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71963-77-4,MFCD00866205
Catalog No.:AA00IKG4

71963-77-4 | Artemether

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1g
98%(HPLC)
in stock  
$37.00   $26.00
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5g
>98.0%(HPLC)
in stock  
$92.00   $64.00
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25g
>98.0%(HPLC)
in stock  
$271.00   $190.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00IKG4
Chemical Name:
Artemether
CAS Number:
71963-77-4
Molecular Formula:
C16H26O5
Molecular Weight:
298.3746
MDL Number:
MFCD00866205
SMILES:
CO[C@H]1O[C@@H]2O[C@@]3(C)CC[C@@H]4[C@]2([C@H]([C@H]1C)CC[C@H]4C)OO3
Properties
Computed Properties
 
Complexity:
429  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
1  
XLogP3:
3.1  

Literature

Title: Fetal bovine serum and human constitutive androstane receptor: evidence for activation of the SV23 splice variant by artemisinin, artemether, and arteether in a serum-free cell culture system.

Journal: Toxicology and applied pharmacology 20140601

Title: Transdermal glyceryl trinitrate as an effective adjunctive treatment with artemether for late-stage experimental cerebral malaria.

Journal: Antimicrobial agents and chemotherapy 20131101

Title: Synthesis and antimalarial efficacy of two-carbon-linked, artemisinin-derived trioxane dimers in combination with known antimalarial drugs.

Journal: Journal of medicinal chemistry 20130328

Title: Antimalarial activity of 10-alkyl/aryl esters and -aminoethylethers of artemisinin.

Journal: Bioorganic chemistry 20130201

Title: Use of artemether-lumefantrine to treat malaria during pregnancy: what do we know and need to know?

Journal: Expert review of anti-infective therapy 20130201

Title: A SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs.

Journal: Malaria journal 20130101

Title: Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation.

Journal: The Journal of antimicrobial chemotherapy 20121101

Title: The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an artemisinin derivative.

Journal: Life sciences 20121015

Title: Why do Plasmodium malariae infections sometimes occur in spite of previous antimalarial medication?

Journal: Parasitology research 20120801

Title: In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes.

Journal: The Journal of infectious diseases 20120801

Title: Increased urinary frequency: an unusual presentation of Plasmodium falciparum malaria.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20120701

Title: New treatment policy of malaria as a part of malaria control program in Indonesia.

Journal: Acta medica Indonesiana 20120701

Title: Coumarin-trioxane hybrids: synthesis and evaluation as a new class of antimalarial scaffolds.

Journal: Bioorganic & medicinal chemistry letters 20120615

Title: Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica.

Journal: Veterinary parasitology 20120525

Title: Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

Journal: Journal of medicinal chemistry 20120308

Title: Successful oral therapy for severe falciparum malaria: the World Health Organization criteria revisited.

Journal: The American journal of tropical medicine and hygiene 20120301

Title: Antimalarial drug interactions of compounds isolated from Kigelia africana (Bignoniaceae) and their synergism with artemether, against the multidrug-resistant W2mef Plasmodium falciparum strain.

Journal: Parasitology research 20120201

Title: Neuroschistosomiasis.

Journal: Journal of neurology 20120101

Title: Colpodella spp.-like parasite infection in woman, China.

Journal: Emerging infectious diseases 20120101

Title: Falciparum--the masquerader.

Journal: JPMA. The Journal of the Pakistan Medical Association 20120101

Title: Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.

Journal: Malaria journal 20120101

Title: Identification of the Schistosoma mansoni molecular target for the antimalarial drug artemether.

Journal: Journal of chemical information and modeling 20111128

Title: Metabolite identification of artemether by data-dependent accurate mass spectrometric analysis using an LTQ-Orbitrap hybrid mass spectrometer in combination with the online hydrogen/deuterium exchange technique.

Journal: Rapid communications in mass spectrometry : RCM 20111115

Title: Monitoring of artemisinin, dihydroartemisinin, and artemether in environmental matrices using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Journal: Journal of agricultural and food chemistry 20111109

Title: Efficacy of ginkgolic acids against Cryptosporidium andersoni in cell culture.

Journal: Parasitology research 20111101

Title: Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivo.

Journal: International immunopharmacology 20111101

Title: Plasmodium species co-infection as a cause of treatment failure.

Journal: Travel medicine and infectious disease 20111101

Title: Functional characterization of CYP2B6 allelic variants in demethylation of antimalarial artemether.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20111001

Title: Presumptive treatment to reduce imported malaria among refugees from east Africa resettling in the United States.

Journal: The American journal of tropical medicine and hygiene 20111001

Title: Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials.

Journal: PLoS neglected tropical diseases 20110901

Title: Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum.

Journal: Parasitology research 20110801

Title: Schistosoma mansoni: N-acetylcysteine downregulates oxidative stress and enhances the antischistosomal activity of artemether in mice.

Journal: Experimental parasitology 20110701

Title: Glycyrrhiza glabra (Linn.) and Lavandula officinalis (L.) cell suspension cultures-based biotransformation of β-artemether.

Journal: Journal of natural medicines 20110701

Title: Severe Plasmodium knowlesi malaria in a tertiary care hospital, Sabah, Malaysia.

Journal: Emerging infectious diseases 20110701

Title: Plasmodium knowlesi reinfection in human.

Journal: Emerging infectious diseases 20110701

Title: Artemether shows promising female schistosomicidal and ovicidal effects on the Egyptian strain of Schistosoma mansoni after maturity of infection.

Journal: Parasitology research 20110501

Title: Preparation of molecularly imprinted polymers for artemisinin based on the surfaces of silica gel.

Journal: Journal of biotechnology 20110420

Title: The multiple-dosing pharmacokinetics of artemether, artesunate, and their metabolite dihydroartemisinin in rats.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110301

Title: [In vitro effect of seven anthelmintic agents against adult Clonorchis sinensis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20110227

Title: Effect of mefloquine administered orally at single, multiple, or combined with artemether, artesunate, or praziquantel in treatment of mice infected with Schistosoma japonicum.

Journal: Parasitology research 20110201

Title: Synthesis and antimalarial activity of ethylene glycol oligomeric ethers of artemisinin.

Journal: The Journal of pharmacy and pharmacology 20110201

Title: Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether and their major metabolites dihydroartemisinin and dihydroartemisinin-glucuronide in sheep plasma.

Journal: Journal of mass spectrometry : JMS 20110201

Title: Toxicokinetic and toxicodynamic (TK/TD) evaluation to determine and predict the neurotoxicity of artemisinins.

