[1]EgyptianJournalofChemistry,2008,vol.51,p.113-123
[1]Locationinpatent:experimentalpartMohamed;Dossouki;Moustafa;Ghoname[EgyptianJournalofChemistry,2008,vol.51,#1,p.113-123]
[1]Locationinpatent:experimentalpartMohamed;Dossouki;Moustafa;Ghoname[EgyptianJournalofChemistry,2008,vol.51,#1,p.113-123]
[1]CurrentPatentAssignee:CHINARESOURCESNATIONALCORPORATION-CN106632032,2017,ALocationinpatent:Paragraph0087-0088
[2]CurrentPatentAssignee:CHINARESOURCESNATIONALCORPORATION-CN106854179,2017,ALocationinpatent:Paragraph0063;0092-0097
[3]CurrentPatentAssignee:WUHANZHIDUNTECHDEVELOPMENT-CN111018777,2020,ALocationinpatent:Paragraph0040;0045;0047;0052;0054;0059;0061;0066
Title: Use of locally delivered dequalinium chloride in the treatment of vaginal infections: a review.
Journal: Archives of gynecology and obstetrics 20160101
Title: Dequalinium blocks macrophage-induced metastasis following local radiation.
Journal: Oncotarget 20150929
Title: Dequalinium induces cytotoxicity in human leukemia NB4 cells by downregulation of Raf/MEK/ERK and PI3K/Akt signaling pathways and potentiation of specific inhibitors of these pathways.
Journal: Leukemia research 20140701
Title: Raf/MEK/ERK signaling inhibition enhances the ability of dequalinium to induce apoptosis in the human leukemic cell line K562.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120801
Title: Transferrin coupled vesicular system for intracellular drug delivery for the treatment of cancer: development and characterization.
Journal: Journal of drug targeting 20120501
Title: A comparison of dequalinium chloride vaginal tablets (Fluomizin®) and clindamycin vaginal cream in the treatment of bacterial vaginosis: a single-blind, randomized clinical trial of efficacy and safety.
Journal: Gynecologic and obstetric investigation 20120101
Title: N-palmitoyl-ethanolamine (PEA) induces peripheral antinociceptive effect by ATP-sensitive K+-channel activation.
Journal: Journal of pharmacological sciences 20120101
Title: Susceptibility testing of Atopobium vaginae for dequalinium chloride.
Journal: BMC research notes 20120101
Title: Dequalinium induces apoptosis in peripheral blood mononuclear cells isolated from human chronic lymphocytic leukemia.
Journal: Investigational new drugs 20111201
Title: Expression of GFP in the mitochondrial compartment using DQAsome-mediated delivery of an artificial mini-mitochondrial genome.
Journal: Pharmaceutical research 20111101
Title: Dequalinium induces human leukemia cell death by affecting the redox balance.
Journal: Leukemia research 20111001
Title: The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells.
Journal: Biomaterials 20110801
Title: Characterization of dequalinium as a XIAP antagonist that targets the BIR2 domain.
Journal: Apoptosis : an international journal on programmed cell death 20110501
Title: Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines.
Journal: Phytotherapy research : PTR 20110401
Title: Antimicrobial topical agents used in the vagina.
Journal: Current problems in dermatology 20110101
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens.
Journal: EMBO molecular medicine 20100901
Title: [The treatment of MRSA colonized middle ear; case report and literature review].
Journal: Laryngo- rhino- otologie 20100701
Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Journal: Nature chemical biology 20091001
Title: Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening.
Journal: Journal of biomolecular screening 20090701
Title: New method for the quantification of dequalinium cations in pharmaceutical samples by absorption and fluorescence diode array thin-layer chromatography.
Journal: Journal of chromatography. A 20090619
Title: Effect of dequalinium on the oxidative stress in Plasmodium berghei-infected erythrocytes.
Journal: Parasitology research 20090601
Title: Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels.
Journal: Journal of medicinal chemistry 20081211
Title: Determination of antibacterial quaternary ammonium compound in lozenges and human serum by resonance light scattering technique.
Journal: Journal of pharmaceutical and biomedical analysis 20081104
Title: Disintegration of amyloid fibrils of alpha-synuclein by dequalinium.
Journal: Biochimica et biophysica acta 20081001
Title: Initial SAR studies on apamin-displacing 2-aminothiazole blockers of calcium-activated small conductance potassium channels.
Journal: Bioorganic & medicinal chemistry letters 20081001
Title: Dequalinium-induced cell death of yeast expressing alpha-synuclein-GFP fusion protein.
Journal: Neurochemical research 20080701
Title: Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca(2+)-activated K(+) channel blockers.
Journal: Bioorganic & medicinal chemistry letters 20080601
Title: Electron crystallography reveals plasticity within the drug binding site of the small multidrug transporter EmrE.
Journal: Journal of molecular biology 20080404
Title: Synthesis and radioligand binding studies of bis-isoquinolinium derivatives as small conductance Ca(2+)-activated K(+) channel blockers.
Journal: Journal of medicinal chemistry 20071018
Title: Synthesis and pharmacological testing of polyaminoquinolines as blockers of the apamin-sensitive Ca2+-activated K+ channel (SK(Ca)).
Journal: Bioorganic & medicinal chemistry 20070815
Title: Mechanisms of relaxing response induced by rat/mouse hemokinin-1 in porcine coronary arteries: roles of potassium ion and nitric oxide.
Journal: European journal of pharmacology 20070813
Title: Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production.
Journal: Leukemia research 20070701
Title: Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes.
Journal: Bioorganic & medicinal chemistry 20070515
Title: Plasmodium berghei: in vitro and in vivo activity of dequalinium.
