2921-57-5,MFCD00271782
Catalog No.:AA00JNVR

2921-57-5 | Methylprednisolone hydrogen hemisuccinate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$36.00   $25.00
- +
25mg
≥98%
in stock  
$82.00   $57.00
- +
50mg
≥98%
in stock  
$153.00   $107.00
- +
100mg
98%
in stock  
$250.00   $175.00
- +
500mg
98%
in stock  
$927.00   $649.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00JNVR
Chemical Name:
Methylprednisolone hydrogen hemisuccinate
CAS Number:
2921-57-5
Molecular Formula:
C26H34O8
Molecular Weight:
474.5434
MDL Number:
MFCD00271782
SMILES:
OC(=O)CCC(=O)OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)C
Properties
Properties
 
BP:
689.6°C at 760 mmHg  
Form:
Solid  
MP:
>230°C (dec.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
981  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  
XLogP3:
2.2  

Literature

Title: Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone.

Journal: BMC neuroscience 20130101

Title: Efficacy of intraoperative, single-bolus corticosteroid administration to prevent postoperative acute respiratory failure after oesophageal cancer surgery.

Journal: Interactive cardiovascular and thoracic surgery 20121001

Title: Ex vivo models to evaluate the role of ocular melanin in trans-scleral drug delivery.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815

Title: Dapsone hypersensitivity syndrome complicated by Scedosporium apiospermum pneumonia in an immunocompetent patient.

Journal: Infection 20120801

Title: Role of corticosteroid as a prophylactic measure in fat embolism syndrome: a literature review.

Journal: Musculoskeletal surgery 20120601

Title: Improvement of central visual function following steroid pulse therapy in acute zonal occult outer retinopathy.

Journal: Documenta ophthalmologica. Advances in ophthalmology 20120601

Title: Stability of extemporaneously prepared cytarabine, methotrexate sodium, and methylprednisolone sodium succinate.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120201

Title: Angioedema in a 47-year-old woman with hypocomplementemic urticarial vasculitis syndrome.

Journal: The Journal of the American Osteopathic Association 20120201

Title: Influence of treatment with intranasal corticosteroids on the nasal mucosa, weight, and corticosteroid concentration in rats.

Journal: American journal of rhinology & allergy 20120101

Title: Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats.

Journal: Turkish neurosurgery 20120101

Title: Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy.

Journal: Archives of dermatology 20111001

Title: Acute liver failure and aplastic anemia in an 11-year-old girl.

Journal: Digestive diseases and sciences 20110801

Title: Do corticosteroids affect lumbar spinal fusion? A rabbit model using high-dose methylprednisolone.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20110701

Title: Effects of systemic administration of methylprednisolone on residual hearing in an animal model of cochlear implantation.

Journal: Acta oto-laryngologica 20110601

Title: [The issue of methylprednisolone sodium succinate dosage for use].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics 20110501

Title: Intramedullary PNET of the spine: long-term survival after combined modality therapy and subsequent relapse.

Journal: Journal of pediatric hematology/oncology 20110301

Title: Lack of protective effect of local administration of triamcinolone or systemic treatment with methylprednisolone against damages caused by optic nerve crush in rats.

Journal: Experimental eye research 20110201

Title: No effect of steroids on seroma formation after mastectomy.

Journal: Danish medical bulletin 20110201

Title: An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate.

Journal: Biomaterials 20110101

Title: Immediate-type hypersensitivity to succinylated corticosteroids.

Journal: International archives of allergy and immunology 20110101

Title: Epstein Barr Virus-positive large T-cell lymphoma presenting as acute appendicitis 17 years after cadaveric renal transplant: a case report.

Journal: Journal of medical case reports 20110101

Title: Recurrent high-dose intravenous methylprednisolone succinate pulse therapy-induced hepatopathy in a patient with multiple sclerosis.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20110101

Title: Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids.

Journal: PloS one 20110101

Title: Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20101201

Title: [Pneumatosis cystoides intestinalis in a patient with lung cancer].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20101201

Title: [Clinical effect of methylprednisolone sodium succinate and mouse nerve growth factor for injection in treating acute spinal cord injury and cauda equina injury].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20101001

Title: Evaluation of the function of polymorphonuclear neutrophilic leukocytes in healthy dogs given a high dose of methylprednisolone sodium succinate.

Journal: American journal of veterinary research 20100501

Title: Photoreceptor changes in acute and resolved acute posterior multifocal placoid pigment epitheliopathy documented by spectral-domain optical coherence tomography.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20100501

Title: [Gemcitabine combined with cisplatin and methylprednisolone sodium succinate in chemotherapy for relapsed or refractory T cell non-Hodgkin lymphoma].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20100401

Title: Accidental epidural injection of thiopental in a dog.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20100301

Title: Idiopathic orbital inflammation and Graves ophthalmopathy.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20100101

Title: Retinal vasculitis associated with the anti-synthetase syndrome.

Journal: Ocular immunology and inflammation 20100101

Title: [A case of refractory pulmonary peripheral T cell lymphoma successfully treated with Cisplatin Plus Gemcitabine Plus Solumedrol].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20100101

Title: The Pott's puffy tumor: an unusual complication of frontal sinusitis, methods for its detection.

Journal: Pediatric dermatology 20100101

Title: [A case of Churg-Strauss syndrome with methylprednisolone sodium succinate allergy].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20091201

Title: Acute graft-versus-host-disease in kidney transplantation: case report and review of literature.

Journal: Transplantation proceedings 20091101

Title: [Preliminary experience with partial tolerance protocol in small bowel transplantation].

Journal: Zhonghua yi xue za zhi 20091020

Title: Does high dose methylprednisolone sodium succinate really improve neurological status in patient with acute cervical cord injury?: a prospective study about neurological recovery and early complications.

Journal: Spine 20090915

Title: Gastric mucosal injury in systemic lupus erythematosus patients receiving pulse methylprednisolone therapy.

