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53003-10-4,MFCD25541652
Catalog No.:AA019FPV

53003-10-4 | Salinomycin

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5mg
≥90%
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$36.00   $25.00
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10mg
≥90%
in stock  
$53.00   $37.00
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50mg
≥90%
in stock  
$135.00   $94.00
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100mg
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA019FPV
Chemical Name:
Salinomycin
CAS Number:
53003-10-4
Molecular Formula:
C42H70O11
Molecular Weight:
750.9986
MDL Number:
MFCD25541652
SMILES:
CC[C@H]([C@H]1O[C@]2(C=C[C@H]([C@@]3(O2)CC[C@@](O3)(C)[C@H]2CC[C@]([C@@H](O2)C)(O)CC)O)[C@@H](C[C@@H]1C)C)C(=O)[C@H]([C@H]([C@@H]([C@@H]1O[C@H](CC[C@@H]1C)[C@H](C(=O)O)CC)C)O)C
Properties
Computed Properties
 
Complexity:
1320  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
18  
Heavy Atom Count:
53  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
12  
XLogP3:
5.7  

Literature

Title: Salinomycin induces primary chicken cardiomyocytes death via mitochondria mediated apoptosis.

Journal: Chemico-biological interactions 20180225

Title: Salinomycin attenuates liver cancer stem cell motility by enhancing cell stiffness and increasing F-actin formation via the FAK-ERK1/2 signalling pathway.

Journal: Toxicology 20170601

Title: Salinomycin suppresses TGF-β1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells.

Journal: Chemico-biological interactions 20160325

Title: Preclinical drug metabolism and pharmacokinetics of salinomycin, a potential candidate for targeting human cancer stem cells.

Journal: Chemico-biological interactions 20151005

Title: Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling.

Journal: Chemico-biological interactions 20150225

Title: Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides.

Journal: Molecules (Basel, Switzerland) 20141125

Title: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.

Journal: Toxicology letters 20131024

Title: Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells.

Journal: International journal of cancer 20121215

Title: Antiproliferative activity of salinomycin and its derivatives.

Journal: Bioorganic & medicinal chemistry letters 20121201

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Effects of the veterinary pharmaceutical salinomycin and its formulation on the plant Brassica rapa.

Journal: Archives of environmental contamination and toxicology 20121101

Title: Effects of anticoccidial and antibiotic growth promoter programs on broiler performance and immune status.

Journal: Research in veterinary science 20121001

Title: Sorption and desorption of salinomycin sodium in clay, loamy sand, and sandy soils.

Journal: Environmental monitoring and assessment 20120901

Title: Detection and quantitative analysis of 21 veterinary drugs in river water using high-pressure liquid chromatography coupled to tandem mass spectrometry.

Journal: Environmental science and pollution research international 20120901

Title: Effects of nicarbazin on the blood glucose and liver glycogen statuses of male broilers.

Journal: Poultry science 20120901

Title: Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest.

Journal: Investigational new drugs 20120801

Title: Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic-salinomycin.

Journal: Bioorganic & medicinal chemistry letters 20120715

Title: Simultaneous determination of human and veterinary antibiotics in various environmental matrices by rapid resolution liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal: Journal of chromatography. A 20120629

Title: Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.

Journal: Cell 20120608

Title: Cancer stem cells and metastasis.

Journal: Seminars in cancer biology 20120601

Title: Effects of sodium butyrate and salinomycin upon intestinal microbiota, mucosal morphology and performance of broiler chickens.

Journal: Archives of animal nutrition 20120401

Title: Salinomycin: a new cancer drug candidate.

Journal: Chemical biology & drug design 20120301

Title: Salinomycin toxicity causes deaths of calves on two Scottish dairy farms.

Journal: The Veterinary record 20120204

Title: Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest.

Journal: Biochemical and biophysical research communications 20120203

Title: Comparison of the oral bioavailability and tissue disposition of monensin and salinomycin in chickens and turkeys.

Journal: Journal of veterinary pharmacology and therapeutics 20120201

Title: Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress.

Journal: British journal of cancer 20120103

Title: A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.

