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41294-56-8,MFCD00868328
Catalog No.:AA00ILMD

41294-56-8 | Alfacalcidol

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ILMD
Chemical Name:
Alfacalcidol
CAS Number:
41294-56-8
Molecular Formula:
C27H44O2
Molecular Weight:
400.6371
MDL Number:
MFCD00868328
SMILES:
CC(CCCC(C1CCC2[C@]1(C)CCCC2=CC=C1CC(O)C[C@@H](C1=C)O)C)C
Properties
Properties
 
Form:
Solid  
MP:
134-136°C  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
643  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
2  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
6.8  

Downstream Synthesis Route
41294-56-8   
1α-hydroxy-6,19-dihydro-6,19-epidioxyvitaminD3 

[1]Yamada;Yamamoto;Naito;Suzuki;Ohmori;Takayama;Shiina;Miyaura;Tanaka;Abe[JournalofMedicinalChemistry,1985,vol.28,#9,p.1148-1153]

[1]Vanmaele;DeClercq;Vandewalle[TetrahedronLetters,1982,vol.23,#9,p.995-998]

[2]Lithgoe,Basil;Waterhouse,Ian[JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1405-1406]

[3]Igarashi,Jun-Etsu;Ikeda,Masahiko;Sunagawa,Makoto[BioorganicandMedicinalChemistryLetters,1996,vol.6,#13,p.1431-1436]

[1]Kawase,Akira;Ichikawa,Fumihiko;Koike,Nobuo;Kamachi,Shinichi;Stumpf,WalterE.;Nishii,Yasuho;Kubodera,Noboru[ChemicalandPharmaceuticalBulletin,2000,vol.48,#2,p.215-219]

[2]Calverley[TetrahedronLetters,1987,vol.28,#12,p.1337-1340]

[3]Kocienski,PhilipJ.;Lythgoe,Basil[JournaloftheChemicalSociety.PerkintransactionsI,1980,p.1400-1404]

[1]Trost,BarryM.;Dumas,Jacques;Villa,Marco[JournaloftheAmericanChemicalSociety,1992,vol.114,#25,p.9836-9845]

[2]Trost;Dumas[JournaloftheAmericanChemicalSociety,1992,vol.114,#5,p.1924-1925]

[1]Nemoto,Hideo;Kimura,Toshihiko;Kurobe,Hiroshi;Fukumoto,Keiichiro;Kametani,Tetsuji[JournaloftheChemicalSociety.PerkintransactionsI,1986,p.1777-1780]

[2]Nemoto,Hideo;Kimura,Toshihiko;Kurobe,Hiroshi;Fukumoto,Keiichiro;Kametani,Tetsuji[ChemistryLetters,1985,p.1131-1132]

Literature

Title: Vitamin D receptor agonist supplementation and suppression of inflammation may have advantage for all-cause mortality in hemodialysis patients.

Journal: Clinical and experimental nephrology 20121001

Title: Effect of alfacalcidol on cardiac function in patients with chronic kidney disease stage 4 and secondary hyperparathyroidism: a pilot study.

Journal: Scandinavian journal of urology and nephrology 20121001

Title: Bone effects of vitamin D - Discrepancies between in vivo and in vitro studies.

Journal: Archives of biochemistry and biophysics 20120701

Title: Changes in fibroblast growth factor 23 during treatment of secondary hyperparathyroidism with alfacalcidol or paricalcitol.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601

Title: Effect of alfacalcidol therapy on the survival of chronic hemodialysis patients.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20120601

Title: Long-term outcomes of children and adolescents who had cerebral palsy with secondary osteoporosis.

Journal: Current medical research and opinion 20120501

Title: Alfacalcidol-supplemented raloxifene therapy has greater bone-sparing effect than raloxifene-alone therapy in postmenopausal Japanese women with osteoporosis or osteopenia.

Journal: Journal of bone and mineral metabolism 20120501

Title: Green tea polyphenols and 1-α-OH-vitamin D₃ attenuate chronic inflammation-induced myocardial fibrosis in female rats.

Journal: Journal of medicinal food 20120301

Title: A randomised clinical study of alfacalcidol and paricalcitol.

Journal: Danish medical journal 20120201

Title: Alfacalcidol improves muscle power, muscle function and balance in elderly patients with reduced bone mass.

Journal: Rheumatology international 20120101

Title: Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20120101

Title: Effect of vitamin-D analogue on albuminuria in patients with non-dialysed chronic kidney disease stage 4-5: a retrospective single center study.

Journal: BMC nephrology 20120101

Title: Preoperative localization of intracranial lesions with MRI using marking pills.

Journal: Clinical neurology and neurosurgery 20111201

Title: Severe postpartum osteoporosis with increased PTHrP during lactation in a patient after total thyroidectomy and parathyroidectomy.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20111101

Title: Effects of alfacalcidol on circulating cytokines and growth factors in rat skeletal muscle.

Journal: The journal of physiological sciences : JPS 20111101

Title: No difference between alfacalcidol and paricalcitol in the treatment of secondary hyperparathyroidism in hemodialysis patients: a randomized crossover trial.

Journal: Kidney international 20111001

Title: New clinical trials with vitamin D and analogs in renal disease.

Journal: Kidney international 20111001

Title: Changes in macrophage inhibitory factor correlate with changes in bone mineral density in glucocorticoid-treated patients with rheumatoid arthritis.

Journal: Rheumatology (Oxford, England) 20111001

Title: Recommended dose of alfacacidol for osteoporosis.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20111001

Title: Elusive cause of hypomagnesaemia.

Journal: BMJ (Clinical research ed.) 20110930

Title: Vitamin D supplementation for prevention of mortality in adults.

Journal: The Cochrane database of systematic reviews 20110706

Title: A comparison of the effects of alendronate and alfacalcidol on bone mineral density around the femoral implant and in the lumbar spine after total hip arthroplasty.

Journal: The Journal of bone and joint surgery. American volume 20110706

Title: Protective actions of green tea polyphenols and alfacalcidol on bone microstructure in female rats with chronic inflammation.

Journal: The Journal of nutritional biochemistry 20110701

Title: Effects of alendronate plus alfacalcidol in osteoporosis patients with a high risk of fracture: the Japanese Osteoporosis Intervention Trial (JOINT) - 02.

Journal: Current medical research and opinion 20110601

Title: Guideline-practice gap in the management of predialysis chronic kidney disease mineral bone disorder in Japan.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20110601

Title: Active vitamin D and acute respiratory infections in dialysis patients.

Journal: Clinical journal of the American Society of Nephrology : CJASN 20110601

Title: Hypocalcemia following treatment for hyperthyroidism.

