Title: Agonistic effects of diverse xenobiotics on the constitutive androstane receptor as detected in a recombinant yeast-cell assay.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180201
Title: Association of organochlorine pesticides with the mRNA expression of tumour necrosis factor-alpha (TNF-α) & cyclooxygenase-2 (COX-2) genes in idiopathic preterm birth.
Journal: The Indian journal of medical research 20160601
Title: Development of a recombinant human ovarian (BG1) cell line containing estrogen receptor α and β for improved detection of estrogenic/antiestrogenic chemicals.
Journal: Environmental toxicology and chemistry 20160101
Title: Identification of California Condor Estrogen Receptors 1 and 2 and Their Activation by Endocrine Disrupting Chemicals.
Journal: Endocrinology 20151201
Title: Effects of adrenolytic mitotane on drug elimination pathways assessed in vitro.
Journal: Endocrine 20150801
Title: Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome.
Journal: European journal of endocrinology 20150601
Title: Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150201
Title: FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.
Journal: Chemico-biological interactions 20130905
Title: Mutational analyses of epidermal growth factor receptor and downstream pathways in adrenocortical carcinoma.
Journal: European journal of endocrinology 20130701
Title: Interferon-β is a potent inhibitor of cell growth and cortisol production in vitro and sensitizes human adrenocortical carcinoma cells to mitotane.
Journal: Endocrine-related cancer 20130601
Title: Influence of the CYP2B6 polymorphism on the pharmacokinetics of mitotane.
Journal: Pharmacogenetics and genomics 20130601
Title: Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells.
Journal: Endocrine-related cancer 20130601
Title: Enantioselective induction of cytotoxicity by o,p'-DDD in PC12 cells: implications of chirality in risk assessment of POPs metabolites.
Journal: Environmental science & technology 20130416
Title: Mitotane induces CYP3A4 expression via activation of the steroid and xenobiotic receptor.
Journal: The Journal of endocrinology 20130301
Title: The effect of mitotane on viability, steroidogenesis and gene expression in NCI‑H295R adrenocortical cells.
Journal: Molecular medicine reports 20130301
Title: Simultaneous analysis of mitotane and its main metabolites in human blood and urine samples by SPE-HPLC technique.
Journal: Biomedical chromatography : BMC 20121101
Title: Differential effect of DDT, DDE, and DDD on COX-2 expression in the human trophoblast derived HTR-8/SVneo cells.
Journal: Journal of biochemical and molecular toxicology 20121101
Title: [Surgery of the adrenal gland].
Journal: Nihon Geka Gakkai zasshi 20121101
Title: Efficiency and tolerance of mitotane in Cushing's disease in 76 patients from a single center.
Journal: European journal of endocrinology 20121001
Title: Sunitinib in refractory adrenocortical carcinoma: a phase II, single-arm, open-label trial.
Journal: The Journal of clinical endocrinology and metabolism 20121001
Title: The organochlorine o,p'-DDT plays a role in coactivator-mediated MAPK crosstalk in MCF-7 breast cancer cells.
Journal: Environmental health perspectives 20120901
Title: Effects of mitotane on gene expression in the adrenocortical cell line NCI-H295R: a microarray study.
Journal: Pharmacogenomics 20120901
Title: Mitotane exhibits dual effects on steroidogenic enzymes gene transcription under basal and cAMP-stimulating microenvironments in NCI-H295 cells.
Journal: Toxicology 20120816
Title: The next generation of therapies for adrenocortical cancers.
Journal: Trends in endocrinology and metabolism: TEM 20120701
Title: Structural requirements for mitotane activity: development of analogs for treatment of adrenal cancer.
Journal: Anticancer research 20120701
Title: Ribonucleotide reductase large subunit (RRM1) gene expression may predict efficacy of adjuvant mitotane in adrenocortical cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120615
Title: Combination chemotherapy in advanced adrenocortical carcinoma.
Journal: The New England journal of medicine 20120607
Title: [German adrenocortical carcinoma registry. Surgical therapy results and follow-up treatment].
Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20120601
Title: Surgical aspects in the treatment of adrenocortical carcinomas in children: data of the GPOH-MET 97 trial.
Journal: Klinische Padiatrie 20120401
Title: Xenograft models for preclinical drug testing: implications for adrenocortical cancer.