Journal: Chembiochem : a European journal of chemical biology 20120102

Title: The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer.

Journal: Journal of cellular biochemistry 20120101

Title: The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles.

Journal: Biomaterials 20120101

Title: Biotic transformation of anticoccidials in soil using a lab-scale bio-reactor as a precursor-tool.

Journal: Chemosphere 20120101

Title: Simultaneous determination of five polyether ionophores using liquid chromatography with one-step fluorescent derivatization.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

Title: Report on the 3'rd scientific meeting of the 'Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie' (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011.

Journal: Experimental & translational stroke medicine 20120101

Title: Cancer stem cells and novel targets for antitumor strategies.

Journal: Current pharmaceutical design 20120101

Title: Correlation coefficients between different methods of expressing bacterial quantification using real time PCR.

Journal: International journal of molecular sciences 20120101

Title: Enhancing effects on vacuole-targeting fungicidal activity of amphotericin B.

Journal: Frontiers in microbiology 20120101

Title: Curcumin: updated molecular mechanisms and intervention targets in human lung cancer.

Journal: International journal of molecular sciences 20120101

Title: Anticoccidial effect of supplemental dietary Galla Rhois against infection with Eimeria tenella in chickens.

Journal: Avian pathology : journal of the W.V.P.A 20120101

Title: Quantification of ionophores in aged poultry litter using liquid chromatography tandem mass spectrometry.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101

Title: Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24.

Journal: Journal of AOAC International 20120101

Title: Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International 20120101

Title: Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species.

Journal: PloS one 20120101

Title: Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro.

Journal: BMC cancer 20120101

Title: Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells.

Journal: Cancer letters 20111227

Title: In vitro destruction of Eimeria oocysts by essential oils.

Journal: Veterinary parasitology 20111215

Title: Salinomycin inhibits osteosarcoma by targeting its tumor stem cells.

Journal: Cancer letters 20111201

Title: Antimicrobial susceptibilities of Listeria monocytogenes isolated in Japan.

Journal: The Journal of veterinary medical science 20111201

Title: Development and validation of an UPLC-MS/MS method for the determination of ionophoric and synthetic coccidiostats in vegetables.

Journal: Analytical and bioanalytical chemistry 20111201

Title: Salinomycin toxicity in dairy calves.

Journal: The Veterinary record 20111119

Title: Lower prevalence of antibiotic-resistant Enterococci on U.S. conventional poultry farms that transitioned to organic practices.

Journal: Environmental health perspectives 20111101

Title: Species characterization and minimum inhibitory concentration patterns of Brachyspira species isolates from swine with clinical disease.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20111101

Title: Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20111001

Title: Multiple-antibiotic resistance of Enterococcus faecalis and Enterococcus faecium from cecal contents in broiler chicken and turkey flocks slaughtered in Canada and plasmid colocalization of tetO and ermB genes.

Journal: Journal of food protection 20111001

Title: Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization.

Journal: Biochemical and biophysical research communications 20110916

Title: Rapid quantification of ionophores in feeds by liquid chromatography-tandem mass spectrometry.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110901

Title: Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.

Journal: Analytica chimica acta 20110826

Title: Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.

Journal: Analytica chimica acta 20110826

Title: Inhibition of Wnt signaling and cancer stem cells.

Journal: Oncotarget 20110801

Title: Unraveling the complexity of basal-like breast cancer.

Journal: Oncotarget 20110801

Title: Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas.

Journal: Cell cycle (Georgetown, Tex.) 20110615

Title: Salinomycin selectively targets 'CD133+' cell subpopulations and decreases malignant traits in colorectal cancer lines.

Journal: Annals of surgical oncology 20110601

Title: Microbial community and metabolomic comparison of irritable bowel syndrome faeces.

Journal: Journal of medical microbiology 20110601

Title: Salinomycin induces calpain and cytochrome c-mediated neuronal cell death.

Journal: Cell death & disease 20110601

Title: Anticoccidial effects of coumestans from Eclipta alba for sustainable control of Eimeria tenella parasitosis in poultry production.

