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60-81-1,MFCD00006591
Catalog No.:AA00IAKC

60-81-1 | Phlorizin hydrate

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Purity
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Quantity
  
1g
98%
in stock  
$21.00   $15.00
- +
5g
98%
in stock  
$25.00   $18.00
- +
10g
98%
in stock  
$48.00   $34.00
- +
25g
98%
in stock  
$62.00   $43.00
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100g
98%
in stock  
$180.00   $126.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IAKC
Chemical Name:
Phlorizin hydrate
CAS Number:
60-81-1
Molecular Formula:
C21H24O10
Molecular Weight:
436.4093
MDL Number:
MFCD00006591
SMILES:
OC[C@H]1O[C@@H](Oc2cc(O)cc(c2C(=O)CCc2ccc(cc2)O)O)[C@@H]([C@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
581  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
7  
Rotatable Bond Count:
7  
XLogP3:
1.2  

Upstream Synthesis Route

[1]OrganicLetters,2014,vol.16,#18,p.4874-4877

[1]ChemischeBerichte,1942,vol.75,p.1040,1041

[2]ChemischeBerichte,1943,vol.76,p.386,388,

[1]ChemischeBerichte,1943,vol.76,p.386,388,

[1]ChemischeBerichte,1942,vol.75,p.1040,1041

[1]GreenChemistry,2014,vol.16,#9,p.4417-4425

Downstream Synthesis Route

[1]ChemischeBerichte,1942,vol.75,p.1040,1041

[2]ChemischeBerichte,1943,vol.76,p.386,388

[1]ChemischeBerichte,1943,vol.76,p.386,388

822-39-9    60-81-1   
1-{2,4-Bis-(1,3,2dioxaphospholan-2-yloxy)-6-(2S,3R,4S,5R,6R)-3,4,5-tris-(1,3,2dioxaphospholan-2-yloxy)-6-(1,3,2dioxaphospholan-2-yloxymethyl)-tetrahydro-pyran-2-yloxy-phenyl}-3-4-(1,3,2dioxaphospholan-2-yloxy)-phenyl-propan-1-one 

[1]CarbohydrateResearch,1991,vol.220,p.49-61

[1]CarbohydrateResearch,1983,vol.118,p.205-214

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Journal: Diabetes 20100501

Title: Antimicrobial activity of phenolics and glucosinolate hydrolysis products and their synergy with streptomycin against pathogenic bacteria.

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Title: (1S)-1,5-anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-D-glucitol (TS-071) is a potent, selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for type 2 diabetes treatment.

Journal: Journal of medicinal chemistry 20100422

Title: Reduced activity and expression of mitochondrial citrate carrier in streptozotocin-induced diabetic rats.

Journal: Endocrinology 20100401

Title: Alstiphyllanines E-H, picraline and ajmaline-type alkaloids from Alstonia macrophylla inhibiting sodium glucose cotransporter.

Journal: Bioorganic & medicinal chemistry 20100315

Title: Structural hierarchy of regulatory elements in the folding and transport of an intestinal multidomain protein.

Journal: The Journal of biological chemistry 20100205

Title: Comparison of the transcellular transport of FDG and D-glucose by the kidney epithelial cell line, LLC-PK1.

Journal: Nuclear medicine communications 20100201

Title: Inhibition of oxidation of aqueous emulsions of omega-3 fatty acids and fish oil by phloretin and phloridzin.

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Title: Effect of phlorizin on SGLT2 expression in the kidney of diabetic rats.

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Journal: International journal of molecular sciences 20100101

Title: Decrease of Klotho in the kidney of streptozotocin-induced diabetic rats.

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Journal: BMC research notes 20100101

Title: Isoflavones and PPAR Signaling: A Critical Target in Cardiovascular, Metastatic, and Metabolic Disease.

Journal: PPAR research 20100101

Title: Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice.

Journal: American journal of physiology. Endocrinology and metabolism 20091201

Title: Dapagliflozin, an oral sodium glucose cotransporter type 2 inhibitor for the treatment of type 2 diabetes mellitus.

Journal: IDrugs : the investigational drugs journal 20091201

Title: Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20091201

Title: Methylation of dietary flavones increases their metabolic stability and chemopreventive effects.

Journal: International journal of molecular sciences 20091101

Title: Impact of Roux-en-Y gastric bypass surgery on rat intestinal glucose transport.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20091101

Title: Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.

Journal: Journal of medicinal chemistry 20091022

Title: Intestinal microbiota differentially affect brush border enzyme activity and gene expression in the neonatal gnotobiotic pig.

Journal: Journal of animal physiology and animal nutrition 20091001

Title: SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states.

Journal: Cardiovascular research 20091001

Title: Phloridzin-induced melanogenesis is mediated by the cAMP signaling pathway.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20091001

Title: Glucose control, the kidney, and potential treatments for diabetes: more to the story.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090901

Title: Hypoglycemia: from the laboratory to the clinic.

Journal: Diabetes care 20090801

Title: Construction of bioartificial renal tubule assist device in vitro and its function of transporting sodium and glucose.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801

Title: Expression of a Dianthus flavonoid glucosyltransferase in Saccharomyces cerevisiae for whole-cell biocatalysis.

Journal: Journal of biotechnology 20090715

Title: Seasonal variation in glucose and neutral amino acid uptake in the estuarine crab Neohelice granulata.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20090701

Title: Dietary phloridzin reduces blood glucose levels and reverses Sglt1 expression in the small intestine in streptozotocin-induced diabetic mice.

Journal: Journal of agricultural and food chemistry 20090610

Title: Impaired trafficking and subcellular localization of a mutant lactase associated with congenital lactase deficiency.

Journal: Gastroenterology 20090601

Title: Insulin stimulates Akt translocation to mitochondria: implications on dysregulation of mitochondrial oxidative phosphorylation in diabetic myocardium.