Journal: Molecular and cellular endocrinology 20120331
Title: Organochlorine pesticides and polychlorinated biphenyls in sediments and fish from freshwater cultured fish ponds in different agricultural contexts in north-eastern France.
Journal: Ecotoxicology and environmental safety 20120301
Title: Mitotane treatment for adrenocortical carcinoma: an overview.
Journal: Minerva endocrinologica 20120301
Title: High-dose mitotane strategy in adrenocortical carcinoma: prospective analysis of plasma mitotane measurement during the first 3 months of follow-up.
Journal: European journal of endocrinology 20120201
Title: Advances in medical therapies for Cushing's syndrome.
Journal: Discovery medicine 20120201
Title: Preclinical investigation of nanoparticle albumin-bound paclitaxel as a potential treatment for adrenocortical cancer.
Journal: Annals of surgery 20120101
Title: Assessment of salivary free cortisol levels by liquid chromatography with tandem mass spectrometry (LC-MS/MS) in patients treated with mitotane.
Journal: Hormones (Athens, Greece) 20120101
Title: Metronomic therapy concepts in the management of adrenocortical carcinoma.
Journal: Hormones & cancer 20111201
Title: Therapeutic management of advanced adrenocortical carcinoma: what do we know in 2011?
Journal: Hormones & cancer 20111201
Title: Targeted therapies for adrenocortical carcinoma: IGF and beyond.
Journal: Hormones & cancer 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Contemporary management of adrenocortical carcinoma.
Journal: European urology 20111101
Title: Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma.
Journal: Clinical endocrinology 20111101
Title: Chemotherapy for advanced adrenal cancer: improvement from a molecular approach?
Journal: BJU international 20111101
Title: Metastatic adrenocortical carcinoma presenting simultaneously with Cushing's and Conn's syndromes: a case report.
Journal: Japanese journal of clinical oncology 20111101
Title: [Adrenocortical carcinomas: therapeutic advances in 2011].
Journal: Annales d'endocrinologie 20111001
Title: [Mitotane as possible cause of acute intermittent porphyria].
Journal: Ugeskrift for laeger 20110912
Title: Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome.
Journal: The Journal of clinical endocrinology and metabolism 20110901
Title: A simple HPLC method for plasma level monitoring of mitotane and its two main metabolites in adrenocortical cancer patients.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110801
Title: Enhancement of dissolution rate of mitotane and warfarin prepared by using microemulsion systems.
Journal: Colloids and surfaces. B, Biointerfaces 20110701
Title: Plasma concentrations of o,p'DDD, o,p'DDA, and o,p'DDE as predictors of tumor response to mitotane in adrenocortical carcinoma: results of a retrospective ENS@T multicenter study.
Journal: The Journal of clinical endocrinology and metabolism 20110601
Title: Thyroid effects and anticancer treatment.
Journal: Annales d'endocrinologie 20110601
Title: Surgical resection of a virilizing adrenal mass with extensive tumor thrombus.
Journal: The Canadian journal of urology 20110601
Title: Changes in retinol-binding protein concentrations and thyroid homeostasis with nonoccupational exposure to DDT.
Journal: Environmental health perspectives 20110501
Title: [Management of adrenocortical carcinomas in children].
Journal: Bulletin du cancer 20110501
Title: Mitotane has a strong and a durable inducing effect on CYP3A4 activity.
Journal: European journal of endocrinology 20110401
Title: Determination of n-octanol/water partition coefficient for DDT-related compounds by RP-HPLC with a novel dual-point retention time correction.
Journal: Chemosphere 20110301
Title: A comparison of factors that influence survival in dogs with adrenal-dependent hyperadrenocorticism treated with mitotane or trilostane.
Journal: Journal of veterinary internal medicine 20110101
Title: Pregnancy in a patient with adrenocortical carcinoma during treatment with Mitotane - a case report.
Journal: Endokrynologia Polska 20110101
Title: Normal adrenal function in an infant following a pregnancy complicated by maternal adrenal cortical carcinoma and mitotane exposure.
Journal: Journal of pediatric endocrinology & metabolism : JPEM 20110101
Title: High (18)F-FDG uptake by the remaining adrenal gland four months after surgery and initiation of mitotane treatment in two patients with adrenocortical carcinoma.
Journal: Hellenic journal of nuclear medicine 20110101
Title: Practical considerations in the evaluation and management of adrenocortical cancer.
