Home Amines 68-41-7
68-41-7,MFCD00005353
Catalog No.:AA00IBP7

68-41-7 | (4R)-4-amino-1,2-oxazolidin-3-one

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100mg
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1g
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$8.00   $6.00
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5g
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100g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IBP7
Chemical Name:
(4R)-4-amino-1,2-oxazolidin-3-one
CAS Number:
68-41-7
Molecular Formula:
C3H6N2O2
Molecular Weight:
102.0919
MDL Number:
MFCD00005353
SMILES:
N[C@@H]1CONC1=O
NSC Number:
756712
Properties
Computed Properties
 
Complexity:
92.9  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
XLogP3:
-1.5  

Downstream Synthesis Route

[1]HelveticaChimicaActa,1957,vol.40,p.1531,1544

[1]HelveticaChimicaActa,1957,vol.40,p.1531,1544

[1]NipponKagakuZasshi,1957,vol.78,p.812    Chem.Abstr.,1960,p.4539

[1],1959,vol.8,p.1873,1884    Chem.Abstr.,1961,p.1804

[1]ChemistryofHeterocyclicCompounds,2017,vol.53,p.1248-1253    Khim.Geterotsikl.Soedin.,2017,vol.53,p.1248-1253,6

[2]JournaloftheAmericanChemicalSociety,1955,vol.77,p.2345

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Title: D-cycloserine reduces the context specificity of pavlovian extinction of cocaine cues through actions in the nucleus accumbens.

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Title: Living-donor liver transplantation in patients with concurrent active tuberculosis at transplantation.

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Title: Nervous system effects of antituberculosis therapy.

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Title: Capreomycin-induced optic neuritis in a case of multidrug resistant pulmonary tuberculosis.

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Title: Need for speed: evaluating slopes of OCD recovery in behavior therapy enhanced with d-cycloserine.

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Title: Septal and lateral wall localization of PBP5, the major D,D-carboxypeptidase of Escherichia coli, requires substrate recognition and membrane attachment.

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Title: Misindentification of Mycobacterium kumamotonense as M. tuberculosis.

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Title: The N-methyl-D-aspartate receptor co-agonist D-cycloserine facilitates declarative learning and hippocampal activity in humans.

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Title: Clostridium difficile is not associated with outbreaks of viral gastroenteritis in the elderly in the Netherlands.

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Title: Clonal expansion of multidrug-resistant and extensively drug-resistant tuberculosis, Japan.

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Title: Effect of D-cycloserine on spatial learning performance and memory function-related gene expression in mice following toluene exposure.

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Title: 3'-bromo analogues of pyrimidine nucleosides as a new class of potent inhibitors of Mycobacterium tuberculosis.

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Title: Extensively drug-resistant tuberculosis treatment outcome in Iran: a case series of seven patients.

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Title: Glutamatergic modulatory therapy for Tourette syndrome.

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Title: The role of NMDA receptors in the signal attenuation rat model of obsessive-compulsive disorder.

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Title: Extensively drug-resistant tuberculosis, Burkina Faso.

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Title: D-cycloserine inhibits the development and the expression of locomotor sensitization to amphetamine in rats.

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Title: Chiral discrimination among aminotransferases: inactivation by 4-amino-4,5-dihydrothiophenecarboxylic acid.

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Title: High efficacy of clofazimine and its synergistic effect with amikacin against rapidly growing mycobacteria.

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Title: Clostridium difficile in ground meat, France.

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Title: Update on the management of antibiotic allergy.

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Title: Human infections due to Mycobacterium lentiflavum: first report in Iran.

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Title: D-cycloserine deters reacquisition of cocaine self-administration by augmenting extinction learning.

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Title: A liquid chromatography-tandem mass spectrometry assay for Marfey's derivatives of L-Ala, D-Ala, and D-Ala-D-Ala: application to the in vivo confirmation of alanine racemase as the target of cycloserine in Escherichia coli.

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Title: D-cycloserine facilitates extinction of naloxone-induced conditioned place aversion in morphine-dependent rats.

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Title: Sequential bilateral lung resection in a patient with Mycobacterium abscessus lung disease refractory to medical treatment.

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Title: Propranolol and D-cycloserine as adjunctive medications in reducing dental fear in sedation practice.

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Title: What is schizophrenia: A neurodevelopmental or neurodegenerative disorder or a combination of both? A critical analysis.

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Title: Risk factors for MDR and XDR-TB in a tertiary referral hospital in India.

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Title: Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi-drug resistant tuberculosis: a case report.

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Title: Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation.

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Title: Conjugative botulinum neurotoxin-encoding plasmids in Clostridium botulinum.

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Title: Cholesterol-lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings.

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Title: Multiple osseous involvements in a case of disseminated cryptococcosis.

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Title: Isoniazid resistance and death in patients with tuberculous meningitis: retrospective cohort study.

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Title: Pharmacological enhancement of behavioral therapy: focus on posttraumatic stress disorder.

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Title: Characterization and evaluation of the directly observed treatment for tuberculosis in Santiago de Compostela (1996-2006).

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Title: Complete genome sequence of Pirellula staleyi type strain (ATCC 27377).

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Title: Object location memory in mice: pharmacological validation and further evidence of hippocampal CA1 participation.

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Title: Emerging treatments for PTSD.

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Title: Violacein-producing Collimonas sp. from the sea surface microlayer of costal waters in Trøndelag, Norway.