Journal: British journal of clinical pharmacology 20090801

Title: Intra-arterial injection in the rat brain: evaluation of steroids used for transforaminal epidurals.

Journal: Spine 20090715

Title: Caution: all 'medrols' are not the same.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20090701

Title: Relationship of hormonal resuscitation therapy and central venous pressure on increasing organs for transplant.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090501

Title: Severe hypersensitivity reactions to corticosteroids in children.

Journal: Pediatric emergency care 20090501

Title: Acute allergic reaction due to milk proteins contaminating lactose added to corticosteroid for injection.

Journal: Allergology international : official journal of the Japanese Society of Allergology 20090301

Title: An alternative approach to a renal transplant patient who experienced an immediate type systemic reaction due to methylprednisolone sodium succinate.

Journal: Journal of investigational allergology & clinical immunology 20090101

Title: Quality of life assessment in patients with Graves' disease and progressive infiltrative ophthalmopathy during combined treatment with methylprednisolone and orbital radiotherapy.

Journal: Endokrynologia Polska 20090101

Title: Severe immunoglobulin E-mediated anaphylaxis to intravenous methylprednisolone succinate in a patient who tolerated oral methylprednisolone.

Journal: Journal of investigational allergology & clinical immunology 20090101

Title: The operation was a success, but the patient cannot see.

Journal: Survey of ophthalmology 20090101

Title: Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates.

Journal: Journal of pharmaceutical sciences 20080701

Title: Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor.

Journal: American journal of physiology. Endocrinology and metabolism 20080601

Title: An elderly patient with Bickerstaff brainstem encephalitis and transient episodes of brainstem dysfunction.

Journal: Archives of neurology 20080601

Title: [Purtscher-like retinopathy: case report and review of the literature].

Journal: Journal francais d'ophtalmologie 20080601

Title: Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats.

Journal: Pharmaceutical research 20080401

Title: Usefulness of oral macrogol challenge in anaphylaxis after intra-articular injection of corticosteroid preparation.

Journal: Allergy 20080401

Title: Vecuronium bromide and methylprednisolone succinate are physically incompatible!

Journal: Journal of neurosurgical anesthesiology 20080401

Title: In vitro evaluation of the effect of trans-10, cis-12 conjugated linoleic acid on phagocytosis by canine peripheral blood polymorphonuclear neutrophilic leukocytes exposed to methylprednisolone sodium succinate.

Journal: American journal of veterinary research 20080401

Title: Multiple sclerosis onset during etanercept treatment.

Journal: European neurology 20080101

Title: Characterization of a new experimental model of osteoporosis in rabbits.

Journal: Journal of bone and mineral metabolism 20080101

Title: Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.

Journal: BMC pulmonary medicine 20080101

Title: IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

Journal: PloS one 20080101

Title: Anaphylaxis due to methylprednisolone.

Journal: Journal of investigational allergology & clinical immunology 20080101

Title: Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d-galactosamine.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20071201

Title: Continuous infusion of methylprednisolone via paediatric parenteral nutrition: a pharmacokinetic animal study.

Journal: Clinical nutrition (Edinburgh, Scotland) 20070801

Title: Effects of alfacalcidol on cancellous and cortical bone mass in rats treated with glucocorticoid: a bone histomorphometry study.

Journal: Journal of nutritional science and vitaminology 20070601

Title: Rituximab plus ASHAP for the treatment of patients with relapsed or refractory aggressive non-Hodgkin's lymphoma: a single-centre study of 20 patients.

Journal: Annals of hematology 20070401

Title: Controlling liposomal drug release with low frequency ultrasound: mechanism and feasibility.

Journal: Langmuir : the ACS journal of surfaces and colloids 20070327

Title: Ciliochoroidal effusion syndrome associated with posterior scleritis.

Journal: Japanese journal of ophthalmology 20070101

Title: [A case of PAN with positive Hbs Ag cured by immunosuppressive and antiviral therapies: a case report].

Journal: Le Journal medical libanais. The Lebanese medical journal 20070101

Title: Preoperative high-dose steroid administration attenuates the surgical stress response following liver resection: results of a prospective randomized study.

Journal: Journal of hepato-biliary-pancreatic surgery 20070101

Title: Effects of the Second National Acute Spinal Cord Injury Study of high-dose methylprednisolone therapy on acute cervical spinal cord injury-results in spinal injuries center.

Journal: Spine 20061215

Title: Mn (III) tetrakis (4-benzoic acid) porphyrin administered into the intrathecal space reduces oxidative damage and neuron death after spinal cord injury: a comparison with methylprednisolone.

Journal: Journal of neurotrauma 20061201

Title: High dose glucocorticoid hampers bone formation and resorption after bone marrow ablation in rat.

Journal: Microscopy research and technique 20061001

Title: Successful desensitization to antithymocyte globulin in a child with aplastic anemia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060901

Title: Diffuse alveolar hemorrhage: retrospective review of clinical outcome in allogeneic transplant recipients treated with aminocaproic acid.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060901

Title: Co-solubilization of poorly soluble drugs by micellization and complexation.

Journal: International journal of pharmaceutics 20060817

Title: Reversible impairment of auditory callosal pathway in 5-fluorouracil-induced leukoencephalopathy: parallel changes in function and imaging.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20060801

Title: Emergency department treatment of anaphylaxis: is epinephrine always indicated?

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701

Title: Shrinking lung syndrome as a presenting manifestation of systemic lupus erythematosus in a female Kuwaiti.

Journal: Clinical rheumatology 20060501

Title: Apoptosis-related gene bcl-2 in lung tissue after experimental traumatic brain injury in rats.

Journal: Heart, lung & circulation 20060401

Title: Slowly progressive vision loss in giant cell arteritis.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20060301

Title: Worsening of asthma with systemic corticosteroids. A case report and review of literature.