Journal: Journal of molecular and cellular cardiology 20090601

Title: Development of the renal glucose reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2.

Journal: Journal of medicinal chemistry 20090409

Title: Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes.

Journal: Diabetes care 20090401

Title: Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus.

Journal: Diabetes 20090401

Title: Active absorption of ginsenoside Rg1 in vitro and in vivo: the role of sodium-dependent glucose co-transporter 1.

Journal: The Journal of pharmacy and pharmacology 20090301

Title: A functional role for sodium-dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Synthesis and biological evaluation of phloridzin analogs as human concentrative nucleoside transporter 3 (hCNT3) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090201

Title: Effects on conformational states of the rabbit sodium/glucose cotransporter through modulation of polarity and charge at glutamine 457.

Journal: Biophysical journal 20090121

Title: Stabilization of enzyme-susceptible glucoside bonds of phloridzin through conjugation with poly(gamma-glutamic acid).

Journal: Journal of controlled release : official journal of the Controlled Release Society 20090119

Title: C-terminal loop 13 of Na+/glucose cotransporter 1 contains both stereospecific and non-stereospecific sugar interaction sites.

Journal: The Journal of biological chemistry 20090109

Title: Membrane transport of singlet oxygen monitored by dipole potential measurements.

Journal: Biophysical journal 20090107

Title: Potential mechanisms of muscle mitochondrial dysfunction in aging and obesity and cellular consequences.

Journal: International journal of molecular sciences 20090101

Title: Molecular mechanisms of tungstate-induced pancreatic plasticity: a transcriptomics approach.

Journal: BMC genomics 20090101

Title: Mapping of HNF4alpha target genes in intestinal epithelial cells.

Journal: BMC gastroenterology 20090101

Title: Animal models for clinical and gestational diabetes: maternal and fetal outcomes.

Journal: Diabetology & metabolic syndrome 20090101

Title: Intestinal absorption of aloin, aloe-emodin, and aloesin; A comparative study using two in vitro absorption models.

Journal: Nutrition research and practice 20090101

Title: Glucose transport in interlobular ducts isolated from rat pancreas.

Journal: The journal of medical investigation : JMI 20090101

Title: Glucose-dependent insulinotropic polypeptide (GIP) stimulates transepithelial glucose transport.

Journal: Obesity (Silver Spring, Md.) 20081101

Title: Channels for water efflux and influx involved in volume regulation of murine spermatozoa.

Journal: Reproduction (Cambridge, England) 20081001

Title: Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species.

Journal: Chemical research in toxicology 20081001

Title: Design and synthesis of fluorescent SGLT2 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20080915

Title: Role of beta-adrenoceptors in memory consolidation: beta3-adrenoceptors act on glucose uptake and beta2-adrenoceptors on glycogenolysis.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080901

Title: Sodium tungstate decreases sucrase and Na+/D-glucose cotransporter in the jejunum of diabetic rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080901

Title: Aglycone exploration of C-arylglucoside inhibitors of renal sodium-dependent glucose transporter SGLT2.

Journal: Bioorganic & medicinal chemistry letters 20080901

Title: Short communication: effect of temporary glycosuria on molasses consumption in Holstein calves.

Journal: Journal of dairy science 20080901

Title: Apical and basolateral localisation of GLUT2 transporters in human lung epithelial cells.

Journal: Pflugers Archiv : European journal of physiology 20080801

Title: Regioselective synthesis of plant (iso)flavone glycosides in Escherichia coli.

Journal: Applied microbiology and biotechnology 20080801

Title: Isolation and characterization of a novel glycosyltransferase that converts phloretin to phlorizin, a potent antioxidant in apple.

Journal: The FEBS journal 20080801

Title: Hormonal changes during salinity-induced leaf senescence in tomato (Solanum lycopersicum L.).

Journal: Journal of experimental botany 20080801

Title: Glucose and glucose transporters regulate lymphatic pump activity through activation of the mitochondrial ATP-sensitive K+ channel.

Journal: The journal of physiological sciences : JPS 20080801

Title: Role of hyperglycaemia in the pathogenesis of hypotension observed in type-1 diabetic rats.

Journal: International journal of experimental pathology 20080801

Title: Purification, crystallization and preliminary X-ray characterization of prunin-1, a major component of the almond (Prunus dulcis) allergen amandin.

Journal: Journal of agricultural and food chemistry 20080709

Title: Transmembrane IV of the high-affinity sodium-glucose cotransporter participates in sugar binding.

Journal: American journal of physiology. Cell physiology 20080701

Title: Diurnal rhythmicity in glucose uptake is mediated by temporal periodicity in the expression of the sodium-glucose cotransporter (SGLT1).

Journal: Surgery 20080601

Title: [Glucose-6-phosphatase from nuclear envelope in rat liver].

Journal: Investigacion clinica 20080601

Title: Anti-HIV-1 activities of compounds isolated from the medicinal plant Rhus chinensis.

Journal: Journal of ethnopharmacology 20080508

Title: Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor.

Journal: Pflugers Archiv : European journal of physiology 20080501

Title: Metabolic adaptations associated with irreversible glucose loss are different to those observed during under-nutrition.

Journal: Domestic animal endocrinology 20080401

Title: High glucose increases phosphocofilin via phosphorylation of LIM kinase due to Rho/Rho kinase activation in cultured pig proximal tubular epithelial cells.

Journal: Diabetes research and clinical practice 20080401

Title: The opposing effects of the flavonoids isoquercitrin and sissotrin, isolated from Pterospartum tridentatum, on oral glucose tolerance in rats.

Journal: Phytotherapy research : PTR 20080401

Title: Luminal fructose inhibits rat intestinal sodium-phosphate cotransporter gene expression and phosphate uptake.

Journal: The American journal of clinical nutrition 20080401

Title: A high-capacity membrane potential FRET-based assay for the sodium-coupled glucose co-transporter SGLT1.

