) concentrations in serum and urine during therapeutic ocular dosing: a necessary first step in determining an overdose.

Journal: Clinical toxicology (Philadelphia, Pa.) 20111101

Title: Serum concentrations in three children with unintentional tetrahydrozoline overdose.

Journal: Clinical toxicology (Philadelphia, Pa.) 20110601

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Naloxone use in a newborn with apnea due to tetrahydrozoline intoxication.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20100601

Title: A comparative kinetic and mechanistic study between tetrahydrozoline and naphazoline toward photogenerated reactive oxygen species.

Journal: Photochemistry and photobiology 20100101

Title: Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS).

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline.

Journal: Clinical toxicology (Philadelphia, Pa.) 20080201

Title: Patient use of Visine (tetrahydrozoline) masks Horner syndrome.

Journal: The British journal of ophthalmology 20080101

Title: Drug facilitated sexual assault using an over-the-counter ocular solution containing tetrahydrozoline (Visine).

Journal: Legal medicine (Tokyo, Japan) 20070701

Title: Comparative evaluation of antimicrobial efficacy of sodium hypochlorite, MTAD, and Tetraclean against Enterococcus faecalis biofilm.

Journal: Journal of endodontics 20070701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: [Drug administration in newborns. Is clinical experience enough?].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20060401

Title: Ophthalmic delivery systems based on drug-polymer-polymer ionic ternary interaction: in vitro and in vivo characterization.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060101

Title: [Systemic involvement in premature infants after intranasal administration of tetryzoline drops].

Journal: Anales de pediatria (Barcelona, Spain : 2003) 20051001

Title: Effects of two eye drop products on computer users with subjective ocular discomfort.

Journal: Optometry (St. Louis, Mo.) 20050101

Title: Simple HPLC determination of benzalkonium chloride in ophthalmic formulations containing antazoline and tetrahydrozoline.

Journal: PDA journal of pharmaceutical science and technology 20050101

Title: Sinoatrial node arrest following tetrahydrozoline ingestion.

Journal: The Journal of emergency medicine 20041001

Title: [The tolerability of nasal drugs with special regard to preservatives and physico-chemical parameters].

Journal: Laryngo- rhino- otologie 20031101

Title: Pediatric Visine (tetrahydrozoline) ingestion: case report and review of imidazoline toxicity.

Journal: Veterinary and human toxicology 20030801

Title: Simultaneous determination of ofloxacin, tetrahydrozoline hydrochloride, and prednisolone acetate by high-performance liquid chromatography.

Journal: Journal of chromatographic science 20020901

Title: Electron microscopic analysis of the effects of chemical retraction agents on cultured rat keratinocytes.

Journal: The Journal of prosthetic dentistry 20020101

Title: Viability of fibroblasts in cell culture after treatment with different chemical retraction agents.

Journal: Journal of oral rehabilitation 20020101

Title: Gingival inflammatory response induced by chemical retraction agents in beagle dogs.

Journal: The International journal of prosthodontics 20020101

Title: Gingival tissue inflammatory response following treatment with chemical retraction agents in Beagle dogs.

Journal: Pflugers Archiv : European journal of physiology 20010101

Title: E Kisilevsky, et al. Anterior and posterior segment vasculopathy associated with long-term use of tetrahydrozoline. CMAJ. 2018 Oct 9;190(40):E1208.

Title: Judy Peat, et al.Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS). Methods Mol Biol. 2010;603:501-8.

Title: Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19(3): 2037-2044.

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