Journal: Marine drugs 20091201

Title: Trends in Mycobacterium tuberculosis resistance, Pakistan, 1990-2007.

Journal: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20091101

Title: A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein.

Journal: Molecular microbiology 20091101

Title: Pharmacological discrimination of extinction and reconsolidation of contextual fear memory by a potentiator of AMPA receptors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091101

Title: Rapid reversal of hyperpigmentation in pityriasis versicolor upon short-term topical cycloserine application.

Journal: Mycoses 20091101

Title: Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting.

Journal: Nature chemical biology 20091101

Title: Long-chain ceramide produced in response to N-hexanoylsphingosine does not induce apoptosis in CHP-100 cells.

Journal: Lipids 20091101

Title: D-cycloserine into the BLA reverses the impairing effects of exposure to stress on the extinction of contextual fear, but not conditioned taste aversion.

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Title: D-cycloserine facilitation of fear extinction and exposure-based therapy might rely on lower-level, automatic mechanisms.

Journal: Biological psychiatry 20091001

Title: D-Cycloserine attenuates reactivity to smoking cues in nicotine dependent smokers: a pilot investigation.

Journal: Drug and alcohol dependence 20091001

Title: Prevalence of extensively drug-resistant tuberculosis in Vladimir and Orel regions, Russia.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20091001

Title: An fMRI study examining effects of acute D-cycloserine during symptom provocation in spider phobia.

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Title: Social phobia: an update on treatment.

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Title: Pharmacokinetics of prothionamide in patients with multidrug-resistant tuberculosis.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20090901

Title: Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex.

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Title: The ameliorating effects of NMDA receptor agonists on histamine H1 antagonist-induced memory and hippocampal theta disruptions are prevented by the H3 receptor agonist in rats.

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Title: Emergence of new forms of totally drug-resistant tuberculosis bacilli: super extensively drug-resistant tuberculosis or totally drug-resistant strains in iran.

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Title: Psychotherapy for obsessive-compulsive disorder.

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Title: Seven-year DOTS-Plus pilot experience in India: results, constraints and issues.

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Title: Characteristics of sulfobacin A from a soil isolate Chryseobacterium gleum.

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Title: An improved isolation method for attached-living Planctomycetes of the genus Rhodopirellula.

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Title: Extensively drug-resistant tuberculosis in the UK: 1995 to 2007.

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Title: D-cycloserine accelerates the extinction of cocaine-induced conditioned place preference in C57bL/c mice.

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Title: Co-infection with pansensitive and multidrug-resistant strains of Mycobacterium tuberculosis.

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Title: Variant BDNF Val66Met polymorphism affects extinction of conditioned aversive memory.

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Title: A novel assay of bacterial peptidoglycan synthesis for natural product screening.

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Title: ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds.

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Title: D-cycloserine enhances short-delay, but not long-delay, conditioned taste aversion learning in rats.

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Title: Identification of aquaporin 4 inhibitors using in vitro and in silico methods.

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Title: The NMDA agonist D-cycloserine facilitates fear memory consolidation in humans.

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Title: Transcript and metabolite profiling of the adaptive response to mild decreases in oxygen concentration in the roots of arabidopsis plants.

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Title: The facilitative effects of D-cycloserine on extinction of a cocaine-induced conditioned place preference can be long lasting and resistant to reinstatement.

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Title: Facilitation of extinction of operant behaviour in mice by D-cycloserine.

Journal: Psychopharmacology 20090101

Title: Effects of D-cycloserine administration on weekly nonemotional memory tasks in healthy participants.

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Title: D-cycloserine potentiates the reconsolidation of cocaine-associated memories.

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Title: [Optimization of chemotherapy regimens in children with primary pulmonary tuberculosis].

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Title: [The research network PANIC-NET: improving the treatment of panic disorder - from a better understanding of fear circuit mechanisms to more effective psychological treatment and routine care].

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Title: [The course of a process and the efficiency of treatment of pulmonary tuberculosis patients excreting Mycobacterium tuberculosis with extensive drug resistance to antituberculous drugs].

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Title: Early postnatal stress and neural circuit underlying emotional regulation.

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Title: Early outcomes of MDR-TB treatment in a high HIV-prevalence setting in Southern Africa.

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Title: Ambulatory-based standardized therapy for multi-drug resistant tuberculosis: experience from Nepal, 2005-2006.

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Title: Current perspectives in the treatment of resistant schizophrenia.

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Title: Prosthetic Joint Infection due to Mycobacterium bovis after Intravesical Instillation of Bacillus Calmette-Guerin (BCG).

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Title: Augmentation of fear extinction by D-cycloserine is blocked by proteasome inhibitors.

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Title: A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral-CA1 synapses in hippocampus.

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Title: Second-line drug resistance in multidrug-resistant tuberculosis cases of various origins in the Netherlands.

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Title: D-cycloserine facilitates context-specific fear extinction learning.

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Title: Extensively drug-resistant Mycobacterium tuberculosis during a trend of decreasing drug resistance from 2000 through 2006 at a Medical Center in Taiwan.

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Title: Effects of single prolonged stress and D-cycloserine on contextual fear extinction and hippocampal NMDA receptor expression in a rat model of PTSD.

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Title: D-cycloserine augmentation for behavioral therapy.

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Title: A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy.

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Title: Glycine and D: -serine, but not D: -cycloserine, attenuate prepulse inhibition deficits induced by NMDA receptor antagonist MK-801.

