Title: Antifibrinolytic agents reduce blood loss during pediatric vertebral column resection procedures.
Journal: Spine 20121101
Title: A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use.
Journal: Pediatric surgery international 20121101
Title: CCAAT/enhancer binding protein-α regulates the protease/antiprotease balance required for bronchiolar epithelium regeneration.
Journal: American journal of respiratory cell and molecular biology 20121001
Title: Mechanisms underlying the augmentation of phenylbiguanide and capsaicin induced cardiorespiratory reflexes by Mesobuthus tamulus venom.
Journal: Pulmonary pharmacology & therapeutics 20121001
Title: Wanted and wanting: antibody against methionine sulfoxide.
Journal: Free radical biology & medicine 20120915
Title: Activity and inhibition of prostasin and matriptase on apical and basolateral surfaces of human airway epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20120715
Title: Comparative evaluation of the effects of tranexamic acid and low-dose aprotinin on post-valvular heart surgery bleeding and allogenic transfusion.
Journal: Interactive cardiovascular and thoracic surgery 20120701
Title: Lung amyloid nodule detected by 99mTc-aprotinin scintigraphy.
Journal: Annals of nuclear medicine 20120701
Title: Application of metal-coded affinity tags (MeCAT): absolute protein quantification with top-down and bottom-up workflows by metal-coded tagging.
Journal: Analytical chemistry 20120619
Title: Comparison of aprotinin and tranexamic acid in adult scoliosis correction surgery.
Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20120601
Title: PTX3 controls activation of matrix metalloproteinase 1 and apoptosis in conjunctivochalasis fibroblasts.
Journal: Investigative ophthalmology & visual science 20120601
Title: Tri-domain bifunctional inhibitor of metallocarboxypeptidases A and serine proteases isolated from marine annelid Sabellastarte magnifica.
Journal: The Journal of biological chemistry 20120504
Title: Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery.
Journal: The Journal of thoracic and cardiovascular surgery 20120501
Title: Doxycycline indirectly inhibits proteolytic activation of tryptic kallikrein-related peptidases and activation of cathelicidin.
Journal: The Journal of investigative dermatology 20120501
Title: Clinical evaluation of leukocyte filtration as an alternative anti-inflammatory strategy to aprotinin in high-risk patients undergoing coronary revascularization.
Journal: Surgery today 20120401
Title: Comparative analysis of antifibrinolytic medications in pediatric heart surgery.
Journal: The Journal of thoracic and cardiovascular surgery 20120301
Title: Is tranexamic acid really an alternative to aprotinin?
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20120201
Title: Risk factors for re-exploration due to bleeding after coronary artery bypass grafting.
Journal: Scandinavian cardiovascular journal : SCJ 20120201
Title: The frequency of thrombotic events among adults given antifibrinolytic drugs for spontaneous bleeding: systematic review and meta-analysis of observational studies and randomized trials.
Journal: Current drug safety 20120201
Title: Acute renal failure following lung transplantation: risk factors, mortality, and long-term consequences.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20120101
Title: Longistatin is an unconventional serine protease and induces protective immunity against tick infestation.
Journal: Molecular and biochemical parasitology 20120101
Title: Evolution, expansion and expression of the Kunitz/BPTI gene family associated with long-term blood feeding in Ixodes Scapularis.
Journal: BMC evolutionary biology 20120101
Title: [Capillary ENT hemangioma].
Journal: Vestnik otorinolaringologii 20120101
Title: Risks of harms using antifibrinolytics in cardiac surgery: systematic review and network meta-analysis of randomised and observational studies.
Journal: BMJ (Clinical research ed.) 20120101
Title: The effect of antifibrinolytic prophylaxis on postoperative outcomes in patients undergoing cardiac operations.
Journal: International surgery 20120101
Title: Methods to decrease blood loss and transfusion requirements for liver transplantation.
Journal: The Cochrane database of systematic reviews 20111207
Title: Switch from aprotinin to ε-aminocaproic acid: impact on blood loss, transfusion, and clinical outcome in neonates undergoing cardiac surgery.
Journal: British journal of anaesthesia 20111201
Title: Serum osteocalcin levels in patients with nonalcoholic fatty liver disease: association with ballooning degeneration.
Journal: Scandinavian journal of clinical and laboratory investigation 20111201
Title: The P(2)' residue is a key determinant of mesotrypsin specificity: engineering a high-affinity inhibitor with anticancer activity.
Journal: The Biochemical journal 20111115
Title: Tailoring small proteins towards biomedical applications.
Journal: Current pharmaceutical biotechnology 20111101
Title: Recombinant expression of ShPI-1A, a non-specific BPTI-Kunitz-type inhibitor, and its protection effect on proteolytic degradation of recombinant human miniproinsulin expressed in Pichia pastoris.
Journal: FEMS yeast research 20111101
Title: Plasmin substrate binding site cooperativity guides the design of potent peptide aldehyde inhibitors.
Journal: Biochemistry 20111004
Title: The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity.
Journal: Investigational new drugs 20111001
Title: The thylakoid protease Deg2 is involved in stress-related degradation of the photosystem II light-harvesting protein Lhcb6 in Arabidopsis thaliana.
Journal: The New phytologist 20111001
Title: Aprotinin and similar protease inhibitors as drugs against influenza.
Journal: Antiviral research 20111001
Title: Targeted long-term venous occlusion using pulsed high-intensity focused ultrasound combined with a pro-inflammatory agent.
Journal: Ultrasound in medicine & biology 20111001
Title: Conformational changes of the chaperone SecB upon binding to a model substrate--bovine pancreatic trypsin inhibitor (BPTI).
Journal: Biological chemistry 20111001
Title: Early postoperative outcomes and blood product utilization in adult cardiac surgery: the post-aprotinin era.
Journal: Circulation 20110913
Title: The role of factor XIa (FXIa) catalytic domain exosite residues in substrate catalysis and inhibition by the Kunitz protease inhibitor domain of protease nexin 2.
Journal: The Journal of biological chemistry 20110909
Title: Bleeding and management of coagulopathy.
Journal: The Journal of thoracic and cardiovascular surgery 20110901
Title: Role of TGF-β1 and TNF-α in IL-1β mediated activation of proMMP-9 in pulmonary artery smooth muscle cells: involvement of an aprotinin sensitive protease.
Journal: Archives of biochemistry and biophysics 20110901
Title: Efficacy and safety of aprotinin in neonatal congenital heart operations.
Journal: The Annals of thoracic surgery 20110901
Title: Activation of pro-uPA is critical for initial escape from the primary tumor and hematogenous dissemination of human carcinoma cells.
Journal: Neoplasia (New York, N.Y.) 20110901
Title: Population pharmacokinetic analysis and dosing regimen optimization of aprotinin in neonates and young infants undergoing cardiopulmonary bypass.
Journal: Journal of clinical pharmacology 20110801
Title: Free energy of contact formation in proteins: efficient computation in the elastic network approximation.
Journal: Physical review. E, Statistical, nonlinear, and soft matter physics 20110701
Title: Aprotinin versus tranexamic acid during liver transplantation: impact on blood product requirements and survival.
Journal: Transplantation 20110615
Title: A comparison of the effect of aprotinin and ε-aminocaproic acid on renal function in children undergoing cardiac surgery.
Journal: Journal of cardiothoracic and vascular anesthesia 20110601
Title: Detection of trace proteins in multicomponent mixtures using displacement chromatography.
Journal: Analytical chemistry 20110601
Title: Kallikrein-kinin system: a surgical perspective in post-aprotinin era.
Journal: The Journal of surgical research 20110501
Title: Tranexamic acid: an alternative to aprotinin as antifibrinolytic therapy in pediatric congenital heart surgery.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20110401
Title: Continuous localized monitoring of plasmin activity identifies differential and regional effects of the serine protease inhibitor aprotinin: relevance to antifibrinolytic therapy.
Journal: Journal of cardiovascular pharmacology 20110401
Title: Aprotinin, a protease inhibitor, suppresses proteolytic activation of pandemic H1N1v influenza virus.
Journal: Antiviral chemistry & chemotherapy 20110307
Title: Aprotinin, but not tranexamic acid, is associated with increased pulmonary microvascular fibrin deposition after cardiac surgery.
Journal: Thrombosis research 20110301
Title: [Transfusion requirements, morbidity and mortality in cardiac surgery and the use of antifibrinolytic agents: a comparison of aprotinin and tranexamic acid].
Journal: Revista espanola de anestesiologia y reanimacion 20110301
Title: Quantitative assay for bradykinin in rat plasma by liquid chromatography coupled to tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20110220
Title: Up-regulation of ectopic trypsins in the myocardium by influenza A virus infection triggers acute myocarditis.
Journal: Cardiovascular research 20110215
Title: Engineering kunitz domain 1 (KD1) of human tissue factor pathway inhibitor-2 to selectively inhibit fibrinolysis: properties of KD1-L17R variant.
Journal: The Journal of biological chemistry 20110211
Title: ε-Aminocaproic acid and clinical value in cardiac anesthesia.
Journal: Journal of cardiothoracic and vascular anesthesia 20110201
Title: Removal of aprotinin from low-dose aprotinin/tranexamic acid antifibrinolytic therapy increases transfusion requirements in cardiothoracic surgery.
Journal: Interactive cardiovascular and thoracic surgery 20110201
Title: The post-BART anti-fibrinolytic dilemma?
Journal: Journal of cardiothoracic and vascular anesthesia 20110201
Title: Conference discussion: Removal of aprotinin from low-dose aprotinin/tranexamic acid antifibrinolytic therapy increases transfusion requirements in cardiothoracic surgery.
Journal: Interactive cardiovascular and thoracic surgery 20110201
Title: Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Journal: The Cochrane database of systematic reviews 20110119
Title: Antifibrinolytic drugs for acute traumatic injury.
Journal: The Cochrane database of systematic reviews 20110119
Title: A randomized, placebo-controlled trial of aprotinin to reduce primary graft dysfunction following lung transplantation.
Journal: Clinical transplantation 20110101
Title: Distinct folding pathways of two homologous disulfide proteins: bovine pancreatic trypsin inhibitor and tick anticoagulant peptide.
Journal: Antioxidants & redox signaling 20110101
Title: Maggot chymotrypsin I from Lucilia sericata is resistant to endogenous wound protease inhibitors.
Journal: The British journal of dermatology 20110101
Title: Blood conservation strategies for reducing peri-operative blood loss in open heart surgery.
Journal: Mymensingh medical journal : MMJ 20110101
Title: Aprotinin and classic wound drainage are unnecessary in total hip replacement - a prospective randomized trial.
Journal: European journal of medical research 20110101
Title: Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature.
Journal: PloS one 20110101
Title: Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Journal: The Cochrane database of systematic reviews 20110101
Title: Investigation of a potential scintigraphic tracer for imaging apoptosis: radioiodinated annexin V-Kunitz protease inhibitor fusion protein.
Journal: Journal of biomedicine & biotechnology 20110101
Title: [Aprotinin-induced inhibition of pandemic influenza virus A(H1N1) reproduction].
Journal: Voprosy virusologii 20110101
Title: A randomized trial of aprotinin-free fibrin sealant versus absorbable hemostat.
Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20110101
Title: Impact of aprotinin and renal function on mortality: a retrospective single center analysis.
Journal: Journal of cardiothoracic surgery 20110101
Title: Three genes expressing Kunitz domains in the epididymis are related to genes of WFDC-type protease inhibitors and semen coagulum proteins in spite of lacking similarity between their protein products.
Journal: BMC biochemistry 20110101
Title: [Role of the kallikrein kinin system and its interrelationship with vasoactive systems in pregnancy].
Journal: Medicina 20110101
Title: Acute regulation of the epithelial sodium channel in airway epithelia by proteases and trafficking.
Journal: American journal of respiratory cell and molecular biology 20101201
Title: Changing from aprotinin to tranexamic acid results in increased use of blood products and recombinant factor VIIa for aortic surgery requiring hypothermic arrest.
Journal: Journal of cardiothoracic and vascular anesthesia 20101201
Title: Apical serine protease activity is necessary for assembly of a high-resistance renal collecting duct epithelium.
Journal: Acta physiologica (Oxford, England) 20101201
Title: Sevoflurane-induced preconditioning: impact of protocol and aprotinin administration on infarct size and endothelial nitric-oxide synthase phosphorylation in the rat heart in vivo.
Journal: Anesthesiology 20101201
Title: Blood conservation in cardiac surgery.
Journal: Journal of perioperative practice 20101201
Title: Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109.
Journal: Breast cancer research and treatment 20101101
Title: TGF-β signaling in gingival fibroblast-epithelial interaction.
Journal: Journal of dental research 20101101
Title: Safety and efficacy of aprotinin and tranexamic acid in pulmonary endarterectomy surgery with hypothermia: review of 200 patients.
Journal: The Annals of thoracic surgery 20101101
Title: Mechanisms and specificity of factor XIa and trypsin inhibition by protease nexin 2 and basic pancreatic trypsin inhibitor.
Journal: Journal of biochemistry 20101001
Title: Calculations of the binding affinities of protein-protein complexes with the fast multipole method.
Journal: The Journal of chemical physics 20100907
Title: Urokinase down-regulation by aprotinin in rabbit corneal cells after photorefractive keratectomy.
Journal: Current eye research 20100901
Title: A single dose of aprotinin prevents platelet hyporeactivity after coronary artery bypass graft surgery.
Journal: Polskie Archiwum Medycyny Wewnetrznej 20100901
Title: Long-term prognostic value of analysis of sympathetic drive by myocardial 123I-metaiodobenzylganidine scintigraphy in chronic heart failure.
Journal: Chinese medical journal 20100805
Title: Interleukin-6 stimulates epithelial sodium channels in mouse cortical collecting duct cells.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100801
Title: Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding.