Journal: Toxicology 20110111

Title: Liquid chromatography-tandem mass spectrometry for the simultaneous quantitation of artemether and lumefantrine in human plasma: application for a pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20110105

Title: Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection.

Journal: Journal of pharmaceutical and biomedical analysis 20110105

Title: In-vitro culture of Plasmodium falciparum: utility of modified (RPNI) medium for drug-sensitivity studies using SYBR Green I assay.

Journal: Experimental parasitology 20110101

Title: Automated erythrocytapheresis for severe falciparum malaria.

Journal: Internal medicine journal 20110101

Title: Comparative study of the efficacy and tolerability of dihydroartemisinin-piperaquine-trimethoprim versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Cameroon, Ivory Coast and Senegal.

Journal: Malaria journal 20110101

Title: Similar efficacy and safety of artemether-lumefantrine (Coartem®) in African infants and children with uncomplicated falciparum malaria across different body weight ranges.

Journal: Malaria journal 20110101

Title: Therapeutic efficacy and effect on gametocyte carriage of an artemisinin and a non-based combination treatment in children with uncomplicated P. falciparum malaria, living in an area with high-level chloroquine resistance.

Journal: Journal of tropical pediatrics 20101201

Title: Artemisinin-based combination therapies and their introduction in Japan.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20101201

Title: Association between the pfmdr1 gene and in vitro artemether and lumefantrine sensitivity in Thai isolates of Plasmodium falciparum.

Journal: The American journal of tropical medicine and hygiene 20101105

Title: Waking the sleeping beauty.

Journal: The Journal of infectious diseases 20101101

Title: Increased risk of early vomiting among infants and young children treated with dihydroartemisinin-piperaquine compared with artemether-lumefantrine for uncomplicated malaria.

Journal: The American journal of tropical medicine and hygiene 20101005

Title: Spiroindolones, a potent compound class for the treatment of malaria.

Journal: Science (New York, N.Y.) 20100903

Title: Effect of artemether, artesunate, OZ78, praziquantel, and tribendimidine alone or in combination chemotherapy on the tegument of Clonorchis sinensis.

Journal: Parasitology international 20100901

Title: Praziquantel efficacy in mice infected with PZQ non-susceptible S. mansoni isolate treated with artemether: parasitological, biochemical and immunohistochemical assessment.

Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20100901

Title: Azithromycin combination therapy for the treatment of uncomplicated falciparum malaria in Bangladesh: an open-label randomized, controlled clinical trial.

Journal: The Journal of infectious diseases 20100815

Title: Arthemeter-loaded lipid nanoparticles produced by modified thin-film hydration: Pharmacokinetics, toxicological and in vivo anti-malarial activity.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100811

Title: Tegumental surface changes in adult Paramphistomum microbothrium (Fischoeder 1901) following in vitro administration of artemether.

Journal: Journal of helminthology 20100601

Title: Physicochemical characterization of artemether solid dispersions with hydrophilic carriers by freeze dried and melt methods.

Journal: Archives of pharmacal research 20100601

Title: Palatable reconstitutable dry suspension of artemether for flexible pediatric dosing using cyclodextrin inclusion complexation.

Journal: Pharmaceutical development and technology 20100601

Title: Determination of beta-artemether and its main metabolite dihydroartemisinin in plasma employing liquid-phase microextraction prior to liquid chromatographic-tandem mass spectrometric analysis.

Journal: Talanta 20100515

Title: Thiazole, oxadiazole, and carboxamide derivatives of artemisinin are highly selective and potent inhibitors of Toxoplasma gondii.

Journal: Journal of medicinal chemistry 20100513

Title: Synthesis, in vitro and in vivo antimalarial assessment of sulfide, sulfone and vinyl amide-substituted 1,2,4-trioxanes prepared via thiol-olefin co-oxygenation (TOCO) of allylic alcohols.

Journal: Organic & biomolecular chemistry 20100507

Title: Toxicity of the antimalarial artemisinin and its dervatives.

Journal: Critical reviews in toxicology 20100501

Title: Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.

Journal: Antimicrobial agents and chemotherapy 20100501

Title: Pyronaridine-artesunate for uncomplicated falciparum malaria.

Journal: Lancet (London, England) 20100424

Title: Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial.

Journal: Lancet (London, England) 20100424

Title: Evaluation of drug effects on Toxoplasma gondii nuclear and plastid DNA replication using real-time PCR.

Journal: Parasitology research 20100401

Title: Neurotoxic effects of 25mg/kg/bodyweight of artemether on the histology of the trapezoid nuclei and behavioural functions in adult male Wistar rats.

Journal: Acta histochemica 20100301

Title: Fasciola gigantica: Parasitological and scanning electron microscopy study of the in vitro effects of ivermectin and/or artemether.

Journal: Experimental parasitology 20100301

Title: Cerebral malaria: a vasculopathy.

Journal: The American journal of pathology 20100301

Title: Murine cerebral malaria is associated with a vasospasm-like microcirculatory dysfunction, and survival upon rescue treatment is markedly increased by nimodipine.

Journal: The American journal of pathology 20100301

Title: Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.

Journal: Journal of medicinal chemistry 20100128

Title: Activity of artemether and mefloquine against juvenile and adult Schistosoma mansoni in athymic and immunocompetent NMRI mice.

Journal: The American journal of tropical medicine and hygiene 20100101

Title: A randomized trial of artesunate mefloquine versus artemether lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Senegalese children.

Journal: The American journal of tropical medicine and hygiene 20100101

Title: Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria.

Journal: Malaria journal 20100101

Title: Artemisinin-derived dimers have greatly improved anti-cytomegalovirus activity compared to artemisinin monomers.

Journal: PloS one 20100101

Title: Incidence of malaria and efficacy of combination antimalarial therapies over 4 years in an urban cohort of Ugandan children.

Journal: PloS one 20100101

Title: Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine.

Journal: Malaria journal 20100101

Title: High performance liquid chromatographic evaluation of artemisinin, raw material in the synthesis of artesunate and artemether.

Journal: Journal of chromatography. A 20091218

Title: Development and validation of a high-performance liquid chromatography/tandem mass spectrometry method for the determination of artemether and its active metabolite dihydroartemisinin in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis 20091205

Title: Efficacy of artesunate and artemether against Clonorchis sinensis in rabbits.

