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6491-83-4,MFCD00155477
Catalog No.:AA00IBCH

6491-83-4 | H-Leu-leu-OMe HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$45.00   $32.00
- +
5g
97%
in stock  
$120.00   $84.00
- +
25g
97%
in stock  
$378.00   $264.00
- +
100g
97%
in stock  
$1,142.00 $799.00
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00IBCH
Chemical Name:
H-Leu-leu-OMe HCl
CAS Number:
6491-83-4
Molecular Formula:
C13H27ClN2O3
Molecular Weight:
294.8181
MDL Number:
MFCD00155477
SMILES:
COC(=O)[C@@H](NC(=O)[C@H](CC(C)C)N)CC(C)C.Cl
Properties
Computed Properties
 
Complexity:
277  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1980,vol.23,p.913-918

[1]Chemistry-AEuropeanJournal,2007,vol.13,p.10140-10151

Literature

Title: Thiele DL, et, al. The immunosuppressive activity of L-leucyl-L-leucine methyl ester: selective ablation of cytotoxic lymphocytes and monocytes. J Immunol. 1986 Feb 1;136(3):1038-48.

Title: Thiele DL, et, al. Mechanism of L-leucyl-L-leucine methyl ester-mediated killing of cytotoxic lymphocytes: dependence on a lysosomal thiol protease, dipeptidyl peptidase I, that is enriched in these cells. Proc Natl Acad Sci U S A. 1990 Jan;87(1):83-7.

Title: Kalogeropulou AF, et, al. Endogenous Rab29 does not impact basal or stimulated LRRK2 pathway activity. Biochem J. 2020 Nov 27;477(22):4397-4423.

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SDS
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Tags:6491-83-4 Molecular Formula|6491-83-4 MDL|6491-83-4 SMILES|6491-83-4 H-Leu-leu-OMe HCl
Catalog No.: AA00IBCH
6491-83-4,MFCD00155477
6491-83-4 | H-Leu-leu-OMe HCl
Pack Size： 1g
Purity： 97%
in stock
$45.00 $32.00
Pack Size： 5g
Purity： 97%
in stock
$120.00 $84.00
Pack Size： 25g
Purity： 97%
in stock
$378.00 $264.00
Pack Size： 100g
Purity： 97%
in stock
$1,142.00 $799.00
Quantity
- +
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bulk Quotation Request
Technical Information
Catalog Number: AA00IBCH
Chemical Name: H-Leu-leu-OMe HCl
CAS Number: 6491-83-4
Molecular Formula: C13H27ClN2O3
Molecular Weight: 294.8181
MDL Number: MFCD00155477
SMILES: COC(=O)[C@@H](NC(=O)[C@H](CC(C)C)N)CC(C)C.Cl
Properties
Complexity: 277  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 19  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 8  
Downstream Synthesis Route
65-86-1    6491-83-4    74019-79-7 

[1]JournalofMedicinalChemistry,1980,vol.23,p.913-918

67-56-1    3303-31-9    6491-83-4 

[1]Chemistry-AEuropeanJournal,2007,vol.13,p.10140-10151

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