Journal: Journal of general internal medicine 20060201

Title: [A case of drug-induced interstitial pneumonitis after gemcitabine treatment for advanced pancreatic cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20060101

Title: [Intravenous high dose glucocorticoids in patients with ankylosing spondylitis].

Journal: Terapevticheskii arkhiv 20060101

Title: Beneficial effect of methylprednisolone on cardiac myocytes in a rat model of severe brain injury.

Journal: The Tohoku journal of experimental medicine 20051001

Title: I almost crossed over.

Journal: Texas medicine 20051001

Title: Comparisons of steroid, acyclovir, lipoprostoglandin E1 and steroid + acyclovir treatments in facial paralysis: a rat study.

Journal: International journal of pediatric otorhinolaryngology 20050901

Title: [Pulmonary artery aneurysms in Behcet syndrome].

Journal: Revue de pneumologie clinique 20050901

Title: Dexamethasone-induced methylprednisolone hemisuccinate hydrolase: its identification as a member of the rat carboxylesterase 2 family and its unique existence in plasma.

Journal: Biochemical pharmacology 20050415

Title: Intratympanic steroid perfusion for refractory sudden sensorineural hearing loss.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20050401

Title: Pulmonary sarcoidosis presenting with acute respiratory failure.

Journal: Southern medical journal 20050301

Title: Successful recovery from interstitial pneumonitis, induced by bicalutamide and leuprorelin acetate given as treatment for prostate cancer.

Journal: Hinyokika kiyo. Acta urologica Japonica 20050301

Title: Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats.

Journal: Surgical neurology 20050101

Title: [An auto-iatrogenic disease].

Journal: Therapeutische Umschau. Revue therapeutique 20041201

Title: Decrease in oral bioavailability of ciclosporin by intravenous pulse of methylprednisolone succinate in rats.

Journal: The Journal of pharmacy and pharmacology 20041001

Title: The bioavailability of IV methylprednisolone and oral prednisone in multiple sclerosis.

Journal: Neurology 20040928

Title: Effects of MPSS and a potent iNOS inhibitor on traumatic spinal cord injury.

Journal: Neuroreport 20040915

Title: Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury.

Journal: International journal of clinical pharmacology and therapeutics 20040901

Title: Methylprednisolone sodium succinate in pediatric parenteral nutrition: influence of vehicle injection.

Journal: Clinical nutrition (Edinburgh, Scotland) 20040801

Title: Acute bullous eruption with compartment syndrome due to intravenous infiltration.

Journal: Archives of dermatology 20040701

Title: [Mantle cell lymphoma markedly infiltrated into adrenal glands with adrenal insufficiency].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20040701

Title: Effects of duration of ischemia and donor pretreatment with methylprednisolone or its macromolecular prodrug on the disposition of indocyanine green in cold-preserved rat livers.

Journal: Pharmaceutical research 20040601

Title: Serum sickness-like reaction and bupropion.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry 20040501

Title: Clinical presentation, natural history, and treatment of crescentic proliferative IgA nephropathy.

Journal: Seminars in nephrology 20040501

Title: Acute traumatic spinal cord injury, 1993-2000A population-based assessment of methylprednisolone administration and hospitalization.

Journal: The Journal of trauma 20040501

Title: Comparison of methylprednisolone with dexamethasone in treatment of acute spinal injury in rats.

Journal: Indian journal of experimental biology 20040501

Title: Influence of intravenous methylprednisolone pulse treatment on the disposition of ciclosporin and hepatic CYP3A activity in rats.

Journal: The Journal of pharmacy and pharmacology 20040401

Title: Effects of corticosteroids on inflammatory response following cardiopulmonary bypass.

Journal: Croatian medical journal 20040401

Title: Central retinal artery occlusion as the initial ophthalmic presentation of Susac's syndrome.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20040401

Title: Anaphylaxis following administration of intravenous methylprednisolone sodium succinate in a renal transplant recipient.

Journal: International journal of urology : official journal of the Japanese Urological Association 20040301

Title: [Orbital extension of sinus plasmacytoma secondarily transforming into multiple myeloma: a case study].

Journal: Journal francais d'ophtalmologie 20040101

Title: Update on pharmaceutical trials in acute spinal cord injury.

Journal: The journal of spinal cord medicine 20040101

Title: Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.

Journal: Internal medicine (Tokyo, Japan) 20031201

Title: [Wegener's granulomatosis (morbus Wegener)].

Journal: Praxis 20031112

Title: Interstitial pneumonitis induced by bicalutamide and leuprorelin acetate for prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20031101

Title: What's wrong with this patient? POEMS syndrome.

Journal: RN 20031101

Title: Intraoperative solumedrol helps prevent postpneumonectomy pulmonary edema.

Journal: The Annals of thoracic surgery 20031001

Title: Decreased bone mineral density in the pediatric renal transplant population.

Journal: Pediatric transplantation 20031001

Title: Intravenous corticosteroids to reduce gemtuzumab ozogamicin infusion reactions.

Journal: The Annals of pharmacotherapy 20030901

Title: Salvage chemotherapy according to the ASHAP protocol: a single-center study of 24 patients with relapsed or refractory aggressive non-Hodgkin's lymphomas.

Journal: Annals of hematology 20030801

Title: Crescentic, proliferative IgA nephropathy: clinical and histological response to methylprednisolone and intravenous cyclophosphamide.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030701

Title: High- and low-risk profiles for the development of multiple sclerosis within 10 years after optic neuritis: experience of the optic neuritis treatment trial.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20030701

Title: Steroid-free immunosuppression during and after liver transplantation--a 3-yr follow-up report.

Journal: Clinical transplantation 20030601

Title: Hypersensitivity and idiosyncratic reactions to oxaliplatin.

Journal: Cancer 20030501

Title: Severe acute respiratory syndrome. The Mount Sinai experience.

Journal: The Canadian nurse 20030501

Title: An 89-year-old woman with angioedema during t-PA infusion for acute ischemic stroke.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20030401

Title: High-dose steroids, ursodeoxycholic acid, and chronic intravenous antibiotics improve bile flow after Kasai procedure in infants with biliary atresia.