Journal: Parasitology research 20091201

Title: Azithromycin plus artesunate versus artemether-lumefantrine for treatment of uncomplicated malaria in Tanzanian children: a randomized, controlled trial.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20091015

Title: Comparative in vitro effect of artemether and albendazole on adult Toxocara canis.

Journal: Parasitology research 20091001

Title: Artemether/hydroxypropyl-beta-cyclodextrin host-guest system: characterization, phase-solubility and inclusion mode.

Journal: Bioorganic & medicinal chemistry 20090901

Title: Lopinavir/ritonavir affects pharmacokinetic exposure of artemether/lumefantrine in HIV-uninfected healthy volunteers.

Journal: Journal of acquired immune deficiency syndromes (1999) 20090801

Title: Evaluation of the developmental toxicity of artemether during different phases of rat pregnancy.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090701

Title: [Preparation and characterization of artemether-iron sucrose lipid nanoparticles].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090701

Title: Mild increases in serum hepcidin and interleukin-6 concentrations impair iron incorporation in haemoglobin during an experimental human malaria infection.

Journal: British journal of haematology 20090601

Title: Adult triclabendazole-resistant Fasciola hepatica: morphological changes in the tegument and gut following in vivo treatment with artemether in the rat model.

Journal: Journal of helminthology 20090601

Title: First artemisinin-based antimalarial combination approved for U.S. market.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090515

Title: Treatment of severe sepsis with artemether-lumefantrine is associated with decreased mortality in Ugandan patients without malaria.

Journal: The American journal of tropical medicine and hygiene 20090501

Title: Antitumour and antimalarial activity of artemisinin-acridine hybrids.

Journal: Bioorganic & medicinal chemistry letters 20090401

Title: Semi-synthetic and synthetic 1,2,4-trioxaquines and 1,2,4-trioxolaquines: synthesis, preliminary SAR and comparison with acridine endoperoxide conjugates.

Journal: Bioorganic & medicinal chemistry letters 20090401

Title: A liquid chromatographic-tandem mass spectrometric method for determination of artemether and its metabolite dihydroartemisinin in human plasma.

Journal: Bioanalysis 20090401

Title: Antimalarial therapies in children from Papua New Guinea.

Journal: The New England journal of medicine 20090319

Title: In vitro effect of artemether and triclabendazole on adult Fasciola gigantica.

Journal: Veterinary parasitology 20090309

Title: Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model.

Journal: Integrative cancer therapies 20090301

Title: [Experimental study progress on tribendimidine, artemether and artesunate against Clonorchis sinensis and other trematodes].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20090227

Title: Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.

Journal: Journal of medicinal chemistry 20090226

Title: Effect of single-dose oral artemether and tribendimidine on the tegument of adult Clonorchis sinensis in rats.

Journal: Parasitology research 20090201

Title: Synthesis and biological evaluation of extraordinarily potent C-10 carba artemisinin dimers against P. falciparum malaria parasites and HL-60 cancer cells.

Journal: Bioorganic & medicinal chemistry 20090201

Title: Advances in global biotechnology and local resources to treat malaria.

Journal: Minnesota medicine 20090201

Title: [Effects of artemether and dihydroarteannuin on mouse model of scleroderma].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090101

Title: The clinical efficacy of artemether/lumefantrine (Coartem).

Journal: Malaria journal 20090101

Title: Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial.

Journal: PloS one 20090101

Title: Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children.

Journal: Malaria journal 20090101

Title: Cardiac complication after experimental human malaria infection: a case report.

Journal: Malaria journal 20090101

Title: A trial of combination antimalarial therapies in children from Papua New Guinea.

Journal: The New England journal of medicine 20081211

Title: Design and optimization of artemether microparticles for bitter taste masking.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20081201

Title: A randomised controlled trial of artemether-lumefantrine versus artesunate for uncomplicated plasmodium falciparum treatment in pregnancy.

Journal: PLoS medicine 20081201

Title: Design and in vivo pharmacodynamic evaluation of nanostructured lipid carriers for parenteral delivery of artemether: Nanoject.

Journal: International journal of pharmaceutics 20081119

Title: Simultaneous determination of artemether and lumefantrine in fixed dose combination tablets by HPLC with UV detection.

Journal: Journal of pharmaceutical and biomedical analysis 20081104

Title: Piperidine dispiro-1,2,4-trioxane analogues.

Journal: Bioorganic & medicinal chemistry letters 20081101

Title: A randomized trial of artesunate-mefloquine versus artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Mali.

Journal: The American journal of tropical medicine and hygiene 20081101

Title: [Effect of tribendimidine, artesunate, artemether and praziquantel, administered intragastrically at single, multiple or combined doses, to rats infected with Clonorchis sinensis].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20081030

Title: Solid microemulsion preconcentrate (NanOsorb) of artemether for effective treatment of malaria.

Journal: International journal of pharmaceutics 20081001

Title: Development of SMEDDS using natural lipophile: application to beta-Artemether delivery.

Journal: International journal of pharmaceutics 20081001

Title: A randomized, double-blind, placebo-controlled trial of safety and efficacy of combined praziquantel and artemether treatment for acute schistosomiasis japonica in China.

Journal: Bulletin of the World Health Organization 20081001

Title: Adherence and efficacy of supervised versus non-supervised treatment with artemether/lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Bangladesh: a randomised controlled trial.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20080901

Title: Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080901

Title: Efficacy and safety of artemether against a natural Fasciola hepatica infection in sheep.

Journal: Parasitology research 20080801

Title: Developmental toxicity of artesunate in the rat: comparison to other artemisinins, comparison of embryotoxicity and kinetics by oral and intravenous routes, and relationship to maternal reticulocyte count.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20080801

Title: Development and evaluation of artemether taste masked rapid disintegrating tablets with improved dissolution using solid dispersion technique.

Journal: AAPS PharmSciTech 20080601

Title: Artemether treatment of prepatent Schistosoma japonicum induces resistance to reinfection in association with reduced pathology.

Journal: The American journal of tropical medicine and hygiene 20080601

Title: [Studies on pharmacokinetics of artemether patch in mice].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601

Title: Anti-protozoan activities of Harungana madagascariensis stem bark extract on trichomonads and malaria.

Journal: Journal of ethnopharmacology 20080522

Title: High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria.

Journal: Tropical medicine & international health : TM & IH 20080501

Title: Electronically stabilized versions of the antimalarial acetal trioxanes artemether and artesunate.

Journal: Bioorganic & medicinal chemistry 20080501

Title: [Effect of several penetration enharcers on transdermal permeation and skin accumulation of artemether].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080501

Title: Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.

