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Title: Pro-oxidant/pro-inflammatory alterations in the offspring´s heart of mild diabetic rats are regulated by maternal treatments with a mitochondrial antioxidant.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20171001
Title: Prevention of gentamicin-induced apoptosis with the mitochondria-targeted antioxidant mitoquinone.
Journal: The Laryngoscope 20121101
Title: Chemical and technological delivery systems for idebenone: a review of literature production.
Journal: Expert opinion on drug delivery 20121101
Title: Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation.
Journal: International journal of pharmaceutics 20120915
Title: Idebenone loaded solid lipid nanoparticles interact with biomembrane models: calorimetric evidence.
Journal: Molecular pharmaceutics 20120904
Title: Analysis of the structural and mechanistic factors in antioxidants that preserve mitochondrial function and confer cytoprotection.
Journal: Bioorganic & medicinal chemistry 20120901
Title: Antioxidants and other pharmacological treatments for Friedreich ataxia.
Journal: The Cochrane database of systematic reviews 20120418
Title: Monogenic mitochondrial disorders.
Journal: The New England journal of medicine 20120322
Title: Nanostructured lipid carriers improve skin permeation and chemical stability of idebenone.
Journal: AAPS PharmSciTech 20120301
Title: Is Leber hereditary optic neuropathy treatable? Encouraging results with idebenone in both prospective and retrospective trials and an illustrative case.
Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20120301
Title: Erythropoietin in Friedreich ataxia: no effect on frataxin in a randomized controlled trial.
Journal: Movement disorders : official journal of the Movement Disorder Society 20120301
Title: Assessment of neurological efficacy of idebenone in pediatric patients with Friedreich's ataxia: data from a 6-month controlled study followed by a 12-month open-label extension study.
Journal: Journal of neurology 20120201
Title: The effects of idebenone on mitochondrial bioenergetics.
Journal: Biochimica et biophysica acta 20120201
Title: Towards a modern definition of vitamin E-evidence for a quinone hypothesis.
Journal: Bioorganic & medicinal chemistry letters 20120101
Title: Idebenone-induced recovery of glycerol-3-phosphate and succinate oxidation inhibited by digitonin.
Journal: Physiological research 20120101
Title: In vitro evaluation on a model of blood brain barrier of idebenone-loaded solid lipid nanoparticles.
Journal: Journal of nanoscience and nanotechnology 20120101
Title: Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I.
Journal: PloS one 20120101
Title: Determination of idebenone in plasma by HPLC with post-column fluorescence derivatization using 2-cyanoacetamide.
Journal: Chemical & pharmaceutical bulletin 20120101
Title: Idebenone protects against retinal damage and loss of vision in a mouse model of Leber's hereditary optic neuropathy.
Journal: PloS one 20120101
Title: Effect of long-term oral treatment with L-arginine and idebenone on the prevention of stroke-like episodes in an adult MELAS patient.
Journal: Revue neurologique 20111101
Title: Idebenone induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells.
Journal: Neurotoxicity research 20111101
Title: A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy.
Journal: Brain : a journal of neurology 20110901
Title: Idebenone treatment in Leber's hereditary optic neuropathy.
Journal: Brain : a journal of neurology 20110901
Title: Treatment of Leber hereditary optic neuropathy.
Journal: Brain : a journal of neurology 20110901
Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal: Journal of medicinal chemistry 20110714
Title: Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110701
Title: α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging.
Journal: Bioorganic & medicinal chemistry letters 20110615
Title: In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain.
Journal: Drug development and industrial pharmacy 20110601
Title: Idebenone as a novel, therapeutic approach for Duchenne muscular dystrophy: results from a 12 month, double-blind, randomized placebo-controlled trial.
Journal: Neuromuscular disorders : NMD 20110601
Title: Effects of liposomal encapsulation on the antioxidant activity of lipophilic prodrugs of idebenone.
Journal: Journal of liposome research 20110301
Title: Combined therapy with idebenone and deferiprone in patients with Friedreich's ataxia.
Journal: Cerebellum (London, England) 20110301
Title: Idebenone in Friedreich ataxia cardiomyopathy-results from a 6-month phase III study (IONIA).
