Name: Name:Larazotide Acetate
Brand: AABLOCKS
SKU: AA01CC09
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA01CC09

Chemical Name: Larazotide Acetate

CAS Number: 881851-50-9

Molecular Formula: C34H59N9O12

Molecular Weight: 785.8854

MDL Number: MFCD31630844

SMILES: CC(=O)O.NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)O)CCC(=O)N)C(C)C)CC(C)C)C(C)C

Properties

Complexity: 1320

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 5

Heavy Atom Count: 55

Hydrogen Bond Acceptor Count: 13

Hydrogen Bond Donor Count: 10

Rotatable Bond Count: 21

Literature fold

Title: AT-1001: a high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20120501

Title: Co-administration with the pharmacological chaperone AT1001 increases recombinant human α-galactosidase A tissue uptake and improves substrate reduction in Fabry mice.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy20120401

Title: The influence of AT1002 on the nasal absorption of molecular weight markers and therapeutic agents when co-administered with bioadhesive polymers and an AT1002 antagonist, AT1001.

Journal: The Journal of pharmacy and pharmacology20120101

Title: Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse.

Journal: Gut20080101

Title: The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study.

Journal: Alimentary pharmacology & therapeutics20070901

Title: Gopalakrishnan S, et al. Larazotide acetate regulates epithelial tight junctions in vitro and in vivo. Peptides. 2012 May;35(1):86-94.

881851-50-9 | Larazotide Acetate