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Title: Extensively drug-resistant tuberculosis, Lesotho.

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Title: Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome induced by celecoxib and anti-tuberculosis drugs.

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Title: Early postnatal stress alters the extinction of context-dependent conditioned fear in adult rats.

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Title: Extensively drug-resistant tuberculosis, Taiwan.

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Title: Activity of twelve second-line antimicrobial agents against Mycobacterium tuberculosis in Taiwan.

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Title: A randomized controlled trial of D-cycloserine enhancement of exposure therapy for social anxiety disorder.

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Title: Effects of D-cycloserine on the behavior and ERK activity in the amygdala: role of individual anxiety levels.

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Title: Learning and memory in conditioned fear extinction: effects of D-cycloserine.

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Title: Participation of hippocampal ionotropic glutamate receptors in histamine H(1) antagonist-induced memory deficit in rats.

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Title: Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder.

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Title: Critical parameters for D-cycloserine enhancement of cognitive-behaviorial therapy for obsessive-compulsive disorder.

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Title: Mycobacterium xenopi clinical relevance and determinants, the Netherlands.

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Title: Antibiotic-associated diarrhea: candidate organisms other than Clostridium difficile.

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Title: Cycloserine.

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Title: Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.

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Title: Abnormally persistent latent inhibition induced by MK801 is reversed by risperidone and by positive modulators of NMDA receptor function: differential efficacy depending on the stage of the task at which they are administered.

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Title: Effects of REM deprivation and an NMDA agonist on the extinction of conditioned fear.

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Title: Absence of significant interactive effects of high-dose D-cycloserine and ethanol in healthy human subjects: preliminary insights into ethanol actions at the glycine B site of NMDA glutamate receptors.

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Title: Outcome of multi-drug resistant tuberculosis cases treated by individualized regimens at a tertiary level clinic.

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Title: Reliable identification of mycobacterial species by PCR-restriction enzyme analysis (PRA)-hsp65 in a reference laboratory and elaboration of a sequence-based extended algorithm of PRA-hsp65 patterns.

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Title: Limited impact of homeostatic plasticity on motor learning in humans.

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Title: The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase.

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Title: Extensively drug resistant tuberculosis in a high income country: a report of four unrelated cases.

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Title: Coexistence of primary adenocarcinoma of the lung and Tsukamurella infection: a case report and review of the literature.

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Title: Development of a liposome formulation for D-cycloserine local delivery.

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Title: Tuberculous meningitis presenting with unusual clinical features in Nigerians: Two case reports.

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Title: D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in rats.

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Title: Immunization against Clostridium perfringens cells elicits protection against Clostridium tetani in mouse model: identification of cross-reactive proteins using proteomic methodologies.

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Title: [Russian cycloserine in complex therapy of drug resistant tuberculosis].

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Title: targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.

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Title: Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance.

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Title: Genotyping and drug resistance patterns of M. tuberculosis strains in Pakistan.

Journal: BMC infectious diseases 20080101

Title: [Rezonizat and cycloserine in complex therapy of drug resistant tuberculosis (comparative studies)].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20080101

Title: Dizocilpine-induced accuracy deficits in a visual signal detection task are not present following D-cycloserine administration in rats.

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Title: Use of NMR metabolomics to analyze the targets of D-cycloserine in mycobacteria: role of D-alanine racemase.

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Title: Prevalence, haemolytic and haemagglutination activities and antibiotic susceptibility profiles of Campylobacter spp. isolated from human diarrhoeal stools in Vhembe District, South Africa.

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Title: Effects of D-cycloserine on extinction: consequences of prior exposure to imipramine.

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Title: D-cycloserine reduces neuropathic pain behavior through limbic NMDA-mediated circuitry.

Journal: Pain 20071101

Title: Effect of L-cycloserine on cellular responses mediated by macrophages and T cells.

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Title: Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms.

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Title: N-methyl-D-aspartate receptors and amnesia in mice with depression-like state.

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Title: D-cycloserine augmented exposure therapy for obsessive-compulsive disorder.

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Title: Neuroplasticity as a target for the pharmacotherapy of psychiatric disorders: new opportunities for synergy with psychotherapy.

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Title: The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments.

Journal: The American journal of psychiatry 20071001

Title: Involvement of astroglial ceramide in palmitic acid-induced Alzheimer-like changes in primary neurons.

Journal: The European journal of neuroscience 20071001

Title: A randomized controlled trial of the effect of D-cycloserine on exposure therapy for spider fear.

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Title: NMDA receptor modulation by D-cycloserine promotes episodic-like memory in mice.

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Title: D-Cycloserine and performance under different states of anxiety in healthy volunteers.

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Title: Enhancing exposure-based therapy from a translational research perspective.

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Title: Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins.

Journal: Nature chemical biology 20070901

Title: Roles of hippocampal N-methyl-D-aspartate receptors and calcium/calmodulin-dependent protein kinase II in amphetamine-produced conditioned place preference in rats.

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Title: D-cycloserine inhibits amygdala responses during repeated presentations of faces.

Journal: CNS spectrums 20070801

Title: Drug resistance rates of Mycobacterium tuberculosis at a private referral center in Korea.

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Title: Mechanisms of exposure therapy: how neuroscience can improve psychological treatments for anxiety disorders.

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Title: D-cycloserine improves functional recovery and reinstates long-term potentiation (LTP) in a mouse model of closed head injury.

