Home Imidazoles 61837-65-8
61837-65-8,MFCD00142316
Catalog No.:AA00IAUK

61837-65-8 | 2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$152.00   $106.00
- +
10mg
≥98%
in stock  
$208.00   $145.00
- +
25mg
≥98%
in stock  
$480.00   $336.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IAUK
Chemical Name:
2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-
CAS Number:
61837-65-8
Molecular Formula:
C12H14N2O3
Molecular Weight:
234.2512
MDL Number:
MFCD00142316
SMILES:
CCC1(NC(=O)N(C1=O)C)c1ccc(cc1)O
Properties
Computed Properties
 
Complexity:
337  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.2  

Literature

Title: Histone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cells.

Journal: PloS one 20140101

Title: Interactions of sesquiterpenes zederone and germacrone with the human cytochrome P450 system.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130901

Title: Direct and metabolism-dependent cytochrome P450 inhibition assays for evaluating drug-drug interactions.

Journal: Journal of applied toxicology : JAT 20130201

Title: Liver disease selectively modulates cytochrome P450--mediated metabolism.

Journal: Clinical pharmacology and therapeutics 20060901

Title: Enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4'-hydroxymephenytoin in human plasma and urine by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: The influence of St John's Wort on CYP2C19 activity with respect to genotype.

Journal: Journal of clinical pharmacology 20040601

Title: Validated assays for human cytochrome P450 activities.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20040601

Title: Quantification of mephenytoin and its metabolites 4'-hydroxymephenytoin and nirvanol in human urine using a simple sample processing method.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Simultaneous enantiospecific separation and quantitation of mephenytoin and its metabolites nirvanol and 4'-hydroxymephenytoin in human plasma by liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030705

Title: Comparison of in vitro and in vivo inhibition potencies of fluvoxamine toward CYP2C19.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030501

Title: Isozyme-specific induction of low-dose aspirin on cytochrome P450 in healthy subjects.

Journal: Clinical pharmacology and therapeutics 20030301

Title: mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030301

Title: Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19.

Journal: Epilepsy research 20021201

Title: Monolithic silica rod liquid chromatography with ultraviolet or fluorescence detection for metabolite analysis of cytochrome P450 marker reactions.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125

Title: Plasma levels of TNF-alpha and IL-6 are inversely related to cytochrome P450-dependent drug metabolism in patients with congestive heart failure.

Journal: Journal of cardiac failure 20021001

Title: Tanaka M, et al. Simple and selective assay of 4-hydroxymephenytoin in human urine using solid-phase extraction and high-performance liquid chromatography with electrochemical detection and its preliminary application to phenotyping test. J Chromatogr B Biomed Appl. 1996 Feb 9;676(1):87-94.

Title: Stewart NA, et al. A UPLC-MS/MS assay of the "Pittsburgh cocktail": six CYP probe-drug/metabolites from human plasma and urine using stable isotope dilution. Analyst. 2011 Feb 7;136(3):605-12.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:61837-65-8 Molecular Formula|61837-65-8 MDL|61837-65-8 SMILES|61837-65-8 2,4-Imidazolidinedione, 5-ethyl-5-(4-hydroxyphenyl)-3-methyl-