Journal: Journal of pediatric surgery 20030301

Title: The 'crashing asthmatic.'.

Journal: American family physician 20030301

Title: [Graves' ophthalmopathy: diagnosis and highlights on etiopathogenesis and treatment].

Journal: La Tunisie medicale 20030301

Title: Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: local immunosuppressive effects in liver after systemic administration to rats.

Journal: Pharmaceutical research 20030201

Title: Acute posterior multifocal placoid pigment epitheliopathy associated with a systemic necrotizing vasculitis.

Journal: Retina (Philadelphia, Pa.) 20030201

Title: [Side effects during treatment with Solu-Medrol for optic neuritis in the course of MS].

Journal: Klinika oczna 20030101

Title: Degradation of methylprednisolone sodium succinate in a diluent-containing vial.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021215

Title: IgE-mediated anaphylactic reaction induced by succinate ester of methylprednisolone.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021001

Title: Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815

Title: Subtenon's depot corticosteroid injections in patients with a history of corticosteroid-induced intraocular pressure elevation.

Journal: American journal of ophthalmology 20020201

Title: Stevens-Johnson syndrome developing in a girl with systemic lupus erythematosus on high-dose corticosteroid therapy.

Journal: Pediatric dermatology 20020101

Title: Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels.

Journal: Experimental eye research 20020101

Title: Effect of steroids on lipopolysaccharide/interleukin 2-induced interleukin 18 production in peripheral blood mononuclear cells.

Journal: The Journal of international medical research 20020101

Title: Partial reversal of methylprednisolone-induced opacity in isolated rat lenses.

Journal: Ophthalmic research 20020101

Title: Steroids for acute spinal cord injury.

Journal: The Cochrane database of systematic reviews 20020101

Title: Stevens-Johnson syndrome: case presentation.

Journal: The Journal of clinical pediatric dentistry 20020101

Title: Stability of methylprednisolone sodium succinate in autodose infusion system bags.

Journal: Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20020101

Title: Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: plasma and tissue disposition.

Journal: Journal of pharmaceutical sciences 20011201

Title: Effect of short-course, high-dose steroid therapy in a child with myelodysplastic syndrome.

Journal: Pediatric hematology and oncology 20011201

Title: Systemic steroid pretreatment improves cerebral protection after circulatory arrest.

Journal: The Annals of thoracic surgery 20011101

Title: Preoperative administration of steroids: influence on adhesion molecules and cytokines after cardiopulmonary bypass.

Journal: The Annals of thoracic surgery 20011001

Title: The effects of glucocorticoid therapy on inflammatory responses to coronary artery bypass graft surgery.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20010901

Title: Radiation therapy after a partial response to CHOP chemotherapy for aggressive lymphomas.

Journal: International journal of radiation oncology, biology, physics 20010701

Title: Corticosteroids alter the differentiated phenotype of articular chondrocytes.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20010701

Title: Stability of methylprednisolone sodium succinate in pediatric parenteral nutrition mixtures.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010615

Title: Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone.

Journal: Journal of neurochemistry 20010501

Title: Effects of preoperative steroid administration on surgical stress in hepatic resection: prospective randomized trial.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20010301

Title: Methylprednisolone does not benefit patients undergoing coronary artery bypass grafting and early tracheal extubation.

Journal: The Journal of thoracic and cardiovascular surgery 20010301

Title: [Central serous chorioretinopathy and systemic steroid therapy].

Journal: Journal francais d'ophtalmologie 20010201

Title: Methylprednisolone concentrations in the vitreous and the serum after pulse therapy.

Journal: Retina (Philadelphia, Pa.) 20010101

Title: Induction strategy using basiliximab combined with mycophenolate MMF and immediate low-dose cyclosporin is steroid sparing and more effective than OKT3.

Journal: Transplantation proceedings 20010101

Title: Pulse methylprednisolone therapy for arthritis causing muscle weakness.

Journal: Annals of the rheumatic diseases 19990901

Title: Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine.

Journal: Clinical nephrology 19981001

Title: Steroid-pulse therapy in pemphigus vulgaris long term follow-up.

Journal: International journal of dermatology 19950601

Title: Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone.

Journal: Journal of neurology 19930501

Title: Systemic allergic reactions to corticosteroids.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma 19910101

Title: Fatal acute pyelonephritis following pulsed methylprednisolone for rheumatoid arthritis.

Journal: Annals of the rheumatic diseases 19901101

Title: Dapsone hepatitis.

Journal: Archives of internal medicine 19870101

Title: Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy.

Journal: Clinical and investigative medicine. Medecine clinique et experimentale 19861101

Title: An attempt to develop a model to study the effects of intrathecal steroids.

Journal: European journal of anaesthesiology 19860301

Title: Intractable hiccups associated with high-dose intravenous methylprednisolone therapy.

Journal: Annals of internal medicine 19860101

Title: Positive synergism between diuretics and methylprednisolone following acute myocardial infarction.

Journal: The Journal of international medical research 19860101

Title: Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6.

Title: Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000.

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Tags:2921-57-5 Molecular Formula|2921-57-5 MDL|2921-57-5 SMILES|2921-57-5 Methylprednisolone hydrogen hemisuccinate
Catalog No.: AA00JNVR
2921-57-5,MFCD00271782
2921-57-5 | Methylprednisolone hydrogen hemisuccinate
Pack Size: 10mg
Purity: ≥98%
in stock
$36.00 $25.00
Pack Size: 25mg
Purity: ≥98%
in stock
$82.00 $57.00
Pack Size: 50mg
Purity: ≥98%
in stock
$153.00 $107.00
Pack Size: 100mg
Purity: 98%
in stock
$250.00 $175.00
Pack Size: 500mg
Purity: 98%
in stock
$927.00 $649.00
Quantity
- +
Add to Card
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Technical Information
Catalog Number: AA00JNVR
Chemical Name: Methylprednisolone hydrogen hemisuccinate
CAS Number: 2921-57-5
Molecular Formula: C26H34O8
Molecular Weight: 474.5434
MDL Number: MFCD00271782
SMILES: OC(=O)CCC(=O)OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)C
Properties
BP: 689.6°C at 760 mmHg  
Form: Solid  
MP: >230°C (dec.)  
Storage: Keep in dry area;2-8℃;  
Complexity: 981  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 8  
Heavy Atom Count: 34  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 7  
XLogP3: 2.2  
Literature fold

Title: Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone.

