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Home Other Building Blocks 74711-43-6
74711-43-6,MFCD00864323
Catalog No.:AA00ICH4

74711-43-6 | Zaltoprofen

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$12.00   $8.00
- +
10g
97%
in stock  
$62.00   $43.00
- +
25g
97%
in stock  
$138.00   $96.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ICH4
Chemical Name:
Zaltoprofen
CAS Number:
74711-43-6
Molecular Formula:
C17H14O3S
Molecular Weight:
298.3563
MDL Number:
MFCD00864323
SMILES:
CC(C1=CC2=C(C=C1)SC3=CC=CC=C3C(=O)C2)C(=O)O
Properties
Computed Properties
 
Complexity:
422  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.5  

Downstream Synthesis Route
83237-49-4   
zaltoprofen 

[1]CurrentPatentAssignee:NIPPONCHEMIPHARCOLTD-EP2842952,2015,A1Locationinpatent:Paragraph0081;0082

[2]CurrentPatentAssignee:UBEINDUSTRIESLIMITED-US6111115,2000,A

[3]CurrentPatentAssignee:TIANJININSTITUTEOFPHARMACEUTICALRESEARCH-CN105218514,2016,ALocationinpatent:Paragraph0018;0019

[4]CurrentPatentAssignee:HENANHOUYIPHARMACY-CN110407804,2019,ALocationinpatent:Paragraph0010-0012

115441-83-3   
CASUnavailable 
  74711-43-6 

[1]CurrentPatentAssignee:NIPPONCHEMIPHARCOLTD-US4891433,1990,A

[2]CurrentPatentAssignee:NIPPONCHEMIPHARCOLTD-EP309626,1989,A1

[1]CurrentPatentAssignee:NIPPONCHEMIPHARCOLTD-US4891433,1990,A

[2]CurrentPatentAssignee:NIPPONCHEMIPHARCOLTD-US4891433,1990,A

[3]CurrentPatentAssignee:NIPPONCHEMIPHARCOLTD-US4891433,1990,A

[1]CurrentPatentAssignee:HEFEIJINKEBIOPHARMACEUTICALTECHNOLOGY-US2011/224276,2011,A1Locationinpatent:Page/Pagecolumn15

[1]CurrentPatentAssignee:HEFEIJINKEBIOPHARMACEUTICALTECHNOLOGY-US2011/224276,2011,A1Locationinpatent:Page/Pagecolumn15

Literature

Title: Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors.

Journal: Neuroscience research 20060401

Title: Preemptive analgesia by zaltoprofen that inhibits bradykinin action and cyclooxygenase in a post-operative pain model.

Journal: Neuroscience research 20050401

Title: Kawai S, et, al. Comparison of cyclooxygenase-1 and -2 inhibitory activities of various nonsteroidal anti-inflammatory drugs using human platelets and synovial cells. Eur J Pharmacol. 1998 Apr 17;347(1):87-94.

Title: Hirate K, et, al. Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors. Neurosci Res. 2006 Apr;54(4):288-94.

Title: Kameyama T, et, al. Analgesic and antiinflammatory effects of 2-(10,11-dihydro-10-oxo-dibenzo[b,fthiepin-2-yl)propionic acid in rat and mouse. Arzneimittelforschung. 1987 Jan;37(1):19-26.

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