804-30-8,MFCD00867383
Catalog No.:AA01CB9Y

804-30-8 | Fursultiamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$6.00   $4.00
- +
1g
98%
in stock  
$35.00   $24.00
- +
25g
98%
in stock  
$80.00   $56.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01CB9Y
Chemical Name:
Fursultiamine
CAS Number:
804-30-8
Molecular Formula:
C17H26N4O3S2
Molecular Weight:
398.5433
MDL Number:
MFCD00867383
SMILES:
OCC/C(=C(\N(Cc1cnc(nc1N)C)C=O)/C)/SSCC1CCCO1
Properties
Computed Properties
 
Complexity:
481  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
9  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
0.6  

Downstream Synthesis Route

[1]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1958,vol.78,p.602,603,604    Chem.Abstr.,1958,p.18424

Literature

Title: α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis.

Journal: The Journal of toxicological sciences 20170101

Title: The effect of thiamin tetrahydrofurfuryl disulfide on behavior of juvenile DBA/2J mice.

Journal: Neurotoxicology and teratology 20120301

Title: Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.

Journal: Brain : a journal of neurology 20100501

Title: A thiamin derivative inhibits oxidation of exogenous glucose at rest, but not during exercise.

Journal: Journal of nutritional science and vitaminology 20100101

Title: Thiamine tetrahydrofurfuryl disulfide improves energy metabolism and physical performance during physical-fatigue loading in rats.

Journal: Nutrition research (New York, N.Y.) 20091201

Title: A case of anorexia nervosa with Marchiafava-Bignami Disease that responded to high-dose intravenous corticosteroid administration.

Journal: Psychiatry research 20071115

Title: Human brain activation in response to olfactory stimulation by intravenous administration of odorants.

Journal: Neuroscience letters 20070809

Title: Stability of cyanocobalamin in sugar-coated tablets.

Journal: International journal of pharmaceutics 20070607

Title: Myopathy in thiamine deficiency: analysis of a case.

Journal: Journal of the neurological sciences 20061115

Title: Neuromagnetic changes of brain rhythm evoked by intravenous olfactory stimulation in humans.

Journal: Brain topography 20060101

Title: Peripheral neuropathy due to thiamine deficiency after inappropriate diet and total gastrectomy.

Journal: The Tokai journal of experimental and clinical medicine 20050901

Title: Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050601

Title: ST-segment elevation of electrocardiogram in a patient with Shoshin beriberi.

Journal: Internal medicine (Tokyo, Japan) 20050601

Title: Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20040901

Title: Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study.

Journal: Neuro endocrinology letters 20020801

Title: Kobayashi T, et al. Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis. Inflamm Res. 2005 Jun;54(6):249-55.

Title: Xiao-Yi Xiong, et al. Toll-Like Receptor 4/MyD88-Mediated Signaling of Hepcidin Expression Causing Brain Iron Accumulation, Oxidative Injury, and Cognitive Impairment After Intracerebral Hemorrhage. Circulation. 2016 Oct 4;134(14):1025-1038.

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SDS
Tags:804-30-8 Molecular Formula|804-30-8 MDL|804-30-8 SMILES|804-30-8 Fursultiamine
Catalog No.: AA01CB9Y
804-30-8,MFCD00867383
804-30-8 | Fursultiamine
Pack Size: 100mg
Purity: 98%
in stock
$6.00 $4.00
Pack Size: 1g
Purity: 98%
in stock
$35.00 $24.00
Pack Size: 25g
Purity: 98%
in stock
$80.00 $56.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA01CB9Y
Chemical Name: Fursultiamine
CAS Number: 804-30-8
Molecular Formula: C17H26N4O3S2
Molecular Weight: 398.5433
MDL Number: MFCD00867383
SMILES: OCC/C(=C(\N(Cc1cnc(nc1N)C)C=O)/C)/SSCC1CCCO1
Properties
Complexity: 481  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 26  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 9  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: 0.6  
Downstream Synthesis Route
67-03-8    804-30-8 

[1]YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1958,vol.78,p.602,603,604    Chem.Abstr.,1958,p.18424

Literature fold

Title: α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis.

Journal: The Journal of toxicological sciences20170101

Title: The effect of thiamin tetrahydrofurfuryl disulfide on behavior of juvenile DBA/2J mice.

Journal: Neurotoxicology and teratology20120301

Title: Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers.

Journal: Biological & pharmaceutical bulletin20110101

Title: Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice.

Journal: Brain : a journal of neurology20100501

Title: A thiamin derivative inhibits oxidation of exogenous glucose at rest, but not during exercise.

Journal: Journal of nutritional science and vitaminology20100101

Title: Thiamine tetrahydrofurfuryl disulfide improves energy metabolism and physical performance during physical-fatigue loading in rats.

Journal: Nutrition research (New York, N.Y.)20091201

Title: A case of anorexia nervosa with Marchiafava-Bignami Disease that responded to high-dose intravenous corticosteroid administration.

Journal: Psychiatry research20071115

Title: Human brain activation in response to olfactory stimulation by intravenous administration of odorants.

Journal: Neuroscience letters20070809

Title: Stability of cyanocobalamin in sugar-coated tablets.

Journal: International journal of pharmaceutics20070607

Title: Myopathy in thiamine deficiency: analysis of a case.

Journal: Journal of the neurological sciences20061115

Title: Neuromagnetic changes of brain rhythm evoked by intravenous olfactory stimulation in humans.

Journal: Brain topography20060101

Title: Peripheral neuropathy due to thiamine deficiency after inappropriate diet and total gastrectomy.

Journal: The Tokai journal of experimental and clinical medicine20050901

Title: Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20050601

Title: ST-segment elevation of electrocardiogram in a patient with Shoshin beriberi.

Journal: Internal medicine (Tokyo, Japan)20050601

Title: Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent.

Journal: Medical science monitor : international medical journal of experimental and clinical research20040901

Title: Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study.

Journal: Neuro endocrinology letters20020801

Title: Kobayashi T, et al. Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis. Inflamm Res. 2005 Jun;54(6):249-55.

Title: Xiao-Yi Xiong, et al. Toll-Like Receptor 4/MyD88-Mediated Signaling of Hepcidin Expression Causing Brain Iron Accumulation, Oxidative Injury, and Cognitive Impairment After Intracerebral Hemorrhage. Circulation. 2016 Oct 4;134(14):1025-1038.

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