Journal: Clinical chemistry 20110601

Title: Effects of alfacalcidol on mechanical properties and collagen cross-links of the femoral diaphysis in glucocorticoid-treated rats.

Journal: Calcified tissue international 20110401

Title: Randomized trial comparing pulse calcitriol and alfacalcidol for the treatment of secondary hyperparathyroidism in haemodialysis patients.

Journal: Nephrology (Carlton, Vic.) 20110301

Title: Additive impact of alfacalcidol on bone mineral density and bone strength in alendronate treated postmenopausal women with reduced bone mass.

Journal: Journal of musculoskeletal & neuronal interactions 20110301

Title: A case of polyglandular autoimmune syndrome type I with unusual presentation.

Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20110301

Title: Effects of alfacalcidol on the contractile properties of the gastrocnemius medialis muscle in adult and old rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201

Title: Design of a pragmatic approach to evaluate the effectiveness of concurrent treatment for the prevention of osteoporotic fractures: rationale, aims and organization of a Japanese Osteoporosis Intervention Trial (JOINT) initiated by the Research Group of Adequate Treatment of Osteoporosis (A-TOP).

Journal: Journal of bone and mineral metabolism 20110101

Title: An open-label trial comparing alendronate and alphacalcidol in reducing falls and hip fractures in disabled stroke patients.

Journal: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20110101

Title: Alfacalcidol treatment restores derailed immune-regulation in patients with undifferentiated connective tissue disease.

Journal: Autoimmunity reviews 20110101

Title: Impact of hypovitaminosis D and alfacalcidol therapy on survival of hemodialysis patients: results from the French ARNOS study.

Journal: Nephron. Clinical practice 20110101

Title: Risk reduction of falls and fractures, reduction of back pain and safety in elderly high risk patients receiving combined therapy with alfacalcidol and alendronate: a prospective study.

Journal: Arzneimittel-Forschung 20110101

Title: Intravenous alfacalcidol once weekly pulse therapy for secondary hyperparathyroidism in hemodialysis patients.

Journal: Renal failure 20110101

Title: Potency of a combined alfacalcidol-alendronate therapy to reduce the risk of falls and fractures in elderly patients with glucocorticoid-induced osteoporosis.

Journal: Arzneimittel-Forschung 20110101

Title: A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues.

Journal: BMC biotechnology 20110101

Title: The safety and efficacy of early-stage bi-weekly alendronate to improve bone mineral density and bone turnover in chinese post-menopausal women at risk of osteoporosis.

Journal: The Journal of international medical research 20110101

Title: Post-parathyroidectomy parathyroid hormone levels: the impact on patient survival - a single-centre study in a stage 5 chronic kidney disease population.

Journal: Nephron. Clinical practice 20110101

Title: Regression of vascular calcification in a patient treated with cinacalcet: a case report.

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101

Title: [Examination of effects of alfacalcidol vitamin D supplement and renal function on improvement in the physical fitness of pre-frail elderly persons attending a nursing care prevention class].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20110101

Title: [The assessment of cynacalcet (Mimpara) accompanied by alfacalcidol treatment efficacy in haemodialysis patients with different secondary hyperparathyroidism severity recognized by iPTH].

Journal: Wiadomosci lekarskie (Warsaw, Poland : 1960) 20110101

Title: [Osteoporosis. Improving bone and muscle performance].

Journal: MMW Fortschritte der Medizin 20101202

Title: Effects of a vitamin D analog, alfacalcidol, on bone and skeletal muscle in glucocorticoid-treated rats.

Journal: Biomedical research (Tokyo, Japan) 20101201

Title: Synergistic effects of green tea polyphenols and alphacalcidol on chronic inflammation-induced bone loss in female rats.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20101101

Title: Impaired regulatory T-cell homeostasis due to vitamin D deficiency in undifferentiated connective tissue disease.

Journal: Scandinavian journal of rheumatology 20101101

Title: Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer.

Journal: Structure (London, England : 1993) 20101013

Title: Effects of alfacalcidol on muscle strength, muscle fatigue, and bone mineral density in normal and ovariectomized rats.

Journal: Biomedical research (Tokyo, Japan) 20101001

Title: Multicenter phase II trial of vitamin K(2) monotherapy and vitamin K(2) plus 1alpha-hydroxyvitamin D(3) combination therapy for low-risk myelodysplastic syndromes.

Journal: Leukemia research 20100901

Title: Comparison of the effects of eldecalcitol and alfacalcidol on bone and calcium metabolism.

Journal: The Journal of steroid biochemistry and molecular biology 20100701

Title: Failure of alphacalcidol (1alpha-hydroxyvitamin D3) in treating nutritional rickets and the biochemical response to ergocalciferol.

Journal: The Journal of steroid biochemistry and molecular biology 20100701

Title: Effects of treatment with risedronate and alfacalcidol on progression of atherosclerosis in postmenopausal women with type 2 diabetes mellitus accompanied with osteoporosis.

Journal: The American journal of the medical sciences 20100601

Title: Comparison of effects of alfacalcidol and alendronate on mechanical properties and bone collagen cross-links of callus in the fracture repair rat model.

Journal: Bone 20100401

Title: [Treatment of secondary hyperparathyroidism resistant to conventional therapy and tertiary hyperparathyroidism with Cinacalcet: an efficiency strategy].

Journal: Nephrologie & therapeutique 20100401

Title: Assessment of adherence to treatment of postmenopausal osteoporosis with raloxifene and/or alfacalcidol in postmenopausal Japanese women.

Journal: Journal of bone and mineral metabolism 20100301

Title: Administration of alfacalcidol for patients with predialysis chronic kidney disease may reduce cardiovascular disease events.

Journal: Clinical and experimental nephrology 20100201

Title: Autosomal dominant hypocalcemia caused by an activating mutation of the calcium-sensing receptor gene: the first case report in Korea.

Journal: Journal of Korean medical science 20100201

Title: Low-dose alfacalcidol controls secondary hyperparathyroidism in predialysis chronic kidney disease.

Journal: Nephron. Clinical practice 20100101

Title: Relation of oral 1alpha-hydroxy vitamin D3 to the progression of aortic arch calcification in hemodialysis patients.

Journal: Heart and vessels 20100101

Title: Vitamin D for the treatment of chronic painful conditions in adults.

Journal: The Cochrane database of systematic reviews 20100101

Title: High incidence rate of vertebral fractures during chronic prednisone treatment, in spite of bisphosphonate or alfacalcidol use. Extension of the alendronate or alfacalcidol in glucocorticoid-induced osteoporosis-trial.

