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80154-34-3,MFCD00210992
Catalog No.:AA00ID0T

80154-34-3 | Helicid

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Purity
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1g
97%
in stock  
$19.00   $14.00
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5g
95%
in stock  
$56.00   $39.00
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10g
97%
in stock  
$66.00   $47.00
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25g
97%
in stock  
$123.00   $86.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ID0T
Chemical Name:
Helicid
CAS Number:
80154-34-3
Molecular Formula:
C13H16O7
Molecular Weight:
284.2619
MDL Number:
MFCD00210992
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)C=O)[C@@H]([C@@H]([C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
316  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
-0.9  

Downstream Synthesis Route

[1]Wei-shin,Chen;Shi-de,Lu;Breitmaier,Eberhard[LiebigsAnnalenderChemie,1981,#10,p.1893-1895]

[1]BioorganicandMedicinalChemistry,2009,vol.17,p.6937-6941

[1]Locationinpatent:experimentalpartWen,JunHe;Zhao,HuiFu;Hong,JinHan;He,Yan;Guang,ZhiZeng;Chang,JiuJi;Hong,BiaoChu;Yu,MeiZhang;Ning,HuaTan[ZeitschriftfurNaturforschung,B:ChemicalSciences,2011,vol.66,#7,p.733-739]

Literature

Title: Quantitative determination of helicid in rat biosamples by liquid chromatography electrospray ionization mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315

Title: Discovery of 4-functionalized phenyl-O-beta-D-glycosides as a new class of mushroom tyrosinase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20091101

Title: Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives.

Journal: Bioorganic & medicinal chemistry 20091001

Title: Synthesis and biological evaluation of helicid analogues as mushroom tyrosinase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20081215

Title: Quantitative determination of helicid in rat plasma by liquid chromatography-electrospray ionization mass spectrometry and its application to preliminary pharmacokinetic studies.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301

Title: Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives.

Journal: Bioorganic & medicinal chemistry letters 20060201

Title: [Study on chemical constituents in seeds of Helicia nilagirica (II)].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050601

Title: Tong J, et al. Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. Int Immunopharmacol. 2019 Feb;67:13-21.

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SDS
Tags:80154-34-3 Molecular Formula|80154-34-3 MDL|80154-34-3 SMILES|80154-34-3 Helicid