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553-12-8,MFCD00151109
Catalog No.:AA00I9SD

553-12-8 | 21H,23H-Porphine-2,18-dipropanoic acid,7,12-diethenyl-3,8,13,17-tetramethyl-

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250mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I9SD
Chemical Name:
21H,23H-Porphine-2,18-dipropanoic acid,7,12-diethenyl-3,8,13,17-tetramethyl-
CAS Number:
553-12-8
Molecular Formula:
C34H34N4O4
Molecular Weight:
562.6582
MDL Number:
MFCD00151109
SMILES:
C=CC1=C(C)C2=N/C/1=C\c1[nH]c(c(c1C)C=C)/C=C/1\N=C(/C=c/3\[nH]/c(=C\2)/c(C)c3CCC(=O)O)C(=C1C)CCC(=O)O
Properties
Computed Properties
 
Complexity:
1010  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
8  
XLogP3:
4.6  

Literature

Title: Chronic Treatment with Isoniazid Causes Protoporphyrin IX Accumulation in Mouse Liver.

Journal: Chemical research in toxicology 20160815

Title: Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20160601

Title: Constitutive active/androstane receptor, peroxisome proliferator-activated receptor α, and cytotoxicity are involved in oxadiazon-induced liver tumor development in mice.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20160201

Title: Structural requirements within protoporphyrin IX in the inhibition of heat shock protein 90.

Journal: Chemico-biological interactions 20130625

Title: Reciprocal regulation of cyclooxygenase 2 and heme oxygenase 1 upon arsenic trioxide exposure in normal human lung fibroblast.

Journal: Journal of biochemical and molecular toxicology 20130601

Title: Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 2: theoretical, biochemical and practical aspects.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20121201

Title: Interaction between holo transferrin and HSA-PPIX complex in the presence of lomefloxacin: an evaluation of PPIX aggregation in protein-protein interactions.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121101

Title: Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 1: Clinical, radiological and pathological studies.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20121101

Title: Soluble diamagnetic model for malaria pigment: coordination chemistry of gallium(III)protoporphyrin-IX.

Journal: Inorganic chemistry 20121015

Title: On the autofluorescence of fingermarks.

Journal: Forensic science international 20121010

Title: Sodium butyrate increases the effect of the photodynamic therapy: a mechanism that involves modulation of gene expression and differentiation in astrocytoma cells.

Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20121001

Title: Comparison of the uptake of 5-aminolevulinic acid and its methyl ester in keratinocytes and skin.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20121001

Title: Protoporphyrin IX formation and photobleaching in different layers of normal human skin: methyl- and hexylaminolevulinate and different light sources.

Journal: Experimental dermatology 20121001

Title: Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR).

Journal: The Journal of biological chemistry 20120914

Title: Differential cytotoxic response in keloid fibroblasts exposed to photodynamic therapy is dependent on photosensitiser precursor, fluence and location of fibroblasts within the lesion.

Journal: Archives of dermatological research 20120901

Title: Gadolinium- and 5-aminolevulinic acid-induced protoporphyrin IX levels in human gliomas: an ex vivo quantitative study to correlate protoporphyrin IX levels and blood-brain barrier breakdown.

Journal: Journal of neuropathology and experimental neurology 20120901

Title: [Fluorescence diagnosis of non-melanoma skin cancer].

Journal: Orvosi hetilap 20120826

Title: Conserved chloroplast open-reading frame ycf54 is required for activity of the magnesium protoporphyrin monomethylester oxidative cyclase in Synechocystis PCC 6803.

Journal: The Journal of biological chemistry 20120810

Title: Effect of low temperature on chlorophyll biosynthesis in albinism line of wheat (Triticum aestivum) FA85.

Journal: Physiologia plantarum 20120701

Title: Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells.

Journal: Journal of neuro-oncology 20120701

Title: Stem cell-based photodynamic therapy.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120701

Title: Validation of the protoporphyrin IX-triplet state lifetime technique for mitochondrial oxygen measurements in the skin.

Journal: Optics letters 20120701

Title: In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope.

Journal: Journal of biomedical optics 20120701

Title: Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways.

Journal: Investigational new drugs 20120601

Title: Radiosensitizing effect of 5-aminolevulinic acid-induced protoporphyrin IX in glioma cells in vitro.

Journal: Oncology reports 20120601

Title: 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.

Journal: European journal of medicinal chemistry 20120601

Title: The 18 kDa mitochondrial translocator protein (TSPO) prevents accumulation of protoporphyrin IX. Involvement of reactive oxygen species (ROS).

Journal: Current molecular medicine 20120501

Title: Pharmacological induction of heme oxygenase-1 by a triterpenoid protects neurons against ischemic injury.

Journal: Stroke 20120501

Title: Heme oxygenase-1 promotes the persistence of Leishmania chagasi infection.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20120501

Title: Iron(III) protoporphyrin IX complexes of the antimalarial Cinchona alkaloids quinine and quinidine.

Journal: ACS chemical biology 20120420

Title: ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

Journal: The Journal of biological chemistry 20120413

Title: Apoptosis induced by sonodynamic treatment by protoporphyrin IX on MDA-MB-231 cells.

Journal: Ultrasonics 20120401

Title: PpIX fluorescence combined with auto-fluorescence is more accurate than PpIX fluorescence alone in fluorescence detection of non-melanoma skin cancer: an intra-patient direct comparison study.

Journal: Lasers in surgery and medicine 20120401

Title: 5-Aminolevulinic acid-induced protoporphyrin IX fluorescence as immediate intraoperative indicator to improve the safety of malignant or high-grade brain tumor diagnosis in frameless stereotactic biopsies.

Journal: Acta neurochirurgica 20120401

Title: Porphyrin biodistribution in UV-exposed murine skin after methyl- and hexyl-aminolevulinate incubation.

Journal: Experimental dermatology 20120401

Title: ¹¹C-methionine uptake and intraoperative 5-aminolevulinic acid-induced fluorescence as separate index markers of cell density in glioma: a stereotactic image-histological analysis.

Journal: Cancer 20120315

Title: Cobinamides are novel coactivators of nitric oxide receptor that target soluble guanylyl cyclase catalytic domain.

Journal: The Journal of pharmacology and experimental therapeutics 20120301

Title: Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative.

Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20120301

Title: Protoporphyrin IX-dependent photodynamic production of endogenous ROS stimulates cell proliferation.

Journal: European journal of cell biology 20120301

Title: Comparison of noninvasive photodynamic therapy dosimetry methods using a dynamic model of ALA-PDT of human skin.

Journal: Physics in medicine and biology 20120207

Title: C-terminal residues of oryza sativa GUN4 are required for the activation of the ChlH subunit of magnesium chelatase in chlorophyll synthesis.

Journal: FEBS letters 20120203

Title: Effect of surfactant on 5-aminolevulinic acid uptake and PpIX generation in human cholangiocarcinoma cell.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120201

Title: Protective effects of β-carotene and melanin against protoporphyrine IX-induced phototoxicity in the photo hen's egg test.

Journal: Photodermatology, photoimmunology & photomedicine 20120201

Title: [The role of tetrapyrrol photosensitizers in photoinduced variation of free radical characteristics of rat blood in endotoxic shock].

Journal: Biofizika 20120101

Title: 5-aminolevulinic acid-incorporated poly(vinyl alcohol) nanofiber-coated metal stent for application in photodynamic therapy.

Journal: International journal of nanomedicine 20120101

Title: [Soluble guanylate cyclase in the molecular mechanism underlying the therapeutic action of drugs].

Journal: Biomeditsinskaia khimiia 20120101

Title: Poly(L-histidine)-tagged 5-aminolevulinic acid prodrugs: new photosensitizing precursors of protoporphyrin IX for photodynamic colon cancer therapy.

Journal: International journal of nanomedicine 20120101

Title: Low-intensity ultrasound combined with 5-aminolevulinic acid administration in the treatment of human tongue squamous carcinoma.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

Title: Serum-dependent export of protoporphyrin IX by ATP-binding cassette transporter G2 in T24 cells.

Journal: Molecular and cellular biochemistry 20111201

Title: δ-Aminolevulinic acid and its methyl ester induce the formation of Protoporphyrin IX in cultured sensory neurones.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20111201

Title: Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy.

Journal: Journal of dermatological science 20111201

Title: Modulating ALA-PDT efficacy of mutlidrug resistant MCF-7 breast cancer cells using ALA prodrug.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111201

Title: Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain.

Journal: Journal of biomedical optics 20111201

Title: Photosensitizer-loaded dendrimer-modified multi-walled carbon nanotubes for photodynamic therapy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20111130

Title: Aloe-emodin as antiproliferative and differentiating agent on human U937 monoblastic leukemia cells.

Journal: Life sciences 20111121

Title: Simultaneously targeting mitochondria and endoplasmic reticulum by photodynamic therapy induces apoptosis in human lymphoma cells.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111101

Title: Combined fluorescence and reflectance spectroscopy for in vivo quantification of cancer biomarkers in low- and high-grade glioma surgery.

Journal: Journal of biomedical optics 20111101

Title: Iron-coordinating tyrosine is a key determinant of NEAT domain heme transfer.

Journal: Journal of molecular biology 20111028

Title: 5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor.

Journal: Lung cancer (Amsterdam, Netherlands) 20111001

Title: Protoporphyrin retention in hepatocytes and Kupffer cells prevents sclerosing cholangitis in erythropoietic protoporphyria mouse model.

Journal: Gastroenterology 20111001

Title: Oxygen-dependent delayed fluorescence measured in skin after topical application of 5-aminolevulinic acid.

Journal: Journal of biophotonics 20111001

Title: Carbon dots as antioxidants and prooxidants.

Journal: Journal of biomedical nanotechnology 20111001

Title: Retained topical delivery of 5-aminolevulinic acid using cationic ultradeformable liposomes for photodynamic therapy.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110918

Title: Isolation and characterization of squamous carcinoma cells resistant to photodynamic therapy.

Journal: Journal of cellular biochemistry 20110901

Title: Myrrh mediates haem oxygenase-1 expression to suppress the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages.

Journal: The Journal of pharmacy and pharmacology 20110901

Title: Photodynamic therapy (PDT) - Initiation of apoptosis via activation of stress-activated p38 MAPK and JNK signal pathway in H460 cell lines.

Journal: Photodiagnosis and photodynamic therapy 20110901

Title: Photobleaching-based method to individualize irradiation time during interstitial 5-aminolevulinic acid photodynamic therapy.

Journal: Photodiagnosis and photodynamic therapy 20110901

Title: Protoporphyrin IX fluorescence contrast in invasive glioblastomas is linearly correlated with Gd enhanced magnetic resonance image contrast but has higher diagnostic accuracy.

Journal: Journal of biomedical optics 20110901

Title: Fluorescence detection and depletion of T47D breast cancer cells from human mononuclear cell-enriched blood preparations by photodynamic treatment: Basic in vitro experiments towards the removal of circulating tumor cells.

Journal: Lasers in surgery and medicine 20110901

Title: Intracutaneous ALA photodynamic therapy: dose-dependent targeting of skin structures.

Journal: Lasers in surgery and medicine 20110901

Title: Hexaminolevulinate-mediated photodynamic purging of marrow grafts with murine breast carcinoma.

Journal: Bone marrow transplantation 20110801

Title: The centrality of PBGD expression levels on ALA-PDT efficacy.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110801

Title: A protective protein matrix improves the discrimination of nitroxyl from nitric oxide by MnIII protoporphyrinate IX in aerobic media.

Journal: Journal of inorganic biochemistry 20110801

Title: Fluorescence illuminates the way ..

Journal: Neuro-oncology 20110801

Title: δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy.

Journal: Neuro-oncology 20110801

Title: Photomicronucleus assay of phototoxic and pseudophotoclastogenic chemicals in human keratinocyte NCTC2544 cells.

Journal: Mutation research 20110714

Title: Neonatal bone marrow transplantation prevents liver disease in a murine model of erythropoietic protoporphyria.

Journal: Journal of hepatology 20110701

Title: Sonodynamically induced anti-tumor effect with protoporphyrin IX on hepatoma-22 solid tumor.