Journal: BMC neuroscience20130101

Title: Efficacy of intraoperative, single-bolus corticosteroid administration to prevent postoperative acute respiratory failure after oesophageal cancer surgery.

Journal: Interactive cardiovascular and thoracic surgery20121001

Title: Ex vivo models to evaluate the role of ocular melanin in trans-scleral drug delivery.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20120815

Title: Dapsone hypersensitivity syndrome complicated by Scedosporium apiospermum pneumonia in an immunocompetent patient.

Journal: Infection20120801

Title: Role of corticosteroid as a prophylactic measure in fat embolism syndrome: a literature review.

Journal: Musculoskeletal surgery20120601

Title: Improvement of central visual function following steroid pulse therapy in acute zonal occult outer retinopathy.

Journal: Documenta ophthalmologica. Advances in ophthalmology20120601

Title: Stability of extemporaneously prepared cytarabine, methotrexate sodium, and methylprednisolone sodium succinate.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20120201

Title: Angioedema in a 47-year-old woman with hypocomplementemic urticarial vasculitis syndrome.

Journal: The Journal of the American Osteopathic Association20120201

Title: Influence of treatment with intranasal corticosteroids on the nasal mucosa, weight, and corticosteroid concentration in rats.

Journal: American journal of rhinology & allergy20120101

Title: Effect of curcumin on lipid peroxidation, early ultrastructural findings and neurological recovery after experimental spinal cord contusion injury in rats.

Journal: Turkish neurosurgery20120101

Title: Localized skin necrosis of steroid-induced striae distensae: an unusual complication of bevacizumab and irinotecan therapy.

Journal: Archives of dermatology20111001

Title: Acute liver failure and aplastic anemia in an 11-year-old girl.

Journal: Digestive diseases and sciences20110801

Title: Do corticosteroids affect lumbar spinal fusion? A rabbit model using high-dose methylprednisolone.

Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association20110701

Title: Effects of systemic administration of methylprednisolone on residual hearing in an animal model of cochlear implantation.

Journal: Acta oto-laryngologica20110601

Title: [The issue of methylprednisolone sodium succinate dosage for use].

Journal: Zhonghua er ke za zhi = Chinese journal of pediatrics20110501

Title: Intramedullary PNET of the spine: long-term survival after combined modality therapy and subsequent relapse.

Journal: Journal of pediatric hematology/oncology20110301

Title: Lack of protective effect of local administration of triamcinolone or systemic treatment with methylprednisolone against damages caused by optic nerve crush in rats.

Journal: Experimental eye research20110201

Title: No effect of steroids on seroma formation after mastectomy.

Journal: Danish medical bulletin20110201

Title: An injectable thiol-acrylate poly(ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate.

Journal: Biomaterials20110101

Title: Immediate-type hypersensitivity to succinylated corticosteroids.

Journal: International archives of allergy and immunology20110101

Title: Epstein Barr Virus-positive large T-cell lymphoma presenting as acute appendicitis 17 years after cadaveric renal transplant: a case report.

Journal: Journal of medical case reports20110101

Title: Recurrent high-dose intravenous methylprednisolone succinate pulse therapy-induced hepatopathy in a patient with multiple sclerosis.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre20110101

Title: Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids.

Journal: PloS one20110101

Title: Effect of granulocyte-colony stimulating factor on spinal cord tissue after experimental contusion injury.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia20101201

Title: [Pneumatosis cystoides intestinalis in a patient with lung cancer].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society20101201

Title: [Clinical effect of methylprednisolone sodium succinate and mouse nerve growth factor for injection in treating acute spinal cord injury and cauda equina injury].

Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery20101001

Title: Evaluation of the function of polymorphonuclear neutrophilic leukocytes in healthy dogs given a high dose of methylprednisolone sodium succinate.

Journal: American journal of veterinary research20100501

Title: Photoreceptor changes in acute and resolved acute posterior multifocal placoid pigment epitheliopathy documented by spectral-domain optical coherence tomography.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20100501

Title: [Gemcitabine combined with cisplatin and methylprednisolone sodium succinate in chemotherapy for relapsed or refractory T cell non-Hodgkin lymphoma].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20100401

Title: Accidental epidural injection of thiopental in a dog.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne20100301

Title: Idiopathic orbital inflammation and Graves ophthalmopathy.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20100101

Title: Retinal vasculitis associated with the anti-synthetase syndrome.

Journal: Ocular immunology and inflammation20100101

Title: [A case of refractory pulmonary peripheral T cell lymphoma successfully treated with Cisplatin Plus Gemcitabine Plus Solumedrol].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society20100101

Title: The Pott's puffy tumor: an unusual complication of frontal sinusitis, methods for its detection.

Journal: Pediatric dermatology20100101

Title: [A case of Churg-Strauss syndrome with methylprednisolone sodium succinate allergy].

Journal: Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society20091201

Title: Acute graft-versus-host-disease in kidney transplantation: case report and review of literature.

Journal: Transplantation proceedings20091101

Title: [Preliminary experience with partial tolerance protocol in small bowel transplantation].

Journal: Zhonghua yi xue za zhi20091020

Title: Does high dose methylprednisolone sodium succinate really improve neurological status in patient with acute cervical cord injury?: a prospective study about neurological recovery and early complications.

Journal: Spine20090915

Title: Gastric mucosal injury in systemic lupus erythematosus patients receiving pulse methylprednisolone therapy.