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Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20070701

Title: D-cycloserine does not enhance exposure-response prevention therapy in obsessive-compulsive disorder.

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Title: D-Cycloserine enhances memory consolidation of hippocampus-dependent latent extinction.

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Title: The application of exposure therapy and D-cycloserine to the treatment of anorexia nervosa: a preliminary trial.

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Title: [Case of pulmonary multi-drug resistant tuberculosis with left destroyed lung, treated with pneumonectomy].

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Title: Effects of activation and blockade of NMDA receptors on the extinction of a conditioned passive avoidance response in mice with different levels of anxiety.

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Title: Effects of D-cycloserine on extinction of learned fear to an olfactory cue.

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Title: Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.

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Title: Treatment for anxiety-related disorders.

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Title: A randomized controlled trial of the effect of D-cycloserine on extinction and fear conditioning in humans.

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Title: Antibiotic resistance of lactic acid bacteria and Bifidobacterium spp. isolated from dairy and pharmaceutical products.

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Title: Diazenedicarboxamides as inhibitors of D-alanine-D-alanine ligase (Ddl).

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Title: Deficit of NMDA receptor activation in CA1 hippocampal area of aged rats is rescued by D-cycloserine.

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Title: Spread of extensively drug-resistant tuberculosis.

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Title: NMDA Partial agonist reverses blocking of extinction of aversive memory by GABA(A) agonist in the amygdala.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301

Title: Characterisation of the human NMDA receptor subunit NR3A glycine binding site.

Journal: Neuropharmacology 20070301

Title: NMDA receptor in conditioned flavor-taste preference learning: blockade by MK-801 and enhancement by D-cycloserine.

Journal: Pharmacology, biochemistry, and behavior 20070301

Title: Worldwide emergence of extensively drug-resistant tuberculosis.

Journal: Emerging infectious diseases 20070301

Title: Expression, activity, and role of serine palmitoyltransferase in the rat hippocampus after kainate injury.

Journal: Journal of neuroscience research 20070201

Title: Clinical perspectives on the combination of D-cycloserine and cognitive-behavioral therapy for the treatment of anxiety disorders.

Journal: CNS spectrums 20070101

Title: Glutamate-modulating drugs & the treatment of mental disorders.

Journal: Journal of psychosocial nursing and mental health services 20070101

Title: [A case of multidrug-resistant pulmonary tuberculosis cured by the regimen including thiacetazone].

Journal: Kekkaku : [Tuberculosis] 20070101

Title: Medical post-traumatic stress disorder: catching up with the cutting edge in stress research.

Journal: Critical care (London, England) 20070101

Title: [Tryptose sulphite cycloserine agar for the recovery of Clostridium perfringens in surface waters: a study of different modes of utilization].

Journal: Annali di igiene : medicina preventiva e di comunita 20070101

Title: D-Cycloserine enhances conditioned taste aversion learning in rats.

Journal: Pharmacology, biochemistry, and behavior 20070101

Title: Susceptibility tests to second line drugs and re-treatment of tuberculosis revisiting early experiences.

Journal: Medicina 20070101

Title: Selective increase in the extracellular D-serine contents by D-cycloserine in the rat medial frontal cortex.

Journal: Neurochemistry international 20070101

Title: Multidrug-resistant tuberculosis treatment outcomes in Karakalpakstan, Uzbekistan: treatment complexity and XDR-TB among treatment failures.

Journal: PloS one 20070101

Title: Audiologic monitoring of multi-drug resistant tuberculosis patients on aminoglycoside treatment with long term follow-up.

Journal: BMC ear, nose, and throat disorders 20070101

Title: Tricarboxylic acid cycle intermediate pool size: functional importance for oxidative metabolism in exercising human skeletal muscle.

Journal: Sports medicine (Auckland, N.Z.) 20070101

Title: Genetic characterization of psp encoding the DING protein in Pseudomonas fluorescens SBW25.

Journal: BMC microbiology 20070101

Title: Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

Journal: PloS one 20070101

Title: Extensively drug-resistant tuberculosis (XDR-TB) - a potential threat in Ireland.

Journal: The open respiratory medicine journal 20070101

Title: Delay aversion: effects of 7-OH-DPAT, 5-HT1A/1B-receptor stimulation and D-cycloserine.

Journal: Pharmacology, biochemistry, and behavior 20061201

Title: Influence of ethanol withdrawal on fear memory: Effect of D-cycloserine.

Journal: Neuroscience 20061103

Title: D-cycloserine facilitates extinction but does not eliminate renewal of the conditioned emotional response.

Journal: Behavioral neuroscience 20061001

Title: Reconsolidation and extinction of conditioned fear: inhibition and potentiation.

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Title: d-Cycloserine facilitates extinction of a cocaine-induced conditioned place preference.

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Title: Antituberculous therapy-induced fulminant hepatic failure: successful treatment with liver transplantation and nonstandard antituberculous therapy.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20060901

Title: Multidrug-resistant tuberculosis management in resource-limited settings.

Journal: Emerging infectious diseases 20060901

Title: Extinction training in conjunction with a partial agonist of the glycine site on the NMDA receptor erases memory trace.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060830

Title: Effects of D-cycloserine on extinction: translation from preclinical to clinical work.

Journal: Biological psychiatry 20060815

Title: [A case of pulmonary Mycobacterium fortuitum infection successfully treated with Kampo treatments].

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Title: Equilibrium in lung schistosomula sphingomyelin breakdown and biosynthesis allows very small molecules, but not antibody, to access proteins at the host-parasite interface.