Journal: Clinical and experimental rheumatology 20100101

Title: The administration of an active vitamin D(3) analogue reduced the serum concentrations of 1-84 and truncated parathyroid hormone in pseudohypoparathyroidism type Ib patients.

Journal: Endocrine journal 20100101

Title: Cost Effectiveness of Paricalcitol versus a non-selective vitamin D receptor activator for secondary hyperparathyroidism in the UK: a chronic kidney disease markov model.

Journal: Clinical drug investigation 20100101

Title: Cinacalcet in hyperparathyroidism secondary to X-linked hypophosphatemic rickets: case report and brief literature review.

Journal: Hormones (Athens, Greece) 20100101

Title: Effect of a six-month therapy with alfacalcidol on muscle power and balance and the number of fallers and falls.

Journal: Arzneimittel-Forschung 20100101

Title: Risedronate therapy for the prevention of steroid-induced osteoporosis in patients with minimal-change nephrotic syndrome.

Journal: Internal medicine (Tokyo, Japan) 20100101

Title: Ibandronate increases cortical bone density in patients with systemic lupus erythematosus on long-term glucocorticoid.

Journal: Arthritis research & therapy 20100101

Title: Alopecia in vitamin D-dependent rickets type II responding to 1α-hydroxycholecalciferol.

Journal: Annals of tropical paediatrics 20100101

Title: Overcoming resistance to bisphosphonates through the administration of alfacalcidol: results of a 1-year, open follow-up study.

Journal: Rheumatology international 20091101

Title: D-hormone derivatives for the treatment of osteoporosis: from alfacalcidol to eldecalcitol.

Journal: Mini reviews in medicinal chemistry 20091001

Title: The impact of pharmacist intervention on the use of activated vitamin D in a tertiary referral hospital in Malaysia.

Journal: The International journal of pharmacy practice 20091001

Title: A new look at the most successful prodrugs for active vitamin D (D hormone): alfacalcidol and doxercalciferol.

Journal: Molecules (Basel, Switzerland) 20090929

Title: Role of vitamin D treatment in glucose metabolism in polycystic ovary syndrome.

Journal: Fertility and sterility 20090901

Title: Combination of alfacalcidol with calcium can improve quadriceps muscle strength in elderly ambulatory Thai women who have hypovitaminosis D: a randomized controlled trial.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090901

Title: Comparison of the effects of alendronate and alfacalcidol on hip bone mineral density and bone turnover in Japanese men having osteoporosis or osteopenia with clinical risk factors for fractures.

Journal: Yonsei medical journal 20090831

Title: Potential of alfacalcidol for reducing increased risk of falls and fractures.

Journal: Rheumatology international 20090801

Title: Alfacalcidol prevents aromatase inhibitor (Letrozole)-induced bone mineral loss in young growing female rats.

Journal: The Journal of endocrinology 20090801

Title: Protective effects of 1-alpha-hydroxyvitamin D3 on residual beta-cell function in patients with adult-onset latent autoimmune diabetes (LADA).

Journal: Diabetes/metabolism research and reviews 20090701

Title: Safety of bisphosphonates in women of child bearing age.

Journal: Alimentary pharmacology & therapeutics 20090601

Title: [Economics of medicament therapies for osteoporosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20090501

Title: Differential effects of growth hormone and alpha calcidol on trabecular and cortical bones in hypophysectomized rats.

Journal: Pediatric research 20090401

Title: Clinical trial: comparison of alendronate and alfacalcidol in glucocorticoid-associated osteoporosis in patients with ulcerative colitis.

Journal: Alimentary pharmacology & therapeutics 20090215

Title: [New development in bisphosphonate treatment. Fracture prevention by bisphosphonates].

Journal: Clinical calcium 20090101

Title: Effects of risedronate or alfacalcidol on bone mineral density, bone turnover, back pain, and fractures in Japanese men with primary osteoporosis: results of a two-year strict observational study.

Journal: Journal of bone and mineral metabolism 20090101

Title: Immunological and clinical effects of alphacalcidol in patients with psoriatic arthropathy: results of an open, follow-up pilot study.

Journal: Acta dermato-venereologica 20090101

Title: The combination therapy with alfacalcidol and risedronate improves the mechanical property in lumbar spine by affecting the material properties in an ovariectomized rat model of osteoporosis.

Journal: BMC musculoskeletal disorders 20090101

Title: Alfacalcidol increases cancellous bone in low turnover, fatty marrow sites in aged, orchidectomized rats.

Journal: Journal of musculoskeletal & neuronal interactions 20090101

Title: Treatment of secondary hyperparathyroidism in haemodialysis patients: a randomised clinical trial comparing paricalcitol and alfacalcidol.

Journal: BMC nephrology 20090101

Title: Effects of alendronate and alfacalcidol on the femoral bone mass and bone strength in orchidectomized rats.

Journal: The Chinese journal of physiology 20081231

Title: A case of X-linked hypophosphatemic rickets: complications and the therapeutic use of cinacalcet.

Journal: European journal of endocrinology 20081201

Title: Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3.

Journal: The Journal of steroid biochemistry and molecular biology 20081201

Title: [Fall prevention: differences between native vitamin D, alfacalcidol and D-hormone].

Journal: MMW Fortschritte der Medizin 20081120

Title: Daily oral 25-hydroxycholecalciferol supplementation for vitamin D deficiency in haemodialysis patients: effects on mineral metabolism and bone markers.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101

Title: Alendronate protects premenopausal women from bone loss and fracture associated with high-dose glucocorticoid therapy.

Journal: The Journal of rheumatology 20081101

Title: Vitamin D receptor ligand therapy in chronic kidney disease.

Journal: Clinical nephrology 20081001

Title: Effects of combined administration of alfacalcidol and risedronate on cancellous and cortical bone mass of the tibia in glucocorticoid-treated young rats.

Journal: The Chinese journal of physiology 20080630

Title: Secondary osteoporosis in long-term bedridden patients with cerebral palsy.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20080601

Title: Intravenous alfacalcidol once weekly suppresses parathyroid hormone in hemodialysis patients.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20080401

Title: Efficacy of combined treatment with raloxifene and alfacalcidol on bone density and biochemical markers of bone turnover in postmenopausal osteoporosis.

Journal: Endocrine journal 20080301

Title: [Assessment of bone quality. Effects of bisphosphonates, raloxifene, alfacalcidol, and menatetrenone on bone quality: collagen cross-links, mineralization, and microdamage].

Journal: Clinical calcium 20080301

Title: Alfacalcidol-stimulated focal bone formation on the cancellous surface and increased bone formation on the periosteal surface of the lumbar vertebrae of adult female rats.