Journal: Veterinary parasitology 20110419

Title: Susceptibility of Clostridium difficile toward antimicrobial agents used as feed additives for food animals.

Journal: Microbial drug resistance (Larchmont, N.Y.) 20110301

Title: Effects of salinomycin on cancer stem cell in human lung adenocarcinoma A549 cells.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20110301

Title: Rapid and reliable identification of ionophore antibiotics in feeds by liquid chromatography-tandem mass spectrometry.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110301

Title: The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites.

Journal: Avian diseases 20110301

Title: Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein.

Journal: British journal of pharmacology 20110201

Title: Eradicating cancer cells: struggle with a chameleon.

Journal: Oncotarget 20110201

Title: Megacities as sources for pathogenic bacteria in rivers and their fate downstream.

Journal: International journal of microbiology 20110101

Title: Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors.

Journal: Journal of oncology 20110101

Title: Cooperation of cancer stem cell properties and epithelial-mesenchymal transition in the establishment of breast cancer metastasis.

Journal: Journal of oncology 20110101

Title: Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters.

Journal: BMC cancer 20110101

Title: Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity.

Journal: PloS one 20110101

Title: Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.

Journal: Breast cancer research : BCR 20110101

Title: Evaluation of Iron-induced Oxidative Stress and its Amelioration by Certain Herbs in Broilers.

Journal: Toxicology international 20110101

Title: Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer).

Journal: Gene regulation and systems biology 20110101

Title: A new approach to the analysis of nicarbazin and ionophores in eggs by HPLC/MS/MS.

Journal: Journal of AOAC International 20110101

Title: Effect of Antibiotic Growth Promoters on Intestinal Microbiota in Food Animals: A Novel Model for Studying the Relationship between Gut Microbiota and Human Obesity?

Journal: Frontiers in microbiology 20110101

Title: Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin.

Journal: Chemistry Central journal 20110101

Title: Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms.

Journal: PloS one 20110101

Title: Impacts of poultry house environment on poultry litter bacterial community composition.

Journal: PloS one 20110101

Title: Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity.

Journal: Breast cancer research : BCR 20110101

Title: Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway.

Journal: PloS one 20110101

Title: Simultaneous determination of polyether ionophores, macrolides and lincosamides in hen eggs by liquid chromatography-electrospray ionization tandem mass spectrometry using a simple solvent extraction.

Journal: Analytica chimica acta 20101203

Title: Biodegradation of polyether algal toxins--isolation of potential marine bacteria.

Journal: Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20101201

Title: Effects of ionophores on liver CYP1A and 3A in male broilers.

Journal: Journal of veterinary pharmacology and therapeutics 20101201

Title: Accidental salinomycin intoxication in calves.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20101001

Title: Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors.

Journal: Gastroenterology 20100901

Title: Identification and quantification of salinomycin in intoxicated human plasma by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20100901

Title: Comparison of Eimeria species distribution and salinomycin resistance in commercial broiler operations utilizing different coccidiosis control strategies.

Journal: Avian diseases 20100901

Title: Selection of single chain variable fragment (scFv) antibodies from a hyperimmunized phage display library for the detection of the antibiotic monensin.

Journal: Journal of immunological methods 20100831

Title: Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens.

Journal: Parasitology research 20100801

Title: The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor.

Journal: Blood cells, molecules & diseases 20100615

Title: Interference free detection for small molecules: probing the Mn2+-doped effect and cysteine capped effect on the ZnS nanoparticles for coccidiostats and peptide analysis in SALDI-TOF MS.

Journal: The Analyst 20100501

Title: Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells.

Journal: Biochemical and biophysical research communications 20100416

Title: The effect of composting on the degradation of a veterinary pharmaceutical.

Journal: Bioresource technology 20100401

Title: The effect of commonly used anticoccidials and antibiotics in a subclinical necrotic enteritis model.

Journal: Avian pathology : journal of the W.V.P.A 20100201

Title: Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction.

Journal: Organic & biomolecular chemistry 20100107

Title: Veterinary pharmaceuticals and antibiotic resistance of Escherichia coli isolates in poultry litter from commercial farms and controlled feeding trials.

