88889-14-9,MFCD00897699
Catalog No.:AA00IFFJ

88889-14-9 | Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate

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5mg
98%
in stock  
$6.00   $4.00
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10mg
98%
in stock  
$8.00   $6.00
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25mg
98%
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$11.00   $8.00
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50mg
98%
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00IFFJ
Chemical Name:
Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate
CAS Number:
88889-14-9
Molecular Formula:
C30H45NNaO7P
Molecular Weight:
585.6443
MDL Number:
MFCD00897699
SMILES:
CCC(=O)O[C@H](C(C)C)O[P@@](=O)(CC(=O)N1C[C@@H](C[C@H]1C(=O)[O-])C1CCCCC1)CCCCc1ccccc1.[Na+]
Properties
Computed Properties
 
Complexity:
857  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
15  
Undefined Atom Stereocenter Count:
2  

Literature

Title: Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.

Journal: Toxicology letters 20181001

Title: Mrp2 is involved in the efflux and disposition of fosinopril.

Journal: Journal of applied toxicology : JAT 20130601

Title: Visit-to-visit blood pressure variability is a strong predictor of cardiovascular events in hemodialysis: insights from FOSIDIAL.

Journal: Hypertension (Dallas, Tex. : 1979) 20120801

Title: [Effects of Xinjierkang on two kidney one clip-induced hypertension and target organ injury in rats].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20120401

Title: Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice.

Journal: Pharmacological research 20120301

Title: Intrarenal metabolomics reveals the association of local organic toxins with the progression of diabetic kidney disease.

Journal: Journal of pharmaceutical and biomedical analysis 20120223

Title: Effect of certain angiotensin-converting enzyme inhibitors on mortality in heart failure: a multiple-propensity analysis.

Journal: Research in social & administrative pharmacy : RSAP 20120101

Title: Angiotensin converting enzyme inhibitors mitigate collagen synthesis induced by a single dose of radiation to the whole thorax.

Journal: Journal of radiation research 20120101

Title: [Effect of Astragalus and Salvia's effective components and their compatibility on JAK/STAT pathway].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110901

Title: Fosinopril-cyclodextrin inclusion complexes: phase solubility and physicochemical analysis.

Journal: Die Pharmazie 20110801

Title: Meta-analysis of randomized controlled trials on effect of angiotensin-converting enzyme inhibitors on cancer risk.

Journal: The American journal of cardiology 20110715

Title: Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT).

Journal: American heart journal 20110601

Title: Effects of fosinopril and losartan on renal Klotho expression and oxidative stress in spontaneously hypertensive rats.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20110101

Title: Fosinopril and losartan regulate klotho gene and nicotinamide adenine dinucleotide phosphate oxidase expression in kidneys of spontaneously hypertensive rats.

Journal: Kidney & blood pressure research 20110101

Title: Fosinopril and valsartan intervention in gene expression of Klotho, MMP-9, TIMP-1, and PAI-1 in the kidney of spontaneously hypertensive rats.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20101001

Title: [Fosinopril up-regulates and ameliorates the Ang II induced down-expression of klotho gene in NRK-52E].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20100801

Title: [Protective effect of fosinopril sodium pretreatment combined with ischemic postconditioning on rat heart underwent myocardial ischemia/reperfusion injury].

Journal: Zhonghua xin xue guan bing za zhi 20100701

Title: Effects of ACE-inhibition on IGF-1 and IGFBP-3 concentrations in older adults with high cardiovascular risk profile.

Journal: The journal of nutrition, health & aging 20100601

Title: Effects of combination therapy with amlodipine and fosinopril administered at different times on blood pressure and circadian blood pressure pattern in patients with essential hypertension.

Journal: Acta cardiologica 20100601

Title: Prostaglandin E1 for preventing the progression of diabetic kidney disease.

Journal: The Cochrane database of systematic reviews 20100512

Title: Combination therapy with angiotensin-converting enzyme inhibitors and indapamide impairs glucose tolerance in Chinese hypertensive patients.

Journal: Blood pressure 20100401

Title: Effect of combined angiotensin-converting enzyme and aldosterone inhibition on plasma plasminogen activator inhibitor type 1 levels in chronic hypertensive patients.

Journal: Nephrology (Carlton, Vic.) 20100301

Title: ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

Journal: Journal of the American Medical Directors Association 20100101

Title: Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial.

Journal: BMJ (Clinical research ed.) 20100101

Title: [Antihypertensive effect of metformin in essential hypertensive patients with hyperinsulinemia.].

Journal: Zhonghua nei ke za zhi 20100101

Title: [Effects of Panax notoginseng saponins on ACE2 and TNF-alpha in rats with post-myocardial infarction-ventricular remodeling].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100101

Title: Primary gait ignition disorder: report of three cases.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20090801

Title: [Plasma tissue factor and serum angiotensin II and the therapeutic effect of different dosages of fosinopril on chronic heart failure].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090501

Title: [Efficacy of fosinopril on proteinuria in children with Henoch-Schonlein purpura nephritis].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20090301

Title: Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

Journal: American heart journal 20090201

Title: [Fosinopril in the treatment of cardiorenal syndrome in chronic cardiac failure].

Journal: Terapevticheskii arkhiv 20090101

Title: [The use of monopril in elderly patients with arterial hypertension and coronary heart disease].

Journal: Klinicheskaia meditsina 20090101

Title: Successful treatment of fosinopril-induced severe cholestatic jaundice with plasma exchange.

Journal: The Annals of pharmacotherapy 20081201

Title: Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.

Journal: The Journal of pharmacology and experimental therapeutics 20081101

Title: Spectrophotometric and atomic absorption determination of ramipril, enalapril maleate and fosinopril through ternary complex formation with molybdenum (V)-thiocyanate (Mo(V)-SCN).

Journal: Chemical & pharmaceutical bulletin 20081101

Title: Clinical variables, not RAAS polymorphisms, predict blood pressure response to ACE inhibitors in Sardinians.

Journal: Pharmacogenomics 20081001

Title: [Effects of fosinopril and losartan on the expression of Toll- like receptor 4 in renal tubular epithelia cells].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20081001

Title: Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20080901

Title: Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuria.

Journal: The American journal of cardiology 20080715

Title: Effects of a fixed-dose ACE inhibitor-diuretic combination on ambulatory blood pressure and arterial properties in isolated systolic hypertension.

Journal: Journal of cardiovascular pharmacology 20080601

Title: Specificity of MMP-9 assays.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20080601

Title: Monitoring of fosinopril sodium impurities by liquid chromatography-mass spectrometry including the neural networks in method evaluation.

Journal: Journal of chromatography. A 20080502

Title: Antidepressant activity of fosinopril, ramipril and losartan, but not of lisinopril in depressive paradigms of albino rats and mice.

Journal: Indian journal of experimental biology 20080301

Title: Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats.

Journal: Clinical and experimental pharmacology & physiology 20080201

Title: Microalbuminuria in type 2 diabetes and hypertension: a marker, treatment target, or innocent bystander?

Journal: Diabetes care 20080201

Title: Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects.

Journal: Atherosclerosis 20080101

Title: Fosinopril prevents the pulmonary arterial remodeling in sinoaortic-denervated rats by regulating phosphodiesterase.

Journal: Journal of cardiovascular pharmacology 20080101

Title: [Clinical efficiency of the use of monopril, propanolol and heparinum in stationary rehabilitation of patients with myocardial infarction].