Journal: Ultrasonics 20110701

Title: Analysis of liquid crystalline nanoparticles by small angle X-ray diffraction: evaluation of drug and pharmaceutical additives influence on the internal structure.

Journal: Journal of pharmaceutical sciences 20110701

Title: Comparative study of the bactericidal effects of 5-aminolevulinic acid with blue and red light on Propionibacterium acnes.

Journal: The Journal of dermatology 20110701

Title: Measuring versus seeing.

Journal: Journal of neurosurgery 20110701

Title: Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker.

Journal: Journal of neurosurgery 20110701

Title: Targeting of sebaceous glands by δ-aminolevulinic acid-based photodynamic therapy: An in vivo study.

Journal: Lasers in surgery and medicine 20110701

Title: Comparative study of protoporphyrin IX fluorescence image enhancement methods to improve an optical imaging system for oral cancer detection.

Journal: Journal of biomedical optics 20110701

Title: Proton-coupled electron transfer reactions at a heme-propionate in an iron-protoporphyrin-IX model compound.

Journal: Journal of the American Chemical Society 20110608

Title: Simulation of fractionated and continuous irradiation in photodynamic therapy: study the differences between photobleaching and singlet oxygen dose deposition.

Journal: Australasian physical & engineering sciences in medicine 20110601

Title: An investigation of the fluorescence induced by topical application of 5-aminolaevulinic acid and methyl aminolaevulinate at different body sites on normal human skin.

Journal: Photodiagnosis and photodynamic therapy 20110601

Title: Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites.

Journal: The British journal of dermatology 20110601

Title: Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.

Journal: Blood 20110519

Title: Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay.

Journal: Free radical biology & medicine 20110501

Title: Linear free energy relationships predict coordination and π-stacking interactions of small molecules with ferriprotoporphyrin IX.

Journal: Journal of inorganic biochemistry 20110501

Title: Drug delivery technologies and immunological aspects of photodynamic therapy.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110501

Title: Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas.

Journal: Neurosurgical focus 20110501

Title: The effect of air cooling pain relief on protoporphyrin IX photobleaching and clinical efficacy during dermatological photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20110404

Title: Biodistribution of PVP-hypericin and hexaminolevulinate-induced PpIX in normal and orthotopic tumor-bearing rat urinary bladder.

Journal: Cancer chemotherapy and pharmacology 20110401

Title: A novel proteomic approach reveals a role for Mg-protoporphyrin IX in response to oxidative stress.

Journal: Physiologia plantarum 20110401

Title: Monitoring of native fluorescence induced by a glucose diet in Wistar rats.

Journal: Photomedicine and laser surgery 20110401

Title: Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial basal cell carcinomas.

Journal: Journal of biomedical optics 20110401

Title: Coregistered fluorescence-enhanced tumor resection of malignant glioma: relationships between δ-aminolevulinic acid-induced protoporphyrin IX fluorescence, magnetic resonance imaging enhancement, and neuropathological parameters. Clinical article.

Journal: Journal of neurosurgery 20110301

Title: Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy.

Journal: British journal of cancer 20110301

Title: Enhancement of blood porphyrin emission intensity with aminolevulinic acid administration: a new concept for photodynamic diagnosis of early prostate cancer.

Journal: Photodiagnosis and photodynamic therapy 20110301

Title: Monitoring the accumulation and dissipation of the photosensitizer protoporphyrin IX during standard dermatological methyl-aminolevulinate photodynamic therapy utilizing non-invasive fluorescence imaging and quantification.

Journal: Photodiagnosis and photodynamic therapy 20110301

Title: [Nitric oxide donors activated by two-photon excitation].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110301

Title: Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity.

Journal: Journal of the American Chemical Society 20110202

Title: Quinolone compounds enhance delta-aminolevulinic acid-induced accumulation of protoporphyrin IX and photosensitivity of tumour cells.

Journal: Journal of biochemistry 20110201

Title: Hemin and magnesium-protoporphyrin IX induce global changes in gene expression in Chlamydomonas reinhardtii.

Journal: Plant physiology 20110201

Title: Epithelioid glioblastoma changed to typical glioblastoma: the methylation status of MGMT promoter and 5-ALA fluorescence.

Journal: Brain tumor pathology 20110201

Title: Precise comparison of protoporphyrin IX fluorescence spectra with pathological results for brain tumor tissue identification.

Journal: Brain tumor pathology 20110201

Title: Intense pulse light and 5-ALA PDT: phototoxic effects in vitro depend on the spectral overlap with protoporphyrine IX but do not match cut-off filter notations.

Journal: Lasers in surgery and medicine 20110201

Title: Detection and photodynamic therapy of inflamed atherosclerotic plaques in the carotid artery of rabbits.

Journal: Journal of photochemistry and photobiology. B, Biology 20110110

Title: Evaluation of photodynamic therapy (PDT) procedures using microfluidic system.

Journal: Analytica chimica acta 20110110

Title: Targeting of p53 and its homolog p73 by protoporphyrin IX.

Journal: FEBS letters 20110103

Title: Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer.

Journal: Lasers in medical science 20110101

Title: Symbiotic association between soybean plants and Bradyrhizobium japonicum develops oxidative stress and heme oxygenase-1 induction at early stages.

Journal: Redox report : communications in free radical research 20110101

Title: Effect of 5-aminolevulinic acid-based photodynamic therapy via reactive oxygen species in human cholangiocarcinoma cells.

Journal: International journal of nanomedicine 20110101

Title: An in vitro comparison of the effects of the iron-chelating agents, CP94 and dexrazoxane, on protoporphyrin IX accumulation for photodynamic therapy and/or fluorescence guided resection.

Journal: Photochemistry and photobiology 20110101

Title: Utility of intraoperative fluorescent diagnosis of residual hemangioblastoma using 5-aminolevulinic acid.

Journal: Neurology India 20110101

Title: Fluorescence photobleaching of ALA and ALA-heptyl ester induced protoporphyrin IX during photodynamic therapy of normal hairless mouse skin: a comparison of two light sources and different illumination schemes.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20110101

Title: Identification and characterization of an inhibitory metal ion-binding site in ferrochelatase.

Journal: The Journal of biological chemistry 20101231

Title: The role of nitric oxide in the treatment of tumours with aminolaevulinic acid-induced photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20101202

Title: Identification of specific inhibitors for a trypanosomatid RNA editing reaction.

Journal: RNA (New York, N.Y.) 20101201

Title: Two-photon irradiation of an intracellular singlet oxygen photosensitizer: achieving localized sub-cellular excitation in spatially-resolved experiments.

Journal: Free radical research 20101201

Title: Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy.

Journal: Photodiagnosis and photodynamic therapy 20101201

Title: Determination of time-dependent protoporphyrin IX concentration for photodynamic therapy dosimetry in a mice colon tumor model using fluorescence spectroscopy.

Journal: Applied spectroscopy 20101201

Title: Intrinsic fluorescence of protoporphyrin IX from blood samples can yield information on the growth of prostate tumours.

Journal: Journal of fluorescence 20101101

Title: Tetrapyrrole binding affinity of the murine and human p22HBP heme-binding proteins.

Journal: Journal of molecular graphics & modelling 20101101

Title: The efficacy of photodynamic diagnosis in defining the lateral border between a tumor and a tumor-free area during Mohs micrographic surgery.

Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: BchJ and BchM interact in a 1 : 1 ratio with the magnesium chelatase BchH subunit of Rhodobacter capsulatus.

Journal: The FEBS journal 20101101

Title: ABCG2 transports and transfers heme to albumin through its large extracellular loop.

Journal: The Journal of biological chemistry 20101022

Title: Hexaminolevulinate-mediated photodynamic purging of leukemia cells from BM.

Journal: Bone marrow transplantation 20101001

Title: Microneedle pre-treatment of human skin improves 5-aminolevulininc acid (ALA)- and 5-aminolevulinic acid methyl ester (MAL)-induced PpIX production for topical photodynamic therapy without increase in pain or erythema.

Journal: Pharmaceutical research 20101001

Title: Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin.

Journal: The Journal of biological chemistry 20100910

Title: Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma.

Journal: Head & neck 20100901

Title: Penetration enhancement of two topical 5-aminolaevulinic acid formulations for photodynamic therapy by erbium:YAG laser ablation of the stratum corneum: continuous versus fractional ablation.

Journal: Experimental dermatology 20100901

Title: Reduction of cutaneous photosensitivity by application of ointment containing ferrous or cobaltous ions concomitant with the use of topical protoporphyrin IX precursors.

Journal: Photodiagnosis and photodynamic therapy 20100901

Title: In vivo temporal evolution of ALA-induced normalized fluorescence at different anatomical locations of oral cavity: application to improve cancer diagnostic contrast and potential.

Journal: Photodiagnosis and photodynamic therapy 20100901

Title: Antitumor properties of aloe-emodin and induction of transglutaminase 2 activity in B16-F10 melanoma cells.

Journal: Life sciences 20100828

Title: Fluorescence induction of protoporphyrin IX by a new 5-aminolevulinic acid nanoemulsion used for photodynamic therapy in a full-thickness ex vivo skin model.

Journal: Experimental dermatology 20100801

Title: In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography.

Journal: Synapse (New York, N.Y.) 20100801

Title: Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.

Journal: International journal of oral and maxillofacial surgery 20100801

Title: Factors influencing pain intensity during topical photodynamic therapy of complete cosmetic units for actinic keratoses.

Journal: Journal of the American Academy of Dermatology 20100801

Title: Comparison of pharmacokinetics, intracellular localizations and sonodynamic efficacy of endogenous and exogenous protoporphyrin IX in sarcoma 180 cells.

Journal: Ultrasonics 20100801

Title: Improving intraoperative visualization of anaplastic foci within gliomas.

Journal: Neurosurgery 20100801

Title: Fractional laser as a tool to enhance the skin permeation of 5-aminolevulinic acid with minimal skin disruption: a comparison with conventional erbium:YAG laser.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20100714

Title: The effects of keratolytic pretreatment prior to fluorescence diagnosis and photodynamic therapy with aminolevulinic acid-induced porphyrins in psoriasis.

Journal: The Journal of dermatological treatment 20100701

Title: Photodynamic therapy with intradermal administration of 5-aminolevulinic acid for port-wine stains.

Journal: The Journal of dermatological treatment 20100701

Title: Nitric oxide blocks cellular heme insertion into a broad range of heme proteins.

Journal: Free radical biology & medicine 20100601

Title: Validation of a non-invasive fluorescence imaging system to monitor dermatological PDT.

Journal: Photodiagnosis and photodynamic therapy 20100601

Title: Demonstration of protoporphyrin IX (PpIX) localized to areas of palmar skin injected with 5-aminolevulinic acid (ALA) and pre-treated with a fractionated CO2 laser prior to topically applied ALA.

Journal: Photodiagnosis and photodynamic therapy 20100601

Title: Reduction of arsenic-induced cytotoxicity through Nrf2/HO-1 signaling in HepG2 cells.

Journal: The Journal of toxicological sciences 20100601

Title: In vivo production of catalase containing haem analogues.

Journal: The FEBS journal 20100601

Title: A case of Bowen's disease successfully treated by photodynamic therapy.

Journal: Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20100601

Title: Study of blood porphyrin spectral profile for diagnosis of chronic renal failure.

Journal: Journal of fluorescence 20100501

Title: Folic acid-conjugated chitosan nanoparticles enhanced protoporphyrin IX accumulation in colorectal cancer cells.

Journal: Bioconjugate chemistry 20100421

Title: Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress.

Journal: Gastroenterology 20100401

Title: Sonodynamically induced apoptosis by protoporphyrin IX on hepatoma-22 cells in vitro.

Journal: Ultrasound in medicine & biology 20100401

Title: The influence of temperature on 5-aminolevulinic acid-based photodynamic reaction in keratinocytes in vitro.

Journal: Photodermatology, photoimmunology & photomedicine 20100401

Title: Two coregulated efflux transporters modulate intracellular heme and protoporphyrin IX availability in Streptococcus agalactiae.