Journal: British journal of clinical pharmacology20090801

Title: Intra-arterial injection in the rat brain: evaluation of steroids used for transforaminal epidurals.

Journal: Spine20090715

Title: Caution: all 'medrols' are not the same.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association20090701

Title: Relationship of hormonal resuscitation therapy and central venous pressure on increasing organs for transplant.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation20090501

Title: Severe hypersensitivity reactions to corticosteroids in children.

Journal: Pediatric emergency care20090501

Title: Acute allergic reaction due to milk proteins contaminating lactose added to corticosteroid for injection.

Journal: Allergology international : official journal of the Japanese Society of Allergology20090301

Title: An alternative approach to a renal transplant patient who experienced an immediate type systemic reaction due to methylprednisolone sodium succinate.

Journal: Journal of investigational allergology & clinical immunology20090101

Title: Quality of life assessment in patients with Graves' disease and progressive infiltrative ophthalmopathy during combined treatment with methylprednisolone and orbital radiotherapy.

Journal: Endokrynologia Polska20090101

Title: Severe immunoglobulin E-mediated anaphylaxis to intravenous methylprednisolone succinate in a patient who tolerated oral methylprednisolone.

Journal: Journal of investigational allergology & clinical immunology20090101

Title: The operation was a success, but the patient cannot see.

Journal: Survey of ophthalmology20090101

Title: Synthesis and in vitro characterization of novel dextran-methylprednisolone conjugates with peptide linkers: effects of linker length on hydrolytic and enzymatic release of methylprednisolone and its peptidyl intermediates.

Journal: Journal of pharmaceutical sciences20080701

Title: Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor.

Journal: American journal of physiology. Endocrinology and metabolism20080601

Title: An elderly patient with Bickerstaff brainstem encephalitis and transient episodes of brainstem dysfunction.

Journal: Archives of neurology20080601

Title: [Purtscher-like retinopathy: case report and review of the literature].

Journal: Journal francais d'ophtalmologie20080601

Title: Modeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in rats.

Journal: Pharmaceutical research20080401

Title: Usefulness of oral macrogol challenge in anaphylaxis after intra-articular injection of corticosteroid preparation.

Journal: Allergy20080401

Title: Vecuronium bromide and methylprednisolone succinate are physically incompatible!

Journal: Journal of neurosurgical anesthesiology20080401

Title: In vitro evaluation of the effect of trans-10, cis-12 conjugated linoleic acid on phagocytosis by canine peripheral blood polymorphonuclear neutrophilic leukocytes exposed to methylprednisolone sodium succinate.

Journal: American journal of veterinary research20080401

Title: Multiple sclerosis onset during etanercept treatment.

Journal: European neurology20080101

Title: Characterization of a new experimental model of osteoporosis in rabbits.

Journal: Journal of bone and mineral metabolism20080101

Title: Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.

Journal: BMC pulmonary medicine20080101

Title: IRES-mediated translation of utrophin A is enhanced by glucocorticoid treatment in skeletal muscle cells.

Journal: PloS one20080101

Title: Anaphylaxis due to methylprednisolone.

Journal: Journal of investigational allergology & clinical immunology20080101

Title: Methylprednisolone injection via the portal vein suppresses inflammation in acute liver failure induced in rats by lipopolysaccharide and d-galactosamine.

Journal: Liver international : official journal of the International Association for the Study of the Liver20071201

Title: Continuous infusion of methylprednisolone via paediatric parenteral nutrition: a pharmacokinetic animal study.

Journal: Clinical nutrition (Edinburgh, Scotland)20070801

Title: Effects of alfacalcidol on cancellous and cortical bone mass in rats treated with glucocorticoid: a bone histomorphometry study.

Journal: Journal of nutritional science and vitaminology20070601

Title: Rituximab plus ASHAP for the treatment of patients with relapsed or refractory aggressive non-Hodgkin's lymphoma: a single-centre study of 20 patients.

Journal: Annals of hematology20070401

Title: Controlling liposomal drug release with low frequency ultrasound: mechanism and feasibility.

Journal: Langmuir : the ACS journal of surfaces and colloids20070327

Title: Ciliochoroidal effusion syndrome associated with posterior scleritis.

Journal: Japanese journal of ophthalmology20070101

Title: [A case of PAN with positive Hbs Ag cured by immunosuppressive and antiviral therapies: a case report].

Journal: Le Journal medical libanais. The Lebanese medical journal20070101

Title: Preoperative high-dose steroid administration attenuates the surgical stress response following liver resection: results of a prospective randomized study.

Journal: Journal of hepato-biliary-pancreatic surgery20070101

Title: Effects of the Second National Acute Spinal Cord Injury Study of high-dose methylprednisolone therapy on acute cervical spinal cord injury-results in spinal injuries center.

Journal: Spine20061215

Title: Mn (III) tetrakis (4-benzoic acid) porphyrin administered into the intrathecal space reduces oxidative damage and neuron death after spinal cord injury: a comparison with methylprednisolone.

Journal: Journal of neurotrauma20061201

Title: High dose glucocorticoid hampers bone formation and resorption after bone marrow ablation in rat.

Journal: Microscopy research and technique20061001

Title: Successful desensitization to antithymocyte globulin in a child with aplastic anemia.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20060901

Title: Diffuse alveolar hemorrhage: retrospective review of clinical outcome in allogeneic transplant recipients treated with aminocaproic acid.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation20060901

Title: Co-solubilization of poorly soluble drugs by micellization and complexation.

Journal: International journal of pharmaceutics20060817

Title: Reversible impairment of auditory callosal pathway in 5-fluorouracil-induced leukoencephalopathy: parallel changes in function and imaging.

Journal: Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology20060801

Title: Emergency department treatment of anaphylaxis: is epinephrine always indicated?

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20060701

Title: Shrinking lung syndrome as a presenting manifestation of systemic lupus erythematosus in a female Kuwaiti.