Journal: Seminars in oncology 20101201
Title: Androgen- and estrogen-secreting adrenal cancers.
Journal: Seminars in oncology 20101201
Title: Improved survival in patients with stage II adrenocortical carcinoma followed up prospectively by specialized centers.
Journal: The Journal of clinical endocrinology and metabolism 20101101
Title: What is the best approach to an apparently nonmetastatic adrenocortical carcinoma?
Journal: Clinical endocrinology 20101101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Prognostic markers of survival after combined mitotane- and platinum-based chemotherapy in metastatic adrenocortical carcinoma.
Journal: Endocrine-related cancer 20100901
Title: Mitotane effects in a H295R xenograft model of adjuvant treatment of adrenocortical cancer.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100901
Title: Adjuvant therapy in patients with adrenocortical carcinoma: a position of an international panel.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100810
Title: Mitotane serum level analysis; good agreement between two different assays.
Journal: Clinical endocrinology 20100801
Title: Mitotane sensitizes adrenocortical cancer cells to ionizing radiations by involvement of the cyclin B1/CDK complex in G2 arrest and mismatch repair enzymes modulation.
Journal: International journal of oncology 20100801
Title: Successful therapy of Cushing's disease caused by an extrapituitary parasellar adenoma.
Journal: Clinical endocrinology 20100701
Title: Therapeutic concentrations of mitotane (o,p'-DDD) inhibit thyrotroph cell viability and TSH expression and secretion in a mouse cell line model.
Journal: Endocrinology 20100601
Title: Development of microemulsion of mitotane for improvement of oral bioavailability.
Journal: Drug development and industrial pharmacy 20100401
Title: Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study.
Journal: Clinical endocrinology 20100301
Title: The long-term survival in adrenocortical carcinoma with active surgical management and use of monitored mitotane.
Journal: Endocrine-related cancer 20100301
Title: Chiral effects in adrenocorticolytic action of o,p'-DDD (mitotane) in human adrenal cells.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20100301
Title: Biphasic hormonal responses to the adrenocorticolytic DDT metabolite 3-methylsulfonyl-DDE in human cells.
Journal: Toxicology and applied pharmacology 20100201
Title: Management of Cushing's syndrome due to ectopic adrenocorticotropin secretion with 1,ortho-1, para'-dichloro-diphenyl-dichloro-ethane: findings in 23 patients from a single center.
Journal: The Journal of clinical endocrinology and metabolism 20100201
Title: Recurrence of adrenal cortical carcinoma following resection: surgery alone can achieve results equal to surgery plus mitotane.
Journal: Annals of surgical oncology 20100101
Title: Medical therapy of Cushing's disease: where are we now?
Journal: Frontiers of hormone research 20100101
Title: Management of dyslipidemia in Cushing's syndrome.
Journal: Neuroendocrinology 20100101
Title: Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole.
Journal: Neuroendocrinology 20100101
Title: [Mitotane in the treatment of adrenal carcinoma].
Journal: Duodecim; laaketieteellinen aikakauskirja 20100101
Title: Adrenocortical cancer.
Journal: The Surgical clinics of North America 20091001
Title: Management of endocrine manifestations and the use of mitotane as a chemotherapeutic agent for adrenocortical carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920
Title: How is adrenocortical cancer being managed in the UK?
Journal: Annals of the Royal College of Surgeons of England 20090901
Title: Synthesis of 2-(4-chlorophenyl)-2-(4-chloro-3-thiophenol)-1,1-dichloroethene (3-SH-DDE) via Newman-Kwart rearrangement - a precursor for synthesis of radiolabeled and unlabeled alkylsulfonyl-DDEs.
Journal: Chemosphere 20090801
Title: Management of adrenocortical carcinoma.
Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20090701
Title: Interindividual differences in o,p'-DDD enantiomer kinetics examined in Göttingen minipigs.
Journal: Chemosphere 20090601
Title: Adjuvant mitotane for adrenocortical cancer--working through uncertainty.
Journal: The Journal of clinical endocrinology and metabolism 20090601
Title: Metastatic virilizing adrenocortical carcinoma: a rare case of cure with surgery and mitotane therapy.
Journal: Clinical medicine & research 20090601
Title: Effects of o,p'-DDE, heptachlor, and 17beta-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia, Oreochromis mossambicus.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090501
Title: [The medical management of Cushing's syndrome].
Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20090401
Title: Metastatic adrenocortical carcinoma treated with sunitinib: a case report.
Journal: Japanese journal of clinical oncology 20090301
Title: The imaging diagnosis of pulmonary thromboembolism.
Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20090201
Title: Pneumothorax secondary to pulmonary thromboembolism in a dog.
Journal: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) 20090201
Title: (2S)-1,1-Dichloro-2-(2-chloro-phen-yl)-2-(4-chloro-phen-yl)ethane.
Journal: Acta crystallographica. Section E, Structure reports online 20090201
Title: Organochlorine-mediated potentiation of the general coactivator p300 through p38 mitogen-activated protein kinase.
Journal: Carcinogenesis 20090101
Title: Preclinical targeting of the type I insulin-like growth factor receptor in adrenocortical carcinoma.
Journal: The Journal of clinical endocrinology and metabolism 20090101
Title: Adrenocortical cancer treatment.
Journal: Hormone research 20090101
Title: Cushing's disease in dogs and humans.
Journal: Hormone research 20090101
Title: Prospective evaluation of mitotane toxicity in adrenocortical cancer patients treated adjuvantly.
Journal: Endocrine-related cancer 20081201
Title: A patient with ectopic cortisol production derived from malignant testicular masses.
Journal: Nature clinical practice. Endocrinology & metabolism 20081201
Title: Adjuvant mitotane for adrenocortical cancer--a recurring controversy.
Journal: The Journal of clinical endocrinology and metabolism 20081001
Title: Emerging drugs for adrenocortical carcinoma.
Journal: Expert opinion on emerging drugs 20080901
Title: Bilateral primary adrenal non-Hodgkin's lymphoma and primary adrenocortical carcinoma--review of the literature preoperative differentiation of adrenal tumors.
Journal: Endocrine journal 20080801
Title: Impact of standardised reporting in adrenocortical carcinoma: a single centre clinicopathological review.
Journal: Journal of clinical pathology 20080801
Title: Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.
Journal: The Journal of clinical endocrinology and metabolism 20080701
Title: Systemic chemotherapy for adrenocortical carcinoma: comparative responses to conventional first-line therapies.
Journal: Anti-cancer drugs 20080701
Title: Adjunctive treatment of adrenocortical carcinoma.
Journal: Current opinion in endocrinology, diabetes, and obesity 20080601
Title: Mitotane increases the radiotherapy inhibitory effect and induces G2-arrest in combined treatment on both H295R and SW13 adrenocortical cell lines.
Journal: Endocrine-related cancer 20080601
Title: A novel pretreatment approach for fast determination of organochlorine pesticides in biotic samples.
Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20080501
Title: Percutaneous laser ablation of unresectable primary and metastatic adrenocortical carcinoma.
Journal: European journal of radiology 20080401
Title: [Management of hypercortisolism].
Journal: La Revue de medecine interne 20080401
Title: Modulation of proteomic profile in H295R adrenocortical cell line induced by mitotane.
Journal: Endocrine-related cancer 20080301
Title: A young woman with a severe bilateral pneumonia as the presenting sign of an adrenal carcinoma.
Journal: The Netherlands journal of medicine 20080301
Title: Pharmacokinetics of the adrenocorticolytic compounds 3-methylsulphonyl-DDE and o,p'-DDD (mitotane) in Minipigs.
Journal: Cancer chemotherapy and pharmacology 20080201
Title: [Adrenocortical carcinoma. Diagnostic work-up and treatment].
Journal: Der Urologe. Ausg. A 20080201
Title: Successful treatment of adrenocortical carcinoma with pulmonary metastasis in a child: report of a case.
Journal: Surgery today 20080101
Title: Comparison of non-selective adrenocorticolysis with mitotane or trilostane for the treatment of dogs with pituitary-dependent hyperadrenocorticism.
Journal: The Veterinary record 20071215
Title: Response to mitotane predicts outcome in patients with recurrent adrenal cortical carcinoma.
Journal: Surgery 20071201
Title: DDT- and DDE-induced disruption of ovarian steroidogenesis in prepubertal porcine ovarian follicles: a possible interaction with the main steroidogenic enzymes and estrogen receptor beta.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20071201
Title: Comparative CYP-dependent binding of the adrenocortical toxicants 3-methylsulfonyl-DDE and o,p'-DDD in Y-1 adrenal cells.