Journal: PLoS pathogens 20100401

Title: Desferrioxamine shows different potentials for enhancing 5-aminolaevulinic acid-based photodynamic therapy in several cutaneous cell lines.

Journal: Lasers in medical science 20100301

Title: Photodynamic antimicrobial activity of avian eggshell pigments.

Journal: FEBS letters 20100219

Title: Boron-containing protoporphyrin IX derivatives and their modification for boron neutron capture therapy: synthesis, characterization, and comparative in vitro toxicity evaluation.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100201

Title: Nitric oxide sensitive guanylyl cyclase activity decreases during cerebral postnatal development because of a reduction in heterodimerization.

Journal: Journal of neurochemistry 20100101

Title: Intralesional photodynamic therapy: a comment on 'Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy' by Gerritsen et al.

Journal: Dermatology (Basel, Switzerland) 20100101

Title: Deferoxamine iron chelation increases delta-aminolevulinic acid induced protoporphyrin IX in xenograft glioma model.

Journal: Photochemistry and photobiology 20100101

Title: Preferential accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in breast cancer: a comprehensive study on six breast cell lines with varying phenotypes.

Journal: Journal of biomedical optics 20100101

Title: Apoptosis-accommodating effect of nitric oxide in photodynamically stressed tumor cells.

Journal: Photochemistry and photobiology 20100101

Title: Metronomic PDT and cell death pathways.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Application of 5-aminolevulinic acid and its derivatives for photodynamic therapy in vitro and in vivo.

Journal: Methods in molecular biology (Clifton, N.J.) 20100101

Title: Fractionated illumination at low fluence rate photodynamic therapy in mice.

Journal: Photochemistry and photobiology 20100101

Title: The hydroxypyridinone iron chelator CP94 can enhance PpIX-induced PDT of cultured human glioma cells.

Journal: Photochemistry and photobiology 20100101

Title: 5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors.

Journal: Photochemistry and photobiology 20100101

Title: Noninvasive fluorescence monitoring of protoporphyrin IX production and clinical outcomes in actinic keratoses following short-contact application of 5-aminolevulinate.

Journal: Journal of biomedical optics 20100101

Title: 5-ALA derivative-mediated photoinactivation of Propionibacterium acnes.

Journal: Journal of dermatological science 20091201

Title: Enlightened protein: Fhit tumor suppressor protein structure and function and its role in the toxicity of protoporphyrin IX-mediated photodynamic reaction.

Journal: Toxicology and applied pharmacology 20091201

Title: Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937.

Journal: Cell biochemistry and function 20091201

Title: Heating increases protoporphyrin IX production in normal skin after delivery of 5-aminolevulinic acid by iontophoresis.

Journal: Photodermatology, photoimmunology & photomedicine 20091201

Title: A comparative study on the enhancement efficacy of specific and non-specific iron chelators for protoporphyrin IX production and photosensitization in HaCat cells.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20091201

Title: Precise detection of lymph node metastases in mouse rectal cancer by using 5-aminolevulinic acid.

Journal: International journal of cancer 20091115

Title: An enzyme-coupled continuous spectrophotometric assay for magnesium protoporphyrin IX methyltransferases.

Journal: Analytical biochemistry 20091115

Title: Treatment of perianal Paget's disease using photodynamic therapy with assistance of fluorescence examination: case report.

Journal: Lasers in medical science 20091101

Title: A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin.

Journal: Experimental dermatology 20091101

Title: Topical delivery of 5-aminolevulinic acid-encapsulated ethosomes in a hyperproliferative skin animal model using the CLSM technique to evaluate the penetration behavior.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091101

Title: Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema.

Journal: The British journal of dermatology 20091101

Title: Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT.

Journal: Lasers in surgery and medicine 20091101

Title: Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.

Journal: International journal of cancer 20091001

Title: Photochemically induced increase in endothelial permeability regulated by RhoA activation.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001

Title: Silencing of ALA dehydratase affects ALA-photodynamic therapy efficacy in K562 erythroleukemic cells.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001

Title: Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia.

Journal: Photomedicine and laser surgery 20091001

Title: Signaling events in apoptotic photokilling of 5-aminolevulinic acid-treated tumor cells: inhibitory effects of nitric oxide.

Journal: Free radical biology & medicine 20090915

Title: Porphyrins promote the association of GENOMES UNCOUPLED 4 and a Mg-chelatase subunit with chloroplast membranes.

Journal: The Journal of biological chemistry 20090911

Title: New aspects in photodynamic therapy of actinic keratoses.

Journal: Journal of photochemistry and photobiology. B, Biology 20090904

Title: Porphyrin synthesis from aminolevulinic acid esters in endothelial cells and its role in photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20090904

Title: Site-directed mutagenesis and computational study of the Y366 active site in Bacillus subtilis protoporphyrinogen oxidase.

Journal: Amino acids 20090901

Title: The interplay between iron and zinc metabolism in Aspergillus fumigatus.

Journal: Fungal genetics and biology : FG & B 20090901

Title: Parallel pigment and transcriptomic analysis of four barley albina and xantha mutants reveals the complex network of the chloroplast-dependent metabolism.

Journal: Plant molecular biology 20090901

Title: Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells.

Journal: The British journal of dermatology 20090801

Title: A time course investigation of the fluorescence induced by topical application of 5-aminolevulinic acid and methyl aminolevulinate on normal human skin.

Journal: Photodermatology, photoimmunology & photomedicine 20090801

Title: Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit.

Journal: Cancer letters 20090718

Title: Improved peptide prodrugs of 5-ALA for PDT: rationalization of cellular accumulation and protoporphyrin IX production by direct determination of cellular prodrug uptake and prodrug metabolization.

Journal: Journal of medicinal chemistry 20090709

Title: Analysis of chlorophylls and their derivatives by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.

Journal: Analytical biochemistry 20090701

Title: [Intraoperative photo-dynamic diagnosis of brain tumors].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20090701

Title: Ros production by endogenously generated Protoporphyrin IX in murine leukemia cells.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20090701

Title: Surgical outcomes of fluorescence-guided laparoscopic partial nephrectomy using 5-aminolevulinic acid-induced protoporphyrin IX.

Journal: The Journal of surgical research 20090615

Title: Mitochondrial oxygen tension within the heart.

Journal: Journal of molecular and cellular cardiology 20090601

Title: Sulfasalazine induces haem oxygenase-1 via ROS-dependent Nrf2 signalling, leading to control of neointimal hyperplasia.

Journal: Cardiovascular research 20090601

Title: Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090515

Title: Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20090417

Title: Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy.

Journal: Clinical and experimental dermatology 20090401

Title: Induction of protoporphyrin IX by aminolaevulinic acid in actinic keratosis, psoriasis and normal skin: preferential porphyrin enrichment in differentiated cells.

Journal: The British journal of dermatology 20090401

Title: Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism.

Journal: British journal of cancer 20090310

Title: Influence of formulation factors on PpIX production and photodynamic action of novel ALA-loaded microparticles.

Journal: Biopharmaceutics & drug disposition 20090301

Title: Hypericin and 5-aminolevulinic acid-induced protoporphyrin IX induce enhanced phototoxicity in human endometrial cancer cells with non-coherent white light.

Journal: Photodiagnosis and photodynamic therapy 20090301

Title: Interactions of protoporphyrin IX and its derivatives with benzodiazepine receptor.

Journal: Photodiagnosis and photodynamic therapy 20090301

Title: Interactions of peripheral-type benzodiazepine receptor with diamino acid derivatives of protoporphyrin IX.

Journal: Journal of photochemistry and photobiology. B, Biology 20090209

Title: Influence of protoporphyrin IX amino acid substituents on affinity to human breast adenocarcinoma MCF-7 cells.

Journal: Biotechnic & histochemistry : official publication of the Biological Stain Commission 20090201

Title: Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: role for heme oxygenase-1 down-modulation.

Journal: Chemico-biological interactions 20090115

Title: Damage effects of protoporphyrin IX - sonodynamic therapy on the cytoskeletal F-actin of Ehrlich ascites carcinoma cells.

Journal: Ultrasonics sonochemistry 20090101

Title: Heme oxygenase is necessary for the excitatory response of cultured neonatal rat rostral ventrolateral medulla neurons to hypoxia.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090101

Title: Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy.

Journal: Dermatology (Basel, Switzerland) 20090101

Title: Skin and mucosal fluorescence diagnosis with different light sources.

Journal: European journal of dermatology : EJD 20090101

Title: Depth profile of protoporphyrin IX fluorescence in an amelanotic mouse melanoma model.

Journal: Photochemistry and photobiology 20090101

Title: Noninvasive measurement of aminolevulinic acid-induced protoporphyrin IX fluorescence allowing detection of murine glioma in vivo.

Journal: Journal of biomedical optics 20090101

Title: Imaging of glioma tumor with endogenous fluorescence tomography.

Journal: Journal of biomedical optics 20090101

Title: Improved diagnosis of oral premalignant lesions in submucous fibrosis patients with 5-aminolevulinic acid induced PpIX fluorescence.

Journal: Journal of biomedical optics 20090101

Title: Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target.

Journal: PloS one 20090101

Title: Regulation of heme synthesis and proteasomal activity by copper: possible implications for Wilson's disease.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20090101

Title: A preliminary study of protoporphyrin-IX as a potential candidate for identification of lung cancer cells using fluorescence microscopy.

Journal: Photodiagnosis and photodynamic therapy 20090101

Title: Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas.

Journal: Pathobiology : journal of immunopathology, molecular and cellular biology 20090101

Title: [Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].

Journal: Medicina (Kaunas, Lithuania) 20090101

Title: Ligand binding to the Fe(III)-protoporphyrin IX complex of phosphodiesterase from Escherichia coli (Ec DOS) markedly enhances catalysis of cyclic di-GMP: roles of Met95, Arg97, and Phe113 of the putative heme distal side in catalytic regulation and ligand binding.

Journal: Biochemistry 20081216

Title: Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma.

Journal: Journal of photochemistry and photobiology. B, Biology 20081211

Title: The IsdC protein from Staphylococcus aureus uses a flexible binding pocket to capture heme.

Journal: The Journal of biological chemistry 20081114

Title: Protoporphyrin IX nanoparticle carrier: preparation, optical properties, and singlet oxygen generation.

Journal: Langmuir : the ACS journal of surfaces and colloids 20081104

Title: Melatonin and environmental lighting regulate ALA-S gene expression and So porphyrin biosynthesis in the rat harderian gland.

Journal: Chronobiology international 20081101

Title: [Detection of singlet oxygen and superoxide anion with the fluorescence of FCLA].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20081101

Title: [Two-photon excitation fluorescence of 5-ALA induced PpIX in DHL cells].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20081101

Title: In vivo mitochondrial oxygen tension measured by a delayed fluorescence lifetime technique.

Journal: Biophysical journal 20081015

Title: Sufficient PpIX production for PDT even with short contact time of topically applied 5-ALA in rabbit tongues.

Journal: Lasers in medical science 20081001

Title: A HCl/alcohol formulation increased 5-aminolevulinic acid skin distribution using an ex vivo full thickness porcine skin model.

Journal: Experimental dermatology 20081001

Title: Selective accumulation of PpIX and photodynamic effect after aminolevulinic acid treatment of human adenomyosis xenografts in nude mice.

Journal: Fertility and sterility 20081001

Title: Analysis of differential PDT effect in rat bladder tumor models according to concentrations of intravesical hexyl-aminolevulinate.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080901

Title: Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy.

Journal: Translational research : the journal of laboratory and clinical medicine 20080901

Title: Effects of PDT with 5-aminolevulinic acid and chitosan on Walker carcinosarcoma.

Journal: Experimental oncology 20080901

Title: Metal ion substrate inhibition of ferrochelatase.

Journal: The Journal of biological chemistry 20080829

Title: Microscopic localisation of protoporphyrin IX in normal mouse skin after topical application of 5-aminolevulinic acid or methyl 5-aminolevulinate.

Journal: Journal of photochemistry and photobiology. B, Biology 20080821

Title: Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma.