Journal: Biochemical and biophysical research communications 20100702
Title: Aprotinin combined with nitric oxide and prostaglandin E1 protects the canine kidney from cardiopulmonary bypass-induced injury.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20100701
Title: Protein content of molar-incisor hypomineralisation enamel.
Journal: Journal of dentistry 20100701
Title: Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway.
Journal: Biological chemistry 20100701
Title: Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass.
Journal: Anesthesia and analgesia 20100701
Title: Perioperative anaphylaxis.
Journal: The Medical clinics of North America 20100701
Title: Blood hibernation: a novel strategy to inhibit systemic inflammation and coagulation induced by cardiopulmonary bypass.
Journal: Chinese medical journal 20100701
Title: The effect of the suspension of the license for aprotinin on the care of patients undergoing cardiac surgery: a survey of cardiac anesthesiologists' and surgeons' opinions in the United Kingdom.
Journal: Journal of cardiothoracic and vascular anesthesia 20100601
Title: Lessons from aprotinin: is the routine use and inconsistent dosing of tranexamic acid prudent? Meta-analysis of randomised and large matched observational studies.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20100601
Title: Effects of aprotinin or tranexamic acid on proteolytic/cytokine profiles in infants after cardiac surgery.
Journal: The Annals of thoracic surgery 20100601
Title: ENaC-mediated effects assessed by MRI in a rat model of hypertonic saline-induced lung hydration.
Journal: British journal of pharmacology 20100601
Title: 2010 Young Investigator Award winner: Therapeutic aprotinin stimulates osteoblast proliferation but inhibits differentiation and bone matrix mineralization.
Journal: Spine 20100420
Title: Low postoperative dose of aprotinin reduces bleeding and is safe in patients receiving clopidogrel before coronary artery bypass surgery. A prospective randomized study.
Journal: Interactive cardiovascular and thoracic surgery 20100401
Title: Genetic transformation and pyramiding of aprotinin-expressing sugarcane with cry1Ab for shoot borer (Chilo infuscatellus) resistance.
Journal: Plant cell reports 20100401
Title: Neoplastic progression of the human breast cancer cell line G3S1 is associated with elevation of cytoskeletal dynamics and upregulation of MT1-MMP.
Journal: International journal of oncology 20100401
Title: Modulation of an active-site cysteine pKa allows PDI to act as a catalyst of both disulfide bond formation and isomerization.
Journal: Journal of molecular biology 20100305
Title: Identification of a novel set of scaffolding residues that are instrumental for the inhibitory property of Kunitz (STI) inhibitors.
Journal: Protein science : a publication of the Protein Society 20100301
Title: Antifibrinolytics in major orthopaedic surgery.
Journal: The Journal of the American Academy of Orthopaedic Surgeons 20100301
Title: Biochemical study and in vitro insect immune suppression by a trypsin-like secreted protease from the nematode Steinernema carpocapsae.
Journal: Parasite immunology 20100301
Title: Recombinant bovine pancreatic trypsin inhibitor protects the liver from carbon tetrachloride-induced acute injury in mice.
Journal: The Journal of pharmacy and pharmacology 20100301
Title: Biochemical characterization of a Kunitz type inhibitor similar to dendrotoxins produced by Rhipicephalus (Boophilus) microplus (Acari: Ixodidae) hemocytes.
Journal: Veterinary parasitology 20100210
Title: Safety and efficacy of tranexamic acid compared with aprotinin in thoracic aortic surgery with deep hypothermic circulatory arrest.
Journal: Journal of cardiothoracic and vascular anesthesia 20100201
Title: Aprotinin in lung transplantation is associated with an increased incidence of primary graft dysfunction.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20100201
Title: Hypersensitivity reactions to aprotinin re-exposure in paediatric surgery.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20100201
Title: Lessons from the aprotinin saga: current perspective on antifibrinolytic therapy in cardiac surgery.
Journal: Journal of anesthesia 20100201
Title: Can we safely reduce blood loss during lumbar pedicle subtraction osteotomy procedures using tranexamic acid or aprotinin? A comparative study with controls.
Journal: Spine 20100115
Title: The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery.
Journal: Anesthesia and analgesia 20100101
Title: Strategies to prevent intraoperative lung injury during cardiopulmonary bypass.
Journal: Journal of cardiothoracic surgery 20100101
Title: [Successful use of recombinant factor VIIa in the control of a massive bleeding in two patients with biventricular assist device (Thoratec)].
Journal: Annales francaises d'anesthesie et de reanimation 20100101
Title: Managing fibrinolysis without aprotinin.
Journal: The Annals of thoracic surgery 20100101
Title: Effects of novel synthetic serine protease inhibitors on postoperative blood loss, coagulation parameters, and vascular relaxation after cardiac surgery.
Journal: The Journal of thoracic and cardiovascular surgery 20100101
Title: Comparison of three dose regimens of aprotinin in infants undergoing the arterial switch operation.
Journal: Annals of cardiac anaesthesia 20100101
Title: Carboxymethyl-starch excipients for gastrointestinal stable oral protein formulations containing protease inhibitors.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101
Title: Assessment of aprotinin in the reduction of inflammatory systemic response in children undergoing surgery with cardiopulmonary bypass.
Journal: Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular 20100101
Title: Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis.
Journal: Critical care (London, England) 20100101
Title: Tranexamic acid in cardiac surgery: is there a cause for concern?
Journal: Critical care (London, England) 20100101
Title: The use of thromboelastometry in the assessment of hemostasis during orthotopic liver transplantation reduces the demand for blood products.
Journal: Annals of transplantation 20100101
Title: Serine protease inhibitors suppress pancreatic endogenous proteases and modulate bacterial neutral proteases.
Journal: Islets 20100101
Title: [Diagnosis and correction of thrombohemorrhagic complications in cardiosurgical patients in the early postoperative period].
Journal: Anesteziologiia i reanimatologiia 20100101
Title: Comparative effects of aprotinin and human recombinant R24K KD1 on temporal renal function in Long-Evans rats.
Journal: The Journal of pharmacology and experimental therapeutics 20091201
Title: Conservative treatment of Achilles tendinopathy: emerging techniques.
Journal: Foot and ankle clinics 20091201
Title: Aprotinin-associated risks in off-pump coronary artery bypass grafting.
Journal: The Thoracic and cardiovascular surgeon 20091201
Title: Tranexamic acid--an alternative to aprotinin in fibrin-based cardiovascular tissue engineering.
Journal: Tissue engineering. Part A 20091101
Title: Use of aprotinin in cardiac surgery: effectiveness and safety in a population-based study.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20091101
Title: Aprotinin in cardiac surgery patients: is the risk worth the benefit?
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20091101
Title: Aprotinin abolishes sevoflurane postconditioning by inhibiting nitric oxide production and phosphorylation of protein kinase C-delta and glycogen synthase kinase 3beta.
Journal: Anesthesiology 20091101
Title: A randomized clinical trial investigating the relationship between aprotinin and hypercoagulability in off-pump coronary surgery.
Journal: Anesthesia and analgesia 20091101
Title: Pharmacological interventions to decrease blood loss and blood transfusion requirements for liver resection.
Journal: The Cochrane database of systematic reviews 20091007
Title: Mortality manifesto: a meta-analysis of aprotinin and tranexamic acid mortality.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20091001
Title: A comparison before and after aprotinin was suspended in cardiac surgery: different results in the real world from a single cardiac center in China.
Journal: The Journal of thoracic and cardiovascular surgery 20091001
Title: Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury.
Journal: Toxicology 20090901
Title: RP-HPLC-ESI-MS characterization of novel peptide fragments related to rat parotid secretory protein in parasympathetic induced saliva.
Journal: Journal of separation science 20090901
Title: Tranexamic acid and aprotinin in low- and intermediate-risk cardiac surgery: a non-sponsored, double-blind, randomised, placebo-controlled trial.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090801
Title: Cell-controlled and spatially arrayed gene delivery from fibrin hydrogels.
Journal: Biomaterials 20090801
Title: Aprotinin reduces the antiplatelet effect of clopidogrel.
Journal: Interactive cardiovascular and thoracic surgery 20090801
Title: Pediatric pharmacology in the first year of life.
Journal: Current opinion in anaesthesiology 20090801
Title: Aprotinin increases mortality as compared with tranexamic acid in cardiac surgery: a meta-analysis of randomized head-to-head trials.
Journal: Interactive cardiovascular and thoracic surgery 20090701
Title: The effect of epsilon-aminocaproic acid and aprotinin on fibrinolysis and blood loss in patients undergoing primary, isolated coronary artery bypass surgery: a randomized, double-blind, placebo-controlled, noninferiority trial.
Journal: Anesthesia and analgesia 20090701
Title: The association of renal dysfunction and the use of aprotinin in patients undergoing congenital cardiac surgery requiring cardiopulmonary bypass.
Journal: Anesthesia and analgesia 20090701
Title: eComment: A comparison of the safety of aprotinin and tranexamic acid in cardiac surgery.
Journal: Interactive cardiovascular and thoracic surgery 20090701
Title: Effect of low-molecular weight trypsin inhibitor, nafamostat mesilate, on trypsin activity using the pancreatic acinar cells.
Journal: Pancreas 20090701
Title: Optimal dose of aprotinin for neuroprotection and renal function in a piglet survival model.
Journal: The Journal of thoracic and cardiovascular surgery 20090601
Title: Serine protease inhibitor aprotinin ameliorates renal injury in a rat model of ischemia-perfusion injury.
Journal: Transplantation proceedings 20090601
Title: Effect of topical aprotinin on early postoperative bleeding and ICU stay after coronary artery bypass graft surgeries.
Journal: Pakistan journal of biological sciences : PJBS 20090515
Title: Effects of early administration of dexamethasone, N-acetylcysteine and aprotinin on inflammatory and oxidant-antioxidant status after lung contusion in rats.
Journal: Injury 20090501
Title: Living without aprotinin: the results of a 5-year blood saving program in cardiac surgery.
Journal: Acta anaesthesiologica Scandinavica 20090501
Title: Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.
Journal: Protein science : a publication of the Protein Society 20090501
Title: Physico-chemical and antifungal properties of protease inhibitors from Acacia plumosa.
Journal: Phytochemistry 20090501
Title: PAI-1 gene: pharmacogenetic association of 4G/4G genotype with bleeding after cardiac surgery--pilot study.
Journal: European journal of anaesthesiology 20090501
Title: Nuclear imaging in cardiac amyloidosis.
Journal: European journal of nuclear medicine and molecular imaging 20090401
Title: Textilinin-1, an alternative anti-bleeding agent to aprotinin: Importance of plasmin inhibition in controlling blood loss.
Journal: British journal of haematology 20090401
Title: [Information needed to specify a protein structure: structure and thermodynamics of a highly simplified bovine pancreatic trypsin inhibitor].
Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20090401
Title: Coagulation assessment by rotation thrombelastometry in normal pregnancy.
Journal: Thrombosis and haemostasis 20090401
Title: The comparison of parathyroid hormone degradation effect by various protease inhibitors in blood specimen.
Journal: The Korean journal of laboratory medicine 20090401
Title: Multivariate frequency domain analysis of protein dynamics.
Journal: The Journal of chemical physics 20090328
Title: The effect of aprotinin, tranexamic acid, and aminocaproic acid on blood loss and use of blood products in major pediatric surgery: a meta-analysis.
Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20090301
Title: Topical application of antifibrinolytic drugs for on-pump cardiac surgery: a systematic review and meta-analysis.
Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20090301
Title: [Hemostatic management for cardiac surgical patients in the post-aprotinin era].
Journal: Masui. The Japanese journal of anesthesiology 20090301
Title: Effect of foreign surface pacification with albumin, aprotinin, propofol, and high-density lipoprotein.
Journal: The journal of extra-corporeal technology 20090301
Title: Aprotinin protects the cerebral microcirculation during cardiopulmonary bypass.
Journal: Perfusion 20090301
Title: Renal dysfunction in cardiac surgery: identifying potential risk factors.
Journal: Perfusion 20090301
Title: Engineering sugarcane cultivars with bovine pancreatic trypsin inhibitor (aprotinin) gene for protection against top borer (Scirpophaga excerptalis Walker).
Journal: Plant cell reports 20090201
Title: Inhibition of the 20S proteosome by a protein proteinase inhibitor: evidence that a natural serine proteinase inhibitor can inhibit a threonine proteinase.
Journal: Journal of biochemistry 20090201
Title: Bleeding in liver surgery: prevention and treatment.
Journal: Clinics in liver disease 20090201
Title: The impact of aprotinin on postoperative renal dysfunction in neonates undergoing cardiopulmonary bypass: a retrospective analysis.
Journal: Anesthesia and analgesia 20090201
Title: Use of methylene blue for catecholamine-refractory vasoplegia from protamine and aprotinin.
Journal: The Annals of thoracic surgery 20090201
Title: Antifibrinolytic therapy in complex spine surgery: a case-control study comparing aprotinin and tranexamic acid.
Journal: Orthopedics 20090201
Title: The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20090120
Title: Exploring the molecular design of protein interaction sites with molecular dynamics simulations and free energy calculations.
Journal: Biochemistry 20090120
Title: Aprotinin stimulates angiogenesis and human endothelial cell migration through the growth factor pleiotrophin and its receptor protein tyrosine phosphatase beta/zeta.
Journal: European journal of pharmacology 20090114
Title: The blood sparing effect and the safety of aprotinin compared to tranexamic acid in paediatric cardiac surgery.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090101
Title: Effect of anti-fibrinolytic therapy on experimental melanoma metastasis.
Journal: Clinical & experimental metastasis 20090101
Title: A SELDI-TOF MS procedure for the detection, quantitation, and preliminary characterization of low-molecular-weight recombinant proteins expressed in transgenic plants.