Journal: Journal of medicinal chemistry 20080410

Title: Changes in antioxidant status and biochemical indices after acute administration of artemether, artemether-lumefantrine and halofantrine in rats.

Journal: Basic & clinical pharmacology & toxicology 20080401

Title: The use of artemether-lumefantrine by febrile children following national implementation of a revised drug policy in Kenya.

Journal: Tropical medicine & international health : TM & IH 20080401

Title: A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens.

Journal: Journal of pharmacokinetics and pharmacodynamics 20080401

Title: Effect of chitosan crosslinking on bitterness of artemether using response surface methodology.

Journal: The Journal of pharmacy and pharmacology 20080401

Title: Impaired clinical response in a patient with uncomplicated falciparum malaria who received poor-quality and underdosed intramuscular artemether.

Journal: The American journal of tropical medicine and hygiene 20080401

Title: Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum.

Journal: Journal of medicinal chemistry 20080313

Title: An efficient route into synthetically challenging bridged achiral 1,2,4,5-tetraoxanes with antimalarial activity.

Journal: Bioorganic & medicinal chemistry letters 20080301

Title: [Efficacy of dihydroartemisinin-piperaquine and artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in Hainan, China].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20080227

Title: Fasciola hepatica: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether.

Journal: Experimental parasitology 20080201

Title: Artemether and tribendimidine lack activity in experimental treatment of Paragonimus westermani in the dog.

Journal: Parasitology research 20080201

Title: Plasmodium falciparum from Pará state (Brazil) shows satisfactory in vitro response to artemisinin derivatives and absence of the S769N mutation in the SERCA-type PfATPase6.

Journal: Tropical medicine & international health : TM & IH 20080201

Title: An interactive model for the assessment of the economic costs and benefits of different rapid diagnostic tests for malaria.

Journal: Malaria journal 20080101

Title: Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrine.

Journal: Malaria journal 20080101

Title: Artemisinin--an innovative cornerstone for anti-malaria therapy.

Journal: Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20080101

Title: Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda.

Journal: PloS one 20080101

Title: Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children.

Journal: Chemotherapy 20080101

Title: An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.

Journal: PloS one 20080101

Title: [Efficacy of artemether in the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6-60 months of age in Bangui (Central African Republic)].

Journal: Sante (Montrouge, France) 20080101

Title: Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children.

Journal: Malaria journal 20080101

Title: Ototoxicity of artemether/lumefantrine in the treatment of falciparum malaria: a randomized trial.

Journal: Malaria journal 20080101

Title: Malaria case-management under artemether-lumefantrine treatment policy in Uganda.

Journal: Malaria journal 20080101

Title: Trends in antimalarial prescriptions in Australia 2002 to 2005.

Journal: Journal of travel medicine 20080101

Title: Sublingual sugar for hypoglycaemia in children with severe malaria: a pilot clinical study.

Journal: Malaria journal 20080101

Title: Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20071201

Title: [Artemether-lumefantrine, treatment of child more than 5 years old uncomplicated malaria in Tsevie's hospital (Togo)].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20071201

Title: Malaria in Egypt, Saudi Arabia and Yemen: a clinical pilot study.

Journal: Journal of the Egyptian Society of Parasitology 20071201

Title: Immunohistopathological and biochemical changes in Schistosoma mansoni-infected mice treated with artemether.

Journal: The Journal of infection 20071101

Title: Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.

Journal: Clinical pharmacology and therapeutics 20071101

Title: Resistance to artemisinin derivatives along the Thai-Cambodian border.

Journal: Releve epidemiologique hebdomadaire 20071012

Title: [Treatment of falciparum malaria with artemether-lumefantrine according to a 5-day schedule: results of a study in 21 patients and recommendations].

Journal: Nederlands tijdschrift voor geneeskunde 20071006

Title: [The effect of gossypol, praziquantel and artemether on recombinant lactate dehydrogenase from Schistosoma japonicum].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20071001

Title: Treatment of Haemoproteus tinnunculi in falcons.

Journal: The Veterinary record 20070908

Title: Dissociative electron attachment to di-tert-butylperoxide, artemisinin, and beta-artemether.

Journal: The journal of physical chemistry. A 20070816

Title: [Blackwater fever in children during cerebral malaria: 3 case reports in Bamako].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20070801

Title: A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds.

Journal: Experimental parasitology 20070701

Title: Rectal administration of artemisinin derivatives for the treatment of malaria.

Journal: JAMA 20070606

Title: Cerebral malaria in children in South Sudan: 8 years experience in 261 cases.

Journal: Neuro endocrinology letters 20070601

Title: Ten years experience with 497 cases of neuroinfections in tropic: in limited laboratory infrastructure initially treat both, cerebral malaria and meningitis.

Journal: Neuro endocrinology letters 20070601

Title: Clinical efficacy of chloroquine versus artemether-lumefantrine for Plasmodium vivax treatment in Thailand.

Journal: The Korean journal of parasitology 20070601

Title: Effect of artemether on pentobarbitone sleep and electrical activity in rats.

Journal: Canadian journal of physiology and pharmacology 20070601

Title: Artesunate, artemether or quinine in severe Plasmodium falciparum malaria?

Journal: Expert review of anti-infective therapy 20070401

Title: In vitro and in vivo interaction of synthetic peroxide RBx11160 (OZ277) with piperaquine in Plasmodium models.

Journal: Experimental parasitology 20070301

Title: Investigation of the immunosuppressive activity of artemether on T-cell activation and proliferation.

Journal: British journal of pharmacology 20070301

Title: In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe.

Journal: Tropical medicine & international health : TM & IH 20070301

Title: Validated HPTLC method of analysis for artemether and its formulations.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: [Surveillance of falciparum malaria susceptibility to antimalarial drugs and policy change in the Comoros].

Journal: Bulletin de la Societe de pathologie exotique (1990) 20070201

Title: Assay of artemether, methylparaben and propylparaben in a formulated paediatric antimalarial dry suspension.

Journal: Journal of pharmaceutical and biomedical analysis 20070117

Title: Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria.

Journal: Expert opinion on pharmacotherapy 20070101

Title: Quality control of active ingredients in artemisinin-derivative antimalarials within Kenya and DR Congo.

Journal: Tropical medicine & international health : TM & IH 20070101

Title: Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian children.

Journal: The American journal of tropical medicine and hygiene 20070101

Title: Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal.