Journal: Journal of cancer research and clinical oncology 20080801

Title: Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1.

Journal: American journal of respiratory cell and molecular biology 20080801

Title: [Identification of protoporphyrin IX fluorescence spectrum in human blood serum by biorthogonal spline wavelet].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20080801

Title: Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080715

Title: Relationship of protoporphyrin IX synthesis to photodynamic effects by 5-aminolaevulinic acid and its esters on various cell lines derived from the skin.

Journal: The British journal of dermatology 20080701

Title: Protoporphyrin IX fluorescence photobleaching is a useful tool to predict the response of rat ovarian cancer following hexaminolevulinate photodynamic therapy.

Journal: Lasers in surgery and medicine 20080701

Title: Stimulation and inhibition of 5 ALA induced PplX fluorescence in the diagnosis of fibrosarcoma cultivated on the CAM using glucose versus ethanol as modulating agents.

Journal: The Gulf journal of oncology 20080701

Title: 5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy.

Journal: Molecular cancer therapeutics 20080601

Title: Comparison of 5-aminolevulinic acid-encapsulated liposome versus ethosome for skin delivery for photodynamic therapy.

Journal: International journal of pharmaceutics 20080522

Title: Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae.

Journal: Eukaryotic cell 20080501

Title: Substrate-binding model of the chlorophyll biosynthetic magnesium chelatase BchH subunit.

Journal: The Journal of biological chemistry 20080425

Title: Continuous activation of PpIX by daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratoses; a randomized, controlled, single-blinded study.

Journal: The British journal of dermatology 20080401

Title: Glycoside esters of 5-aminolevulinic acid for photodynamic therapy of cancer.

Journal: Bioconjugate chemistry 20080401

Title: Kinetics and subcellular localization of 5-ALA-induced PpIX in DHL cells via two-photon excitation fluorescence microscopy.

Journal: International journal of oncology 20080401

Title: Enhancement of apoptosis by sonodynamic therapy with protoporphyrin IX in isolate sarcoma 180 cells.

Journal: Cancer biotherapy & radiopharmaceuticals 20080401

Title: Resonance energy transfer and ligand binding studies on pH-induced folded states of human serum albumin.

Journal: Journal of photochemistry and photobiology. B, Biology 20080328

Title: 5-aminolevulinic acid induced protoporphyrin IX fluorescence in high-grade glioma surgery: a one-year experience at a single institutuion.

Journal: Swiss medical weekly 20080322

Title: Inhibition of glutathione-S-transferase from Plasmodium yoelii by protoporphyrin IX, cibacron blue and menadione: implications and therapeutic benefits.

Journal: Parasitology research 20080301

Title: Long-pulsed dye laser versus long-pulsed dye laser-assisted photodynamic therapy for acne vulgaris: A randomized controlled trial.

Journal: Journal of the American Academy of Dermatology 20080301

Title: Heme, a plastid-derived regulator of nuclear gene expression in Chlamydomonas.

Journal: The Plant cell 20080301

Title: ALA and its clinical impact, from bench to bedside.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080301

Title: In vivo and in vitro characterisation of a protoporphyrin IX-cyclic RGD peptide conjugate for use in photodynamic therapy.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080301

Title: Apolipoprotein B binds ferritin by hemin-mediated binding: evidence of direct binding of apolipoprotein B and ferritin to hemin.

Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20080201

Title: Silencing of human ferrochelatase causes abundant protoporphyrin-IX accumulation in colon cancer.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201

Title: Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses.

Journal: Archives of dermatological research 20080201

Title: Auditory alert system for fluorescence-guided resection of gliomas.

Journal: Neurologia medico-chirurgica 20080201

Title: Fluorescence kinetics of protoporphyrin-IX induced from 5-ALA compounds in rabbit postballoon injury model for ALA-photoangioplasty.

Journal: Photochemistry and photobiology 20080101

Title: The photosensitizing potential of compact fluorescent vs incandescent light bulbs.

Journal: Photochemistry and photobiology 20080101

Title: Monitoring ALA-induced PpIX photodynamic therapy in the rat esophagus using fluorescence and reflectance spectroscopy.

Journal: Photochemistry and photobiology 20080101

Title: Heme oxygenase-1 attenuates contact hypersensitivity induced by 2,4-dinitrofluorobenzene in mice.

Journal: Immunopharmacology and immunotoxicology 20080101

Title: [Fluorescent diagnostic methods and superficial cancer of the urinary bladder: current status].

Journal: Urologiia (Moscow, Russia : 1999) 20080101

Title: Adenine nucleotide translocator transports haem precursors into mitochondria.

Journal: PloS one 20080101

Title: Nrf2-dependent induction of human ABC transporter ABCG2 and heme oxygenase-1 in HepG2 cells by photoactivation of porphyrins: biochemical implications for cancer cell response to photodynamic therapy.

Journal: Journal of experimental therapeutics & oncology 20080101

Title: [Photodamage to spores of Fusarium fungi, sensitized by protoporphyrin IX].

Journal: Biofizika 20080101

Title: Microscopic distribution of protoporphyrin (PpIX) fluorescence in superficial basal cell carcinoma during light-fractionated aminolaevulinic acid photodynamic therapy.

Journal: Acta dermato-venereologica 20080101

Title: Porphyrin homeostasis maintained by ABCG2 regulates self-renewal of embryonic stem cells.

Journal: PloS one 20080101

Title: Characterization of temperature-dependent iron-imidazole vibrational modes in far infrared.

Journal: The journal of physical chemistry. B 20071227

Title: Sensitivity of osteoblasts, fibroblasts, bone marrow cells, and dendritic cells to 5-aminolevulinic acid based photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20071214

Title: Inhibition of heme oxygenase-1 increases responsiveness of melanoma cells to ALA-based photodynamic therapy.

Journal: International journal of oncology 20071201

Title: Analyzing effects of photodynamic therapy with 5-aminolevulinic acid (ALA) induced protoporphyrin IX (PPIX) in urothelial cells using reverse phase protein arrays.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20071201

Title: Accumulation of protoporphyrin-IX in rat Leydig cells following induction by 5-aminolevulinic acid and tramadol.

Journal: Photomedicine and laser surgery 20071201

Title: Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show the side population (SP) phenotype.

Journal: Immunology letters 20071130

Title: Fluorescence diagnosis in keratinocytic intraepidermal neoplasias.

Journal: Journal of the American Academy of Dermatology 20071101

Title: ['... The better to see you with'--phothodynamic diagnostic in superficial bladder cancer].

Journal: Praxis 20071017

Title: Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling.

Journal: The Journal of biological chemistry 20070928

Title: 5-Aminolevulinic acid-induced protoporphyrin-IX accumulation and associated phototoxicity in macrophages and oral cancer cell lines.

Journal: Journal of photochemistry and photobiology. B, Biology 20070925

Title: Interaction of heme and heme-hemopexin with an extracellular oxidant system used to measure cell growth-associated plasma membrane electron transport.

Journal: Biochimica et biophysica acta 20070901

Title: A mitochondrial protein homologous to the mammalian peripheral-type benzodiazepine receptor is essential for stress adaptation in plants.

Journal: The Plant journal : for cell and molecular biology 20070901

Title: Increased expression of mitochondrial benzodiazepine receptors following low-level light treatment facilitates enhanced protoporphyrin IX production in glioma-derived cells in vitro.

Journal: Lasers in surgery and medicine 20070901

Title: Detection of heme oxygenase activity in a library of four-helix bundle proteins: towards the de novo synthesis of functional heme proteins.

Journal: Journal of molecular biology 20070817

Title: Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid.

Journal: Bioorganic & medicinal chemistry letters 20070815

Title: Cloning and characterization of a novel periplasmic heme-transport protein from the human pathogen Pseudomonas aeruginosa.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801

Title: Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells.

Journal: Experimental dermatology 20070801

Title: Increase in protoporphyrin IX after 5-aminolevulinic acid based photodynamic therapy is due to local re-synthesis.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070801

Title: Comparison of aminolevulinic acid- and hexylester aminolevulinate-induced protoporphyrin IX fluorescence for the detection of ovarian cancer in a rat model.

Journal: Photomedicine and laser surgery 20070801

Title: In vivo quantification of fluorescent molecular markers in real-time by ratio imaging for diagnostic screening and image-guided surgery.

Journal: Lasers in surgery and medicine 20070801

Title: The CHLI1 subunit of Arabidopsis thaliana magnesium chelatase is a target protein of the chloroplast thioredoxin.

Journal: The Journal of biological chemistry 20070706

Title: The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria.

Journal: Cell calcium 20070701

Title: Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy.

Journal: Journal of neuro-oncology 20070701

Title: Photodetection of basal cell carcinoma using methyl 5-aminolaevulinate-induced protoporphyrin IX based on fluorescence image analysis.

Journal: Clinical and experimental dermatology 20070701

Title: Two-photon photodynamic therapy of C6 cells by means of 5-aminolevulinic acid induced protoporphyrin IX.

Journal: Journal of photochemistry and photobiology. B, Biology 20070626

Title: A new dinuclear heme-copper complex derived from functionalized protoporphyrin IX.

Journal: Dalton transactions (Cambridge, England : 2003) 20070607

Title: Expression and simple, one-step purification of fragile histidine triad (Fhit) tumor suppressor mutant forms in Escherichia coli and their interaction with protoporphyrin IX.

Journal: Biotechnology letters 20070601

Title: Impairment of the photosynthetic apparatus by oxidative stress induced by photosensitization reaction of protoporphyrin IX.

Journal: Biochimica et biophysica acta 20070601

Title: Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX.

Journal: Lasers in surgery and medicine 20070601

Title: In vivo visualization of Mg-protoporphyrin IX, a coordinator of photosynthetic gene expression in the nucleus and the chloroplast.

Journal: The Plant cell 20070601

Title: Expression of genes involved in heme biosynthesis in the human retinoblastoma cell lines WERI-Rb-1 and Y79: implications for photodynamic therapy.

Journal: Journal of experimental & clinical cancer research : CR 20070601

Title: Biological activity of 5-aminolevulinic acid and its methyl ester after storage under different conditions.

Journal: Journal of photochemistry and photobiology. B, Biology 20070525

Title: Signals from chloroplasts converge to regulate nuclear gene expression.

Journal: Science (New York, N.Y.) 20070504

Title: Plant science. Signaling to the nucleus with a loaded GUN.

Journal: Science (New York, N.Y.) 20070504

Title: A reporter system for the individual detection of hydrogen peroxide and singlet oxygen: its use for the assay of reactive oxygen species produced in vivo.

Journal: The Plant journal : for cell and molecular biology 20070501

Title: Vitamin D enhances ALA-induced protoporphyrin IX production and photodynamic cell death in 3-D organotypic cultures of keratinocytes.

Journal: The Journal of investigative dermatology 20070401

Title: Limitation of nocturnal import of ATP into Arabidopsis chloroplasts leads to photooxidative damage.

Journal: The Plant journal : for cell and molecular biology 20070401

Title: Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages.

Journal: The American journal of pathology 20070401

Title: Detection of urinary bladder cancer with flow cytometry and hexaminolevulinate in urine samples.

Journal: Cytopathology : official journal of the British Society for Clinical Cytology 20070401

Title: Study of the efficacy and mechanism of ALA-mediated photodynamic therapy on human hepatocellular carcinoma cell.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20070301

Title: Endoscopic identification and biopsy sampling of an intraventricular malignant glioma using a 5-aminolevulinic acid-induced protoporphyrin IX fluorescence imaging system. Technical note.

Journal: Journal of neurosurgery 20070301

Title: The role of nitric oxide in delta-aminolevulinic acid (ALA)-induced photosensitivity of cancerous cells.

Journal: Biochemical and biophysical research communications 20070216

Title: Relation between intracellular location and photodynamic efficacy of 5-aminolevulinic acid-induced protoporphyrin IX in vitro. Comparison between human glioblastoma cells and other cancer cell lines.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070201

Title: Quantitative spectroscopic analysis of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence intensity in diffusely infiltrating astrocytomas.