Journal: Proteomics 20090101
Title: CU-2010--a novel small molecule protease inhibitor with antifibrinolytic and anticoagulant properties.
Journal: Anesthesiology 20090101
Title: The aprotinin saga and the risks of conducting meta-analyses on small randomised controlled trials - a critique of a Cochrane review.
Journal: BMC health services research 20090101
Title: Purification and characterization of camel (Camelus dromedarius) milk amylase.
Journal: Preparative biochemistry & biotechnology 20090101
Title: Low dose aprotinin and low dose tranexamic acid in elective cardiac surgery with cardiopulmonary bypass.
Journal: Clinical hemorheology and microcirculation 20090101
Title: Bodo sp., a free-living flagellate, expresses divergent proteolytic activities from the closely related parasitic trypanosomatids.
Journal: The Journal of eukaryotic microbiology 20090101
Title: Aprotinin attenuates genomic expression variability following cardiac surgery.
Journal: Journal of cardiac surgery 20090101
Title: Assessment of aprotinin influence on periodontal clinical status and matrix metalloproteinases 1, 2 and their tissue inhibitors saliva concentrations in patients with chronic periodontitis.
Journal: Advances in medical sciences 20090101
Title: High-dose aprotinin does not affect troponin I, N-Terminal pro-B-type natriuretic peptid and renal function in children submitted to surgical correction with extracorporeal circulation.
Journal: Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular 20090101
Title: A comparison of the local effectiveness of mitomycin C, aprotinin, and Adcon-L in experimental peridural fibrosis.
Journal: Surgical neurology 20081201
Title: Stable-isotope labeling using an inducible viral infection system in suspension-cultured plant cells.
Journal: Journal of biomolecular NMR 20081201
Title: Aprotinin for patients exposed to clopidogrel before off-pump coronary bypass.
Journal: Asian cardiovascular & thoracic annals 20081201
Title: The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients.
Journal: Anesthesia and analgesia 20081201
Title: Management of patients undergoing multivalvular surgery for carcinoid heart disease: the role of the anaesthetist.
Journal: British journal of anaesthesia 20081101
Title: [Blood conservation approaches in orthopedic surgery].
Journal: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20081101
Title: Tranexamic acid and aprotinin in primary cardiac operations: an analysis of 220 cardiac surgical patients treated with tranexamic acid or aprotinin.
Journal: Anesthesia and analgesia 20081101
Title: The use of antifibrinolytic agents in spine surgery. A meta-analysis.
Journal: The Journal of bone and joint surgery. American volume 20081101
Title: Aprotinin and renal dysfunction.
Journal: Expert opinion on drug safety 20081101
Title: Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.
Journal: Journal of molecular biology 20081017
Title: Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron.
Journal: American journal of physiology. Renal physiology 20081001
Title: Tissue kallikrein elicits cardioprotection by direct kinin b2 receptor activation independent of kinin formation.
Journal: Hypertension (Dallas, Tex. : 1979) 20081001
Title: Protective effect of aprotinin on ischemia-reperfusion injury in rat ovary.
Journal: The journal of obstetrics and gynaecology research 20081001
Title: Aprotinin exacerbates left ventricular dysfunction after ischemia/reperfusion in mice lacking tumor necrosis factor receptor I.
Journal: Journal of cardiovascular pharmacology 20081001
Title: Severe intraoperative anaphylactic reaction: aprotinin and rocuronium.
Journal: Journal of cardiothoracic and vascular anesthesia 20081001
Title: Aprotinin and lysine analogues in high-risk cardiac surgery.
Journal: The New England journal of medicine 20080911
Title: Aprotinin and lysine analogues in high-risk cardiac surgery.
Journal: The New England journal of medicine 20080911
Title: Anti-inflammatory actions of aprotinin provide dose-dependent cardioprotection from reperfusion injury.
Journal: British journal of pharmacology 20080901
Title: A randomized, controlled trial of aprotinin in neonates undergoing open-heart surgery.
Journal: Paediatric anaesthesia 20080901
Title: Analgesic compound from sea anemone Heteractis crispa is the first polypeptide inhibitor of vanilloid receptor 1 (TRPV1).
Journal: The Journal of biological chemistry 20080829
Title: Spirodela (duckweed) as an alternative production system for pharmaceuticals: a case study, aprotinin.
Journal: Transgenic research 20080801
Title: Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy.
Journal: Pediatric nephrology (Berlin, Germany) 20080801
Title: The influence of aprotinin and tranexamic acid on platelet function and postoperative blood loss in cardiac surgery.
Journal: Anesthesia and analgesia 20080801
Title: Anaphylactic reaction after systemic application of aprotinin triggered by aprotinin-containing fibrin sealant.
Journal: Anesthesia and analgesia 20080801
Title: Impact of aprotinin on adverse clinical outcomes and mortality up to 12 years in a registry of 3,337 patients.
Journal: The Annals of thoracic surgery 20080801
Title: Aprotinin exerts differential and dose-dependent effects on myocardial contractility, oxidative stress, and cytokine release after ischemia-reperfusion.
Journal: The Annals of thoracic surgery 20080801
Title: Contemporary conduct of adult deep hypothermic circulatory arrest: possible roles of retrograde cerebral perfusion, anesthetic preconditioning, and aprotinin.
Journal: The Annals of thoracic surgery 20080801
Title: Safety of aprotinin (again).
Journal: Lancet (London, England) 20080705
Title: CABG-procedures in patients with pretreatment with the GPIIb/IIIa-receptor antagonist tirofiban (Aggrastat): modification of perioperative management?
Journal: International journal of cardiology 20080704
Title: Guideline on antiplatelet and anticoagulation management in cardiac surgery.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20080701
Title: Aprotinin is not associated with postoperative renal impairment after primary coronary surgery.
Journal: The Annals of thoracic surgery 20080701
Title: Molecular characterization of two novel isoforms and a soluble form of mouse CLEC-2.
Journal: Biochemical and biophysical research communications 20080627
Title: A chemical approach for detecting sulfenic acid-modified proteins in living cells.
Journal: Molecular bioSystems 20080601
Title: An affinity-based strategy for the design of selective displacers for the chromatographic separation of proteins.
Journal: Langmuir : the ACS journal of surfaces and colloids 20080601
Title: Prostate-specific kallikreins-2 and -4 enhance the proliferation of DU-145 prostate cancer cells through protease-activated receptors-1 and -2.
Journal: Molecular cancer research : MCR 20080601
Title: A comparison of aprotinin and lysine analogues in high-risk cardiac surgery.
Journal: The New England journal of medicine 20080529
Title: The aprotinin story--is BART the final chapter?
Journal: The New England journal of medicine 20080529
Title: Purification and characterization of aprotinin from porcine lungs.
Journal: Biotechnology letters 20080501
Title: Does perioperative use of aprotinin reduce the rejection rate in heart transplant recipients?
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20080501
Title: The impact of aprotinin on blood loss and blood transfusion in off-pump coronary artery bypass grafting.
Journal: The Annals of thoracic surgery 20080501
Title: The effect of aprotinin on risk of acute renal failure requiring dialysis after on-pump cardiac surgery.
Journal: Anaesthesia and intensive care 20080501
Title: Kunitz trypsin inhibitor: an antagonist of cell death triggered by phytopathogens and fumonisin b1 in Arabidopsis.
Journal: Molecular plant 20080501
Title: [Drugs to reduce transfusion needs during surgery].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080403
Title: In vitro simulation of thrombolysis inhibition.
Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20080401
Title: The intestine as source of cytotoxic mediators in shock: free fatty acids and degradation of lipid-binding proteins.
Journal: American journal of physiology. Heart and circulatory physiology 20080401
Title: An unusual fatal reaction to a test dose of aprotinin before elective thoracoabdominal aortic aneurysm repair.
Journal: European journal of anaesthesiology 20080401
Title: Antifibrinolytic therapy in surgery for congenital heart disease.
Journal: Anesthesia and analgesia 20080401
Title: Differential effects of epsilon-aminocaproic acid and aprotinin on matrix metalloproteinase release in patients following cardiopulmonary bypass.
Journal: Journal of cardiovascular pharmacology 20080401
Title: Current antifibrinolytic therapy for coronary artery revascularization.
Journal: AANA journal 20080401
Title: Pharmacologic methods to reduce perioperative bleeding.
Journal: Transfusion 20080301
Title: Perioperative management of aspirin resistance after off-pump coronary artery bypass grafting: possible role for aprotinin.
Journal: Transfusion 20080301
Title: Aprotinin confers neuroprotection by reducing excitotoxic cell death.
Journal: The Journal of thoracic and cardiovascular surgery 20080301
Title: High-dose aprotinin effectively reduces blood loss during on-pump coronary artery bypass grafting with bivalirudin anticoagulation.
Journal: The Journal of thoracic and cardiovascular surgery 20080301
Title: Endogenous pancreatic protease activity and methods for impeding their function.
Journal: Transplantation proceedings 20080301
Title: [Expression of a shrimp Kunitz-type protease inhibitor in Pichia pastoris and activity analysis].
Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080301
Title: Aprotinin during coronary-artery bypass grafting and risk of death.
Journal: The New England journal of medicine 20080221
Title: The effect of aprotinin on outcome after coronary-artery bypass grafting.
Journal: The New England journal of medicine 20080221
Title: Structural basis for accelerated cleavage of bovine pancreatic trypsin inhibitor (BPTI) by human mesotrypsin.
Journal: The Journal of biological chemistry 20080215
Title: Aprotinin--still courting controversy.
Journal: Lancet (London, England) 20080209
Title: Effect of aprotinin on renal dysfunction in patients undergoing on-pump and off-pump cardiac surgery: a retrospective observational study.
Journal: Lancet (London, England) 20080209
Title: Warm ischemia provokes inflammation and regional hypercoagulability within the heart during off-pump coronary artery bypass: a possible target for serine protease inhibition.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20080201
Title: Aprotinin and renal dysfunction after pediatric cardiac surgery.
Journal: Paediatric anaesthesia 20080201
Title: Effects of aprotinin dosage on renal function: an analysis of 8,548 cardiac surgical patients treated with different dosages of aprotinin.
Journal: Anesthesiology 20080201
Title: Characterization of azurocidin as a permeability factor in the retina: involvement in VEGF-induced and early diabetic blood-retinal barrier breakdown.
Journal: Investigative ophthalmology & visual science 20080201
Title: Perioperative renal outcome in cardiac surgical patients with preoperative renal dysfunction: aprotinin versus epsilon aminocaproic acid.
Journal: Journal of cardiothoracic and vascular anesthesia 20080201
Title: Case 1-2008. One institution's decreasing use of aprotinin during cardiac surgery in 2006.
Journal: Journal of cardiothoracic and vascular anesthesia 20080201
Title: Balancing conformational and oxidative kinetic traps during the folding of bovine pancreatic trypsin inhibitor (BPTI) with glutathione and glutathione disulfide.
Journal: Journal of the American Chemical Society 20080123
Title: Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta defensin 3.
Journal: Peptides 20080101
Title: Benefits and risks of aprotinin use during cardiac surgery.
Journal: Pharmacotherapy 20080101
Title: The protective effect of aprotinin and alpha-tocopherol on ischemia-reperfusion injury of the rat liver.
Journal: Transplantation proceedings 20080101
Title: Increased incidence of acute kidney injury with aprotinin use during cardiac surgery detected with urinary NGAL.
Journal: American journal of nephrology 20080101
Title: Aprotinin in cardiac surgery: a different point of view.
Journal: The heart surgery forum 20080101
Title: Influence of ultra-low dose Aprotinin on thoracic surgical operations: a prospective randomized trial.
Journal: Journal of cardiothoracic surgery 20080101
Title: Transthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor.
Journal: PloS one 20080101
Title: Efficacy of a high-dose aprotinin regimen for reducing transfusion requirements and inflammatory responses in adult cardiac surgery.
Journal: The Journal of international medical research 20080101
Title: Extending the scope of singlet-state spectroscopy.
Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20071221
Title: Aprotinin and perioperative complications in cardiac surgery.
Journal: The Journal of cardiovascular surgery 20071201
Title: [Antifibrinolytic agents and repeat open-heart surgery: a comparison of tranexamic acid and low dose aprotinin].
Journal: Annales de cardiologie et d'angeiologie 20071201
Title: Inhibition of thrombin generation in recalcified plasma.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20071201
Title: Aprotinin is safe in pediatric patients undergoing cardiac surgery.
Journal: The Journal of thoracic and cardiovascular surgery 20071201
Title: Pharmacologic strategies for combating the inflammatory response.
Journal: The journal of extra-corporeal technology 20071201
Title: Pharmacologic neuroprotection: the search continues.
Journal: The journal of extra-corporeal technology 20071201
Title: Antifibrinolytic therapy: evidence, bias, confounding (and politics!).
Journal: The journal of extra-corporeal technology 20071201
Title: Cardiac surgery with cardiopulmonary bypass: does aprotinin affect outcome?
Journal: British journal of anaesthesia 20071101
Title: [Aprotinin reduces bleeding during off-pump coronary artery bypass grafting in a patient on ticlopidine; report of a case].
Journal: Kyobu geka. The Japanese journal of thoracic surgery 20071101
Title: Purification of elastase-like chymotrypsin from cardamom shoot and Capsule borer [corrected].
Journal: Indian journal of experimental biology 20071101
Title: Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Journal: The Cochrane database of systematic reviews 20071017
Title: Finding protein-protein interaction patterns by contact map matching.
Journal: Genetics and molecular research : GMR 20071005
Title: Plasmin inhibition increases MMP-9 activity and decreases vein wall stiffness during venous thrombosis resolution.
Journal: The Journal of surgical research 20071001
Title: Profiling constitutive proteolytic events in vivo.
