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64872-77-1,MFCD00058159
Catalog No.:AA00IBCB

64872-77-1 | Butoconazole nitrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
500mg
≥98%
in stock  
$46.00   $32.00
- +
1g
98%
in stock  
$65.00   $46.00
- +
5g
98%
in stock  
$162.00   $113.00
- +
10g
98%
in stock  
$270.00   $189.00
- +
25g
98%
in stock  
$519.00   $363.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IBCB
Chemical Name:
Butoconazole nitrate
CAS Number:
64872-77-1
Molecular Formula:
C19H18Cl3N3O3S
Molecular Weight:
474.7885
MDL Number:
MFCD00058159
SMILES:
Clc1ccc(cc1)CCC(Sc1c(Cl)cccc1Cl)Cn1cncc1.[O-][N+](=O)O
Properties
Properties
 
BP:
566.9°C at 760 mmHg  
Form:
Solid  
MP:
162-163℃  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
408  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Why are most phospholipidosis inducers also hERG blockers?

Journal: Archives of toxicology 20171201

Title: Screening of a chemical library reveals novel PXR-activating pharmacologic compounds.

Journal: Toxicology letters 20150105

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: [The statement of Polish Gynecological Society Experts on the treatment of acute vulvovaginal candidiasis with prolonged releasing 2% butoconazole nitrate vaginal cream--state of art in 2008].

Journal: Ginekologia polska 20090401

Title: In vitro evaluation of artificial ageing on surface properties and early Candida albicans adhesion to prosthetic resins.

Journal: Journal of materials science. Materials in medicine 20090101

Title: [Gynazol for treatment of vulvo-vaginal candidiasis--our experience].

Journal: Akusherstvo i ginekologiia 20070101

Title: [Treatment in cases of recurrent vaginal candida infection during pregnancy].

Journal: Akusherstvo i ginekologiia 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis.

Journal: Infectious diseases in obstetrics and gynecology 20051201

Title: Drugs for vulvovaginal candidiasis.

Journal: The Medical letter on drugs and therapeutics 20010108

Title: In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp.

Journal: Mycopathologia 19920401

Title: 1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenylthio)-n-butyl]-1H-imidazole nitrate, a new potent antifungal agent.

Journal: Journal of medicinal chemistry 19780801

Title: Anik ST, et al. Extreme vertexes design in formulation development: solubility of butoconazole nitrate in a multicomponent system. J Pharm Sci. 1981;70(8):897-900.

Title: Pharmacology refers to the chemical makeup and behavior of GYNAZOLE 1 (butoconazole nitrate cream).

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SDS
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