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99705-65-4,MFCD10565902
Catalog No.:AA01CBLE

99705-65-4 | 2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-,hydrochloride, (4aR,10bR)-

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2mg
99%
in stock  
$274.00   $192.00
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5mg
99%
in stock  
$362.00   $254.00
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25mg
99%
in stock  
$1,138.00   $797.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CBLE
Chemical Name:
2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-,hydrochloride, (4aR,10bR)-
CAS Number:
99705-65-4
Molecular Formula:
C15H22ClNO2
Molecular Weight:
283.7937
MDL Number:
MFCD10565902
SMILES:
CCCN1CCOC2C1CCC3=C2C=C(C=C3)O.Cl
Properties
Computed Properties
 
Complexity:
284  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  

Literature

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Title: A study of phase separation in peptide-loaded HPMC films using T(zero)-modulated temperature DSC, atomic force microscopy, and scanning electron microscopy.

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Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040501

Title: The use of polymer-based electrospun nanofibers containing amorphous drug dispersions for the delivery of poorly water-soluble pharmaceuticals.

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Title: Prediction of drug release from HPMC matrices: effect of physicochemical properties of drug and polymer concentration.

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Title: Evaluation of ophthalmic suspensions using surface tension.

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Title: Evaluation of novel one-step dry-coated tablets as a platform for delayed-release tablets.

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Title: Hot-melt extruded ethylcellulose cylinders containing a HPMC-Gelucire core for sustained drug delivery.

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Title: Development and evaluation of buccoadhesive propranolol hydrochloride tablet formulations: effect of fillers.

Journal: Farmaco (Societa chimica italiana : 1989) 20040201

Title: Oxidative tissue damage after phacoemulsification: influence of ophthalmic viscosurgical devices.

Journal: Journal of cataract and refractive surgery 20040201

Title: Penetration-enhancing effect of ethanol-water solvent system and ethanolic solution of carvone on transdermal permeability of nimodipine from HPMC gel across rat abdominal skin.

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Title: Modified release bi-layered tablet of melatonin using beta-cyclodextrin.

Journal: Die Pharmazie 20030901

Title: Effect of carvone on the permeation of nimodipine from a membrane-moderated transdermal therapeutic system.

Journal: Die Pharmazie 20030801

Title: Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of celecoxib through human skin.

Journal: Die Pharmazie 20030501

Title: Endotoxins in ophthalmic viscosurgical devices.

Journal: European journal of ophthalmology 20030301

Title: Polymethacrylate salts as new low-swellable mucoadhesive materials.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20030214

Title: Influence of enteric citric acid on the release profile of 4-aminopyridine from HPMC matrix tablets.

Journal: International journal of pharmaceutics 20030130

Title: Gentamicin release from modified acrylic bone cements with lactose and hydroxypropylmethylcellulose.

Journal: Biomaterials 20030101

Title: Preparation and release characteristics of polymer-coated and blended alginate microspheres.

Journal: Journal of microencapsulation 20030101

Title: Effect of curing conditions and plasticizer level on the release of highly lipophilic drug from coated multiparticulate drug delivery system.

Journal: Pharmaceutical development and technology 20030101

Title: Characterization of a female controlled drug delivery system for microbicides.

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Title: [Studies on heart-protecting musk pH-dependent gradient-release pellets].

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Title: The effect of viscosity on the perception of flavour.

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Title: [Preparation and in vitro release of tetramethylpyrazine phosphate pulsincap capsule controlled by an erodible plug].

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Title: Characterization of nifedipine solid dispersions.

Journal: International journal of pharmaceutics 20020821

Title: Caffeine microparticles for nasal administration obtained by spray drying.

Journal: International journal of pharmaceutics 20020821

Title: Effect of formulation variables on the floating properties of gastric floating drug delivery system.

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Title: [Preparation of buspirone hydrochloride buccal adhesive tablet and study on its drug release mechanism].

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Title: Release of ketoprofen enantiomers from HPMC K100M matrices--diffusion studies.

Journal: International journal of pharmaceutics 20020604

Title: A local delivery system for fentanyl based on biodegradable poly(L-lactide-co-glycolide) oligomer.

Journal: International journal of pharmaceutics 20020604

Title: Combined lidocaine 1% and hydroxypropyl methylcellulose 2.25% as a single anesthetic/ viscoelastic agent in phacoemulsification.

Journal: Journal of cataract and refractive surgery 20020501

Title: The effect of controlled release tablet performance and hydrogel strength on in vitro/in vivo correlation.

Journal: Pharmaceutical development and technology 20020501

Title: Investigation of excipient type and level on drug release from controlled release tablets containing HPMC.

Journal: Pharmaceutical development and technology 20020501

Title: Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literature.

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Title: Studies on solubility and hypoglycemic activity of gliclazide beta-cyclodextrin-hydroxypropylmethylcellulose complexes.

Journal: Die Pharmazie 20020301

Title: Modulation of active pharmaceutical material release from a novel 'tablet in capsule system' containing an effervescent blend.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20020219

Title: Enteric coated HPMC capsules designed to achieve intestinal targeting.

Journal: International journal of pharmaceutics 20020101

Title: In vitro evaluation of pectin-HPMC compression coated 5-aminosalicylic acid tablets for colonic delivery.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020101

Title: Studies in release behavior of diltiazem HCl from matrix tablets containing (hydroxypropyl)methyl cellulose and xanthan gum.

Journal: Bollettino chimico farmaceutico 20020101

Title: A new drug delivery system using plasma-irradiated pharmaceutical aids. IX. Controlled-release of theophylline from double-compressed tablet composed of cellulose derivatives as wall material.

Journal: Chemical & pharmaceutical bulletin 20011201

Title: Processing factors in development of solid solution formulation of itraconazole for enhancement of drug dissolution and bioavailability.

Journal: International journal of pharmaceutics 20011023

Title: Investigation of the influence of mean HPMC particle size and number of polymer particles on the release of aspirin from swellable hydrophilic matrix tablets.

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Title: Effect of nicotinamide on the properties of aqueous HPMC solutions.

Journal: International journal of pharmaceutics 20010911

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Title: Effect of anionic polymers on the release of propranolol hydrochloride from matrix tablets.

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Title: Passive targeting of doxorubicin with polymer coated liposomes in tumor bearing rats.

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Title: Controlled and complete release of a model poorly water-soluble drug, prednisolone, from hydroxypropyl methylcellulose matrix tablets using (SBE)(7m)-beta-cyclodextrin as a solubilizing agent.

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Title: Development of a mucoadhesive dosage form for vaginal administration.

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Journal: Journal of controlled release : official journal of the Controlled Release Society 20010129

Title: Preparation of redispersible dry emulsions by spray drying.

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Journal: International journal of pharmaceutics 20010116

Title: Penetration enhancement of ibuprofen from supersaturated solutions through human skin.

Journal: International journal of pharmaceutics 20010105

Title: Effect of FITC-dextran molecular weight on its release from floating cetyl alcohol and HPMC tablets.

Journal: The Journal of pharmacy and pharmacology 20010101

Title: Naproxen availability from variable-dose and weight sustained-release tablets.

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SDS
Tags:99705-65-4 Molecular Formula|99705-65-4 MDL|99705-65-4 SMILES|99705-65-4 2H-Naphth[1,2-b]-1,4-oxazin-9-ol, 3,4,4a,5,6,10b-hexahydro-4-propyl-,hydrochloride, (4aR,10bR)- |Heterocyclic_Building_Blocks