Journal: The Biochemical journal 20071001
Title: Evaluation of aprotinin and tranexamic acid in different in vitro and in vivo models of fibrinolysis, coagulation and thrombus formation.
Journal: Journal of thrombosis and haemostasis : JTH 20071001
Title: The impact of aprotinin on renal function after liver transplantation: an analysis of 1,043 patients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071001
Title: Aprotinin and anaphylaxis: analysis of 12,403 exposures to aprotinin in cardiac surgery.
Journal: The Annals of thoracic surgery 20071001
Title: [Local hemostasis during the carotid endarterectomy under condition of antithrombocytic therapy].
Journal: Klinichna khirurhiia 20071001
Title: Thermodynamic properties of BPTI variants with highly simplified amino acid sequences.
Journal: Journal of molecular biology 20070921
Title: Comparison of chromatographic ion-exchange resins VI. Weak anion-exchange resins.
Journal: Journal of chromatography. A 20070914
Title: Effects of aprotinin on gene expression and protein synthesis after ischemia and reperfusion in rats.
Journal: Circulation 20070911
Title: Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.
Journal: The Journal of biological chemistry 20070907
Title: Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function.
Journal: Journal of cellular physiology 20070901
Title: Anaphylactic shock in a beta-blocked child: usefulness of isoproterenol.
Journal: Paediatric anaesthesia 20070901
Title: Aprotinin does not prolong the Sonoclot aprotinin-insensitive activated clotting time.
Journal: Journal of clinical anesthesia 20070901
Title: Effect of recombinant aprotinin on postoperative blood loss and coronary vascular function in a canine model of cardiopulmonary bypass.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20070801
Title: Intraoperative coronary thrombosis with aprotinin in the prebypass period.
Journal: Journal of cardiothoracic and vascular anesthesia 20070801
Title: Case 4-2007. Aprotinin-induced cardiovascular collapse after a negative test dose in a patient scheduled for repeat mitral valve surgery.
Journal: Journal of cardiothoracic and vascular anesthesia 20070801
Title: The effect of aprotinin on brain ischemic-reperfusion injury after hemorrhagic shock in rats: an experimental study.
Journal: The Journal of trauma 20070801
Title: Comparison of structure, strength and cytocompatibility of a fibrin matrix supplemented either with tranexamic acid or aprotinin.
Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20070701
Title: Aprotinin use in cardiac surgery patients at low risk for requiring blood transfusion.
Journal: Pharmacotherapy 20070701
Title: Limitations with aprotinin in thoracic aortic surgery: understanding the clinical outcome beyond bleeding.
Journal: The Journal of thoracic and cardiovascular surgery 20070701
Title: Meta-analysis comparing the effectiveness and adverse outcomes of antifibrinolytic agents in cardiac surgery.
Journal: Circulation 20070605
Title: Potential effects of PKC or protease inhibitors on acute pancreatitis-induced tissue injury in rats.
Journal: Vascular pharmacology 20070601
Title: Plasmin decreases the BH3-only protein BimEL via the ERK1/2 signaling pathway in hepatocytes.
Journal: Biochimica et biophysica acta 20070601
Title: Design and evaluation of a chitosan-aprotinin conjugate for the peroral delivery of therapeutic peptides and proteins susceptible to enzymatic degradation.
Journal: Journal of drug targeting 20070601
Title: A tick protein with a modified Kunitz fold inhibits human tryptase.
Journal: Journal of molecular biology 20070511
Title: Selenoglutathione: efficient oxidative protein folding by a diselenide.
Journal: Biochemistry 20070508
Title: Factor V Leiden does not affect bleeding in aprotinin recipients after cardiopulmonary bypass.
Journal: Anesthesiology 20070401
Title: An anaphylactic reaction after primary exposure to an aprotinin test dose in a child with a severe milk allergy.
Journal: Journal of cardiothoracic and vascular anesthesia 20070401
Title: Pro: Aprotinin should be used in coronary artery bypass graft surgery with cardiopulmonary bypass.
Journal: Journal of cardiothoracic and vascular anesthesia 20070401
Title: Con: Aprotinin should not be used in cardiac surgery with cardiopulmonary bypass.
Journal: Journal of cardiothoracic and vascular anesthesia 20070401
Title: Impact of aspirin with or without clopidogrel on postoperative bleeding and blood transfusion in coronary surgical patients treated prophylactically with a low-dose of aprotinin.
Journal: European heart journal 20070401
Title: Topical use of antifibrinolytic agents reduces postoperative bleeding: a double-blind, prospective, randomized study.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20070301
Title: The effect of L-arginine and aprotinin on intestinal ischemia-reperfusion injury.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20070301
Title: Dual-color fluorescence-burst analysis to probe protein efflux through the mechanosensitive channel MscL.
Journal: Biophysical journal 20070215
Title: Mortality associated with aprotinin during 5 years following coronary artery bypass graft surgery.
Journal: JAMA 20070207
Title: Aprotinin--are there lessons learned?
Journal: JAMA 20070207
Title: [Local and systemic hemostasis in surgery].
Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20070201
Title: Protease activated receptors: clinical relevance to hemostasis and inflammation.
Journal: Hematology/oncology clinics of North America 20070201
Title: Effects of fibrinolytic inhibitors on chondrogenesis of bone-marrow derived mesenchymal stem cells in fibrin gels.
Journal: Biomechanics and modeling in mechanobiology 20070101
Title: Mutational analysis of protein solubility enhancement using short peptide tags.
Journal: Biopolymers 20070101
Title: Albumin is a redox-active crowding agent that promotes oxidative folding of cysteine-rich peptides.
Journal: Biopolymers 20070101
Title: Aprotinin; friend or foe? A review of recent medical literature.
Journal: European journal of anaesthesiology 20070101
Title: Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and meta-analysis.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101
Title: Immobilization of aprotinin to fibrinogen as a novel method for controlling degradation of fibrin gels.
Journal: Bioconjugate chemistry 20070101
Title: Effects of vitamin e, pentoxifylline and aprotinin on light-induced retinal injury.
Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20070101
Title: German cockroach frass proteases cleave pro-matrix metalloproteinase-9.
Journal: Experimental lung research 20070101
Title: In silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approach.
Journal: BMC structural biology 20070101
Title: Aprotinin and nafamostat mesilate in liver surgery: effect on blood loss.
Journal: Digestive surgery 20070101
Title: Identification of serine proteases from Leishmania braziliensis.
Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Title: Is there still a role for aprotinin in cardiac surgery?
Journal: Drug safety 20070101
Title: Effectiveness of treatment to prevent adhesions after abdominal surgery: an experimental evaluation in rats.
Journal: Advances in therapy 20070101
Title: Pro: Aprotinin has a good efficacy and safety profile relative to other alternatives for prevention of bleeding in cardiac surgery.
Journal: Anesthesia and analgesia 20061201
Title: Aprotinin and sevoflurane do not affect renal function during single-ventricle palliative surgery.
Journal: Anesthesia and analgesia 20061201
Title: Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A.
Journal: Endocrine-related cancer 20061201
Title: Aprotinin and renal risk in cardiac surgery.
Journal: Transfusion 20061201
Title: Aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery.
Journal: Transfusion 20061201
Title: Letter by van der Linden et al regarding article, 'Effect of clopidogrel premedication in off-pump cardiac surgery: are we forfeiting the benefits of reduced hemorrhagic sequelae?'.
Journal: Circulation 20061114
Title: Cost-effectiveness of cell salvage and alternative methods of minimising perioperative allogeneic blood transfusion: a systematic review and economic model.
Journal: Health technology assessment (Winchester, England) 20061101
Title: High-dose aprotinin in cardiac surgery: is high-dose high enough? An analysis of 8281 cardiac surgical patients treated with aprotinin.
Journal: Anesthesia and analgesia 20061101
Title: Full-dose aprotinin use in coronary artery bypass graft surgery: an analysis of perioperative pharmacotherapy and patient outcomes.
Journal: Anesthesia and analgesia 20061101
Title: Cardioprotective effect of aprotinin on myocardial ischemia/reperfusion injury during cardiopulmonary bypass.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20061101
Title: If you prick us, do we not bleed?
Journal: Anesthesiology 20061101
Title: Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?
Journal: Anesthesiology 20061101
Title: [Anesthesia in May-Hegglin anomaly].
Journal: Revista espanola de anestesiologia y reanimacion 20061101
Title: Aprotinin use in thoracic aortic surgery: safety and outcomes.
Journal: The Journal of thoracic and cardiovascular surgery 20061001
Title: Aprotinin improves cerebral protection: evidence from a survival porcine model.
Journal: The Journal of thoracic and cardiovascular surgery 20061001
Title: The critical role of aprotinin in controlling haemostasis in conjunction with non-pharmacological blood-saving strategies during routine coronary artery bypass surgery.
Journal: European journal of medical research 20060929
Title: [Aprotinin in cardiac surgery: more risks than usefulness?].
Journal: Der Anaesthesist 20060901
Title: Ventricular assist device support in children and adolescents as a bridge to heart transplantation.
Journal: The Annals of thoracic surgery 20060901
Title: The use of antifibrinolytic agents in total hip arthroplasty: a meta-analysis.
Journal: The Journal of arthroplasty 20060901
Title: The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold.
Journal: The Journal of biological chemistry 20060818
Title: Free energy calculations show that acidic P1 variants undergo large pKa shifts upon binding to trypsin.
Journal: Proteins 20060815
Title: Heparin modulates the 99-loop of factor IXa: effects on reactivity with isolated Kunitz-type inhibitor domains.
Journal: The Journal of biological chemistry 20060811
Title: Rapid evolution of the trophoblast kunitz domain proteins (TKDPs)-a multigene family in ruminant ungulates.
Journal: Journal of molecular evolution 20060801
Title: Aprotinin: effective, but risky?
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20060801
Title: Gene transfer to the gastrointestinal tract after peroral administration of recombinant adeno-associated virus type 2 vectors.
Journal: Journal of pediatric gastroenterology and nutrition 20060801
Title: Cardiovascular collapse due to massive pulmonary thromboembolism during orthotopic liver transplantation.
Journal: Journal of clinical anesthesia 20060801
Title: Attenuation of acute lung injury following lower limb ischemia/reperfusion: the pharmacological approach.
Journal: The Journal of cardiovascular surgery 20060801
Title: [The 'Seville' Consensus Document on Alternatives to Allogenic Blood Transfusion. Sociedades españolas de Anestesiología (SEDAR), Medicina Intensiva (SEMICYUC), Hematología y Hemoterapia (AEHH), Transfusión sanguínea (SETS) Trombosis y Hemostasia (SETH)].
Journal: Medicina clinica 20060718
Title: Role of the kallikrein-kinin system in Ang-(1-7)-induced vasodilation in mesenteric arterioles of Wistar rats studied in vivo-in situ.
Journal: Peptides 20060701
Title: Characterization of digestive proteolytic activity in Lygus hesperus Knight (Hemiptera: Miridae).
Journal: Journal of insect physiology 20060701
Title: Efficacy of FDA-approved hemostatic drugs to improve survival and reduce bleeding in rat models of uncontrolled hemorrhage.
Journal: Resuscitation 20060701
Title: Use of heparin upon reoperation in a pediatric patient with heparin-induced thrombocytopenia after disappearance of antibodies.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20060701
Title: The effect of aprotinin on activated protein C-mediated downregulation of endogenous thrombin generation.
Journal: British journal of haematology 20060701
Title: Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis.
Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060701
Title: Coagulopathy and inflammation in neonatal heart surgery: mechanisms and strategies.
Journal: The Annals of thoracic surgery 20060601
Title: Effects of half-dose aprotinin in off-pump coronary artery bypass grafting.
Journal: World journal of surgery 20060601
Title: Pharmacological approaches to reducing blood loss and transfusions in the surgical patient.
Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060601
Title: Aprotinin and the protease-activated receptor 1 thrombin receptor: antithrombosis, inflammation, and stroke reduction.
Journal: Seminars in cardiothoracic and vascular anesthesia 20060601
Title: Aprotinin in cardiac surgery.
Journal: The New England journal of medicine 20060504
Title: Aprotinin in cardiac surgery.
Journal: The New England journal of medicine 20060504
Title: Aprotinin in cardiac surgery.
Journal: The New England journal of medicine 20060504
Title: Aprotinin in cardiac surgery.
Journal: The New England journal of medicine 20060504
Title: NMR studies of BPTI aggregation by using paramagnetic relaxation reagents.
Journal: Biochimica et biophysica acta 20060501
Title: Fatal pulmonary microthrombi during surgical therapy for end-stage heart failure: possible association with antifibrinolytic therapy.
Journal: The Journal of thoracic and cardiovascular surgery 20060501
Title: Safety of bypass drug questioned.
Journal: Harvard heart letter : from Harvard Medical School 20060501
Title: [Effect of aprotinin on selected parameters of coagulation and drainage blood loss after cardiac operations in patients without coagulation disorders].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20060501
Title: An in-built proteinase inhibitor system for the protection of recombinant proteins recovered from transgenic plants.
Journal: Plant biotechnology journal 20060501
Title: Specific ion effects at protein surfaces: a molecular dynamics study of bovine pancreatic trypsin inhibitor and horseradish peroxidase in selected salt solutions.
Journal: The journal of physical chemistry. B 20060406
Title: Comparison of the effects of aprotinin and tranexamic acid on blood loss and red blood cell transfusion requirements during the late stages of liver transplantation.
Journal: Transfusion 20060401
Title: Tirofiban (Aggrastat) protects platelets and decreases platelet-granulocyte binding in an extracorporeal circulation model.
Journal: The Thoracic and cardiovascular surgeon 20060401
Title: Rapid quantitative characterization of protein interactions by composition gradient static light scattering.