Journal: Calcified tissue international 20080201

Title: Differential effects of D-hormone analogs and native vitamin D on the risk of falls: a comparative meta-analysis.

Journal: Calcified tissue international 20080201

Title: Beneficial effects of combined administration of alendronate and alfacalcidol on cancellous bone mass of the tibia in orchidectomized rats: a bone histomorphometry study.

Journal: Journal of nutritional science and vitaminology 20080201

Title: Comparative therapeutic effects of orally administered 1,25-dihydroxyvitamin D(3) and 1alpha-hydroxyvitamin D(3) on type-1 diabetes in non-obese diabetic mice fed a normal-calcaemic diet.

Journal: Clinical and experimental immunology 20080101

Title: Oral calcitriol versus oral alfacalcidol for the treatment of secondary hyperparathyroidism in patients receiving hemodialysis: a randomized, crossover trial.

Journal: The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20080101

Title: Efficacy of intravenous alfacalcidol in the treatment of secondary hyperparathyroidism in patients on hemodialysis.

Journal: Nephron. Clinical practice 20080101

Title: Treatment of renal transplant recipients with low bone mineral density: a randomized prospective trial of alendronate, alfacalcidol, and alendronate combined with alfacalcidol.

Journal: Transplantation proceedings 20080101

Title: [Rhabdomyolysis in a patient with postoperative hypothyroidism and hypoparathyroidism].

Journal: Nihon Jinzo Gakkai shi 20080101

Title: Effect of alendronate on glucocorticoid-induced osteoporosis in Japanese women with systemic autoimmune diseases: versus alfacalcidol.

Journal: Modern rheumatology 20080101

Title: Alfacalcidol treatment increases bone mass from anticatabolic and anabolic effects on cancellous and cortical bone in intact female rats.

Journal: Journal of bone and mineral metabolism 20080101

Title: Greater efficacy of alfacalcidol in the red than in the yellow marrow skeletal sites in adult female rats.

Journal: Journal of musculoskeletal & neuronal interactions 20080101

Title: [Severe hypercalcemia as a complication of intensive treatment for osteoporosis due to steroid therpay in 17-year-old girl with the nephrotic syndrome].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080101

Title: Systematic review of the benefits and harms of calcitriol and alfacalcidol for fractures and falls.

Journal: Journal of bone and mineral metabolism 20080101

Title: Improving the outcome of established therapies for osteoporosis by adding the active D-hormone analog alfacalcidol.

Journal: Rheumatology international 20071201

Title: Intermittent or daily administration of 1-alpha calcidol for nephrectomised infants on peritoneal dialysis?

Journal: Pediatric nephrology (Berlin, Germany) 20071101

Title: Chemopreventive effect of a vitamin D(3) analog, alfacalcidol, on colorectal carcinogenesis in mice with ulcerative colitis.

Journal: Anti-cancer drugs 20071101

Title: Comparative studies on effect of risedronate and alfacalcidol against glucocorticoid-induced osteoporosis in rheumatoid arthritic patients.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901

Title: [GNAS1 gene abnormality in pseudohypoparathyroidism I a].

Journal: Clinical calcium 20070801

Title: [Difference in the therapeutic response to active vitamin D3 between PTH-deficient hypoparathyroidism and pseudohypoparathyroidism].

Journal: Clinical calcium 20070801

Title: Effects of alfacalcidol on cancellous and cortical bone mass in rats treated with glucocorticoid: a bone histomorphometry study.

Journal: Journal of nutritional science and vitaminology 20070601

Title: Prevention of glucocorticoid induced osteoporosis with alendronate or alfacalcidol: relations of change in bone mineral density, bone markers, and calcium homeostasis.

Journal: The Journal of rheumatology 20070501

Title: [Differential diagnosis of hypercalcemia].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: [Progress in diagnosis and therapy: Calcium sensing receptor gene abnormality and hypoparathyroidism].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: [Progress in diagnosis and therapy: Hypocalcemia due to idiopathic hypoparathyroidism].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: [Progress in diagnosis and therapy: Hypocalcemia due to pseudohypoparathyroidism].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: [X-linked hypophosphatemic rickets].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: [Tumor-induced hypophosphatemic osteomalacia].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: [Vitamin D-dependent rickets type I, II].

Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

Title: Superiority of a combined treatment of Alendronate and Alfacalcidol compared to the combination of Alendronate and plain vitamin D or Alfacalcidol alone in established postmenopausal or male osteoporosis (AAC-Trial).

Journal: Rheumatology international 20070301

Title: [Prevention of glucocorticoid induced osteoporosis with alendronate or alfacalcidol].

Journal: Medizinische Monatsschrift fur Pharmazeuten 20070301

Title: Interaction between activated VD3 and Ca channel blockers in patients undergoing hemodialysis.

Journal: International journal of clinical pharmacology and therapeutics 20070301

Title: Hereditary vitamin D-resistant rickets in Greek children: genotype, phenotype, and long-term response to treatment.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20070301

Title: Differences of therapeutic effects on regional bone mineral density and markers of bone mineral metabolism between alendronate and alfacalcidol in Japanese osteoporotic women.

Journal: The journal of medical investigation : JMI 20070201

Title: A comparative study on several models of experimental renal calcium oxalate stones formation in rats.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070201

Title: Bone mineral density in children with chronic renal failure.

Journal: Pediatric nephrology (Berlin, Germany) 20070101

Title: Postural stabilizing effect of alfacalcidol and active absorbable algal calcium (AAA Ca) compared with calcium carbonate assessed by computerized posturography.

Journal: Journal of bone and mineral metabolism 20070101

Title: Clinical effect of bisphosphonate and vitamin D on osteoporosis: reappraisal of a multicenter double-blind clinical trial comparing etidronate and alfacalcidol.

Journal: Journal of bone and mineral metabolism 20070101

Title: [Prevalence and quality of control of calcium and phosphorus metabolism disorders among Lithuanian hemodialysis patients in 2004 and 2005].

Journal: Medicina (Kaunas, Lithuania) 20070101

Title: Combined therapies in osteoporosis: bisphosphonates and vitamin D-hormone analogs.

Journal: Journal of musculoskeletal & neuronal interactions 20070101

Title: Vitamin D receptor activator selectivity in the treatment of secondary hyperparathyroidism: understanding the differences among therapies.

Journal: Drugs 20070101

Title: Nonclassical aspects of differential vitamin D receptor activation: implications for survival in patients with chronic kidney disease.