Journal: Archives of toxicology 20071101
Title: Pharmacological management of Cushing's syndrome: an update.
Journal: Arquivos brasileiros de endocrinologia e metabologia 20071101
Title: Adjuvant mitotane in adrenocortical carcinoma.
Journal: The New England journal of medicine 20070920
Title: Adjuvant mitotane in adrenocortical carcinoma.
Journal: The New England journal of medicine 20070920
Title: Adjuvant mitotane in adrenocortical carcinoma.
Journal: The New England journal of medicine 20070920
Title: Adjuvant mitotane in adrenocortical carcinoma.
Journal: The New England journal of medicine 20070920
Title: Tailored hormonal therapy in secretory adrenocortical cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070701
Title: Adjuvant mitotane treatment for adrenocortical carcinoma.
Journal: The New England journal of medicine 20070607
Title: Adjuvant mitotane therapy of adrenal cancer - use and controversy.
Journal: The New England journal of medicine 20070607
Title: The unique case of adrenocortical malignant and functioning oncocytic tumour.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20070601
Title: [Cushing syndrome].
Journal: Revue de l'infirmiere 20070401
Title: Attenuation of the glucocorticoid response during Ad5IL-12 adenovirus vector treatment enhances natural killer cell-mediated killing of MHC class I-negative LNCaP prostate tumors.
Journal: Cancer research 20070301
Title: Adrenocortical cancer: pathophysiology and clinical management.
Journal: Endocrine-related cancer 20070301
Title: Hyperadrenocorticism: treating dogs.
Journal: Compendium (Yardley, PA) 20070301
Title: Adrenocortical carcinoma.
Journal: The Netherlands journal of medicine 20070201
Title: Long QT syndrome under mitotane therapy.
Journal: Journal of endocrinological investigation 20070201
Title: Medical management of pituitary-dependent hyperadrenocorticism: mitotane versus trilostane.
Journal: Clinical techniques in small animal practice 20070201
Title: Cortisol as a possible marker of metastatic adrenocortical carcinoma: a case report with 3-year follow-up.
Journal: Anticancer research 20070101
Title: Effect of o,p'-DDD and Li+ on apoptotic DNA fragmentation in conventionally normal and tumour tissues of human adrenal cortex.
Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101
Title: Efficacy of adjuvant radiotherapy of the tumor bed on local recurrence of adrenocortical carcinoma.
Journal: The Journal of clinical endocrinology and metabolism 20061101
Title: Effect of mitotane on pituitary corticotrophs in clinically normal dogs.
Journal: American journal of veterinary research 20060801
Title: Dendritic cells as potential adjuvant for immunotherapy in adrenocortical carcinoma.
Journal: Clinical endocrinology 20060801
Title: Mitotane associated with cisplatin, etoposide, and doxorubicin in advanced childhood adrenocortical carcinoma: mitotane monitoring and tumor regression.
Journal: Journal of pediatric hematology/oncology 20060801
Title: Clinical and biological features in the prognosis of adrenocortical cancer: poor outcome of cortisol-secreting tumors in a series of 202 consecutive patients.
Journal: The Journal of clinical endocrinology and metabolism 20060701
Title: A new simple HPLC method for measuring mitotane and its two principal metabolites Tests in animals and mitotane-treated patients.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060606
Title: Mitotane has an estrogenic effect on sex hormone-binding globulin and corticosteroid-binding globulin in humans.
Journal: The Journal of clinical endocrinology and metabolism 20060601
Title: Long-term disease free survival in a patient with metastatic adreno-cortical carcinoma after complete pathological response to chemotherapy plus mitotane.
Journal: Journal of endocrinological investigation 20060601
Title: [Deoxycorticosterone-producing adrenal tumor].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528
Title: [Selective hypoaldosteronism].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528
Title: [Virilizing adrenocortical tumor].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528
Title: [Feminizing adrenocortical tumor].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528
Title: [Adrenocortical carcinoma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060528
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Rapid effects of pesticides on human granulosa-lutein cells.
Journal: Reproduction (Cambridge, England) 20060201
Title: Adrenocortical carcinoma.
Journal: Current opinion in oncology 20060101
Title: Acute hepatopathy associated with mitotane administration in a dog.
Journal: Journal of the American Animal Hospital Association 20060101
Title: [Normalisation of contralateral adrenal function after long-term mitotane therapy in a girl after surgical treatment of adrenocortical carcinoma].