Journal: Klinicheskaia meditsina 20080101

Title: Predictors of cardiovascular events in patients with end-stage renal disease: an analysis from the Fosinopril in dialysis study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071201

Title: Plasma matrix metalloproteinase-9 and ACE-inhibitor-induced improvement of urinary albumin excretion in non-diabetic, microalbuminuric subjects.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20071201

Title: Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins.

Journal: Nephrology (Carlton, Vic.) 20071001

Title: [Nephrotoxicity of high- and low-osmolar contrast media: Protective role of fosinopril or telmisartan in a rat model].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20071001

Title: Development and validation of liquid chromatography-tandem mass spectrometric method for simultaneous determination of fosinopril and its active metabolite fosinoprilat in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070701

Title: Effects of angiotensin-converting enzyme inhibitors and beta-adrenergic blockers on retinal vascular endothelial growth factor expression in rat diabetic retinopathy.

Journal: Experimental eye research 20070401

Title: [Effects of fosinopril on proliferation and secretion of extracellular matrix of rat glomerular mesangial cell].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20070401

Title: Primary hyperaldosteronism in a patient with end-stage renal disease.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070301

Title: Chronic pretreatment of ACEI reduces no-reflow in patients with acute myocardial infarction treated with primary angioplasty.

Journal: Clinical cardiology 20070301

Title: Images in emergency medicine. Angioedema as a result of angiotensin-converting enzyme inhibitor.

Journal: Annals of emergency medicine 20070201

Title: Fosinopril H(2)-receptor antagonists interaction studies by derivative spectroscopy.

Journal: Pakistan journal of pharmaceutical sciences 20070101

Title: [Comparative evaluation of the influence of sulfhydryl and phosphate ACE inhibitors on thrombocyte aggregation in patients suffering from atrerial hypertension with metabolic syndrome].

Journal: Klinicheskaia meditsina 20070101

Title: [Fosinopril but not metoprolol attenuated the increased matrix metallo-proteinases 9 expression at mRNA and protein levels of human umbilical vein endothelial cells exposed to oscillatory flow].

Journal: Zhonghua xin xue guan bing za zhi 20061201

Title: Cardiac treatment in neuro-muscular diseases.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20061201

Title: [Evolution of the bone mass of hypertense menopausal women in treatment with fosinopril].

Journal: Medicina clinica 20061111

Title: Predictors of angiotensin-converting enzyme inhibitor-induced reduction of urinary albumin excretion in nondiabetic patients.

Journal: Hypertension (Dallas, Tex. : 1979) 20061101

Title: Prevention of cardiovascular events in end-stage renal disease: results of a randomized trial of fosinopril and implications for future studies.

Journal: Kidney international 20061001

Title: Clinical study on effect of Garlicin in stabilizing the carotid artery atherosclerotic plaque in patients with primary hypertension and coronary artery disease.

Journal: Chinese journal of integrative medicine 20060901

Title: Pretreatment with fosinopril or valsartan reduces myocardial no-reflow after acute myocardial infarction and reperfusion.

Journal: Coronary artery disease 20060801

Title: Racial differences are seen in blood pressure response to fosinopril in hypertensive children.

Journal: American heart journal 20060801

Title: Fosinopril and carvedilol reverse hypertrophy and change the levels of protein kinase C epsilon and components of its signaling complex.

Journal: Cardiovascular drugs and therapy 20060801

Title: Effect of fosinopril in children with steroid-resistant idiopathic nephrotic syndrome.

Journal: Pediatric nephrology (Berlin, Germany) 20060701

Title: Therapeutic conversion from fosinopril to benazepril at a Veterans Affairs medical center.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060601

Title: Captopril inhibits the oxidative modification of apolipoprotein B-100 caused by myeloperoxydase in a comparative in vitro assay of angiotensin converting enzyme inhibitors.

Journal: European journal of pharmacology 20060510

Title: The efficacy and tolerability of fosinopril in Chinese type 2 diabetic patients with moderate renal insufficiency.

Journal: Diabetes, obesity & metabolism 20060501

Title: Randomised controlled trial of leflunomide in the treatment of immunoglobulin A nephropathy.

Journal: Nephrology (Carlton, Vic.) 20060401

Title: Cost-effectiveness of screening for albuminuria with subsequent fosinopril treatment to prevent cardiovascular events: A pharmacoeconomic analysis linked to the prevention of renal and vascular endstage disease (PREVEND) study and the prevention of renal and vascular endstage disease intervention trial (PREVEND IT).

Journal: Clinical therapeutics 20060301

Title: Effects of blocking the renin-angiotensin system on expression and translocation of protein kinase C isoforms in the kidney of diabetic rats.

Journal: Nephron. Experimental nephrology 20060101

Title: [Hyperkalemia in hypertensive patients undergoing regular hemodialysis during enalapril and fosinopril therapy].

Journal: Srpski arhiv za celokupno lekarstvo 20060101

Title: [Evaluation of the effectivenes of treatment of patients with renal arterial hypertension with carvedilol].

Journal: Klinicheskaia meditsina 20060101

Title: [Effect of fosinopril on progression of the asymptomatic carotid atherosclerosis and left ventricular hypertrophy in hypertensive patients].

Journal: Srpski arhiv za celokupno lekarstvo 20060101

Title: [Head-to-head comparison of clinical, biochemical and functional effects of fosinopril and enalapril in patients with systolic heart failure].

Journal: Medicinski pregled 20060101

Title: Transient recurrent ascites.

Journal: Acta gastro-enterologica Belgica 20060101

Title: Microemulsion liquid chromatographic method for characterisation of fosinopril sodium and fosinoprilat separation with chemometrical support.

Journal: Analytical and bioanalytical chemistry 20051001

Title: Development of liquid chromatographic method for fosinoprilat determination in human plasma using microemulsion as eluent.

Journal: Journal of chromatography. A 20050923

Title: Impact of statins in microalbuminuric subjects with the metabolic syndrome: a substudy of the PREVEND Intervention Trial.

Journal: European heart journal 20050701

Title: [Beneficial effects of fosinopril on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion].

Journal: Zhonghua xin xue guan bing za zhi 20050701

Title: Expression and activation of STAT3 in chronic proliferative immune complex glomerulonephritis and the effect of fosinopril.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501

Title: [Effects of pravastatin, fosinopril and their combination on myocardium TNF-alpha expression and ventricular remodeling after myocardial infarction in rats].

Journal: Zhonghua xin xue guan bing za zhi 20050501

Title: [Effects of combination therapy with angiotensin I-converting enzyme inhibitor and angiotensin 1 receptor antagonist on ventricular remodeling and expression of endothelial nitric oxide synthase].

Journal: Zhonghua yi xue za zhi 20050420

Title: Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria.

Journal: Stroke 20050301

Title: Lithium toxicity after switch from fosinopril to lisinopril.

Journal: International clinical psychopharmacology 20050301

Title: Effects of amlodipine and fosinopril on heart rate variability and left ventricular mass in mild-to-moderate essential hypertension.

Journal: International journal of clinical practice 20050301

Title: Acute administration of angiotensin converting enzyme inhibitors in thrombolysed myocardial infarction patients is associated with a decreased incidence of heart failure, but an increased re-infarction risk.

Journal: Cardiovascular drugs and therapy 20050301

Title: [Applicability of fozinopril for correction of basic manifestations of metabolic syndrome in women with arterial hypertension].