Journal: The Journal of parasitology 20060801

Title: Controlled trial of D-cycloserine adjuvant therapy for treatment-resistant major depressive disorder.

Journal: Journal of affective disorders 20060701

Title: [Treatment outcome of patients with multidrug-resistant pulmonary tuberculosis during pregnancy].

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Title: Molecular dynamics simulations of the ligand-binding domain of an N-methyl-D-aspartate receptor.

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Title: Ceramide is a mediator of apoptosis in retina photoreceptors.

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Title: Multidrug-resistant tuberculosis without HIV infection: success with individualised therapy.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20060401

Title: [Tuberculosis miliar in a patient treated with intravesical instillations of bacillus Calmette-Guérin].

Journal: Medicina intensiva 20060401

Title: Characterization of cycA mutants of Escherichia coli. An assay for measuring in vivo mutation rates.

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Title: The occurrence of free D-alanine and an alanine racemase activity in Leishmania amazonensis.

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Title: Augmentation of exposure therapy with D-cycloserine for social anxiety disorder.

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Title: Pulmonary Mycobacterium kansasii infection in Israel, 1999-2004: clinical features, drug susceptibility, and outcome.

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Title: Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients.

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Title: [Influence of activation and blockade of NMDA receptors on extinction of passive avoidance response in mice with different levels of anxiety].

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Title: API TB Consensus Guidelines 2006: Management of pulmonary tuberculosis, extra-pulmonary tuberculosis and tuberculosis in special situations.

Journal: The Journal of the Association of Physicians of India 20060301

Title: Multidrug-resistant tuberculous spondylodiscitis: need for aggressive management and drug susceptibility testing of Mycobacterium tuberculosis isolates.

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Title: Mycobacterium haemophilum osteomyelitis: case report and review of the literature.

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Title: [The rates of resistance to second-line drugs in multidrug resistant Mycobacterium tuberculosis strains].

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Title: CIMT as a behavioral engine in research on physiological adjuvants to neurorehabilitation: the challenge of merging animal and human research.

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Title: Augmentation treatment of psychotherapy for anxiety disorders with D-cycloserine.

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Title: Efficacy and safety of kanamycin, ethionamide, PAS and cycloserine in multidrug-resistant pulmonary tuberculosis patients.

Journal: The Indian journal of chest diseases & allied sciences 20060101

Title: Stimulation of mutagenesis by proportional deoxyribonucleoside triphosphate accumulation in Escherichia coli.

Journal: DNA repair 20051208

Title: GLYX-13: a monoclonal antibody-derived peptide that acts as an N-methyl-D-aspartate receptor modulator.

Journal: Neuropharmacology 20051201

Title: Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands.

Journal: Psychopharmacology 20051201

Title: An ionotropic but not a metabotropic glutamate agonist potentiates the pharmacological effects of olanzapine in the rat.

Journal: Behavioural pharmacology 20051201

Title: Diagnosis and treatment of nontuberculous mycobacterial pulmonary diseases: a Korean perspective.

Journal: Journal of Korean medical science 20051201

Title: Mycobacterium kansasii pulmonary diseases in Korea.

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Title: The activity reaction core and plasticity of metabolic networks.

Journal: PLoS computational biology 20051201

Title: Treatment of multiple drug-resistant tuberculosis (MDR-TB) in Iran.

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Title: Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates.

Journal: Antimicrobial agents and chemotherapy 20051101

Title: Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates.

Journal: Journal of medical microbiology 20051001

Title: Diagnostic and therapeutic problems of pulmonary tuberculosis in elderly patients.

Journal: Journal of Korean medical science 20051001

Title: Emotional learning and glutamate: translational perspectives.

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Title: Apical uptake and transepithelial transport of sphingosine monomers through intact human intestinal epithelial cells: physicochemical and molecular modeling studies.

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Title: Characterization of Chlamydia MurC-Ddl, a fusion protein exhibiting D-alanyl-D-alanine ligase activity involved in peptidoglycan synthesis and D-cycloserine sensitivity.

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Title: Genomic fingerprinting of antituberculosis agents-resistant Lactobacillus ruminus SPM0211 using the Microbial Uniprimer kit.

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Title: An acute decrease in TCA cycle intermediates does not affect aerobic energy delivery in contracting rat skeletal muscle.

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Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

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Title: Behavioral effects of d-cycloserine in rats: the role of anxiety level.

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Title: Effects of multiple exposures to D-cycloserine on extinction of conditioned fear in rats.

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Title: D-cycloserine facilitates extinction of learned fear: effects on reacquisition and generalized extinction.

Journal: Biological psychiatry 20050415

Title: Effect of a Y265F mutant on the transamination-based cycloserine inactivation of alanine racemase.

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Title: A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients.

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Title: Mycobacterium tuberculosis drug resistance, Abkhazia.

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Title: Treating early psychosis: who, what, and when?

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Title: Multidrug-resistant tuberculosis in Russia: clinical characteristics, analysis of second-line drug resistance and development of standardized therapy.

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Title: Psychosocial approaches of acute stress reactions.

Journal: CNS spectrums 20050201

Title: Treatment outcome of multidrug-resistant tuberculosis among Vietnamese immigrants.

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Title: Functional magnetic resonance imaging studies of schizophrenic patients during word production: effects of D-cycloserine.

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Title: Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis.