Journal: American heart journal 20110301
Title: NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels.
Journal: PloS one 20110101
Title: [Idebenone (noben) -- from theory to practice].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101
Title: Differential expression of PGC-1α and metabolic sensors suggest age-dependent induction of mitochondrial biogenesis in Friedreich ataxia fibroblasts.
Journal: PloS one 20110101
Title: Updates in neuro-ophthalmology. Highlights from the 37th annual meeting of the North American Neuro-Ophthalmology Society,February 5-10, 2011, Vancouver, Canada.
Journal: Reviews in neurological diseases 20110101
Title: Antioxidant therapy: current status and future prospects.
Journal: Current medicinal chemistry 20110101
Title: Idebenone and resveratrol extend lifespan and improve motor function of HtrA2 knockout mice.
Journal: PloS one 20110101
Title: Antioxidant idebenone-loaded nanoparticles based on chitosan and N-carboxymethylchitosan.
Journal: Nanomedicine : nanotechnology, biology, and medicine 20101201
Title: Pharmacokinetic evaluation of idebenone.
Journal: Expert opinion on drug metabolism & toxicology 20101101
Title: Synthesis and characterization of mitoQ and idebenone analogues as mediators of oxygen consumption in mitochondria.
Journal: Bioorganic & medicinal chemistry 20100901
Title: Nitric oxide pros and cons: The role of L-arginine, a nitric oxide precursor, and idebenone, a coenzyme-Q analogue in ameliorating cerebral hypoxia in rat.
Journal: Brain research bulletin 20100830
Title: A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia.
Journal: Archives of neurology 20100801
Title: Exercise capacity and idebenone intervention in children and adolescents with Friedreich ataxia.
Journal: Archives of physical medicine and rehabilitation 20100701
Title: Intermediate-dose idebenone and quality of life in Friedreich ataxia.
Journal: Pediatric neurology 20100501
Title: Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade.
Journal: Molecular genetics and metabolism 20100301
Title: Coenzyme Q10 in neuromuscular and neurodegenerative disorders.
Journal: Current drug targets 20100101
Title: Emergent and unusual allergens in cosmetics.
Journal: Dermatitis : contact, atopic, occupational, drug 20100101
Title: Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects.
Journal: PloS one 20100101
Title: [The use of noben (idebenone) in the complex treatment of episodic and chronic migraine].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Title: Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20091201
Title: Antioxidants and other pharmacological treatments for Friedreich ataxia.
Journal: The Cochrane database of systematic reviews 20091007
Title: Neurophysiological evaluation in children with Friedreich's ataxia.
Journal: Early human development 20091001
Title: Low-dose idebenone treatment in Friedreich's ataxia with and without cardiac hypertrophy.
Journal: Journal of neurology 20090901
Title: Characterizing gait, locomotor status, and disease severity in children and adolescents with Friedreich ataxia.
Journal: Journal of neurologic physical therapy : JNPT 20090901
Title: Use of Noben (idebenone) in the treatment of dementia and memory impairments without dementia.
Journal: Neuroscience and behavioral physiology 20090601
Title: Pharmacokinetics and metabolism of idebenone in healthy male subjects.
Journal: European journal of clinical pharmacology 20090501
Title: Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: a long-term follow-up study.
Journal: Journal of the neurological sciences 20090315
Title: Investigating idebenone and idebenone linoleate metabolism: in vitro pig ear and mouse melanocyte studies.
Journal: Journal of cosmetic dermatology 20090301
Title: Introduction. Idebenone in the treatment of Friedreich ataxia.
Journal: Journal of neurology 20090301
Title: Idebenone: an emerging therapy for Friedreich ataxia.
Journal: Journal of neurology 20090301
Title: Pharmacokinetic properties and metabolism of idebenone.
Journal: Journal of neurology 20090301
Title: Clinical experience with high-dose idebenone in Friedreich ataxia.
Journal: Journal of neurology 20090301
Title: Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance.
Journal: European heart journal 20090101
Title: Pharmacotherapy for Friedreich ataxia.