Journal: Poultry science 20100101

Title: Retrospective study of salinomycin toxicosis in 66 cats.

Journal: Veterinary medicine international 20100101

Title: Comparative efficacy of an organic Acid blend and bacitracin methylene disalicylate as growth promoters in broiler chickens: effects on performance, gut histology, and small intestinal milieu.

Journal: Veterinary medicine international 20100101

Title: Biosynthesis and molecular genetics of polyketides in marine dinoflagellates.

Journal: Marine drugs 20100101

Title: Pathway signature and cellular differentiation in clear cell renal cell carcinoma.

Journal: PloS one 20100101

Title: Isolation of deoxynivalenol-transforming bacteria from the chicken intestines using the approach of PCR-DGGE guided microbial selection.

Journal: BMC microbiology 20100101

Title: Cancerous stem cells: deviant stem cells with cancer-causing misbehavior.

Journal: Stem cell research & therapy 20100101

Title: Targeting breast cancer stem cells: fishing season open!

Journal: Breast cancer research : BCR 20100101

Title: Increasing CD44+/CD24(-) tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis.

Journal: Molecular cancer 20100101

Title: The regulation of miRNA-211 expression and its role in melanoma cell invasiveness.

Journal: PloS one 20100101

Title: Modeling the clonal heterogeneity of stem cells.

Journal: Theoretical biology & medical modelling 20100101

Title: Oxidative stress induced by lead and antioxidant potential of certain adaptogens in poultry.

Journal: Toxicology international 20100101

Title: Markers of tumor-initiating cells predict chemoresistance in breast cancer.

Journal: PloS one 20100101

Title: Salinomycin in cancer: A new mission for an old agent.

Journal: Molecular medicine reports 20100101

Title: Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells.

Journal: Biochemical and biophysical research communications 20091218

Title: Effects and mechanisms of action of ionophorous antibiotics valinomycin and salinomycin-Na on Babesia gibsoni in vitro.

Journal: The Journal of parasitology 20091201

Title: Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC.

Journal: Journal of chromatography. A 20091113

Title: Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: High-throughput screening finds potential killer of cancer stem cells.

Journal: Journal of the National Cancer Institute 20091104

Title: The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review.

Journal: Poultry science 20091101

Title: New drug against cancer stem cells may prevent disease recurrence and spread.

Journal: ONS connect 20091101

Title: [Determination of 5 polyether antibiotics in chicken tissues by liquid chromatography-electrospray ionization tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20091101

Title: Evaluation of PCR and DNA sequencing for direct detection of Clostridium perfringens in the intestinal tract of broilers.

Journal: Avian diseases 20090901

Title: Determination of veterinary pharmaceuticals in poultry litter and soil by methanol extraction and liquid chromatography-tandem mass spectrometry.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090901

Title: Identification of selective inhibitors of cancer stem cells by high-throughput screening.

Journal: Cell 20090821

Title: Taking aim at aggressive cancer cells.

Journal: Cancer biology & therapy 20090801

Title: The role of probiotics in the poultry industry.

Journal: International journal of molecular sciences 20090801

Title: Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms.

Journal: Poultry science 20090701

Title: Incidence of animal poisoning cases in the Czech Republic: current situation.

Journal: Interdisciplinary toxicology 20090601

Title: Fast liquid chromatography/multiple-stage mass spectrometry of coccidiostats.

Journal: Rapid communications in mass spectrometry : RCM 20090501

Title: Disruption of a mitochondrial MutS DNA repair enzyme homologue confers drug resistance in the parasite Toxoplasma gondii.

Journal: Molecular microbiology 20090401

Title: Diversity and susceptibility of Enterococcus isolated from cattle before and after harvest.

Journal: Journal of food protection 20090401

Title: Monoclonal antibody production and immunochemical detection of polyether antibiotics.

Journal: Archives of pharmacal research 20090301

Title: Fate and antibacterial potency of anticoccidial drugs and their main abiotic degradation products.