Journal: Neurologia medico-chirurgica 20070201

Title: Protoporphyrin IX interacts with wild-type p53 protein in vitro and induces cell death of human colon cancer cells in a p53-dependent and -independent manner.

Journal: The Journal of biological chemistry 20070126

Title: Amino acid residues His183 and Glu264 in Bacillus subtilis ferrochelatase direct and facilitate the insertion of metal ion into protoporphyrin IX.

Journal: Biochemistry 20070109

Title: Tumor suppressor Fhit protein interacts with protoporphyrin IX in vitro and enhances the response of HeLa cells to photodynamic therapy.

Journal: Journal of photochemistry and photobiology. B, Biology 20070103

Title: Hexyl-aminolevulinate-mediated photodynamic therapy: how to spare normal urothelium. An in vitro approach.

Journal: Lasers in surgery and medicine 20070101

Title: Proteins of insoluble matrix of avian (gallus gallus) eggshell.

Journal: Connective tissue research 20070101

Title: DNA-directed immobilization of horseradish peroxidase-DNA conjugates on microelectrode arrays: towards electrochemical screening of enzyme libraries.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

Title: In-vivo kinetics of inhaled 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in bronchial tissue.

Journal: Respiratory research 20070101

Title: Photobleaching-based dosimetry predicts deposited dose in ALA-PpIX PDT of rodent esophagus.

Journal: Photochemistry and photobiology 20070101

Title: Direct comparison of delta-aminolevulinic acid and methyl-aminolevulinate-derived protoporphyrin IX accumulations potentiated by desferrioxamine or the novel hydroxypyridinone iron chelator CP94 in cultured human cells.

Journal: Photochemistry and photobiology 20070101

Title: 5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: Cell-substrate topology upon ALA-PDT using variable-angle total internal reflection fluorescence microscopy (VA-TIRFM).

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: ALA and malignant glioma: fluorescence-guided resection and photodynamic treatment.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20070101

Title: Photodynamic therapy of vertebral metastases: evaluating tumor-to-neural tissue uptake of BPD-MA and ALA-PpIX in a murine model of metastatic human breast carcinoma.

Journal: Photochemistry and photobiology 20070101

Title: Study of protoporphyrin IX (PpIX) pharmacokinetics after topical application of 5-aminolevulinic acid in urethral condylomata acuminata.

Journal: Photochemistry and photobiology 20070101

Title: Oxidation decomposition of unsaturated fatty acids by singlet oxygen in phospholipid bilayer membranes.

Journal: Journal of oleo science 20070101

Title: Fluorescence-guided resection of metastatic brain tumors using a 5-aminolevulinic acid-induced protoporphyrin IX: pathological study.

Journal: Brain tumor pathology 20070101

Title: Regulation of 5-aminolevulinic acid-dependent protoporphyrin IX accumulations in human histiocytic lymphoma U937 cells.

Journal: Physiological chemistry and physics and medical NMR 20070101

Title: Photosensitized reduction of water to hydrogen using human serum albumin complexed with zinc-protoporphyrin IX.

Journal: Journal of the American Chemical Society 20061220

Title: Sonodynamic effects of protoporphyrin IX disodium salt on isolated sarcoma 180 cells.

Journal: Ultrasonics 20061201

Title: Fractionated illumination after topical application of 5-aminolevulinic acid on normal skin of hairless mice: the influence of the dark interval.

Journal: Journal of photochemistry and photobiology. B, Biology 20061201

Title: [5-ALA fluorescence guided tumor resection].

Journal: No to shinkei = Brain and nerve 20061201

Title: [Fluorescence diagnosis and photodynamic therapy with 5-aminolevulinic acid induced protoporphyrin IX in gynecology: an overview].

Journal: Zentralblatt fur Gynakologie 20061201

Title: How large is the [Fe(III)(protoporphyrin IX)]+ ion (hemin+) in the gas phase?

Journal: The journal of physical chemistry. B 20061130

Title: Mass spectrometry studies of demetallation of haemin by recombinant horse L chain apoferritin and its mutant (E 53,56,57,60 Q).

Journal: FEBS letters 20061113

Title: Involvement of both caspase-dependent and -independent pathways in apoptotic induction by hexaminolevulinate-mediated photodynamic therapy in human lymphoma cells.

Journal: Apoptosis : an international journal on programmed cell death 20061101

Title: The first structure from the SOUL/HBP family of heme-binding proteins, murine P22HBP.

Journal: The Journal of biological chemistry 20061020

Title: A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts.

Journal: International journal of oncology 20061001

Title: Topical application of 5-aminolaevulinic acid, methyl 5-aminolaevulinate and hexyl 5-aminolaevulinate on normal human skin.

Journal: The British journal of dermatology 20061001

Title: The cytotoxic and genotoxic potential of 5-aminolevulinic acid on lymphocytes: a comet assay study.

Journal: Cancer chemotherapy and pharmacology 20060901

Title: Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines.

Journal: Journal of photochemistry and photobiology. B, Biology 20060901

Title: Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation.

Journal: American journal of physiology. Lung cellular and molecular physiology 20060901

Title: Heterogeneity of fluorescence in psoriasis after application of 5-aminolaevulinic acid: an immunohistochemical study.

Journal: The British journal of dermatology 20060901

Title: Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells.

Journal: British journal of cancer 20060821

Title: Tumor cell lines resistant to ALA-mediated photodynamic therapy and possible tools to target surviving cells.

Journal: International journal of oncology 20060801

Title: A placebo-controlled randomized study on the clinical effectiveness, immunohistochemical changes and protoporphyrin IX accumulation in fractionated 5-aminolaevulinic acid-photodynamic therapy in patients with psoriasis.

Journal: The British journal of dermatology 20060801

Title: Possible role of creatine concentrations in the brain in regulating appetite and weight.

Journal: Brain research 20060726

Title: A new class of [2Fe-2S]-cluster-containing protoporphyrin (IX) ferrochelatases.

Journal: The Biochemical journal 20060701

Title: In vitro phototoxicity of 5-aminolevulinic acid and its methyl ester and the influence of barrier properties on their release from a bioadhesive patch.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060701

Title: Influence of administration methods on the accumulation of ALA-induced Pp-IX in mouse tongue tumors.

Journal: Oral diseases 20060701

Title: Fluorescence staining of human ovarian cancer tissue following application of 5-aminolevulinic acid: fluorescence microscopy studies.

Journal: Lasers in surgery and medicine 20060601

Title: ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells.

Journal: Pharmaceutical research 20060601

Title: The HA2 haemagglutinin domain of the lysine-specific gingipain (Kgp) of Porphyromonas gingivalis promotes micro-oxo bishaem formation from monomeric iron(III) protoporphyrin IX.

Journal: Microbiology (Reading, England) 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Integral spectrophotometric analysis of 5-aminolaevulinic acid-induced fluorescence cytology of the urinary bladder.

Journal: BJU international 20060501

Title: Nitric oxide-induced resistance to lethal photooxidative damage in a breast tumor cell line.

Journal: Free radical biology & medicine 20060415

Title: Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.

Journal: Journal of photochemistry and photobiology. B, Biology 20060403

Title: In vitro percutaneous absorption and in vivo protoporphyrin IX accumulation in skin and tumors after topical 5-aminolevulinic acid application with enhancement using an erbium:YAG laser.

Journal: Journal of pharmaceutical sciences 20060401

Title: Characteristics of 5-aminolaevulinic acid-induced protoporphyrin IX fluorescence in human skin in vivo.

Journal: Photodermatology, photoimmunology & photomedicine 20060401

Title: Griseofulvin enhances the effect of aminolevulinic acid-based photodynamic therapy in vitro.

Journal: Photomedicine and laser surgery 20060401

Title: Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: potential agents for photodynamic therapy of cancers.

Journal: Bioorganic & medicinal chemistry 20060301

Title: Three-dimensional model of the human aromatase enzyme and density functional parameterization of the iron-containing protoporphyrin IX for a molecular dynamics study of heme-cysteinato cytochromes.

Journal: Proteins 20060301

Title: Role of vascular heme oxygenase in reduced myogenic reactivity following chronic hypoxia.

Journal: Microcirculation (New York, N.Y. : 1994) 20060301

Title: A direct and simultaneous detection of zinc protoporphyrin IX, free protoporphyrin IX, and fluorescent heme degradation product in red blood cell hemolysates.

Journal: Free radical research 20060301

Title: YC-1-like potentiation of NO-dependent activation of soluble guanylate cyclase by derivatives of protoporphyrin IX.

Journal: Biochemistry. Biokhimiia 20060301

Title: Arabidopsis ACCELERATED CELL DEATH2 modulates programmed cell death.

Journal: The Plant cell 20060201

Title: Inhibitory effect of piperlonguminine on melanin production in melanoma B16 cell line by downregulation of tyrosinase expression.

Journal: Pigment cell research 20060201

Title: Non-covalent modification of the heme-pocket of apomyoglobin by a 1,10-phenanthroline derivative.

Journal: Bioorganic & medicinal chemistry letters 20060115

Title: The pH-dependent conformational transition of beta-lactoglobulin modulates the binding of protoporphyrin IX.

Journal: Biochimica et biophysica acta 20060101

Title: Photobleaching kinetics, photoproduct formation, and dose estimation during ALA induced PpIX PDT of MLL cells under well oxygenated and hypoxic conditions.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060101

Title: Topical bioadhesive patch systems enhance selectivity of protoporphyrin IX accumulation.

Journal: Photochemistry and photobiology 20060101

Title: Use of ALA and ALA derivatives for optimizing ALA-based photodynamic therapy: a review of our experience.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: Regulation of porphyrin synthesis and photodynamic therapy in heavy metal intoxication.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: Repetitive photodynamic therapy of malignant brain tumors.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: Spectroscopic measurements of photoinduced processes in human skin after topical application of the hexyl ester of 5-aminolevulinic acid.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: Photodynamic therapy of nodular basal cell carcinoma with multifiber contact light delivery.

Journal: Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20060101

Title: Targeting of sebocytes by aminolevulinic acid-dependent photosensitization.

Journal: Photochemistry and photobiology 20060101

Title: Protoporphyrin IX level correlates with number of mitochondria, but increase in production correlates with tumor cell size.

Journal: Photochemistry and photobiology 20060101

Title: beta-Carotene and cigarette smoke condensate regulate heme oxygenase-1 and its repressor factor Bach1: relationship with cell growth.

Journal: Antioxidants & redox signaling 20060101

Title: Photodynamic therapies: principles and present medical applications.

Journal: Bio-medical materials and engineering 20060101

Title: Protoporphyrin IX fluorescence photobleaching and the response of rat Barrett's esophagus following 5-aminolevulinic acid photodynamic therapy.

Journal: Photochemistry and photobiology 20060101

Title: Topical 5-aminolevulinic acid mediated photodynamic therapy of superficial basal cell carcinoma using two light fractions with a two-hour interval: long-term follow-up.

Journal: Acta dermato-venereologica 20060101

Title: On the role of iron and one of its chelating agents in the production of protoporphyrin IX generated by 5-aminolevulinic acid and its hexyl ester derivative tested on an epidermal equivalent of human skin.

Journal: Photochemistry and photobiology 20060101

Title: Photodynamic diagnosis (PDD) using 5-aminolevulinic acid-supplemented cultures of human endometrial epithelial cells.

Journal: Advances in medical sciences 20060101

Title: Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells.

Journal: Human molecular genetics 20051215

Title: Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells.

Journal: Cancer research 20051201

Title: Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation.

Journal: British journal of cancer 20051114

Title: Functional characterization of the C-terminal domain of the cytochrome c maturation protein CcmE.

Journal: The Journal of biological chemistry 20051104

Title: Expression pattern and intensity of protoporphyrin IX induced by liposomal 5-aminolevulinic acid in rat pilosebaceous unit throughout hair cycle.

Journal: Archives of dermatological research 20051101

Title: Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester.

Journal: The Journal of investigative dermatology 20051101

Title: In vitro and ex vivo protoporphyrin IX expression induced by 5-aminolevulinic acid in human pilosebaceous unit.