Journal: CNS drugs 20090101
Title: Idebenone treatment in paediatric and adult patients with Friedreich ataxia: long-term follow-up.
Journal: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20081101
Title: Idebenone in Friedreich's ataxia.
Journal: Expert opinion on pharmacotherapy 20080901
Title: Allergic contact dermatitis to hydroxydecyl ubiquinone (idebenone) following application of anti-ageing cosmetic cream.
Journal: Contact dermatitis 20080901
Title: An update on inherited ataxias.
Journal: Current neurology and neuroscience reports 20080701
Title: Activity of 1,4-benzoquinones against formosan subterranean termites (Coptotermes formosanus).
Journal: Journal of agricultural and food chemistry 20080611
Title: Determination of the antioxidative capacity of an antioxidant complex and idebenone: an in vitro rapid and sensitive method.
Journal: Journal of cosmetic dermatology 20080601
Title: Antioxidant use in Friedreich ataxia.
Journal: Journal of the neurological sciences 20080415
Title: Allergic contact dermatitis to idebenone in an over-the-counter anti-ageing cream.
Journal: Contact dermatitis 20080401
Title: Allergic contact dermatitis to hydroxydecyl ubiquinone: a newly described contact allergen in cosmetics.
Journal: Contact dermatitis 20080401
Title: Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone).
Journal: Journal of bioenergetics and biomembranes 20080401
Title: Effect of the antioxidant idebenone on adverse events under mycophenolate mofetil therapy in a rat model.
Journal: Transplantation 20080315
Title: Synthesis and evaluation of 2'-hydroxyethyl trans-apovincaminate derivatives as antioxidant and cognitive enhancer agents.
Journal: Journal of medicinal chemistry 20080214
Title: Antioxidant protection against acoustic trauma by coadministration of idebenone and vitamin E.
Journal: Neuroreport 20080212
Title: Cosmeceuticals for the attenuation of extrinsic and intrinsic dermal aging.
Journal: Journal of drugs in dermatology : JDD 20080201
Title: Biochemical study of idebenone effect on mitochondrial metabolism of yeast.
Journal: Cell biology international 20080101
Title: [Noben (idebenone) in the treatment of dementia and memory impairment without dementia].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
Title: Effect of CoQ homologues on reactive oxygen generation by mitochondria.
Journal: BioFactors (Oxford, England) 20080101
Title: Neurological effects of high-dose idebenone in patients with Friedreich's ataxia: a randomised, placebo-controlled trial.
Journal: The Lancet. Neurology 20071001
Title: A comparison of the relative antioxidant potency of L-ergothioneine and idebenone.
Journal: Journal of cosmetic dermatology 20070901
Title: Protective effects of Fe-Aox29, a novel antioxidant derived from a molecular combination of Idebenone and vitamin E, in immortalized fibroblasts and fibroblasts from patients with Friedreich Ataxia.
Journal: Molecular and cellular biochemistry 20070801
Title: Friedreich's ataxia: coenzyme Q10 and vitamin E therapy.
Journal: Mitochondrion 20070601
Title: Safety, tolerability, and pharmacokinetics of high-dose idebenone in patients with Friedreich ataxia.
Journal: Archives of neurology 20070601
Title: [Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy].
Journal: Archivos de la Sociedad Espanola de Oftalmologia 20070601
Title: Neurological, cardiological, and oculomotor progression in 104 patients with Friedreich ataxia during long-term follow-up.
Journal: Archives of neurology 20070401
Title: Allergic contact dermatitis to idebenone used as an antioxidant in an anti-wrinkle cream.
Journal: Contact dermatitis 20070201
Title: Idebenone, green tea, and Coffeeberry extract: new and innovative antioxidants.
Journal: Dermatologic therapy 20070101
Title: [The use of noben for correction of mitochondrial disorders in Friedrich's disease].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101
Title: A calorimetric evaluation of the interaction of amphiphilic prodrugs of idebenone with a biomembrane model.
Journal: Journal of colloid and interface science 20060715
Title: Protective properties of idebenone in noise-induced hearing loss in the guinea pig.