Journal: Malaria journal 20070101

Title: Efficacy and safety of artemisinin-based antimalarial in the treatment of uncomplicated malaria in children in southern Tanzania.

Journal: Malaria journal 20070101

Title: Modulation of the antioxidant defence in different developmental stages of Schistosoma mansoni by praziquantel and artemether.

Journal: British journal of biomedical science 20070101

Title: [Severe malaria: assessment of the treatment of anaemia and cerebral manifestations in a tropical intensive cares unit].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20061201

Title: The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicated falciparum malaria.

Journal: European journal of clinical pharmacology 20061201

Title: In vitro inhibition of Toxoplasma gondii by four new derivatives of artemisinin.

Journal: Antimicrobial agents and chemotherapy 20061201

Title: Case report of a pituitary macroadenoma treated with artemether.

Journal: Integrative cancer therapies 20061201

Title: Changes in the visceral functions of Plasmodium berghei-infected and -uninfected rats following administration of artemether.

Journal: Clinical and experimental pharmacology & physiology 20061201

Title: [Extraction of artemisinin and synthesis of its derivates artesunate and artemether].

Journal: Medecine tropicale : revue du Corps de sante colonial 20061201

Title: Effect of artemether on the tegument of adult Schistosoma haematobium recovered from mice.

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20061201

Title: Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine.

Journal: Bioorganic & medicinal chemistry letters 20061101

Title: HIV-1 immune suppression and antimalarial treatment outcome in Zambian adults with uncomplicated malaria.

Journal: The Journal of infectious diseases 20061001

Title: Effect of artesunate and artemether against Clonorchis sinensis and Opisthorchis viverrini in rodent models.

Journal: International journal of antimicrobial agents 20061001

Title: A randomized trial of artesunate-sulfamethoxypyrazine-pyrimethamine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Mali.

Journal: The American journal of tropical medicine and hygiene 20061001

Title: Ultrastructural alterations of adult schistosoma haematobium harbored in mice following artemether administration.

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20061001

Title: First Brazilian experience with the use of artemether-lumefantrine (Coartem) a fixed-dosed ACT combination.

Journal: The American journal of tropical medicine and hygiene 20060801

Title: The financial and clinical implications of adult malaria diagnosis using microscopy in Kenya.

Journal: Tropical medicine & international health : TM & IH 20060801

Title: [Therapeutic alternatives in case of failure of first-line treatment of intestinal helminthiasis in adults].

Journal: Medecine tropicale : revue du Corps de sante colonial 20060801

Title: Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.

Journal: Experimental parasitology 20060701

Title: In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum.

Journal: The Journal of antimicrobial chemotherapy 20060701

Title: Effect of artemether administered alone or in combination with praziquantel to mice infected with Plasmodium berghei or Schistosoma mansoni or both.

Journal: International journal for parasitology 20060701

Title: Feasibility and acceptability of the use of artemether-lumefantrine in the home management of uncomplicated malaria in children 6-59 months old in Ghana.

Journal: Tropical medicine & international health : TM & IH 20060701

Title: High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola.

Journal: The American journal of tropical medicine and hygiene 20060701

Title: Artesunate and artemether are effective fasciolicides in the rat model and in vitro.

Journal: The Journal of antimicrobial chemotherapy 20060601

Title: Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060601

Title: Efficacy and safety of the six-dose regimen of artemether-lumefantrine in pediatrics with uncomplicated Plasmodium falciparum malaria: a pooled analysis of individual patient data.

Journal: The American journal of tropical medicine and hygiene 20060601

Title: Malaria: severe, life threatening.

Journal: Clinical evidence 20060601

Title: Determination of the antimalaria drug artemether in pharmaceutical preparations by differential pulse polarography.

Journal: Journal of pharmaceutical and biomedical analysis 20060503

Title: Examples of tropical disease control in the humanitarian medical programmes of MSF and Merlin.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20060401

Title: Predictors of the failure of treatment with pyrimethamine-sulfadoxine in children with uncomplicated falciparum malaria.

Journal: Acta tropica 20060401

Title: Operational response to malaria epidemics: are rapid diagnostic tests cost-effective?

Journal: Tropical medicine & international health : TM & IH 20060401

Title: Intermediate-term toxicity of repeated orally administered doses of the anti-malarial beta-artemether in dogs.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060301

Title: Effects of artemisinin, artemether, and arteether on the pharmacokinetics of phenytoin.

Journal: Methods and findings in experimental and clinical pharmacology 20060301

Title: Effects of weight, age, and time on artemether-lumefantrine associated ototoxicity and evidence of irreversibility.

Journal: Travel medicine and infectious disease 20060301

Title: [The microfluorimetric assay (MFA) in in vitro testing the sensitivity of Plasmodium falciparum to antimalarial drugs].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20060227

Title: A case-control auditory evaluation of patients treated with artemether-lumefantrine.

Journal: The American journal of tropical medicine and hygiene 20060201

Title: Effects of artemisinin, artemether, arteether on the pharmacokinetics of carbamazepine.

Journal: Pharmacology 20060101

Title: Successful treatment of Plasmodium falciparum malaria with a six-dose regimen of artemether-lumefantrine versus quinine-doxycycline in the Western Amazon region of Brazil.

Journal: The American journal of tropical medicine and hygiene 20060101

Title: The efficacies of artesunate-sulfadoxine-pyrimethamine and artemether-lumefantrine in the treatment of uncomplicated, Plasmodium falciparum malaria, in an area of low transmission in central Sudan.

Journal: Annals of tropical medicine and parasitology 20060101

Title: Intramuscular artemether in the treatment of uncomplicated Plasmodium falciparum malaria in Sudanese patients.

Journal: Saudi medical journal 20060101

Title: Artemether-lumefantrine versus artesunate plus amodiaquine for treating uncomplicated childhood malaria in Nigeria: randomized controlled trial.

Journal: Malaria journal 20060101

Title: Some pregnancy-related effects of artemether in laboratory animals.

Journal: Pharmacology 20060101

Title: Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda.

Journal: Malaria journal 20060101

Title: From chloroquine to artemisinin-based combination therapy: the Sudanese experience.

Journal: Malaria journal 20060101

Title: Safety and efficacy of lumefantrine-artemether (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Zambian adults.

Journal: Malaria journal 20060101

Title: Assessment of the therapeutic efficacy of a paediatric formulation of artemether-lumefantrine (Coartesiane) for the treatment of uncomplicated Plasmodium falciparum in children in Zambia.