Journal: Journal of dermatological science 20051001

Title: Induction of apoptosis-like mitochondrial impairment triggers antioxidant and Bcl-2-dependent keratinocyte differentiation.

Journal: The Journal of investigative dermatology 20051001

Title: Correlation between macroscopic fluorescence and protoporphyrin IX content in psoriasis and actinic keratosis following application of aminolevulinic acid.

Journal: The Journal of investigative dermatology 20051001

Title: Lack of effect of hyperoxia on photodynamic therapy and lipid peroxidation in three different cancer cell lines.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20051001

Title: Lipid cubic phases for improved topical drug delivery in photodynamic therapy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20050902

Title: Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells.

Journal: American journal of physiology. Cell physiology 20050901

Title: A continuous fluorimetric assay for protoporphyrinogen oxidase by monitoring porphyrin accumulation.

Journal: Analytical biochemistry 20050901

Title: [Intraoperative photodynamic diagnosis using 5-ALA for glioma surgery].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901

Title: Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2.

Journal: Blood 20050801

Title: Topical glycerol monooleate/propylene glycol formulations enhance 5-aminolevulinic acid in vitro skin delivery and in vivo protophorphyrin IX accumulation in hairless mouse skin.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050801

Title: Metalloporphyrins inactivate caspase-3 and -8.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801

Title: Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system.

Journal: Chemistry & biology 20050801

Title: Photodynamic therapy of Walker tumors by multiple laser irradiation.

Journal: Photomedicine and laser surgery 20050801

Title: Size and surface charge effect of 5-aminolevulinic acid-containing liposomes on photodynamic therapy for cultivated cancer cells.

Journal: Drug development and industrial pharmacy 20050801

Title: Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia.

Journal: International journal of oncology 20050701

Title: Reorganization of cytoskeleton induced by 5-aminolevulinic acid-mediated photodynamic therapy and its correlation with mitochondrial dysfunction.

Journal: Lasers in surgery and medicine 20050601

Title: Topical application of photofrin for photodynamic diagnosis of oral neoplasms.

Journal: Plastic and reconstructive surgery 20050601

Title: Residues stabilizing the heme moiety of the nitric oxide sensor soluble guanylate cyclase.

Journal: European journal of pharmacology 20050418

Title: The final catalytic step of cytochrome p450 aromatase: a density functional theory study.

Journal: Journal of the American Chemical Society 20050413

Title: Light scattering from intact cells reports oxidative-stress-induced mitochondrial swelling.

Journal: Biophysical journal 20050401

Title: Cell specific effects of polyunsaturated fatty acids on 5-aminolevulinic acid based photosensitization.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050401

Title: RNA expression profiling of normal and tumor cells following photodynamic therapy with 5-aminolevulinic acid-induced protoporphyrin IX in vitro.

Journal: Molecular cancer therapeutics 20050401

Title: Porphyrin-substrate binding to murine ferrochelatase: effect on the thermal stability of the enzyme.

Journal: The Biochemical journal 20050315

Title: Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels.

Journal: Blood 20050315

Title: Antifungal effect of 5-aminolevulinic acid PDT in Trichophyton rubrum.

Journal: Mycoses 20050301

Title: Formation of a misfolded conformation during refolding of HRPA1 in the presence of calcium.

Journal: Biochimica et biophysica acta 20050214

Title: ABCG2-mediated transport of photosensitizers: potential impact on photodynamic therapy.

Journal: Cancer biology & therapy 20050201

Title: Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester.

Journal: Photochemistry and photobiology 20050101

Title: Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis.

Journal: Laboratory investigation; a journal of technical methods and pathology 20050101

Title: Self-sensitized photodegradation of membrane-bound protoporphyrin mediated by chain lipid peroxidation: inhibition by nitric oxide with sustained singlet oxygen damage.

Journal: Photochemistry and photobiology 20050101

Title: Specific intensity imaging for glioblastoma and neural cell cultures with 5-aminolevulinic acid-derived protoporphyrin IX.

Journal: Journal of neuro-oncology 20050101

Title: A spectrophotometric micromethod for determining erythrocyte protoporphyrin-IX in whole blood or erythrocytes.

Journal: Clinical chemistry and laboratory medicine 20050101

Title: Systemic suppression of the contact hypersensitivity by the products of protoporphyrin IX photooxidation.

Journal: Photochemistry and photobiology 20050101

Title: [The role of lipid peroxidation products in the effect of He-Ne laser on human blood leukocytes].

Journal: Biofizika 20050101

Title: Inner-sphere electron-transfer reorganization energies of zinc porphyrins.

Journal: Journal of the American Chemical Society 20041201

Title: In vitro metabolism of 5-ALA esters derivatives in hairless mice skin homogenate and in vivo PpIX accumulation studies.

Journal: Pharmaceutical research 20041201

Title: Effect of oil-in-water emulsions on 5-aminolevulinic acid uptake and metabolism to PpIX in cultured MCF-7 cells.

Journal: Pharmaceutical research 20041201

Title: [Fluorescence imaging technique: diagnostic and therapeutic interest in gynecology].

Journal: Journal de gynecologie, obstetrique et biologie de la reproduction 20041201

Title: RRM analysis of protoporphyrinogen oxidase.

Journal: Australasian physical & engineering sciences in medicine 20041201

Title: The mitochondrion--an organelle commonly involved in programmed cell death in Arabidopsis thaliana.

Journal: The Plant journal : for cell and molecular biology 20041101

Title: In vitro studies on thioether bond formation between Hydrogenobacter thermophilus apocytochrome c(552) with metalloprotoporphyrin derivatives.

Journal: The Journal of biological chemistry 20041029

Title: Crystal structure of arachidonic acid bound to a mutant of prostaglandin endoperoxide H synthase-1 that forms predominantly 11-hydroperoxyeicosatetraenoic acid.

Journal: The Journal of biological chemistry 20041008

Title: Optimised expression and purification of recombinant human indoleamine 2,3-dioxygenase.

Journal: Protein expression and purification 20041001

Title: Phototoxicity of exogenous protoporphyrin IX and delta-aminolevulinic acid in the photo hen's egg test.

Journal: Photodermatology, photoimmunology & photomedicine 20041001

Title: Phototoxicity of 5-aminolevulinic acid in the HeLa cell line as an indicative measure of photodynamic effect after topical administration to gynecological lesions of intraepithelial form.

Journal: Pharmaceutical research 20041001

Title: The monitoring of the accumulation of protoporphyrin IX in Walker tumours by subcutaneous administration of delta-aminolevulinic acid.

Journal: Journal of experimental therapeutics & oncology 20041001

Title: Photosensitization with protoporphyrin IX inhibits attachment of cancer cells to a substratum.

Journal: Biochemical and biophysical research communications 20040917

Title: Synthesis and photochemical properties of a novel iron-sulfur-nitrosyl cluster derivatized with the pendant chromophore protoporphyrin IX.

Journal: Inorganic chemistry 20040906

Title: Mechanism of internal anal sphincter relaxation by CORM-1, authentic CO, and NANC nerve stimulation.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20040901

Title: Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study.

Journal: Gastrointestinal endoscopy 20040901

Title: Mechanism of in vitro heme-induced LDL oxidation: effects of antioxidants.

Journal: European journal of clinical investigation 20040901

Title: Confocal endomicroscopic imaging of normal and neoplastic human tongue tissue using ALA-induced-PPIX fluorescence: a preliminary study.

Journal: Oncology reports 20040801

Title: delta-Aminolaevulinic acid mediated photodynamic antimicrobial chemotherapy on Pseudomonas aeruginosa planktonic and biofilm cultures.

Journal: Journal of photochemistry and photobiology. B, Biology 20040719

Title: Crystal structure of the ascorbate peroxidase-salicylhydroxamic acid complex.

Journal: Biochemistry 20040713

Title: In vitro evaluation of the cytotoxic and mutagenic potential of the 5-aminolevulinic acid hexylester-mediated photodynamic therapy.

Journal: Mutation research 20040711

Title: Mapping ALA-induced PPIX fluorescence in normal brain and brain tumour using confocal fluorescence microscopy.

Journal: International journal of oncology 20040701

Title: The use of digitized endoscopic imaging of 5-ALA-induced PPIX fluorescence to detect and diagnose oral premalignant and malignant lesions in vivo.

Journal: International journal of cancer 20040610

Title: Proximal and distal influences on ligand binding kinetics in microperoxidase and heme model compounds.

Journal: Biochemistry 20040608

Title: The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme.

Journal: The Journal of biological chemistry 20040604

Title: Fluorescence diagnosis: a novel method to guide radical inguinal lymph node dissection in penile cancer.

Journal: World journal of urology 20040601

Title: Influence of CaNa2 EDTA on topical 5-aminolaevulinic acid photodynamic therapy.

Journal: Chinese medical journal 20040601

Title: A novel Arabidopsis thaliana protein is a functional peripheral-type benzodiazepine receptor.

Journal: Plant & cell physiology 20040601

Title: Characterization of eight barley xantha-f mutants deficient in magnesium chelatase.

Journal: Plant physiology and biochemistry : PPB 20040601

Title: 5-aminolevulinic acid-based photodynamic therapy in leukemia cell HL60.

Journal: Photochemistry and photobiology 20040601

Title: Differentiation-dependent photodynamic therapy regulated by porphobilinogen deaminase in B16 melanoma.

Journal: British journal of cancer 20040504

Title: ALA (5-aminolevulinic acid)-induced protoporphyrin IX fluorescence in the endoscopic diagnostic and control of pharyngo-laryngeal cancer.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20040501

Title: Heme-iron increases levels of AP65-mediated adherence by Trichomonas vaginalis.

Journal: Microbial pathogenesis 20040501

Title: On the selectivity of 5-aminolevulinic acid-induced protoporphyrin IX formation.

Journal: Current medicinal chemistry. Anti-cancer agents 20040501

Title: Laparoscopic fluorescence detection of ovarian carcinoma metastases using 5-aminolevulinic acid-induced protoporphyrin IX.

Journal: Cancer 20040415

Title: Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus.

Journal: Surgical endoscopy 20040301

Title: Effect of elevating the skin temperature during topical ALA application on in vitro ALA penetration through mouse skin and in vivo PpIX production in human skin.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040301

Title: Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum.

Journal: Biochimica et biophysica acta 20040105

Title: In situ assessment of porphyrin photosensitizers in Propionibacterium acnes.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Title: Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - in vivo experiments on the dunning rat tumor model.

Journal: Urologia internationalis 20040101

Title: Effect of 5-aminolevulinic acid on kinetics of protoporphyrin IX production in CHO cells.

Journal: Folia histochemica et cytobiologica 20040101

Title: 5-aminolevulinic acid ester-induced protoporphyrin IX in a murine melanoma cell line.

Journal: Lasers in medical science 20040101

Title: [5-Aminolevulinic acid (ALA) and its applications in neurosurgery].

Journal: Neurologia i neurochirurgia polska 20040101

Title: Increased brain tumor resection using fluorescence image guidance in a preclinical model.

Journal: Lasers in surgery and medicine 20040101

Title: Time-dependent hexaminolaevulinate induced protoporphyrin IX distribution after topical application in patients with cervical intraepithelial neoplasia: A fluorescence microscopy study.

Journal: Lasers in surgery and medicine 20040101

Title: Heme oxygenase-2 products activate IKCa: role of CO and iron in guinea pig portal vein smooth muscle cells.

Journal: Journal of muscle research and cell motility 20040101

Title: Erythrocytes-the 'house elves' of photodynamic therapy.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040101

Title: Phototoxicity of protoporphyrin IX, diarginine diprotoporphyrinate and N,N-diphenylalanyl protoporphyrin toward human fibroblasts and keratinocytes in vitro: effect of 5-methoxypsoralen.

Journal: Photochemistry and photobiology 20040101

Title: Effect of 5-aminolevulinic acid (ALA) doses and oestrogen/progesterone on protoporphyrin IX (ppIX) accumulation in human endometrial epithelial cells.