Journal: Terapevticheskii arkhiv 20050101

Title: [Effects of ACE inhibitor fosinopril on a 24-h profile of arterial pressure in hypertensive patients with obesity and hypercholesterolemia].

Journal: Terapevticheskii arkhiv 20050101

Title: For potential resolution of cough associated with an angiotensin-converting enzyme inhibitor.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20050101

Title: [Implantation of an extracardiac mesh in the treatment of dilated cardiomyopathy: the TOLK Study (Therapevticheskoe Operativnoe Lechenie Kardiomyopatye)].

Journal: Kardiologiia 20050101

Title: Synthesis of optically active trans 4-cyclohexyl-L-proline as an intermediate product in the preparation of fosinopril.

Journal: Acta poloniae pharmaceutica 20050101

Title: [Microalbuminuria--an independent indication for administration of ACE inhibitors: role of fosinopril (PREVEND IT trial)].

Journal: Terapevticheskii arkhiv 20050101

Title: [Hypertension combined with atherosclerotic lesions in carotid arteries: should angiotensin converting enzyme inhibitors be prescribed?].

Journal: Kardiologiia 20050101

Title: [Effect of fosinopril on some parameters of endothelial function in patients with metabolic syndrome].

Journal: Kardiologiia 20050101

Title: [Changes of collagen expression of pulmonary arteries and heart ventricles and intervention of fosinopril and losartan in rats with heart failure].

Journal: Zhonghua yi xue za zhi 20041202

Title: Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial.

Journal: Stroke 20041201

Title: Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria.

Journal: Circulation 20041102

Title: Is the extrapolated adult dose of fosinopril safe and effective in treating hypertensive children?

Journal: Hypertension (Dallas, Tex. : 1979) 20040901

Title: Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports).

Journal: Diabetes research and clinical practice 20040901

Title: Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.

Journal: Pharmacological research 20040801

Title: Clinical trials update from the European Society of Cardiology Heart Failure meeting: SHAPE, BRING-UP 2 VAS, COLA II, FOSIDIAL, BETACAR, CASINO and meta-analysis of cardiac resynchronisation therapy.

Journal: European journal of heart failure 20040801

Title: Comparative effects of fosinopril and irbesartan on hematopoiesis in essential hypertensives.

Journal: Renal failure 20040701

Title: Normalization of renal aquaporin-2 water channel expression by fosinopril, valsartan, and combination therapy in congestive heart failure: a new mechanism of action.

Journal: Journal of molecular and cellular cardiology 20040301

Title: Cardiorenal protective effects of vasopeptidase inhibition with omapatrilat in hypertensive transgenic (mREN-2)27 rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20040101

Title: Role of Angiotensin-converting enzyme and neutral endopeptidase in flow-dependent remodeling.

Journal: Journal of vascular research 20040101

Title: Systemic contact dermatitis due to captopril without cross-sensitivity to fosinopril, quinapril and benazepril.

Journal: Acta dermato-venereologica 20040101

Title: Fosinopril and amlodipine in the treatment of isolated systolic hypertension.

Journal: Medicinski pregled 20040101

Title: A unique form of polycythemia associated with minimal change disease.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20040101

Title: [Effect of fosinopril on the rate of neurohumoral and proinflammatory activation in patients with heart failure].

Journal: Klinicheskaia meditsina 20040101

Title: Ramipril-associated hepatotoxicity.

Journal: Archives of pathology & laboratory medicine 20031101

Title: Angiotensin-converting enzyme inhibition but not angiotensin II receptor blockade regulates matrix metalloproteinase activity in patients with glomerulonephritis.

Journal: Journal of the American Society of Nephrology : JASN 20031101

Title: Effect of dual angiotensin converting enzyme/neutral endopeptidase inhibition, angiotensin converting enzyme inhibition, or AT1 antagonism on coronary microvasculature in spontaneously hypertensive rats.

Journal: American journal of hypertension 20031101

Title: Long-term renal survival in HIV-associated nephropathy with angiotensin-converting enzyme inhibition.

Journal: Kidney international 20031001

Title: Dual renin-angiotensin system blockade restores blood pressure-renin dependency in individuals with low renin concentrations.

Journal: Journal of hypertension 20031001

Title: Introduction to monitoring. What is what you prescribed actually doing?

Journal: Australian family physician 20031001

Title: Protection of organic trauma in sinoaortic-denervated rats treated with fosinopril.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20031001

Title: Comparative metabolic effects of hydrochlorothiazide and indapamide in hypertensive diabetic patients receiving ACE inhibitor therapy.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20030901

Title: [Combination therapy with losartan and fosinopril for early diabetic nephropathy].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030901

Title: Acute visual loss after initiation of antihypertensive therapy: case report.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030819

Title: Effects of fosinopril and valsartan on expressions of ICAM-1 and NO in human umbilical vein endothelial cells.

Journal: Chinese medical journal 20030601

Title: ANP but not BNP reflects early left diastolic dysfunction in type 1 diabetics with myocardial dysinnervation.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030501

Title: Comparison of dipyridamole and fosinopril on renal progression in nephrectomized rats.

Journal: Nephrology (Carlton, Vic.) 20030401

Title: A prospective, randomized, open labeled crossover trial of fosinopril and theophylline in post renal transplant erythrocytosis.

Journal: Renal failure 20030101

Title: [Chronopharmacological approaches to the therapeutic prophylaxis of chronic cardiac insufficiency in type I diabetes mellitus].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20030101

Title: [Tongue angioedema associated with angiotensin-converting enzyme inhibitor (diagnosis, differential diagnosis, treatment)].

Journal: Medicina (Kaunas, Lithuania) 20030101

Title: [Efficacy of combined use of fosinopril and propranolol in acute myocardial infarction].

Journal: Kardiologiia 20030101

Title: Precipitation of PTSD with metoprolol for hypertension.

Journal: Psychosomatics 20030101

Title: Effects of amlodipine fosinopril combination on microalbuminuria in hypertensive type 2 diabetic patients.

Journal: American journal of hypertension 20021201

Title: Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.

Journal: Hypertension (Dallas, Tex. : 1979) 20021201

Title: Regression of ventricular and vascular hypertrophy: are there differences between structurally different angiotensin-converting enzyme inhibitors?

Journal: Journal of hypertension 20021201

Title: [Comparison of the antihypertensive activity of fosinopril and irbesartan].

Journal: Anales de medicina interna (Madrid, Spain : 1984) 20021101

Title: The effects of losartan and fosinopril in hypertensive type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20021001

Title: Physiologic consequences of vasopeptidase inhibition in humans: effect of sodium intake.

Journal: Journal of the American Society of Nephrology : JASN 20021001

Title: Hemodynamic and humoral effects of vasopeptidase inhibition in canine hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20021001

Title: FOSIDIAL: a randomised placebo controlled trial of the effects of fosinopril on cardiovascular morbidity and mortality in haemodialysis patients. Study design and patients' baseline characteristics.

Journal: Fundamental & clinical pharmacology 20021001

Title: Apoptosis, myocardial fibrosis and angiotensin II in the left ventricle of hypertensive rats treated with fosinopril or losartan.

Journal: Chinese medical journal 20020901

Title: Using ACE inhibitors appropriately.

Journal: American family physician 20020801

Title: Safe drug prescribing.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020625

Title: Fosinopril-induced hepatotoxicity in a complex medical patient.

Journal: Tennessee medicine : journal of the Tennessee Medical Association 20020401

Title: Simultaneous determination of fosinopril and hydrochlorothiazide in pharmaceutical formulations by spectrophotometric methods.

