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62613-82-5,MFCD00242951
Catalog No.:AA00IAZ2

62613-82-5 | Oxiracetam

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Purity
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100mg
97%
in stock  
$6.00   $4.00
- +
250mg
97%
in stock  
$7.00   $5.00
- +
1g
97%
in stock  
$9.00   $7.00
- +
5g
97%
in stock  
$26.00   $18.00
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25g
98%
in stock  
$103.00   $73.00
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100g
97%
in stock  
$246.00   $172.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IAZ2
Chemical Name:
Oxiracetam
CAS Number:
62613-82-5
Molecular Formula:
C6H10N2O3
Molecular Weight:
158.1552
MDL Number:
MFCD00242951
SMILES:
NC(=O)CN1CC(CC1=O)O
Properties
Computed Properties
 
Complexity:
192  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-2.2  

Downstream Synthesis Route

[1]HelveticaChimicaActa,1992,vol.75,p.892-900

[1]HelveticaChimicaActa,1992,vol.75,p.892-900

[1]Patent:CN104513189,2017,B.Locationinpatent:Paragraph0152;0156-0158

[2]HelveticaChimicaActa,1992,vol.75,p.892-900

[1]Patent:US5276164,1994,A

[2]Patent:US4173569,1979,A

[3]Patent:CN105439936,2016,A.Locationinpatent:Paragraph0081;0082;0083;0095;0096

[1]Patent:WO2014/87367,2014,A2.Locationinpatent:Paragraph0099

Literature

Title: Determination of piracetam in rat plasma by LC-MS/MS and its application to pharmacokinetics.

Journal: Biomedical chromatography : BMC 20101001

Title: Efficacy study of Prunus amygdalus (almond) nuts in scopolamine-induced amnesia in rats.

Journal: Indian journal of pharmacology 20100601

Title: Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.

Journal: Drugs 20100212

Title: [Optimization of preparation of poly ( glycidyl methacrylate-divinylbenzene) monolithic column with orthogonal experiments for separation of small molecules].

Journal: Se pu = Chinese journal of chromatography 20100201

Title: [Evaluation of antihypoxic and antiamnemonic effects of mexicor in animals].

Journal: Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine 20090101

Title: Oxiracetam pre- but not post-treatment prevented social recognition deficits produced with trimethyltin in rats.

Journal: Behavioural brain research 20050620

Title: Mild cognitive impairment: animal models.

Journal: Dialogues in clinical neuroscience 20041201

Title: Rapid quantitative analysis of oxiracetam in human plasma by liquid chromatography/electrospray tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20041115

Title: Nootropic nefiracetam inhibits proconvulsant action of peripheral-type benzodiazepines in epileptic mutant EL mice.

Journal: Annals of the New York Academy of Sciences 20041001

Title: Rapid quantitative analysis of oxiracetam in human plasma by liquid chromatography/electrospray tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20040921

Title: Human models as tools in the development of psychotropic drugs.

Journal: Dialogues in clinical neuroscience 20021201

Title: Oxiracetam prevented the scopolamine but not the diazepam induced memory deficits in mice.

Journal: Behavioural brain research 20020718

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Aniracetam improves contextual fear conditioning and increases hippocampal gamma-PKC activation in DBA/2J mice.

Journal: Hippocampus 20020101

Title: The effects of ascorbic acid and oxiracetam on scopolamine-induced amnesia in a habituation test in aged mice.

Journal: Neurobiology of learning and memory 19950901

Title: Idebenone. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in age-related cognitive disorders.

Journal: Drugs & aging 19940801

Title: Synthesis and pharmacological activity of a series of dihydro-1H-pyrrolo[1,2-a]imidazole-2,5(3H,6H)-diones, a novel class of potent cognition enhancers.

Journal: Journal of medicinal chemistry 19931224

Title: Effect of oxiracetam on scopolamine-induced amnesia in the rat in a spatial learning task.

Journal: Pharmacology, biochemistry, and behavior 19921101

Title: Brain entry and direct central pharmacological effects of the nootropic drug oxiracetam. Oxiracetam: brain entry and pharmacological effects.

Journal: Pharmacopsychiatry 19891001

Title: Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine.

Journal: Pharmacology, biochemistry, and behavior 19870701

Title: Li W, et al. (S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Sci Rep. 2017 Aug 30;7(1):10052.

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