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Title: Inhibition of sphingolipid biosynthesis decreases phosphorylated ERK2 in LLC-PK1 cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101

Title: Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).

Journal: British journal of pharmacology 20050101

Title: Mycobacterium lentiflavum infection in immunocompetent patient.

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Title: Cognitive-behavioral therapy and the treatment of panic disorder: efficacy and strategies.

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Title: Facilitation of conditioned fear extinction by d-cycloserine is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase cascades and requires de novo protein synthesis in basolateral nucleus of amygdala.

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Title: Suicides in general hospitals.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20041201

Title: A pilot study of D-cycloserine in subjects with autistic disorder.

Journal: The American journal of psychiatry 20041101

Title: Cognitive enhancers as adjuncts to psychotherapy: use of D-cycloserine in phobic individuals to facilitate extinction of fear.

Journal: Archives of general psychiatry 20041101

Title: Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine.

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Title: Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.

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Title: Multidrug resistant miliary tuberculosis and Pott's disease in an immunocompetent patient.

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Title: Differential neuroprotective effects of the NMDA receptor-associated glycine site partial agonists 1-aminocyclopropanecarboxylic acid (ACPC) and D-cycloserine in lithium-pilocarpine status epilepticus.

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Title: Cell-surface alterations in class IIa bacteriocin-resistant Listeria monocytogenes strains.

Journal: Microbiology (Reading, England) 20040901

Title: Consolidation of human motor cortical neuroplasticity by D-cycloserine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040801

Title: Pharmacotherapy for performance anxiety disorders: occasionally useful but typically contraindicated.

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Title: Pharmacy data for tuberculosis surveillance and assessment of patient management.

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Title: Responsiveness to brightness change in male and female rats following treatment with the partial agonist of the N-methyl-D-aspartate receptor, D-cycloserine.

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Journal: Behavioral neuroscience 20040601

Title: Psychiatric issues in the management of patients with multidrug-resistant tuberculosis.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040601

Title: Surveillance of Mycobacterium tuberculosis susceptibility to second-line drugs in Hong Kong, 1995-2002, after the implementation of DOTS-plus.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040601

Title: Treatment and follow-up of HIV-negative multidrug-resistant tuberculosis patients in an infectious diseases reference hospital, Buenos Aires, Argentina.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040601

Title: Ceramide synthesis correlates with the posttranscriptional regulation of the sterol-regulatory element-binding protein.

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Title: Glycine and D-cycloserine attenuate vacuous chewing movements in a rat model of tardive dyskinesia.

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Title: Six-month therapy with aerosolized interferon-gamma for refractory multidrug-resistant pulmonary tuberculosis.

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Title: Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands.

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Title: Effects of NMDA receptor-related agonists on learning and memory impairment in olfactory bulbectomized mice.

Journal: Methods and findings in experimental and clinical pharmacology 20040301

Title: Self-administered, standardized regimens for multidrug-resistant tuberculosis in South Korea.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040301

Title: Surprises and omissions in toxicology.

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Title: Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.

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Title: Comparative effects of glycine and D-cycloserine on persistent negative symptoms in schizophrenia: a retrospective analysis.

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Title: A microplate indicator-based method for determining the susceptibility of multidrug-resistant Mycobacterium tuberculosis to antimicrobial agents.

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Title: New agents active against Mycobacterium avium complex selected by molecular topology: a virtual screening method.

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Title: Facilitation of fear extinction by D-cycloserine: theoretical and clinical implications.

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Title: Pharmacokinetics and relative bioavailability of clofazimine in relation to food, orange juice and antacid.

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Title: Bacteriological investigation of infectious keratoconjunctivitis in Norwegian sheep.

Journal: Acta veterinaria Scandinavica 20040101

Title: First documented cure of a suggestive exogenous reinfection in polymyositis with same but multidrug resistant M. tuberculosis.

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Title: Cycloserine and threo-dihydrosphingosine inhibit TNF-alpha-induced cytotoxicity: evidence for the importance of de novo ceramide synthesis in TNF-alpha signaling.

Journal: Biochimica et biophysica acta 20031207

Title: In vitro activity of C-8-methoxy fluoroquinolones against mycobacteria when combined with anti-tuberculosis agents.

Journal: The Journal of antimicrobial chemotherapy 20031201

Title: Society for Neuroscience meeting. Pills and games help conquer fear.

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Title: D-cycloserine facilitates synaptic plasticity but impairs glutamatergic neurotransmission in rat hippocampal slices.

Journal: British journal of pharmacology 20031101

Title: Genome-wide transcriptional profiling of the response of Staphylococcus aureus to cell-wall-active antibiotics reveals a cell-wall-stress stimulon.

Journal: Microbiology (Reading, England) 20031001

Title: Comparative roles of levofloxacin and ofloxacin in the treatment of multidrug-resistant tuberculosis: preliminary results of a retrospective study from Hong Kong.

Journal: Chest 20031001

Title: Molecular cloning of a D-cycloserine resistance gene from D-cycloserine-producing Streptomyces garyphalus.

Journal: The Journal of antibiotics 20030901

Title: Substrate reduction intervention by L-cycloserine in twitcher mice (globoid cell leukodystrophy) on a B6;CAST/Ei background.

Journal: Neuroscience letters 20030814

Title: D-cycloserine-Naloxone interactions in opioid-dependent humans under a novel-response naloxone discrimination procedure.

Journal: Experimental and clinical psychopharmacology 20030801

Title: Multidrug-resistant tuberculosis in HIV-negative patients, Buenos Aires, Argentina.