Journal: Journal of pharmaceutical and biomedical analysis 20020301

Title: Fosinopril improves left ventricular diastolic function in young mildly hypertensive patients without hypertrophy.

Journal: Cardiovascular drugs and therapy 20020301

Title: Fosinopril versus amlodipine comparative treatments study: a randomized trial to assess effects on plasminogen activator inhibitor-1.

Journal: Circulation 20020129

Title: Additive antiproteinuric effect of combined ACE inhibition and angiotensin II receptor blockade.

Journal: Journal of hypertension 20020101

Title: Fosinopril as a possible pemphigus-inducing drug.

Journal: Dermatology (Basel, Switzerland) 20020101

Title: Fixed combinations of delapril plus indapamide vs fosinopril plus hydrochlorothiazide in mild to moderate essential hypertension.

Journal: Advances in therapy 20020101

Title: [Renoprotective effect of monopril in patients with diabetes mellitus in the preclinical stage of diabetic nephropathy].

Journal: Likars'ka sprava 20020101

Title: [Changes of distensibility of the aorta in elderly patients during long-term therapy with various classes of hypotensive drugs (magnetic resonance tomography data)].

Journal: Kardiologiia 20020101

Title: [FLAG--a program of achievability of target blood pressure levels during treatment of patients with hypertension with fosinopril].

Journal: Kardiologiia 20020101

Title: The effect and mechanism of forsinopril on ventricular hypertrophy of SHR and left ventricular pressure overloading rat.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101

Title: The cardiovascular actions of omapatrilat in spontaneously hypertensive rats.

Journal: Current hypertension reports 20011201

Title: Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats.

Journal: International journal of cardiology 20011201

Title: ACE inhibitor-induced angioedema of the intestine: Case report, incidence, pathophysiology, diagnosis and management.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20011201

Title: [Effectiveness and tolerance of fosinopril in the treatment of arterial hypertension of mild and medium severity].

Journal: Vnitrni lekarstvi 20011201

Title: [Contrast of losartan, fosinopril and amlodipine on cardiomyocyte apoptosis and left ventricular remolding in hypertensive rats].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20011028

Title: Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20011001

Title: Effects of combination of angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarction.

Journal: Journal of the American College of Cardiology 20011001

Title: Angiotensin converting enzyme inhibition improves cardiac neuronal uptake of noradrenaline in spontaneously hypertensive rats.

Journal: Journal of hypertension 20011001

Title: A random comparison of fosinopril and nifedipine GITS in patients with primary renal disease.

Journal: Journal of hypertension 20011001

Title: Angiotensin-converting enzyme inhibition induces apoptosis in erythroid precursors and affects insulin-like growth factor-1 in posttransplantation erythrocytosis.

Journal: Journal of the American Society of Nephrology : JASN 20010901

Title: Vasopeptidase inhibition attenuates the progression of renal injury in subtotal nephrectomized rats.

Journal: Kidney international 20010801

Title: Endogenous natriuretic peptides participate in renal and humoral actions of acute vasopeptidase inhibition in experimental mild heart failure.

Journal: Hypertension (Dallas, Tex. : 1979) 20010801

Title: Hepatotoxicity induced by fosinopril.

Journal: Journal of hepatology 20010801

Title: The effects of ACE inhibitor therapy on left ventricular myocardial mass and diastolic filling in previously untreated hypertensive patients: a cine MRI study.

Journal: Journal of magnetic resonance imaging : JMRI 20010701

Title: Effects of fosinopril on renal function, baroreflex response and noradrenaline pressor response in conscious normotensive dogs.

Journal: Veterinary research communications 20010701

Title: [Effects of lorsartan, fosinopril on myocardial fibrosis, angiotensin II and cardiac remolding in hypertensive rats].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University 20010428

Title: Fosinopril-induced prolonged cholestatic jaundice and pruritus: first case report.

Journal: European journal of gastroenterology & hepatology 20010301

Title: Comparison of the first dose response of fosinopril and captopril in congestive heart failure: a randomized, double-blind, placebo controlled study.

Journal: Japanese heart journal 20010301

Title: Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lowering Italian Study. PHYLLIS study group.

Journal: Journal of hypertension 20010101

Title: Effects of omapatrilat on blood pressure and insulin sensitivity in an animal model of insulin resistance.

Journal: Blood pressure 20010101

Title: Effects of spironolactone and fosinopril on the spontaneous and chronic ventricular arrhythmias in a rat model of myocardial infarction.

Journal: Cardiology 20010101

Title: Cocaine, HIV, and their cardiovascular effects: is there a role for ACE-inhibitor therapy?

Journal: Drug and alcohol dependence 20001222

Title: Effect of valsartan and fosinopril on catecholamine-induced cardiac hypertrophy.

Journal: Acta pharmacologica Sinica 20000901

Title: The hemodynamic effects of long-term ACE inhibition with fosinopril in patients with heart failure. Fosinopril Hemodynamics Study Group.

Journal: American journal of therapeutics 19990701

Title: Elevation of serum creatinine following fosinopril therapy.

Journal: The Annals of pharmacotherapy 19990301

Title: New evidence on the prevention of cardiovascular events in hypertensive patients with type 2 diabetes.

Journal: Journal of cardiovascular pharmacology 19980101

Title: Effects of atenolol as add-on therapy to fosinopril in heart failure.

Journal: Wiener klinische Wochenschrift 19970411

Title: Albuminuria and transferrinuria in essential hypertension. Effects of antihypertensive therapy.

Journal: American journal of hypertension 19961101

Title: [Evaluation of the total hepatic function after treatment with fosinopril in hypertensive patients with liver cirrhosis].

Journal: La Clinica terapeutica 19941201

Title: Disparate cardiovascular response to stress tests during isradipine and fosinopril therapy.

Journal: The American journal of cardiology 19930901

Title: Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology.

Journal: Journal of cardiovascular pharmacology 19891101

Title: Ondetti, M.A., Structural relationships of angiotensin converting-enzyme inhibitors to pharmacologic activity. Circulation, 1988. 77(6 Pt 2): p. I74-8.

Title: Piepho, R.W., Overview of the angiotensin-converting-enzyme inhibitors. Am J Health Syst Pharm, 2000. 57 Suppl 1: p. S3-7.

Title: Sharma, S., et al., The hemodynamic effects of long-term ACE inhibition with fosinopril in patients with heart failure. Fosinopril Hemodynamics Study Group. Am J Ther, 1999. 6(4): p. 181-9.

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Tags:88889-14-9 Molecular Formula|88889-14-9 MDL|88889-14-9 SMILES|88889-14-9 Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate
Catalog No.: AA00IFFJ
88889-14-9,MFCD00897699
88889-14-9 | Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate
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Purity: 98%
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Technical Information
Catalog Number: AA00IFFJ
Chemical Name: Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate
CAS Number: 88889-14-9
Molecular Formula: C30H45NNaO7P
Molecular Weight: 585.6443
MDL Number: MFCD00897699
SMILES: CCC(=O)O[C@H](C(C)C)O[P@@](=O)(CC(=O)N1C[C@@H](C[C@H]1C(=O)[O-])C1CCCCC1)CCCCc1ccccc1.[Na+]
Properties
Complexity: 857  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 2  
Heavy Atom Count: 40  
Hydrogen Bond Acceptor Count: 7  
Rotatable Bond Count: 15  
Undefined Atom Stereocenter Count: 2  
Literature fold

Title: Perindopril, fosinopril and losartan inhibited the progression of diethylnitrosamine-induced hepatocellular carcinoma in mice via the inactivation of nuclear transcription factor kappa-B.

