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55750-53-3,MFCD00043140
Catalog No.:AA00I9V9

55750-53-3 | 6-Maleimidocaproic acid

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1g
98%
in stock  
$11.00   $8.00
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5g
98%
in stock  
$21.00   $15.00
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25g
95%
in stock  
$32.00   $23.00
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100g
98%
in stock  
$112.00   $78.00
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500g
98%
in stock  
$557.00   $390.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00I9V9
Chemical Name:
6-Maleimidocaproic acid
CAS Number:
55750-53-3
Molecular Formula:
C10H13NO4
Molecular Weight:
211.2145
MDL Number:
MFCD00043140
SMILES:
OC(=O)CCCCCN1C(=O)C=CC1=O
Properties
Properties
 
Form:
Solid  
MP:
86-91 °C  
Stability:
Moisture Sensitive  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
291  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
1.1  

Literature

Title: Tailored PEG for rh-G-CSF analogue site-specific conjugation.

Journal: Bioconjugate chemistry 20090601

Title: Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).

Journal: International journal of cancer 20080301

Title: Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B.

Journal: Archiv der Pharmazie 20070801

Title: Studies on heterobifunctional cross-linking reagents, 6-maleimidohexanoic acid active esters.

Journal: Chemical & pharmaceutical bulletin 20070401

Title: Exploiting the substrate tolerance of farnesyltransferase for site-selective protein derivatization.

Journal: Chembiochem : a European journal of chemical biology 20070305

Title: Development of albumin-binding camptothecin prodrugs using a Peptide positional scanning library.

Journal: Bioconjugate chemistry 20070101

Title: Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen.

Journal: Archiv der Pharmazie 20051001

Title: Synthesis and biological activity of water-soluble maleimide derivatives of the anticancer drug carboplatin designed as albumin-binding prodrugs.

Journal: Bioconjugate chemistry 20040101

Title: Carbohydrate-centered maleimide cluster as a new type of templates for multivalent peptide assembling. synthesis of multivalent HIV-1 gp41 peptides.

Journal: Bioorganic & medicinal chemistry 20030102

Title: CNS neurons express two distinct plasma membrane electron transport systems implicated in neuronal viability.

Journal: Journal of neurochemistry 20021101

Title: Design, synthesis, and biochemical evaluation of N-substituted maleimides as inhibitors of prostaglandin endoperoxide synthases.

Journal: Journal of medicinal chemistry 19960412

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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SDS
Tags:55750-53-3 Molecular Formula|55750-53-3 MDL|55750-53-3 SMILES|55750-53-3 6-Maleimidocaproic acid