Journal: Roczniki Akademii Medycznej w Bialymstoku (1995) 20040101

Title: Protoporphyrin IX-accumulation in human tumor cells following topical ALA- and h-ALA-application in vivo.

Journal: Cancer letters 20031208

Title: Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire.

Journal: Current protein & peptide science 20031201

Title: Protoporphyrin IX binding and transport by recombinant mouse PBR.

Journal: Biochemical and biophysical research communications 20031128

Title: In vitro tests of the validity of singlet oxygen luminescence measurements as a dose metric in photodynamic therapy.

Journal: Cancer research 20031115

Title: In vivo fluorescence kinetics and photodynamic therapy in condylomata acuminata.

Journal: The British journal of dermatology 20031101

Title: Protoporphyrin IX production and its photodynamic effects on glioma cells, neuroblastoma cells and normal cerebellar granule cells in vitro with 5-aminolevulinic acid and its hexylester.

Journal: Cancer letters 20031028

Title: A physiological role for protoporphyrin IX photodynamic action in the rat Harderian gland?

Journal: Acta physiologica Scandinavica 20031001

Title: [Precancerous conditions in the urothelium. Early detection and molecular understanding through endoscopic fluorescence diagnosis].

Journal: Der Pathologe 20031001

Title: Preparation of heme-free soluble guanylate cyclase.

Journal: Protein expression and purification 20030901

Title: Metalloporphyrin probes for antimalarial drug action.

Journal: Journal of inorganic biochemistry 20030901

Title: Monitoring in situ dosimetry and protoporphyrin IX fluorescence photobleaching in the normal rat esophagus during 5-aminolevulinic acid photodynamic therapy.

Journal: Photochemistry and photobiology 20030901

Title: Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma.

Journal: British journal of cancer 20030818

Title: Hemoglobin metabolites mimic benzodiazepines and are possible mediators of hepatic encephalopathy.

Journal: Blood 20030815

Title: Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer.

Journal: The Journal of urology 20030801

Title: Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.

Journal: Endoscopy 20030801

Title: Comparative antistreptococcal activity of photobactericidal agents.

Journal: Journal of chemotherapy (Florence, Italy) 20030801

Title: Coordination complex between haemin and parallel-quadruplexed d(TTAGGG).

Journal: Chemical communications (Cambridge, England) 20030721

Title: Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation.

Journal: Gut 20030701

Title: Repeated exposure to blue light does not improve psoriasis.

Journal: Journal of the American Academy of Dermatology 20030701

Title: Photodynamic effects of 5-aminolevulinic acid and its hexylester on several cell lines.

Journal: Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030701

Title: The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical 5-aminolaevulinic acid photodynamic therapy.

Journal: The British journal of dermatology 20030701

Title: Aminolaevulinic acid-induced protoporphyrin IX pharmacokinetics in central and peripheral arteries of the rat.

Journal: Photochemistry and photobiology 20030701

Title: Specificity of photosensitizer accumulation in undifferentiated versus differentiated colon carcinoma cells.

Journal: Cancer letters 20030630

Title: Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study.

Journal: British journal of cancer 20030602

Title: Biosynthesis of chlorophylls from protoporphyrin IX.

Journal: Natural product reports 20030601

Title: Fluorescence microspectroscopy technique for the study of intracellular protoporphyrin IX dynamics.

Journal: Applied spectroscopy 20030601

Title: Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial.

Journal: Neurology 20030527

Title: Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring.

Journal: Neurology 20030527

Title: Evaluation of dipeptide-derivatives of 5-aminolevulinic acid as precursors for photosensitizers in photodynamic therapy.

Journal: Bioorganic & medicinal chemistry 20030403

Title: A randomised, double-blind, placebo-controlled trial of photodynamic therapy using 5-aminolaevulinic acid for the treatment of cervical intraepithelial neoplasia.

Journal: International journal of cancer 20030301

Title: Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid.

Journal: International journal of oncology 20030301

Title: Dose and timing of the first light fraction in two-fold illumination schemes for topical ALA-mediated photodynamic therapy of hairless mouse skin.

Journal: Photochemistry and photobiology 20030301

Title: GUN4, a regulator of chlorophyll synthesis and intracellular signaling.

Journal: Science (New York, N.Y.) 20030207

Title: High-resolution structure and biochemical properties of a recombinant Proteus mirabilis catalase depleted in iron.

Journal: Proteins 20030201

Title: Comparison of the formation of N-alkylprotoporphyrin IX after interaction of porphyrinogenic xenobiotics with single cDNA-expressed human P450 enzymes in microsomes prepared from baculovirus-infected insect cells and human lymphoblastoid cell lines.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030201

Title: A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer.

Journal: International journal of oncology 20030201

Title: The importance of porphyrin distortions for the ferrochelatase reaction.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030201

Title: Phototoxic effects of 635-nm light on canine transitional cell carcinoma cells incubated with 5-aminolevulinic acid.

Journal: American journal of veterinary research 20030201

Title: Chloroplast to nucleus communication triggered by accumulation of Mg-protoporphyrinIX.

Journal: Nature 20030102

Title: Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters.

Journal: International journal of cancer 20030101

Title: Time gated fluorescence spectroscopy in Barrett's oesophagus.

Journal: Gut 20030101

Title: Time-resolved microspectrofluorometry and fluorescence lifetime imaging of photosensitizers using picosecond pulsed diode lasers in laser scanning microscopes.

Journal: Journal of biomedical optics 20030101

Title: Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.

Journal: Lasers in surgery and medicine 20030101

Title: A spectroscopic study of the photobleaching of protoporphyrin IX in solution.

Journal: Lasers in medical science 20030101

Title: [Photodynamic damage of yeast subcellular fraction induced by elevated levels of endogenous protoporphyrin IX].

Journal: Mikrobiologiia 20030101

Title: Fluorescence-guided resections of malignant gliomas--an overview.

Journal: Acta neurochirurgica. Supplement 20030101

Title: Detection of protoporphyrin IX in envelope membranes of pea chloroplasts.

Journal: Biochemical and biophysical research communications 20021220

Title: Protoporphyrin-IX accumulation and cutaneous tumor regression in mice using a ferrochelatase inhibitor.

Journal: Cancer letters 20021210

Title: Gene expression pattern following photodynamic treatment of the carcinoma cell line A-431 analysed by cDNA arrays.

Journal: International journal of oncology 20021201

Title: Effects on free radical generation by ligands of the peripheral benzodiazepine receptor in cultured neural cells.

Journal: Journal of neurochemistry 20021201

Title: Porphyrins as early biomarkers for arsenic exposure in animals and humans.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20021201

Title: Bilirubin and ferritin as protectors against hemin-induced oxidative stress in rat liver.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20021201

Title: Two course illuminating scheme improves aminolevulinic acid photodynamic therapy in cell cultures.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20021201

Title: Production of protoporphyrin IX from 5-aminolevulinic acid and two of its esters in cells in vitro and tissues in vivo.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20021201

Title: Improving the use of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PPIX) for the gastrointestinal tract by esterification--an in vitro study.

Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20021201

Title: Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells.

Journal: British journal of cancer 20021118

Title: Hyperresistance to photosensitized lipid peroxidation and apoptotic killing in 5-aminolevulinate-treated tumor cells overexpressing mitochondrial GPX4.

Journal: Free radical biology & medicine 20021115

Title: [Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid].

Journal: Laryngo- rhino- otologie 20021101

Title: Metabolic characterization of tumor cell-specific protoporphyrin IX accumulation after exposure to 5-aminolevulinic acid in human colonic cells.

Journal: Photochemistry and photobiology 20021101

Title: Transfer of protoporphyrin IX between cells.

Journal: Photochemistry and photobiology 20021101

Title: Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes.

Journal: Photochemistry and photobiology 20021101

Title: Detection of neoplasms in the oral cavity by digitized endoscopic imaging of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.

Journal: International journal of oncology 20021001

Title: Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.

Journal: Gastrointestinal endoscopy 20021001

Title: Temperature effect on accumulation of protoporphyrin IX after topical application of 5-aminolevulinic acid and its methylester and hexylester derivatives in normal mouse skin.

Journal: Photochemistry and photobiology 20021001

Title: Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021001

Title: Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice.

Journal: Biochemical and biophysical research communications 20020927

Title: Comparison of 5-aminolevulinic acid and its hexylester mediated photodynamic action on human hepatoma cells.

Journal: Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20020901

Title: Topical application of 5-aminolevulinic acid and its methylester, hexylester and octylester derivatives: considerations for dosimetry in mouse skin model.

Journal: Photochemistry and photobiology 20020901

Title: Enhanced transdermal transport by electroporation using anionic lipids.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20020821

Title: Timing of 5-aminolaevulinic acid-induced photodynamic therapy for the treatment of patients with Barrett's oesophagus.

Journal: Journal of photochemistry and photobiology. B, Biology 20020801

Title: Effect of prostaglandin-J(2) on VEGF synthesis depends on the induction of heme oxygenase-1.

Journal: Antioxidants & redox signaling 20020801

Title: Porphyrin accumulation induced by 5-aminolaevulinic acid esters in tumour cells growing in vitro and in vivo.

Journal: British journal of cancer 20020715

Title: Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice.

Journal: Archives of dermatological research 20020701

Title: In vivo pharmacokinetics of 8-aminolevulinic acid-induced protoporphyrin IX during pre- and post-photodynamic therapy in 7,12-dimethylbenz(a)nthracene-treated skin carcinogenesis in Swiss mice: a comparison by three-compartment model.

Journal: Photochemistry and photobiology 20020701

Title: Systemic photodynamic therapy with aminolevulinic acid induces apoptosis in lesional T lymphocytes of psoriatic plaques.

Journal: The Journal of investigative dermatology 20020701

Title: PDT effects of m-THPC and ALA, phototoxicity and apoptosis.

Journal: Apoptosis : an international journal on programmed cell death 20020601

Title: Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.

Journal: European journal of gastroenterology & hepatology 20020601

Title: Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.

Journal: Blood 20020515

Title: Clinical pharmacokinetics of 5-aminolevulinic acid in healthy volunteers and patients at high risk for recurrent bladder cancer.

Journal: The Journal of pharmacology and experimental therapeutics 20020501

Title: In vitro/in vivo correlations between transdermal delivery of 5-aminolaevulinic acid and cutaneous protoporphyrin IX accumulation and effect of formulation.

Journal: The British journal of dermatology 20020501

Title: Protoporphyrin IX fluorescence kinetics in UV-induced tumours and normal skin of hairless mice after topical application of 5-aminolevulinic acid methyl ester.

Journal: Journal of photochemistry and photobiology. B, Biology 20020501

Title: Tumor PO(2) changes during photodynamic therapy depend upon photosensitizer type and time after injection.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20020501

Title: Protoporphyrin IX photodynamic therapy for synovitis.

Journal: Arthritis and rheumatism 20020501

Title: In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid.

Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020501

Title: Aminolaevulinic acid-induced photodynamic therapy: cellular responses to glucose starvation.

Journal: British journal of cancer 20020422

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Histidine pK(a) shifts and changes of tautomeric states induced by the binding of gallium-protoporphyrin IX in the hemophore HasA(SM).

Journal: Protein science : a publication of the Protein Society 20020401

Title: The fluorescence biodistribution and kinetics of aminolevulinic acid induced protoporphyrin IX in the bladder of a rat model with orthotopic urothelial carcinoma.

Journal: The Journal of urology 20020401

Title: Detection of female lower genital tract dysplasia using orally administered 5-aminolevulinic acid induced protoporphyrin IX: a preliminary study.

Journal: Gynecologic oncology 20020401

Title: Localization and staging of cervical intraepithelial neoplasia using double ratio fluorescence imaging.

Journal: Journal of biomedical optics 20020401

Title: Quantitative model calculation of the time-dependent protoporphyrin IX concentration in normal human epidermis after delivery of ALA by passive topical application or lontophoresis.

Journal: Photochemistry and photobiology 20020401

Title: Effects of porphyrins and inorganic iron on the growth of Prevotella intermedia.

Journal: FEMS microbiology letters 20020319

Title: The atomic structure of human methemalbumin at 1.9 A.