Journal: Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych 20060101
Title: A case of adrenal gland dependent hyperadrenocorticism with mitotane therapy in a Yorkshire terrier dog.
Journal: Journal of veterinary science 20051201
Title: Biology, clinical characteristics, and management of adrenocortical tumors in children.
Journal: Pediatric blood & cancer 20050901
Title: Etoposide, doxorubicin and cisplatin plus mitotane in the treatment of advanced adrenocortical carcinoma: a large prospective phase II trial.
Journal: Endocrine-related cancer 20050901
Title: Clinical features and immunoexpression of p53, MIB-1 and proliferating cell nuclear antigen in adrenal neoplasms.
Journal: The Journal of urology 20050601
Title: Corticosterone- and aldosterone-secreting adrenocortical tumor in a dog.
Journal: Journal of the American Veterinary Medical Association 20050515
Title: [A long term survival of the patient treated due to advanced adrenocortical carcinoma].
Journal: Polskie Archiwum Medycyny Wewnetrznej 20050501
Title: Mitotane for adrenocortical carcinoma treatment.
Journal: Current opinion in investigational drugs (London, England : 2000) 20050401
Title: [Recurrent operations on the adrenal glands].
Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20050301
Title: [Practical use of o,p'DDD in adrenocortical carcinoma].
Journal: Bulletin du cancer 20050301
Title: A six month mitotane course induced sustained correction of hypercortisolism in a young woman with PPNAD and Carney complex.
Journal: Journal of endocrinological investigation 20050101
Title: A comparison of the survival times of dogs treated with mitotane or trilostane for pituitary-dependent hyperadrenocorticism.
Journal: Journal of veterinary internal medicine 20050101
Title: Clinical role of determination of plasma mitotane and its metabolites levels in patients with adrenal cancer: results of a long-term follow-up.
Journal: Journal of experimental therapeutics & oncology 20050101
Title: [Chloditane therapy of adrenocortical cancer].
Journal: Likars'ka sprava 20041201
Title: Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane.
Journal: Veterinary dermatology 20041001
Title: Oncocytic adrenocortical carcinoma.
Journal: Urology 20040801
Title: [Thyroid metastases of an adrenocortical carcinoma 41 years after the diagnosis of the primary tumor].
Journal: Annales de pathologie 20040601
Title: [Diagnosis and treatment for adrenocortical carcinoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040301
Title: [Histoculture drug response assay guided concurrent chemoradiotherapy for lung metastasis from adrenocortical carcinoma--a case report].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040301
Title: [Adrenocortical carcinoma and its treatment].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20040226
Title: Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors.
Journal: Analytical and bioanalytical chemistry 20040201
Title: [Analysis of postoperative recurrence of malignant tumors of adrenal glands].
Journal: Klinichna khirurhiia 20040201
Title: Effect of single and repeated in vitro exposure of ovarian follicles to o,p'-DDT and p,p'-DDT and their metabolites.
Journal: Polish journal of pharmacology 20040101
Title: Toxicity of o,p'-DDE to medaka d-rR strain after a one-time embryonic exposure by in ovo nanoinjection: an early through juvenile life cycle assessment.
Journal: Chemosphere 20031201
Title: [Features of clinical presentation of malignant adrenocortical tumor cortex metabolism over time].
Journal: Likars'ka sprava 20031201
Title: Short-term exposure of Chinook salmon (Oncoryhnchus tshawytscha) to o,p-DDE or DMSO during early life-history stages causes long-term humoral immunosuppression.
Journal: Environmental health perspectives 20031001
Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Journal: Chemical research in toxicology 20031001
Title: Differential mechanisms for regulation of the stress response across latitudinal gradients.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030901
Title: The organochlorine o,p'-DDD disrupts the adrenal steroidogenic signaling pathway in rainbow trout (Oncorhynchus mykiss).
Journal: Toxicology and applied pharmacology 20030801
Title: Pigmentary retinopathy, macular oedema, and abnormal ERG with mitotane treatment.
Journal: The British journal of ophthalmology 20030401
Title: Irreversible binding of o,p'-DDD in interrenal cells of Atlantic cod (Gadus morhua).
Journal: Chemosphere 20030301
Title: In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes).
Journal: Environmental health perspectives 20030101
Title: [Surgical strategy in the treatment of adrenal cortex cancer. Expanded and repeated interventions].