Journal: Drugs 20070101

Title: Health-economic comparison of paricalcitol, calcitriol and alfacalcidol for the treatment of secondary hyperparathyroidism during haemodialysis.

Journal: Clinical drug investigation 20070101

Title: Effects of a combined alendronate and calcitriol agent (Maxmarvil) on bone metabolism in Korean postmenopausal women: a multicenter, double-blind, randomized, placebo-controlled study.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20061201

Title: Effect of risedronate on the cortical and cancellous bone mass and mechanical properties in ovariectomized rats: a comparison with the effects of alfacalcidol.

Journal: Journal of nutritional science and vitaminology 20061201

Title: Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis.

Journal: The New England journal of medicine 20061116

Title: Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis.

Journal: The New England journal of medicine 20061116

Title: [Randomized controlled trials for the prevention and treatment of glucocorticoid-induced osteoporosis].

Journal: Clinical calcium 20061101

Title: Occurrence of overt celiac disease in the elderly following total thyroidectomy.

Journal: Journal of endocrinological investigation 20061001

Title: Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis.

Journal: The New England journal of medicine 20060817

Title: Regression of skeletal manifestations of hyperparathyroidism with oral vitamin D.

Journal: The Journal of clinical endocrinology and metabolism 20060701

Title: Therapeutic effect of risedronate on cancellous and cortical bone in ovariectomized osteopenic rats: a comparison with the effects of alfacalcidol.

Journal: Experimental animals 20060701

Title: Comparative effects of alendronate and alfacalcidol on cancellous and cortical bone mass and bone mechanical properties in ovariectomized rats.

Journal: Experimental animals 20060701

Title: [Should bisphosphonate treatment be used for super-old patients with osteoporosis?].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20060701

Title: [Vitamin D-dependent rickets type I, II].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060628

Title: [X-linked hypophosphatemic rickets].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060628

Title: A randomized trial of intermittent versus continuous oral alfacalcidol treatment of hyperparathyroidism in end-stage renal disease.

Journal: Clinical nephrology 20060601

Title: Tenofovir-induced renal tubular dysfunction presenting with hypocalcaemia.

Journal: The Journal of infection 20060401

Title: Pattern of bone mineral density in patients with sporadic idiopathic hypoparathyroidism.

Journal: Clinical endocrinology 20060401

Title: The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301

Title: Superiority of alfacalcidol compared to vitamin D plus calcium in lumbar bone mineral density in postmenopausal osteoporosis.

Journal: Rheumatology international 20060301

Title: Calcium supplementation does not reproduce the pharmacological efficacy of alfacalcidol for the treatment of osteoporosis in rats.

Journal: Calcified tissue international 20060301

Title: [Vitamin D1alpha-hydroxylase deficiency as the cause of severe rickets in a 1-year-old-old boy].

Journal: Ugeskrift for laeger 20060213

Title: Comparative therapeutic effects of alendronate and alfacalcidol on cancellous and cortical bone mass and mechanical properties in ovariectomized osteopenic rats.

Journal: Journal of nutritional science and vitaminology 20060201

Title: Subcutaneous fat necrosis associated with severe hypocalcaemia in a neonate.

Journal: Journal of perinatology : official journal of the California Perinatal Association 20060101

Title: Randomized trial comparing low-dose hormone replacement therapy and HRT plus 1alpha-OH-vitamin D3 (alfacalcidol) for treatment of postmenopausal bone loss.

Journal: Journal of bone and mineral metabolism 20060101

Title: [A head-to-head comparative study for evaluation of effectiveness among drugs for osteoporosis].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20060101

Title: [A long-term comparative study of calcitriol versus alphacalcidol in patients with secondary hyperparathyroidism on hemodialysis].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101

Title: Effects of alfacalcidol alone or in combination with elcatonin on incidence of osteoporotic vertebral fractures in postmenopausal women with spondylosis.

Journal: Journal of bone and mineral metabolism 20060101

Title: Health-economic comparison of paricalcitol, calcitriol and alfacalcidol for the treatment of secondary hyperparathyroidism during haemodialysis.

Journal: Clinical drug investigation 20060101

Title: Multidisciplinary approach for prescriptive management of mineral and bone metabolism in chronic kidney disease: development of a dietetic led protocol.

Journal: Journal of renal care 20060101

Title: [Postmenopausal osteoporosis. Digital Rx radiogrammetry in the diagnosis and follow-up of treatment with alfacalcidol].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101

Title: [Effects of alfacalcidol therapy on serum cytokine levels in patients with multiple sclerosis].

Journal: Srpski arhiv za celokupno lekarstvo 20051201

Title: Ferrocene-based Diels-Alder derivatization for the determination of 1alpha-hydroxyvitamin D3 in rat plasma by high-performance liquid chromatography-electrospray tandem mass spectrometry.

Journal: Analytical biochemistry 20051101

Title: [Diagnostic and therapeutic difficultes in pityriasis rubra pilaris--case report].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20051101

Title: [Hypoparathyroidism].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20051001

Title: Phytase and 1alpha-hydroxycholecalciferol supplementation of broiler chickens during the starting and growing/finishing phases.

Journal: Poultry science 20051001

Title: Routine isotope-dilution liquid chromatography-tandem mass spectrometry assay for simultaneous measurement of the 25-hydroxy metabolites of vitamins D2 and D3.

Journal: Clinical chemistry 20050901

Title: Introduction. D-hormones alfacalcidol and calcitriol for prevention and treatment of glucocorticoid/inflammation-induced osteoporosis.

Journal: The Journal of rheumatology. Supplement 20050901

Title: The D-hormone analog alfacalcidol: the pioneer beyond the horizon of osteoporosis treatment.

Journal: The Journal of rheumatology. Supplement 20050901

Title: Importance of alfacalcidol in clinical conditions characterized by high rate of bone loss.

Journal: The Journal of rheumatology. Supplement 20050901

Title: Alfacalcidol versus plain vitamin D in inflammation induced bone loss.

Journal: The Journal of rheumatology. Supplement 20050901

Title: Alfacalcidol versus plain vitamin D in the treatment of glucocorticoid/inflammation-induced osteoporosis.

Journal: The Journal of rheumatology. Supplement 20050901

Title: Low creatinine clearance, glucocorticoid treatment, rheumatoid arthritis--different etiologies for low D-hormone syndrome and its associated increased risk for falls.

Journal: The Journal of rheumatology. Supplement 20050901

Title: [Suspected case of pseudohypoparathyroidism type II].

Journal: Clinical calcium 20050901

Title: [Effect of vitamin D on remaining kidney function after chronic kidney failure in preservation period patient].