Journal: Biophysical journal 20060315
Title: An unexpected inhibitory activity of Kunitz-type serine proteinase inhibitor derived from Boophilus microplus trypsin inhibitor on cathepsin L.
Journal: Biochemical and biophysical research communications 20060303
Title: Aprotinin and renal function at cardiac surgery.
Journal: European journal of anaesthesiology 20060301
Title: Aprotinin in cardiac surgery.
Journal: Expert review of cardiovascular therapy 20060301
Title: Aprotinin versus tranexamic acid: the controversy continues.
Journal: Transfusion 20060301
Title: A propensity score case-control comparison of aprotinin and tranexamic acid in high-transfusion-risk cardiac surgery.
Journal: Transfusion 20060301
Title: [Hemostatic drugs in a patient with antiphospholipid syndrome and clinically significant perioperative bleeding].
Journal: Revista espanola de anestesiologia y reanimacion 20060301
Title: Intranasal immunization of Balb/c mice against prion protein attenuates orally acquired transmissible spongiform encephalopathy.
Journal: Vaccine 20060227
Title: Aprotinin decreases reperfusion injury and allograft dysfunction in clinical lung transplantation.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060201
Title: Effect of aprotinin and recombinant variants on platelet protease-activated receptor 1 activation.
Journal: The Annals of thoracic surgery 20060201
Title: Invited commentary.
Journal: The Annals of thoracic surgery 20060201
Title: Evidence-based treatment of acute pancreatitis: a look at established paradigms.
Journal: Annals of surgery 20060201
Title: Midgut proteases of the cardamom shoot and capsule borer Conogethes punctiferalis (Lepidoptera: Pyralidae) and their interaction with aprotinin.
Journal: Bulletin of entomological research 20060201
Title: Effects of intraperitoneal vitamin E, melatonin and aprotinin on leptin expression in the guinea pig eye during experimental uveitis.
Journal: Acta ophthalmologica Scandinavica 20060201
Title: Aprotinin attenuates the elevation of pulmonary vascular resistance after cardiopulmonary bypass.
Journal: Journal of Korean medical science 20060201
Title: The risk associated with aprotinin in cardiac surgery.
Journal: The New England journal of medicine 20060126
Title: Aprotinin shows both hemostatic and antithrombotic effects during off-pump coronary artery bypass grafting.
Journal: The Annals of thoracic surgery 20060101
Title: [Anaesthesiological management in orthotopic liver transplantation -- results of a survey].
Journal: Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 20060101
Title: Predicting and preventing adverse neurologic outcomes with cardiac surgery.
Journal: Journal of cardiac surgery 20060101
Title: Protease activities of Acanthamoeba polyphaga and Acanthamoeba castellanii.
Journal: Canadian journal of microbiology 20060101
Title: Elastic modulus-based thrombelastographic quantification of plasma clot fibrinolysis with progressive plasminogen activation.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20060101
Title: Mechanical properties of electrospun fibrinogen structures.
Journal: Acta biomaterialia 20060101
Title: Antifibrinolytics in liver transplantation.
Journal: International anesthesiology clinics 20060101
Title: Aprotinin to improve cerebral outcome after hypothermic circulatory arrest: a study in a surviving porcine model.
Journal: The heart surgery forum 20060101
Title: Effects of minimal dose aprotinin on blood loss and fibrinolytic system-complement activation in coronary artery bypass grafting surgery.
Journal: Journal of cardiac surgery 20060101
Title: Characterization of two whey protein genes in the Australian dasyurid marsupial, the stripe-faced dunnart (Sminthopsis macroura).
Journal: Cytogenetic and genome research 20060101
Title: The GH-IGF-IGFBP axis is changed in Turner syndrome: partial normalization by HRT.
Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20060101
Title: Glutathione restores collagen degradation in TGF-beta-treated fibroblasts by blocking plasminogen activator inhibitor-1 expression and activating plasminogen.
Journal: American journal of physiology. Lung cellular and molecular physiology 20051201
Title: The use of therapeutic medications for soft-tissue injuries in sports medicine.
Journal: The Medical journal of Australia 20051003
Title: Nonuniform charge scaling (NUCS): a practical approximation of solvent electrostatic screening in proteins.
Journal: Journal of computational chemistry 20051001
Title: Distribution and residual activity of two insecticidal proteins, avidin and aprotinin, expressed in transgenic tobacco plants, in the bodies and frass of Spodoptera litura larvae following feeding.
Journal: Journal of insect physiology 20051001
Title: Aprotinin attenuated ischemia-reperfusion injury in an isolated rat lung model after 18-hours preservation.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20051001
Title: Fibrinolytic inhibitors in off-pump coronary surgery: a prospective, randomized, double-blind TAP study (tranexamic acid, aprotinin, placebo).
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20051001
Title: The effects of aprotinin and tranexamic acid on thrombin generation and fibrinolytic response after cardiac surgery.
Journal: Acta anaesthesiologica Scandinavica 20051001
Title: Variability of biological effects of silicas: different degrees of activation of the fifth component of complement by amorphous silicas.
Journal: Toxicology and applied pharmacology 20051001
Title: Does the combination of aprotinin and angiotensin-converting enzyme inhibitor cause renal failure after cardiac surgery?
Journal: The Annals of thoracic surgery 20051001
Title: Anaphylaxis to aprotinin in fibrin sealant.
Journal: Internal medicine (Tokyo, Japan) 20051001
Title: Overview of clinical efficacy and safety of pharmacologic strategies for blood conservation.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050915
Title: Improving clinical outcomes in coronary artery bypass graft surgery.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050915
Title: Systemic inflammatory response to coronary artery bypass graft surgery.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050915
Title: Review and application of serine protease inhibition in coronary artery bypass graft surgery.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050915
Title: Aprotinin reduces bleeding and blood product use in patients treated with clopidogrel before coronary artery bypass grafting.
Journal: The Annals of thoracic surgery 20050901
Title: Hemodilution and surgical hemostasis contribute significantly to transfusion requirements in patients undergoing coronary artery bypass.
Journal: The Journal of thoracic and cardiovascular surgery 20050901
Title: Aprotinin improves kidney function and decreases tubular cell apoptosis and proapoptotic signaling after renal ischemia-reperfusion.
Journal: The Journal of thoracic and cardiovascular surgery 20050901
Title: Kidney-specific proteins in patients receiving aprotinin at high- and low-dose regimens during coronary artery bypass graft with cardiopulmonary bypass.
Journal: European journal of anaesthesiology 20050901
Title: The kallikrein-kinin system: current and future pharmacological targets.
Journal: Journal of pharmacological sciences 20050901
Title: The effect of temperature and aprotinin during cardiopulmonary bypass on three different methods of activated clotting time measurement.
Journal: The journal of extra-corporeal technology 20050901
Title: Aprotinin preserves cellular junctions and reduces myocardial edema after regional ischemia and cardioplegic arrest.
Journal: Circulation 20050830
Title: Aprotinin decreases postoperative bleeding and number of transfusions in patients on clopidogrel undergoing coronary artery bypass graft surgery: a double-blind, placebo-controlled, randomized clinical trial.
Journal: Circulation 20050830
Title: Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: calculation of structural and dynamic properties.
Journal: Proteins 20050815
Title: Determination of the cytotoxic effect of Clostridium histolyticum culture supernatant on HeLa cells in the presence of protease inhibitors.
Journal: FEMS immunology and medical microbiology 20050801
Title: Protective effect of aprotinin against lung damage in patients undergoing CABG surgery.
Journal: Acta cardiologica 20050801
Title: Coupling of size-exclusion chromatography to a continuous assay for subtilisin using a fluorescence resonance energy transfer peptide substrate: testing of two standard inhibitors.
Journal: Journal of chromatography. A 20050722
Title: A lecithin-based microemulsion of rh-insulin with aprotinin for oral administration: Investigation of hypoglycemic effects in non-diabetic and STZ-induced diabetic rats.
Journal: International journal of pharmaceutics 20050714
Title: Plasmin induces smooth muscle cell proliferation.
Journal: The Journal of surgical research 20050701
Title: Pitfalls of immunoassay and sample for IGF-I: comparison of different assay methodologies using various fresh and stored serum samples.
Journal: Clinical biochemistry 20050701
Title: Comparison of two strategies for the management of antiplatelet therapy during urgent surgery.
Journal: The Annals of thoracic surgery 20050701
Title: Aprotinin and epsilon aminocaproic acid are effective in reducing blood loss after primary total hip arthroplasty--a prospective randomized double-blind placebo-controlled study.
Journal: Journal of thrombosis and haemostasis : JTH 20050701
Title: Aprotinin: role in minimizing perioperative blood loss.
Journal: Plastic and reconstructive surgery 20050701
Title: Structure-function relationships in serine protease-bovine pancreatic trypsin inhibitor interaction.
Journal: Protein and peptide letters 20050701
Title: Exosite-mediated substrate recognition of factor IX by factor XIa. The factor XIa heavy chain is required for initial recognition of factor IX.
Journal: The Journal of biological chemistry 20050624
Title: Role of the mucous/glycocalyx layers in insulin permeation across the rat ileal membrane.
Journal: International journal of pharmaceutics 20050613
Title: In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases.
Journal: American journal of physiology. Lung cellular and molecular physiology 20050601
Title: Identification of a novel pulmonary oedema producing toxin from Indian red scorpion (Mesobuthus tamulus) venom.
Journal: Toxicon : official journal of the International Society on Toxinology 20050501
Title: Evidence-based review of the role of aprotinin in blood conservation during orthopaedic surgery.
Journal: The Journal of bone and joint surgery. American volume 20050501
Title: The study of protein folding and dynamics by determination of intramolecular distance distributions and their fluctuations using ensemble and single-molecule FRET measurements.
Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20050501
Title: In vivo biological performance of composites combining micro-macroporous biphasic calcium phosphate granules and fibrin sealant.
Journal: Archives of orthopaedic and trauma surgery 20050401
Title: Hypothermia-induced platelet aggregation: no effect of aprotinin (trasylol) but inhibition by eptifibatide (integrilin).
Journal: The Thoracic and cardiovascular surgeon 20050401
Title: Medical haemostasis in acute hepatocyte injury and experimental liver trauma.
Journal: ANZ journal of surgery 20050401
Title: Aprotinin and hemostasis.
Journal: Journal of neurosurgery 20050401
Title: Effect of aprotinin on in vitro cerebral endothelial ICAM-1 expression induced by astrocyte-conditioned medium.
Journal: European journal of anaesthesiology 20050401
Title: Purification and characterization of a hemorrhagic metalloproteinase from Bothrops lanceolatus (Fer-de-lance) snake venom.
Journal: Toxicon : official journal of the International Society on Toxinology 20050315
Title: The interaction of human tryptase-beta with small molecule inhibitors provides new insights into the unusual functional instability and quaternary structure of the protease.
Journal: Biochemistry 20050308
Title: Evaluation of a fibrin-based skin substitute prepared in a defined keratinocyte medium.
Journal: International journal of pharmaceutics 20050303
Title: Reducing allogeneic transfusion in cardiac surgery: a randomized double-blind placebo-controlled trial of antifibrinolytic therapies used in addition to intra-operative cell salvage.
Journal: British journal of anaesthesia 20050301
Title: 1.70 A X-ray structure of human apo kallikrein 1: structural changes upon peptide inhibitor/substrate binding.
Journal: Proteins 20050301
Title: [Effects of topical applications of aprotinin and tranexamic acid on blood loss after open heart surgery].
Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20050301
Title: Preparation of protected peptidyl thioester intermediates for native chemical ligation by Nalpha-9-fluorenylmethoxycarbonyl (Fmoc) chemistry: considerations of side-chain and backbone anchoring strategies, and compatible protection for N-terminal cysteine.
Journal: The journal of peptide research : official journal of the American Peptide Society 20050301
Title: Forty years of clinical aprotinin use: a review of 124 hypersensitivity reactions.
Journal: The Annals of thoracic surgery 20050201
Title: Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid, aprotinin or a combination?
Journal: Paediatric anaesthesia 20050101
Title: Graph-representation of oxidative folding pathways.
Journal: BMC bioinformatics 20050101
Title: Antifibrinolytics in orthotopic liver transplantation: current status and controversies.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050101
Title: Stability of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 measured by the IMMULITE automated chemiluminescence assay system in different blood specimens.
Journal: Clinical laboratory 20050101
Title: [Cryoplasma-antienzymatic therapy for aspiration pneumonia in neonatal infants with esophageal atresia].
Journal: Anesteziologiia i reanimatologiia 20050101
Title: Are antifibrinolytic drugs equivalent in reducing blood loss and transfusion in cardiac surgery? A meta-analysis of randomized head-to-head trials.
Journal: BMC cardiovascular disorders 20050101
Title: [General anesthesia components during abdominal surgeries in patients with abdominal sepsis].
Journal: Khirurgiia 20050101
Title: [Effects of aminocapronic acid and small-dose trasilol on blood loss after cardiac surgery with extracorporeal circulation].
Journal: Anesteziologiia i reanimatologiia 20050101
Title: Randomized controlled trials of aprotinin in cardiac surgery: could clinical equipoise have stopped the bleeding?
Journal: Clinical trials (London, England) 20050101
Title: Aprotinin decreases ischemic damage during coronary revascularization.
Journal: Journal of cardiac surgery 20050101
Title: [Comparative assessment of methods for prevention of microvascular anastomotic thrombosis at reparative plastic surgery for cancer].
Journal: Anesteziologiia i reanimatologiia 20050101
Title: Purification and characterization of an alkaline serine protease producing angiotensin I-converting enzyme inhibitory peptide from Bacillus sp. SS103.
Journal: Journal of medicinal food 20050101
Title: Comparison of textilinin-1 with aprotinin as serine protease inhibitors and as antifibrinolytic agents.