Journal: Clinical rheumatology20060501

Title: Apoptosis-related gene bcl-2 in lung tissue after experimental traumatic brain injury in rats.

Journal: Heart, lung & circulation20060401

Title: Slowly progressive vision loss in giant cell arteritis.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20060301

Title: Worsening of asthma with systemic corticosteroids. A case report and review of literature.

Journal: Journal of general internal medicine20060201

Title: [A case of drug-induced interstitial pneumonitis after gemcitabine treatment for advanced pancreatic cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy20060101

Title: [Intravenous high dose glucocorticoids in patients with ankylosing spondylitis].

Journal: Terapevticheskii arkhiv20060101

Title: Beneficial effect of methylprednisolone on cardiac myocytes in a rat model of severe brain injury.

Journal: The Tohoku journal of experimental medicine20051001

Title: I almost crossed over.

Journal: Texas medicine20051001

Title: Comparisons of steroid, acyclovir, lipoprostoglandin E1 and steroid + acyclovir treatments in facial paralysis: a rat study.

Journal: International journal of pediatric otorhinolaryngology20050901

Title: [Pulmonary artery aneurysms in Behcet syndrome].

Journal: Revue de pneumologie clinique20050901

Title: Dexamethasone-induced methylprednisolone hemisuccinate hydrolase: its identification as a member of the rat carboxylesterase 2 family and its unique existence in plasma.

Journal: Biochemical pharmacology20050415

Title: Intratympanic steroid perfusion for refractory sudden sensorineural hearing loss.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery20050401

Title: Pulmonary sarcoidosis presenting with acute respiratory failure.

Journal: Southern medical journal20050301

Title: Successful recovery from interstitial pneumonitis, induced by bicalutamide and leuprorelin acetate given as treatment for prostate cancer.

Journal: Hinyokika kiyo. Acta urologica Japonica20050301

Title: Magnesium sulfate treatment decreases caspase-3 activity after experimental spinal cord injury in rats.

Journal: Surgical neurology20050101

Title: [An auto-iatrogenic disease].

Journal: Therapeutische Umschau. Revue therapeutique20041201

Title: Decrease in oral bioavailability of ciclosporin by intravenous pulse of methylprednisolone succinate in rats.

Journal: The Journal of pharmacy and pharmacology20041001

Title: The bioavailability of IV methylprednisolone and oral prednisone in multiple sclerosis.

Journal: Neurology20040928

Title: Effects of MPSS and a potent iNOS inhibitor on traumatic spinal cord injury.

Journal: Neuroreport20040915

Title: Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury.

Journal: International journal of clinical pharmacology and therapeutics20040901

Title: Methylprednisolone sodium succinate in pediatric parenteral nutrition: influence of vehicle injection.

Journal: Clinical nutrition (Edinburgh, Scotland)20040801

Title: Acute bullous eruption with compartment syndrome due to intravenous infiltration.

Journal: Archives of dermatology20040701

Title: [Mantle cell lymphoma markedly infiltrated into adrenal glands with adrenal insufficiency].

Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology20040701

Title: Effects of duration of ischemia and donor pretreatment with methylprednisolone or its macromolecular prodrug on the disposition of indocyanine green in cold-preserved rat livers.

Journal: Pharmaceutical research20040601

Title: Serum sickness-like reaction and bupropion.

Journal: Journal of the American Academy of Child and Adolescent Psychiatry20040501

Title: Clinical presentation, natural history, and treatment of crescentic proliferative IgA nephropathy.

Journal: Seminars in nephrology20040501

Title: Acute traumatic spinal cord injury, 1993-2000A population-based assessment of methylprednisolone administration and hospitalization.

Journal: The Journal of trauma20040501

Title: Comparison of methylprednisolone with dexamethasone in treatment of acute spinal injury in rats.

Journal: Indian journal of experimental biology20040501

Title: Influence of intravenous methylprednisolone pulse treatment on the disposition of ciclosporin and hepatic CYP3A activity in rats.

Journal: The Journal of pharmacy and pharmacology20040401

Title: Effects of corticosteroids on inflammatory response following cardiopulmonary bypass.

Journal: Croatian medical journal20040401

Title: Central retinal artery occlusion as the initial ophthalmic presentation of Susac's syndrome.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie20040401

Title: Anaphylaxis following administration of intravenous methylprednisolone sodium succinate in a renal transplant recipient.

Journal: International journal of urology : official journal of the Japanese Urological Association20040301

Title: [Orbital extension of sinus plasmacytoma secondarily transforming into multiple myeloma: a case study].

Journal: Journal francais d'ophtalmologie20040101

Title: Update on pharmaceutical trials in acute spinal cord injury.

Journal: The journal of spinal cord medicine20040101

Title: Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.

Journal: Internal medicine (Tokyo, Japan)20031201

Title: [Wegener's granulomatosis (morbus Wegener)].

Journal: Praxis20031112

Title: Interstitial pneumonitis induced by bicalutamide and leuprorelin acetate for prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association20031101

Title: What's wrong with this patient? POEMS syndrome.

Journal: RN20031101

Title: Intraoperative solumedrol helps prevent postpneumonectomy pulmonary edema.

Journal: The Annals of thoracic surgery20031001

Title: Decreased bone mineral density in the pediatric renal transplant population.

Journal: Pediatric transplantation20031001

Title: Intravenous corticosteroids to reduce gemtuzumab ozogamicin infusion reactions.

Journal: The Annals of pharmacotherapy20030901

Title: Salvage chemotherapy according to the ASHAP protocol: a single-center study of 24 patients with relapsed or refractory aggressive non-Hodgkin's lymphomas.

Journal: Annals of hematology20030801

Title: Crescentic, proliferative IgA nephropathy: clinical and histological response to methylprednisolone and intravenous cyclophosphamide.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20030701

Title: High- and low-risk profiles for the development of multiple sclerosis within 10 years after optic neuritis: experience of the optic neuritis treatment trial.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20030701

Title: Steroid-free immunosuppression during and after liver transplantation--a 3-yr follow-up report.

