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6981-18-6,MFCD00057747
Catalog No.:AA00IBWU

6981-18-6 | Ormetoprim

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100mg
98%
in stock  
$32.00   $22.00
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1g
98%
in stock  
$128.00   $90.00
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5g
98%
in stock  
$427.00   $299.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IBWU
Chemical Name:
Ormetoprim
CAS Number:
6981-18-6
Molecular Formula:
C14H18N4O2
Molecular Weight:
274.3183
MDL Number:
MFCD00057747
SMILES:
COc1cc(Cc2cnc(nc2N)N)c(cc1OC)C
NSC Number:
95072
Properties
Computed Properties
 
Complexity:
305  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
1.2  

Downstream Synthesis Route

[1]Manchand,PercyS.;Rosen,Perry;Belica,PeterS.;Oliva,GloriaV.;Perrotta,AgostinoV.;Wong,HarryS.[JournalofOrganicChemistry,1992,vol.57,#13,p.3531-3535]

[1]Manchand,PercyS.;Rosen,Perry;Belica,PeterS.;Oliva,GloriaV.;Perrotta,AgostinoV.;Wong,HarryS.[JournalofOrganicChemistry,1992,vol.57,#13,p.3531-3535]

[1]Manchand,PercyS.;Rosen,Perry;Belica,PeterS.;Oliva,GloriaV.;Perrotta,AgostinoV.;Wong,HarryS.[JournalofOrganicChemistry,1992,vol.57,#13,p.3531-3535]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-US4143227,1979,A

[1]Manchand,PercyS.;Rosen,Perry;Belica,PeterS.;Oliva,GloriaV.;Perrotta,AgostinoV.;Wong,HarryS.[JournalofOrganicChemistry,1992,vol.57,#13,p.3531-3535]

[2]CurrentPatentAssignee:HUBEILONGXIANGPHARMACEUTICALTECH-CN107311938,2017,A

[3]CurrentPatentAssignee:ZHENHAIVICTORPHARM-CN104803924,2017,B

Literature

Title: Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.

Journal: Bioorganic & medicinal chemistry letters 20090315

Title: Sorption of the veterinary antimicrobials sulfadimethoxine and ormetoprim in soil.

Journal: Journal of environmental quality 20080101

Title: Sulfadimethoxine and ormetoprim residues in three species of fish after oral dosing in feed.

Journal: Journal of aquatic animal health 20070601

Title: Simultaneous determination of 17 sulfonamides and the potentiators ormetoprim and trimethoprim in salmon muscle by liquid chromatography with tandem mass spectrometry detection.

Journal: Journal of AOAC International 20070101

Title: Observational study of hepatic cytochrome P-450 protein expression and activity in summer flounder (Paralichtys dentatus) after combination ormetoprim-sulfadimethoxine treatment.

Journal: Chemotherapy 20070101

Title: Epidemiologic cutoff values for antimicrobial agents against Aeromonas salmonicida isolates determined by frequency distributions of minimal inhibitory concentration and diameter of zone of inhibition data.

Journal: American journal of veterinary research 20061101

Title: Nephrotic syndrome associated with administration of sulfadimethoxine/ormetoprim in a dobermann.

Journal: The Journal of small animal practice 20050501

Title: Pharmacokinetics of sulfadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis).

Journal: Journal of veterinary pharmacology and therapeutics 20040201

Title: Acute columnaris infection in channel catfish, Ictalurus punctatus (Rafinesque): efficacy of practical treatments for warmwater aquaculture ponds.

Journal: Journal of fish diseases 20040101

Title: Comparison of ion-pairing and ion-suppressing liquid chromatographic methods for the determination of pyrimethamine and ormetoprim in chicken feed.

Journal: Journal of chromatographic science 20020701

Title: Sanders SM, et, al. Sorption of the veterinary antimicrobials sulfadimethoxine and ormetoprim in soil. J Environ Qual. 2008 Jun 23; 37(4): 1510-8.

Title: Guerard JJ, et, al. Photodegradation of ormetoprim in aquaculture and stream-derived dissolved organic matter. J Agric Food Chem. 2012 Oct 3; 60(39): 9801-6.

Title: Bakal RS, et, al. Pharmacokinetics of sulfadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis). J Vet Pharmacol Ther. 2004 Feb; 27(1): 1-6.

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Tags:6981-18-6 Molecular Formula|6981-18-6 MDL|6981-18-6 SMILES|6981-18-6 Ormetoprim