Journal: Neuroreport 20060626
Title: Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content.
Journal: Drug development and industrial pharmacy 20060601
Title: Ubiquinone, idebenone, and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid.
Journal: The Journal of investigative dermatology 20060501
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone.
Journal: Biochemical and biophysical research communications 20060106
Title: [The use of idebenone (noben) in neurological practice].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101
Title: Progression despite replacement of a myopathic form of coenzyme Q10 defect.
Journal: Neurology 20040824
Title: Tolerability and improved protective action of idebenone-loaded pegylated liposomes on ethanol-induced injury in primary cortical astrocytes.
Journal: Journal of pharmaceutical sciences 20040701
Title: Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia.
Journal: Human molecular genetics 20040515
Title: Quinone analogues regulate mitochondrial substrate competitive oxidation.
Journal: Biochemical and biophysical research communications 20040416
Title: Cerebrospinal fluid concentrations of idebenone in Friedreich ataxia patients.
Journal: Neuropediatrics 20040401
Title: Chemical and enzymatic stability evaluation of lipoamino acid esters of idebenone.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040301
Title: Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial.
Journal: Neurology 20040210
Title: Idebenone treatment fails to slow cognitive decline in Alzheimer's disease.
Journal: Neurology 20031209
Title: Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.
Journal: Free radical biology & medicine 20031201
Title: Mitochondria-targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20031001
Title: [Successful idebenone therapy of hypertrophic cardiomyopathy in Friedreich ataxia].
Journal: Orvosi hetilap 20030622
Title: Idebenone for treatment of Friedreich's ataxia?
Journal: Neurology 20030527
Title: Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial.
Journal: Neurology 20030527
Title: Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring.
Journal: Neurology 20030527
Title: A cellular model for Friedreich Ataxia reveals small-molecule glutathione peroxidase mimetics as novel treatment strategy.
Journal: Human molecular genetics 20021115
Title: Ethanol-induced injury in rat primary cortical astrocytes involves oxidative stress: effect of idebenone.
Journal: Neuroscience letters 20020823
Title: Friedreich's ataxia: idebenone treatment in early stage patients.
Journal: Neuropediatrics 20020801
Title: Molecular insights into Friedreich's ataxia and antioxidant-based therapies.
Journal: Trends in molecular medicine 20020501
Title: Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia.
Journal: Heart (British Cardiac Society) 20020401
Title: Heart hypertrophy and function are improved by idebenone in Friedreich's ataxia.
Journal: Free radical research 20020401
Title: Monitoring of idebenone treatment in patients with Friedreich's ataxia by high-pressure liquid chromatography with electrochemical detection.
Journal: Journal of neuroscience methods 20020330
Title: Safety and efficacy of idebenone versus tacrine in patients with Alzheimer's disease: results of a randomized, double-blind, parallel-group multicenter study.
Journal: Pharmacopsychiatry 20020101
Title: Improved antioxidant effect of idebenone-loaded polyethyl-2-cyanoacrylate nanocapsules tested on human fibroblasts.
Journal: Pharmaceutical research 20020101
Title: Coenzyme Q(10) and idebenone in the therapy of respiratory chain diseases: rationale and comparative benefits.
Journal: Molecular genetics and metabolism 20020101
Title: Leber's hereditary optic neuropathy (LHON/11778) with myoclonus: report of two cases.
Journal: Journal of neurology, neurosurgery, and psychiatry 20011201
Title: [Delayed apoptosis and its regulation in astrocytes].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010901
Title: Idebenone in patients with Friedreich ataxia.
Journal: Neuroscience letters 20010629
Title: Idebenone - monograph.
Journal: Alternative medicine review : a journal of clinical therapeutic 20010201
Title: Dramatic improvement in mitochondrial cardiomyopathy following treatment with idebenone.
Journal: Journal of inherited metabolic disease 20010201
Title: Vitamin E prevents apoptosis in cortical neurons during hypoxia and oxygen reperfusion.
Journal: Laboratory investigation; a journal of technical methods and pathology 19981101
Title: Idebenone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in age-related cognitive disorders.
Journal: Drugs & aging 19940801