Journal: Malaria journal 20060101

Title: Malaria treatment failures after artemisinin-based therapy in three expatriates: could improved manufacturer information help to decrease the risk of treatment failure?

Journal: Malaria journal 20060101

Title: Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo.

Journal: Malaria journal 20060101

Title: Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6.

Journal: Lancet (London, England) 20051203

Title: Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa.

Journal: PLoS medicine 20051101

Title: Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051015

Title: Efficacy of chloroquine + sulfadoxine--pyrimethamine, mefloquine + artesunate and artemether + lumefantrine combination therapies to treat Plasmodium falciparum malaria in the Chittagong Hill Tracts, Bangladesh.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20051001

Title: Coartem (artemether-lumefantrine) in Africa: the beginning of the end?

Journal: The Journal of infectious diseases 20051001

Title: Pegylated lysine based copolymeric dendritic micelles for solubilization and delivery of artemether.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050902

Title: Towards control of schistosomiasis in sub-Saharan Africa.

Journal: Journal of helminthology 20050901

Title: Antifungal activity of artemisinin derivatives.

Journal: Journal of natural products 20050801

Title: Safety and efficacy of artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in Ethiopia.

Journal: East African medical journal 20050801

Title: Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes.

Journal: Journal of medicinal chemistry 20050728

Title: Synthesis and immunosuppressive activity of new artemisinin derivatives. 1. [12(beta or alpha)-Dihydroartemisininoxy]phen(ox)yl aliphatic acids and esters.

Journal: Journal of medicinal chemistry 20050714

Title: Blackwater fever in children, Burundi.

Journal: Emerging infectious diseases 20050701

Title: Malaria: uncomplicated, caused by Plasmodium falciparum.

Journal: Clinical evidence 20050601

Title: Towards a proteomic definition of CoArtem action in Plasmodium falciparum malaria.

Journal: Proteomics 20050501

Title: Antimalarial drugs: QT prolongation and cardiac arrhythmias.

Journal: Expert opinion on drug safety 20050501

Title: Convenient access both to highly antimalaria-active 10-arylaminoartemisinins, and to 10-alkyl ethers including artemether, arteether, and artelinate.

Journal: Chembiochem : a European journal of chemical biology 20050401

Title: Supervised versus unsupervised intake of six-dose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial.

Journal: Lancet (London, England) 20050401

Title: Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial.

Journal: Lancet (London, England) 20050401

Title: In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

Journal: The Journal of infectious diseases 20050315

Title: Treating severe malaria.

Journal: BMJ (Clinical research ed.) 20050212

Title: Rectal artemether versus intravenous quinine for the treatment of cerebral malaria in children in Uganda: randomised clinical trial.

Journal: BMJ (Clinical research ed.) 20050212

Title: Artemether as adjuvant therapy to praziquantel in murine Egyptian schistosomiasis mansoni.

Journal: The Journal of parasitology 20050201

Title: [Effects of combined artemether and dihydroarteamisinin in treatment of children with falciparum malaria].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20050101

Title: Pharmacodynamic analysis of antimalarials used in Plasmodium falciparum imported malaria in northern Italy.

Journal: Journal of travel medicine 20050101

Title: A double-blind field trial on the effects of artemether on Schistosoma japonicum infection in a highly endemic focus in southern China.

Journal: Acta tropica 20050101

Title: Development of antischistosomal drugs in China, with particular consideration to praziquantel and the artemisinins.

Journal: Acta tropica 20050101

Title: A randomized trial of artemether-lumefantrine versus mefloquine-artesunate for the treatment of uncomplicated multi-drug resistant Plasmodium falciparum on the western border of Thailand.

Journal: Malaria journal 20050101

Title: Artemether: a new therapeutic strategy in experimental rheumatoid arthritis.

Journal: Immunopharmacology and immunotoxicology 20050101

Title: Triggering of high-level resistance against Schistosoma mansoni reinfection by artemether in the mouse model.

Journal: The American journal of tropical medicine and hygiene 20041201

Title: Malaria: severe, life threatening.

Journal: Clinical evidence 20041201

Title: Effect of artemether alone and in combination with grapefruit juice on hepatic drug-metabolising enzymes and biochemical aspects in experimental Schistosoma mansoni.

Journal: International journal for parasitology 20041101

Title: Therapeutic efficacy of artemether-lumefantrine and artesunate-mefloquine for treatment of uncomplicated Plasmodium falciparum malaria in Luang Namtha Province, Lao People's Democratic Republic.

Journal: Tropical medicine & international health : TM & IH 20041101

Title: Adherence to a six-dose regimen of artemether-lumefantrine for treatment of uncomplicated Plasmodium falciparum malaria in Uganda.

Journal: The American journal of tropical medicine and hygiene 20041101

Title: Randomized comparison of chloroquine plus sulfadoxine-pyrimethamine versus artesunate plus mefloquine versus artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in the Lao People's Democratic Republic.

Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041015

Title: Artemether in the treatment of falciparum malaria during pregnancy in eastern Sudan.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20040901

Title: Adherence to a combination of artemether and lumefantrine (Coartem) in Kajo Keji, southern Sudan.

Journal: Annals of tropical medicine and parasitology 20040901

Title: Bayesian age-stage modelling of Plasmodium falciparum sequestered parasite loads in severe malaria patients.

Journal: Parasitology 20040901

Title: Efficacy of artemether-lumefantrine treatment in patients with acute uncomplicated Falciparum malaria in Mayotte, a French collectivity of the Comoros Archipelago.

Journal: Parasite (Paris, France) 20040901

Title: A randomized, comparative study of two regimens of beta-artemether for the treatment of uncomplicated, Plasmodium falciparum malaria, in northern Ghana.

Journal: Annals of tropical medicine and parasitology 20040701

Title: [Malaria: prophylaxis, treatment, stand-by medication. A single mosquito bite suffices].

Journal: MMW Fortschritte der Medizin 20040617

Title: [Efficacy of therapeutic combinations with artemisinin derivatives in the treatment of non complicated malaria in Burundi].

Journal: Tropical medicine & international health : TM & IH 20040601

Title: [Combined antimalarial therapy using artemisinin].

Journal: Parassitologia 20040601

Title: Effect of artemether on Schistosoma mansoni: dose-efficacy relationship, and changes in worm morphology and histopathology.

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20040601

Title: [Additive therapeutic effect of a combination of artemether and daphnetin against Plasmodium berghei in mice].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20040601

Title: Malaria: severe, life threatening.