Journal: Emerging infectious diseases 20030801

Title: Effects of antibiotics that inhibit the bacterial peptidoglycan synthesis pathway on moss chloroplast division.

Journal: Plant & cell physiology 20030701

Title: Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core.

Journal: The EMBO journal 20030616

Title: D-cycloserine for the treatment of ataxia in spinocerebellar degeneration.

Journal: Journal of the neurological sciences 20030615

Title: A side reaction of alanine racemase: transamination of cycloserine.

Journal: Biochemistry 20030520

Title: Subunit interaction of monomeric alanine racemases from four Shigella species in catalytic reaction.

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Title: Effects of dietary sphingomyelin on central nervous system myelination in developing rats.

Journal: Pediatric research 20030401

Title: Effects of D-cycloserine on extinction of conditioned freezing.

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Title: Multidrug-resistant tuberculosis in pregnancy: case report and review of the literature.

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Title: The decline of high drug resistance rate of pulmonary Mycobacterium tuberculosis isolates from a southern Taiwan medical centre, 1996-2000.

Journal: International journal of antimicrobial agents 20030301

Title: [14C]serine from phosphatidylserine labels ceramide and sphingomyelin in L929 cells: evidence for a new metabolic relationship between glycerophospholipids and sphingolipids.

Journal: Archives of biochemistry and biophysics 20030201

Title: N(2)-substituted D,L-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors.

Journal: The Journal of antibiotics 20030201

Title: Novel antibiotic-resistance markers in pGK12-derived vectors for Borrelia burgdorferi.

Journal: Gene 20030116

Title: Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug-resistant Mycobacterium tuberculosis infection in BALB/c mice.

Journal: Antimicrobial agents and chemotherapy 20030101

Title: [Incidence of adverse reactions to chemotherapy and their types in adolescents with tuberculosis].

Journal: Problemy tuberkuleza 20030101

Title: Ceramide signaling in fenretinide-induced endothelial cell apoptosis.

Journal: The Journal of biological chemistry 20021220

Title: Homer 1a gene expression modulation by antipsychotic drugs: involvement of the glutamate metabotropic system and effects of D-cycloserine.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021201

Title: Pilot-controlled trial of D-cycloserine for the treatment of post-traumatic stress disorder.

Journal: The international journal of neuropsychopharmacology 20021201

Title: Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme.

Journal: Structure (London, England : 1993) 20021101

Title: Molecular epidemiology of tuberculosis in a sentinel surveillance population.

Journal: Emerging infectious diseases 20021101

Title: Molecular epidemiology of multidrug-resistant tuberculosis, New York City, 1995-1997.

Journal: Emerging infectious diseases 20021101

Title: Direct calcium binding results in activation of brain serine racemase.

Journal: The Journal of biological chemistry 20020802

Title: D-Cycloserine added to risperidone in patients with primary negative symptoms of schizophrenia.

Journal: Schizophrenia research 20020701

Title: Evidence for de novo sphingolipid biosynthesis in Toxoplasma gondii.

Journal: International journal for parasitology 20020601

Title: Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid.

Journal: Acta physiologica Scandinavica 20020501

Title: [Pharmacological support of exposure therapy in anxiety disorders. Animal experiment studies].

Journal: Der Nervenarzt 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis.

Journal: The Biochemical journal 20020401

Title: Cycloserine fatty acid derivatives as prodrugs: synthesis, degradation and in vitro skin permeability.

Journal: Chemical & pharmaceutical bulletin 20020401

Title: Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020315

Title: Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia.

Journal: The American journal of psychiatry 20020301

Title: A pathway-specific cell based screening system to detect bacterial cell wall inhibitors.

Journal: The Journal of antibiotics 20020301

Title: Impaired visual memory in rats reared in isolation is reversed by D-cycloserine in the adult rat.

Journal: European journal of pharmacology 20020215

Title: Effects of scopolamine and D-cycloserine on non-spatial reference memory in rats.

Journal: Behavioural brain research 20020201

Title: Substrate-reduction therapy enhances the benefits of bone marrow transplantation in young mice with globoid cell leukodystrophy.

Journal: Pediatric research 20020101

Title: D-cycloserine for Alzheimer's disease.

Journal: The Cochrane database of systematic reviews 20020101

Title: Therapeutic drug monitoring in the treatment of tuberculosis.

Journal: Drugs 20020101

Title: [Effect of glutoxim in the combination with antitubercular agents of the second choice on the growth of drug resistant Mycobacteria tuberculosis in the cultured murine lung tissue].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101

Title: A case series of D-cycloserine added to donepezil in the treatment of Alzheimer's disease.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20020101

Title: Can cyclosporine go it alone in severe ulcerative colitis?

Journal: Current gastroenterology reports 20011201

Title: Role of specific aminotransferases in de novo glutamate synthesis and redox shuttling in the retina.

Journal: Journal of neuroscience research 20011201

Title: [Treatment outcomes of multidrug-resistant tuberculosis--comparison between success and failure cases].

Journal: Kekkaku : [Tuberculosis] 20011201

Title: Involvement of cholinergic and glutamatergic functions in working memory impairment induced by interleukin-1beta in rats.

Journal: European journal of pharmacology 20011102

Title: Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR.

Journal: Antimicrobial agents and chemotherapy 20011101

Title: Pharmacokinetics of para-aminosalicylic acid granules under four dosing conditions.

