Home Carboxes 58-94-6
58-94-6,MFCD00058576
Catalog No.:AA00IA8S

58-94-6 | 6-chloro-1,1-dioxo-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$24.00   $17.00
- +
5g
98%
in stock  
$34.00   $24.00
- +
25g
95%
in stock  
$62.00   $44.00
- +
100g
95%
in stock  
$112.00   $78.00
- +
500g
95%
in stock  
$295.00   $206.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IA8S
Chemical Name:
6-chloro-1,1-dioxo-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
CAS Number:
58-94-6
Molecular Formula:
C7H6ClN3O4S2
Molecular Weight:
295.7232
MDL Number:
MFCD00058576
SMILES:
Clc1cc2N=CNS(=O)(=O)c2cc1S(=O)(=O)N
Properties
Properties
 
Form:
Solid  
MP:
342-343°C  
Refractive Index:
1.6100 (estimate)  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
532  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-0.2  

Literature

Title: Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.

Journal: Chemical research in toxicology 20150518

Title: Impact of process variables on the micromeritic and physicochemical properties of spray-dried microparticles--Part II. Physicochemical characterisation of spray-dried materials.

Journal: The Journal of pharmacy and pharmacology 20121101

Title: GPR35 is a target of the loop diuretic drugs bumetanide and furosemide.

Journal: Pharmacology 20120101

Title: Chitosan-alginate microcapsules of amoxicillin for gastric stability and mucoadhesion.

Journal: Journal of advanced pharmaceutical technology & research 20120101

Title: Diuretics for respiratory distress syndrome in preterm infants.

Journal: The Cochrane database of systematic reviews 20111207

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: About muscle insertions in man (Proposal for a new nomenclature of striated muscle).

Journal: Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 20110601

Title: Tongue necrosis as a complication of vasoconstrictor agents in the intensive care setting.

Journal: Internal and emergency medicine 20110401

Title: Tip for preventing chemosis after swinging eyelid procedure.

Journal: Orbit (Amsterdam, Netherlands) 20110301

Title: Preparation and characterisation of novel chlorothiazide potassium solid-state salt forms: Intermolecular self assembly suprastructures.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110214

Title: Adverse effect profile of trichlormethiazide: a retrospective observational study.

Journal: Cardiovascular diabetology 20110101

Title: Preparation and solid state characterisation of chlorothiazide sodium intermolecular self-assembly suprastructure.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223

Title: Transparotid approach for mandibular condylar neck and subcondylar fractures.

Journal: Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.

Journal: Bioorganic & medicinal chemistry 20101101

Title: Hypertension, antihypertensive medication use, and breast cancer risk in the California Teachers Study cohort.

Journal: Cancer causes & control : CCC 20101001

Title: Impacts of intensive agricultural irrigation and livestock farming on a semi-arid Mediterranean catchment.

Journal: Environmental monitoring and assessment 20100801

Title: Speeding up the process urine sample pre-treatment: some perspectives on the use of microwave assisted extraction in the anti-doping field.

Journal: Talanta 20100615

Title: Thiazide-induced hyponatremia.

Journal: Electrolyte & blood pressure : E & BP 20100601

Title: Surgical anatomy of the lower eyelid relating to lower blepharoplasty.

Journal: Anatomy & cell biology 20100301

Title: Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.

Journal: Bioorganic & medicinal chemistry letters 20100101

Title: Running away experience and psychoactive substance use among adolescents in Taiwan: multi-city street outreach survey.

Journal: BMC public health 20100101

Title: Formulation optimization of hydrodynamically balanced oral controlled release bioadhesive tablets of tramadol hydrochloride.

Journal: Scientia pharmaceutica 20100101

Title: Buccal fat pad versus sandwich graft for treatment of oroantral defects: A comparison.

Journal: National journal of maxillofacial surgery 20100101

Title: Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.

Journal: Bioorganic & medicinal chemistry 20091001

Title: Do new drugs increase life expectancy? A critique of a Manhattan Institute paper.

Journal: Journal of general internal medicine 20090501

Title: Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis.

Journal: Journal of chromatography. A 20090320

Title: Preparation and characterization of novel semi-interpenetrating polymer network hydrogel microspheres of chitosan and hydroxypropyl cellulose for controlled release of chlorothiazide.

Journal: Journal of microencapsulation 20090201

Title: Expression of therapeutic misconception amongst Egyptians: a qualitative pilot study.

Journal: BMC medical ethics 20090101

Title: Healing virtue: Saludadores versus witches in early modern Spain.

Journal: Medical history. Supplement 20090101

Title: Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal: Journal of medicinal chemistry 20081113

Title: A simple and rapid high-performance liquid chromatographic method for the determination of bisoprolol fumarate and hydrochlorothiazide in a tablet dosage form.

Journal: Journal of pharmaceutical and biomedical analysis 20081104

Title: Diuretics for respiratory distress syndrome in preterm infants.

Journal: The Cochrane database of systematic reviews 20080123

Title: Solving molecular crystal structures from X-ray powder diffraction data: the challenges posed by gamma-carbamazepine and chlorothiazide N,N,-dimethylformamide (1/2) solvate.

Journal: Journal of pharmaceutical sciences 20070501

Title: Fast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening protocol for antidoping analysis.

Journal: Journal of chromatography. A 20061201

Title: Prolonged hyperinsulinaemic hypoglycaemia in newborns with intrauterine growth retardation.