Journal: Environmental pollution (Barking, Essex : 1987) 20090201

Title: Synergistic fungicidal activities of polymyxin B and ionophores, and their dependence on direct disruptive action of polymyxin B on fungal vacuole.

Journal: The Journal of antibiotics 20090201

Title: Effects of salinomycin on cell-mediated immunity of broiler chickens against hydropericardium syndrome and Newcastle disease viruses.

Journal: Poultry science 20090101

Title: Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027.

Journal: BMC microbiology 20090101

Title: Occurrence and elimination of antibiotics at four sewage treatment plants in Japan and their effects on bacterial ammonia oxidation.

Journal: Water science and technology : a journal of the International Association on Water Pollution Research 20090101

Title: Dietary supplementation of mannan-oligosaccharide enhances neonatal immune responses in chickens during natural exposure to Eimeria spp.

Journal: Acta veterinaria Scandinavica 20090101

Title: Responses of plasma acetate metabolism to hop (Humulus lupulus L.) in sheep.

Journal: International journal of biological sciences 20090101

Title: Synthetic lethality: a framework for the development of wiser cancer therapeutics.

Journal: Genome medicine 20090101

Title: Epithelial to mesenchymal transition and breast cancer.

Journal: Breast cancer research : BCR 20090101

Title: [Salinomycin and semduramicin in different concentrations on the broilers eimeriosis control].

Journal: Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20090101

Title: Compatibility of a combination of tiamulin and chlortetracycline with salinomycin in feed during a pulsed medication program coadministration in broilers.

Journal: Poultry science 20081201

Title: Characterization of Streptomyces spp. isolated from the sea surface microlayer in the Trondheim Fjord, Norway.

Journal: Marine drugs 20081201

Title: Investigation of chicken intestinal bacterial communities by 16S rRNA targeted fluorescence in situ hybridization.

Journal: Antonie van Leeuwenhoek 20081001

Title: Determination of ionophore coccidiostats in feedingstuffs by liquid chromatography-tandem mass spectrometry Part I. Application to targeted feed.

Journal: Journal of pharmaceutical and biomedical analysis 20080805

Title: Compatibility of a combination of tiamulin plus chlortetracycline with salinomycin in feed during a long-term co-administration in broilers.

Journal: Poultry science 20080801

Title: Pharmacological evaluation of contractile activity of the dog heartworm Dirofilaria immitis.

Journal: Veterinary research communications 20080301

Title: Natural Products and Medicinal Chemistry--the 22nd Mona Symposium.

Journal: IDrugs : the investigational drugs journal 20080301

Title: Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles.

Journal: Journal of the American Chemical Society 20071205

Title: Effects of polyether ionophores on the protective immune responses of broiler chickens against Angara disease and Newcastle disease viruses.

Journal: Veterinary research communications 20071001

Title: Liquid chromatography-tandem mass spectrometric assays for salinomycin in mouse plasma, liver, brain and small intestinal contents and in OptiMEM cell culture medium.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815

Title: Salinomycin toxicosis in horses.

Journal: Journal of the American Veterinary Medical Association 20070615

Title: Direct-fed microbial PrimaLac and salinomycin modulate whole-body and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick.

Journal: Poultry science 20070601

Title: Microarchitecture and spatial relationship between bacteria and ileal, cecal, and colonic epithelium in chicks fed a direct-fed microbial, PrimaLac, and salinomycin.

Journal: Poultry science 20070601

Title: An integrated sample preparation to determine coccidiostats and emerging Fusarium-mycotoxins in various poultry tissues with LC-MS/MS.

Journal: Molecular nutrition & food research 20070501

Title: Efficacy of some anticoccidial drugs for treating coccidial enteritis of the common carp caused by Goussia carpelli (Apicomplexa: Eimeriidae).

Journal: Acta veterinaria Hungarica 20070301

Title: Evaluation of the efficacy of a probiotic containing Lactobacillus, Bifidobacterium, Enterococcus, and Pediococcus strains in promoting broiler performance and modulating cecal microflora composition and metabolic activities.

Journal: Poultry science 20070201

Title: Impact of salinomycin on the intestinal microflora of broiler chickens.