Journal: Clinical evidence 20040601

Title: Fluoroartemisinin: trifluoromethyl analogues of artemether and artesunate.

Journal: Journal of medicinal chemistry 20040506

Title: Artemether in children with severe Malaria.

Journal: Indian pediatrics 20040501

Title: Design of a dissolution system for the evaluation of the release rate characteristics of artemether and dihydroartemisinin from tablets.

Journal: International journal of pharmaceutics 20040415

Title: Coartemether (artemether and lumefantrine): an oral antimalarial drug.

Journal: Expert review of anti-infective therapy 20040401

Title: Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin.

Journal: Journal of medicinal chemistry 20040311

Title: Selection and reversal of Plasmodium berghei resistance in the mouse model following repeated high doses of artemether.

Journal: Parasitology research 20040201

Title: Population pharmacokinetics of artemether and dihydroartemisinin following single intramuscular dosing of artemether in African children with severe falciparum malaria.

Journal: British journal of clinical pharmacology 20040201

Title: [Antischistosomal activity of artemether in experimental Schistosomiasis mansoni].

Journal: Revista de saude publica 20040201

Title: Laboratory evaluation of the ict malaria P.f./P.v. immunochromatographic test for detecting the panmalarial antigen using a rodent malaria model.

Journal: The American journal of tropical medicine and hygiene 20040201

Title: Artemether-lumefantrine for uncomplicated malaria: a systematic review.

Journal: Tropical medicine & international health : TM & IH 20040201

Title: Preparation of 10-trifluoromethyl artemether and artesunate. Influence of hexafluoropropan-2-ol on substitution reaction.

Journal: The Journal of organic chemistry 20031212

Title: A comparative clinical trial of artemether and quinine in children with severe malaria.

Journal: Indian pediatrics 20031001

Title: Monitoring the therapeutic efficacy of antimalarials against uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030901

Title: Neuropathological assessment of artemether-treated severe malaria.

Journal: Lancet (London, England) 20030726

Title: [Systematic review of benefits and harms of artemisinin-type compounds for preventing schistosomiasis].

Journal: Zhonghua yi xue za zhi 20030725

Title: Recent studies have reported significant toxicity of artemisinin and its derivatives for schistosomula in various Schistosoma species.

Journal: The American journal of tropical medicine and hygiene 20030701

Title: 1,4-Dihydroxy-2,3-dioxatricyclo[8.4.0.0(4,9)]tetradecane and derivatives with in vitro activity against Plasmodium falciparum, Trypanasoma b brucei, Trypanasoma cruzi, and Leishmaniasis infantum.

Journal: Bioorganic & medicinal chemistry letters 20030616

Title: A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides.

Journal: Journal of medicinal chemistry 20030605

Title: Comparative clinical trial of two-fixed combinations dihydroartemisinin-napthoquine-trimethoprim (DNP) and artemether-lumefantrine (Coartem/Riamet) in the treatment of acute uncomplicated falciparum malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030601

Title: Malaria in endemic areas.

Journal: Clinical evidence 20030601

Title: Study on the mechanism of action of artemether against schistosomes: the identification of cysteine adducts of both carbon-centred free radicals derived from artemether.

Journal: Bioorganic & medicinal chemistry letters 20030519

Title: Schistosoma japonicum: In vitro effects of artemether combined with haemin depend on cultivation media and appraisal of artemether products appearing in the media.

Journal: Parasitology research 20030401

Title: The new drug combinations: their place in the treatment of uncomplicated Plasmodium falciparum malaria.

Journal: Fundamental & clinical pharmacology 20030401

Title: Alkylation of manganese(II) tetraphenylporphyrin by antimalarial fluorinated artemisinin derivatives.

Journal: Bioorganic & medicinal chemistry letters 20030324

Title: The management of severe falciparum malaria.

Journal: American journal of respiratory and critical care medicine 20030301

Title: Clinical experience with intravenous quinine, intramuscular artemether and intravenous artesunate for the treatment of severe malaria in Thailand.

Journal: The Southeast Asian journal of tropical medicine and public health 20030301

Title: [Three newly registered drugs in the Netherlands for the treatment and chemoprophylaxis of malaria: atovaquone-proguanil, artemether-lumefantrine and artemotil].

Journal: Nederlands tijdschrift voor geneeskunde 20030215

Title: Presumptive artemether resistance in a patient with mixed malarial infection.

Journal: The Journal of the Association of Physicians of India 20030201

Title: Synthesis and antimalarial activity of 2-methoxyprop-2-yl peroxides derivatives.

Journal: Bioorganic & medicinal chemistry letters 20030106

Title: Randomized, double-blind, placebo-controlled trial of oral artemether for the prevention of patent Schistosoma haematobium infections.

Journal: The American journal of tropical medicine and hygiene 20030101

Title: [An imported case of falciparum malaria successfully treated with Artemether-Lumefantrine in Japan].

Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20030101

Title: Artemether-lumefantrine for treating uncomplicated falciparum malaria.

Journal: The Cochrane database of systematic reviews 20030101

Title: [Drug resistant tropical malaria in the Republic of Guinea (West Africa)].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20030101

Title: Suspected allergy to artemether-lumefantrine treatment of malaria.

Journal: Journal of travel medicine 20030101

Title: [Effect of mitochondrial membrane potential in the neurotoxicity of artemether].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20030101

Title: [Early treatment of Toxoplasma gondii infections with artemether in mice].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20030101

Title: Case report: combination artemether-lumefantrine and haemolytic anaemia following a malarial attack.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20030101

Title: Artemesinins for severe malaria in Africa?

Journal: East African medical journal 20021201

Title: Comparison of intramuscular artemether and intravenous quinine in the treatment of Sudanese children with severe falciparum malaria.

Journal: East African medical journal 20021201

Title: Interaction trial between artemether-lumefantrine (Riamet) and quinine in healthy subjects.

Journal: Journal of clinical pharmacology 20021001

Title: Schistosomiasis.

Journal: The New England journal of medicine 20020905

Title: Schistosoma japonicum: effect of artemether on glutathione S-transferase and superoxide dismutase.

Journal: Experimental parasitology 20020901

Title: mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether.

Journal: Biochemical pharmacology 20020815

Title: The efficacy of artemether versus quinine in the treatment of cerebral malaria.

Journal: Journal of the Egyptian Society of Parasitology 20020801

Title: Development and validation of a high-performance liquid chromatography-mass spectrometry assay for the determination of artemether and its metabolite dihydroartemisinin in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020715

Title: Ultrastructural alterations in adult Schistosoma mansoni caused by artemether.