Journal: Clinical calcium 20050901

Title: [Prevention of glucocorticoid-induced osteoporosis in patients with primary glomerulonephritis].

Journal: Zhonghua yi xue za zhi 20050817

Title: Effect of intermittent administration of 200 IU intranasal salmon calcitonin and low doses of 1alpha(OH) vitamin D3 on bone mineral density of the lumbar spine and hip region and biochemical bone markers in women with postmenopausal osteoporosis: a pilot study.

Journal: Clinical rheumatology 20050601

Title: Parathyroid hormone and growth in children with chronic renal failure.

Journal: Kidney international 20050601

Title: A prospective randomized study for prevention of postrenal transplantation bone loss.

Journal: Kidney international 20050501

Title: 1-alpha-calcidol modulates major human monocyte antigens and toll-like receptors TLR 2 and TLR4 in vitro.

Journal: European journal of medical research 20050420

Title: Reduced cardiovascular mortality in oral 1alpha-hydroxy vitamin D3 users in a haemodialysis population; do CRP and MMP markers of inflammation reflect this finding?

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050401

Title: D-hormone analog alfacalcidol: an update on its role in post-menopausal osteoporosis and rheumatoid arthritis management.

Journal: Aging clinical and experimental research 20050401

Title: Vitamin D analogs versus native vitamin D in preventing bone loss and osteoporosis-related fractures: a comparative meta-analysis.

Journal: Calcified tissue international 20050301

Title: [Is therapy with calcium and vitamin D adequate in glucocorticoid induced and inflammation related osteoporosis?].

Journal: Zeitschrift fur Rheumatologie 20050301

Title: [Letter query to Zeitschrift für Rheumatologie by Dr. med. Ilka Schwarze FA of Internal Medicine and Rheumatology Center of Internal Medicine--Leipzig University Clinic].

Journal: Zeitschrift fur Rheumatologie 20050301

Title: Treatment with alfacalcidol in elderly people significantly decreases the high risk of falls associated with a low creatinine clearance of <65 ml/min.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20050201

Title: Control of parathyroid function in patients with a short history of hemodialysis.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20050201

Title: Trochanteric hip fracture in an elderly patient with leprosy during osteoporosis treatment with risedronate and alfacalcidol.

Journal: Journal of bone and mineral metabolism 20050101

Title: Comparison between 1alpha(OH)D3 and 1,25(OH)2D3 on the suppression of plasma PTH levels in uremic patients, evaluated by the 'whole' and 'intact' PTH assays.

Journal: Nephron. Clinical practice 20050101

Title: Lymphocyte PC-1 activity in patients on maintenance haemodialysis treated with human erythropoietin and 1-alpha-D3.

Journal: Annals of clinical biochemistry 20050101

Title: Comparisons between oral pulse alfacalcidol therapy and daily therapy in maintenance hemodialysis patients with secondary hyperparathyroidism: a randomized, controlled, and multicenter study.

Journal: Renal failure 20050101

Title: [Changes of control of disorders of calcium and phosphorus metabolism in Lithuanian hemodialysis centers 1996-2003].

Journal: Medicina (Kaunas, Lithuania) 20050101

Title: Modulation of bone turnover by alfacalcidol and/or alendronate does not prevent glucocorticoid-induced osteoporosis in growing minipigs.

Journal: Journal of bone and mineral metabolism 20050101

Title: The therapeutic effects of alfacalcidol on bone strength, muscle metabolism and prevention of falls and fractures.

Journal: Journal of musculoskeletal & neuronal interactions 20050101

Title: [Administration of 1 alpha-OH vitamin D3 and calcium prevents bone mass loss in patients with advanced prostatic carcinoma after orchidectomy treated with complete androgenic blockade].

Journal: Endokrynologia Polska 20050101

Title: Hypophosphataemic osteomalacia due to de Toni-Debre-Fanconi syndrome in a 19-year old girl.

Journal: Hormones (Athens, Greece) 20050101

Title: A prospective randomized study for the treatment of bone loss with vitamin d during kidney transplantation in children and adolescents.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201

Title: An assessment of dose-uniformity of samples delivered from paediatric oral droppers.

Journal: Journal of clinical pharmacy and therapeutics 20041201

Title: [IOF World Congress on Osteoporosis 14th - 18th May 2004, Rio de Janeiro].

Journal: Zeitschrift fur Rheumatologie 20041201

Title: Hammers and nails: a report.

Journal: Palliative medicine 20041201

Title: Questions on the superiority of alfacalcidol over plain vitamin D in the treatment of glucocorticoid-induced osteoporosis.

Journal: Rheumatology international 20041101

Title: Long-term follow-up study on bone mineral density and fractures after simultaneous pancreas-kidney transplantation.

Journal: Kidney international 20041101

Title: Comparative efficacy of hormone replacement therapy, etidronate, calcitonin, alfacalcidol, and vitamin K in postmenopausal women with osteoporosis: The Yamaguchi Osteoporosis Prevention Study.

Journal: The American journal of medicine 20041015

Title: Clinical significance of alendronate in postmenopausal type 2 diabetes mellitus.

Journal: Diabetes & metabolism 20040901

Title: [Vitamin D therapy in predialysis renal failure].

Journal: Clinical calcium 20040901

Title: Treatment of osteopenia and osteoporosis in renal transplant children and adolescents.

Journal: Pediatric transplantation 20040801

Title: Lack of generalizable evidence of the superiority of alfacalcidol over plain vitamin D in the treatment of glucocorticoid-induced osteoporosis: comment on the article by Ringe et al.

Journal: Rheumatology international 20040701

Title: An open, randomized, controlled study of transdermal hormone replacement therapy on the rate of bone loss in primary biliary cirrhosis.

Journal: Journal of internal medicine 20040701

Title: Prevention and therapy of osteoporosis: the roles of plain vitamin D and alfacalcidol.

Journal: Rheumatology international 20040701

Title: Phytase, citric acid, and 1alpha-hydroxycholecalciferol improve phytate phosphorus utilization in chicks fed a corn-soybean meal diet.

Journal: Poultry science 20040701

Title: [The trend in the development of the active vitamin D3 and its analogues].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040501

Title: [K/DOQI clinical practice guidelines for management of renal osteodystrophy in predialysis patients].

Journal: Clinical calcium 20040501

Title: [Clinical practice guidelines for severe renal hyperparathyroidism].

Journal: Clinical calcium 20040501

Title: Efficacy of alphacalcidol and calcitriol in primary and corticosteroid-induced osteoporosis: a meta-analysis of their effects on bone mineral density and fracture rate.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20040401

Title: Effect of 18 months of treatment with alfacalcidol on bone in patients with mild to moderate chronic renal failure.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040401

Title: Alendronate treatment of established primary osteoporosis in men: 3-year results of a prospective, comparative, two-arm study.