Journal: Acta veterinaria Scandinavica 20070101

Title: Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719.

Journal: Folia microbiologica 20070101

Title: Prevalence and antimicrobial resistance of enterococci isolated from retail fruits, vegetables, and meats.

Journal: Journal of food protection 20061201

Title: Persistence of antibiotics such as macrolides, tiamulin and salinomycin in soil.

Journal: Environmental pollution (Barking, Essex : 1987) 20061001

Title: Increased level of Eimeria sensitivity to diclazuril after using a live coccidial vaccine.

Journal: Avian diseases 20060901

Title: Elimination of macrolides, tiamulin, and salinomycin during manure storage.

Journal: Archives of environmental contamination and toxicology 20060701

Title: Occurrence of ionophore antibiotics in water and sediments of a mixed-landscape watershed.

Journal: Water research 20060701

Title: Microbial community composition of the ileum and cecum of broiler chickens as revealed by molecular and culture-based techniques.

Journal: Poultry science 20060701

Title: Evaluation of a Bacillus stearothermophilus tube test as a screening tool for anticoccidial residues in poultry.

Journal: Journal of veterinary science 20060601

Title: Effect of dietary zinc level on serum carotenoid levels, body and shank pigmentation of chickens after experimental infection with coccidia.

Journal: Archives of animal nutrition 20060601

Title: Simultaneous determination of four coccidiostats in eggs and broiler meat: validation of an LC-MS/MS method.

Journal: Food additives and contaminants 20060501

Title: A case of salinomycin intoxication in turkeys.

Journal: The Canadian veterinary journal = La revue veterinaire canadienne 20060301

Title: Stereoselective synthesis of the western hemisphere of salinomycin.

Journal: Organic letters 20060202

Title: Tiamulin resistance in porcine Brachyspira pilosicoli isolates.

Journal: Research in veterinary science 20060201

Title: Determination of monensin, narasin, and salinomycin in mineral premixes, supplements, and animal feeds by liquid chromatography and post-column derivatization: collaborative study.

Journal: Journal of AOAC International 20060101

Title: Combined effect of salinomycin and feeding on whole body glucose kinetics in sheep fed a high-concentrate diet.

Journal: Reproduction, nutrition, development 20060101

Title: [The effect of betain on biology and morphology of developmental stages of Eimeria acervulina in broiler chicks experimentally infected].

Journal: Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20060101

Title: Antiparasitic and immunomodulatory effect of innovative treatments against Myxobolus sp. infection in Diplodus puntazzo.

Journal: Veterinary parasitology 20051210

Title: Incidence of residues of nine anticoccidials in eggs.

Journal: Food additives and contaminants 20051101

Title: HPLC determination of salinomycin and related compounds in fermentation media of Streptomyces albus and premixes.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents.

Journal: Bioorganic & medicinal chemistry letters 20050701

Title: Effects of Natustat supplementation on performance, feed efficiency and intestinal lesion scores in broiler chickens challenged with Eimeria acervulina, Eimeria maxima and Eimeria tenella.

Journal: Veterinary parasitology 20050630

Title: Rapid analysis of trace levels of antibiotic polyether ionophores in surface water by solid-phase extraction and liquid chromatography with ion trap tandem mass spectrometric detection.

Journal: Journal of chromatography. A 20050218

Title: Performance and nutrient retention responses of broilers to dietary oxyhalogenic and ionic salts.

Journal: Poultry science 20050201

Title: Determination of the ionophoric coccidiostats narasin, monensin, lasalocid and salinomycin in eggs by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: The impact of a successful anti-myxosporean treatment on the phagocyte functions of juvenile and adult Sparus aurata L.

Journal: International journal of immunopathology and pharmacology 20050101

Title: Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

Title: Efficacy and toxicity of orally administrated anti-coccidial drugs for innovative treatments of Myxobolus sp. infection in Puntazzo puntazzo.

Journal: Diseases of aquatic organisms 20041213

Title: Development of multiclass methods for drug residues in eggs: silica SPE cleanup and LC-MS/MS analysis of ionophore and macrolide residues.