Journal: Biochemical and biophysical research communications 20020308

Title: Asp-225 and glu-375 in autocatalytic attachment of the prosthetic heme group of lactoperoxidase.

Journal: The Journal of biological chemistry 20020301

Title: Antitumor agents. Part 209: Pheophorbide-a derivatives as photo-Independent cytotoxic agents.

Journal: Bioorganic & medicinal chemistry 20020301

Title: Measurement of ferrochelatase activity using a novel assay suggests that plastids are the major site of haem biosynthesis in both photosynthetic and non-photosynthetic cells of pea (Pisum sativum L.).

Journal: The Biochemical journal 20020301

Title: Inhibition of nitric oxide-dependent activation of soluble guanylyl cyclase by the antimalarial drug, artemisinin.

Journal: European journal of pharmacology 20020301

Title: Laparoscopic fluorescence diagnosis for intraabdominal fluorescence targeting of peritoneal carcinosis experimental studies.

Journal: Annals of surgery 20020201

Title: PpIX fluorescence kinetics and increased skin damage after intracutaneous injection of 5-aminolevulinic acid and repeated illumination.

Journal: The Journal of investigative dermatology 20020201

Title: Potential efficacy of a delta 5-aminolevulinic acid thermosetting gel formulation for use in photodynamic therapy of lesions of the gastrointestinal tract.

Journal: Pharmacological research 20020201

Title: Systemic component of protoporphyrin IX production in nude mouse skin upon topical application of aminolevulinic acid depends on the application conditions.

Journal: Photochemistry and photobiology 20020201

Title: A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis.

Journal: International journal of cancer 20020110

Title: The influence of photodynamic reaction on R2C cells.

Journal: Folia histochemica et cytobiologica 20020101

Title: Amino acid and peptide conjugates of protoporphyrin: preparation and analysis by high-performance liquid chromatography, high-performance liquid chromatography/electrospray ionization mass spectrometry and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20020101

Title: Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor.

Journal: Respiration; international review of thoracic diseases 20020101

Title: Porphyrinogenic xenobiotic-induced N-alkylprotoporphyrin IX formation: a bioassay utilizing chick embryo hepatic ferrochelatase.

Journal: Journal of pharmacological and toxicological methods 20020101

Title: [Fluorescent photobleaching of endogenous protoporphyrin IX in yeast cells].

Journal: Biofizika 20020101

Title: Comparison of normal piglet bladder damage after PDT with oral or intravesical administration of ALA.

Journal: Lasers in medical science 20020101

Title: Antioxidant inhibition of porphyrin-induced cellular phototoxicity.

Journal: Journal of photochemistry and photobiology. B, Biology 20011231

Title: Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency.

Journal: The EMBO journal 20011203

Title: The influence of UV exposure on 5-aminolevulinic acid-induced protoporphyrin IX production in skin.

Journal: Photochemistry and photobiology 20011201

Title: Intraoperative fluorescence visualization of the parathyroid gland in rats.

Journal: Endocrinology 20011101

Title: Fluorescence induced with 5-aminolevulinic acid for the endoscopic detection and follow-up of esophageal lesions.

Journal: Gastrointestinal endoscopy 20011101

Title: Effects of 5-aminolaevulinic acid on human ovarian cancer cells and human vascular endothelial cells in vitro.

Journal: Journal of photochemistry and photobiology. B, Biology 20011101

Title: Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon.

Journal: British journal of cancer 20011101

Title: The effects of 5-aminolevulinic acid esters on protoporphyrin IX production in human adenocarcinoma cell lines.

Journal: Photochemistry and photobiology 20011101

Title: ALA and ALA hexyl ester-induced porphyrin synthesis in chemically induced skin tumours: the role of different vehicles on improving photosensitization.

Journal: British journal of cancer 20011101

Title: [Intraoperative photodynamic diagnosis of human glioma using ALA induced protoporphyrin IX].

Journal: No shinkei geka. Neurological surgery 20011101

Title: In vitro and in vivo expression of protoporphyrin IX induced by lipophilic 5-aminolevulinic acid derivatives.

Journal: Journal of dermatological science 20011001

Title: Photodynamic effects induced by aminolevulinic acid esters on human cervical carcinoma cells in culture.

Journal: Photochemistry and photobiology 20011001

Title: Isolation and characterization of a cDNA from soybean and its homolog from Escherichia coli, which both complement the light sensitivity of Escherichia coli hemH mutant strain VS101.

Journal: Genes & genetic systems 20011001

Title: ALA- and ALA-hexylester-induced protoporphyrin IX fluorescence and distribution in multicell tumour spheroids.

Journal: British journal of cancer 20010901

Title: Autofluorescence imaging to optimize 5-ALA-induced fluorescence endoscopy of bladder carcinoma.

Journal: Urology 20010901

Title: Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms.

Journal: Journal of endourology 20010901

Title: In vivo pharmacokinetics of protoporphyrin IX accumulation following intracutaneous injection of 5-aminolevulinic acid.

Journal: Journal of photochemistry and photobiology. B, Biology 20010815

Title: Fluorescence spectroscopy of normal mouse skin exposed to 5-aminolaevulinic acid and red light.

Journal: Journal of photochemistry and photobiology. B, Biology 20010815

Title: Evaluation of protoporphyrin IX production, phototoxicity and cell death pathway induced by hexylester of 5-aminolevulinic acid in Reh and HPB-ALL cells.

Journal: Cancer letters 20010810

Title: 5-Aminolevulinic acid-based photochemical internalization of the immunotoxin MOC31-gelonin generates synergistic cytotoxic effects in vitro.

Journal: Photochemistry and photobiology 20010801

Title: A mathematical evaluation of dose-dependent PpIX fluorescence kinetics in vivo.

Journal: Photochemistry and photobiology 20010801

Title: Oral aminolevulinic acid induces protoporphyrin IX fluorescence in psoriatic plaques and peripheral blood cells.

Journal: Photochemistry and photobiology 20010801

Title: The role of the peripheral benzodiazepine receptor in the apoptotic response to photodynamic therapy.

Journal: Photochemistry and photobiology 20010801

Title: Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs.

Journal: Antioxidants & redox signaling 20010801

Title: 5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells.

Journal: Journal of photochemistry and photobiology. B, Biology 20010701

Title: The photosensitizing effect of the photoproduct of protoporphyrin IX.

Journal: Journal of photochemistry and photobiology. B, Biology 20010701

Title: Optimization of differential photodynamic effectiveness between normal and tumor urothelial cells using 5-aminolevulinic acid-induced protoporphyrin IX as sensitizer.

Journal: International journal of cancer 20010601

Title: Relaxometric characterization of human hemalbumin.

Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010601

Title: Substitution of murine ferrochelatase glutamate-287 with glutamine or alanine leads to porphyrin substrate-bound variants.

Journal: The Biochemical journal 20010515

Title: Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010515

Title: Evaluation on the adsorption capabilities of new chemically modified polymeric adsorbents with protoporphyrin IX.

Journal: Journal of chromatography. A 20010511

Title: Photodynamic DNA damage mediated by delta-aminolevulinic acid-induced porphyrins.

Journal: Carcinogenesis 20010501

Title: Photomodification of the electrical properties of the plasma membrane: a comparison between 6 different membrane-active photosensitizers.

Journal: The Journal of membrane biology 20010501

Title: A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester.

Journal: The British journal of dermatology 20010501

Title: On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters.

Journal: International journal of cancer 20010401

Title: Synergistic toxicity of delta-aminolaevulinic acid-induced protoporphyrin IX used for photodiagnosis and hypericum extract, a herbal antidepressant.

Journal: The British journal of dermatology 20010401

Title: Girard's reagent P derivative of beta-Apo-8'-carotenal: a potent photoprotective agent.

Journal: Photochemistry and photobiology 20010401

Title: Routine experimental system for defining conditions used in photodynamic therapy and fluorescence photodetection of (non-) neoplastic epithelia.

Journal: Journal of biomedical optics 20010401

Title: Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.

Journal: Journal of photochemistry and photobiology. B, Biology 20010401

Title: Modulator of heme biosynthesis induces apoptosis in leukemia cells.

Journal: Journal of clinical laser medicine & surgery 20010401

Title: Mechanisms involved in the blunted nitric oxide-cGMP pathway in hypertensive TGR(mREN2)27 rats.

Journal: European journal of pharmacology 20010309

Title: New Heck-type reaction applied to the synthesis of protoporphyrin-IX derivatives.

Journal: Organic letters 20010222

Title: Endogenous production of protoporphyrin IX induced by 5-aminolevulinic acid in leukemia cells.

Journal: Acta pharmacologica Sinica 20010201

Title: A plastidic ABC protein involved in intercompartmental communication of light signaling.

Journal: Genes & development 20010101

Title: Porphyrin bleaching and PDT-induced spectral changes are irradiance dependent in ALA-sensitized normal rat skin in vivo.

Journal: Photochemistry and photobiology 20010101

Title: Light irradiation increases embryotoxicity of photodynamic therapy sensitizers (5-aminolevulinic acid and protoporphyrin IX) in chick embryos.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101

Title: Tissue distribution and penetration of 5-ALA induced fluorescence in an amelanotic melanoma after topical application.

Journal: Anticancer research 20010101

Title: Studies on the effect of photodynamic therapy on in vitro cultured neoplastic cells.

Journal: Folia histochemica et cytobiologica 20010101

Title: An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part I. Design, spectral and spatial characteristics.

Journal: Lasers in medical science 20010101

Title: An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part II. In vivo testing.

Journal: Lasers in medical science 20010101

Title: Fractionated illumination for oesophageal ALA-PDT: effect on blood flow and PpIX formation.

Journal: Lasers in medical science 20010101

Title: Can autofluorescence demarcate basal cell carcinoma from normal skin? A comparison with protoporphyrin IX fluorescence.

Journal: Acta dermato-venereologica 20010101

Title: A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with delta-aminolaevulinic acid.

Journal: European journal of pharmacology 20001013

Title: Topological alteration of the CYP3A4 active site by the divalent cation Mg(2+).

Journal: Drug metabolism and disposition: the biological fate of chemicals 20001001

Title: The morphological changes in rat bladder after photodynamic therapy with 5-aminolaevulinic acid-induced protoporphyrin IX.

Journal: BJU international 20000701

Title: The heme synthesis and degradation pathways: role in oxidant sensitivity. Heme oxygenase has both pro- and antioxidant properties.

Journal: Free radical biology & medicine 20000115

Title: MAP kinase-independent induction of proto-oncogene c-fos mRNA by hemin in human cells.

Journal: Biochemical and biophysical research communications 19990624

Title: A screening assay for antiviral compounds targeted to the HIV-1 gp41 core structure using a conformation-specific monoclonal antibody.

Journal: Journal of virological methods 19990601

Title: Non-iron metalloporphyrins: potent antibacterial compounds that exploit haem/Hb uptake systems of pathogenic bacteria.

Journal: Molecular microbiology 19990101

Title: Influence of a haematoporphyrin derivative on the protoporphyrin IX synthesis and photodynamic effect after 5-aminolaevulinic acid sensitization in human colon carcinoma cells.

Journal: British journal of cancer 19970101

Title: Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): mechanisms and clinical results.

Journal: Journal of clinical laser medicine & surgery 19961001

Title: Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp120 envelope glycoprotein of the human immunodeficiency virus type 1.

Journal: Journal of medicinal chemistry 19940415

Title: Specific inhibition of HIV-1 protease by boronated porphyrins.

Journal: Journal of medicinal chemistry 19920904

Title: Anti-HIV activity of protoporphyrin.

Journal: AIDS (London, England) 19890601

Title: Yasushi Nakai, et al.Protoporphyrin IX induced by 5-aminolevulinic acid in bladder cancer cells in voided urine can be extracorporeally quantified using a spectrophotometer.

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SDS
Tags:553-12-8 Molecular Formula|553-12-8 MDL|553-12-8 SMILES|553-12-8 21H,23H-Porphine-2,18-dipropanoic acid,7,12-diethenyl-3,8,13,17-tetramethyl-