Journal: Memorias do Instituto Oswaldo Cruz 20020701

Title: Malaria in endemic areas.

Journal: Clinical evidence 20020601

Title: Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria.

Journal: British journal of clinical pharmacology 20020501

Title: Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia.

Journal: Acta tropica 20020501

Title: Neurotoxicity and efficacy of arteether related to its exposure times and exposure levels in rodents.

Journal: The American journal of tropical medicine and hygiene 20020501

Title: Schistosomiasis.

Journal: The New England journal of medicine 20020418

Title: Preparation of beta-artemether liposomes, their HPLC-UV evaluation and relevance for clearing recrudescent parasitaemia in Plasmodium chabaudi malaria-infected mice.

Journal: Journal of pharmaceutical and biomedical analysis 20020401

Title: Chemotherapeutic failures in Plasmodium falciparum infections.

Journal: Tropical doctor 20020401

Title: The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria.

Journal: The Journal of infectious diseases 20020301

Title: Mechanism-based design of parasite-targeted artemisinin derivatives: synthesis and antimalarial activity of new diamine containing analogues.

Journal: Journal of medicinal chemistry 20020227

Title: Transmission electron microscopic observations on ultrastructural damage in juvenile Schistosoma mansoni caused by artemether.

Journal: Acta tropica 20020101

Title: Potential long-term toxicity of repeated orally administered doses of artemether in rats.

Journal: The American journal of tropical medicine and hygiene 20020101

Title: Comparative study of the effects of artemether and artesunate on juvenile and adult Schistosoma mansoni in experimentally infected mice.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Title: [Efficacy of mefloquine, halofantrine, and coarteme in the treatment of tropical malaria].

Journal: Meditsinskaia parazitologiia i parazitarnye bolezni 20020101

Title: In vitro antimicrobial interactions of arthemeter with some 4-quinolones.

Journal: Bollettino chimico farmaceutico 20020101

Title: [Pharmacokinetic studies on artemether under conditions simulated in vivo].

Journal: Se pu = Chinese journal of chromatography 20020101

Title: Glutathione inhibits the antischistosomal activity of artemether.

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20020101

Title: [Riamet: a new antimalarial for curative treatment of malaria].

Journal: Medecine tropicale : revue du Corps de sante colonial 20020101

Title: The potential of artemether for the control of schistosomiasis.

Journal: International journal for parasitology 20011201

Title: A comparison of oral artesunate and artemether antimalarial bioactivities in acute falciparum malaria.

Journal: British journal of clinical pharmacology 20011201

Title: Authentication of artemether, artesunate and dihydroartemisinin antimalarial tablets using a simple colorimetric method.

Journal: Tropical medicine & international health : TM & IH 20011201

Title: Current progress in the development and use of artemether for chemoprophylaxis of major human schistosome parasites.

Journal: Current medicinal chemistry 20011201

Title: Blackwater fever treated with artemether.

Journal: The Journal of the Association of Physicians of India 20011201

Title: A comparison of the stage-specific efficacy of chloroquine, artemether and dioncophylline B against the rodent malaria parasite Plasmodium chabaudi chabaudi in vivo.

Journal: Parasitology research 20011001

Title: Ammunition against malaria.

Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010904

Title: Effect of combined treatment with praziquantel and artemether on Schistosoma japonicum and Schistosoma mansoni in experimentally infected animals.

Journal: Acta tropica 20010901

Title: Tegumental alterations in juvenile Schistosoma haematobium harboured in hamsters following artemether treatment.

Journal: Parasitology international 20010901

Title: Potent antimalarial activities of polyether antibiotic, X-206.

Journal: The Journal of antibiotics 20010801

Title: Artemether vs quinine therapy in Plasmodium falciparum malaria in Manipur--a preliminary report.

Journal: The Journal of communicable diseases 20010601

Title: Histopathological changes in juvenile Schistosoma haematobium harboured in hamsters treated with artemether.

Journal: Acta tropica 20010525

Title: Madagascan isolates of Plasmodium falciparum showing low sensitivity to artemether in vitro.

Journal: Annals of tropical medicine and parasitology 20010401

Title: The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro.

Journal: Biochemical pharmacology 20010215

Title: Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin.

Journal: Journal of medicinal chemistry 20010104

Title: Artemether administered together with haemin damages schistosomes in vitro.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: A clinical and pharmacokinetic trial of six doses of artemether-lumefantrine for multidrug-resistant Plasmodium falciparum malaria in Thailand.

Journal: The American journal of tropical medicine and hygiene 20010101

Title: [Malaria].

Journal: Ryoikibetsu shokogun shirizu 20010101

Title: A meta-analysis using individual patient data of trials comparing artemether with quinine in the treatment of severe falciparum malaria.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 20010101

Title: A randomized controlled trial comparing artemether and quinine in the treatment of cerebral malaria in Bangladesh.

Journal: Indian journal of malariology 20010101

Title: [A study of artemether combined with primaquine in the treatment of falciparum malaria].

Journal: Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20010101

Title: Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether.

Journal: Journal of medicinal chemistry 19991230

Title: Population pharmacokinetics and therapeutic response of CGP 56697 (artemether + benflumetol) in malaria patients.

Journal: British journal of clinical pharmacology 19981201

Title: Effect of artemether on electrocardiogram in severe falciparum malaria.

Journal: The Southeast Asian journal of tropical medicine and public health 19970901

Title: Extraction of artemisinin and artemisinic acid: preparation of artemether and new analogues.

Journal: Transactions of the Royal Society of Tropical Medicine and Hygiene 19940601

Title: Comparison of beta-artemether and beta-arteether against malaria parasites in vitro and in vivo.

Journal: The American journal of tropical medicine and hygiene 19930301

Title: Inhibition of growth of Toxoplasma gondii by qinghaosu and derivatives.

Journal: Antimicrobial agents and chemotherapy 19901001

Title: Xiao, S., et al., Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia. Acta Trop, 2002. 82(2): p. 175-81.

Title: Wu, Z.P., et al., Inhibitive effect of artemether on tumor growth and angiogenesis in the rat C6 orthotopic brain gliomas model. Integr Cancer Ther, 2009. 8(1): p. 88-92.

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Tags:71963-77-4 Molecular Formula|71963-77-4 MDL|71963-77-4 SMILES|71963-77-4 Artemether