Journal: Pathophysiology of haemostasis and thrombosis 20050101
Title: Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants.
Journal: Journal of molecular biology 20041203
Title: Endopeptidase activity of larval Lacanobia oleracea corpus allatum: metabolism of Manduca sexta allatostatin and allatotropin.
Journal: Archives of insect biochemistry and physiology 20041201
Title: Prevention of adhesions by sodium chromoglycate, dexamethasone, saline and aprotinin after pelvic surgery.
Journal: ANZ journal of surgery 20041201
Title: Hemostatic agents.
Journal: Transfusion 20041201
Title: Aprotinin and hemostasis monitoring concerns during cardiac surgery.
Journal: The journal of extra-corporeal technology 20041201
Title: Aprotinin dosing: how much is enough?
Journal: The journal of extra-corporeal technology 20041201
Title: Prostasin, a membrane-anchored serine peptidase, regulates sodium currents in JME/CF15 cells, a cystic fibrosis airway epithelial cell line.
Journal: American journal of physiology. Lung cellular and molecular physiology 20041101
Title: Clopidogrel and postoperative bleeding.
Journal: The Annals of thoracic surgery 20041101
Title: [Treatment of acute pancreatitis with protease inhibitor, H2 receptor antagonist and somatostatin analogue].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20041101
Title: Treatment of acute pancreatitis with protease inhibitors: a meta-analysis.
Journal: European journal of gastroenterology & hepatology 20041101
Title: (Pre-)osteoclasts induce retraction of osteoblasts before their fusion to osteoclasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20041001
Title: Reduction of myocardial reperfusion injury by aprotinin after regional ischemia and cardioplegic arrest.
Journal: The Journal of thoracic and cardiovascular surgery 20041001
Title: Substrate-dependent modulation of the mechanism of factor XIa inhibition.
Journal: Biochemistry 20040921
Title: Aprotinin inhibits local platelet trapping and improves tissue destruction in hepatic cryosurgery.
Journal: Surgery 20040901
Title: Effect of aprotinin on clinical outcomes in coronary artery bypass graft surgery: a systematic review and meta-analysis of randomized clinical trials.
Journal: The Journal of thoracic and cardiovascular surgery 20040901
Title: Topographical properties of polymer films deposited in capillaries for electrophoretic separations of large organic molecules.
Journal: Journal of separation science 20040901
Title: First-principles calculations of protein circular dichroism in the near ultraviolet.
Journal: Biochemistry 20040831
Title: Bitis gabonica (Gaboon viper) snake venom gland: toward a catalog for the full-length transcripts (cDNA) and proteins.
Journal: Gene 20040804
Title: Off-pump epicardial tissue sealing--a novel method for atrioventricular disruption complicating mitral valve procedures.
Journal: The Annals of thoracic surgery 20040801
Title: Blood conservation in liver transplantation: The role of aprotinin.
Journal: Journal of cardiothoracic and vascular anesthesia 20040801
Title: Application of the poly-N-acetyl glucosamine-derived rapid deployment hemostat trauma dressing in severe/lethal Swine hemorrhage trauma models.
Journal: The Journal of trauma 20040701
Title: Comparison of poly-N-acetyl glucosamine with commercially available topical hemostats for achieving hemostasis in coagulopathic models of splenic hemorrhage.
Journal: The Journal of trauma 20040701
Title: Role of an aprotinin-sensitive protease in protein kinase Calpha-mediated activation of cytosolic phospholipase A2 by calcium ionophore (A23187) in pulmonary endothelium.
Journal: Cellular signalling 20040601
Title: Xanthine oxidase activates pro-matrix metalloproteinase-2 in cultured rat vascular smooth muscle cells through non-free radical mechanisms.
Journal: Archives of biochemistry and biophysics 20040601
Title: Aprotinin: a pharmacologic overview.
Journal: Orthopedics 20040601
Title: Efficacy and safety of aprotinin in cardiac surgery.
Journal: Orthopedics 20040601
Title: Intraoperative blood management in joint replacement surgery.
Journal: Orthopedics 20040601
Title: Prevention of cardiac fibrosis and left ventricular dysfunction in diabetic cardiomyopathy in rats by transgenic expression of the human tissue kallikrein gene.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501
Title: Degradation of mutated bovine pancreatic trypsin inhibitor in the yeast vacuole suggests post-endoplasmic reticulum protein quality control.
Journal: The Journal of biological chemistry 20040409
Title: Human airway trypsin-like protease increases mucin gene expression in airway epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20040401
Title: Tissue kallikrein increases duration of survival after prolonged coronary artery ligation in hypertensive rats.
Journal: Pharmacology 20040401
Title: Exosite occupation by heparin enhances the reactivity of blood coagulation factor IXa.
Journal: Biochemistry 20040316
Title: Plasma MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 during human orthotopic liver transplantation. The effect of aprotinin and the relation to ischemia/reperfusion injury.
Journal: Thrombosis and haemostasis 20040301
Title: Sealing of the mediastinum with a local hemostyptic agent reduces chest tube duration after complete mediastinal lymph node dissection for stage I and II non-small cell lung carcinoma.
Journal: The Annals of thoracic surgery 20040301
Title: The cerebroprotective effects of pentoxifylline and aprotinin during cardiopulmonary bypass in dogs.
Journal: Perfusion 20040301
Title: [Pharmacological alternatives to blood transfusion: what is new about?].
Journal: Medicina clinica 20040221
Title: Neutrophils both reduce and increase permeability in a cell culture model of the blood-brain barrier.
Journal: Brain research 20040220
Title: Native-like conformations are sampled by partially folded and disordered variants of bovine pancreatic trypsin inhibitor.
Journal: Biochemistry 20040217
Title: The effect of tranexamic acid in fibrin sealant on adhesion formation in the rat.
Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20040215
Title: Effects of epsilon-aminocaproic acid and aprotinin on leukocyte-platelet adhesion in patients undergoing cardiac surgery.
Journal: Anesthesiology 20040201
Title: Effects of nafamostat mesilate and minimal-dose aprotinin on blood-foreign surface interactions in cardiopulmonary bypass.
Journal: The Annals of thoracic surgery 20040201
Title: The potential role of aprotinin in the perioperative management of malignant tumors.
Journal: Journal of the American College of Surgeons 20040201
Title: The prophylactic use of tranexamic acid and aprotinin in orthotopic liver transplantation: a comparative study.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040201
Title: Vasopressin for treatment of shock following aprotinin administration.
Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20040201
Title: The importance of aprotinin and pentoxifylline in preventing leukocyte sequestration and lung injury caused by protamine at the end of cardiopulmonary bypass surgery.
Journal: The Thoracic and cardiovascular surgeon 20040201
Title: Impact of tranexamic acid vs. aprotinin on blood loss and transfusion requirements after cardiopulmonary bypass: a prospective, randomised, double-blind trial.
Journal: Current medical research and opinion 20040101
Title: Strategies for minimizing blood loss in orthopedic surgery.
Journal: Seminars in hematology 20040101
Title: [How I treat...acute pancreatitis: a literature review].
Journal: Revue medicale de Liege 20040101
Title: Possible absorption of antidiuretic hormone in isolated rat intestine.
Journal: Bulletin of experimental biology and medicine 20040101
Title: Reduction of active elastase concentration by means of immobilized inhibitors: a novel therapeutic approach.
Journal: Biotechnology progress 20040101
Title: Aprotinin suppresses ACE-inhibitor cough triggered by TAME-esterase.
Journal: Medical hypotheses 20040101
Title: Protective effects of intraperitoneal vitamin C, aprotinin and melatonin administration on retinal edema during experimental uveitis in the guinea pig.
Journal: Cell biochemistry and function 20040101
Title: Expression, purification, biochemical and pharmacological characterization of a recombinant aprotinin variant.
Journal: Arzneimittel-Forschung 20040101
Title: [Aprotinin in the correction of the hemodynamic syndrome of systemic inflammatory response in surgeries with extracorporeal circulation].
Journal: Anesteziologiia i reanimatologiia 20040101
Title: Aprotinin ameliorates ischemia/reperfusion injury in a rat hind limb model.
Journal: Vascular pharmacology 20040101
Title: [Aprotinin reduces myocardial injury in the off-pump coronary artery bypass grafting].
Journal: Zhonghua yi xue za zhi 20031210
Title: Protease inhibitors in the treatment of hereditary angioedema.
Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20031201
Title: Plasminogen activator activity and inhibition in rabbit tears after photorefractive keratectomy.
Journal: Experimental eye research 20031201
Title: The effects of aprotinin on platelet function in blood exposed to eptifibatide: an in vitro analysis.
Journal: The journal of extra-corporeal technology 20031201
Title: Biochemistry of serine protease inhibitors and their mechanisms of action: a review.
Journal: The journal of extra-corporeal technology 20031201
Title: Use of aprotinin in patients undergoing deep hypothermic circulatory arrest: a review.
Journal: The journal of extra-corporeal technology 20031201
Title: The use of aprotinin in pediatric patients: a review.
Journal: The journal of extra-corporeal technology 20031201
Title: Anaesthetic management of coronary artery bypass grafting in a patient with central core disease and susceptibility to malignant hyperthermia on statin therapy.
Journal: British journal of anaesthesia 20031101
Title: Antifibrinolytic therapy during cardiopulmonary bypass reduces proinflammatory cytokine levels: a randomized, double-blind, placebo-controlled study of epsilon-aminocaproic acid and aprotinin.
Journal: The Journal of thoracic and cardiovascular surgery 20031101
Title: Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin.
Journal: Journal of molecular biology 20031031
Title: Identification of a residue critical for maintaining the functional conformation of BPTI.
Journal: Journal of molecular biology 20031017
Title: Urokinase type plasminogen activator receptor is involved in insulin-like growth factor-induced migration of rhabdomyosarcoma cells in vitro.
Journal: Journal of cellular physiology 20031001
Title: A randomized trial of aprotinin (Trasylol) on blood loss, blood product requirement, and myocardial injury in total arterial grafting.
Journal: The Journal of thoracic and cardiovascular surgery 20031001
Title: Protein kinase C inhibition induces DNA fragmentation in COLO 205 cells which is blocked by cysteine protease inhibition but not mediated through caspase-3.
Journal: Experimental cell research 20030910
Title: The management of perioperative bleeding.
Journal: Blood reviews 20030901
Title: The solution structure of bovine pancreatic trypsin inhibitor at high pressure.
Journal: Protein science : a publication of the Protein Society 20030901
Title: The effects of serine proteinase inhibitors on bone resorption in vitro.
Journal: The Journal of endocrinology 20030901
Title: Intracellular cleavage of human influenza a virus hemagglutinin and its inhibition.
Journal: Biochemistry. Biokhimiia 20030901
Title: An evaluation of endogenous pancreatic enzyme levels after human islet isolation.
Journal: Pancreas 20030801
Title: Efficacy of aprotinin in children undergoing craniofacial surgery.
Journal: Journal of neurosurgery 20030801
Title: Adaptive evolution in the snake venom Kunitz/BPTI protein family.
Journal: FEBS letters 20030717
Title: Endostatin induces autophagic cell death in EAhy926 human endothelial cells.
Journal: Histology and histopathology 20030701
Title: [Lepirudin during cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia].
Journal: Annales francaises d'anesthesie et de reanimation 20030701
Title: Dose-dependent effect of aprotinin on aggravated pro-inflammatory cytokines in patients with pulmonary hypertension following cardiopulmonary bypass.
Journal: Cardiovascular drugs and therapy 20030701
Title: Major kinetic traps for the oxidative folding of leech carboxypeptidase inhibitor.
Journal: Biochemistry 20030610
Title: The bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor): a milestone protein.
Journal: Current protein & peptide science 20030601
Title: High pressure induces the formation of aggregation-prone states of proteins under reducing conditions.
Journal: Biophysical chemistry 20030501
Title: Effect of membranotropic and mucoadhesive formulations of protein proteinase inhibitors on bovine herpes virus-1 reproduction.
Journal: International journal of pharmaceutics 20030430
Title: [Tranexamic acid versus aprotinin for the prevention of bleeding during mitral valve surgery ].
Journal: Annales de cardiologie et d'angeiologie 20030401
Title: Application of a gratuitous induction system in Kluyveromyces lactis for the expression of intracellular and secreted proteins during fed-batch culture.
Journal: Biotechnology and bioengineering 20030320
Title: Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.
Journal: Blood 20030301
Title: Evaluation of tissue kallikrein activity on survival time after acute coronary artery ligation in hypertensive rats.
Journal: International immunopharmacology 20030301
Title: Effect of a protease inhibitor on in vitro stability of intact parathyroid hormone.
Journal: Annals of clinical biochemistry 20030301
Title: Reduction of blood loss using high-dose aprotinin in major orthopaedic surgery: a prospective, double-blind, randomised and placebo-controlled study.
Journal: The Journal of bone and joint surgery. British volume 20030301
Title: Use of aprotinin during cardiopulmonary bypass in a patient with protein C deficiency.
Journal: The journal of extra-corporeal technology 20030301
Title: A review of anti-inflammatory strategies in cardiac surgery.
Journal: Perfusion 20030301
Title: Aprotinin restores the adhesive capacity of dysfunctional platelets.
Journal: Thrombosis research 20030215
Title: Formation of active monomers from tetrameric human beta-tryptase.
Journal: The Biochemical journal 20030201
Title: Antifibrinolytic therapy and perioperative blood loss in cancer patients undergoing major orthopedic surgery.
Journal: Anesthesiology 20030201
Title: Different mechanisms contribute to the biphasic pattern of carboxypeptidase U (TAFIa) generation during in vitro clot lysis in human plasma.
Journal: Thrombosis and haemostasis 20030201
Title: Stroke after cardiac surgery: a retrospective analysis of the effect of aprotinin dosing regimens.