Journal: The Annals of pharmacotherapy 20011101

Title: Determination of cycloserine in human plasma by high-performance liquid chromatography with fluorescence detection, using derivatization with p-benzoquinone.

Journal: Journal of chromatography. B, Biomedical sciences and applications 20010915

Title: RS 67333 and D-cycloserine accelerate learning acquisition in the rat.

Journal: Neuropharmacology 20010901

Title: Effects of N-methyl-D-aspartate agonists and antagonists in rats discriminating amphetamine.

Journal: Behavioural pharmacology 20010901

Title: Therapeutic approaches to age-associated neurocognitive disorders.

Journal: Dialogues in clinical neuroscience 20010901

Title: Subunit specificity and mechanism of action of NMDA partial agonist D-cycloserine.

Journal: Neuropharmacology 20010801

Title: Pharmacokinetics of cycloserine under fasting conditions and with high-fat meal, orange juice, and antacids.

Journal: Pharmacotherapy 20010801

Title: Possible mechanisms for the relative efficacies of ortho-phthalaldehyde and glutaraldehyde against glutaraldehyde-resistant Mycobacterium chelonae.

Journal: Journal of applied microbiology 20010701

Title: Phencyclidine impairs latent learning in mice: interaction between glutamatergic systems and sigma(1) receptors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010401

Title: Utility of PCR assays for rapid diagnosis of BCG infection in children.

Journal: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20010401

Title: [A case of drug-resistant pulmonary tuberculosis treated successfully following disappearance of rifampicin resistance after 17 years' chemotherapy].

Journal: Kekkaku : [Tuberculosis] 20010401

Title: Synergic activity of D-cycloserine and beta-chloro-D-alanine against Mycobacterium tuberculosis.

Journal: The Journal of antimicrobial chemotherapy 20010201

Title: The role of fluoroquinolones in tuberculosis today.

Journal: Drugs 20010101

Title: Pathological apoptosis by xanthurenic acid, a tryptophan metabolite: activation of cell caspases but not cytoskeleton breakdown.

Journal: BMC physiology 20010101

Title: Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein.

Journal: Oncology research 20010101

Title: Mutant prevention concentration as a measure of antibiotic potency: studies with clinical isolates of Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 20000901

Title: Characterization of a fish antimicrobial peptide: gene expression, subcellular localization, and spectrum of activity.

Journal: Antimicrobial agents and chemotherapy 20000801

Title: Effects of the partial glycine agonist D-cycloserine on cognitive functioning in chronic low dose MPTP-treated monkeys.

Journal: Brain research 20000331

Title: Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs.

Journal: Biochemical pharmacology 20000201

Title: Development of a firefly luciferase-based assay for determining antimicrobial susceptibility of Mycobacterium avium subsp. paratuberculosis.

Journal: Journal of clinical microbiology 19990201

Title: Mechanism of resistance to amikacin and kanamycin in Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 19980501

Title: Green fluorescent protein reporter microplate assay for high-throughput screening of compounds against Mycobacterium tuberculosis.

Journal: Antimicrobial agents and chemotherapy 19980201

Title: Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium.

Journal: Antimicrobial agents and chemotherapy 19970501

Title: Effects of D-cycloserine and aniracetam on spatial learning in rats with entorhinal cortex lesions.

Journal: Pharmacology, biochemistry, and behavior 19970101

Title: In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages.

Journal: Current microbiology 19960901

Title: Susceptibility testing of Mycobacterium avium complex isolates.

Journal: Antimicrobial agents and chemotherapy 19960801

Title: Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery.

Journal: Antimicrobial agents and chemotherapy 19960601

Title: L-cycloserine, an inhibitor of sphingolipid biosynthesis, inhibits HIV-1 cytopathic effects, replication, and infectivity.

Journal: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 19960201

Title: The severity of naloxone-precipitated opiate withdrawal is attenuated by felbamate, a possible glycine antagonist.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19951201

Title: Susceptibilities of nontuberculosis mycobacterial species to amoxicillin-clavulanic acid alone and in combination with antimycobacterial agents.

Journal: Antimicrobial agents and chemotherapy 19950701

Title: Mycobacterium avium strains resistant to clarithromycin and azithromycin.

Journal: Antimicrobial agents and chemotherapy 19931101

Title: Adverse neurological reactions in patients with multidrug-resistant pulmonary tuberculosis after coadministration of cycloserine and ofloxacin.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 19930801

Title: Spectrum of drugs against atypical mycobacteria: how valid is the current practice of drug susceptibility testing and the choice of drugs?

Journal: Zentralblatt fur Bakteriologie : international journal of medical microbiology 19921201

Title: Fluorocontaining D-cycloserines. Synthesis and in vitro evaluation of antimicrobial and antiviral activities.

Journal: Farmaco (Societa chimica italiana : 1989) 19920601

Title: Effects of D-cycloserine and cycloleucine, ligands for the NMDA-associated strychnine-insensitive glycine site, on brain-stimulation reward and spontaneous locomotion.

Journal: Pharmacology, biochemistry, and behavior 19900801

Title: Comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria.

Journal: The Journal of antimicrobial chemotherapy 19881001

Title: Qualitative and quantitative drug-susceptibility tests in mycobacteriology.

Journal: The American review of respiratory disease 19880501

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Tags:68-41-7 Molecular Formula|68-41-7 MDL|68-41-7 SMILES|68-41-7 (4R)-4-amino-1,2-oxazolidin-3-one