Journal: Rheumatology international 20040301

Title: Superiority of alfacalcidol over plain vitamin D in the treatment of glucocorticoid-induced osteoporosis.

Journal: Rheumatology international 20040301

Title: Alfacalcidol prevents age-related bone loss and causes an atypical pattern of bone formation in aged male rats.

Journal: Journal of musculoskeletal & neuronal interactions 20040301

Title: Alfacalcidol reduces the number of fallers in a community-dwelling elderly population with a minimum calcium intake of more than 500 mg daily.

Journal: Journal of the American Geriatrics Society 20040201

Title: [Secondary osteoporosis due to systemic autoimmune diseases and rheumatic diseases].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040201

Title: Lower risk for cardiovascular mortality in oral 1alpha-hydroxy vitamin D3 users in a haemodialysis population.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040101

Title: Etidronate prevents high dose glucocorticoid induced bone loss in premenopausal individuals with systemic autoimmune diseases.

Journal: The Journal of rheumatology 20040101

Title: Calcimimetics versus vitamin D: what are their relative roles?

Journal: Blood purification 20040101

Title: Supplementation with Alfacalcidol increases protein intake and serum albumin concentration in patients undergoing hemodialysis with hpoalbumineamia.

Journal: Blood purification 20040101

Title: Alfacalcidol reduces accelerated bone turnover in elderly women with osteoporosis.

Journal: Journal of bone and mineral metabolism 20040101

Title: Preventing bone loss in renal transplant recipients with vitamin D.

Journal: Journal of the American Society of Nephrology : JASN 20031101

Title: 1alpha-hydroxycholecalciferol has little effect on phytate phosphorus utilization in laying hen diets.

Journal: Poultry science 20031101

Title: Intermittent intravenous ibandronate injections reduce vertebral fracture risk in corticosteroid-induced osteoporosis: results from a long-term comparative study.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20031001

Title: [Osteoporosis. Don't forget the men!].

Journal: MMW Fortschritte der Medizin 20030911

Title: Prevention of postmenopausal bone loss with exchange for short-term HRT for 1alpha-hydroxycholecalciferol.

Journal: Maturitas 20030630

Title: [When do men's bones become brittle. A cause can be found only in every second patient].

Journal: MMW Fortschritte der Medizin 20030612

Title: Three-monthly ibandronate bolus injection offers favourable tolerability and sustained efficacy advantage over two years in established corticosteroid-induced osteoporosis.

Journal: Rheumatology (Oxford, England) 20030601

Title: Comparison of calcium and alfacalcidol supplement in the prevention of osteopenia after kidney transplantation.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20030601

Title: [Osteoporosis in men].

Journal: Deutsche medizinische Wochenschrift (1946) 20030425

Title: Effects of chronic administration of zonisamide, an antiepileptic drug, on bone mineral density and their prevention with alfacalcidol in growing rats.

Journal: Journal of pharmacological sciences 20030401

Title: Sevelamer hydrochloride with or without alphacalcidol or higher dialysate calcium vs calcium carbonate in dialysis patients: an open-label, randomized study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030301

Title: A new active vitamin D analog, ED-71, causes increase in bone mass with preferential effects on bone in osteoporotic patients.

Journal: Journal of cellular biochemistry 20030201

Title: Rationale for active vitamin D and analogs in the treatment of osteoporosis.

Journal: Journal of cellular biochemistry 20030201

Title: Effects of treatment with etidronate and alfacalcidol for osteogenesis imperfecta type I: a case report.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101

Title: Alfacalcidol treatment in multiple sclerosis.

Journal: Clinical neuropharmacology 20030101

Title: Effects of cyclical etidronate with alfacalcidol on lumbar bone mineral density, bone resorption, and back pain in postmenopausal women with osteoporosis.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20030101

Title: [D-hormone reduces rate of falls. In osteoporosis consider more than bone density].

Journal: MMW Fortschritte der Medizin 20021205

Title: Cross-linked C-terminal telopeptide of type I collagen in serum before and after treatment with alfacalcidol and calcium carbonate in early and moderate chronic renal failure.

Journal: Nephron 20021001

Title: Comparison of incadronate and alfacalcidol on increased bone turnover caused by ovariectomy in rats.

Journal: European journal of pharmacology 20020802

Title: Use of vitamin D(4) analogs to investigate differences in hepatic and target cell metabolism of vitamins D(2) and D(3).

Journal: Biochimica et biophysica acta 20020711

Title: A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis.

Journal: Calcified tissue international 20020701

Title: Studies on the efficacy of cholecalciferol and derivatives for stimulating phytate utilization in broilers.

Journal: Poultry science 20020701

Title: Curative effect of combined treatment with alendronate and 1 alpha-hydroxyvitamin D3 on bone loss by ovariectomy in aged rats.

Journal: Japanese journal of pharmacology 20020701

Title: Gluten-induced enteropathy (coeliac disease) revealed by resistance to treatment with levothyroxine and alfacalcidol in a sixty-eight-year-old patient: a case report.

Journal: Thyroid : official journal of the American Thyroid Association 20020701

Title: Liquid chromatography--mass spectrometric method combined with derivatization for determination of 1 alpha-hydroxyvitamin D(3) in human plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605

Title: Pharmacokinetics of 1,25(OH)(2)D(3) and 1alpha(OH)D(3) in normal and uraemic men.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020501

Title: Quantitative evaluation of 1-alpha-hydroxycholecalciferol as a cholecalciferol substitute for broilers.

Journal: Poultry science 20020501

Title: Vitamin D hormone inhibits osteoclastogenesis in vivo by decreasing the pool of osteoclast precursors in bone marrow.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020401

Title: ED-71, a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis.

Journal: Bone 20020401

Title: Plasma bone-specific alkaline phosphatase changes in hemodialysis patients treated by alfacalcidol.

Journal: Clinical nephrology 20020401

Title: [Advancement of treatment for osteoporosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020301

Title: [Hepatic osteodystrophy].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020301

Title: Treatment of male osteoporosis: recent advances with alendronate.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20020301

Title: Kidney microsomal 25- and 1alpha-hydroxylase in vitamin D metabolism: catalytic properties, molecular cloning, cellular localization and expression during development.

Journal: Biochimica et biophysica acta 20020227

Title: [Effect of alfacalcidol on bone and calcium metabolism in elderly women].

Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20020101

Title: Treatment of glucocorticoid-induced osteoporosis with calcium, vitamin D and D-metabolites.