Journal: Toxicology letters20181001

Title: Mrp2 is involved in the efflux and disposition of fosinopril.

Journal: Journal of applied toxicology : JAT20130601

Title: Visit-to-visit blood pressure variability is a strong predictor of cardiovascular events in hemodialysis: insights from FOSIDIAL.

Journal: Hypertension (Dallas, Tex. : 1979)20120801

Title: [Effects of Xinjierkang on two kidney one clip-induced hypertension and target organ injury in rats].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20120401

Title: Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice.

Journal: Pharmacological research20120301

Title: Intrarenal metabolomics reveals the association of local organic toxins with the progression of diabetic kidney disease.

Journal: Journal of pharmaceutical and biomedical analysis20120223

Title: Effect of certain angiotensin-converting enzyme inhibitors on mortality in heart failure: a multiple-propensity analysis.

Journal: Research in social & administrative pharmacy : RSAP20120101

Title: Angiotensin converting enzyme inhibitors mitigate collagen synthesis induced by a single dose of radiation to the whole thorax.

Journal: Journal of radiation research20120101

Title: [Effect of Astragalus and Salvia's effective components and their compatibility on JAK/STAT pathway].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20110901

Title: Fosinopril-cyclodextrin inclusion complexes: phase solubility and physicochemical analysis.

Journal: Die Pharmazie20110801

Title: Meta-analysis of randomized controlled trials on effect of angiotensin-converting enzyme inhibitors on cancer risk.

Journal: The American journal of cardiology20110715

Title: Long-term effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria:Ten years of follow-up of Prevention of Renal and Vascular End-stage Disease Intervention Trial (PREVEND IT).

Journal: American heart journal20110601

Title: Effects of fosinopril and losartan on renal Klotho expression and oxidative stress in spontaneously hypertensive rats.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20110101

Title: Fosinopril and losartan regulate klotho gene and nicotinamide adenine dinucleotide phosphate oxidase expression in kidneys of spontaneously hypertensive rats.

Journal: Kidney & blood pressure research20110101

Title: Fosinopril and valsartan intervention in gene expression of Klotho, MMP-9, TIMP-1, and PAI-1 in the kidney of spontaneously hypertensive rats.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20101001

Title: [Fosinopril up-regulates and ameliorates the Ang II induced down-expression of klotho gene in NRK-52E].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology20100801

Title: [Protective effect of fosinopril sodium pretreatment combined with ischemic postconditioning on rat heart underwent myocardial ischemia/reperfusion injury].

Journal: Zhonghua xin xue guan bing za zhi20100701

Title: Effects of ACE-inhibition on IGF-1 and IGFBP-3 concentrations in older adults with high cardiovascular risk profile.

Journal: The journal of nutrition, health & aging20100601

Title: Effects of combination therapy with amlodipine and fosinopril administered at different times on blood pressure and circadian blood pressure pattern in patients with essential hypertension.

Journal: Acta cardiologica20100601

Title: Prostaglandin E1 for preventing the progression of diabetic kidney disease.

Journal: The Cochrane database of systematic reviews20100512

Title: Combination therapy with angiotensin-converting enzyme inhibitors and indapamide impairs glucose tolerance in Chinese hypertensive patients.

Journal: Blood pressure20100401

Title: Effect of combined angiotensin-converting enzyme and aldosterone inhibition on plasma plasminogen activator inhibitor type 1 levels in chronic hypertensive patients.

Journal: Nephrology (Carlton, Vic.)20100301

Title: ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

Journal: Journal of the American Medical Directors Association20100101

Title: Statins, antihypertensive treatment, and blood pressure control in clinic and over 24 hours: evidence from PHYLLIS randomised double blind trial.

Journal: BMJ (Clinical research ed.)20100101

Title: [Antihypertensive effect of metformin in essential hypertensive patients with hyperinsulinemia.].

Journal: Zhonghua nei ke za zhi20100101

Title: [Effects of Panax notoginseng saponins on ACE2 and TNF-alpha in rats with post-myocardial infarction-ventricular remodeling].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials20100101

Title: Primary gait ignition disorder: report of three cases.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology20090801

Title: [Plasma tissue factor and serum angiotensin II and the therapeutic effect of different dosages of fosinopril on chronic heart failure].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20090501

Title: [Efficacy of fosinopril on proteinuria in children with Henoch-Schonlein purpura nephritis].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics20090301

Title: Angiotensin-converting enzyme inhibition and novel cardiovascular risk biomarkers: results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study.

Journal: American heart journal20090201

Title: [Fosinopril in the treatment of cardiorenal syndrome in chronic cardiac failure].

Journal: Terapevticheskii arkhiv20090101

Title: [The use of monopril in elderly patients with arterial hypertension and coronary heart disease].

Journal: Klinicheskaia meditsina20090101

Title: Successful treatment of fosinopril-induced severe cholestatic jaundice with plasma exchange.

Journal: The Annals of pharmacotherapy20081201

Title: Transport of angiotensin-converting enzyme inhibitors by H+/peptide transporters revisited.

Journal: The Journal of pharmacology and experimental therapeutics20081101

Title: Spectrophotometric and atomic absorption determination of ramipril, enalapril maleate and fosinopril through ternary complex formation with molybdenum (V)-thiocyanate (Mo(V)-SCN).

Journal: Chemical & pharmaceutical bulletin20081101

Title: Clinical variables, not RAAS polymorphisms, predict blood pressure response to ACE inhibitors in Sardinians.

Journal: Pharmacogenomics20081001

Title: [Effects of fosinopril and losartan on the expression of Toll- like receptor 4 in renal tubular epithelia cells].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20081001

Title: Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20080901

Title: Effect of fosinopril treatment on serum C-reactive protein levels in patients with microalbuminuria.

Journal: The American journal of cardiology20080715

Title: Effects of a fixed-dose ACE inhibitor-diuretic combination on ambulatory blood pressure and arterial properties in isolated systolic hypertension.

Journal: Journal of cardiovascular pharmacology20080601

Title: Specificity of MMP-9 assays.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS20080601

Title: Monitoring of fosinopril sodium impurities by liquid chromatography-mass spectrometry including the neural networks in method evaluation.

Journal: Journal of chromatography. A20080502

Title: Antidepressant activity of fosinopril, ramipril and losartan, but not of lisinopril in depressive paradigms of albino rats and mice.

Journal: Indian journal of experimental biology20080301

Title: Inhibition of the renin-angiotensin system attenuates the development of liver fibrosis and oxidative stress in rats.

Journal: Clinical and experimental pharmacology & physiology20080201

Title: Microalbuminuria in type 2 diabetes and hypertension: a marker, treatment target, or innocent bystander?

Journal: Diabetes care20080201

Title: Long-term effects of pravastatin and fosinopril on peripheral endothelial function in albuminuric subjects.

Journal: Atherosclerosis20080101

Title: Fosinopril prevents the pulmonary arterial remodeling in sinoaortic-denervated rats by regulating phosphodiesterase.

Journal: Journal of cardiovascular pharmacology20080101

Title: [Clinical efficiency of the use of monopril, propanolol and heparinum in stationary rehabilitation of patients with myocardial infarction].