Journal: Assay and drug development technologies 20080401

Title: Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.

Journal: Journal of medicinal chemistry 20080313

Title: Inhibitor binding in the human renal low- and high-affinity Na+/glucose cotransporters.

Journal: The Journal of pharmacology and experimental therapeutics 20080301

Title: Na(+) -glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1alpha expression and activity.

Journal: Endocrinology 20080201

Title: Protein-mediated Fatty Acid Uptake in the Heart.

Journal: Current cardiology reviews 20080201

Title: Polymer-phloridzin conjugates as an anti-diabetic drug that inhibits glucose absorption through the Na+/glucose cotransporter (SGLT1) in the small intestine.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20080104

Title: Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa.

Journal: BMC gastroenterology 20080101

Title: Genomic actions of 1,25-dihydroxyvitamin D3 on insulin receptor gene expression, insulin receptor number and insulin activity in the kidney, liver and adipose tissue of streptozotocin-induced diabetic rats.

Journal: BMC molecular biology 20080101

Title: Phlorizin prevents glomerular hyperfiltration but not hypertrophy in diabetic rats.

Journal: Experimental diabetes research 20080101

Title: Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse.

Journal: Gut 20080101

Title: Highly sensitive feature detection for high resolution LC/MS.

Journal: BMC bioinformatics 20080101

Title: Effects of AVE2268, a substituted glycopyranoside, on urinary glucose excretion and blood glucose in mice and rats.

Journal: Arzneimittel-Forschung 20080101

Title: Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin.

Journal: Nutrition research and practice 20080101

Title: Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

Journal: American journal of physiology. Endocrinology and metabolism 20071201

Title: SMIT2 mediates all myo-inositol uptake in apical membranes of rat small intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20071201

Title: D-Glucose-recognition and phlorizin-binding sites in human sodium/D-glucose cotransporter 1 (hSGLT1): a tryptophan scanning study.

Journal: Biochemistry 20071127

Title: Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat.

Journal: Biochemical and biophysical research communications 20071103

Title: Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity.

Journal: The Journal of biological chemistry 20070928

Title: Reduced oxygen concentration improves the developmental competence of mouse oocytes following in vitro maturation.

Journal: Molecular reproduction and development 20070701

Title: 6-Fluoro-6-deoxy-D-glucose as a tracer of glucose transport.

Journal: American journal of physiology. Endocrinology and metabolism 20070701

Title: Unexpected similarity of intestinal sugar absorption by SGLT1 and apical GLUT2 in an insect (Aphidius ervi, Hymenoptera) and mammals.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070601

Title: Na+ -D-glucose cotransporter in the kidney of Leucoraja erinacea: molecular identification and intrarenal distribution.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20070601

Title: Downregulation of GLP-1 and GIP receptor expression by hyperglycemia: possible contribution to impaired incretin effects in diabetes.

Journal: Diabetes 20070601

Title: Effects of phloretin and phloridzin on Ca2+ handling, the action potential, and ion currents in rat ventricular myocytes.

Journal: The Journal of pharmacology and experimental therapeutics 20070601

Title: Na+-glucose cotransporter (SGLT) inhibitory flavonoids from the roots of Sophora flavescens.

Journal: Bioorganic & medicinal chemistry 20070515

Title: Potential polyphenol markers of phase change in apple (Malus domestica).

Journal: Journal of plant physiology 20070501

Title: Solute-inhibitor interactions in the plasmodial surface anion channel reveal complexities in the transport process.

Journal: Molecular pharmacology 20070501

Title: Calcium absorption by Cav1.3 induces terminal web myosin II phosphorylation and apical GLUT2 insertion in rat intestine.

Journal: The Journal of physiology 20070415

Title: Ligand-mediated conformational changes and positioning of tryptophans in reconstituted human sodium/D-glucose cotransporter1 (hSGLT1) probed by tryptophan fluorescence.

Journal: Biophysical chemistry 20070401

Title: Phlorizin induces lipolysis and alters meal patterns in both early- and late-lactation dairy cows.

Journal: Journal of dairy science 20070401

Title: Preparative separation and identification of the flavonoid phlorhizin from the crude extract of Lithocarpus polystachyus Rehd.

Journal: Molecules (Basel, Switzerland) 20070320

Title: Sodium-independent low-affinity D-glucose transport by human sodium/D-glucose cotransporter 1: critical role of tryptophan 561.

Journal: Biochemistry 20070313

Title: Is active glucose transport present in bovine ciliary body epithelium?

Journal: American journal of physiology. Cell physiology 20070301

Title: Lowering effects of onion intake on oxidative stress biomarkers in streptozotocin-induced diabetic rats.

Journal: Journal of clinical biochemistry and nutrition 20070301

Title: Inhibitory effects of phloridzin dihydrate on the activity of mushroom (Agaricus bisporus) tyrosinase.

Journal: Bioorganic & medicinal chemistry 20070201

Title: Increase of peroxisome proliferator-activated receptor delta gene expression in the lungs of streptozotocin-induced diabetic rats.

Journal: Pulmonary pharmacology & therapeutics 20070101

Title: Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level.

Journal: The Journal of pharmacology and experimental therapeutics 20070101

Title: In vitro effects of deoxynivalenol on small intestinal D-glucose uptake and absorption of deoxynivalenol across the isolated jejunal epithelium of laying hens.

Journal: Poultry science 20070101

Title: Insulin but not phlorizin treatment induces a transient increase in GLUT2 gene expression in the kidney of diabetic rats.

Journal: Nephron. Physiology 20070101

Title: Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.

Journal: International journal of medical sciences 20070101

Title: Expression of pyruvate carboxylase mRNA variants in liver of dairy cattle at calving.