Journal: Journal of agricultural and food chemistry 20041117

Title: An unaddressed issue of agricultural terrorism: a case study on feed security.

Journal: Journal of animal science 20041101

Title: Radical oxidative cyclization of spiroacetals to bis-spiroacetals: an overview.

Journal: Molecules (Basel, Switzerland) 20040531

Title: Coccidiosis control by administering toltrazuril in the drinking water for a 2-day period.

Journal: Veterinary parasitology 20040507

Title: The effects of salinomycin and roxarsone on the performance of broilers when included in the feed for four, five, or six weeks and infected with Eimeria species during the starter or grower phase of production.

Journal: Poultry science 20040501

Title: Rapid time-resolved fluoroimmunoassay for the screening of narasin and salinomycin residues in poultry and eggs.

Journal: Journal of agricultural and food chemistry 20040407

Title: Further characterization of porcine Brachyspira hyodysenteriae isolates with decreased susceptibility to tiamulin.

Journal: Journal of medical microbiology 20040401

Title: [Inhibitory effect of zinc on beta-hexosaminidase release from RBL-2H3 cells by synthetic chemicals].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20040401

Title: A case of human poisoning by salinomycin, an agricultural antibiotic.

Journal: The New Zealand medical journal 20040312

Title: Isolation and selection of ionophore-tolerant Eimeria precocious lines: E. tenella, E. maxima and E. acervulina.

Journal: Veterinary parasitology 20040206

Title: A field study on the effect of the dietary use of a clinoptilolite-rich tuff, alone or in combination with certain antimicrobials, on the health status and performance of weaned, growing and finishing pigs.

Journal: Research in veterinary science 20040201

Title: Susceptibility of Clostridium perfringens strains from broiler chickens to antibiotics and anticoccidials.

Journal: Avian pathology : journal of the W.V.P.A 20040201

Title: Evaluation of zinc against salinomycin toxicity in broilers.

Journal: Indian journal of physiology and pharmacology 20040101

Title: Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations.

Journal: Avian diseases 20040101

Title: Comparison of microwave assisted extraction with conventional (homogenization, vortexing) for the determination of incurred salinomycin in chicken eggs and tissues.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040101

Title: Growth enhancement in broiler chickens receiving CHEMEQRTM polymeric antimicrobial.

Journal: Avian pathology : journal of the W.V.P.A 20031201

Title: Identification of new leishmanicidal peptide lead structures by automated real-time monitoring of changes in intracellular ATP.

Journal: The Biochemical journal 20031001

Title: Ionophores: their use as ruminant growth promotants and impact on food safety.

Journal: Current issues in intestinal microbiology 20030901

Title: Cloning of modular type I polyketide synthase genes from salinomycin producing strain of Streptomyces albus.

Journal: Bioorganic & medicinal chemistry 20030805

Title: Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001.

Journal: Avian pathology : journal of the W.V.P.A 20030801

Title: Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. A 20030627

Title: Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss.

Journal: Diseases of aquatic organisms 20030620

Title: Pancreatic lipase activity as influenced by unconjugated bile acids and pH, measured in vitro and in vivo.

Journal: The Journal of nutritional biochemistry 20030501

Title: Antimicrobial growth promoters and Salmonella spp., Campylobacter spp. in poultry and swine, Denmark.

Journal: Emerging infectious diseases 20030401

Title: Determination of antibiotics such as macrolides, ionophores and tiamulin in liquid manure by HPLC-MS/MS.

Journal: Analytical and bioanalytical chemistry 20030401

Title: LC determination of salinomycin in fermentation broths and premixes.

Journal: Journal of pharmaceutical and biomedical analysis 20030226

Title: Fragmentation study of salinomycin and monensin A antibiotics using electrospray quadrupole time-of-flight mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20030101

Title: Degradation of tryptophan and related indolic compounds by ruminal bacteria, protozoa and their mixture in vitro.

Journal: Amino acids 20030101

Title: Antimicrobial susceptibilities of Staphylococcus aureus isolated from commercial broilers in northeastern Georgia.

