+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 1369489-71-3
1369489-71-3,MFCD30502665
Catalog No.:AA019G97

1369489-71-3 | E-7046

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99%
in stock  
$11.00   $8.00
- +
5mg
99%
in stock  
$32.00   $22.00
- +
50mg
99%
in stock  
$170.00   $119.00
- +
100mg
99%
in stock  
$286.00   $200.00
- +
250mg
99%
in stock  
$475.00   $333.00
- +
1g
99%
in stock  
$1,248.00   $874.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA019G97
Chemical Name:
E-7046
CAS Number:
1369489-71-3
Molecular Formula:
C22H18F5N3O4
Molecular Weight:
483.3880
MDL Number:
MFCD30502665
SMILES:
O=C(c1c(nn(c1Oc1cccc(c1)C(F)(F)F)C)C(F)F)N[C@H](c1ccc(cc1)C(=O)O)C
Properties
Computed Properties
 
Complexity:
717  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
4.3  

Downstream Synthesis Route
Literature

Title: X. Bao, et al. Combination of a Novel EP4 Antagonist E7046 and Radiation Therapy Promotes Anti-tumor Immune Response and Tumor Rejection in Preclinical Tumor Models. International Journal of Radiation Oncology Biology Physics

Title: Diana I. Albu, et al. EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity. OncoImmunology.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1369489-71-3
Building Blocks
More >
Tags:1369489-71-3 Molecular Formula|1369489-71-3 MDL|1369489-71-3 SMILES|1369489-71-3 E-7046