Name: Name:Isoprinosine
Brand: AABLOCKS
SKU: AA00IMFG
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00IMFG

Chemical Name: Isoprinosine

CAS Number: 36703-88-5

Molecular Formula: C52H78N10O17

Molecular Weight: 1115.2325

MDL Number: MFCD05662374

SMILES: CC(=O)Nc1ccc(cc1)C(=O)O.CC(=O)Nc1ccc(cc1)C(=O)O.CC(=O)Nc1ccc(cc1)C(=O)O.CC(CN(C)C)O.CC(CN(C)C)O.CC(CN(C)C)O.OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1[nH]cnc2=O

Properties

BP: 732.8°C at 760 mmHg

Form: Solid

MP: 140-142°C

Storage: Inert atmosphere;Room Temperature;

Complexity: 658

Covalently-Bonded Unit Count: 7

Defined Atom Stereocenter Count: 4

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 79

Hydrogen Bond Acceptor Count: 22

Hydrogen Bond Donor Count: 13

Isotope Atom Count: 0

Rotatable Bond Count: 14

Undefined Atom Stereocenter Count: 3

Undefined Bond Stereocenter Count: 0

Literature fold

Title: Effect of isoprinosine on rotavirus replication in vitro.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas19960201

Title: Inhibition of Pneumocystis carinii dihydropteroate synthetase by para-acetamidobenzoic acid: possible mechanism of action of isoprinosine in human immunodeficiency virus infection.

Journal: Antimicrobial agents and chemotherapy19930601

Title: Activities of antifolate, antiviral, and other drugs in an immunosuppressed rat model of Pneumocystis carinii pneumonia.

Journal: Antimicrobial agents and chemotherapy19920901

Title: Treatment of experimental pneumocystosis: review of 7 years of experience and development of a new system for classifying antimicrobial drugs.

Journal: Antimicrobial agents and chemotherapy19920901

Title: No effect of isoprinosine on HIV infection in vitro.

Journal: AIDS (London, England)19901001

Title: Inhibitory effect of selected antiviral compounds on measles (SSPE) virus replication in vitro.

Journal: Antiviral research19890901

Title: Influence of methisoprinol (isoprinosine) on HIV-infected human lymphocytes: in vitro immunological, virological, and ultrastructural studies.

Journal: Journal of clinical laboratory analysis19890101

Title: Isoprinosine-induced modulation of T-helper-cell subsets and antigen-presenting monocytes (Leu M3 + Ia +) resulted in improvement of T- and B-lymphocyte functions, in vitro in ARC and AIDS patients.

Journal: Clinical immunology and immunopathology19871101

Title: In-vitro inhibition of LAV/HTLV-III infected lymphocytes by dithiocarb and inosine pranobex.

Journal: Lancet (London, England)19851201

Title: Effect of isoprinosine against influenza and some other viruses causing respiratory diseases.

Journal: Antimicrobial agents and chemotherapy19720901

Title: Renoux G, et al. Isoprinosine as an immunopotentiator. J Immunopharmacol. 1979;1(3):337-56.

36703-88-5 | Isoprinosine