Journal: Experimental parasitology 20070101
Title: Inhibition of protein kinase C by dequalinium analogues: structure-activity studies on head group variations.
Journal: Bioorganic & medicinal chemistry 20061201
Title: Baclofen, an agonist at peripheral GABAB receptors, induces antinociception via activation of TEA-sensitive potassium channels.
Journal: British journal of pharmacology 20061101
Title: Dequalinium-induced protofibril formation of alpha-synuclein.
Journal: The Journal of biological chemistry 20060210
Title: [Treatment of urogenital infections in lower part of the genital organs in pregnant women which are at risk of miscarriage].
Journal: Likars'ka sprava 20060101
Title: Effects of the antitumoural dequalinium on NB4 and K562 human leukemia cell lines. Mitochondrial implication in cell death.
Journal: Leukemia research 20051001
Title: Mitochondrial leader sequence--plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria.
Journal: Mitochondrion 20051001
Title: Flow injection spectrofluorimetric study of the supramolecular interaction between beta-cyclodextrin and dequalinium chloride and its analytical application.
Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050701
Title: Induction of petite mutants in yeast Saccharomyces cerevisiae by the anticancer drug dequalinium.
Journal: Mutation research 20050502
Title: Pharmacology of acetylcholine-mediated cell signaling in the lateral line organ following efferent stimulation.
Journal: Journal of neurophysiology 20050501
Title: Tetraethylammonium exacerbates ischemic neuronal injury in rat cerebrocortical slice cultures.
Journal: European journal of pharmacology 20050131
Title: Type IVB piliated Salmonella typhi enhance IL-6 and NF-kappaB production in human monocytic THP-1 cells through activation of protein kinase C.
Journal: Immunobiology 20050101
Title: Bis-quinolinium cyclophanes: toward a pharmacophore model for the blockade of apamin-sensitive SKCa channels in sympathetic neurons.
Journal: Bioorganic & medicinal chemistry letters 20040816
Title: Defining determinant molecular properties for the blockade of the apamin-sensitive SKCa channel in guinea-pig hepatocytes: the influence of polarizability and molecular geometry.
Journal: Bioorganic & medicinal chemistry letters 20040802
Title: The receptor for activated C-kinase-I (RACK-I) anchors activated PKC-beta on melanosomes.
Journal: Journal of cell science 20040715
Title: Study of the involvement of K+ channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine.
Journal: European journal of pharmacology 20040628
Title: Cloning and expression of a small-conductance Ca(2+)-activated K+ channel from the mouse cochlea: coexpression with alpha9/alpha10 acetylcholine receptors.
Journal: Journal of neurophysiology 20040401
Title: State-dependent block of CNG channels by dequalinium.
Journal: The Journal of general physiology 20040301
Title: DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20030919
Title: In vivo biodistribution of erythrocytes and polyethyleneglycol-phosphatidylethanolamine micelles carrying the antitumour agent dequalinium.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20030901
Title: Small-conductance calcium-activated K+ channels are expressed in pancreatic islets and regulate glucose responses.
Journal: Diabetes 20030801
Title: Structural basis of multiple drug-binding capacity of the AcrB multidrug efflux pump.
Journal: Science (New York, N.Y.) 20030509
Title: Dequalinium: a novel, high-affinity blocker of CNGA1 channels.
Journal: The Journal of general physiology 20030101
Title: Activity of potassium channel-blockers in breast cancer.
Journal: Anticancer research 20030101
Title: Antimicrobial activity of dequalinium chloride against leading germs of vaginal infections.
Journal: Arzneimittel-Forschung 20020101
Title: Local treatment of vaginal infections of varying etiology with dequalinium chloride or povidone iodine. A randomised, double-blind, active-controlled, multicentric clinical study.
Journal: Arzneimittel-Forschung 20020101
Title: Isothermic titration calorimetry to study CMCs of neutral surfactants and of the liposome-forming bolaamphiphile dequalinium.
Journal: Journal of liposome research 20020101
Title: Structural mechanisms of QacR induction and multidrug recognition.
Journal: Science (New York, N.Y.) 20011207
Title: DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20010810
Title: Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells.
Journal: Advanced drug delivery reviews 20010702
Title: Cationic bolasomes with delocalized charge centers as mitochondria-specific DNA delivery systems.
Journal: Advanced drug delivery reviews 20010702
Title: Mitochondrial DNA metabolism targeting drugs.
Journal: Advanced drug delivery reviews 20010702
Title: Structure and design of polymeric surfactant-based drug delivery systems.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20010615
Title: Suramin prevents cerebellar granule cell-death induced by dequalinium.
Journal: Neurochemistry international 20010201
Title: Block of rat brain recombinant SK channels by tricyclic antidepressants and related compounds.
Journal: European journal of pharmacology 20000728
Title: The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines.
Journal: British journal of pharmacology 20000201
Title: Photoinduced inactivation of protein kinase C by dequalinium identifies the RACK-1-binding domain as a recognition site.
Journal: The Journal of biological chemistry 19980123
Title: Toxicity of the mitochondrial poison dequalinium chloride in a murine model system.
Journal: Journal of pharmaceutical sciences 19930301
Title: [Antimicrobial characteristics of a tincture of dequalinium chloride].
Journal: Annali di igiene : medicina preventiva e di comunita 19890101
Title: Dequalinium, a topical antimicrobial agent, displays anticarcinoma activity based on selective mitochondrial accumulation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19870801
Title: Kramer, W., [Treatment of tonsillitis with dequalinium chloride Fortschr Med, 1977. 95(16): p. 1108-10.
Title: Gamboa-Vujicic, G., et al., Toxicity of the mitochondrial poison dequalinium chloride in a murine model system. J Pharm Sci, 1993. 82(3): p. 231-5.