Journal: Annali italiani di chirurgia 20030101
Title: Medical treatment of hyperadrenocorticism in the dog.
Journal: Australian veterinary journal 20030101
Title: Investigation of the role of aldosterone in hypertension associated with spontaneous pituitary-dependent hyperadrenocorticism in dogs.
Journal: The Journal of small animal practice 20021101
Title: Long-term (15 years) outcome in an infant with metastatic adrenocortical carcinoma.
Journal: The Journal of clinical endocrinology and metabolism 20021001
Title: Development of a fish reporter gene system for the assessment of estrogenic compounds and sewage treatment plant effluents.
Journal: Environmental toxicology and chemistry 20020901
Title: Loss of capacity to elevate plasma cortisol in rainbow trout (Oncorhynchus mykiss) treated with a single injection of o,p'-dichlorodiphenyldichloroethane.
Journal: Environmental toxicology and chemistry 20020801
Title: A phase II trial of combination chemotherapy and surgical resection for the treatment of metastatic adrenocortical carcinoma: continuous infusion doxorubicin, vincristine, and etoposide with daily mitotane as a P-glycoprotein antagonist.
Journal: Cancer 20020501
Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
Journal: The Journal of biological chemistry 20020419
Title: [Adrenal crisis due to mitotane therapy].
Journal: Medicina clinica 20020302
Title: Cytochrome P450-catalyzed binding of 3-methylsulfonyl-DDE and o,p'-DDD in human adrenal zona fasciculata/reticularis.
Journal: The Journal of clinical endocrinology and metabolism 20020301
Title: Combined corneal lipid and calcium degeneration in a dog with hyperadrenocorticism: a case report.
Journal: Veterinary ophthalmology 20020301
Title: Cushing's syndrome in children and adolescents: current diagnostic and therapeutic strategies.
Journal: Journal of endocrinological investigation 20020201
Title: Determination of chiral ratio of o,p-DDT and o,p-DDD pesticides on polysaccharides chiral stationary phases by HPLC under reversed-phase mode.
Journal: Environmental toxicology 20020101
Title: Hyperadrenocorticism associated with excessive sex hormone production by an adrenocortical tumor in two dogs.
Journal: Journal of the American Veterinary Medical Association 20011215
Title: [Adrenocortical carcinoma].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20011101
Title: Influence of o'p-DDD on the physiological response to stress in Arctic charr (Salvelinus alpinus).
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20011001
Title: Impact of monitoring plasma 1,1-dichlorodiphenildichloroethane (o,p'DDD) levels on the treatment of patients with adrenocortical carcinoma.
Journal: Cancer 20010915
Title: Medical treatment of canine pituitary-dependent hyperadrenocorticism (Cushing's disease).
Journal: The Veterinary clinics of North America. Small animal practice 20010901
Title: Adrenocortical carcinoma. Clinical outcome at the end of the 20th century.
Journal: Cancer 20010901
Title: Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis.
Journal: Toxicology 20010828
Title: Adrenal cortical carcinoma.
Journal: Current treatment options in oncology 20010801
Title: [Therapy of the adrenocortical carcinoma with Lysodren (o,p'-DDD). Therapeutic management by monitoring o,p'-DDD blood levels].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20010715
Title: Adrenocortical carcinomas: surgical trends and results of a 253-patient series from the French Association of Endocrine Surgeons study group.
Journal: World journal of surgery 20010701
Title: Cytotoxic treatment of adrenocortical carcinoma.
Journal: World journal of surgery 20010701
Title: Molecular and pharmacological evidence for modulation of kinin B(1) receptor expression by endogenous glucocorticoids hormones in rats.
Journal: British journal of pharmacology 20010101
Title: Mitotane-induced febrile pancytopenia: a first case report in paraneoplastic Cushing's syndrome.
Journal: European journal of endocrinology 20010101
Title: Sustained remission of metastatic adrenal carcinoma during long-term administration of low-dose mitotane.
Journal: Journal of endocrinological investigation 20010101
Title: [Changes in metabolism of sialoglycoproteins of the rat stomach during long-term immobilization stress and glucocorticoid hormone deficiency].
Journal: Voprosy meditsinskoi khimii 20010101
Title: Streptozocin and o,p'DDD in the treatment of adrenocortical cancer patients: long-term survival in its adjuvant use.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20001001
Title: Decreased cortisol secretion by adrenal glands perfused with the P-glycoprotein inhibitor valspodar and mitotane or doxorubicin.