Journal: Klinicheskaia meditsina20080101

Title: Predictors of cardiovascular events in patients with end-stage renal disease: an analysis from the Fosinopril in dialysis study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20071201

Title: Plasma matrix metalloproteinase-9 and ACE-inhibitor-induced improvement of urinary albumin excretion in non-diabetic, microalbuminuric subjects.

Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS20071201

Title: Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins.

Journal: Nephrology (Carlton, Vic.)20071001

Title: [Nephrotoxicity of high- and low-osmolar contrast media: Protective role of fosinopril or telmisartan in a rat model].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20071001

Title: Development and validation of liquid chromatography-tandem mass spectrometric method for simultaneous determination of fosinopril and its active metabolite fosinoprilat in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20070701

Title: Effects of angiotensin-converting enzyme inhibitors and beta-adrenergic blockers on retinal vascular endothelial growth factor expression in rat diabetic retinopathy.

Journal: Experimental eye research20070401

Title: [Effects of fosinopril on proliferation and secretion of extracellular matrix of rat glomerular mesangial cell].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics20070401

Title: Primary hyperaldosteronism in a patient with end-stage renal disease.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20070301

Title: Chronic pretreatment of ACEI reduces no-reflow in patients with acute myocardial infarction treated with primary angioplasty.

Journal: Clinical cardiology20070301

Title: Images in emergency medicine. Angioedema as a result of angiotensin-converting enzyme inhibitor.

Journal: Annals of emergency medicine20070201

Title: Fosinopril H(2)-receptor antagonists interaction studies by derivative spectroscopy.

Journal: Pakistan journal of pharmaceutical sciences20070101

Title: [Comparative evaluation of the influence of sulfhydryl and phosphate ACE inhibitors on thrombocyte aggregation in patients suffering from atrerial hypertension with metabolic syndrome].

Journal: Klinicheskaia meditsina20070101

Title: [Fosinopril but not metoprolol attenuated the increased matrix metallo-proteinases 9 expression at mRNA and protein levels of human umbilical vein endothelial cells exposed to oscillatory flow].

Journal: Zhonghua xin xue guan bing za zhi20061201

Title: Cardiac treatment in neuro-muscular diseases.

Journal: Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology20061201

Title: [Evolution of the bone mass of hypertense menopausal women in treatment with fosinopril].

Journal: Medicina clinica20061111

Title: Predictors of angiotensin-converting enzyme inhibitor-induced reduction of urinary albumin excretion in nondiabetic patients.

Journal: Hypertension (Dallas, Tex. : 1979)20061101

Title: Prevention of cardiovascular events in end-stage renal disease: results of a randomized trial of fosinopril and implications for future studies.

Journal: Kidney international20061001

Title: Clinical study on effect of Garlicin in stabilizing the carotid artery atherosclerotic plaque in patients with primary hypertension and coronary artery disease.

Journal: Chinese journal of integrative medicine20060901

Title: Pretreatment with fosinopril or valsartan reduces myocardial no-reflow after acute myocardial infarction and reperfusion.

Journal: Coronary artery disease20060801

Title: Racial differences are seen in blood pressure response to fosinopril in hypertensive children.

Journal: American heart journal20060801

Title: Fosinopril and carvedilol reverse hypertrophy and change the levels of protein kinase C epsilon and components of its signaling complex.

Journal: Cardiovascular drugs and therapy20060801

Title: Effect of fosinopril in children with steroid-resistant idiopathic nephrotic syndrome.

Journal: Pediatric nephrology (Berlin, Germany)20060701

Title: Therapeutic conversion from fosinopril to benazepril at a Veterans Affairs medical center.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20060601

Title: Captopril inhibits the oxidative modification of apolipoprotein B-100 caused by myeloperoxydase in a comparative in vitro assay of angiotensin converting enzyme inhibitors.

Journal: European journal of pharmacology20060510

Title: The efficacy and tolerability of fosinopril in Chinese type 2 diabetic patients with moderate renal insufficiency.

Journal: Diabetes, obesity & metabolism20060501

Title: Randomised controlled trial of leflunomide in the treatment of immunoglobulin A nephropathy.

Journal: Nephrology (Carlton, Vic.)20060401

Title: Cost-effectiveness of screening for albuminuria with subsequent fosinopril treatment to prevent cardiovascular events: A pharmacoeconomic analysis linked to the prevention of renal and vascular endstage disease (PREVEND) study and the prevention of renal and vascular endstage disease intervention trial (PREVEND IT).

Journal: Clinical therapeutics20060301

Title: Effects of blocking the renin-angiotensin system on expression and translocation of protein kinase C isoforms in the kidney of diabetic rats.

Journal: Nephron. Experimental nephrology20060101

Title: [Hyperkalemia in hypertensive patients undergoing regular hemodialysis during enalapril and fosinopril therapy].

Journal: Srpski arhiv za celokupno lekarstvo20060101

Title: [Evaluation of the effectivenes of treatment of patients with renal arterial hypertension with carvedilol].

Journal: Klinicheskaia meditsina20060101

Title: [Effect of fosinopril on progression of the asymptomatic carotid atherosclerosis and left ventricular hypertrophy in hypertensive patients].

Journal: Srpski arhiv za celokupno lekarstvo20060101

Title: [Head-to-head comparison of clinical, biochemical and functional effects of fosinopril and enalapril in patients with systolic heart failure].

Journal: Medicinski pregled20060101

Title: Transient recurrent ascites.

Journal: Acta gastro-enterologica Belgica20060101

Title: Microemulsion liquid chromatographic method for characterisation of fosinopril sodium and fosinoprilat separation with chemometrical support.

Journal: Analytical and bioanalytical chemistry20051001

Title: Development of liquid chromatographic method for fosinoprilat determination in human plasma using microemulsion as eluent.

Journal: Journal of chromatography. A20050923

Title: Impact of statins in microalbuminuric subjects with the metabolic syndrome: a substudy of the PREVEND Intervention Trial.

Journal: European heart journal20050701

Title: [Beneficial effects of fosinopril on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion].

Journal: Zhonghua xin xue guan bing za zhi20050701

Title: Expression and activation of STAT3 in chronic proliferative immune complex glomerulonephritis and the effect of fosinopril.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20050501

Title: [Effects of pravastatin, fosinopril and their combination on myocardium TNF-alpha expression and ventricular remodeling after myocardial infarction in rats].

Journal: Zhonghua xin xue guan bing za zhi20050501

Title: [Effects of combination therapy with angiotensin I-converting enzyme inhibitor and angiotensin 1 receptor antagonist on ventricular remodeling and expression of endothelial nitric oxide synthase].

Journal: Zhonghua yi xue za zhi20050420

Title: Effects of fosinopril and pravastatin on carotid intima-media thickness in subjects with increased albuminuria.

Journal: Stroke20050301

Title: Lithium toxicity after switch from fosinopril to lisinopril.

Journal: International clinical psychopharmacology20050301

Title: Effects of amlodipine and fosinopril on heart rate variability and left ventricular mass in mild-to-moderate essential hypertension.

Journal: International journal of clinical practice20050301

Title: Acute administration of angiotensin converting enzyme inhibitors in thrombolysed myocardial infarction patients is associated with a decreased incidence of heart failure, but an increased re-infarction risk.

Journal: Cardiovascular drugs and therapy20050301

Title: [Applicability of fozinopril for correction of basic manifestations of metabolic syndrome in women with arterial hypertension].