Journal: Archives of disease in childhood. Fetal and neonatal edition 20061101

Title: The diagnosis of ectopic focal hyperinsulinism of infancy with [18F]-dopa positron emission tomography.

Journal: The Journal of clinical endocrinology and metabolism 20060801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Hyperinsulinism of infancy associated with a novel splice site mutation in the SCHAD gene.

Journal: The Journal of pediatrics 20050501

Title: Thiazide diuretics and the risk of gallbladder disease requiring surgery in women.

Journal: Archives of internal medicine 20050314

Title: Hyperinsulinism in tyrosinaemia type I.

Journal: Journal of inherited metabolic disease 20050101

Title: Releasing the flood waters: diuril and the reshaping of hypertension.

Journal: Bulletin of the history of medicine 20050101

Title: Drug-induced pulmonary edema and acute respiratory distress syndrome.

Journal: Clinics in chest medicine 20040301

Title: Severe transient neonatal hyperinsulinism associated with hyperlactataemia in non-asphyxiated infants.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20040201

Title: Hyperinsulinaemic hypoglycaemia in preterm neonates.

Journal: Archives of disease in childhood. Fetal and neonatal edition 20040101

Title: Glutamate receptor subtypes in human retinal horizontal cells.

Journal: Visual neuroscience 20040101

Title: Detubulation abolishes membrane potential stabilization in amphibian skeletal muscle.

Journal: Journal of muscle research and cell motility 20040101

Title: Electrochemical behavior of the antituberculosis drug isoniazid and its square-wave adsorptive stripping voltammetric estimation in bulk form, tablets and biological fluids at a mercury electrode.

Journal: Journal of pharmaceutical and biomedical analysis 20031124

Title: Pamidronate in a girl with chronic renal insufficiency dependent on parenteral nutrition.

Journal: Pediatric nephrology (Berlin, Germany) 20030701

Title: Fluvastatin-induced rhabdomyolysis.

Journal: The Annals of pharmacotherapy 20021201

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Hyponatraemia and hypokalaemia due to indapamide.

Journal: The Medical journal of Australia 20020304

Title: Unexplained systemic hypertension after closure of ductus arteriosus.

Journal: Asian cardiovascular & thoracic annals 20020301

Title: Are certain diuretics also anticonvulsants?

Journal: Annals of neurology 20011001

Title: Physicochemical properties of liposomes incorporating hydrochlorothiazide and chlorothiazide.

Journal: Journal of drug targeting 20010101

Title: Effect of thiazide on established furosemide-induced nephrocalcinosis in the young rat.

Journal: Pediatric nephrology (Berlin, Germany) 20000101

Title: Thiazide therapy for ACTH-induced hypercalciuria and nephrolithiasis.

Journal: Acta paediatrica (Oslo, Norway : 1992) 19920301

Title: Milk-alkali syndrome associated with use of chlorothiazide and calcium carbonate.

Journal: Clinical pharmacy 19890301

Title: Clopamide: plasma concentrations and diuretic effect in humans.

Journal: Clinical pharmacology and therapeutics 19870901

Title: Diuretic-associated pancreatitis: a collective review and illustrative cases.

Journal: The American journal of gastroenterology 19870901

Title: Severe hypertension and lithium intoxication.

Journal: JAMA 19840406

Title: Thiazide-induced hyponatremia.

Journal: Southern medical journal 19831101

Title: Reversal of vitamin-D2-induced hypercalciuria by chlorothiazide.

Journal: Pediatric research 19830201

Title: Renal calcifications: a complication of long-term furosemide therapy in preterm infants.

Journal: Pediatrics 19820901

Title: Potassium loss associated with hydrochlorothiazide versus chlorthalidone.

Journal: Clinical therapeutics 19810101

Title: Study of factors which modify the development of norepinephrine-induced acute renal failure in the dog.

Journal: Kidney international 19790301

Title: Cimetidine and visual hallucinations.

Journal: JAMA 19780721

Title: Hyperosmolality complicating recovery from lithium toxicity.

Journal: British medical journal 19780610

Title: Adjustment of lithium dose during lithium-chlorothiazide therapy.

Journal: Clinical pharmacology and therapeutics 19770801

Title: On the mechanism of lithium-induced diabetes insipidus in man and the rat.

Journal: The Journal of clinical investigation 19740401

Title: Lithium-induced diabetes insipidus: manic symptoms, brain and electrolyte correlates, and chlorothiazide treatment.

Journal: The American journal of psychiatry 19730901

Title: Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism.

Journal: Annals of internal medicine 19721001

Title: Chlorothiazide-induced hypercalcemia in juvenile osteoporosis and hyperparathyroidism.

Journal: The New England journal of medicine 19690710

Title: Iliacus haematoma syndrome as a complication of anticoagulant therapy.

Journal: British medical journal 19681012

Title: Toxic effects of a chlorothiazide-diazoxide combination on adipose tissue and kidneys of intact rats.

Journal: Diabetologia 19680601

Title: Metabolic and hormonal studies in a patient with primary aldosteronism, presenting with acute hypokalaemic paresis induced by chlorothiazide.

Journal: Australasian annals of medicine 19680501

Title: Pogacar PR, et al. Management of central diabetes insipidus in infancy with low renal solute load formula and chlorothiazide. Curr Opin Pediatr. 2000 Aug;12(4):405-11.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 58-94-6
Tags:58-94-6 Molecular Formula|58-94-6 MDL|58-94-6 SMILES|58-94-6 6-chloro-1,1-dioxo-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide