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93-51-6,MFCD00002378
Catalog No.:AA00IHD7

93-51-6 | 2-Methoxy-4-methylphenol

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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00IHD7
Chemical Name:
2-Methoxy-4-methylphenol
CAS Number:
93-51-6
Molecular Formula:
C8H10O2
Molecular Weight:
138.1638
MDL Number:
MFCD00002378
SMILES:
COc1cc(C)ccc1O
NSC Number:
4969
FEMA Number:
2671
Properties
Properties
 
BP:
221.0°C  
Form:
Liquid  
MP:
5 °C(lit.)  
Refractive Index:
n20/D 1.537(lit.)  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
103  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
1.3  

Upstream Synthesis Route

[1]AustralianJournalofChemistry,1973,vol.26,p.1337-1351

Downstream Synthesis Route

[1]CurrentPatentAssignee:KATHOLIEKEUNIVERSITEITLEUVEN-WO2018/134427,2018,A1Locationinpatent:Page/Pagecolumn30;31;35

[2]Locationinpatent:experimentalpartMeylemans,HeatherA.;Groshens,ThomasJ.;Harvey,BenjaminG.[ChemSusChem,2012,vol.5,#1,p.206-210]

[3]CurrentPatentAssignee:GOVERNMENTOFTHEUNITEDSTATES-US10252966,2019,B1Locationinpatent:Page/Pagecolumn11

[4]Chen,Qin;Gao,Keke;Peng,Chang;Xie,Haibo;Zhao,ZongbaoKent;Bao,Ming[GreenChemistry,2015,vol.17,#9,p.4546-4551]

[5]Arcoleo;Garofano[AnnalidiChimica,1957,vol.47,p.1142,1161]

[1]Tiemann;Koppe[ChemischeBerichte,1881,vol.14,p.2021]

[2]Krajniak,E.R.etal.[AustralianJournalofChemistry,1973,vol.26,p.1337-1351]

[1]Zhang,Yuecheng;Li,Xiujuan;Cao,Xiaohui;Zhao,Jiquan[ResearchonChemicalIntermediates,2014,vol.40,#3,p.1303-1311]

[2]Liang,Cheng;Li,Xuefeng;Su,Diefeng;Ma,Qiyi;Mao,Jianyong;Chen,Zhirong;Wang,Yong;Yao,Jia;Li,Haoran[Molecularcatalysis,2018,vol.453,p.121-131]

[3]Jiang,Jian-An;Du,Jia-Lei;Liao,Dao-Hua;Wang,Zhan-Guo;Ji,Ya-Fei[TetrahedronLetters,2014,vol.55,#8,p.1406-1411]

[4]Zhang,Jin;Du,Jihong;Zhang,Chenyang;Liu,Kun;Yu,Feifei;Yuan,Yongkun;Duan,Baogen;Liu,Renhua[OrganicLetters,2022,vol.24,#5,p.1152-1157]

[5]Ono;Imoto[BulletinoftheChemicalSocietyofJapan,1936,vol.11,p.127,131][NipponKagakuKaishi,1936,vol.57,p.112,118]

[6]Ma,Wenchan;Zhang,Yuecheng;Li,Xiujuan;Zhao,Jiquan[ResearchonChemicalIntermediates,2015,vol.41,#6,p.3855-3863]

[7]Ma,Qiyi;Liang,Cheng;Chen,Kexian;Liu,Kejing;Mao,Jianyong;Chen,Zhirong;Li,Haoran[JournalofMolecularCatalysisA:Chemical,2016,vol.420,p.45-49]

[8]CurrentPatentAssignee:ZHEJIANGNHUCO.,LTD.;ZHEJIANGUNIVERSITY-CN106986756,2017,ALocationinpatent:Paragraph0069-0072

[9]Hu,Jinghui;Hu,Yifan;Chen,Zhirong;Li,Haoran;Mao,Jianyong;Yao,Jia[GreenChemistry,2012,vol.14,#10,p.2894-2898,5]

[1]Synthesis,1985,p.437-439

[2]Patent:CN108821930,2018,A.Locationinpatent:Paragraph0078-0080

[3]Synthesis,2019,vol.51,p.704-712

[4]JournalofOrganicChemistry,2020,vol.85,p.6429-6440

[5]ChemischeBerichte,1881,vol.14,p.2021

[6]BulletindelaSocieteChimiquedeFrance,1893,vol.<3>9,p.145

[7]ComptesRendusHebdomadairesdesSeancesdel'AcademiedesSciences,1892,vol.115,p.234    BulletindelaSocieteChimiquedeFrance,1893,vol.<3>9,p.53

[8]AnnalesdeChimie(Cachan,France),1898,vol.<7>13,p.497

[9]RecueildesTravauxChimiquesdesPays-Bas,1909,vol.28,p.287,288

[10]ChemischeBerichte,1881,vol.14,p.2021

[11]ChemischeBerichte,1892,vol.25,p.3533

[1]CurrentPatentAssignee:Syngenta(in:SinochemHoldings);SINOCHEMHOLDINGSCORPORATIONLTD-WO2017/216191,2017,A1Locationinpatent:Page/Pagecolumn19-20

[2]Fuson;Gaertner;Chadwick[JournalofOrganicChemistry,1948,vol.13,p.489,493]Manske;Ledingham[CanadianJournalofResearch,SectionB:ChemicalSciences,1944,vol.22,p.115,123]

[3]Vierhapper,F.W.etal.[MonatsheftefurChemie,1975,vol.106,p.1191-1201]

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Tags:93-51-6 Molecular Formula|93-51-6 MDL|93-51-6 SMILES|93-51-6 2-Methoxy-4-methylphenol