Journal: Terapevticheskii arkhiv20050101

Title: [Effects of ACE inhibitor fosinopril on a 24-h profile of arterial pressure in hypertensive patients with obesity and hypercholesterolemia].

Journal: Terapevticheskii arkhiv20050101

Title: For potential resolution of cough associated with an angiotensin-converting enzyme inhibitor.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists20050101

Title: [Implantation of an extracardiac mesh in the treatment of dilated cardiomyopathy: the TOLK Study (Therapevticheskoe Operativnoe Lechenie Kardiomyopatye)].

Journal: Kardiologiia20050101

Title: Synthesis of optically active trans 4-cyclohexyl-L-proline as an intermediate product in the preparation of fosinopril.

Journal: Acta poloniae pharmaceutica20050101

Title: [Microalbuminuria--an independent indication for administration of ACE inhibitors: role of fosinopril (PREVEND IT trial)].

Journal: Terapevticheskii arkhiv20050101

Title: [Hypertension combined with atherosclerotic lesions in carotid arteries: should angiotensin converting enzyme inhibitors be prescribed?].

Journal: Kardiologiia20050101

Title: [Effect of fosinopril on some parameters of endothelial function in patients with metabolic syndrome].

Journal: Kardiologiia20050101

Title: [Changes of collagen expression of pulmonary arteries and heart ventricles and intervention of fosinopril and losartan in rats with heart failure].

Journal: Zhonghua yi xue za zhi20041202

Title: Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial.

Journal: Stroke20041201

Title: Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria.

Journal: Circulation20041102

Title: Is the extrapolated adult dose of fosinopril safe and effective in treating hypertensive children?

Journal: Hypertension (Dallas, Tex. : 1979)20040901

Title: Possible induction of diabetes by treatment of hypertension with indapamide (with four case reports).

Journal: Diabetes research and clinical practice20040901

Title: Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.

Journal: Pharmacological research20040801

Title: Clinical trials update from the European Society of Cardiology Heart Failure meeting: SHAPE, BRING-UP 2 VAS, COLA II, FOSIDIAL, BETACAR, CASINO and meta-analysis of cardiac resynchronisation therapy.

Journal: European journal of heart failure20040801

Title: Comparative effects of fosinopril and irbesartan on hematopoiesis in essential hypertensives.

Journal: Renal failure20040701

Title: Normalization of renal aquaporin-2 water channel expression by fosinopril, valsartan, and combination therapy in congestive heart failure: a new mechanism of action.

Journal: Journal of molecular and cellular cardiology20040301

Title: Cardiorenal protective effects of vasopeptidase inhibition with omapatrilat in hypertensive transgenic (mREN-2)27 rats.

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993)20040101

Title: Role of Angiotensin-converting enzyme and neutral endopeptidase in flow-dependent remodeling.

Journal: Journal of vascular research20040101

Title: Systemic contact dermatitis due to captopril without cross-sensitivity to fosinopril, quinapril and benazepril.

Journal: Acta dermato-venereologica20040101

Title: Fosinopril and amlodipine in the treatment of isolated systolic hypertension.

Journal: Medicinski pregled20040101

Title: A unique form of polycythemia associated with minimal change disease.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre20040101

Title: [Effect of fosinopril on the rate of neurohumoral and proinflammatory activation in patients with heart failure].

Journal: Klinicheskaia meditsina20040101

Title: Ramipril-associated hepatotoxicity.

Journal: Archives of pathology & laboratory medicine20031101

Title: Angiotensin-converting enzyme inhibition but not angiotensin II receptor blockade regulates matrix metalloproteinase activity in patients with glomerulonephritis.

Journal: Journal of the American Society of Nephrology : JASN20031101

Title: Effect of dual angiotensin converting enzyme/neutral endopeptidase inhibition, angiotensin converting enzyme inhibition, or AT1 antagonism on coronary microvasculature in spontaneously hypertensive rats.

Journal: American journal of hypertension20031101

Title: Long-term renal survival in HIV-associated nephropathy with angiotensin-converting enzyme inhibition.

Journal: Kidney international20031001

Title: Dual renin-angiotensin system blockade restores blood pressure-renin dependency in individuals with low renin concentrations.

Journal: Journal of hypertension20031001

Title: Introduction to monitoring. What is what you prescribed actually doing?

Journal: Australian family physician20031001

Title: Protection of organic trauma in sinoaortic-denervated rats treated with fosinopril.

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20031001

Title: Comparative metabolic effects of hydrochlorothiazide and indapamide in hypertensive diabetic patients receiving ACE inhibitor therapy.

Journal: Diabetic medicine : a journal of the British Diabetic Association20030901

Title: [Combination therapy with losartan and fosinopril for early diabetic nephropathy].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA20030901

Title: Acute visual loss after initiation of antihypertensive therapy: case report.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne20030819

Title: Effects of fosinopril and valsartan on expressions of ICAM-1 and NO in human umbilical vein endothelial cells.

Journal: Chinese medical journal20030601

Title: ANP but not BNP reflects early left diastolic dysfunction in type 1 diabetics with myocardial dysinnervation.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme20030501

Title: Comparison of dipyridamole and fosinopril on renal progression in nephrectomized rats.

Journal: Nephrology (Carlton, Vic.)20030401

Title: A prospective, randomized, open labeled crossover trial of fosinopril and theophylline in post renal transplant erythrocytosis.

Journal: Renal failure20030101

Title: [Chronopharmacological approaches to the therapeutic prophylaxis of chronic cardiac insufficiency in type I diabetes mellitus].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk20030101

Title: [Tongue angioedema associated with angiotensin-converting enzyme inhibitor (diagnosis, differential diagnosis, treatment)].

Journal: Medicina (Kaunas, Lithuania)20030101

Title: [Efficacy of combined use of fosinopril and propranolol in acute myocardial infarction].

Journal: Kardiologiia20030101

Title: Precipitation of PTSD with metoprolol for hypertension.

Journal: Psychosomatics20030101

Title: Effects of amlodipine fosinopril combination on microalbuminuria in hypertensive type 2 diabetic patients.

Journal: American journal of hypertension20021201

Title: Drug effects on aldosterone/plasma renin activity ratio in primary aldosteronism.

Journal: Hypertension (Dallas, Tex. : 1979)20021201

Title: Regression of ventricular and vascular hypertrophy: are there differences between structurally different angiotensin-converting enzyme inhibitors?

Journal: Journal of hypertension20021201

Title: [Comparison of the antihypertensive activity of fosinopril and irbesartan].

Journal: Anales de medicina interna (Madrid, Spain : 1984)20021101

Title: The effects of losartan and fosinopril in hypertensive type 2 diabetic patients.

Journal: Diabetes research and clinical practice20021001

Title: Physiologic consequences of vasopeptidase inhibition in humans: effect of sodium intake.

Journal: Journal of the American Society of Nephrology : JASN20021001

Title: Hemodynamic and humoral effects of vasopeptidase inhibition in canine hypertension.

Journal: Hypertension (Dallas, Tex. : 1979)20021001

Title: FOSIDIAL: a randomised placebo controlled trial of the effects of fosinopril on cardiovascular morbidity and mortality in haemodialysis patients. Study design and patients' baseline characteristics.

Journal: Fundamental & clinical pharmacology20021001

Title: Apoptosis, myocardial fibrosis and angiotensin II in the left ventricle of hypertensive rats treated with fosinopril or losartan.