Journal: PloS one 20070101

Title: Cytochrome P450 1A1 expression and activity in Caco-2 cells: modulation by apple juice extract and certain apple polyphenols.

Journal: Journal of agricultural and food chemistry 20061227

Title: Molecular identification and physiological characterization of a novel monosaccharide transporter from Arabidopsis involved in vacuolar sugar transport.

Journal: The Plant cell 20061201

Title: Comparison of the effects of selected chalcones, dihydrochalcones and some cyclic flavonoids on mitochondrial outer membrane determined by fluorescence spectroscopy.

Journal: Journal of biochemical and biophysical methods 20061130

Title: Intestinal absorption of hawthorn flavonoids--in vitro, in situ and in vivo correlations.

Journal: Life sciences 20061125

Title: Transport, deglycosylation, and metabolism of trans-piceid by small intestinal epithelial cells.

Journal: European journal of nutrition 20061001

Title: Phlorizin- and 6-ketocholestanol-mediated antagonistic modulation of alamethicin activity in phospholipid planar membranes.

Journal: Langmuir : the ACS journal of surfaces and colloids 20060926

Title: Downregulation of the constitutively expressed Hsc70 in diabetic myocardium is mediated by insulin deficiency.

Journal: The Journal of endocrinology 20060801

Title: Ligands on the string: single-molecule AFM studies on the interaction of antibodies and substrates with the Na+-glucose co-transporter SGLT1 in living cells.

Journal: Journal of cell science 20060715

Title: Nephrotoxicity of uranyl acetate: effect on rat kidney brush border membrane vesicles.

Journal: Archives of toxicology 20060701

Title: Protein changes between dormant and dormancy-broken seeds of Prunus campanulata Maxim.

Journal: Proteomics 20060701

Title: The flavonol quercetin-3-glucoside inhibits cyanidin-3-glucoside absorption in vitro.

Journal: Journal of agricultural and food chemistry 20060628

Title: Chronic high glucose inhibits albumin reabsorption by lysosomal alkalinization in cultured porcine proximal tubular epithelial cells (LLC-PK1).

Journal: Diabetes research and clinical practice 20060601

Title: Decreased polyphenol transport across cultured intestinal cells by a salivary proline-rich protein.

Journal: Biochemical pharmacology 20060528

Title: Modulation of oxidative cell damage by reconstituted mixtures of phenolic apple juice extracts in human colon cell lines.

Journal: Molecular nutrition & food research 20060401

Title: Absorption of toxic beta-glucosides produced by plants and their effect on tissue trehalases from insects.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060301

Title: [The role of facilitated diffusion in glucose transport across the apical membrane of enterocytes].

Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20060301

Title: Noninvasive evaluation of intestinal lactase with 4-galactosylxylose: comparison with 3- and 2-galactosylxylose and optimization of the method in rats.

Journal: Clinical chemistry 20060201

Title: Inhibition of intestinal and renal Na+-glucose cotransporter by naringenin.

Journal: The international journal of biochemistry & cell biology 20060101

Title: Genotyping of the lactase-phlorizin hydrolase -13910 polymorphism by LightCycler PCR and implications for the diagnosis of lactose intolerance.

Journal: Clinical chemistry 20060101

Title: Inhibition of fatty acid synthase by polyphenols.

Journal: Current medicinal chemistry 20060101

Title: [Influence of phloretin and phloridzin on digestive and adsorptive characteristics of rat small intestine].

Journal: Zhurnal evoliutsionnoi biokhimii i fiziologii 20060101

Title: Fast and simultaneous detection of prominent natural antioxidants using analytical microsystems for capillary electrophoresis with a glassy carbon electrode: a new gateway to food environments.

Journal: Electrophoresis 20051201

Title: Changes in bladder nerve-growth factor and p75 genetic expression in streptozotocin-induced diabetic rats.

Journal: BJU international 20051201

Title: A 96-well automated method to study inhibitors of human sodium-dependent D-glucose transport.

Journal: Molecular and cellular biochemistry 20051201

Title: High-yield functional expression of human sodium/d-glucose cotransporter1 in Pichia pastoris and characterization of ligand-induced conformational changes as studied by tryptophan fluorescence.

Journal: Biochemistry 20051129

Title: Inhibition of uropathogenic Escherichia coli by cranberry juice: a new antiadherence assay.

Journal: Journal of agricultural and food chemistry 20051116

Title: Contrasting effects of puerarin and daidzin on glucose homeostasis in mice.

Journal: Journal of agricultural and food chemistry 20051102

Title: SGLT-1-mediated glucose uptake protects intestinal epithelial cells against LPS-induced apoptosis and barrier defects: a novel cellular rescue mechanism?

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051101

Title: Prevention of bone loss by phloridzin, an apple polyphenol, in ovariectomized rats under inflammation conditions.

Journal: Calcified tissue international 20051101

Title: Endothelial Na+-D-glucose cotransporter: no role in insulin-mediated glucose uptake.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051101

Title: Studies on absorption and hydrolysis of ethyl alpha-D-glucoside in rat intestine.

Journal: Journal of agricultural and food chemistry 20050907

Title: Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes.

Journal: Diabetes 20050901

Title: Enhanced glucose absorption in the rat small intestine following repeated doses of 5-fluorouracil.

Journal: Chemico-biological interactions 20050815

Title: A method to quantify at late imaging a release rate of 18F-FDG in tissues.

Journal: Comptes rendus biologies 20050801

Title: Renal regulation of plasma glucose in the freshwater rainbow trout.

Journal: The Journal of experimental biology 20050701

Title: Membrane topology of loop 13-14 of the Na+/glucose cotransporter (SGLT1): a SCAM and fluorescent labelling study.

Journal: Biochimica et biophysica acta 20050630

Title: Interaction of C-terminal loop 13 of sodium-glucose cotransporter SGLT1 with lipid bilayers.

Journal: Biochemistry 20050628

Title: Serotonin-type 3 receptors mediate intestinal Polycose- and glucose-induced suppression of intake.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050601

Title: In vitro effects of deoxynivalenol on electrical properties of intestinal mucosa of laying hens.

Journal: Poultry science 20050601

Title: Intestinal D-glucose and L-alanine transport in Japanese quail (Coturnix coturnix).

Journal: Poultry science 20050601

Title: Plasmodial surface anion channel-independent phloridzin resistance in Plasmodium falciparum.

Journal: The Journal of biological chemistry 20050429

Title: Involvement of hypothalamic neuropeptide Y in regulating the amphetamine-induced appetite suppression in streptozotocin diabetic rats.

Journal: Regulatory peptides 20050415

Title: Intestinal SGLT1-mediated absorption and metabolism of benzyl beta-glucoside contained in Prunus mume: carrier-mediated transport increases intestinal availability.

Journal: Biochimica et biophysica acta 20050311

Title: Prevailing hyperglycemia is critical in the regulation of glucose metabolism during exercise in poorly controlled alloxan-diabetic dogs.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20050301

Title: Dihydrochalcones from the leaves of Pieris japonica.

Journal: Journal of natural products 20050301

Title: Kinetics of the reverse mode of the Na+/glucose cotransporter.

Journal: The Journal of membrane biology 20050301

Title: Cellular uptake and efflux of trans-piceid and its aglycone trans-resveratrol on the apical membrane of human intestinal Caco-2 cells.

Journal: Journal of agricultural and food chemistry 20050209

Title: Posttranslational regulation of NO synthase activity in the renal medulla of diabetic rats.

Journal: American journal of physiology. Renal physiology 20050101

Title: Characterization of glucose uptake by cultured rat podocytes.

Journal: Kidney & blood pressure research 20050101

Title: Dynamic changes in {beta}-cell mass and pancreatic insulin during the evolution of nutrition-dependent diabetes in psammomys obesus: impact of glycemic control.

Journal: Diabetes 20050101

Title: Insulin deficiency downregulated heat shock protein 60 and IGF-1 receptor signaling in diabetic myocardium.

Journal: Diabetes 20050101

Title: Phlorizin: a review.

Journal: Diabetes/metabolism research and reviews 20050101

Title: In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer.

Journal: Nutrition journal 20050101

Title: Inositol transport in mouse embryonic stem cells.

Journal: Reproduction, fertility, and development 20050101

Title: Acute effects of glucose and insulin on vascular endothelium.

Journal: Diabetologia 20041201

Title: Micropuncture: unlocking the secrets of renal function.

Journal: American journal of physiology. Renal physiology 20041101

Title: Phloridzin improves hyperglycemia but not hepatic insulin resistance in a transgenic mouse model of type 2 diabetes.

Journal: Diabetes 20041101

Title: Apical sodium-glucose co-transport can be regulated by blood-borne glucose in the ruminal epithelium of sheep (Ovis aries, Merino breed).

Journal: The British journal of nutrition 20041101

Title: Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20041018

Title: Portal venous hyperinsulinemia does not stimulate gut glucose absorption in the conscious dog.

Journal: Metabolism: clinical and experimental 20041001

Title: Phloridzin improves absorption of genistin in isolated rat small intestine.

Journal: Clinical nutrition (Edinburgh, Scotland) 20041001

Title: Permeability of human jejunal segments to gonyautoxins measured by the Ussing chamber technique.

Journal: Toxicon : official journal of the International Society on Toxinology 20041001

Title: Na-dependent D-glucose transport by intestinal brush border membrane vesicles from gilthead sea bream (Sparus aurata).

Journal: The Journal of membrane biology 20040915

Title: Phlorizin-like effect of Fraxinus excelsior in normal and diabetic rats.

Journal: Journal of ethnopharmacology 20040901

Title: High glucose reduces albumin uptake in cultured proximal tubular cells (LLC-PK1).

Journal: Diabetes research and clinical practice 20040901

Title: C-terminus loop 13 of Na+ glucose cotransporter SGLT1 contains a binding site for alkyl glucosides.

Journal: Biochemistry 20040831

Title: Hepatic glucose autoregulation: responses to small, non-insulin-induced changes in arterial glucose.

Journal: American journal of physiology. Endocrinology and metabolism 20040801

Title: Position 170 of Rabbit Na+/glucose cotransporter (rSGLT1) lies in the Na+ pathway; modulation of polarity/charge at this site regulates charge transfer and carrier turnover.

Journal: Biophysical journal 20040701

Title: Binding of phlorizin to the C-terminal loop 13 of the Na(+)/glucose cotransporter does not depend on the [560-608] disulfide bond.

Journal: Archives of biochemistry and biophysics 20040501

Title: The regulation and importance of glucose uptake in the isolated Atlantic cod heart: rate-limiting steps and effects of hypoxia.

Journal: The Journal of experimental biology 20040501

Title: Role of hydration in the conformational transitions between unliganded and liganded forms of loop 13 of the Na+/glucose cotransporter 1.

Journal: Biochemical and biophysical research communications 20040319

Title: Metformin-stimulated mannose transport in dermal fibroblasts.

Journal: The Journal of biological chemistry 20040312

Title: Hyperglycaemia potentiates the teratogenicity of retinoic acid in diabetic pregnancy in mice.

Journal: Diabetologia 20040301

Title: Characterization of 18F-FDG uptake in human endothelial cells in vitro.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20040301

Title: Na(+)-D-glucose cotransporter in muscle capillaries increases glucose permeability.

Journal: Biochemical and biophysical research communications 20040206

Title: Root border cells take up and release glucose-C.

Journal: Annals of botany 20040201

Title: Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040101

Title: Kinetic characterization of apical D-fructose transport in chicken jejunum.

Journal: The Journal of membrane biology 20040101

Title: Apple phytochemicals and their health benefits.

Journal: Nutrition journal 20040101

Title: Sodium-dependent transport of [3H](1D)chiro-inositol by Tetrahymena.

Journal: The Journal of eukaryotic microbiology 20040101

Title: A role for Ca(v)1.3 in rat intestinal calcium absorption.

Journal: Biochemical and biophysical research communications 20031212

Title: Phlorizin recognition in a C-terminal fragment of SGLT1 studied by tryptophan scanning and affinity labeling.

Journal: The Journal of biological chemistry 20031205

Title: Synthesis of photoaffinity probes [2(')-iodo-4(')-(3(')-trifluoromethyldiazirinyl)phenoxy]-D-glucopyranoside and [(4(')-benzoyl)phenoxy]-D-glucopyranoside for the identification of sugar-binding and phlorizin-binding sites in the sodium/D-glucose cotransporter protein.

Journal: Analytical biochemistry 20031201

Title: Absorption of sugars and amino acids by the epidermis of Aphidius ervi larvae.

Journal: Journal of insect physiology 20031201

Title: Synthesis of 18F-fluoroalkyl-beta-D-glucosides and their evaluation as tracers for sodium-dependent glucose transporters.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20031201

Title: High-affinity myo-inositol transport in Candida albicans: substrate specificity and pharmacology.

Journal: Microbiology (Reading, England) 20031201

Title: Differential expression of Na+/D-glucose cotransport in isolated cells of Marsupenaeus japonicus hepatopancreas.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20031101

Title: Genomic organization and functional characterization of the human concentrative nucleoside transporter-3 isoform (hCNT3) expressed in mammalian cells.

Journal: Pflugers Archiv : European journal of physiology 20031101

Title: The beta-D-glucoside and sodium-dependent glucose transporter 1 (SGLT1)-inhibitor phloridzin is transported by both SGLT1 and multidrug resistance-associated proteins 1/2.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101

Title: Aminoglycoside antibiotics reduce glucose reabsorption in kidney through down-regulation of SGLT1.

Journal: Biochemical and biophysical research communications 20030905

Title: Prior exercise enhances passive absorption of intraduodenal glucose.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20030901

Title: Response of scab-susceptible (McIntosh) and scab-resistant (Liberty) apple tissues to treatment with yeast extract and Venturia inaequalis.

Journal: Phytochemistry 20030901

Title: Evidence for rapid 'metabolic switching' through lipoprotein lipase occupation of endothelial-binding sites.

Journal: Journal of molecular and cellular cardiology 20030901

Title: In vivo sugar diffusion in the ileal epithelium of spontaneously hypertensive rats.

Journal: Scandinavian journal of gastroenterology 20030901

Title: Functional asymmetry of the human Na+/glucose transporter (hSGLT1) in bacterial membrane vesicles.

Journal: Biochemistry 20030805

Title: Alteration of alpha(1A)-adrenoceptor gene expression in the prostate of streptozotocin-induced diabetic rats.

Journal: Pharmacology 20030701

Title: Expression of Na(+) / D-glucose cotransport in Xenopus laevis oocytes by injection of poly(A)(+) RNA isolated from lobster (Homarus americanus) hepatopancreas.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20030701

Title: Synthesis and biologic evaluation of (11)c-methyl-d-glucoside, a tracer of the sodium-dependent glucose transporters.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030701

Title: Tubular reabsorption of myo-inositol vs. that of D-glucose in rat kidney in vivo et situ.

Journal: American journal of physiology. Renal physiology 20030601

Title: The monosaccharide transporter gene, AtSTP4, and the cell-wall invertase, Atbetafruct1, are induced in Arabidopsis during infection with the fungal biotroph Erysiphe cichoracearum.

Journal: Plant physiology 20030601

Title: Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats.

Journal: Journal of endocrinological investigation 20030601

Title: Binding of phlorizin to the isolated C-terminal extramembranous loop of the Na+/glucose cotransporter assessed by intrinsic tryptophan fluorescence.

Journal: Biochemistry 20030527

Title: Detection of phloridzin in strawberries (Fragaria x ananassa Duch.) by HPLC-PDA-MS/MS and NMR spectroscopy.

Journal: Journal of agricultural and food chemistry 20030507

Title: A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line.

Journal: Diabetes 20030501

Title: Loss of nucleotide regulation of epithelial chloride transport in the jejunum of P2Y4-null mice.

Journal: Molecular pharmacology 20030401

Title: Absorption of quercetin-3-glucoside and quercetin-4'-glucoside in the rat small intestine: the role of lactase phlorizin hydrolase and the sodium-dependent glucose transporter.

Journal: Biochemical pharmacology 20030401

Title: Inositol transport in preimplantation rabbit embryos: effects of embryo stage, sodium, osmolality and metabolic inhibitors.

Journal: Reproduction (Cambridge, England) 20030401

Title: Exploring levels of hexosamine biosynthesis pathway intermediates and protein kinase C isoforms in muscle and fat tissue of Zucker Diabetic Fatty rats.

Journal: Endocrine 20030401

Title: High blood glucose and osmolality, but not high urinary glucose and osmolality, affect neuronal nitric oxide synthase expression in diabetic rat kidney.

Journal: The Journal of laboratory and clinical medicine 20030301

Title: Hydrolysis by lactase phlorizin hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030301

Title: Non-nutritive bioactive food constituents of plants: bioavailability of flavonoids.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20030301

Title: An enhancer activates the pig lactase phlorizin hydrolase promoter in intestinal cells.

Journal: Gene 20030213

Title: Inositol transport in mouse oocytes and preimplantation embryos: effects of mouse strain, embryo stage, sodium and the hexose transport inhibitor, phloridzin.

Journal: Reproduction (Cambridge, England) 20030101

Title: Increase in adenosine A1 receptor gene expression in the liver of streptozotocin-induced diabetic rats.

Journal: Diabetes/metabolism research and reviews 20030101

Title: A new sweet dihydrochalcone-glucoside from leaves of Lithocarpus pachyphyllus (Kurz) Rehd. (Fagaceae).

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101

Title: pH dependence of Na+/myo-inositol cotransporters in rat thick limb cells.

Journal: Kidney international 20021201

Title: Mechanisms by which bis(maltolato)oxovanadium(IV) normalizes phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression in streptozotocin-diabetic rats in vivo.

Journal: Endocrinology 20021201

Title: AICAR and phlorizin reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat.

Journal: American journal of physiology. Endocrinology and metabolism 20021101

Title: Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment.

Journal: Endocrinology 20021101

Title: Three-dimensional structure of the inclusion complex between phloridzin and beta-cyclodextrin.

Journal: Carbohydrate research 20021011

Title: Sodium glucose-linked transport in the ruminal epithelium of fallow deer -- comparison to sheep.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20021001

Title: Glucagon-like peptide 2 enhances maltase-glucoamylase and sucrase-isomaltase gene expression and activity in parenterally fed premature neonatal piglets.

Journal: Pediatric research 20021001

Title: Influence of food deprivation on the transport of 3-O-methyl-alpha-D-glucose across the isolated ruminal epithelium of sheep.

Journal: Journal of animal science 20021001

Title: Identification of a novel Na+/myo-inositol cotransporter.

Journal: The Journal of biological chemistry 20020920

Title: Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets.

Journal: The Journal of clinical investigation 20020915

Title: Intrahepatic bile ducts transport water in response to absorbed glucose.

Journal: American journal of physiology. Cell physiology 20020901

Title: Electrogenic ion transport in the intestine of the Australian common brushtail possum, Trichosurus vulpecula: indications of novel transport patterns in a marsupial.

Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020801

Title: Enzymatic hydrolysis of pyridoxine-5'-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolase.

Journal: The Journal of biological chemistry 20020726

Title: The antioxidant activity of phloretin: the disclosure of a new antioxidant pharmacophore in flavonoids.

Journal: Biochemical and biophysical research communications 20020705

Title: Mobility of ions, sugar, and water in the cytoplasm of Xenopus oocytes expressing Na(+)-coupled sugar transporters (SGLT1).

Journal: The Journal of physiology 20020701

Title: Glucose uptake via SGLT-1 is stimulated by beta(2)-adrenoceptors in the ruminal epithelium of sheep.

Journal: The Journal of nutrition 20020601

Title: Functional activities of the colon of the desert gerbil (Gerbillus cheesmani).

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

Title: Single molecule recognition of protein binding epitopes in brush border membranes by force microscopy.

Journal: Biophysical journal 20020501

Title: Functional expression of the Vibrio parahaemolyticus Na+/galactose (vSGLT) cotransporter in Xenopus laevis oocytes.

Journal: The Journal of membrane biology 20020501

Title: On-line HPLC-DPPH screening method for evaluation of radical scavenging phenols extracted from apples (Malus domestica L.).

Journal: Journal of agricultural and food chemistry 20020424

Title: Sorbitol transport in rat renal inner medullary interstitial cells.

Journal: Kidney international 20020401

Title: Normalization of cytoplasmic calcium response in pancreatic beta-cells of spontaneously diabetic GK rat by the treatment with T-1095, a specific inhibitor of renal Na+-glucose co-transporters.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020401

Title: Regional differences in transport, lipid composition, and fluidity of apical membranes of small intestine of chicken.

Journal: Poultry science 20020401

Title: Characterization of glucose transport by cultured rabbit kidney proximal convoluted and proximal straight tubule cells.

Journal: In vitro cellular & developmental biology. Animal 20020401

Title: Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia.

Journal: The Journal of biological chemistry 20020329

Title: Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia.

Journal: Diabetes 20020201

Title: Increase of beta-endorphin biosynthesis in the adrenal gland of streptozotocin-induced diabetic rats.

Journal: Neuroscience letters 20020125

Title: Involvement of active transport systems in the mobilization of cadmium by dithiocarbamates in vivo.

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Title: Weight-loss drugs and supplements: are there safer alternatives?

Journal: Medical hypotheses 20020101

Title: Beneficial effect of T-1095, a selective inhibitor of renal Na+-glucose cotransporters, on metabolic index and insulin secretion in spontaneously diabetic GK rats.

Journal: Clinical and experimental pharmacology & physiology 20020101

Title: Decrease in catechol-O-methyltransferase activity in the liver of streptozotocin-induced diabetic rats.

Journal: Clinical and experimental pharmacology & physiology 20020101

Title: D-glucose releases 5-hydroxytryptamine from human BON cells as a model of enterochromaffin cells.

Journal: Gastroenterology 20011201

Title: Leptin effect on galactose absorption in mice jejunum.

Journal: Journal of physiology and biochemistry 20011201

Title: Antecedent hyperglycemia, not hyperlipidemia, is associated with increased islet triacylglycerol content and decreased insulin gene mRNA level in Zucker diabetic fatty rats.

Journal: Diabetes 20011101

Title: Identification of a region critically involved in the interaction of phlorizin with the rabbit sodium-D-glucose cotransporter SGLT1.

Journal: The Journal of membrane biology 20011101

Title: Increase in intrinsic anion conductance upon inhibition of the electroneutral Cl(-)/HCO(3)(-) exchanger: effect of CO(2)/HCO(3)(-).

Journal: Bioelectrochemistry (Amsterdam, Netherlands) 20011101

Title: Confocal microscopy study of the different patterns of 2-NBDG uptake in rabbit enterocytes in the apical and basal zone.

Journal: Pflugers Archiv : European journal of physiology 20011101

Title: Characterization of D-fructose transport by rat kidney brush-border membrane vesicles: changes in hypertensive rats.