Journal: Frontiers of hormone research 20020101

Title: [Alphacalcidol in the treatment of osteopenic syndrome in patients with bronchial asthma].

Journal: Terapevticheskii arkhiv 20020101

Title: Alendronate and pharmacological doses of 1alpha OHD3 therapy in a patient with McCune-Albright syndrome and accompanying hypophosphatemia.

Journal: Journal of bone and mineral metabolism 20020101

Title: Effects of 5-year treatment with elcatonin and alfacalcidol on lumbar bone mineral density and the incidence of vertebral fractures in postmenopausal women with osteoporosis: a retrospective study.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20020101

Title: Alfacalcidol in the therapy of renal bone disease.

Journal: International journal of clinical pharmacology and therapeutics 20011201

Title: UVB-induced conversion of 7-dehydrocholesterol to 1alpha,25-dihydroxyvitamin D3 in an in vitro human skin equivalent model.

Journal: The Journal of investigative dermatology 20011101

Title: 1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate.

Journal: The Journal of investigative dermatology 20011101

Title: [Effect of combined treatment with vitamin K2 and 1 alpha-(OH)-vitamin D3 on bone loss in ovariectomized rats].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010901

Title: Rapid improvement of osteomalacia by treatment in a case with Sjögren's syndrome, rheumatoid arthritis and renal tubular acidosis type 1.

Journal: Internal medicine (Tokyo, Japan) 20010801

Title: Additive effect of alfacalcidol on bone mineral density of the lumbar spine in Taiwanese postmenopausal women treated with hormone replacement therapy and calcium supplementation: a randomized 2-year study.

Journal: Clinical endocrinology 20010801

Title: Phenytoin-induced bone loss and its prevention with alfacalcidol or calcitriol in growing rats.

Journal: Calcified tissue international 20010801

Title: 1alpha-hydroxyvitamin D2 is less toxic but not bone selective relative to 1alpha-hydroxyvitamin D3 in ovariectomized rats.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401

Title: Hypercalcemia and human nature.

Journal: Clinical nephrology 20010401

Title: [Changes in calcium metabolism after kidney transplantation].

Journal: Magyar sebeszet 20010401

Title: Complications with reformulated one-alpha vitamin D.

Journal: BMJ (Clinical research ed.) 20010331

Title: Inverse correlation between the changes of lumbar bone mineral density and serum undercarboxylated osteocalcin after vitamin K2 (menatetrenone) treatment in children treated with glucocorticoid and alfacalcidol.

Journal: Endocrine journal 20010201

Title: Effect of 1alpha-hydroxyvitamin D3 and egg-shell calcium on bone metabolism in ovariectomized osteoporotic model rats.

Journal: Journal of bone and mineral metabolism 20010101

Title: Oral administration of 1 alpha hydroxyvitamin D3 inhibits tumor growth and metastasis of a murine osteosarcoma model.

Journal: Anticancer research 20010101

Title: Redifferentiation therapy in brain tumors: long-lasting complete regression of glioblastomas and an anaplastic astrocytoma under long term 1-alpha-hydroxycholecalciferol.

Journal: Journal of neuro-oncology 20010101

Title: Effect of intermittent cyclical treatment with etidronate disodium (HEBP) and calcium plus alphacalcidol in postmenopausal osteoporosis.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20010101

Title: 1alpha-Hydroxyvitamin D3 suppresses trabecular bone resorption by inhibiting osteoclastogenic potential in bone marrow cells after ovariectomy in mice.

Journal: Journal of bone and mineral metabolism 20010101

Title: [Effects of alfacalcidol on mineral density of bone tissue in patients with rheumatoid arthritis].

Journal: Klinicheskaia meditsina 20010101

Title: Association of transforming growth factor beta1 genotype with therapeutic response to active vitamin D for postmenopausal osteoporosis.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20000301

Title: Effect of 1 alpha-hydroxyvitamin D3 on serum levels of thyroid hormones in hyperthyroid patients with untreated Graves' disease.

Journal: Metabolism: clinical and experimental 19971001

Title: Increase of renal 25-hydroxyvitamin D3-24-hydroxylase activity and its messenger ribonucleic acid level in 1 alpha-hydroxyvitamin D3-administered rats: possibility of the presence of two forms of 24-hydroxylase.

Journal: Journal of nutritional science and vitaminology 19930401

Title: [Vitamin D-resistant rickets type II: apropos of 2 cases].

Journal: Pediatrie 19920101

Title: Transformation of 25- and 1 alpha-hydroxyvitamin D3 to 1 alpha, 25-dihydroxyvitamin D3 by using Streptomyces sp. strains.

Journal: Applied and environmental microbiology 19911001

Title: Danazol-induced hypercalcaemia in alphacalcidol-treated hypoparathyroidism.

Journal: Postgraduate medical journal 19891101

Title: [Long-term effect of 1 alpha-hydroxyvitamin D, calcium and thiazide administration on glucocorticoid-induced osteoporosis].

Journal: Nihon Naibunpi Gakkai zasshi 19890620

Title: Possible role for vitamin D in controlling breast cancer cell proliferation.

Journal: Lancet (London, England) 19890128

Title: 1 alpha-hydroxyvitamin D3 treatment of three patients with 1,25-dihydroxyvitamin D-receptor-defect rickets and alopecia.

Journal: Pediatrics 19870701

Title: Aspirin inhibition of 1 alpha-hydroxyvitamin D3 or parathyroid hormone induced hypercalcemia in vivo in rats. A mechanism independent of prostaglandin biosynthesis inhibition.

Journal: Biochemical pharmacology 19850601

Title: Galeşanu C, et al. [Postmenopausal osteoporosis. Digital Rx radiogrammetry in the diagnosis and follow-up of treatment with alfacalcidol Rev Med Chir Soc Med Nat Iasi. 2006 Oct-Dec;110(4):833-41.

Title: Nuijten M, et al. Cost Effectiveness of Paricalcitol versus a Non-Selective Vitamin D Receptor Activator for Secondary Hyperparathyroidism in the UK. Clin Drug Investig. 2010;30(8):545-57.

Title: Shiraishi A, et al. The advantage of alfacalcidol over vitamin D in the treatment of osteoporosis. Calcif Tissue Int. 1999 Oct;65(4):311-6.

Title: Nagaoka H, et al. Alfacalcidol enhances collagen quality in ovariectomized rat bones. J Orthop Res. 2014 Aug;32(8):1030-6.

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Tags:41294-56-8 Molecular Formula|41294-56-8 MDL|41294-56-8 SMILES|41294-56-8 Alfacalcidol