Journal: The Annals of thoracic surgery 20030201
Title: Aprotinin and preservation of myocardial function after ischemia-reperfusion injury.
Journal: The Annals of thoracic surgery 20030201
Title: Cleavage of human fibronectin and other basement membrane-associated proteins by a Cryptococcus neoformans serine proteinase.
Journal: Microbial pathogenesis 20030201
Title: Bacterial lipopolysaccharide-stimulated release of tumor necrosis factor-alpha from the isolated rat heart: the effect of aprotinin and forskolin.
Journal: The American surgeon 20030201
Title: Aprotinin reduces vasoactive medication use during adult liver transplantation.
Journal: Journal of clinical anesthesia 20030201
Title: Inhibition of membrane-type serine protease 1/matriptase by natural and synthetic protease inhibitors.
Journal: Journal of nutritional science and vitaminology 20030201
Title: Fibrinolysis inhibitors adversely affect remodeling of tissues sealed with fibrin glue.
Journal: Biomaterials 20030101
Title: The effect of aprotinin on ischemia-reperfusion injury in an in situ normothermic ischemic lung model.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20030101
Title: Aprotinin inhibits leukocyte-endothelial cell interactions after hemorrhage and reperfusion.
Journal: The Annals of thoracic surgery 20030101
Title: Does aprotinin influence the inflammatory response to cardiopulmonary bypass in patients?
Journal: The Journal of thoracic and cardiovascular surgery 20030101
Title: Aprotinin: a serine protease inhibitor with therapeutic actions: its interaction with ACE inhibitors.
Journal: Current pharmaceutical design 20030101
Title: Addition of side chains to a known backbone with defined side-chain centroids.
Journal: Biophysical chemistry 20030101
Title: Combined protective effect of a fungal Cu/Zn-containing superoxide dismutase and rimantadine hydrochloride in experimental murine influenza a virus infection.
Journal: Acta virologica 20030101
Title: [Therapy strategy in the treatment of patients with drug-resistant pulmonary tuberculosis].
Journal: Problemy tuberkuleza i boleznei legkikh 20030101
Title: [Intracellular disorders in myocardium of dogs during cardiogenic shock and possibilities of their correction].
Journal: Anesteziologiia i reanimatologiia 20030101
Title: Aprotinin reduces ischemia-reperfusion injury in the retina of guinea pigs.
Journal: European journal of ophthalmology 20030101
Title: Free energy calculations and ligand binding.
Journal: Advances in protein chemistry 20030101
Title: Validation of a chemiluminescent enzyme immunometric assay for plasma adrenocorticotropic hormone in the dog.
Journal: Veterinary clinical pathology 20030101
Title: Antifibrinolytics.
Journal: Acta anaesthesiologica Belgica 20030101
Title: [To what extent does Trasylol decrease the need for blood and blood derivatives in postoperative acetylsalicylic acid (ASA)-induced hemorrhage in CABG surgery?].
Journal: Medicinski arhiv 20030101
Title: [Our experience on the effect of complex treatment with gordox in patients with acute and chronic-recurrent pancreatitis].
Journal: Khirurgiia 20030101
Title: Insight into the factors influencing the backbone dynamics of three homologous proteins, dendrotoxins I and K, and BPTI: FTIR and time-resolved fluorescence investigations.
Journal: Biochemistry 20021224
Title: In vitro inhibition of bovine herpes virus 1 reproduction with native and microencapsulated proteinase inhibitor aprotinin.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20021213
Title: Gibberellin-mediated proteasome-dependent degradation of the barley DELLA protein SLN1 repressor.
Journal: The Plant cell 20021201
Title: Labeling proteins via hole burning of their aromatic amino acids: pressure tuning spectroscopy of BPTI.
Journal: Biophysical journal 20021201
Title: The effect of surface modification and aprotinin on cellular injury during simulated cardiopulmonary bypass.
Journal: The journal of extra-corporeal technology 20021201
Title: Soluble adhesion molecules in coronary surgery and cardiopulmonary bypass with pump prime aprotinin.
Journal: Scandinavian cardiovascular journal : SCJ 20021201
Title: Selected contribution: limiting Na(+) transport rate in airway epithelia from alpha-ENaC transgenic mice: a model for pulmonary edema.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20021101
Title: Cardioprotective effects of the serine protease inhibitor aprotinin after regional ischemia and reperfusion on the beating heart.
Journal: The Journal of thoracic and cardiovascular surgery 20021101
Title: The urokinase plasminogen activator: an interesting way to improve myoblast migration following their transplantation.
Journal: Experimental cell research 20021101
Title: Aprotinin counteracts heparin-induced inhibition of platelet contractile force.
Journal: Thrombosis research 20021101
Title: Evolution of hematophagy in ticks: common origins for blood coagulation and platelet aggregation inhibitors from soft ticks of the genus Ornithodoros.
Journal: Molecular biology and evolution 20021001
Title: Aprotinin reduces blood loss in off-pump coronary artery bypass (OPCAB) surgery.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20021001
Title: Risk of anaphylaxis from aprotinin re-exposure during LVAD removal and heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20021001
Title: A model of the direct and indirect effects of aprotinin administration on the overall costs of coronary revascularization surgery in a university teaching hospital cardiothoracic unit.
Journal: Clinical therapeutics 20021001
Title: Improved survival of patients undergoing palliation of hypoplastic left heart syndrome: lessons learned from 115 consecutive patients.
Journal: Circulation 20020924
Title: Aprotinin impairs coronary endothelial function and down-regulates endothelial NOS in rat coronary microvascular endothelial cells.
Journal: Cardiovascular research 20020901
Title: Hemodynamic performance of an unstented xenograft mitral valve substitute.
Journal: The Journal of thoracic and cardiovascular surgery 20020901
Title: NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability.
Journal: Journal of molecular biology 20020823
Title: Urokinase induces its own expression in Beas2B lung epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20020801
Title: Aprotinin mediated antioxidant effect in Cardiosurgery with mechanical cardiorespiratory support (CMCS).
Journal: The Journal of cardiovascular surgery 20020801
Title: Differential effects of aprotinin and tranexamic acid on endotoxin desensitization of blood cells induced by circulation through an isolated extracorporeal circuit.
Journal: Journal of cardiothoracic and vascular anesthesia 20020801
Title: Characterisation of Ag1, the major species-specific contaminant of bovine crude heparin, and its identification as an aprotinin/heparin complex.
Journal: Journal of pharmaceutical and biomedical analysis 20020701
Title: Functional dissociation between proforms and mature forms of proteinase 3, azurocidin, and granzyme B in regulation of granulopoiesis.
Journal: Experimental hematology 20020701
Title: [Determination of purity of different types of aprotinin by micellar electrokinetic capillary chromatography].
Journal: Se pu = Chinese journal of chromatography 20020701
Title: Effect of exogenous and endogenous angiotensin II on intrarenal distribution of glomerular filtration rate in rats.
Journal: The Journal of physiology 20020615
Title: Savignygrin, a platelet aggregation inhibitor from the soft tick Ornithodoros savignyi, presents the RGD integrin recognition motif on the Kunitz-BPTI fold.
Journal: The Journal of biological chemistry 20020614
Title: Elastase release following myocardial ischemia during extracorporeal circulation (ECC) -- marker of ongoing systemic inflammation?
Journal: The Thoracic and cardiovascular surgeon 20020601
Title: Aprotinin in coronary operation with cardiopulmonary bypass: does 'low-dose' aprotinin inhibit the inflammatory response?
Journal: The Annals of thoracic surgery 20020601
Title: [Colorimetric determination of sulfite in 'kanpyo' (dried gourd shavings) and 'konnyakuseiko' (devil's-tongue fine powder) using sulfite oxidase and catalase].
Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020601
Title: Carbon-13 NMR shielding in the twenty common amino acids: comparisons with experimental results in proteins.
Journal: Journal of the American Chemical Society 20020515
Title: [Risk factors for latex allergy. Diagnostic methods for aprotinin allergy].
Journal: Annales francaises d'anesthesie et de reanimation 20020501
Title: Aprotinin and deep hypothermic cardiopulmonary bypass with or without circulatory arrest for craniotomy.
Journal: Journal of neurosurgical anesthesiology 20020401
Title: Analysis of serine proteinase-inhibitor interaction by alanine shaving.
Journal: Protein science : a publication of the Protein Society 20020401
Title: Thermodynamics of single peptide bond cleavage in bovine pancreatic trypsin inhibitor (BPTI).
Journal: Protein science : a publication of the Protein Society 20020401
Title: Synthesis of a Kunitz-type serine proteinase inhibitory protein that shares homology with bovine pancreatic trypsin inhibitor by ovine intervertebral disc cells in serum-free alginate bead culture.
Journal: Journal of spinal disorders & techniques 20020401
Title: Serine protease activity in m-1 cortical collecting duct cells.
Journal: Hypertension (Dallas, Tex. : 1979) 20020401
Title: [Randomized controlled trial for the effect of amrinone and aprotinin on expression leukocyte adhesion molecule in patients with prosthetic valve replacement during perioperative period].
Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20020401
Title: Loading into and electro-stimulated release of peptides and proteins from chondroitin 4-sulphate hydrogels.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020301
Title: A clinical study of a fibrinogen-based collagen fleece for dural repair in neurosurgery.
Journal: Acta neurochirurgica 20020301
Title: Peptidase activity on the surface of the porcine buccal mucosa.
Journal: International journal of pharmaceutics 20020221
Title: A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility.
Journal: Biochemistry 20020219
Title: Native-like interactions favored in the unfolded bovine pancreatic trypsin inhibitor have different roles in folding.
Journal: Biochemistry 20020219
Title: Role of kallikrein-kininogen system in insulin-stimulated glucose transport after muscle contractions.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020201
Title: Role of kinins and sensory neurons in the rat pleural leukocyte migration induced by Phoneutria nigriventer spider venom.
Journal: Neuroscience letters 20020201
Title: Evaluation of pKD1-based plasmid systems for heterologous protein production in Kluyveromyces lactis.
Journal: Applied microbiology and biotechnology 20020201
Title: Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor.
Journal: Biochemistry 20020108
Title: Aprotinin and reduced epinephrine requirements in orthotopic liver transplantation.
Journal: Anesthesiology 20020101
Title: Point-of-care testing for prothrombin time, but not activated partial thromboplastin time, correlates with laboratory methods in patients receiving aprotinin or epsilon-aminocaproic acid while undergoing cardiac surgery.
Journal: American journal of clinical pathology 20020101
Title: Matrix metalloproteinase inhibitor BB-3103 unlike the serine proteinase inhibitor aprotinin abrogates epidermal healing of human skin wounds ex vivo.
Journal: The Journal of investigative dermatology 20020101
Title: Model peptide substrates and ligands in analysis of action of mammalian protein disulfide-isomerase.
Journal: Methods in enzymology 20020101
Title: Multi-centre trial of aprotinin [correction of aspirin] highlights increased safety with higher dose.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20020101
Title: Cardioprotective effect of pump prime aprotinin in coronary artery bypass grafting.
Journal: Cardiovascular drugs and therapy 20020101
Title: Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth.
Journal: BMC cancer 20020101
Title: Safety and efficacy of methods for reducing perioperative allogeneic transfusion: a critical review of the literature.
Journal: American journal of therapeutics 20020101
Title: [Protease inhibitors as an anesthetic component in ENT surgery].
Journal: Anesteziologiia i reanimatologiia 20020101
Title: [Prophylactics of acute pancreatitis in pancreatic-duodenal resection].
Journal: Vestnik khirurgii imeni I. I. Grekova 20020101
Title: Selection of potent chymotrypsin and elastase inhibitors from M13 phage library of basic pancreatic trypsin inhibitor (BPTI).
Journal: Biochimica et biophysica acta 20011217
Title: Zinc fingers and thiol-disulfide oxidoreductase activities of chaperone DnaJ.
Journal: Biochemistry 20011211
Title: The effect of aprotinin on ischemia-reperfusion injury in the rabbit kidney.
Journal: Pharmacological research 20011201
Title: Affinity and Western blotting reveal homologies between ovine intervertebral disc serine proteinase inhibitory proteins and bovine pancreatic trypsin inhibitor.
Journal: Proteomics 20011201
Title: Amino acid sequence of a trypsin inhibitor from a Spirometra (Spirometra erinaceieuropaei).
Journal: Biological & pharmaceutical bulletin 20011201
Title: CPMG sequences with enhanced sensitivity to chemical exchange.
Journal: Journal of biomolecular NMR 20011201
Title: Mast cell tryptases and airway remodeling.
Journal: American journal of respiratory and critical care medicine 20011115
Title: NMR studies of protein surface accessibility.
Journal: The Journal of biological chemistry 20011109
Title: Protein unfolding during reversed-phase chromatography: II. Role of salt type and ionic strength.
Journal: Biotechnology and bioengineering 20011101
Title: The effects of aprotinin on thromboelastography with three different activators.
Journal: Anesthesiology 20011101
Title: New antiinflammatory and platelet-preserving effects of aprotinin.
Journal: The Annals of thoracic surgery 20011101
Title: Attenuation of neurologic injury during cardiac surgery.
Journal: The Annals of thoracic surgery 20011101
Title: The use of technologies to decrease peri-operative allogenic blood transfusion: results of practice variation in Israel.
Journal: The Israel Medical Association journal : IMAJ 20011101
Title: Mutational analysis of hydrogen bonding residues in the BPTI folding pathway.
Journal: Journal of molecular biology 20011026
Title: Improved synthesis of C-terminal peptide thioesters on 'safety-catch' resins using LiBr/THF.
Journal: Organic letters 20011004
Title: Vineberg procedure combined with therapeutic angiogenesis: old wine in a new bottle.