Journal: Anti-cancer drugs 20000401
Title: Reporter cell lines to study the estrogenic effects of xenoestrogens.
Journal: The Science of the total environment 19990815
Title: Growth stimulation of a rat pituitary cell line MtT/E-2 by environmental estrogens in vitro and in vivo.
Journal: Endocrine journal 19990801
Title: Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers.
Journal: Toxicology and applied pharmacology 19990215
Title: Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
Journal: Toxicology and applied pharmacology 19980701
Title: A patient with adrenocortical carcinoma: characterization of its biological activity and drug resistance profile.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19970301
Title: Interaction of environmental chemicals with the estrogen and progesterone receptors from the oviduct of the American alligator.
Journal: Environmental health perspectives 19961201
Title: Identification of environmental chemicals with estrogenic activity using a combination of in vitro assays.
Journal: Environmental health perspectives 19961001
Title: Alterations in Ca2+ transport ATPase and P-glycoprotein expression can mediate resistance to thapsigargin.
Journal: The Journal of biological chemistry 19940318
Title: Expression of P-glycoprotein in relation to clinical manifestation, treatment and prognosis of adrenocortical cancer.
Journal: European journal of cancer (Oxford, England : 1990) 19930101
Title: Comparison of the adrenalytic activity of mitotane and a methylated homolog on normal adrenal cortex and adrenal cortical carcinoma.
Journal: Cancer chemotherapy and pharmacology 19930101
Title: Possible mechanism and treatment of o,p'DDD-induced hypercholesterolaemia.
Journal: The Quarterly journal of medicine 19920901
Title: Neuropsychologic and neurologic side effects of mitotane and reversibility of symptoms.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19920901
Title: Reversible mental deterioration and neurological disturbances with o,p'-DDD therapy.
Journal: Clinical neurology and neurosurgery 19920101
Title: Mitotane enhances cytotoxicity of chemotherapy in cell lines expressing a multidrug resistance gene (mdr-1/P-glycoprotein) which is also expressed by adrenocortical carcinomas.
Journal: The Journal of clinical endocrinology and metabolism 19910701
Title: [Idiopathic intracranial hypertension during treatment of Cushing's disease with mitotane].
Journal: Presse medicale (Paris, France : 1983) 19871212
Title: [Neurotoxicity of mitotane therapy of adrenocortical carcinoma (5 cases) and Cushing's syndrome (7 cases)].
Journal: Presse medicale (Paris, France : 1983) 19870523
Title: Primary hypogonadism associated with o,p' DDD (mitotane) therapy.
Journal: Journal of toxicology. Clinical toxicology 19870101
Title: Toxicity, ultrastructural effects, and metabolic studies with 1-(o-chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane(o,p'-DDD) and its methyl analog in the guinea pig and rat.
Journal: Toxicology and applied pharmacology 19870101
Title: [The effects of o,p'-DDD on human adrenal steroid synthesis].
Journal: Nihon Naibunpi Gakkai zasshi 19840720
Title: Mitotane use in inoperable adrenal cortical carcinoma.
Journal: JAMA 19730305
Title: Gentilin E, Tagliati F, Terzolo M, Mitotane reduces human and mouse ACTH-secreting pituitary cell viability and function. J Endocrinol. 2013 Jul 29;218(3):275-285.
Title: Lehmann TP, Wrzesiński T, Jagodziński PP. The effect of mitotane on viability, steroidogenesis and gene expression in NCI H295R adrenocortical cells. Mol Med Rep. 2013 Mar;7(3):893-900.
Title: Takeshita A, Igarashi-Migitaka J, Koibuchi N, Mitotane induces CYP3A4 expression via activation of the steroid and xenobiotic receptor. J Endocrinol. 2013 Feb 15;216(3):297-305.
Title: Ederhy S, Cohen A, Dufaitre G, No evidence for relevant QT interval prolongation in mitotane-treated patients with adrenocortical carcinoma. J Endocrinol Invest. 2012 Nov;35(10):911-4.
Title: Alexandraki KI, Kaltsas GA, le Roux CW, Assessment of serum-free cortisol levels in patients with adrenocortical carcinoma treated with mitotane: a pilot study. Clin Endocrinol (Oxf). 2010 Mar;72(3):305-11.