Journal: Cellular and molecular life sciences : CMLS 20011101

Title: Evidence for the involvement of Ala 166 in coupling Na(+) to sugar transport through the human Na(+)/glucose cotransporter.

Journal: Biochemistry 20011002

Title: Common mechanisms of inhibition for the Na+/glucose (hSGLT1) and Na+/Cl-/GABA (hGAT1) cotransporters.

Journal: British journal of pharmacology 20011001

Title: High glucose stimulates early response gene c-Myc expression in rat pancreatic beta cells.

Journal: The Journal of biological chemistry 20010921

Title: Mapping the urea channel through the rabbit Na(+)-glucose cotransporter SGLT1.

Journal: The Journal of physiology 20010901

Title: Aldosterone mediates the changes in hexose transport induced by low sodium intake in chicken distal intestine.

Journal: The Journal of physiology 20010815

Title: EGF and TGF stimulate proabsorption of glucose and electrolytes by Na+/glucose cotransporter in awake canine model.

Journal: Digestive diseases and sciences 20010801

Title: Increase of opioid mu-receptor gene expression in streptozotocin-induced diabetic rats.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010801

Title: Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4.

Journal: The Journal of clinical investigation 20010701

Title: Induction of ependymal, glial, and neuronal transactivation by intraventricular administration of the SGLT1 Na+-D-glucose cotransporter inhibitor phlorizin.

Journal: Neurochemical research 20010701

Title: Cloning and characterization of human liver cytosolic beta-glycosidase.

Journal: The Biochemical journal 20010615

Title: Sodium-coupled glucose transporter as a functional glucose sensor of retinal microvascular circulation.

Journal: Circulation research 20010608

Title: Facilitated glucose transporters play a crucial role throughout mouse preimplantation embryo development.

Journal: Human reproduction (Oxford, England) 20010601

Title: Diphenylamine-2-carboxylic acid (DPC), Usually an inhibitor of Cl- and non-selective cation channels, inhibits Cl-/HCO3- exchange and opens Cl- and cation conductances in rabbit gallbladder epithelium.

Journal: Pflugers Archiv : European journal of physiology 20010601

Title: Nongenomic effect of testosterone on chloride secretion in cultured rat efferent duct epithelia.

Journal: American journal of physiology. Cell physiology 20010501

Title: Stimulation of non-sodium-dependent water, electrolyte, and glucose transport in rat small intestine by gum arabic.

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Title: Lactase synthesis is pretranslationally regulated in protein-deficient pigs fed a protein-sufficient diet.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010401

Title: Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter.

Journal: Biology of reproduction 20010301

Title: Diurnal rhythmicity in intestinal SGLT-1 function, V(max), and mRNA expression topography.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20010201

Title: Two-step mechanism of phlorizin binding to the SGLT1 protein in the kidney.

Journal: The Journal of membrane biology 20010201

Title: Hyperglycemia contributes to impaired insulin response in GK rat islets.

Journal: Diabetes 20010201

Title: beta-cell adaptation to hyperglycemia.

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Title: A Na+-dependent D-mannose transporter in the apical membrane of chicken small intestine epithelial cells.

Journal: Pflugers Archiv : European journal of physiology 20010201

Title: Functional asymmetry of the sodium-D-glucose cotransporter expressed in yeast secretory vesicles.

Journal: The Journal of membrane biology 20010115

Title: Improved diabetic syndrome in C57BL/KsJ-db/db mice by oral administration of the Na(+)-glucose cotransporter inhibitor T-1095.

Journal: British journal of pharmacology 20010101

Title: Effect of growth hormone on intestinal Na+/glucose cotransporter activity.

Journal: JPEN. Journal of parenteral and enteral nutrition 20010101

Title: Inhibitors of the Cl-/HCO3- exchanger activate an apical anion conductance with similar features in the epithelial cells of rabbit gallbladder: analysis in intact epithelium.

Journal: Pflugers Archiv : European journal of physiology 20010101

Title: Inhibitors of the Cl-/HCO3- exchanger activate an anion channel with similar features in the epithelial cells of rabbit gallbladder: patch-clamp analysis.

Journal: Pflugers Archiv : European journal of physiology 20010101

Title: Increased Na(+)-dependent D-glucose transport in small intestine of retinyl palmitate treated rats.

Journal: In vivo (Athens, Greece) 20010101

Title: Nutritional effects of surgical and medical treatment for short bowel syndrome.

Journal: JPEN. Journal of parenteral and enteral nutrition 20010101

Title: Hypoxia-induced increase in intracellular calcium concentration in endothelial cells: role of the Na(+)-glucose cotransporter.

Journal: Journal of cellular biochemistry 20010101

Title: Troglitazone enhances glycolysis and improves intracellular glucose metabolism in rat mesangial cells.

Journal: Metabolism: clinical and experimental 20000301

Title: Tubular sodium handling and tubuloglomerular feedback in experimental diabetes mellitus.

Journal: The American journal of physiology 19910601

Title: Phlorizin-induced glycosuria does not prevent gentamicin nephrotoxicity in rats.

Journal: Kidney international 19890401

Title: Plasma and liver metabolites and glucose kinetics as affected by prolonged ketonemia-glucosuria and fasting in steers.

Journal: Journal of dairy science 19841001

Title: In vitro hepatic gluconeogenesis and ketogenesis as affected by prolonged ketonemia-glucosuria and fasting in steers.

Journal: Journal of dairy science 19841001

Title: Effect of dietary niacin supplementation on phlorhizin and 1,3-butanediol-induced ketonemia and hypoglycemia in steers.

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Title: Katsuda Y, et al. Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin. Exp Anim. 2015;64(2):161-9.

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Tags:60-81-1 Molecular Formula|60-81-1 MDL|60-81-1 SMILES|60-81-1 Phlorizin hydrate