Journal: The Annals of thoracic surgery 20011001
Title: The effects of aprotinin and steroids on generation of cytokines during coronary artery surgery.
Journal: Journal of cardiothoracic and vascular anesthesia 20011001
Title: Pressure-stability of phospholipid bicelles: measurement of residual dipolar couplings under extreme conditions.
Journal: Journal of biomolecular NMR 20011001
Title: Effects of methylprednisolone and aprotinin on phospholipase D activity of leukocytes in systemic inflammatory response induced by cardiopulmonary bypass.
Journal: Acta pharmacologica Sinica 20011001
Title: Aprotinin but not epsilon-aminocaproic acid decreases interleukin-10 after cardiac surgery with extracorporeal circulation: randomized, double-blind, placebo-controlled study in patients receiving aprotinin and epsilon-aminocaproic acid.
Journal: Circulation 20010918
Title: Aprotinin, blood loss, and renal dysfunction in deep hypothermic circulatory arrest.
Journal: Circulation 20010918
Title: Electron spin resonance and fluorescence studies of the bound-state conformation of a model protein substrate to the chaperone SecB.
Journal: The Journal of biological chemistry 20010907
Title: Lipopolysaccharide-induced subsensitivity of protease-activated receptor-2 in the mouse salivary glands in vivo.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010901
Title: Low-dose postoperative aprotinin reduces mediastinal drainage and blood product use in patients undergoing primary coronary artery bypass grafting who are taking aspirin: a prospective, randomized, double-blind, placebo-controlled trial.
Journal: The Journal of thoracic and cardiovascular surgery 20010901
Title: Systemic inflammation and cardiac surgery: an update.
Journal: Perfusion 20010901
Title: Aprotinin: is it prothrombotic?
Journal: Perfusion 20010901
Title: Antifibrinolytic agents and desmopressin as hemostatic agents in cardiac surgery.
Journal: The Annals of pharmacotherapy 20010901
Title: Plasmin-independent gelatinase B (matrix metalloproteinase-9) release by monocytes under the influence of urokinase.
Journal: Biochemistry. Biokhimiia 20010901
Title: Mutation of yeast Eug1p CXXS active sites to CXXC results in a dramatic increase in protein disulphide isomerase activity.
Journal: The Biochemical journal 20010815
Title: NMR-detected order in core residues of denatured bovine pancreatic trypsin inhibitor.
Journal: Biochemistry 20010814
Title: Postoperatively administered aprotinin or epsilon aminocaproic acid after cardiopulmonary bypass has limited benefit.
Journal: The Annals of thoracic surgery 20010801
Title: Effect of aprotinin on endothelial cell activation.
Journal: The Journal of thoracic and cardiovascular surgery 20010701
Title: Anaphylactic reactions to aprotinin reexposure in cardiac surgery: relation to antiaprotinin immunoglobulin G and E antibodies.
Journal: Anesthesiology 20010701
Title: Characterization of a serine protease that cleaves pro-gamma-melanotropin at the adrenal to stimulate growth.
Journal: Cell 20010629
Title: Electrostatic effects play a central role in cold adaptation of trypsin.
Journal: FEBS letters 20010615
Title: Activation of epithelial sodium channels by prostasin in Xenopus oocytes.
Journal: Journal of the American Society of Nephrology : JASN 20010601
Title: Aprotinin impairs endothelium-dependent relaxation in rat aorta and inhibits nitric oxide release from rat coronary endothelial cells.
Journal: Cardiovascular research 20010601
Title: The use of fibrin beads for tissue engineering and subsequential transplantation.
Journal: Tissue engineering 20010601
Title: [Randomized controlled trial for the effect of amrinone and aprotinin on proinflammatory cytokine release in patients with prosthetic valve replacement during perioperative period].
Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010601
Title: High-level bacterial expression and 15N-alanine-labeling of bovine trypsin. Application to the study of trypsin-inhibitor complexes and trypsinogen activation by NMR spectroscopy.
Journal: Biochemistry 20010529
Title: The efficacy of antifibrinolytics in the reduction of blood loss during complex adult reconstructive spine surgery.
Journal: Spine 20010515
Title: Discrimination between native and non-native disulfides by protein-disulfide isomerase.
Journal: The Journal of biological chemistry 20010511
Title: Release of biologically active TGF-beta from airway smooth muscle cells induces autocrine synthesis of collagen.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010501
Title: Possible involvement of EBV-mediated alpha-fodrin cleavage for organ-specific autoantigen in Sjogren's syndrome.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010501
Title: Na(+)/H(+)-exchange inhibition and aprotinin administration: promising tools for myocardial protection during minimally invasive CABG.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20010501
Title: A genetically engineered human Kunitz protease inhibitor with increased kallikrein inhibition in an ovine model of cardiopulmonary bypass.
Journal: Perfusion 20010501
Title: Immune-complex assays for tyrosine protein kinases.
Journal: Current protocols in immunology 20010501
Title: Fibrin gel -- advantages of a new scaffold in cardiovascular tissue engineering.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20010401
Title: An electrospray ionization mass spectrometry investigation of 1-anilino-8-naphthalene-sulfonate (ANS) binding to proteins.
Journal: Journal of the American Society for Mass Spectrometry 20010401
Title: Pharmacological strategies for blood conservation in cardiac surgery: erythropoietin and antifibrinolytics.
Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20010401
Title: Cellular pathology of atherosclerosis: smooth muscle cells prime cocultured endothelial cells for enhanced leukocyte adhesion.
Journal: Circulation research 20010330
Title: Parenteral water/oil emulsions containing hydrophilic compounds with enhanced in vivo retention: formulation, rheological characterisation and study of in vivo fate using whole body gamma-scintigraphy.
Journal: International journal of pharmaceutics 20010314
Title: Sustained elevated plasma aprotinin concentration in mice following intraperitoneal injections of w/o emulsions incorporating aprotinin.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20010312
Title: Two mutants of human heparin binding protein (CAP37): toward the understanding of the nature of lipid A/LPS and BPTI binding.
Journal: Proteins 20010301
Title: Regional hemostatic status and blood requirements after total knee arthroplasty with and without tranexamic acid or aprotinin.
Journal: Anesthesia and analgesia 20010301
Title: Structure, localization and potential role of a novel molluscan trypsin inhibitor in Lymnaea.
Journal: European journal of biochemistry 20010301
Title: Comparison of epsilon aminocaproic acid and low-dose aprotinin in cardiopulmonary bypass: efficiency, safety and cost.
Journal: The Annals of thoracic surgery 20010301
Title: Epsilon-aminocaproic acid promotes the release of alpha2-antiplasmin during and after cardiopulmonary bypass.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20010301
Title: Complexing of basic pancreatic proteinase inhibitor with soybean phospholipid multilamellar vesicles.
Journal: Biochemistry. Biokhimiia 20010301
Title: Leukodepletion and aprotinin improve clinical outcome after extracorporeal circulation.
Journal: Perfusion 20010301
Title: Reduced need for vasopressors in patients receiving aprotinin during orthotopic liver transplantation.
Journal: Anesthesiology 20010301
Title: Regulation of plasminogen binding to neutrophils.
Journal: Blood 20010215
Title: Enhancement of chymotrypsin-inhibitor/substrate interactions by 3 M NaCl.
Journal: Biochimica et biophysica acta 20010209
Title: Regulation of urokinase plasminogen activator/plasmin-mediated invasion of melanoma cells by the integrin vitronectin receptor alphaVbeta3.
Journal: International journal of cancer 20010201
Title: Prolonged stability of endogenous cardiotrophin-1 in whole blood.
Journal: Metabolism: clinical and experimental 20010201
Title: Aprotinin and the systemic inflammatory response after cardiopulmonary bypass.
Journal: The Annals of thoracic surgery 20010201
Title: Pump prime aprotinin fails to limit proinflammatory cytokine release after coronary artery bypass surgery.
Journal: Scandinavian cardiovascular journal : SCJ 20010201
Title: The effect of aprotinin on renal function in orthotopic liver transplantation.
Journal: Transplantation 20010127
Title: Aromatic ring-flipping in supercooled water: implications for NMR-based structural biology of proteins.
Journal: Journal of the American Chemical Society 20010124
Title: Prevention of the adverse effects of aprotinin in autologous fibrin glue.
Journal: Biological & pharmaceutical bulletin 20010101
Title: Ultra-low dose aprotinin decreases transfusion requirements and is cost effective in coronary operations.
Journal: The Annals of thoracic surgery 20010101
Title: Determination of plasma aprotinin levels by functional and immunologic assays.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20010101
Title: Improved early graft survival in patients receiving aprotinin during orthotopic liver transplantation.
Journal: Transplantation proceedings 20010101
Title: Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Journal: The Cochrane database of systematic reviews 20010101
Title: A coculture model of intrahepatic islet transplantation: activation of Kupffer cells by islets and acinar tissue.
Journal: Cell transplantation 20010101
Title: Role of aprotinin in the management of experimental fungal keratitis.
Journal: Ophthalmic research 20010101
Title: [Replacement of the pyrogen-test as batch control test for the biological substances aprotinin and urokinase].
Journal: ALTEX 20010101
Title: Renal tubular peptide catabolism in chronic vascular rejection.
Journal: Renal failure 20010101
Title: Toward new designed proteins derived from bovine pancreatic trypsin inhibitor (BPTI): covalent cross-linking of two 'core modules' by oxime-forming ligation.
Journal: Bioconjugate chemistry 20010101
Title: [Intracellular disorders in the dog myocardium in low cardiac output syndrome caused by massive hemorrhage, approaches to correction].
Journal: Anesteziologiia i reanimatologiia 20010101
Title: Structure-function relationship of serine protease-protein inhibitor interaction.
Journal: Acta biochimica Polonica 20010101
Title: [Special aspects of anesthesiology and intensive care in oncological operations with microsurgical autoplasty].
Journal: Anesteziologiia i reanimatologiia 20010101
Title: [Anesthesiological support of interventions for cancer with intraoperative radio- and hypoxic radiotherapy].
Journal: Anesteziologiia i reanimatologiia 20010101
Title: [Aprotinin (Antilysin Spofa)--its effect on decreasing hemorrhage in the postoperative period in hip arthroplasty].
Journal: Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 20010101
Title: Modulating IL-6 and IL-10 levels by pharmacologic strategies and the impact of different extracorporeal circulation parameters during cardiac surgery.
Journal: Shock (Augusta, Ga.) 20010101
Title: Convulsive seizures following subdural application of fibrin sealant containing tranexamic acid in a rat model.
Journal: Neurosurgery 20001201
Title: Lead stimulates intercellular signalling between hepatocytes and Kupffer cells.
Journal: European journal of pharmacology 20000811
Title: Thrombosis during all-trans-retinoic acid therapy in a child with acute promyelocytic leukemia and factor VQ 506 mutation.
Journal: Pediatric hematology and oncology 20000301
Title: Substance P may attenuate gastric hyperemia by a mast cell-dependent mechanism in the damaged gastric mucosa.
Journal: The American journal of physiology 19991101
Title: Activation of Xenopus eggs by proteases: possible involvement of a sperm protease in fertilization.
Journal: Developmental biology 19990401
Title: Proximal renal tubular peptide catabolism, ammonia excretion and tubular injury in patients with proteinuria: before and after lisinopril.
Journal: Clinical science (London, England : 1979) 19980401
Title: Oral sodium bicarbonate reduces proximal renal tubular peptide catabolism, ammoniogenesis, and tubular damage in renal patients.
Journal: Renal failure 19980301
Title: Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain.
Journal: The Journal of biological chemistry 19971212
Title: Characterization of an insulin-like growth factor binding protein-5 protease produced by rat articular chondrocytes and a neuroblastoma cell line.
Journal: Growth regulation 19960901
Title: Efficacy of serine protease inhibitors against Cryptosporidium parvum infection in a bovine fallopian tube epithelial cell culture system.
Journal: The Journal of parasitology 19960801
Title: Fatal thromboembolism in acute promyelocytic leukaemia treated with a combination of all-trans retinoic acid and aprotonin.
Journal: Clinical and laboratory haematology 19960301
Title: Factor XII fragment and kallikrein generation in plasma during incubation with biomaterials.
Journal: Journal of biomedical materials research 19940301
Title: Substance P attenuates gastric mucosal hyperemia after stimulation of sensory neurons in the rat stomach.
Journal: Gastroenterology 19940201
Title: Chymotrypsinogen: an activating enzyme in the mitochondrial membrane of rat submaxillary gland.
Journal: Biochemistry international 19911201
Title: (K15R M52E) aprotinin is a weak Kunitz-type inhibitor of HIV-1 replication in H9 cells.
Journal: Biomedica biochimica acta 19910101
Title: [Human fibrin glue as a new therapeutic concept in cyclophosphamide-induced cystitis and macrohematuria].
Journal: Klinische Padiatrie 19880101
Title: Fibrinogen induces adhesion, spreading, and microfilament organization of human endothelial cells in vitro.
Journal: The Journal of cell biology 19870501
Title: Fate of porcine and human insulin at the subcutaneous injection site. II. In vitro degradation of insulins in the subcutaneous tissue of the rat.
Journal: Journal of pharmacobio-dynamics 19850101
Title: Role of the prostaglandin and kallikrein-kinin systems in aminoglycoside-induced acute renal failure.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 19850101
Title: Enhancement of eosinophil effector function by soluble factors released by S. mansoni: role of proteases.
Journal: Journal of immunology (Baltimore, Md. : 1950) 19830701
Title: Pharmaceutical approach to subcutaneous dosage forms of insulin.
Journal: Journal of pharmaceutical sciences 19830401
Title: Chemotactic activity in the coronary sinus after experimental myocardial infarction: effects of pharmacologic interventions on ischemic injury.
Journal: The American journal of cardiology 19771001
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