Journal: Clinical transplantation20030601

Title: Hypersensitivity and idiosyncratic reactions to oxaliplatin.

Journal: Cancer20030501

Title: Severe acute respiratory syndrome. The Mount Sinai experience.

Journal: The Canadian nurse20030501

Title: An 89-year-old woman with angioedema during t-PA infusion for acute ischemic stroke.

Journal: Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association20030401

Title: High-dose steroids, ursodeoxycholic acid, and chronic intravenous antibiotics improve bile flow after Kasai procedure in infants with biliary atresia.

Journal: Journal of pediatric surgery20030301

Title: The 'crashing asthmatic.'.

Journal: American family physician20030301

Title: [Graves' ophthalmopathy: diagnosis and highlights on etiopathogenesis and treatment].

Journal: La Tunisie medicale20030301

Title: Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: local immunosuppressive effects in liver after systemic administration to rats.

Journal: Pharmaceutical research20030201

Title: Acute posterior multifocal placoid pigment epitheliopathy associated with a systemic necrotizing vasculitis.

Journal: Retina (Philadelphia, Pa.)20030201

Title: [Side effects during treatment with Solu-Medrol for optic neuritis in the course of MS].

Journal: Klinika oczna20030101

Title: Degradation of methylprednisolone sodium succinate in a diluent-containing vial.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20021215

Title: IgE-mediated anaphylactic reaction induced by succinate ester of methylprednisolone.

Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology20021001

Title: Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20020815

Title: Subtenon's depot corticosteroid injections in patients with a history of corticosteroid-induced intraocular pressure elevation.

Journal: American journal of ophthalmology20020201

Title: Stevens-Johnson syndrome developing in a girl with systemic lupus erythematosus on high-dose corticosteroid therapy.

Journal: Pediatric dermatology20020101

Title: Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels.

Journal: Experimental eye research20020101

Title: Effect of steroids on lipopolysaccharide/interleukin 2-induced interleukin 18 production in peripheral blood mononuclear cells.

Journal: The Journal of international medical research20020101

Title: Partial reversal of methylprednisolone-induced opacity in isolated rat lenses.

Journal: Ophthalmic research20020101

Title: Steroids for acute spinal cord injury.

Journal: The Cochrane database of systematic reviews20020101

Title: Stevens-Johnson syndrome: case presentation.

Journal: The Journal of clinical pediatric dentistry20020101

Title: Stability of methylprednisolone sodium succinate in autodose infusion system bags.

Journal: Journal of the American Pharmaceutical Association (Washington,D.C. : 1996)20020101

Title: Dextran-methylprednisolone succinate as a prodrug of methylprednisolone: plasma and tissue disposition.

Journal: Journal of pharmaceutical sciences20011201

Title: Effect of short-course, high-dose steroid therapy in a child with myelodysplastic syndrome.

Journal: Pediatric hematology and oncology20011201

Title: Systemic steroid pretreatment improves cerebral protection after circulatory arrest.

Journal: The Annals of thoracic surgery20011101

Title: Preoperative administration of steroids: influence on adhesion molecules and cytokines after cardiopulmonary bypass.

Journal: The Annals of thoracic surgery20011001

Title: The effects of glucocorticoid therapy on inflammatory responses to coronary artery bypass graft surgery.

Journal: Archives of surgery (Chicago, Ill. : 1960)20010901

Title: Radiation therapy after a partial response to CHOP chemotherapy for aggressive lymphomas.

Journal: International journal of radiation oncology, biology, physics20010701

Title: Corticosteroids alter the differentiated phenotype of articular chondrocytes.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society20010701

Title: Stability of methylprednisolone sodium succinate in pediatric parenteral nutrition mixtures.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists20010615

Title: Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone.

Journal: Journal of neurochemistry20010501

Title: Effects of preoperative steroid administration on surgical stress in hepatic resection: prospective randomized trial.

Journal: Archives of surgery (Chicago, Ill. : 1960)20010301

Title: Methylprednisolone does not benefit patients undergoing coronary artery bypass grafting and early tracheal extubation.

Journal: The Journal of thoracic and cardiovascular surgery20010301

Title: [Central serous chorioretinopathy and systemic steroid therapy].

Journal: Journal francais d'ophtalmologie20010201

Title: Methylprednisolone concentrations in the vitreous and the serum after pulse therapy.

Journal: Retina (Philadelphia, Pa.)20010101

Title: Induction strategy using basiliximab combined with mycophenolate MMF and immediate low-dose cyclosporin is steroid sparing and more effective than OKT3.

Journal: Transplantation proceedings20010101

Title: Pulse methylprednisolone therapy for arthritis causing muscle weakness.

Journal: Annals of the rheumatic diseases19990901

Title: Acute interstitial nephritis following treatment with anorectic agents phentermine and phendimetrazine.

Journal: Clinical nephrology19981001

Title: Steroid-pulse therapy in pemphigus vulgaris long term follow-up.

Journal: International journal of dermatology19950601

Title: Decreased vitamin B12 and folate levels in cerebrospinal fluid and serum of multiple sclerosis patients after high-dose intravenous methylprednisolone.

Journal: Journal of neurology19930501

Title: Systemic allergic reactions to corticosteroids.

Journal: The Journal of asthma : official journal of the Association for the Care of Asthma19910101

Title: Fatal acute pyelonephritis following pulsed methylprednisolone for rheumatoid arthritis.

Journal: Annals of the rheumatic diseases19901101

Title: Dapsone hepatitis.

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Title: Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy.

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Title: An attempt to develop a model to study the effects of intrathecal steroids.

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Title: Intractable hiccups associated with high-dose intravenous methylprednisolone therapy.

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Title: Positive synergism between diuretics and methylprednisolone following acute myocardial infarction.

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