Journal: Avian diseases 20030101

Title: Coccidiosis control with toltrazuril in conjunction with anticoccidial medicated or nonmedicated feed.

Journal: Avian diseases 20030101

Title: Beneficial effect of beta-mannanase feed enzyme on performance of chicks challenged with Eimerla sp. and Clostridium perfringens.

Journal: Avian diseases 20030101

Title: A new method for in vitro detection of microbially produced mitochondrial toxins.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20030101

Title: [Effects of veterinary drugs on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3)].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021001

Title: Effects of orally administered chemotherapeutics (quinine, salinomycin) against Henneguya sp. Thelohán, 1892 (Myxozoa: Myxobolidae), a gill parasite in the tapir fish Gnathonemus petersii Günther, 1862 (Teleostei).

Journal: Parasitology research 20020901

Title: Potentiometric determination of polyether ionophores growth promotors in animal feed preparations.

Journal: Journal of pharmaceutical and biomedical analysis 20020720

Title: The determination of 5 anticoccidial drugs (nicarbazin, lasalocid, monensin, salinomycin and narasin) in animal livers and eggs by liquid chromatography linked with tandem mass spectrometry (LC-MS-MS).

Journal: The Analyst 20020601

Title: The use of diclazuril in extended withdrawal anticoccidial programs: 1. Efficacy against Eimeria spp. in broiler chickens in floor pens.

Journal: Poultry science 20020301

Title: Effect of antibiotics on in vitro and in vivo avian cartilage degradation.

Journal: Avian diseases 20020101

Title: Recovery of injured adrenal medulla by differentiation of pre-existing undifferentiated chromaffin cells.

Journal: Toxicologic pathology 20020101

Title: Study of resistance against some ionophores in Eimeria tenella field isolates.

Journal: Veterinary parasitology 20011203

Title: Efficient and sensitive screening and confirmation of residues of selected polyether ionophore antibiotics in liver and eggs by liquid chromatography-electrospray tandem mass spectrometry.

Journal: The Analyst 20011101

Title: Salinomycin poisoning in veal calves.

Journal: The Veterinary record 20010811

Title: The effect of salinomycin on certain blood parameters and milk quality of lactating sows.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010801

Title: The effect of salinomycin on health status and performance of sows and their litters: a dose titration study.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010601

Title: Use of anticoccidial drugs in broiler chickens in the USA: analysis for the years 1995 to 1999.

Journal: Poultry science 20010501

Title: Efficacy of diclazuril in comparison with chemical and ionophorous anticoccidials against Eimeria spp. in broiler chickens in floor pens.

Journal: Poultry science 20010401

Title: Polyether antibiotic CP44,161.

Journal: Acta crystallographica. Section C, Crystal structure communications 20010101

Title: [Oxadin effect on actinomycetes strains].

Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101

Title: LC/MS confirmation of ionophores in animal feeds.

Journal: Journal of AOAC International 20010101

Title: Comparative investigation of salinomycin and flavophospholipol in sheep fed different composed diets.

Journal: Archiv fur Tierernahrung 20010101

Title: Anticryptosporidial activity of lasalocid and other ionophorous antibiotics in immunosuppressed rats.

Journal: The Journal of infectious diseases 19931201

Title: Lu D, et al. Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7.

Title: Zhou J, et al. Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactiveoxygen species. Toxicol Lett. 2013 Oct 24;222(2):139-45.

Title: Klose J, et al. Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model. PLoS One. 2019 Feb 14;14(2):e0211916.

Title: Wang F, et al. Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo. PLoS One. 2012; 7(12): e50638.

Title: Qu H, et al. Effect of salinomycin on metastasis and invasion of bladder cancer cell line T24. Asian Pac J Trop Med. 2015 Jul;8(7):578-82.

Title: Naujokat C, et al. Salinomycin as a drug for targeting human cancer stem cells. J Biomed Biotechnol. 2012;2012:950658.

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Tags:53003-10-4 Molecular Formula|53003-10-4 MDL|53003-10-4 SMILES|53003-10-4 Salinomycin