Journal: Chinese medical journal20020901

Title: Using ACE inhibitors appropriately.

Journal: American family physician20020801

Title: Safe drug prescribing.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne20020625

Title: Fosinopril-induced hepatotoxicity in a complex medical patient.

Journal: Tennessee medicine : journal of the Tennessee Medical Association20020401

Title: Simultaneous determination of fosinopril and hydrochlorothiazide in pharmaceutical formulations by spectrophotometric methods.

Journal: Journal of pharmaceutical and biomedical analysis20020301

Title: Fosinopril improves left ventricular diastolic function in young mildly hypertensive patients without hypertrophy.

Journal: Cardiovascular drugs and therapy20020301

Title: Fosinopril versus amlodipine comparative treatments study: a randomized trial to assess effects on plasminogen activator inhibitor-1.

Journal: Circulation20020129

Title: Additive antiproteinuric effect of combined ACE inhibition and angiotensin II receptor blockade.

Journal: Journal of hypertension20020101

Title: Fosinopril as a possible pemphigus-inducing drug.

Journal: Dermatology (Basel, Switzerland)20020101

Title: Fixed combinations of delapril plus indapamide vs fosinopril plus hydrochlorothiazide in mild to moderate essential hypertension.

Journal: Advances in therapy20020101

Title: [Renoprotective effect of monopril in patients with diabetes mellitus in the preclinical stage of diabetic nephropathy].

Journal: Likars'ka sprava20020101

Title: [Changes of distensibility of the aorta in elderly patients during long-term therapy with various classes of hypotensive drugs (magnetic resonance tomography data)].

Journal: Kardiologiia20020101

Title: [FLAG--a program of achievability of target blood pressure levels during treatment of patients with hypertension with fosinopril].

Journal: Kardiologiia20020101

Title: The effect and mechanism of forsinopril on ventricular hypertrophy of SHR and left ventricular pressure overloading rat.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban20020101

Title: The cardiovascular actions of omapatrilat in spontaneously hypertensive rats.

Journal: Current hypertension reports20011201

Title: Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats.

Journal: International journal of cardiology20011201

Title: ACE inhibitor-induced angioedema of the intestine: Case report, incidence, pathophysiology, diagnosis and management.

Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie20011201

Title: [Effectiveness and tolerance of fosinopril in the treatment of arterial hypertension of mild and medium severity].

Journal: Vnitrni lekarstvi20011201

Title: [Contrast of losartan, fosinopril and amlodipine on cardiomyocyte apoptosis and left ventricular remolding in hypertensive rats].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University20011028

Title: Mechanism of intestinal absorption and renal reabsorption of an orally active ace inhibitor: uptake and transport of fosinopril in cell cultures.

Journal: Drug metabolism and disposition: the biological fate of chemicals20011001

Title: Effects of combination of angiotensin-converting enzyme inhibitor and angiotensin receptor antagonist on inflammatory cellular infiltration and myocardial interstitial fibrosis after acute myocardial infarction.

Journal: Journal of the American College of Cardiology20011001

Title: Angiotensin converting enzyme inhibition improves cardiac neuronal uptake of noradrenaline in spontaneously hypertensive rats.

Journal: Journal of hypertension20011001

Title: A random comparison of fosinopril and nifedipine GITS in patients with primary renal disease.

Journal: Journal of hypertension20011001

Title: Angiotensin-converting enzyme inhibition induces apoptosis in erythroid precursors and affects insulin-like growth factor-1 in posttransplantation erythrocytosis.

Journal: Journal of the American Society of Nephrology : JASN20010901

Title: Vasopeptidase inhibition attenuates the progression of renal injury in subtotal nephrectomized rats.

Journal: Kidney international20010801

Title: Endogenous natriuretic peptides participate in renal and humoral actions of acute vasopeptidase inhibition in experimental mild heart failure.

Journal: Hypertension (Dallas, Tex. : 1979)20010801

Title: Hepatotoxicity induced by fosinopril.

Journal: Journal of hepatology20010801

Title: The effects of ACE inhibitor therapy on left ventricular myocardial mass and diastolic filling in previously untreated hypertensive patients: a cine MRI study.

Journal: Journal of magnetic resonance imaging : JMRI20010701

Title: Effects of fosinopril on renal function, baroreflex response and noradrenaline pressor response in conscious normotensive dogs.

Journal: Veterinary research communications20010701

Title: [Effects of lorsartan, fosinopril on myocardial fibrosis, angiotensin II and cardiac remolding in hypertensive rats].

Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University20010428

Title: Fosinopril-induced prolonged cholestatic jaundice and pruritus: first case report.

Journal: European journal of gastroenterology & hepatology20010301

Title: Comparison of the first dose response of fosinopril and captopril in congestive heart failure: a randomized, double-blind, placebo controlled study.

Journal: Japanese heart journal20010301

Title: Systolic and pulse blood pressures (but not diastolic blood pressure and serum cholesterol) are associated with alterations in carotid intima-media thickness in the moderately hypercholesterolaemic hypertensive patients of the Plaque Hypertension Lipid Lowering Italian Study. PHYLLIS study group.

Journal: Journal of hypertension20010101

Title: Effects of omapatrilat on blood pressure and insulin sensitivity in an animal model of insulin resistance.

Journal: Blood pressure20010101

Title: Effects of spironolactone and fosinopril on the spontaneous and chronic ventricular arrhythmias in a rat model of myocardial infarction.

Journal: Cardiology20010101

Title: Cocaine, HIV, and their cardiovascular effects: is there a role for ACE-inhibitor therapy?

Journal: Drug and alcohol dependence20001222

Title: Effect of valsartan and fosinopril on catecholamine-induced cardiac hypertrophy.

Journal: Acta pharmacologica Sinica20000901

Title: The hemodynamic effects of long-term ACE inhibition with fosinopril in patients with heart failure. Fosinopril Hemodynamics Study Group.

Journal: American journal of therapeutics19990701

Title: Elevation of serum creatinine following fosinopril therapy.

Journal: The Annals of pharmacotherapy19990301

Title: New evidence on the prevention of cardiovascular events in hypertensive patients with type 2 diabetes.

Journal: Journal of cardiovascular pharmacology19980101

Title: Effects of atenolol as add-on therapy to fosinopril in heart failure.

Journal: Wiener klinische Wochenschrift19970411

Title: Albuminuria and transferrinuria in essential hypertension. Effects of antihypertensive therapy.

Journal: American journal of hypertension19961101

Title: [Evaluation of the total hepatic function after treatment with fosinopril in hypertensive patients with liver cirrhosis].

Journal: La Clinica terapeutica19941201

Title: Disparate cardiovascular response to stress tests during isradipine and fosinopril therapy.

Journal: The American journal of cardiology19930901

Title: Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology.

Journal: Journal of cardiovascular pharmacology19891101

Title: Ondetti, M.A., Structural relationships of angiotensin converting-enzyme inhibitors to pharmacologic activity. Circulation, 1988. 77(6 Pt 2): p. I74-8.

Title: Piepho, R.W., Overview of the angiotensin-converting-enzyme inhibitors. Am J Health Syst Pharm, 2000. 57 Suppl 1: p. S3-7.

Title: Sharma, S., et al., The hemodynamic effects of long-term ACE inhibition with fosinopril in patients with heart failure. Fosinopril Hemodynamics Study Group. Am J Ther, 1999. 6(4): p. 181-9.

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